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| 1 | A new iridoid from Incarvillea delavayi显示文摘新 iridoid 从 Incarvillea delavayi 的整个植物的 80% 乙醇摘录被孤立。它的结构被定义,并且把 incarvillic 称为酸,根据光谱证据。 | Tao Lu Wei Dong Zhang Yue Hu Pei Chuan Zhang Jin Cheng Li YunHeng Shen | 2007 | Chinese Chemical Letters2007，18，12： | 9 |
| 2 | Combination of olfactory test and substantia nigra transcranial sonopraphy in the differential diagnosis of Parkinson’s disease:a pilot study from China显示文摘Objectives:Both hyposmia and substania nigra(SN)hyperechogenicity on trascranial sonography(TCS)were risk markers for idiopathic Parkinson’s disease(PD),which was beneficial to the differential diagnosis of the disease.However,each of their single diagnostic value is often limited.The purpose of present study was to explore whether the combination of olfactory test and TCS of SN could enhance the differential diagnostic power in Chinese patients with PD.Methods:Thirty-seven patients with PD and twenty-six patients with essential tremor(ET)were evaluated on 16-item odor identification test from extended version of sniffin’sticks and TCS of SN.The frequency of hyposmia and SN hyperechogenicity in each group was compared.The sensitivity,specificity,positive predictive value(PPV)and negative predictive value(NPV)of the two clinical biomarkers were analyzed.Results:The frequency of hyposmia in patients with PD was significantly higher than in patients with ET(62.2%VS.3.8%,P=0.000).The frequency of SN hyperechogenicity in patients with PD was significantly higher than in ET subjects(48.6%VS.15.4%,P=0.006).The combination of hyposmia and SN hyperechogenicity(if either one or both present)discriminated patients with PD from ET with a sensitivity of 78.4%and 29.7%,specificity of 80.8%and 100%,PPV of 85.3%and 100%,and NPV of 72.4%and 50.0%,respectively.Conclusions:Our preliminary data suggested that the combination of hyposmia and SN hyperechogenicity could improve the diagnostic potential for discriminating Chinese patients with PD from ET. | Wei Chen Yu-Yan Tan Yun-Yun Hu Wei-Wei Zhan Li Wu Yue Lou Xi Wang Yi Zhou Pei Huang Yuan Gao Qin Xiao Sheng-Di Chen | 2012 | Translational Neurodegeneration2012，1，1： | 6 |
| 3 | Eremophilane sesquiterenes from the marine fungus Penicillium sp.BL27-2显示文摘六 eremophilane sesquiterpenes 从海洋的真菌毛丛 sp 被获得。BL27-2。他们的结构作为 3-acetyl-9 被阐明, 7 (11 )-dien-7-hydroxy-8-oxoeremophilane (1 ) , 3-acetyl-13-deoxyphomenone (2 ) , Sporogen-AO 1 (3 ) , 7-hydroxypetasol (4 ) , 8-hydroxy-13-deo -xyphomenone (5 ) 和基于详细 NMR 分析的 6-dehydropetasol (6 ) 。1 是新混合物, 2 作为新自然混合物被获得。这些混合物是为他们由 MTT 方法的 P388, A549, HL60, BEL7402 和 K562 房间线上的细胞毒素的活动的 assayed。试金结果建议在 eremophilane 分子的二环环氧化物戒指为他们的活动是必要的,并且乙酰化能提高他们的活动。 | Yong Fu Huang Li Qiao A. Li Lv Yue Hu Pei Li Tian | 2008 | Chinese Chemical Letters2008，19，5： | 6 |
| 4 | A New Chromone Derivative from Stellera chamaejasme L显示文摘A new chromone derivative, 3-[1- (2, 4, 6-trihydroxyphenyl) 3-di-(4-hydroxyphenyl) 1-propanone-2-yl] 5,7-dihydroxy-8-di(4-hydroxyphenyl)methyl-4H-1-benzopyran-4-one, named as isomohsenone was isolated from the roots of Stellera chamaejasme L. together with known chamaechromone. Its structure was determined by the analysis of MS and NMR data, especially 2D NMR spectra. | Bao Min FENG, Yue Hu PEI*, Hui Ming HUA School of Traditional Chinese Medicines, Shenyang Pharmaceutical University, Shenyang 110016 | 2002 | Chinese Chemical Letters2002，13，8： | 6 |
| 5 | A new cytotoxic caged polyprenylated xanthone from the resin of Garcinia hanburyi显示文摘新将关入笼中的 polyprenylated 氧杂蒽酮, gambogic 醛(1 ) ,从 Garcinia hanburyi 的树脂被孤立。它的结构被阐明根据光谱数据包括 1D 和 2D NMR 数据。另外,化合物 1 的 antiproliferative 能力在老鼠白血病 P388 和 P388/ADR 房间被决定。 | Li Li Wang Zhan Lin Li Yong Peng Xu Xiao Qiu Liu Yue Hu Pei Yong Kui Jing Hui Ming Hua | 2008 | Chinese Chemical Letters2008，19，10： | 5 |
| 6 | A New xanthene from Blumea riparia显示文摘A new xanthene, named blumeaxanthene, was isolated from Blumea riparia DC. The structure was elucidated on the basis of the data of NMR, MS, IR. | Jia Qing Cao Yao Yao Huan Chen Li Qiao Yu Zhi Zhou Yue Hu Pei | 2007 | Chinese Chemical Letters2007，18，3： | 4 |
| 7 | One new bufadienolide biotransformed from cinobufagin by Cunninghamella elegans显示文摘Cunninghamella elegans 被采用了让华蟾蜍精(1 ) 的简历转变负担得起一代谢物。转变产品的结构作为 7 β被描绘了, 12 β - dihydroxylcinobufagin (2 ) 。产品 2 是新混合物。在 vitro,简历转变产品和 substrate-cinobufagin 的细胞毒素的活动是对 HeLa 的 assayed;他们都显示出细胞毒素的活动。 | Li Qiao Yu Zhi Zhou Huan Chen Jia Qing Cao Yue Hu Pei | 2008 | Chinese Chemical Letters2008，19，3： | 3 |
| 8 | Intestinal dysbiosis exacerbates the pathogenesis of psoriasis-like phenotype through changes in fatty acid metabolism显示文摘The intestinal microbiota has been associated with host immunity as well as psoriasis;however,the mechanism of intestinal microbiota regulating psoriasis needs to be demonstrated systematically.Here,we sought to examine its role and mechanism of action in the pathogenesis of psoriasis.We found that the severity of psoriasis-like skin phenotype was accompanied by changes in the composition of the intestinal microbiota.We performed co-housing and fecal microbial transplantation(FMT)experiments using the K14-VEGF transgenic mouse model of psoriasis and demonstrated that the transfer of intestinal microbiota from mice with severe psoriasis-like skin phenotype exacerbated psoriasiform skin inflammation in mice with mild symptoms,including increasing the infiltration and differentiation of Th17,and increased the abundance of Prevotella,while decreasing that of Parabacteroides distasonis,in the colon.These alterations affected fatty acid metabolism,increasing the abundance of oleic and stearic acids.Meanwhile,gentamicin treatment significantly reduced the abundance of Prevotella and alleviated the psoriasis-like symptoms in both K14-VEGF mice and imiquimod(IMQ)-induced psoriasis-like mice.Indeed,administration of oleic and stearic acids exacerbated psoriasis-like symptoms and increased Th17 and monocyte-derived dendritic cell infiltration in the skin lesion areas in vivo,as well as increased the secretion of IL-23 by stimulating DCs in vitro.At last,we found that,treatment of PDE-4 inhibitor alleviated psoriasis-like phenotype of K14-VEGF mice accompanied by the recovery of intestinal microbiota,including the decrease of Prevotella and increase of Parabacteroides distasonis.Overall,our findings reveal that the intestinal microbiota modulates host metabolism and psoriasis-like skin inflammation in mice,suggesting a new target for the clinical diagnosis and treatment of psoriasis. | Qixiang Zhao Jiadong Yu Hong Zhou Xiaoyan Wang Chen Zhang Jing Hu Yawen Hu Huaping Zheng Fanlian Zeng Chengcheng Yue Linna Gu Zhen Wang Fulei Zhao Pei Zhou Haozhou Zhang Nongyu Huang Wenling Wu Yifan Zhou Jiong Li | 2023 | Signal Transduction and Targeted Therapy2023，8，2： | 2 |
| 9 | A New Monoterpene Glucoside from the Leaves of Betula platyphylla Suk.显示文摘A new monoterpene glucoside, (2E,6Z)-2,6-dimethyl-8-(-D-glucosyloxy-2,6-octadien- oic acid, was isolated from the leaves of Betula platyphylla Suk. The structure was established by spectroscopic data. | Su Juan WANG, Yue Hu PEI*, Hui Ming HUA Department of Natural Products Chemistry, Shenyang Pharmaceutical University, Shenyang 110015 | 2001 | Chinese Chemical Letters2001，12，4： | 2 |
| 10 | A New Caffeoylquiniclactone, Neochlorgeniclatone from the Leaves of Betula platyphylla Suk.显示文摘A new caffeoylquiniclactone, named neochlorgeniclatone, was isolated from the leaves of Betula platyphylla Suk. The structure was established by spectroscopic data. | Su Juan WANG, Yue Hu PEI*, Hui Ming HUA Department of Natural Products Chemistry, Shenyang Pharmaceutical University, Shenyang 110015 | 2001 | Chinese Chemical Letters2001，12，6： | 2 |
| 11 | NEW COMPOUNDS FROM PEUCEDANUM PRAERUPTORUM显示文摘Four new compounds named qianhucoumarins E, F, G and baihuaqianhuoside have been isolated from the root of Peucedanum praeruptorum. Their structures were elucidated by chemical evidences and spectral analysis. | Ling Yi KONG Yue Hu PEI Xian LI~* and Ting Ru ZHU Research Department of Naturat Medicine, Shenyang College of Pharmacy, Shenyang, 110015 | 1993 | Chinese Chemical Letters1993，4，1： | 2 |
| 12 | NEW COUMARINS FROM PEUCEDANUM PRAERUPTORUM显示文摘Four new coumarins named qianhucoumarins A, B, C, D have been isolated from traditional Chinese medicine-the root of Peucedanum praeruptorum. Their structures were elucidated by chemical evidences and spectral analysis. | Ling Yi KONG Yue Hu PEI Xian LI~* and Ting Ru ZHU Research Departmen of Natural. Medicine, shenyang College of Pharmacy, Shenyang, 110015 | 1993 | Chinese Chemical Letters1993，4，1： | 1 |
| 13 | Comparisons of the Paleo-Mesoproterozoic large igneous provinces and black shales in the North China and North Australian cratons显示文摘Comparisons of large igneous provinces(UPs)and black shales from different cratons can provide important constraints on Precambrian paleogeographic reconstructions and a better understanding of the environmental effects of large-scale volcanic events.A comparison of intraplate mafic events mostly interpreted as LIPs or portions of LIPs(LIP fragments/remnants due to continental breakup or erosion)from the North China Craton(NCC)and North Australian Craton(NAC)shows good correlation in the age range from 1800 Ma to 1300 Ma,and four robust age matches at ca.1790-1770 Ma,ca.1730 Ma,ca.1680-1670 Ma and ca.1320 Ma have been identified.Most notably,the coeval ca.1320 Ma Yanliao LIP in the eastern-northern NCC and the Derim Derim-Galiwinku LIP in the NAC are also characterized by similar field occurences and dominantly subalkaline tholeiitic basalts and intraplate geochemical compositions,and are interpreted as portions of the same LIP,separated by continental breakup.Subsequent to 1300 Ma,the NCC and NAC exhibit very different magmatic histories,indicating that separation of these two cratons occurred,likely subsequent to the ca.1320 Ma LIP event.A comparison of Paleo-Mesoproterozoic black shales from the NCC and NAC provides further evidence for close connections between these regions during this period.Black shales of the Chuanlianggou Formation in the northern NCC and the Cuizhuang Formation in the southern NCC were deposited in the age range ca.1650-1635 Ma and can be correlated with ca.1640-1635 Ma black shales in the Barney Creek Formation of the NAC.Deposition of black shales within the Xiamaling Formation in the NCC and the Velkerri and Kyalla formations of the McArthur Basin in the NAC occurred synchronously at ca.1380-1360 Ma.Our results from matching of LIP ages and black shales combined with paleomagnetic data show that the northern-northeastern margin of the NCC was connected to the northern margin of the NAC from ca.1800 Ma to 1300 Ma.This long-lived late Paleoproterozoic to mid-Mesoproterozoic connection lasted for at least 500 million years until separation of the NCC from the NAC between ca.1320 and ca.1230-1220 Ma. | Shuan-Hong Zhang Richard E.Ernst Tim J.Munson Junling Pei Guohui Hu Jian-Min Liu Qi-Qi Zhang Yu-Hang Cai Yue Zhao | 2022 | Fundamental Research2022，2，1： | 1 |
| 14 | Triterpenoids from the Resin of Styrax tonkinensis and Their Antiproliferative and Differentiation Effects in Human Leukemia HL-60 Cells显示文摘 | Wang Feng Hua Hui - ming Pei Yue - hu | 2006 | Journal of Natural Products2006，69，5： | 1 |
| 15 | The First High-quality Reference Genome of Sika Deer Provides Insights into High-tannin Adaptation显示文摘Sika deer are known to prefer oak leaves,which are rich in tannins and toxic to most mammals;however,the genetic mechanisms underlying their unique ability to adapt to living in the jungle are still unclear.In identifying the mechanism responsible for the tolerance of a highly toxic diet,we have made a major advancement by explaining the genome of sika deer.We generated the first high-quality,chromosome-level genome assembly of sika deer and measured the correlation between tannin intake and RNA expression in 15 tissues through 180 experiments.Comparative genome analyses showed that the UGT and CYP gene families are functionally involved in the adaptation of sika deer to high-tannin food,especially the expansion of the UGT family 2 subfamily B of UGT genes.The first chromosome-level assembly and genetic characterization of the tolerance to a highly toxic diet suggest that the sika deer genome may serve as an essential resource for understanding evolutionary events and tannin adaptation.Our study provides a paradigm of comparative expressive genomics that can be applied to the study of unique biological features in non-model animals. | Xiumei Xing Cheng Ai Tianjiao Wang Yang Li Huitao Liu Pengfei Hu Guiwu Wang Huamiao Liu Hongliang Wang Ranran Zhang Junjun Zheng Xiaobo Wang Lei Wang Yuxiao Chang Qian Qian Jinghua Yu Lixin Tang Shigang Wu Xiujuan Shao Alun Li Peng Cui Wei Zhan Sheng Zhao Zhichao Wu Xiqun Shao Yimeng Dong Min Rong Yihong Tan Xuezhe Cui Shuzhuo Chang Xingchao Song Tongao Yang Limin Sun Yan Ju Pei Zhao Huanhuan Fan Ying Liu Xinhui Wang Wanyun Yang Min Yang Tao Wei Shanshan Song Jiaping Xu Zhigang Yue Qiqi Liang Chunyi Li Jue Ruan Fuhe Yang | 2023 | Genomics, Proteomics & Bioinformatics2023，21，1： | 1 |
| 16 | A New Macrocyclic Trichochecene from Soil Fungus显示文摘From fermentation broth of soil fungus 254-2 obtained from Yunnan province, a new macrocylic trichochecene was isolated. The structure was determined on the basis of spectroscopic evidences especially the 2-D NMR spectra. | Tao WANG, Yi ZHANG, Yue Hu PEI*, Hui Ming HUA, Bao Min FENG Department of Natural Products Chemistry, Shenyang Pharmaceutical University, Shenyang 110016 | 2002 | Chinese Chemical Letters2002，13，1： | 1 |
| 17 | Printed hole-conductor-free mesoscopic perovskite solar cells with excellent long-term stability using PEAI as an additive显示文摘Phenethylamine(PEA) was successfully introduced into hole-conductor-free, fully printable mesoscopic MAPbI3 perovskite solar cells(MPSCs) with a carbon electrode by mixing phenethylammonium iodide with MAPbI3 perovskite solution. PEA-MAPbI3 films show better pore filling into TiO2 scaffold that forms better contact, and induce longer exciton lifetime and higher quantum efficiency of photoinduced charge separation. As a result, the power conversion efficiency of PEA-MAPbI3 MPSCs is 37% higher than that of MAPbI3 MPSCs. And PEA-MAPbI3 MPSCs show excellent long-term stability that could keep 90% of origin power conversion efficiency for over 80 days in the air. | Cong Xua Zheling Zhang Yue Hu Yusong Sheng Pei Jiang Hongwei Han Jian Zhang | 2018 | Journal of Energy Chemistry2018，27，3： | 1 |
| 18 | Perspective on powder technology for all-solid-state batteries:How to pair sulfide electrolyte with high-voltage cathode显示文摘Sulfide solid electrolytes(SEs)have attracted ever-increasing attention due to their superior roomtemperature ionic conductivity(~10^(-2) S cm^(-1)).Additionally,the integration of sulfide SEs and highvoltage cathodes is promising to achieve higher energy density.However,the incompatible interfaces between sulfide SEs and high-voltage cathodes have been one of the key factors limiting their applications.Therefore,this review presents a critical summarization of the interfacial issues in all-solid-state lithium batteries based on sulfide SEs and high-voltage cathodes and proposes strategies to stabilize the electrolyte/cathode interfaces.Moreover,the future research direction of electrolyte/cathode interfaces and application prospects of powder technology in sulfide-based ASSLBs were also discussed. | Jiangkui Hu Shijie Yang Yingying Pei Xilong Wang Yulong Liao Shuai Li Aolong Yue Jia-Qi Huang Hong Yuan | 2024 | Particuology2024，86，3： | 0 |
| 19 | Novel Antifungal Antibiotic, WB Produced by the Fungus Strain 38显示文摘WB, a new antifungal antibiotic, was isolated from the soil fungus strain 38 againstPyricularta oryzae, and its structure was elucidated as 2-[(E)-3,5-dimethyl-3,4-dihydrox-1-eptylenyl]-4-chloro-5-oxo-6-methyl-6,7-dihydroxy-5,6,7,7’-4H-benzo[d]-2H-pyran on the basis of1H-NMR, 13C-NMR, DEPT, HMQC, 1H-13H COSY, HMBC spectra. | Jun YANG Xiu Lan QI Gang SHAO Yue Hu PEI Xin Sheng YAO (Department of Natural Medicinal Chemistry, Shenyang Pharmaceutical University Shenyang 110015)Susumu KITANAKA (Department of Pharmacognosy, College of Pharmacy, Nihon University, Japan) | 1998 | Chinese Chemical Letters1998，9，9： | 0 |
| 20 | Injury Morbidity between 2013 and 2018 in Hunan Province,China显示文摘Accurate and timely injury statistics are critical to assess the severity of public health problems.Such statistics allow researchers,practitioners,and policymakers to determine morbidity and mortality rate disparities across socio-demographic subgroups and to evaluate rate changes over time. | WANG Wan Hui GAO De Yue HUA Jun Jie NING Pei Shan SCHWEBEL David C HU Guo Qing | 2022 | Biomedical and Environmental Sciences2022，35，3： | 0 |
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