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| 1 | BRF1 ameliorates LPS-induced inflammation through autophagy crosstalking with MAPK/ ERK signaling显示文摘Inflammation is indispensable for host defense,whereas excessive inflammation often develop inflammatory diseases.Autophagy is thought to be engaged in many extracellular stress responses,such as starvation and innate immunity.Thus,autophagy plays an important role in maintaining homeostasis.The purpose of this study was to elucidate the function of BRF1 in the regulation of inflammation and autophagy response in macrophages.We found that BRF1 inhibited the LPS-induced inflammatory factors expression and the autophagy flux in macrophage.Furthermore,inhibition autophagy with 3-MA can attenuate the suppressive effect of BRF1 on LPS-mediated inflammation.In addition,MAPK/ERK signaling pathway was involved in the BRF1 inhibition inflammation and autophagy in macrophages.These findings indicate that BRF1 attenuates LPS-induced inflammatory factors secretion through autophagy,at least in part,through MAPK/ERK signaling pathway. | Weiwei Xie Wei Zheng Min Liu Qizhong Qin Yunpeng Zhao Zhi Cheng Fengjin Guo | 2018 | Genes & Diseases2018,5,3: | 9 |
| 2 | Solvent extraction and separation of light rare earths from chloride media using HDEHP-P350 system显示文摘Solvent extraction is the most important method for rare earth extraction and separation.Currently,di(2-ethylhexyl)phosphoric acid(HDEHP)and 2-ethylhexyl phosphonic acid mono-2-ethylhexyl ester(HEH/EHP)are widely used in industrial production,but there are still obvious deficiencies that require further research to resolve.In this paper,the unsaponification extraction of light rare earth ions in a hydrochloric acid medium by di(2-ethylhexyl)phosphoric acid-di(1-methyl-heptyl)methyl phosphonate(HDEHPP350)system was studied.The results show that the addition of P350 reduces the extraction capacity of HDEHP,and also greatly reduces the concentration of acidity required for the back-extraction.It still has a good separation factor for light rare earths without saponification,and the extractant is not easy to emulsify.With an aqueous phase of pH=2.85,and HDEHP mole fraction XHDEHP=0.9(compared with O/A=2),the separation effect of light rare earth is the best,resulting in the separation coefficientβCe/La=3.39,βPr/Ce=1.67 andβNd/Pr=1.45,respectively.The loaded light rare earth ions extracted by HDEHP-P350 can be easily stripped when 2 mol/L HCl is used as the stripping agent.Finally,the extraction mechanism is discussed using a slope method,and the final structure of the extracted complex is determined to be RECl[(DEHP)_(2)]_(2)P350_((o)),based on a combination of infrared spectra and 1 H NMR and 31P NMR analyses. | Wenjie Zhang Dongxia Feng Xian Xie Xiong Tong Yunpeng Du Yang Cao | 2022 | Journal of Rare Earths2022,40,2: | 3 |
| 3 | Induced pluripotent stem cells:Landscape for studying and treating hereditary hearing loss显示文摘Hearing loss(HL) is one of the most widespread sensory disorders,affecting approximately 1 in 500 newborns.Heritable diseases of the inner ear are the leading causes of prelingual HL.Treating of hereditary HL and understanding its underlying mechanisms remain difficult challenges to otolaryngologists.As stem cells are capable of self-renewal and differentiation,they are ideally suited both for disease modeling and regenerative medicine.Recently,description of induced pluripotent stem cells(iPSCs) has allowed the field of disease modeling and personalized therapy to become far more accessible and physiologically relevant,as iPSCs can be generated from patients of any genetic background.This review briefly describes the advantages of iPSCs technology and discusses potential applications of this powerful biological tool in studying and treating hereditary HL. | Tao Peng Yunpeng Dong Ganghua Zhu Dinghua Xie | 2014 | Journal of Otology2014,9,4: | 2 |
| 4 | Electrochemical CO_(2) mineralization for red mud treatment driven by hydrogen-cycled membrane electrolysis显示文摘CO_(2)mineralization as a promising CO_(2)mitigation strategy can employ industrial alkaline solid wastes to achieve net emission reduction of atmospheric CO_(2).The red mud is a strong alkalinity waste residue produced from the aluminum industry by the Bayer process which has the potential for the industrial CO_(2)large scale treatment.However,limited by complex components of red mud and harsh operating conditions,it is challenging to directly mineralize CO_(2)using red mud to recover carbon and sodium resources and to produce mineralized products simultaneously with high economic value efficiently.Herein,we propose a novel electrochemical CO_(2)mineralization strategy for red mud treatment driven by hydrogen-cycled membrane electrolysis,realizing mineralization of CO_(2)efficiently and recovery of carbon and sodium resources with economic value.The system utilizes H_(2)as the redox-active proton carrier to drive the cathode and anode to generate OH^(-) and H^(+) at low voltage,respectively.The H^(+) plays as a neutralizer for the alkalinity of red mud and the OH^(-) is used to mineralize CO_(2)into generate highpurity NaHCO_(3)product.We verify that the system can effectively recover carbon and sodium resources in red mud treatment process,which shows that the average electrolysis efficiency is 95.3%with highpurity(99.4%)NaHCO_(3)product obtained.The low electrolysis voltage of 0.453 V is achieved at10 mA·cm^(-2) in this system indicates a potential low energy consumption industrial process.Further,we successfully demonstrate that this process has the ability of direct efficient mineralization of flue gas CO_(2)(15%volume)without extra capturing,being a novel potential strategy for carbon neutralization. | Heping Xie Yunpeng Wang Tao Liu Yifan Wu Wenchuan Jiang Cheng Lan Zhiyu Zhao Liangyu Zhu Dongsheng Yang | 2022 | Chinese Journal of Chemical Engineering2022,35,3: | 2 |
| 5 | Intestinal farnesoid X receptor signaling promotes nonalcoholic fatty liver disease显示文摘 | Jiang Changtao Xie Cen Li Fei Zhang Limin Nichols Robert G Krausz Kristopher W Cai Jingwei Qi Yunpeng Fang Zhong-Ze Takahashi Shogo Tanaka Naoki Desai Dhimant Amin Shantu G Albert Istvan Patterson Andrew D Gonzalez Frank J | 2015 | Journal of Clinical Investigation2015,,1: | 1 |
| 6 | Deconvolutional artificial-neural-network framework for subfilter-scale models of compressible turbulence显示文摘We establish a deconvolutional artificial-neural-network(D-ANN)approach in large-eddy simulation(LES)of compressible turbulent flow.Filtered variables in the neighboring locations are taken as the inputs of D-ANN to recover original(unfiltered)variables,including density,momentum and pressure.The scale-similarity form is adopted to reconstruct subfilter-scale(SFS)terms.The proposed D-ANN models can give better a priori predictions of the sub-filter stress and heat flux than the classical approximate-deconvolution method(ADM)and the velocity-gradient model(VGM).The predicted SFS terms with the D-ANN models have correlation coefficients larger than 98.4%and relative errors smaller than 18%.In the a posteriori analysis,the D-ANN model compares against the implicit LES(ILES),the dynamic-Smagorinsky model(DSM),and the dynamic-mixed model(DMM).The D-ANN model predicts better than these classical models for velocity spectra,statistical properties of SFS kinetic energy flux and velocity increments.The turbulence statistics and transient velocity divergence are also accurately reconstructed.The type of explicit filter and the impact of compressibility do not significantly affect a posteriori accuracy of the D-ANN model.Results showthat the proposed D-ANN approach has a great potential in developing highly accurate SFS models for large-eddy simulation of complex compressible turbulent flow. | Zelong Yuan Yunpeng Wang Chenyue Xie Jianchun Wang | 2021 | Acta Mechanica Sinica2021,37,12: | 1 |
| 7 | USP22 promotes the G1/S phase transition by upregulating FoxM1 expressionvia β-catenin nuclear localization and is associated with poor prognosis in stageII pancreatic ductal adenocarcinoma显示文摘 | Zhen Ning Aman Wang Jinxiao Liang Yunpeng Xie Jiwei Liu Lu Feng Qiu Yan Zhongyu Wang | 2014 | International Journal of Oncology2014,,4: | 1 |
| 8 | USP22 promotes epithelial-mesenchymal transition via the FAK pathwayin pancreatic cancer cells显示文摘 | Zhen Ning Aman Wang Jinxiao Liang Yunpeng Xie Jiwei Liu Qiu Yan Zhongyu Wang | 2014 | Oncology Reports2014,,4: | 1 |
| 9 | Tunnel elasticity enhancement effect of 3D submicron ceramics(A_(l)2O_(3),TiO_(2),ZrO_(2)) fiber on polydimethylsiloxane (PDMS)显示文摘Some polymers are flexible,foldable,and wearable.Structural-functional composite is fabricated by adding inorganic fillers with functional properties.Up to date,compared with the polymer matrix,the composite prepared by polymer-inorganic fillers has lower flexibility,higher brittleness,and higher modulus of elasticity.In this paper,three-dimensional (3D) net-shaped submicron α-Al_(2)O_(3),orthorhombic ZrO_(2),and rutile TiO_(2) fiber were fabricated by solution blowing spinning on a large scale.On the contrary,the elastic modulus (E) of the composite prepared by this 3D ceramic fiber was greatly reduced,and the flexibility of the composite was higher than that of the polymer matrix.When the strain was 75%,the E of the 3D net-shaped Al_(2)O_(3) fiber-polydimethylsiloxane(PDMS) composite was 20% lower than that of PDMS.When the strain was 78%,the E of the 3D net-shaped TiO_(2) fiber-PDMS and 3D net-shaped ZrO_(2) fiber-PDMS composites decreased by 20% and 25%,respectively.This abnormal effect,namely the tunnel elastic enhancement effect,has great practical significance.In all-solid-state lithium-ion batteries,the composite inhibits lithium dendrite growth and the 3D inorganic network contributes to lithium ion transport.It is possible to promote the industrial production of low-cost and large-scale flexible solid-state lithium-ion batteries and it can enhance the energy storage density of energy storage materials.This novel idea also has bright prospects in flexible electronic materials. | Yuxiu HAO Junwei XIE Bingqing XU Bingkun HU Yunpeng ZHENG Yang SHEN | 2021 | Journal of Advanced Ceramics2021,10,3: | 1 |
| 10 | Resveratrol activation of SIRT1/MFN2 can improve mitochondria function,alleviating doxorubicin-induced myocardial injury显示文摘Background Doxorubicin is a widely used cytotoxic chemotherapy agent for treating different malignancies.However,its use is associated with dose-dependent cardiotoxicity,causing irreversible myocardial damage and significantly reducing the patient's quality of life and survival.In this study,an animal model of doxorubicin-induced cardiomyopathy was used to investigate the pathogenesis of doxorubicin-induced myocardial injury.This study also investigated a possible treatment strategy for alleviating myocardial injury through resveratrol therapy in vitro.Methods Adult male C57BL/6J mice were randomly divided into a control group and a doxorubicin group.Body weight,echocardiography,surface electrocardiogram,and myocardial histomorphology were measured.The mechanisms of doxorubicin cardiotoxicity in H9c2 cell lines were explored by comparing three groups(phosphate-buffered saline,doxorubicin,and doxorubicin with resveratrol).Results Compared to the control group,the doxorubicin group showed a lower body weight and higher systolic arterial pressure,associated with reduced left ventricular ejection fraction and left ventricular fractional shortening,prolonged PR interval,and QT interval.These abnormalities were associated with vacuolation and increased disorder in the mitochondria of cardiomyocytes,increased protein expression levels of α-smooth muscle actin and caspase 3,and reduced protein expression levels of Mitofusin2(MFN2)and Sirtuin1(SIRT1).Compared to the doxorubicin group,doxorubicin+resveratrol treatment reduced caspase 3 and manganese superoxide dismutase,and increased MFN2 and SIRT1 expression levels.Conclusion Doxorubicin toxicity leads to abnormal mitochondrial morphology and dysfunction in cardiomyocytes and induces apoptosis by interfering with mitochondrial fusion.Resveratrol ameliorates doxorubicin-induced cardiotoxicity by activating SIRT1/MFN2 to improve mitochondria function. | Qingling Zhang Yunpeng Zhang Bingxin Xie Daiqi Liu Yueying Wang Zandong Zhou Yue Zhang Emma King Gary Tse Tong Liu | 2023 | Cancer Innovation2023,2,4: | 1 |
| 11 | An integrated review of automation and robotic technologies for structural prefabrication and construction显示文摘Building construction has developed from the use of primitive tools to that of machinery,with a tendency toward automation.Automation of processes and robotics can improve efficiency,accuracy and safety in construction.On the other hand,structural prefabrication for construction is increasingly being adopted worldwide to enhance productivity and to alleviate the environmental impact of conventional construction processes.The combination and application of automation and prefabrication technologies may therefore introduce new developments to the construction industry.This paper provides a comprehensive review of the use of automation technology for structural prefabrication and construction,including recent developments,challenges and future trends.Five stages following the sequence of construction are proposed:design,construction management,robotic manufacturing,autonomous transportation and automatic structural assembly.The paper concludes that the widespread use of automation technology is preferable to structural prefabrication for construction,and that the design for robotic construction introduced through connection innovations may be beneficial as a means of avoiding complex operations and thus improving the efficiency of robotic assembly processes. | Cheav Por Chea Yu Bai Xuebei Pan Mehrdad Arashpour Yunpeng Xie | 2020 | Transportation Safety and Environment2020,2,2: | 0 |
| 12 | Genesis and metallogenic characteristic of Dongnan Cu–Mo deposit associated granitoids:LA-ICP-MS zircon U–Pb dating and isotope constraint from Zijinshan ore field in southeastern China显示文摘The Dongnan Cu–Mo deposit,located in the southeast of the Zijinshan ore field(the largest porphyry–epithermal system in Southeast China),represents the complex magmatic and metallogenesis events in the region.The petrogenesis and metallogenesis of granitoids from the deposit are not determined,especially the interactions between ore-bearing(granodiorite porphyry)and barren samples(granodiorite and diorite).In the paper,the whole rock geochemical features shared a similar affinity to the middle-lower content and revealed that they derived from partial melting of the Cathaysian basement with the contribution of mantle materials,even represented that they generated in the plate subduction;LA-ICP-MS zircon U–Pb ages show that these granodiorites,granodioritic porphyry and diorite,were generated during 114–103 Ma.The ore-bearing samples mostly presented ε_(Hf)(t)of negative values(peak value is-4 to-3)with old two-stage Hf model ages(t_(DM)^(2))(peak value is 1.10–1.15 Ga),while the barren sample showed slightly negative ε_(Hf)(t)(peak value is-1 to 0)values with young t_(DM)^(2)(peak value is 1.00–1.05 Ga).The value of zircon Ce^(4+)/Ce^(3+)ratio mostly higher than 450 was first verified for the ore-bearing samples in the Dongnan Cu–Mo deposit,and the values of ore-bearing were found to be higher than those from the barren,which suggests that the ore-bearing formed in more oxidized parental magma with higher oxygen fugacity.Based on the geochemical characteristic of the element and isotope,we concluded that the Early Cretaceous multiphases magmatic activities,low melting temperature and low pressure of pluton,and high oxygen fugacity of zircon,were the favorable conditions for metallogenesis of Dongnan Cu–Mo deposit. | Qifeng Xie Mingguo Zhai Yuanfeng Cai Yunpeng Dong Hong Zhang Aifang Xiao | 2023 | Acta Geochimica2023,42,2: | 0 |
| 13 | Relation Between Sintering Reactivity of Matrix and Thermal Shock Resistance of Ultra-low Cement Bonded Corundum-spinel Castables for Fired Purging Plugs显示文摘Purging plugs installed in the bottom of steel ladles are widely used for the secondary refining of high quality steel grades. The dynamic service conditions and temperature gradients caused by the cold inert gas blown through the plug during stirring create a strong thermal shock impact on the materials. This can affect its service life and restrict the safety and efficiency of steel making if the plug fails during use. In this work,the influence of the particle size distribution( PSD) and amount of reactive alumina on the sintering behavior of ultra-low cement bonded corundum-spinel based castables was investigated on lab scale. The relationship between sintering reactivity of matrix and thermal shock resistance of castables was evaluated in detail. Results show that the sintering of castables can be intensified by using finer reactive alumina. However, excessive sintering of the castable through finer reactive alumina is negative for thermal shock resistance. The microstructure characterization reveals that castables with more intense sintering show denser matrix structure,which is less effective inhampering crack propagation and therefore results in decline of their thermal shock resistance. | ZHANG Ju LONG Bin ZHOU Yunpeng Andreas BUHR WANG Feng CUI Qingyang XIE Guofeng DING Dafei JIA Quanli YE Guotian | 2018 | China's Refractories2018,27,4: | 0 |
| 14 | A controlled random gene perturbation method identifies ARPC1B gene as a key regulator of cancer metastasis显示文摘The discovery of clinically useful targets to treat specific pathological conditions can provide novel therapeutic approaches.To unbiasedly identify key genes related to tumor metastasis,we developed a random gene perturbation method using a piggyBac transposon system under the control of a doxycycline regulated promoter.Using this random gene perturbation method and utilizing a mouse model of metastatic pancreatic cancer,we identified genes dysregulated in metastasized cells from a random mutagenesis library after multiple rounds of in vivo selection.Analysis of these metastasized clones revealed the downregulation of ARPC1B gene.Our further mechanistic studies revealed that ARPC1B gene and its closely related gene ARPC1A worked in a regulatory loop to control tumor metastasis.These findings validate that piggyBac transposon mediated random gene perturbation is a powerful tool to investigate the functional relevance of novel genes and the ARPC1A/B axis is a potential key regulator of tumor metastasis. | De Chang Hongzhen Du Xiaowei Chen Xiaocui Bian Wenjia Tian Jing Shen Yiju Wei Yunpeng Jiang Charles Dela Cruz Lixin Xie Lokesh Sharma Kailong Li | 2023 | Genes & Diseases2023,10,3: | 0 |
| 15 | Network Function Virtualization Technology:Progress and Standardization显示文摘Network innovation and business transformation are both necessary for telecom operators to adapt to new situations,but operatorsface challenges in terms of network bearer complexity,business centralization,and IT/CT integration.Network function virtualiza-tion(NFV)may inspire new development ideas,but many doubts still exist within industry,especially about how to introduceNFV into an operator’s network.This article describes the latest progress in NFV standardization,NFV requirements and hottechnology issues,and typical NFV applications in an operator networks. | Huiling Zhao Yunpeng Xie Fan Shi | 2014 | ZTE Communications2014,12,2: | 0 |
| 16 | Crystallographic Characterization of Lu_(2)O@C_(s)(6)-C_(82)and Er_(2)O@C_(s)(6)-C_(82):The Role of Metal Species on Cluster Configuration显示文摘Comprehensive Summary Intramolecular interactions are fundamental for the unique structures and outstanding properties of metallofullerenes.However,how the internal metal species interplay with the cluster configuration inside oxide clusterfullerenes remains poorly understood.Herein,we successfully captured two oxide clusterfullerenes with different metals,namely,Lu_(2)O@C_(82)and Er_(2)O@C_(82),to elucidate the role of metal species in tuning cluster configuration.The two molecules have been fully characterized by mass spectrometry,Vis-NIR absorption spectroscopy,cyclic voltammetry,and single-crystal X-ray diffraction. | Pengwei Yu Haocheng Mei Shuaifeng Hu Changwang Pan Wangqiang Shen Pengyuan Yu Kun Guo Yunpeng Xie Takeshi Akasaka Lipiao Bao Xing Lu | 2023 | Chinese Journal of Chemistry2023,41,16: | 0 |
| 17 | A Crystal Plasticity Model with Irradiation Effect for the Mechanical Behavior of FCC Metals显示文摘In this paper,a crystal plasticity model considering the irradiation effect based on the thermal activation theory is established.The evolutions of screw dislocations,edge dislocations,and stacking fault tetrahedrals(SFTs)(induced by irradiation)are included into the model.The interactions between dislocations and irradiation-induced SFTs are also considered.The constitutive model is numerically implemented on the ABAQUS platform through UMAT subroutine and applied to study the irradiation effect on the mechanical behavior of pure copper.The mechanical properties of single and polycrystalline copper are studied,and the simulation results show that the constitutive model can properly predict the mechanical behavior of irradiated pure copper.Especially for polycrystalline copper,the simulation results are in good agreement with the experimental data. | Jnnfeng Nie Yunpeng Liu Pandong Lin Qihao Xie Zhanli Liu | 2019 | Acta Mechanica Solida Sinica2019,32,6: | 0 |
| 18 | Comparison of protective effects of electroacupuncture and moxibustion at Zusanli(ST 36)on perinatal nicotine exposure-induced lung phenotype in rat offspring显示文摘Objective:To compare the effects of electroacupuncture(EA)and moxibustion at Zusanli(ST 36)on the lung phenotype of rat offspring exposed to nicotine during the perinatal period.Methods:Pregnant Sprague-Dawley rats were randomly divided into 4 groups:the control group(saline only),the model group(nicotine only),the EA group(nicotine+EA at ST 36 acupoints bilaterally),and the moxibustion group(nicotine+moxibustion at ST 36 acupoints bilaterally).n=6 rats per group.On postnatal day 21,the body weight,lung weight,and pulmonary function were determined and lung morphometry was performed.Peroxisome proliferator-activated receptor gamma andβ-catenin levels in the lung tissue of offspring were also determined.Results:Perinatal nicotine exposure(PNE)results in decreased body and lung weights of offspring rats,abnormal lung tissue morphology,and significantly altered pulmonary function,showing an increase in total airway resistance and a decrease in tidal volume,minute ventilation,total airway compliance,and peak expiratory flow.Bilateral EA at ST 36 acupoints could block all of these perinatal nicotine-induced effects.Although moxibustion also had protective effects in nicotine-induced offspring lungs,some of these effects did not reach statistical significance,e.g.,protection against the upregulation ofβ-catenin,the downregulation of PPARγsignaling,and the increase in peak expiratory flow.Conclusion:Maternal EA at ST 36 blocked the PNE-induced changes in key developmental signaling pathways,prevented the PNE-induced changes in lung morphology,and protected pulmonary function.Moxibustion at ST 36 showed similar but weaker protective effects against the PNE-induced changes in the exposed offspring.It is important to note that the mechanism underlying the protective effects of moxibustion at ST 36 may be different from those of EA at ST 36,and further research is needed to understand these differences. | Yunpeng Ge Yitian Liu Guozhen Zhao Reiko Sakurai Yana Xie Tianyu Shi Yang Fang Jiajia Wang Virender K.Rehan Bo Ji | 2023 | Journal of Traditional Chinese Medical Sciences2023,10,3: | 0 |
| 19 | Dynamic nonlinear algebraic models with scale-similarity dynamic procedure for large-eddy simulation of turbulence显示文摘A dynamic nonlinear algebraic model with scale-similarity dynamic procedure(DNAM-SSD)is proposed for subgrid-scale(SGS)stress in large-eddy simulation of turbulence.The model coefficients of the DNAM-SSD model are adaptively calculated through the scale-similarity relation,which greatly simplifies the conventional Germano-identity based dynamic procedure(GID).The a priori study shows that the DNAM-SSD model predicts the SGS stress considerably better than the conventional velocity gradient model(VGM),dynamic Smagorinsky model(DSM),dynamic mixed model(DMM)and DNAM-GID model at a variety of filter widths ranging from inertial to viscous ranges.The correlation coefficients of the SGS stress predicted by the DNAM-SSD model can be larger than 95%with the relative errors lower than 30%.In the a posteriori testings of LES,the DNAM-SSD model outperforms the implicit LES(ILES),DSM,DMM and DNAM-GID models without increasing computational costs,which only takes up half the time of the DNAM-GID model.The DNAM-SSD model accurately predicts plenty of turbulent statistics and instantaneous spatial structures in reasonable agreement with the filtered DNS data.These results indicate that the current DNAM-SSD model is attractive for the development of highly accurate SGS models for LES of turbulence. | Zelong Yuan Yunpeng Wang Chenyue Xie Jianchun Wang | 2022 | Advances in Aerodynamics2022,4,1: | 0 |
| 20 | Critical review and functional safety of a battery management system for large‑scale lithium‑ion battery pack technologies显示文摘The battery management system(BMS)is the main safeguard of a battery system for electric propulsion and machine electrifcation.It is tasked to ensure reliable and safe operation of battery cells connected to provide high currents at high voltage levels.In addition to efectively monitoring all the electrical parameters of a battery pack system,such as the voltage,current,and temperature,the BMS is also used to improve the battery performance with proper safety measures within the system.With growing acceptance of lithium-ion batteries,major industry sectors such as the automotive,renewable energy,manufacturing,construction,and even some in the mining industry have brought forward the mass transition from fossil fuel dependency to electric powered machinery and redefned the world of energy storage.Hence,the functional safety considerations,which are those relating to automatic protection,in battery management for battery pack technologies are particularly important to ensure that the overall electrical system,regardless of whether it is for electric transportation or stationary energy storage,is in accordance with high standards of safety,reliability,and quality.If the system or product fails to meet functional and other safety requirements on account of faulty design or a sequence of failure events,then the environment,people,and property could be endangered.This paper analyzed the details of BMS for electric transportation and large-scale energy storage systems,particularly in areas concerned with hazardous environment.The analysis covers the aspect of functional safety that applies to BMS and is in accordance with the relevant industrial standards.A comprehensive evaluation of the components,architecture,risk reduction techniques,and failure mode analysis applicable to BMS operation was also presented.The article further provided recommendations on safety design and performance optimization in relation to the overall BMS integration. | K.W.See Guofa Wang Yong Zhang Yunpeng Wang Lingyu Meng Xinyu Gu Neng Zhang K.C.Lim L.Zhao Bin Xie | 2022 | International Journal of Coal Science & Technology2022,9,3: | 0 |