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| 1 | Optimization of groove texture profile to improve hydrodynamic lubrication performance:Theory and experiments显示文摘It is well known that groove texture with a careful design can be used to enhance the load‐carrying capacity of oil film under the conditions of hydrodynamic lubrication.In this study,a general parametric model was developed,and agenetic algorithm‐sequential quadratic programming hybrid method was adopted to obtain the global‐optimum profile of the groove texture.The optimized profiles at different rotating speeds are all chevrons.The numerical analysis results verified the effect of the optimization.In addition to the numerical optimization,experiments were conducted to validate the superiority of the optimized results.The experimental results show that the optimized groove texture can efficiently reduce the coefficient of friction(COF)and the temperature rise of the specimen.In particular,the optimized groove textures can achieve stable ultra‐low COF values(COF<0.01)under certain conditions. | Wei WANG Yongyong HE Jun ZHAO Junyuan MAO Yutong HU Jianbin LUO | 2020 | Friction2020，8，1： | 13 |
| 2 | A Novel Artificial Neuron-Like Gas Sensor Constructed from CuS Quantum Dots/Bi2S3 Nanosheets显示文摘Real-time rapid detection of toxic gases at room temperature is particularly important for public health and environmental monitoring.Gas sensors based on conventional bulk materials often suffer from their poor surface-sensitive sites,leading to a very low gas adsorption ability.Moreover,the charge transportation efficiency is usually inhibited by the low defect density of surface-sensitive area than that in the interior.In this work,a gas sensing structure model based on CuS quantum dots/Bi_(2)S_(3) nanosheets(CuS QDs/Bi_(2)S_(3) NSs)inspired by artificial neuron network is constructed.Simulation analysis by density functional calculation revealed that CuS QDs and Bi_(2)S_(3) NSs can be used as the main adsorption sites and charge transport pathways,respectively.Thus,the high-sensitivity sensing of NO_(2) can be realized by designing the artificial neuron-like sensor.The experimental results showed that the CuS QDs with a size of about 8 nm are highly adsorbable,which can enhance the NO_(2) sensitivity due to the rich sensitive sites and quantum size effect.The Bi_(2)S_(3) NSs can be used as a charge transfer network channel to achieve efficient charge collection and transmission.The neuron-like sensor that simulates biological smell shows a significantly enhanced response value(3.4),excellent responsiveness(18 s)and recovery rate(338 s),low theoretical detection limit of 78 ppb,and excellent selectivity for NO_(2).Furthermore,the developed wearable device can also realize the visual detection of NO2 through real-time signal changes. | Xinwei Chen Tao Wang Jia Shi Wen Lv Yutong Han Min Zeng Jianhua Yang Nantao Hu Yanjie Su Hao Wei Zhihua Zhou Zhi Yang Yafei Zhang | 2022 | Nano-Micro Letters2022，14，1： | 3 |
| 3 | Optimization of Grain Boundary Character Distribution in Fe-18Cr-18Mn-0.63N High-Nitrogen Austenitic Stainless Steel显示文摘Grain boundary engineering(GBE)is a practice of improving resistance to grain boundary failure of the material through increasing the proportion of low Σ coincidence site lattice(CSL)grain boundaries(special grain boundaries)in the grain boundary character distribution(GBCD).The GBCD in a cold rolled and annealed Fe-18Cr-18Mn-0.63N high-nitrogen austenitic stainless steel was analyzed by electron back scatter difraction(EBSD).The results show that the optimization process of GBE in the conventional austenitic stainless steel cannot be well applied to this high-nitrogen austenitic stainless steel.The percentage of lowΣCSL grain boundaries could increase from 47.3%for the solid solution treated high-nitrogen austenitic stainless steel specimen to 82.0%for the specimen after 5%cold rolling reduction and then annealing at 1423 K for 10 min.These special boundaries of high proportion efectively interrupt the connectivity of conventional high angle grain boundary network and thus achieve the GBCD optimization for the high-nitrogen austenitic stainless steel. | Feng SHI Xiaowu LI Yutong HU Chuan SU Chunming LIU | 2013 | Acta Metallurgica Sinica(English Letters)2013，26，5： | 2 |
| 4 | Multifunctional tubular carbon nanofibers/polyurethane electromagnetic wave absorber with room-temperature self-healing and recyclable performance显示文摘Incorporating self-healing and recyclable capabilities into microwave absorbing materials is expected to facilitate the life extension,cost reduction,and performance stability,thereby meeting the practical applications.In this research,a recycling and room-temperature self-healing electromagnetic wave(EMW)absorber is designed,in which linear polyurethane cross-linked by aromatic disulfide bonds is used as healable matrix,and tubular carbon nanofibers(TCNFs)are employed to attenuate microwave.The resultant composites with a TCNFs content of 7 wt.%harvest a minimum reflection loss(RLmin)of−39.0 dB and an effective absorption bandwidth(EAB)of 2.9 GHz at a matching thickness of 4.0 mm.Driven by the reversible dynamic bonds including hydrogen bonds and aromatic disulfide bonds,the high healing efficiency of 88.7%at 25°C and 93.2%at 60°C is presented.Impressively,even after three repairing cycles at room temperature,a healable efficiency of 86.4%is acquired,and RLmin can still reach−39.1 dB at the same thickness,together with an EAB of 3.0 GHz.Additionally,the results of solvent recycling experiment manifest that the recycled specimen achieves the almost similar mechanical and microwave dissipation properties as original one.These attractive characteristics make the designed self-healing and recyclable composites promising for next-generation EMW consumption devices. | Shuai Kang Shiya Qiao Yutong Cao Zuming Hu Na Li Junrong Yu Yan Wang | 2023 | Nano Research2023，16，1： | 1 |
| 5 | A porous hydrogel scaffold mimicking the extracellular matrix with swim bladder derived collagen for renal tissue regeneration显示文摘As a worldwide public health issue, chronic kidney disease still lacks of effective therapeutic approaches due to the challenges in conventional organ transplantation and dialysis. Renal tissue engineering offers an advantageous therapeutic or regenerative option over typical donor organ. However, despite the great progress of decellularized extracellular matrix based scaffold for the renal regeneration, several safety concerns and complex composition still remain to be addressed. Herein, the extracellular matrix-mimicking hydrogel scaffolds were developed through covalent and physical cross-linking between swim bladder-derived natural collagen(COL) and anti-fibrosis chondroitin sulfate(CS) derivatives.The biomimetic hydrogels showed proper mechanical property, excellent thermal stability and high biocompatibility both in vitro and in vivo, by altering the mass ratio of COL and CS. When implanted in partially nephrectomized rat model, the 1 COL/2CS scaffold enable it recruit more native kidney cells, reduce the tubular damage, and even induce the regeneration of renal tubular-like tissue and restore renal metabolic function more effectively comparing with the pure 2COL and 2CS scaffold. These results suggest that the biomimetic scaffold is a promising functional platform for treating renal diseases. | Heng Wu Rui Zhang Bianxiang Hu Yutong He Yuehang Zhang Liu Cai Leyu Wang Guobao Wang Honghao Hou Xiaozhong Qiu | 2021 | Chinese Chemical Letters2021，32，12： | 1 |
| 6 | Proton angular distribution research by a new angle-resolved proton energy spectrometer显示文摘The proton spectral and angular distributions simultaneously within the target normal direction and laser propagation direction by using an angle-resolved proton energy spectrometer are studied.For the protons generated in the interactions of 100 fs,800nm laser pulses with aluminum foil targets,the deviations of proton beam centers of different energies from the target normal direction towards the laser propagation direction are different.This is probably because of the toroidal magnetic fields generated at the rear target surface,which deflect protons transversely.As a result,protons in low energy range have large deviation angles,protons in middle energy range have the smallest deviation angles,while protons in high energy tail have large deviation angles. | SU LuNing ZHENG Yi LIU Meng HU ZhiDan WANG WeiMin YUAN XiaoHui XU MiaoHua SHENG ZhengMing SHEN ZhongWei FAN HaiTao LI YuTong MA JingLong LU Xin CHEN LiMing WANG ZhaoHua WEI ZhiYi ZHANG Jie | 2014 | Science China(Physics,Mechanics & Astronomy)2014，57，5： | 1 |
| 7 | Evidence base of randomized controlled trials and guideline recommendations of patent Traditional Chinese Medicines for uncomplicated acute lower respiratory tract infections in adults显示文摘OBJECTIVE:To compare clinical practice guideline recommendations on the use of oral patent Traditional Chinese Medicines(PTCMs) for uncomplicated acute lower respiratory tract infections(ALRTIs)in adults with the existing evidence using results of a systematic review of randomized controlled trials(RCTs).METHODS:A systematic review on RCTs and a systematic review of current guidelines on orally taken PTCMs for uncomplicated ALRTIs were performed.Pub Med,Cochrane Library,EMBASE and four Chinese databases were searched from inception to September 2016 for RCTs testing orally taken PTCMs for uncomplicated ALRTIs(excluding pneumonia).Two reviewers independently screened each study,extracted study data,and assessed risk of bias.Disagreements were resolved through discussion or by consultation with a third reviewer.Clinical practice guidelines for uncomplicated ALRTIs containing PTCM recommendations were identified and quality appraised.The quality of pooled evidence of the RCTs and the guidelines was assessed with GRADE and AGREE Ⅱ respectively.The consistency of the evidence base in RCTs and the guideline recommendations were then compared.RESULTS:For the systematic review of RCTs,4810 papers were identified,among which 29 RCTs(5093 patients) were included in the review.PTCMs compared to placebo increased the effective treatment rate of cough(3 trials,949 patients,risk ratio(RR) 2.50,1.16 to 5.43;low certainty);improved assessment of global health(3 trials,948 patients,RR1.70,1.44 to 2.01;low certainty);and increased the effective rate of specific symptom relief(1 trial,478 patients,RR 4.01,2.76 to 5.81;moderate certainty).21 trials(3432 patients) compared effects of different PTCMs.For the guideline evaluation,29 PTCMs were recommended for the use of uncomplicated ALRTIs,of which27 had no supportive evidence from RCTs.CONCLUSION:The evidence base of PTCMs for uncomplicated ALRTIs is weak and the guideline recommendations were based on almost no clinical trial evidence.Rigorous clinical research is urgently needed to inform the clinical use of these herbal medicines.Further training in evidence-based medicine methods for Traditional Chinese Medicine guideline developers is essential. | Xia Ruyu Hu Xiaoyang Wang Di Wang Ying Merlin Willcox Liu Jianping Michael Moore Andrew Flower Li Xun Lily Lai Hu Ruixue Wen Lingzi Zhang Lishan Wang Qi Fei Yutong | 2018 | Journal of Traditional Chinese Medicine2018，38，4： | 1 |
| 8 | Molecular mechanism of lycopene cyclases regulating carotenoids ratio in different branches during tea leaf and flower development显示文摘Carotenoids are essential components in tea quality, contributing to leaf color and aroma. However, little information about carotenoids in different tea cultivars and their biosynthesis regulation mechanism during leaf development is known. Here we analyzed carotenoids by HPLC in the buds and leaves of 113 tea cultivars harvested on the same day. By profile clustering, carotenoids were divided into five groups. Same group cultivars displayed divergence in the total content of carotenoids but a similar molar ratio. To figure out the molecular mechanisms of this phenomenon, we further characterized all functional lycopene cyclases, which are the branch point of the carotenoid biosynthesis pathway. Two β-lycopene cyclases(CsLCYB1 and CsLCYB2) and one ε-lycopene cyclase(CsLCYE1) were cloned. Subcellular localization analysis showed that all cloned CsLCYs were localized in plastids. Enzyme activity assays in E. coli indicated both CsLCYBs catalyzed lycopene into β-carotene, and CsLCYE1 produced δ-carotene and ε-carotene. We found CsLCYB1 and CsLCYE1 predominantly expressed in leaf, while CsLCYB2was mainly expressed during flowering stages. Suppression by antisense oligonucleotides reduced CsLCYB1 and CsLCYE1 transcripts and led to reduction of both β,β-branch and β,ε-branch carotenoids in leaf. The expression levels of CsLCYB1 showed a significant positive correlation withβ,β-branch carotenoids in leaf. Our study provides carotenoid profiles of different tea cultivars, which can assist tea producers in selecting cultivars of interest. Meanwhile, we proposed the molecular mechanism of carotenoids reflecting the tenderness of tea plant leaf from a metabolic flux perspective, and suggested lycopene cyclase that could be applied to the breeding of tea varieties with different branch carotenoids. | Anqi Peng Xiaoyan Tang Yingying Feng Yun Huang Jilai Cui Kai Tian Mengqian Lu Yifan Zhao Yuting Pan Sanjin Wang Yutong Hu Wei Zhao Chuankui Song Qiang Wang | 2023 | Horticultural Plant Journal2023，9，6： | 0 |
| 9 | HTDcr:a job execution framework for high-throughput computing on supercomputers显示文摘High-throughput computing(HTC)is a computing paradigm that aims to accomplish jobs by easily breaking them into smaller,independent components.However,it requires a large amount of computing power for a long time.Most existing HTC frameworks are job-oriented without support for coscheduling with hardware architecture and task-level execution.Also,most of the frameworks reach a limited scale,and their usability needs further improvement.Herein,we present HTDcr,a job execution framework for the HTC on supercomputers.This study aims to improve the throughput,task dispatching,and usability of the framework.In detail,the throughput optimizations include a sophisticated designed task management system,a hierarchical scheduler,and the co-optimization of the task-scheduling strategy with the application and hardware characteristics.The optimizations for usability include a programable execution workflow,mechanisms for more robust and reliable service qualities,and a fine-grained resource allocation system for the colocation of multiple jobs.According to our evaluations,HTDcr can achieve outstanding scalability and high throughput on large-scale clusters for the HTC workload.We evaluate HTDcr with several microbenchmarks and real-world applications on Tianhe-2 and Sunway TaihuLight to demonstrate its effects on existing design mechanisms.For instance,the task scheduling for two real-world applications integrated with the application and hardware characteristics achieves 1.7×and 1.9×speedups over the basic task-scheduling strategy. | Jiazhi JIANG Dan HUANG Hu CHEN Yutong LU Xiangke LIAO | 2024 | Science China(Information Sciences)2024，67，1： | 0 |
| 10 | Cardiac energy metabolism disorder mediated by energy substrate imbalance and mitochondrial damage upon tebuconazole exposure显示文摘Tebuconazole exposure has been described as an increasing hazard to human health.An increasing number of recent studies have shown a positive association between tebuconazole exposure and cardiovascular disease risk,which is characterized by the reduction of adenosine triphosphate(ATP)synthesis.However,researches on the damage of tebuconazole exposure to energy metabolism and the related molecular mechanisms are limited.In the present study,male C57BL/6 mice were treated with tebuconazole at different low concentrations for 4 weeks.The results indicated that tebuconazole could accumulate in the heart and further induce the decrease of ATP content in the mouse heart.Importantly,tebuconazole induced an obvious shift in substrate utilization of fatty acid and glucose by disrupting their corresponding transporters(GLUT1,GLUT4,CD36,FABP3 and FATP1)expression,and significantly repressed the expression of mitochondrial biogenesis(Gabpa and Tfam)and oxidative phosphorylation(CS,Ndufa4,Sdhb,Cox5a and Atp5b)related genes in a dosedependent manner.Further investigation revealed that these alterations were related to the IRS1/AKT and PPARγ/RXRαpathways.These findings contribute to a better understanding of triazole fungicide-induced cardiovascular disease by revealing the key indicators associated with this phenomenon. | Tingting Ku Jindong Hu Mengmeng Zhou Yuanyuan Xie Yutong Liu Xin Tan Lin Guo Guangke Li Nan Sang | 2024 | Journal of Environmental Sciences2024，，2： | 0 |
| 11 | Locally generalised multi-agent reinforcement learning for demand and capacity balancing with customised neural networks显示文摘Reinforcement Learning(RL)techniques are being studied to solve the Demand and Capacity Balancing(DCB)problems to fully exploit their computational performance.A locally gen-eralised Multi-Agent Reinforcement Learning(MARL)for real-world DCB problems is proposed.The proposed method can deploy trained agents directly to unseen scenarios in a specific Air Traffic Flow Management(ATFM)region to quickly obtain a satisfactory solution.In this method,agents of all flights in a scenario form a multi-agent decision-making system based on partial observation.The trained agent with the customised neural network can be deployed directly on the corresponding flight,allowing it to solve the DCB problem jointly.A cooperation coefficient is introduced in the reward function,which is used to adjust the agent’s cooperation preference in a multi-agent system,thereby controlling the distribution of flight delay time allocation.A multi-iteration mechanism is designed for the DCB decision-making framework to deal with problems arising from non-stationarity in MARL and to ensure that all hotspots are eliminated.Experiments based on large-scale high-complexity real-world scenarios are conducted to verify the effectiveness and efficiency of the method.From a statis-tical point of view,it is proven that the proposed method is generalised within the scope of the flights and sectors of interest,and its optimisation performance outperforms the standard computer-assisted slot allocation and state-of-the-art RL-based DCB methods.The sensitivity analysis preliminarily reveals the effect of the cooperation coefficient on delay time allocation. | Yutong CHEN Minghua HU Yan XU Lei YANG | 2023 | Chinese Journal of Aeronautics2023，36，4： | 0 |
| 12 | Recent advances in fluorinated polymers:synthesis and diverse applications显示文摘Fluorinated polymers exhibit a unique combination of attributes,including chemical inertness,low surface energy,exceptional weather resistance,and intriguing electrical properties.This mini review provides an overview of recent advancements in the research of fluorinated polymers,highlighting the development of synthetic strategies for novel fluorinated polymers and their diverse applications in various fields.Traditional fluorinated polyolefins can be modified through chemical methods to produce functional materials.Copolymerization of fluorinated olefins with non-fluorinated monomers effectively addresses synthesis challenges,yielding main-chain fluoro-containing polymers with specific functional groups.Additionally,recent studies have revealed that free radical(co)polymerization of fluorinated(meth)acrylate monomers leads to new fluorinated polymers with enhanced solubility,processability,and structural diversity.Capitalizing on these new synthetic strategies,a range of fluorinated polymer materials has been developed for a multitude of applications,including flexible electrodes,alternating current(AC)electroluminescent devices,energy storage capacitors,triboelectric nanogenerators,and lithium batteries.With their customized structures and excellent properties,fluorinated polymers hold significant promise to uncover more potential applications in the era of flexible and wearable electronics. | Yutong Chen Chuan Luo Faqi Hu Zhenkai Huang Kan Yue | 2023 | Science China Chemistry2023，66，12： | 0 |
| 13 | Image Reconstruction for ECT under Compressed Sensing Framework Based on an Overcomplete Dictionary显示文摘Electrical capacitance tomography(ECT)has great application potential inmultiphase processmonitoring,and its visualization results are of great significance for studying the changes in two-phase flow in closed environments.In this paper,compressed sensing(CS)theory based on dictionary learning is introduced to the inverse problem of ECT,and the K-SVD algorithm is used to learn the overcomplete dictionary to establish a nonlinear mapping between observed capacitance and sparse space.Because the trained overcomplete dictionary has the property to match few features of interest in the reconstructed image of ECT,it is not necessary to rely on the sparsity of coefficient vector to solve the nonlinear mapping as most algorithms based on CS theory.Two-phase flow distribution in a cylindrical pipe was modeled and simulated,and three variations without sparse constraint based on Landweber,Tikhonov,and Newton-Raphson algorithms were used to rapidly reconstruct a 2-D image. | Xuebin Qin Yutong Shen Jiachen Hu Mingqiao Li Peijiao Yang Chenchen Ji Xinlong Zhu | 2022 | Computer Modeling in Engineering & Sciences2022，，3： | 0 |
| 14 | Construction and features of somatology in 9-year Qihuang TCM experimental class显示文摘Nine-year Qihuang experimental class,which is characterized by nine-year direct Ph.D.,was first opened in 2011,which is an exploration of the way of cultivating high-end characteristic talents of Chinese medicine specialty in our University.Under the background of“quality revolution”in higher education,our University has put forward the cultivation idea of“traditional Chinese medicine+”and“+traditional Chinese medicine”according to the orientation of running a school.Based on this,we have taken the lead in the reform of the curriculum integration of normal body science based on form,tissue and function.From the thought to the practice of teaching reform,we have carried on the thorough exploration and the beneficial attempt to train the Chinese medicine high-end talented persons.Furthermore we have accumulated certain experience. | Wang Yuanyuan Sun Hongmei Li Jian Guo Jian Fei Yutong Guo Zhenyu Gai Cong Hu Die Zhang Yi | 2021 | 解剖学杂志2021，44，S01： | 0 |
| 15 | Microfluidic chemostatic bioreactor for high-throughput screening and sustainable co-harvesting of biomass and biodiesel in microalgae显示文摘As a renewable and sustainable source for energy,environment,and biomedical applications,microalgae and microalgal biodiesel have attracted great attention.However,their applications are confined due to the cost-efficiency of microalgal mass production.One-step strategy and continuous culturing systems could be solutions.However,current studies for optimization throughout microalgae-based biofuel production pipelines are generally derived from the batch culture process.Better tools are needed to study algal growth kinetics in continuous systems.A microfluidic chemostatic bioreactor was presented here,providing low-bioadhesive cultivations for algae in a cooperative environment of gas,nutrition,and temperature(GNT)involved with high throughput.The chip was used to mimic the continuous culture environment of bioreactors.It allowed simultaneously studying of 8×8 different chemostatic conditions on algal growth and oil production in parallel on a 7×7 cm^(2)footprint.On-chip experiments of batch and continuous cultures of Chlorella.sp.were performed to study growth and lipid accumulation under different nitrogen concentrations.The results demonstrated that microalgal cultures can be regulated to grow and accumulate lipids concurrently,thus enhancing lipid productivity in one step.The developed on-chip culturing condition screening,which was more suitable for continuous bioreactor,was achieved at a half shorter time,64-times higher throughput,and less reagent consumption.It could be used to establish chemostat cultures in continuous bioreactors which can dramatically accelerate the development of renewable and sustainable algal for CO_(2)fixation and biosynthesis and related systems for advanced sustainable energy,food,pharmacy,and agriculture with enormous social and ecological benefits. | Guoxia Zheng Yutong Cui Ling Lu Ming Guo Xuejun Hu Lin Wang Shuping Yu Shenxia Sun Yuancheng Li Xingcai Zhang Yunhua Wang | 2023 | Bioactive Materials2023，，7： | 0 |
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