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| 1 | CDR3δ-grafted γ9δ2T cells mediate effective antitumor reactivity显示文摘采纳房间转移治疗(幕) 被报导了压制成长肿瘤并且在动物模型克服肿瘤逃跑。作为一个候选人幕受动器, γ 9 δ 2T 房间能在 vitro 并且在 vivo 和显示被激活并且膨胀对 colorectal 的强壮的 antitumor 活动,肺,前列腺,卵巢、肾的房间癌。然而,获得 γ 的一个足够大的数字是困难的; δ为能克服癌症病人的有免疫力的镇压肿瘤微型环境的免疫疗法满足需要的 T 房间。在以前的研究,我们的实验室证实了那 γ 9 δ 2T 房间经由 CDR3δ 认出了肿瘤房间;γ 的区域; δ -T-cell 受体(TCR ) 。我们构造了导出的全身的人的外部血 mononuclear 房间(PBMC )γ 9 并且 δ CDR3 区域被卵巢的上皮的癌(OEC ) 在代替的 2 链导出 CDR3。我们转移了 CDR3δ -grafted γ 9 δ进外部血淋巴细胞(PBL ) 的 2TCR 修改了 γ 遗传上发展; 9 δ 2T 房间。在 vitro,研究显示出那这些 CDR3δ -grafted γ 9 δ 2T 房间能向肿瘤房间与肿瘤房间摘录和展览 cytotoxicity 在刺激以后生产 cytokines,包括人的 OEC 和颈的腺癌。CDR3δ -grafted γ 9 δ采纳地变成忍受一根人的 OEC 房间线的裸体老鼠的 2T 房间表明了重要 antitumor 效果。这些结果显示那 CDR3δ -grafted γ 9 δ 2T 房间可能是临床的肿瘤免疫疗法的候选人。 | Hui Zhao Xueyan Xi Lianxian Cui Wei He | 2012 | Cellular & Molecular Immunology2012，9，2： | 10 |
| 2 | Gut microbiome alterations and its link to corticosteroid resistance in immune thrombocytopenia显示文摘Quantitative metagenomic studies have linked the gut microbiota to autoimmune disorders.Here,we performed deep shotgun metagenomic sequencing of fecal samples from 99 immune thrombocytopenia(ITP)patients and 52 healthy controls.Dysbiosis in the gut microbiome of ITP was detected phylogenetically and functionally,and classifier based on species markers distinguished individuals with ITP from healthy controls.In particular,the abundance of Ruminococcus gnavus,Bifidobacterium longum and Akkermansia muciniphila was markedly increased in treatment-na?ve ITP patients,and the alterations of microbial species were correlated with clinical indices.Functionally,the secondary bile acid biosynthesis and flagellar assembly were depleted in the gut microbiota of ITP,which may contribute to the onset of ITP by affecting the immune system.Furthermore,we found that corticosteroid treatment affected the gut microbiome of ITP.Compared with corticosteroid-sensitive ITP patients,we identified that the corticosteroid-resistant ITP patients displayed a distinct gut microbiome,which was different from that of the treatment-na?ve ITP patients.Together,we provided support for the critical role of gut microbiota in the development of ITP and established a foundation for further research characterizing gut microbiota in relation to corticosteroid resistance of ITP. | Yanan Wang Fengqi Liu Gaochao Zhang Yan Su Xueyan Sun Qi Chen Chencong Wang Haixia Fu Yun He Xiaolu Zhu Xiao Liu Meng Lv Xiangyu Zhao Xiaosu Zhao Yueying Li Qianfei Wang Xiaojun Huang Xiaohui Zhang | 2021 | Science China(Life Sciences)2021，64，5： | 6 |
| 3 | Enhancing phytolith carbon sequestration in rice ecosystems through basalt powder amendment显示文摘由于大气的公司的快速的增加的全球温暖 < 潜水艇 class= “ a-plus-plus ” > 2 排放显著地正在影响世界经济和人的活动。在 phytoliths 的碳隐遁在陆上的生态系统被认为是高度稳定的碳水池机制减轻气候变化。然而,植物的反应到外部硅修正案的堵塞 phytolith 的碳(PhytOC ) 仍然保持不清楚。在这研究,我们调查了暗岩粉末(BP ) 的效果在米饭(Oryza sativa ) 的 phytolith 碳隐遁上的改正,一个 high-PhytOC 蓄电池。结果证明在米饭的 phytolith 和 PhytOC 的内容与 BP 改正增加了。在不同米饭植物部分的 PhytOC 生产流动更加变化了(0.0050.041 ? Mg 公司 < 潜水艇 class= “ a-plus-plus ” > 2 哈 < 啜 class= “ a-plus-plus ” > 1 一 < 啜 class= “ a-plus-plus ” > 有在鞘的最高的流动的 1 ), 。BP 改正能显著地在 150 在农田提高 phytolith 碳隐遁的流动 ?% 。如果 1.55 的全球米饭耕作 ?? 慣敲? | Fengshan Guo Zhaoliang Song Leigh Sullivan Hailong Wang Xueyan Liu Xudong Wang Zimin Li Yuying Zhao | 2015 | Science Bulletin2015，60，6： | 4 |
| 4 | Recent advances in Raman technology with applications in agriculture, food and biosystems: A review显示文摘Raman technology,which covers Raman spectroscopy(RS)and its various derivativemethods,has been widely applied in detection of various substances in agriculture,food and biosystems.This article reviews the recent advances in two mainstream Raman technologies as RS and SERS,including technical evolution,application and challenges,and spectral processing methods.Firstly,the origin,principle,defect,and development of RSwere introduced.Then,the current situation,existing problems,and development trend of RS and SERS were discussed in agriculture,food,and biosystems,such as adulteration recognition,plant diseases identification,farm chemicals detection,food additives determination,and toxins analysis.At last,the spectral analysis methods include noise reduction,feature extraction or variable selection,and modelingwere introduced in detail,which can realize the automatic and intelligent analysis of spectra without relying on professionals. | Shizhuang Weng Wenxiu Zhu Xueyan Zhang Hecai Yuan Ling Zheng Jinling Zhao Linsheng Huang Ping Han | 2019 | Artificial Intelligence in Agriculture2019，，3： | 3 |
| 5 | Chokeberry(Aronia melanocarpa)as a new functional food relationship with health:an overview显示文摘As a consumer product,black chokeberry(Aronia melanocarpa)is diffi cult to consume due to its pungent taste.It is mainly used in various food industries to produce a variety of juices,preserves,extracts,fruit teas and nutritional supplements.Traditionally,Potawatomi Native Americans used black chokeberry to treat colds,coughs and fever.It has been found to contain numerous active ingredients.Currently,there are many health and medical products that contain black chokeberry.The purpose of this review is to understand the nutritional benefi ts of black chokeberry and to explore its benefi cial effects on biological systems in vitro,thereby emphasizing its therapeutic prospects. | Yiwen Zhang Yingchun Zhao Xinglong Liu Xueyan Chen Chuanbo Ding Ling Dong Jinping Zhang Shuwen Sun Qiteng Ding Sadia Khatoom Zhiqiang Cheng Wencong Liu Liqian Shen Fengyan Xiao | 2021 | Journal of Future Foods2021，1，2： | 3 |
| 6 | Exponential stability of stochastic Markovian jump systems with time-varying and distributed delays显示文摘Dear editor,In the field of applied mathematics and control theory,the research on stochastic Markovian jump systems has attracted increasing attention in recent years.A few studies have been conducted on stochastic Markovian jump systems[1-6].Most previously conducted studies on stochastic Markovian jump systems investigate the discrete timevarying delay[4-6],whereas the distributed delay has not been given much attention owing to the difficulties involved in applying mathematical analysis. | Xueyan ZHAO Feiqi DENG Wenhua GAO | 2021 | Science China(Information Sciences)2021，64，10： | 3 |
| 7 | Hand preference during bimanual coordinated task in northern pig-tailed macaques Macaca leonina显示文摘 | Dapeng ZHAO Yuan WANG Xueyan WEI | 2016 | Current Zoology2016，62，4： | 3 |
| 8 | Stochastic stabilization using aperiodically sampled measurements显示文摘This paper addresses the stabilization problem of sector-bounded nonlinear systems with sampled measurements via discrete-time stochastic feedback control. Unlike the previous studies, the closed-loop system is modeled as an impulsive stochastic differential equation. By developing a quasi-periodic polynomial Lyapunov function and sampling-time-dependent Lyapunov function based methods, two sufficient conditions for almost sure exponential stability are derived in terms of differential matrix inequalities(DMIs) and linear matrix inequalities(LMIs). It is shown that the DMI-based conditions can be formulated as a sum of squares(SOSs). Moreover, the obtained results are adapted to sampled-data stochastic/deterministic systems. The numerical examples illustrate the theoretical results. | Shixian LUO Feiqi DENG Xueyan ZHAO Zhipei HU | 2019 | Science China(Information Sciences)2019，62，9： | 2 |
| 9 | Protein phosphatase PP4 is overexpressed in human breast and lung tumors显示文摘 | Bo Wang Ailian Zhao Lingling Sun Xueyan Zhong Jianing Zhong Haibo Wang Minhua Cai Jing Li Yi Xu Ji Liao Jianli Sang Dipanj an Chowdhury Gerd P Pfeifer Yun Yen Xingzhi Xu | 2008 | Cell Research2008，18，9： | 2 |
| 10 | Ascorbate peroxidase 1 confers resistance to southern corn leaf blight in maize显示文摘Southern corn leaf blight (SCLB), caused by Bipolarismaydis, is one of the most devastatingdiseases affecting maize production. However,only one SLCB resistance gene, conferring partialresistance, is currently known, underscoring theimportance of isolating new SCLB resistancerelatedgenes. Here, we performed a comparativeproteomic analysis and identified 258 proteinsshowing differential abundance during the maizeresponse to B. maydis. These proteins included anascorbate peroxidase (Zea mays ascorbate peroxidase1 (ZmAPX1)) encoded by a gene locatedwithin the mapping interval of a previously identifiedquantitative trait locus associated with SCLBresistance. ZmAPX1 overexpression resulted inlower H_(2)O_(2) accumulation and enhanced resistanceagainst B. maydis. Jasmonic acid (JA)contents and transcript levels for JA biosynthesisand responsive genes increased in ZmAPX1-overexpressing plants infected with B. maydis,whereas Zmapx1 mutants showed the oppositeeffects. We further determined that low levels of H_(2)O_(2) are accompanied by an accumulation of JAthat enhances SCLB resistance. These resultsdemonstrate that ZmAPX1 positively regulatesSCLB resistance by decreasing H_(2)O_(2) accumulationand activating the JA-mediated defensesignaling pathway. This study identified ZmAPX1as a potentially useful gene for increasing SCLBresistance. Furthermore, the generated datamay be relevant for clarifying the functions ofplant APXs. | Jinghua Zhang Xingmeng Jia Guan-Feng Wang Shijun Ma Shunxi Wang Qin Yang Xueyan Chen Yuqian Zhang Yajing Lyu Xiaoxu Wang Jiawei Shi Yangtao Zhao Yanhui Chen Liuji Wu | 2022 | Journal of Integrative Plant Biology2022，64，6： | 2 |
| 11 | Exposure to Emerging and Legacy Polyfluoroalkyl Substances in the Sixth Total Diet Study-China,2016-2019显示文摘Summary What is already known about this topic?Perfluoroalkyl substances(PFASs)are persistent organic pollutants,which have multi-organ toxicity and potential health risk to humans.What is added by this report?The most commonly detected PFASs in the Sixth China Total Diet Study(TDS)samples were perfluorooctanesulfonate(PFOS),perfluorooctanoic acid(PFOA),perfluoroundecanoic acid(PFUdA),perfluorodecanoic acid(PFDA),perfluorononanoic acid(PFNA),and 9-chlorohexadecafluoro-3-oxanonane-1-sulfonate(6:2 Cl-PFESA).The mean estimated weekly intakes(EWIs)of PFOA,PFOS,and 6:2 Cl-PFESA in the Sixth TDS were 2.17,2.72,and 2.75 ng/kg body weight per week,respectively.What are the implications for public health practice?The PFASs levels in some food category and dietary exposure still need to be continuously monitored,especially for 6:2 Cl-PFESA. | Yuxin Wang Xueyan Gao Jiaying Liu Bing Lyu Jingguang Li Yunfeng Zhao Yongning Wu | 2022 | China CDC weekly2022，4，9： | 2 |
| 12 | Variation analysis of growth traits of four poplar clones under different water and fertilizer management显示文摘To determine appropriate quantities of water and fertilizer required for early growth of hybrid poplar cuttings,we recorded the growth traits of four clones grown under four factors(irrigation and nitrogen,phosphorus,and potassium fertilizers),each with four levels,using an orthogonal experimental design.A logistic model was used to estimate growth in height.The growth curves for tree height were sigmoid,and the model R^2 values were greater than 0.9,which indicated that the fit was highly significant.ANOVA results for tree height and basal diameter indicated that all sources of variance showed significant differences(p<0.001).The average tree height and basal diameter for all the four clones under the different treatments ranged from 155.39 to 235.04 cm,and from 13.71 to 17.42 mm,respectively.A highly positive correlation between the extreme k value and tree height was observed,suggesting that the k value was an accurate estimation of tree height.For model parameters,the earliest average time point for the onset of the rapid growth period of poplar clones was 131 d,and the highest average increment in tree height during the rapid growth period was 138.78 cm.The highest average tree height for all clones under each factor was 219,210.51,200,and 201 cm when treated with either 1200 mL of water applied every third day,3 g of nitrogen,0 g of phosphorus,or 0 g of potassium,respectively.The most suitable treatment for the early growth of hybrid poplar cuttings,as suggested by the developed logistic model,was 1200 mL of water applied every third day and three applications of 1 g nitrogen(in the form of CH4N2O). | Ammar Khalil Mohamed Ahmed Luping Jiang Fang Wang Song Chen Xueyan Zhou Xiaona Pei Xiyang Zhao Guanzheng Qu | 2020 | Journal of Forestry Research2020，31，1： | 2 |
| 13 | Graphene metalens for particle nanotracking显示文摘Particle nanotracking(PNT)is highly desirable in lab-on-a-chip systems for flexible and convenient multiparameter measurement.An ultrathin flat lens is the preferred imaging device in such a system,with the advantage of high focusing performance and compactness.However,PNT using ultrathin flat lenses has not been demonstrated so far because PNT requires the clear knowledge of the relationship between the object and image in the imaging system.Such a relationship still remains elusive in ultrathin flat lens-based imaging systems because they operate based on diffraction rather than refraction.In this paper,we experimentally reveal the imaging relationship of a graphene metalens using nanohole arrays with micrometer spacing.The distance relationship between the object and image as well as the magnification ratio is acquired with nanometer accuracy.The measured imaging relationship agrees well with the theoretical prediction and is expected to be applicable to other ultrathin flat lenses based on the diffraction principle.By analyzing the high-resolution images from the graphene metalens using the imaging relationship,3D trajectories of particles with high position accuracy in PNT have been achieved.The revealed imaging relationship for metalenses is essential in designing different types of integrated optical systems,including digital cameras,microfluidic devices,virtual reality devices,telescopes,and eyeglasses,and thus will find broad applications. | XUEYAN LI SHIBIAO WEI GUIYUAN CAO HAN LIN YUEJIN ZHAO BAOHUA JIA | 2020 | Photonics Research2020，8，8： | 2 |
| 14 | A new perspective on fuzzy control of the stochastic T-S fuzzy systems with sampled-data显示文摘Dear editor,In the past several decades,stability analysis and synthesis of It?stochastic systems have gradually become the important areas of focus owing to their applications in many real-world systems,such as nuclear,thermal,chemical process,biological,socioeconomic,and immunological systems(1–5)In addition,nonlinearities exist in real plants,which always have more complex analyses than general linear systems.Moreover,the Takagi-Sugeno(TS)fuzzy systems,which are described by a set of fuzzy IF-THEN rules and local linear systems,are widely accepted as convenient tools to address nonlinearities in the systems[6,7]. | Shuqi LI Feiqi DENG Xueyan ZHAO | 2019 | Science China(Information Sciences)2019，62，10： | 2 |
| 15 | Enzymatic synthesis of L-lactic acid from carbon dioxide and ethanol with an inherent cofaetor regeneration cycle显示文摘 | Tong Xiaodong EI-Zahab Bilal Zhao Xueyan | 2011 | Biotechnology and Bioengineering2011，108，2： | 1 |
| 16 | Body Size but Not Food Size Determined Head Sexual Dimorphism in Rana kukunoris from the Tibetan Plateau显示文摘Sexual dimorphism between males and females is a common pattern observed in the natural world and has become one of the main focuses of evolutionary biology.Amphibian head size and shape are important factors that may influence food acquisition,but knowledge about the sexual differences between amphibian head size and shape is relatively scant.Here,intersexual differences in the head size and shape of Rana kukunoris,which is a high-elevation frog from the Qinghai-Tibet Plateau,were investigated.Significant differences were found in the head shape but not the head size between sexes.A significant correlation was also observed between prey size and head size.However,these correlations disappeared when individual body size was controlled,suggesting that body size but not food size was the main factor resulting in intersexual differences in head size/shape.The results suggested that food competition between sexes did not result in sexual dimorphism of head shape among these frogs. | Hongzhou CHEN Haifen QIN Zhenkun ZHAO Jiahong LIAO Yanfang WU Xueyan LIU Lichun JIANG Buddhi DAYANANDA Wei CHEN | 2023 | Asian Herpetological Research2023，14，2： | 1 |
| 17 | Analysisof dynamic characteristics for a rotor system with pedestallooseness显示文摘 | MA Hui ZHAO Xueyan TENG Yunnan | 2011 | Shock and Vibration2011，18，1： | 1 |
| 18 | Aggregation behavior of long - chain imidazolium ionic liquids in aqueous solution : Micellization and characterization of micelle microenvironment 显示文摘 | DONG BIN ZHAO XUEYAN ZHENG LIQIANG | 2008 | Colloids and Surfaces A: Physicochemical and Engineering Aspects2008，317，： | 1 |
| 19 | Effects of ec- centric phase difference between two discs on oil-film instability in a rotor-bearing system 显示文摘 | Ma Hui Li Hui Zhao Xueyan | 2013 | Mechanical Systems and Signal Processing2013，41，1： | 1 |
| 20 | Effects of eccentric phase difference between two discs on oil-film instability in a rotor–bearing system显示文摘 | Hui Ma Hui Li Xueyan Zhao Heqiang Niu Bangchun Wen | 2013 | Mechanical Systems and Signal Processing2013，，： | 1 |
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