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| 1 | Source apportionment for urban PM_(10) and PM_(2.5) in the Beijing area显示文摘Airborne particulate matter (PM2.5 and PM10) samples were collected at the Beijing Normal University sampling site in the urban area of Beijing, China in dry and wet seasons during 2001―2004. Concen-trations of 23 elements and 14 ions in particulate samples were determined by ICP-AES and IC, re-spectively. Source apportionment results derived from both Positive Matrix Factorization (PMF) and Chemical Mass Balance (CMB) models indicate that the major contributors of PM2.5 and PM10 in Beijing are: soil dust, fossil fuel combustion, vehicle exhausts, secondary particulate, biomass burning and some industrial sources. We have identified both regional common sources, such as vehicular emis-sions, particulate of secondary origin and biomass burning, as well as country-specific problems, such as sand storms and soil dust that should be addressed for effective air quality control. | ZHANG Wei GUO JingHua SUN YeLe YUAN Hui ZHUANG GuoShun ZHUANG YaHui HAO ZhengPing | 2007 | Chinese Science Bulletin2007，52，5： | 22 |
| 2 | Research on crystal growth and properties of a new nonlinear optical crystal:Bismuth borate BiB_3O_6显示文摘BiB3O6 (BIBO) single crystals with sizes of 44 mm × 24 mm × 10 mm and weight of 24.7 g have been successfully grown by the top-seeded method. In this note, the preparation of seed, the growth of crystal and some problems encountered are reported. The lattice parameters of BIBO are a =7.1203(7)A, b = 4.9948(7)A, c = 6.5077(7)A, β= 105.586(8) ', V=222.93(5)A3, which were determined by BRUKER-P4 four-circle diffractometer. BIBO is biaxial crystal and the relative orientation of (X, Y, Z) with regard to (a, b, c) is: X|| b, (Y, c) =47.2°, (Z, a) = 31.6°, determined by the X-ray analysis combined with polarized microscopy. The second-harmonic-generation (SHG) conversion efficiency of the sample for 1.064 μm light is up to 67.7%. We have also obtained the third harmonic generation (THG) of 1.064 μm, namely, 1.064 μm + 0.532 μn →0.355 μm. BIBO crystal is free of moisture and hygroscopy. | TENG Bing, WANG Jiyang, WANG Zhengping, JIANG Huaidong, SONG Renbo, LIU Hong, HU Xiaobo, LIU Yaogang, WEI Jingqian & SHAO ZongshuState Key Laboratory of Crystal Materials, Shandong University, Ji’nan 250100, China | 2001 | Chinese Science Bulletin2001，46，21： | 10 |
| 3 | A fundamental theorem for eco-environmental surface modelling and its applications显示文摘We propose a fundamental theorem for eco-environmental surface modelling(FTEEM) in order to apply it into the fields of ecology and environmental science more easily after the fundamental theorem for Earth’s surface system modeling(FTESM). The Beijing-Tianjin-Hebei(BTH) region is taken as a case area to conduct empirical studies of algorithms for spatial upscaling, spatial downscaling, spatial interpolation, data fusion and model-data assimilation, which are based on high accuracy surface modelling(HASM), corresponding with corollaries of FTEEM. The case studies demonstrate how eco-environmental surface modelling is substantially improved when both extrinsic and intrinsic information are used along with an appropriate method of HASM. Compared with classic algorithms, the HASM-based algorithm for spatial upscaling reduced the root-meansquare error of the BTH elevation surface by 9 m. The HASM-based algorithm for spatial downscaling reduced the relative error of future scenarios of annual mean temperature by 16%. The HASM-based algorithm for spatial interpolation reduced the relative error of change trend of annual mean precipitation by 0.2%. The HASM-based algorithm for data fusion reduced the relative error of change trend of annual mean temperature by 70%. The HASM-based algorithm for model-data assimilation reduced the relative error of carbon stocks by 40%. We propose five theoretical challenges and three application problems of HASM that need to be addressed to improve FTEEM. | Tianxiang YUE Na ZHAO Yu LIU Yifu WANG Bin ZHANG Zhengping DU Zemeng FAN Wenjiao SHI Chuanfa CHEN Mingwei ZHAO Dunjiang SONG Shihai WANG Yinjun SONG Changqing YAN Qiquan LI Xiaofang SUN Lili ZHANG Yongzhong TIAN Wei WANG Ying’an WANG Shengnan MA Hongsheng HUANG Yimin LU Qing WANG Chenliang WANG Yuzhu WANG Ming LU Wei ZHOU Yi LIU Xiaozhe YIN Zong WANG Zhengyi BAO Miaomiao ZHAO Yapeng ZHAO Yimeng JIAO Ufra NASEER Bin FAN Saibo LI Yang YANG John PWILSON | 2020 | Science China Earth Sciences2020，63，8： | 7 |
| 4 | Mild metal-organic-gel route for synthesis of stable sub-5-nm metal-organic framework nanocrystals显示文摘 | Yue Qi Chun-Ting He Juntao Lin Shuping Lin Jin Liu Jinghong Huang Wei Xue Guicheng Yu Hsiu-Yi Chao Yexiang Tong Zhengping Qiao | 2017 | Nano Research2017，10，11： | 3 |
| 5 | Fluorescent AIE dots encapsulated organically modified silica (ORMOSIL) nanoparticles for two-photon cellular imaging显示文摘2,3-Bis(4-(phenyl(4-(1,2,2-triphenylvinyl)phenyl)amino)phenyl) fumaronitrile (TPE-TPA-FN or TTF), which possesses aggregation-induced emission (AIE) characteristic, is doped in organically modified silica (ORMOSIL) nanoparticles. By increasing the weight ratio of TTF to the precursor of silica nanoparticles (the quantities of the precursors were kept the same), the fluorescence intensity of nanoparticles increased correspondingly, due to the formation of larger AIE dots in the cores of ORMOSIL nanoparticles. The fluorescent and biocompatible nanoprobes were then utilized for in vitro imaging of HeLa cells. Two-photon fluorescence microscopy clearly illustrated that the nanoparticles have the capacity of nucleus permeability, as well as cytoplasm staining towards tumor cells. Our experimental results may offer a promising method for fast and bright fluorescence imaging, as well as bio-molecule/drug delivery to cell nucleus. | ZHU ZhenFeng ZHAO XinYuan QIN Wei CHEN GuangDi QIAN Jun XU ZhengPing | 2013 | Science China Chemistry2013，56，9： | 3 |
| 6 | Synthesis,Conductivity and Photosensitivity of 2-D Conjugated Polymers of Metal-porphyrazine with Sulfur Bridges显示文摘Theporphyrazines(Pzs),i.e.tetraazaporphyrins(TAPs),andphthalocyanines(Pcs)andtheirpoly-mershavebeenreportedinmanypapers[1~13]... | Peng Zhenghe,\ Chen Xiaogui,\ Wang Zhengping,\ Wei Yihai,\ Qin Zibin College of Chemistry,Wuhan University, Wuhan 430072,China | 1998 | Wuhan University Journal of Natural Sciences1998，3，3： | 2 |
| 7 | Power-scalable sub-100-fs Tm laser at 2.08μm显示文摘We report on a power-scalable sub-100-fs laser in the 2-μm spectral range using a Tm;-doped‘mixed’(Lu,Sc);O;sesquioxide ceramic as an active medium.Pulses as short as 58 fs at 2076 nm with an average output power of 114 mW at a pulse repetition rate of approximately 82.9 MHz are generated by employing single-walled carbon nanotubes as a saturable absorber.A higher average power of 350 m W at 2075 nm is obtained at the expense of the pulse duration(65 fs).A maximum average power of 486 mW is achieved for a pulse duration of 98 fs and an optical conversion efficiency of 22.3%,representing the highest value ever reported from sub-100-fs mode-locked Tm lasers. | Li Wang Weidong Chen Yongguang Zhao Hanlin Yang Wei Jing Zhongben Pan Hui Huang Jiachen Liu Ji Eun Bae Fabian Rotermund Pavel Loiko Xavier Mateos Zhengping Wang Xinguang Xu Uwe Griebner Valentin Petrov | 2021 | High Power Laser Science and Engineering2021，9，4： | 1 |
| 8 | Chronic exposure to GSM 1800-MHz microwaves reduces excitatory synaptic activity in cultured hippocampal neurons显示文摘 | SHUJUN X U WEI NING ZHENGPING X U | 2006 | Neuroscience Letters2006，398，： | 1 |
| 9 | Chemiluminescent detection of DNA hybridization and single-nucleotide polymorphisms on a solid surface using target-primed rolling circle amplication 显示文摘 | LI Zhengping LI Wei CHENG Yongqiang | 2008 | The Analyst2008，133，： | 1 |
| 10 | ATP6V0d2 mediates leucine-induced mTORCI activation and polarization of macrophages显示文摘Dear Editor, mTORCI, as a center regulatory hub of metabolism, senses the cellular energy status, nutrition and extracellular stimuli and regulates cell growth, differentiation and functions of immune cells (Powell et al., 2012). Lysosomal localization of key signal comp orients is critical for mTORCI activati on: mTORCI activation requires co-localization of activated Rheb and mTORCI to the lysosome membrane (Buerger et al., 2006). Signals in eluding growth factors, cellular stresses and energy levels act on the disruption the formation of tuberous sclerosis complex (TSC) complex, comprised of TSC1, TSC2 and TBC1D7, which leads to the translocation and activation of Rheb on the lysosome membrane (Dibble et al., 2012). In response to nutrient levels, specifically the availability of amino acids and glucose (Efeyan et al., 2013), mTORCI is recruited to the lysosomal surface by Rag GTPases that are heterodimers of RagA or RagC bound to RagB or RagD. Multiple protein complexes have been implicated in regulation of mTORCI upon nutrient sensing including Ragulator, GATOR1, GATOR2, KICSTOR and vacuolar ATPases (Wolfson et al., 2017). Vacuolar ATPases are large multiple-protein complexes that acidify the lysosome and may mediate additional functions independent of their proton pump activity (Nishi and Forgac, 2002). | Pingfei Li Xiaofei Deng Jing Luo Yufei Chen Guoyu Bi Feili Gong Zhengping Wei Na Liu Huabin Li Arian Laurence Xiang-Ping Yang | 2019 | Protein & Cell2019，10，8： | 1 |
| 11 | Synthesis of MCM-48 with a high thermal and hydro-thermal stability显示文摘 | Hao Zhengping Hu Chun | 2005 | Materials Research Bulletin2005，40，10： | 1 |
| 12 | Impact of Stagger Angle Nonuniformity on Turbine Aerodynamic Performance显示文摘The assembling error may lead to variation in stagger angles,which would affect the aerodynamic performance of the turbine.To investigate this underlying effect,two parallel numerical experiments on two turbines with the same profile,but uniform and nonuniform vane stagger angle respectively,were conducted in both steady and unsteady methods.The results indicate that certain changes in the detailed flow field of the turbine occur when the stagger angles are nonuniform,further,the blade loading distribution of the vane and rotor become markedly different from that in uniform vane stagger angle situation.Then these consequences caused by nonuniformity mentioned above enhance the unsteadiness of the flow,finally,the aerodynamic performance changes dramatically.It also shows that,compared with steady simulation,the unsteady numerical simulation is necessary in this investigation. | Weihao Zhang Zhengping Zou Shangneng Pan Huoxing Liu Huoxing Liu Wei Li | 2010 | Journal of Thermal Science2010，19，5： | 0 |
| 13 | Effect of Alliance Orientation on Firm Performance: An Empirical Study on High-Technology Firms in China显示文摘在动态能力的看法和社会大写的理论之上基于,这篇论文在坚挺的性能上检验联盟取向的效果。假设被测试,数据在中国从 195 个高技术公司收集了。结果证明联盟取向在坚挺的性能上有重要、积极的效果。而且,市场精力在在联盟取向和坚挺的性能之间的关系上施加积极节制效果,而工艺的精力否定地节制关系。而且,关系资本部分调停一样的关系和坚挺的性能上的联盟取向和市场精力的相互作用效果。 | Zhengping Fu Wei Peng | 2012 | Frontiers of Business Research in China2012，6，3： | 0 |
| 14 | Disruption of the autism-related gene Pak1 causes stereocilia disorganization,hair cell loss,and deafness in mice显示文摘Several clinical studies have reported that hearing loss is correlated with autism in children.However,little is known about the underlying mechanism between hearing loss and autism.p21-activated kinases(PAKs)are a family of serine/threonine kinases that can be activated by multiple signaling molecules,particularly the Rho family of small GTPases.Previous studies have shown that Pak1 mutations are associated with autism.In the present study,we take advantage of Pak1 knockout(Pak1a/a)mice to investigate the role of PAK1 in hearing function.We find that PAK1 is highly expressed in the postnatal mouse cochlea and that PAK1 deficiency leads to hair cell(HC)apoptosis and severe hearing loss.Further investigation indicates that PAK1 deficiency downregulates the phosphorylation of cofilin and ezrin-radixin-moesin and the expression of b II-spectrin,which further decreases the HC synapse density in the basal turn of cochlea and disorganized the HC stereocilia in all three turns of cochlea in Pak1à/àmice.Overall,our work demonstrates that the autism-related gene Pak1 plays a crucial role in hearing function.As the first candidate gene linking autism and hearing loss,Pak1 may serve as a potential target for the clinical diagnosis of autism-related hearing loss. | Cheng Cheng Yilin Hou Zhonghong Zhang Yanfei Wang Ling Lu Liyan Zhang Pei Jiang Song Gao Qiaojun Fang Chengwen Zhu Junyan Gao Xufeng Liu Wei Xie Zhengping Jia Zhigang Xu Xia Gao Renjie Chai | 2021 | Journal of Genetics and Genomics2021，48，4： | 0 |
| 15 | Regulation of Social Memory by Lateral Entorhinal Cortical Projection to Dorsal Hippocampal CA2显示文摘Dear Editor,TSocial recognition memory is essential for proper conspecific interactions and its impairments are closely associated with many brain disorders,including autism,schizophrenia,and Alzheimer's disease[1-3].However,the mechanisms and neural circuits underlying social memory formation and retrieval are still unclear.Recent studies have revealed that several brain regions are involved in social memory formation,and the hippocampal dorsal CA2(dCA2)subregion appears to be its core locus[4,5]. | Rui Dang Yu Zhou Yue Zhang Die Liu Miao Wu An Liu Zhengping Jia Wei Xie | 2022 | Neuroscience Bulletin2022，38，3： | 0 |
| 16 | Morphological evolution and kinetic enhancement of Li_2Fe_xMn_(1-x)SiO_4/C cathodes for Li-ion battery显示文摘Li_2MnSiO_4-based cathode materials possess reasonable work potentials and high theoretical capacities,while the practical energy/power densities are constrained by their inferior kinetics of Li^+ diffusion.In this work,the Pmn2_1-structure Li_2Fe_xMn_(1-x)SiO_4/C materials were synthesized via a solvothermal method and evaluated as Liion cathode materials,with notable morphological evolutions and tunable crystallographic habits observed after solvothermal process.The Li_2Fe_(0.33)Mn_(0.67)SiO_4/C material delivers an initial reversible capacity of 250.2mAh g^(-1)at 0.1 C(~1.51 Li^+insertion/extraction,1 C=166 mA g^(-1)),excellent high-rate capability(52.2 mAh g^(-1)at 5 C),and good long-term cyclability(64.6%after 196 cycles at 2 C).The enhanced electrochemical properties are attributed to the boosted ion/electron transports induced by preferred morphological and structural characteristics of Li_2Fe_(0.33)Mn_(0.67)SiO_4/C. | Datong Zhang Zhengping Ding Shuai Zhao Ying Yang Yiming Feng Lei Xiao Ran Ji Libao Chen Weifeng Wei | 2018 | Progress in Natural Science:Materials International2018，28，5： | 0 |
| 17 | DAPK1(death associated protein kinase 1)mediates mTORC1 activation and antiviral activities in CD8^(+)T cells显示文摘Mechanistic target of rapamycin complex 1(mTORCt)regulates CD8^(+)T-cell differentiation and function.Despite the links between PI3K-AKT and mTORCI activation in CD8^(+)T cells,the molecular mechanism underlying mTORCI activation remains undear.Here,we show that both the kinase activity and the death domain of DAPK1 are required for maximal mTOR activation and CD8^(+)T-cell function.We found that TCR-induced activation of calcineurin activates DAPK1,which subsequently interacts with TSC2 via its death domain and phosphorylates TSC2 to mediate mTORCI activation.Furthermore,both the kinase domain and death domain of DAPK1 are required for CD8^(+)T-cell antiviral responses in an LCMV infection model.Together,our data reveal a novel mechanism of mTORCI activation that mediates optimal CD8^(+)T-cell function and antiviral activity. | Zhengping Wei Pingfei Li Ran He Huicheng Liu Na Liu Yu Xia Guoyu Bi Qiuyang Du Minghui Xia Lei Pei Jing Wang Guihua Wang Zhao-Hui Tang Xiang Cheng Huabin Li Zhuoya Li Lilin Ye Arian Laurence Youming Lu Xiang-Ping Yang | 2021 | Cellular & Molecular Immunology2021，18，1： | 0 |
| 18 | Fluorescent AIE dots encapsulated organically modified silica (ORMOSIL) nanoparticles for two-photon cellular imaging显示文摘2,3-Bis(4-(phenyl(4-(1,2,2-triphenylvinyl)phenyl)amino)phenyl)fumaronitrile(TPE-TPA-FN or TTF),which possesses aggregation-induced emission(AIE)characteristic,is doped in organically modified silica(ORMOSIL)nanoparticles.By increasing the weight ratio of TTF to the precursor of silica nanoparticles(the quantities of the precursors were kept the same),the fluorescence intensity of nanoparticles increased correspondingly,due to the formation of larger AIE dots in the cores of ORMOSIL nanoparticles.The fluorescent and biocompatible nanoprobes were then utilized for in vitro imaging of HeLa cells.Two-photon fluorescence microscopy clearly illustrated that the nanoparticles have the capacity of nucleus permeability,as well as cytoplasm staining towards tumor cells.Our experimental results may offer a promising method for fast and bright fluorescence imaging,as well as bio-molecule/drug delivery to cell nucleus. | ZHU ZhenFeng ZHAO XinYuan QIN Wei CHEN GuangDi QIAN Jun XU ZhengPing | 2013 | 中国科学:化学2013，43，9： | 0 |
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