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| 1 | Combined bone marrow stromal cells and oxiracetam treatments ameliorates acute cerebral ischemia/reperfusion injury through TRPC6显示文摘Ischemic stroke has become one of the leading causes of deaths and disabilities all over the world.In this study,we investigated the therapeutic effects of combined bone marrow stromal cells(BMSCs)and oxiracetam treatments on acute cerebral ischemia/reperfusion(I/R)injury.A rat model of middle cerebral artery occlusion(MCAO)followed by complete reperfusion,as well as a cortex neuron oxygen-glucose deprivation(OGD)model was established.When compared with BMSCs or oxiracetam monotherapy,combination therapy significantly improved functional restoration with decreased infarct volume in observed ischemic brain.We propose that it may occur through the transient receptor potential canonical(TRPC)6 neuron survival pathway.The increased expression of TRPC6 along with the reduction of neuronal cell death in the OGD cortex neurons and combination therapy group indicated that the TRPC6 neuron survival pathway plays an important role in the combined BMSCs and oxiracetam treatments.We further tested the activity of the calpain proteolytic system,and the results suggested that oxiracetam could protect the integrity of TRPC6 neuron survival pathway by inhibiting TRPC6 degradation.The protein levels of phospho-cAMP response element binding protein(p-CREB)were tested.It was found that BMSCs play a role in the activation of the TRPC6 pathway.Our study suggests that the TRPC6 neuron survival pathway plays a significant role in the protective effect of combined BMSCs and oxiracetam treatments on acute cerebral I/R injury.Combined therapy could inhibit the abnormal degradation of TRPC6 via decreasing the activity of calpain and increasing the activation of TRPC6 neuron survival pathway. | Jing Wang Ruohan Sun Zhenzhu Li Yujun Pan | 2019 | Acta Biochimica et Biophysica Sinica2019,51,8: | 17 |
| 2 | Nanostructured Bi2S3 encapsulated within three- dimensional N-doped graphene as active and flexible anodes for sodium-ion batteries显示文摘 | Chen Lu Zhenzhu Li Lianghao Yu Li Zhang Zhou Xia Tao Jiang Wanjian Yin Shixue Dou Zhongfan Liu Jingyu Sun | 2018 | Nano Research2018,11,9: | 9 |
| 3 | Effects of cotton field management practices on soil CO2 emission and C balance in an arid region of Northwest China显示文摘Changes in both soil organic C storage and soil respiration in farmland ecosystems may affect atmospheric CO2 concentration and global C cycle. The objective of this field experiment was to study the effects of three crop field management practices on soil CO2 emission and C balance in a cotton field in an arid region of Northwest China. The three management practices were irrigation methods(drip and flood), stubble managements(stubble-incorporated and stubble-removed) and fertilizer amendments(no fertilizer(CK), chicken manure(OM), inorganic N, P and K fertilizer(NPK), and inorganic fertilizer plus chicken manure(NPK+OM)). The results showed that within the C pool range, soil CO2 emission during the whole growing season was higher in the drip irrigation treatment than in the corresponding flood irrigation treatment, while soil organic C concentration was larger in the flood irrigation treatment than in the corresponding drip irrigation treatment. Furthermore, soil CO2 emission and organic C concentration were all higher in the stubble-incorporated treatment than in the corresponding stubble-removed treatment, and larger in the NPK+OM treatment than in the other three fertilizer amendments within the C pool range. The combination of flood irrigation, stubble incorporation and application of either NPK+OM or OM increased soil organic C concentration in the 0-60 cm soil depth. Calculation of net ecosystem productivity(NEP) under different management practices indicated that the combination of drip irrigation, stubble incorporation and NPK+OM increased the size of the C pool most, followed by the combination of drip irrigation, stubble incorporation and NPK. In conclusion, management practices have significant impacts on soil CO2 emission, organic C concentration and C balance in cotton fields. Consequently, appropriate management practices, such as the combination of drip irrigation, stubble incorporation, and either NPK+OM or NPK could increase soil C storage in cotton fields of Northwest China. | QianBing ZHANG Ling YANG ZhenZhu XU YaLi ZHANG HongHai LUO Jin WANG WangFeng ZHANG | 2014 | Journal of Arid Land2014,6,4: | 8 |
| 4 | Confining MOF-derived SnSe nanoplatelets in nitrogen-doped graphene cages via direct CVD for durable sodium ion storage显示文摘Tin-based compounds are deemed as suitable anode candidates affording promising sodium-ion storages for rechargeable batteries andhybrid capacitors.However,synergistically tailoring the electrical conductivity and structural stability of tin-based anodes to attain durablesodium-ion storages remains challenging to date for its practical applications.Herein,metal-organic framework(MOF)derived SnSe/C wrappedwithin nitrogen-doped graphene(NG@SnSe/C)is designed targeting durable sodium-ion storage.NG@SnSe/C possesses favorable electricalconductivity and structure stability due to the'inner'carbon framework from the MOF thermal treatment and'outer'graphitic cage from thedirect chemical vapor deposition synthesis.Consequently,NG@SnSe/C electrode can obtain a high reversible capacity of 650 mAh·g^-1 at 0.05 A·g^1,a favorable rate performance of 287.8 mAh·g^1 at 5 A·g^1 and a superior cycle stability with a negligible capacity decay of 0.016%percycle over 3,200 cycles at 0.4 A·g^1.Theoretical calculations reveal that the nitrogen-doping in graphene can stabilize the NG@SnSe/Cstructure and improve the electrical conductivity.The reversible Na-ion storage mechanism of SnSe is further investigated by in-situ X-raydiffraction/ex-s/tu transmission electron microscopy.Furthermore,assembled sodium-ion hybrid capacitor full-cells comprising our NG@SnSe/Canode and an active carbon cathode harvest a high energy/power density of 115.5 Wh·kg^-1/5,742 W·kg^-1,holding promise for next-generationen ergy storages. | Chen Lu Zhenzhu Li Zhou Xia Haina Ci Jingsheng Cai Yingze Song Lianghao Yu Wanjian Yin Shixue Dou Jingyu Sun Zhongfan Liu | 2019 | Nano Research2019,12,12: | 7 |
| 5 | Systematic Identification of the Light-quality Responding Anthocyanin Synthesis-related Transcripts in Petunia Petals显示文摘Previous studies have shown that high light intensity can induce anthocyanin synthesis(AS)in petunia plants.To identifywhich kind of light quality plays a role in inducing such metabolic process,and what transcripts participate in controlling it,we carried out whole-transcriptome sequencing and analysis of petunia petals treated with different light-quality conditions.Among the red and white light treatments,a total of 2205 differentially expressed genes and 15,22,and 20 differentially expressed circRNAs,miRNAs,and lncRNAs,were identified respectively.The AS-related genes,including the structural genes CHSj,F3H,F35H,DFR,and ANS,and the regulatory genes AN4,DPL,PHZ and MYBx were found to be downregulated under red light condition compared with their levels under white light condition.Furthermore,the light photoreceptor Cryptochrome 3(CRY3)and a series of light-dependent genes,such as PIF,HY5,andBBXs,were also determined to respond to the light treatments.The anthocyanin contents in early petunia petals under red light were significantly lower than that under white and blue light.The results of qRT-PCR further confirmed the expression pattern of some AS-related and light-response genes in response to different light quality.Yeast two-hybrid results showed that the key elements in the light signal pathway,HY5 can interact with BBX19,BBX24 and BBX25.And PHZ,the important AS regulator can induce anthocyanin synthesis in response to blue light quality fromtransient expression analysis in petunia petals.These findings presented here not only deepen our understanding of how light quality controls anthocyanin synthesis,but also allow us to explore potential target genes for improving pigment production in petunia flower petals. | Zhenzhu Fu Hongquan Shang Hui Jiang Jie Gao Xiaoyu Dong Huijuan Wang Yanmin Li Limin Wang Jing Zhang Qingyan Shu Yacong Chao Menglan Xu Rui Wang Liangsheng Wang Hechen Zhang | 2020 | Horticultural Plant Journal2020,6,6: | 7 |
| 6 | An animal model of cerebral palsy induced by prenatal exposure to lipopolysaccharide and hypoxia显示文摘BACKGROUND:Neonatal cerebral palsy is mainly caused by prenatal factors.At present, an animal model of prenatal infection and early postnatal hypoxia does not exist.OBJECTIVE:To observe morphology and motor performance following prenatal infection and hypoxic insult-induced brain damage of neonatal rats to verify the feasibility to establish a model of cerebral palsy.DESIGN, TIME AND SETTING:A randomized, controlled, animal experiment was performed at the Laboratories of Xinjiang Center for Disease Control and Prevention from September 2007 to June 2008.MATERIALS:The hypoxic incubator was purchased from Shanghai Pediatric Medical Institute, China.Lipopolysaccharide (LPS, Escherichia coli, O55:B5) was purchased from Sigma-Aldrich (St.Louis, MO, USA).METHODS:A total of 27 Wistar rats, aged 7 days, were randomly assigned to sham-surgery group (n=15) with no carotid artery incision or hypoxia treatment, hypoxia/ischemia (H/I) group (n=12) undergoing ligature of the right common carotid artery followed by exposure to hypoxia at postnatal day 7 (P7), and LPS/H group (n=19), in which pregnant rats were exposed in utero to LPS followed by prenatal hypoxia at embryonic day 16.MAIN OUTCOME MEASURES:Behavior, compound muscle action potential, and pathological changes were observed in 28-day-old rats.RESULTS:The footprint repeat space showed that left limb footprint repeatability in the H/I and LPS/H groups was lower than in the sham-surgery group (P<0.05).The space between the footprints was larger and unstable.Hind limb quadricep compound muscle action potential in the H/I and LPS/H groups showed lower wave amplitude compared with the sham-surgery group (P<0.05).Hematoxylin and eosin staining showed irregular cells around the ventricle, as well as periventricular leukomalacia.CONCLUSION:An animal model of cerebral palsy was established, which simulated the human condition most likely associated with occurrence of this disease.This model could be used for experimental studies related to cerebral palsy. | Gang Chen Yanrong HU Wei Liu Jiang Li Linbao Wen Jianxin Li Lihui Zhao Xiaopeng Yang Yi Zhu Zhenzhu Sun Guangming Chi | 2010 | Neural Regeneration Research2010,5,14: | 4 |
| 7 | TEM investigations of South Atlantic Ridge 13.2°S hydrothermal area显示文摘According to the exploration contract about polymetallic sulfides in the SWIR(Southwest Indian Ridge)signed by China with the International Seabed Authority,to delineate sulfide minerals and estimate resource quantity are urgent tasks.We independently developed our first coincident loop Transient Electromagnetic Method(TEM)device in 2010,and gained the TEM data for seafloor sulfide at South Atlantic Ridge 13.2°S in June 2011.In contrast with the widely applied CSEM(Marine controlled-source electromagnetic)method,whose goal is to explore hydrocarbons(oil/gas)of higher resistivity than seawater from 102to 103m below the sea floor,the TEM is for low resistivity minerals,and the target depth is from 0 to 100 m below the sea floor.Based on the development of complex sulfide geoelectrial models,this paper analyzed the TEM data obtained,proposing a new method for seafloor sulfide detection.We present the preliminary trial results,in the form of apparent resistivity sections for both half-space and full-space conditions.The results correspond well with the observations of the actual hydrothermal vent area,and the detection depth reached50–100m below the bed,which verified the capability of the equipment. | TAO Chunhui XIONG Wei XI Zhenzhu DENG Xianming XU Yixian | 2013 | Acta Oceanologica Sinica2013,32,12: | 3 |
| 8 | Analysis on the Management of Suppliers' Purchasing Partnership显示文摘 | Zhenzhu Zhang | 2005 | Chinese Business Review2005,4,6: | 2 |
| 9 | Nature-inspired Cu2O@CoO tree-like architecture for robust storage of sodium显示文摘We report a nature-inspired design of tree-like architecture of cuprous oxide(Cu2O)stem and cobalt oxides(CoO)branch serving as an efficient anode for sodium-ion batteries.The construction of stembranch architectures involves the growth of Cu2O nanorods and the subsequent deposition of CoO nanowires.Due to abundant active sites and full exposure to electrolyte,such a Cu2O@CoO stem-branch architecture demonstrates a robust storage toward Na^+ions,affording a capacity retention of^100%over 300 continuous cycles and a remarkable rate capability of 296 mAh g^-1 at 1 A g^-1.This result clearly shows the potential of nature-inspired materials engineering may find extensive applications in the design of high-performance electrodes for rechargeable batteries. | Zhenzhu Wang Menglei Sun Jiangfeng Ni Liang Li | 2020 | Journal of Materials Science & Technology2020,52,18: | 2 |
| 10 | Soil temperature and biotic factors drive the seasonal variation of soil respiration in a maize (Zea mays L.) agricultural ecosystem显示文摘 | Guangxuan Han Guangsheng Zhou Zhenzhu Xu Yang Yang Jingli Liu Kuiqiao Shi | 2007 | Plant and Soil (-)2007,,1: | 1 |
| 11 | Freestanding nanosheets of 1T-2H hybrid MoS_(2) as electrodes for efficient sodium storage显示文摘Molybdenum disulfide(MoS_(2)) is a promising electrode material for sodium-ion batteries as it offers a large capacity through a distinct conversion reaction.However,the electrochemical potential of MoS_(2) is often restrained by the poor conductivity as the dominant 2 H phase is a semiconductor while the metallic1 T phase is thermodynamically unstable.In this work,we report a hybrid design and material preparation of freestanding nanosheets of MoS_(2) composed of both 1 T and 2 H phases based on mild hydrothermal reaction.The introduction of the metallic 1 T-MoS_(2) phase into 2 H-MoS_(2) and their intimate hybridization enable a significant improvement in electronic conductivity,while the freestanding architecture avoids possible electrochemical aggregation.When used as electrodes for sodium storage,such a hybrid MoS_(2) affords a high capacity of~500 mA h g^(-1) at 0.5 A g^(-1) after 300 cycles,and retains capacity of~200 mA h g^(-1) at a high current rate of 4 A g^(-1),thus demonstrating their potential in high-performance battery applications. | Haiyang Yu Zhenzhu Wang Jiangfeng Ni Liang Li | 2021 | Journal of Materials Science & Technology2021,,8: | 1 |
| 12 | Influenza A virus‐encoded NS 1 virulence factor protein inhibits innate immune response by targeting IKK显示文摘 | Shijuan Gao Liping Song Jiandong Li Zhenzhu Zhang Haiyan Peng Wei Jiang Qingtao Wang Tiebang Kang Shuai Chen Wenlin Huang | 2012 | Cell Microbiol2012,,12: | 1 |
| 13 | Understanding mineral behaviors during anthracite fluidized-bedgasification based on slag characteristics显示文摘 | Li Fenghai Li Zhenzhu Huang Jiejie | 2014 | Applied Energy2014,131,: | 1 |
| 14 | Statistical characteristics of forest litterfall in China显示文摘Dear Editor,Litterfall represents a major pathway of carbon and mineral transfer from vegetation to soils,and thus is an important ecological process in carbon and nutrient cycling.Annual litterfall production also influences the amount of fuel accumulated in the forests,which serves as a part of an indicator | Bingrui Jia Zhenzhu Xu Guangsheng Zhou Xiaojie Yin | 2018 | Science China(Life Sciences)2018,61,3: | 1 |
| 15 | Alternating Terpolymers Based on Tunable Bi-donors with Manipulating Energy Levels and Molecular Geometry显示文摘Three novel regular acceptor-donorl-acceptor-donor2(A-D1-A-D2) terpolymers were prepared via em-bedding a second donor(D2) unit into the traditional D-A backbone to manipulate the energy levels and moleculargeometry with no complex synthesis or solubility loss. In these A-D1-A-D2 terpolymers, benzodithiophene(BDT, D1)and diketopyrrolopyrrole(DPP, A) were selected as the basic skeleton, and the dithienopyrrole(DTPy), carbazole(CZ)and fluorine(FL) units with different electron donating ability were chosen as the second donor trait(D2). The HOMOenergy levels can be effectively modulated by only varying D2 unit because of the push-pull interaction between do-nor and acceptor units. Versus the D-A bipolymer PDPP-BDT, incorporation of the D2 unit into the copolymers candistinctly lower the highest occupied molecular orbital(HOMO) levels to -5.47 eV for PDDPP-BDT-DTPy, -5.38 eVfor PDDPP-BDT-CZ and -5.23 eV for PDDPP-BDT-FL, which shows the strong dependence on electron-donatingability. Density functional theory(DFT) simulation and X-ray diffraction(XRD) measurements also reveal the effectof the D2 units on the molecular geometry of the terpolymers and their molecular packing. Notably, aPDDPP-BDT-DTPy combined with a thiophene ring and forked tail pendant away from the backbone had less back-bone torsion and more compact packing than the other two counterparts. These results demonstrate that embedding asecond donor(D2) unit into the backbone to construct an A-D1-A-D2 structure can be an effective and direct strategyto manipulate the energy levels and molecular geometry and develop organic semiconducting materials. | CHEN Zhenzhu YANG Jia WU Feiyan CHEN Lie CHEN Yiwang | 2017 | Chemical Research in Chinese Universities2017,33,2: | 1 |
| 16 | Electrospun Materials for Batteries Moving Beyond Lithium‑Ion Technologies显示文摘Innovation and optimization have shifted battery technologies beyond the use of lithium ions and fostered the demand for enhanced materials,which are vital factors determining the energy,power,durability,and safety of systems.Current battery materials vary in their sizes,shapes,and morphology,and these have yet to meet the performance standards necessary to prevent deterioration in regard to the efficiency and reliability of beyond-lithium technologies.As a versatile and feasible technique for producing ultrathin fibers,electrospinning has been extensively developed to fabricate and engineer nanofibers of functional materials for battery applications.In this review,the basic concepts and characteristics of beyond-lithium batteries are expounded,and the fundamentals of electrospinning are reviewed.The aim is to provide a guide to researchers going into this field.Focuses are placed on how electrospinning can address some of the key technical challenges facing beyond-lithium technologies.We hope the knowledge presented in this work will stimulate the design of electrospun materials for future battery applications. | Jie Wang Zhenzhu Wang Jiangfeng Ni Liang Li | 2022 | Electrochemical Energy Reviews2022,5,2: | 1 |
| 17 | Recent progress in Pb-free stable inorganic double halide perovskites显示文摘Although the power conversion efficiency(PCE) of CH_3 NH_3 PbI_3-based solar cells has achieved 22.1%,which is comparable to commercialized thin-film CdTe and Cu(In,Ga)Se_2 solar cells, the long-term stability is the main obstacle for the commercialization of perovskite solar cells. Recent efforts have been made to explore alternative inorganic perovskites, which were assumed to have better stability than organic-inorganic hybrid CH_3 NH_3 PbI_3. In this short review, we will keep up with experiments and summarize recent progresses of inorganic double halide perovskite, in particular to Cs_2 AgBiBr_6, Cs_2 AgInCl_6, Cs_2 InBiBr_6 and their family members. We will also share our opinions on the promise of such class of materials. | Zhenzhu Li Wanjian Yin | 2018 | Journal of Semiconductors2018,39,7: | 1 |
| 18 | Turbidite Reservoirs in the Dongying Sag,Bohai Bay Basin:Interactions between Carbonate Cementation and Hydrocarbon Charge显示文摘Turbidite sandstones have become increasingly significant in hydrocarbon exploration.Carbonate cementation occur commonly in turbidite reservoirs developing within the Paleocene lacustrine basins,Northeastern China.This study utilizes core data,thin section data and production data to investigate the interaction between the carbonate cementation and hydrocarbon charge within turbidite reservoirs in the Niuzhuang Sub-sag of the Dongying Sag,Bohai Bay Basin,East China.The results reveal that the carbonate cementation is mainly developed at the top and bottom of the turbidite sandbodies,and even forms carbonate cement shells.Three stages of hydrocarbon accumulation are identified based on fluid inclusion analysis:stage I(27.5–24.6 Ma),stage II(14.0–5.0 Ma),and stage III(5.0–0 Ma).The interaction between the carbonate cementation and hydrocarbon charge has significant controls on the formation of a turbidite reservoir.The temporal relations and intensity relations between the two factors should be considered significantly.Moreover,hydrocarbon charge during the early stage can inhibit the carbonate cementation,favoring the hydrocarbon accumulation in turbidite reservoirs.Many deep-lacustrine turbidite sandbodies surrounded by source rocks with abnormal high pressure,are also favorable for hydrocarbon accumulation.These results suggest that some deeply buried turbidite sandbodies with similar geological settings have high potential for hydrocarbon exploration. | CHEN Xiaolan ZHOU Zhenzhu JIA Haibo WANG Jian XIA Haiyang CHEN Yong | 2021 | Acta Geologica Sinica(English Edition)2021,95,2: | 1 |
| 19 | VEGF-A not Ang2 mediates endothelial-like differentiation of immatureDCs by ERK1/2 signaling in the microenvironment of human colon adenocarcinoma显示文摘 | Jing Lu Kangdong Liu Jimin Zhao Jun Zhao Junfen Ma Hongyan Yang Youtian Huang Zhenzhu Qin Ruihua Bai Lili Jiang Fengshou Lv Pei Li Wenhai Yan Mingyao Zhao Ziming Dong | 2011 | International Journal of Oncology2011,,6: | 1 |
| 20 | Combined effects of water stress and high temperature on photosynthesis, nitrogen metabolism and lipid peroxidation of a perennial grass Leymus chinensls 显示文摘 | XU Zhenzhu ZHOU Guangsheng | 2006 | Planta2006,224,5: | 1 |