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| 1 | Effects of urea plus nitrate pretreated rice straw and corn oil supplementation on fiber digestibility,nitrogen balance,rumen fermentation,microbiota and methane emissions in goats显示文摘Background: Urea pretreatment is an efficient strategy to improve fiber digestibility of low quality roughages for ruminants. Nitrate and oil are usually used to inhibit enteric methane(CH4) emissions from ruminants. The objective of this study was to examine the combined effects of urea plus nitrate pretreated rice straw and corn oil supplementation to the diet on nutrient digestibility, nitrogen(N) balance, CH4 emissions, ruminal fermentation characteristics and microbiota in goats. Nine female goats were used in a triple 3 × 3 Latin Square design(27 d periods). The treatments were: control(untreated rice straw, no added corn oil), rice straw pretreated with urea and nitrate(34 and 4.7 g/kg of rice straw on a dry matter [DM] basis, respectively, UN), and UN diet supplemented with corn oil(15 g/kg soybean and15 g/kg corn were replaced by 30 g/kg corn oil, DM basis, UNCO).Results: Compared with control, UN increased neutral detergent fiber(NDF) digestibility(P < 0.001) and copies of protozoa(P < 0.001) and R. albus(P < 0.05) in the rumen, but decreased N retention(-21.2%, P < 0.001), dissolved hydrogen concentration(-22.8%, P < 0.001), molar proportion of butyrate(-18.2%, P < 0.05),(acetate + butyrate) to propionate ratio(P < 0.05) and enteric CH4 emissions(-10.2%, P < 0.05). In comparison with UN, UNCO increased N retention(+34.9%, P < 0.001) and decreased copies of protozoa(P < 0.001) and methanogens(P < 0.001). Compared with control, UNCO increased NDF digestibility(+8.3%, P < 0.001), reduced ruminal dissolved CH4 concentration(-24.4%, P < 0.001) and enteric CH4 emissions(-12.6%, P < 0.05).Conclusions: A combination of rice straw pretreated with urea plus nitrate and corn oil supplementation of the diet improved fiber digestibility and lowered enteric CH4 emissions without negative effects on N retention. These strategies improved the utilization of rice straw by goats. | Xiumin Zhang Rodolfo F.Medrano Min Wang Karen A.Beauchemin Zhiyuan Ma Rong Wang Jiangnan Wen Lukuyu A.Bernard Zhiliang Tan | 2019 | Journal of Animal Science and Biotechnology2019，10，2： | 10 |
| 2 | Rumen-protected glucose supplementation in transition dairy cows shifts fermentation patterns and enhances mucosal immunity显示文摘Manipulation of perinatal diets,such as supplementing feed with rumen-protected glucose(RPG),has been positively regarded as a strategy to improve milking performance.This study was conducted to assess the effects of RPG on the fermentation profiles,resident microbiota and mucosal immunity in the cecum.Ten Holstein dairy cows were randomly assigned to either a 25 g/kg RPG diet(DM basis)or a 11 g/kg coating fat diet(control,CON).Compared with the CON group,the acetate-to-propionate ratio was lower in the RPG group.Gene expression analysis indicated that RPG supplementation tended to upregulate the expression of Na^(+)/H^(+)hydrogen exchanger 3(NHE3)(P=0.076).RPG supplementation downregulated the expression of genes involved in self-rehabilitation such as matrix metalloproteinase 1(MMP1),MMP3,MMP9 and MMP13.Additionally,the mRNA expression of genes involved in immunity including Toll-like receptors(TLR4,TLR6 and TLR7)and proinflammatory cytokines(immune interferon gamma[IFNG]and interleukins interleukin 17 A[IL7 F],IL17 A,IL22),was downregulated by RPG supplementation.Nonetheless,no differences existed in the bacterial copy number and beta diversity between the 2 groups.Overall,supplementation with RPG would probably cause a shift towards propionate production in the cecal digesta,and promote the immune homeostasis of the cecal mucosa in transition dairy cows.Our results extended the basic understanding of RPG supplementation and utilization in transition dairy cows in terms of host microbe interplay in the cecum. | Xiaoli Zhang Xiaopeng Li Jian Wu Jinzhen Jiao Zhixiong He Zhiliang Tan Xuefeng Han | 2021 | Animal Nutrition2021，，4： | 4 |
| 3 | Effects of restrictions on maternal feed intake on the immune indexes of umbilical cord blood and liver Toll-like receptor signaling pathways in fetal goats during pregnancy显示文摘Background: Liver has important immune function during fetal development and after birth.However,the effect of maternal malnutrition on immune function of the fetal liver is rarely reported.In this study,twelve pregnant goats(Xiangdong black goat,at d 45 of gestation) were assigned to the control group(fed 100% of nutritional requirements) and the restriction group(fed 60% of the intake of the control group) during gestation from d 55 to100.Fetal goats were harvested at d 100 of gestation and immune indexes and amino acid profiles of the umbilical cord blood and liver Toll-like receptors(TLRs) signaling pathways were measured.Results: Maternal body weight in the restriction group was lower than the control group(P < 0.05).Maternal feed intake restriction decreased(P < 0.05) heart weight,heart index,alkaline phosphatase and serum amyloid protein A in the umbilical cord blood(UCB).Moreover,only histidine was decreased in the restricted group(P = 0.084),and there were no differences in other amino acids contents in the UCB between the two groups(P > 0.05).The TLR2 and TLR4 mRNA expression in the fetal liver in the restriction group was greater(P < 0.05) than that in the control group.Furthermore,the mRNA expression levels of myeloid differentiation primary response 88(MyD88),TNF receptor associated factor 6,nuclear factor kappa B subunit 1,NFKB inhibitor alpha,IFN-β,TGF-β,TNF-α and IL-1β in the restricted group were upregulated(P < 0.05),and the expression of TLR3(P = 0.099) tended to be higher in the restricted group.However,protein levels of TLR2,TLR4,IκBα,phosphorylated IκBα,phosphorylated IκBα/total IκBα,TRIF and MyD88 were not affected(P > 0.05) by maternal intake restriction.Conclusions: These results revealed that the restriction of maternal feed intake influenced the development of heart and hepatic protein synthesis at the acute phase of fetal goats and upregulated the mRNA expression of genes involved in MyD88-dependent signaling pathways and of target cytokines. | Wenxun Chen Qiongxian Yan Hong Yang Xiaoling Zhou Zhiliang Tan | 2019 | Journal of Animal Science and Biotechnology2019，10，3： | 3 |
| 4 | Maternal intake restriction programs the energy metabolism, clock circadian regulator and m TOR signals in the skeletal muscles of goat offspring probably via the protein kinase A-cAMP-responsive element-binding proteins pathway显示文摘The biological mechanism by which maternal undernutrition increases the metabolic disorder risk of skeletal muscles in offspring is not fully understood.We hypothesize that maternal intake restriction influences metabolic signals in the skeletal muscles of offspring via a glucagon-mediated pathway.Twentyfour pregnant goats were assigned to the control group(100%of the nutrients requirement,n=12)and restricted group(60%of the control feed allowance from pregnant days 45 to 100,n=12).Blood and Longissimus thoracis muscle were sampled from dams(100 d of gestation),fetuses(100 d of gestation),and kids(90 d after birth)in each group.The data were analyzed using the linear MIXED model,with the multiple comparison method of SIDAK applied.Intake restriction reduced(P<0.05)the total blood protein of dams and fetuses.Maternal restriction decreased(P<0.05)the cAMP-responsive element-binding protein 1(CREB1),CREB-binding protein(CREBBP),protein kinase A(PKA),aryl hydrocarbon receptor nuclear translocator-like protein 1(BMAL1),protein kinase B(AKT1),mammalian target of rapamycin(mTOR),and regulatory-associated protein of mTOR(RPTOR)mRNA expression in the fetuses,and reduced(P<0.05)the CREBBP,nuclear receptor subfamily 1 group H member 3(NR1 H3),D-box binding PAR bZIP transcription factor(DBP)and PKA mRNA levels in the kids,but increased(P<0.05)the peroxisome proliferator-activated receptor gamma coactivator 1 alpha(PGC1 A)and tuberous sclerosis 2(TSC2)mRNA levels in the fetuses.The mRNA expression of clock circadian regulator(CLOCK)and TSC2 genes was increased(P<0.05)in the restricted kids.The protein expression of total PKA and phosphorylated PKA in the restricted fetuses and kids were downregulated(P<0.05),and the protein expression of total mTOR and phosphorylated mTOR were reduced(P<0.05)in the restricted fetuses and kids.Maternal intake restriction regulated fat oxidation,protein synthesis,and circadian clock expression in the muscles of the offspring probably via the glucagon-mediated PKA-CREB pathway,which reveals a noteworthy molecular pathway that maternal undernutrition leads to metabolic adaptation of skeletal muscle in offspring. | Xiaoling Zhou Qiongxian Yan Hong Yang Ao Ren Zhixiong He Zhiliang Tan | 2021 | Animal Nutrition2021，，4： | 2 |
| 5 | A mathematical model to describe the diurnal pattern of enteric methane emissions from non-lactating dairy cows post-feeding显示文摘Enteric methane emission is not only a source of energy loss in ruminants, but also a potent contributor to greenhouse gas production. To identify the nature and timing of interventions to reduce methane emissions requires knowledge of temporal kinetics of methane emissions during animal husbandry.Accordingly, a mathematical model was developed to investigate the pattern of enteric methane emissions after feeding in dairy cows. The model facilitated estimation of total enteric methane emissions(V,g) produced by the residual substrate(V1, g) and newly ingested feed(V2, g). The model was fitted to the10 h methane emission patterns after morning feeding of 16 non-lactating dairy cows with various body weights(BW), and the obtained parameters were used to predict the kinetics of 24 h methane emission for each animal. The rate of methane emission(g/h) reached a maximum within 1 to 2 h after feeding,followed by a gradual post-prandial decline to a basal value before the next feeding. The model satisfactorily fitted curves for each cow according to the criterion of goodness-of-fit, and provided biological descriptions for fluctuations in methane emissions based on basal V1 and feeding V2 in response to the changes in BW and dry matter intake(DMI) of different dairy cows. The basal V1 and feeding V2 are probably maintained by slow-and readily-degradable substrates, respectively. The former contributed at least 0.6 of methane production. In summary, the model provides a means to separate basal V1 and feeding V2 within V, and can be used to predict 24 h emission from a single feeding period. | Min Wang Rong Wang Xuezhao Sun Liang Chen Shaoxun Tang Chuangshe Zhou Xuefeng Han Jinghe Kang Zhiliang Tan Zhixiong He | 2015 | Animal Nutrition2015，，4： | 2 |
| 6 | China’s low-emission pathways toward climate-neutral livestock production for animal-derived foods显示文摘Animal-derived food production accounts for 19%of global anthropogenic greenhouse gas(GHG)emissions.Diet followed in China is ranked as lowcarbon emitting(i.e.,0.21 t CO_(2-)eq per capita in 2018,ranking at 145^(th) of 168 countries)due to the low average animal-derived food consumption rate,and preferential consumption of animal-derived foods with lower GHG emissions(i.e.,pork and eggs versus beef and milk). | Rong Wang Zhaohai Bai Jinfeng Chang Qiushuang Li Alexander N.Hristov Pete Smith Yulong Yin Zhiliang Tan Min Wang | 2022 | The Innovation2022，3，2： | 2 |
| 7 | Deadbands and the Dynamic Response and Performance of Large Water Transfer Canal System显示文摘An operating simulation mode for multireach canal system in series under gate regulating is established. The discharge feedforward plus water lever feedback PID controller was adopted. And the performance indicators are introduced to evaluate the control effects of canal operation. Influence on dynamic response process and dynamic performance as well as the control actions of canal system are studied according to the variation of the gate deadband and water level deadband. The results showed that the larger the gate deadband, the worse, the control effect of canal system over water level, and so done the stable process of gate discharge, yet the stable process of gate opening was getting better, while the upstream gate regulation of each canal pool was less at the time when canal stabilizes; the closer to downstream end of canal, the lager steady-state error of this canal pool was, and the lager influence of gate deadband on the steady-state error as well as response time of this canal pool was; the canal system can not acquire superiority in both the control performance and control actions when only the water level deadband was established. | DING Zhiliang WANG Changde TAN Guangming GUAN Guanghua | 2009 | Journal of Northeast Agricultural University(English Edition)2009，16，2： | 2 |
| 8 | Overexpression of OsSPL9 enhances accumulation of Cu in rice grain and improves its digestibility and metabolism显示文摘Copper(Cu)is an essential trace mineral element for all forms of life,and is an important structural component and co-factor for a variety of metalloenzymes(Pen^a et al.,1999;Bertinato and L'Abbe,2004).In humans,Cu deficiency is not common because of the ubiquitous occurrence of Cu and ease of gastrointestinal absorption(Zidar et al.,1977;Uauy et al.,1998).However,because of the low Cu content in most sources of feed,the use of Cu as a growth promoter to maximize animal production has been well documented in animal feeding(Braude,1945;Lu et al.,2010).Pre- | Mingfeng Tang Chuanshe Zhou Lu Meng Donghai Mao Can Peng Yuxing Zhu Daoyou Huang Zhiliang Tan Caiyan Chen Chengbing Liu Dechun Zhang | 2016 | Journal of Genetics and Genomics2016，43，11： | 2 |
| 9 | An unusual COVID-19 case with over four months of viral shedding in the presence of low neutralizing antibodies: a case report显示文摘The ongoing coronavirus disease 2019(COVID-19)pandemic is a global public health crisis,causing social and economic disasters in many countries.In China,two-consecutive negative results of nucleic acid tests for SARS-CoV-2 from the respiratory samples are required to end the quarantine of COVID-19 patients.However,clinicians face a dilemma in case of patients with long-term viral shedding.This report described an unusual COVID-19 case who had persistent viral RNA positivity for more than 4 months after initial illness in the presence of low neutralizing antibodies,but without prolonged clinical symptoms.Multiple anti-viral drug treatments had no impact and there was no evidence of re-infection.When the patient was self-quarantined at home,no infection occurred to the three family members living with her for 15 to 19 days.Sputum viral culture in BSL-3 laboratory on the 102nd day after symptom onset was negative.From the 129th day on,8 continuous nucleic acid tests of sputum samples showed negative results.The patient was discharged on 137th days since symptom onset.In conclusion,viral RNA shedding in the sputum of the COVID-19 patient may last over 4 months.As no evidence shows the existence of infectious virus,two-consecutive negative nucleic acid tests may not be the prerequisite for ending quarantine of COVID-19 patients with prolonged viral shedding. | Wei Chen Zhiliang Hu Changhua Yi Yun Chi Qingfang Xiong Chee Wah Tan Yongxiang Yi Lin-Fa Wang | 2020 | The Journal of Biomedical Research2020，34，6： | 1 |
| 10 | Inverted polymer solar cells with TiO_2 electron extraction layers prepared by magnetron sputtering显示文摘TiO2 thin films deposited by magnetron sputtering possess excellent optical transmittance,high refractive index,good adhesion and chemical stability.In this manuscript,TiO2 thin films deposited by magnetron sputtering was used for the first time as an electron extraction layer in inverted polymer solar cells(IPSCs),and the effect of the TiO2 thickness on the photovoltaic performance of P3HT:PC61BM IPSCs was investigated.The highest PCE value of 3.75%was obtained when the thickness of TiO2thin films was in the range between 42 nm and 73 nm.The absorption properties,morphology and structure of the TiO2 films were characterized by UV-Vis spectroscopy,SEM and Raman spectroscopy,and were related to the device performance of P3HT:PC61BM IPSCs.The results indicate that TiO2 films deposited by magnetron sputtering are an excellent electron extraction layer for IPSCs. | JIANG ZhiLiang YANG Dong WANG Nan ZHANG FuJun ZHAO Bin TAN SongTing ZHANG Jian | 2013 | Science China Chemistry2013，56，11： | 1 |
| 11 | The Influence of Cu (II) on the Formation and Distribution of Disinfection By- Products during the Chlorination of Drinking Water显示文摘 | Shaogang Liu Zhiliang Zhu Xuecai Tan | 2013 | Water Air Soil Pollute2013，224，： | 1 |
| 12 | Disruption of Klf4 in Villin-Positive Gastric Progenitor Cells Promotes Formation and Progression of Tumors of the Antrum in Mice显示文摘 | Qiang Li Zhiliang Jia Li Wang Xiangyu Kong Qi Li Kun Guo Dongfeng Tan Xiangdong Le Daoyan Wei Suyun Huang Lopa Mishra Keping Xie | 2012 | Gastroenterology2012，，3： | 1 |
| 13 | Delay characteristics of silicon controlled rectifier-based electrostatic discharge protection devices显示文摘 | CHEN Yongguang LIU Jin TAN Zhiliang | 2010 | High Voltage Engineering2010，37，9： | 1 |
| 14 | Effects of alkyl polyglycoside,a nonionic surfactant and forage-to-concentrate ratio on rumen fermentation,amino acid composition of rumen content,bacteria and plasma in goats显示文摘 | Zeng Bo Tan Zhiliang Tang Shaoxun | 2011 | Archives of Animal Nutrition2011，65，3： | 1 |
| 15 | Alterations of endotoxin distribution across different biofluids and relevant inflammatory responses by supplementing L-theanine in dairy cows during heat stress显示文摘The present trial was performed to reveal the regulatory effects of L-theanine on the levels of lipopolysaccharide(LPS)endotoxin within different biofluids,as well as relevant inflammatory responses of dairy cattle under heat stress conditions.Thirty lactating Chinese Holstein dairy cattle(189±47 d in milk,and 2±1 parities)were allocated in a completely randomized design to each of 3 dietary treatments:the control(CON,0 g/d per cow L-theanine),the low L-theanine dosage treatment(LL,16 g/d per cow L-theanine),and the high L-theanine dosage treatment(HL,32 g/d per cow L-theanine).This trial consisted of 38 d(7 d for adaption and 31 d for data and sample collection),and sample collection for rumen liquid,blood plasma or serum,and milk were conducted on the d 27 and 38,respectively.Dairy cattle were constantly exposed to environmental heat stress during this experiment according to the recorded temperature-humidity index(THI).In the LL treatment,LPS concentration in rumen liquid was higher(P<0.05),whilst LPS densities in plasma and milk were lower(P<0.05)than those of the CON.Supplementing L-theanine at 2 dosages both significantly lowered(P<0.05)the level of interleukin(IL)-1βin the serum.Results of the present study suggested that L-theanine could be a promising additive in reducing the detrimental effects of heat stress on dairy cows,and L-theanine supplementation at 16 g/d per cow is preferred because it reduced the LPS translocation into the peripheral blood and LPS accumulation in the milk,as well as mitigated LPS-induced inflammatory reactions in dairy cows during heat stress.Further studies are necessitated to investigate the underlying mechanisms of L-theanine in LPS alteration and inflammation alleviation. | Zuo Wang Lingmei Zhang Zhicai Li Yuannian Yu Lingyuan Yang Peihua Zhang Weijun Shen Fachun Wan Jianhua He Wenjun Xiao Dasheng Yang Zhiliang Tan Shaoxun Tang | 2021 | Animal Nutrition2021，，4： | 1 |
| 16 | Lipid metabolism and m^(6)A RNA methylation are altered in lambs supplemented rumen-protected methionine and lysine in a low-protein diet显示文摘Background:Methionine or lysine has been reported to influence DNA methylation and fat metabolism,but their combined effects in N6-methyl-adenosine(m^(6)A)RNA methylation remain unclarified.The combined effects of rumen-protected methionine and lysine(RML)in a low-protein(LP)diet on lipid metabolism,m^(6)A RNA methylation,and fatty acid(FA)profiles in the liver and muscle of lambs were investigated.Sixty-three male lambs were divided into three treatment groups,three pens per group and seven lambs per pen.The lambs were fed a 14.5%crude protein(CP)diet(adequate protein[NP]),12.5%CP diet(LP),and a LP diet plus RML(LP+RML)for 60 d.Results:The results showed that the addition of RML in a LP diet tended to lower the concentrations of plasma leptin(P=0.07),triglyceride(P=0.05),and non-esterified FA(P=0.08).Feeding a LP diet increased the enzyme activity or m RNA expression of lipogenic enzymes and decreased lipolytic enzymes compared with the NP diet.This effect was reversed by supplementation of RML with a LP diet.The inclusion of RML in a LP diet affected the polyunsaturated fatty acids(PUFA),n-3 PUFA,and n-6 PUFA in the liver but not in the muscle,which might be linked with altered expression of FA desaturase-1(FADS1)and acetyl-Co A carboxylase(ACC).A LP diet supplemented with RML increased(P<0.05)total m^(6)A levels in the liver and muscle and were accompanied by decreased expression of fat mass and obesity-associated protein(FTO)and alk B homologue 5(ALKBH5).The m RNA expressions of methyltransferase-like 3(METTL3)and methyltransferase-like 14(METTL14)in the LP+RML diet group were lower than those in the other two groups.Supplementation of RML with a LP diet affected only liver YTH domain family(YTHDF2)proteins(P<0.05)and muscle YTHDF3(P=0.09),which can be explained by limited m^(6)Abinding proteins that were mediated in m RNA fate.Conclusions:Our findings showed that the inclusion of RML in a LP diet could alter fat deposition through modulations of lipogenesis and lipolysis in the liver and muscle.These changes in fat metabolism may be associated with the modification of m^(6)A RNA methylation. | Kefyalew Gebeyew Chao Yang Hui Mi Yan Cheng Tianxi Zhang Fan Hu Qiongxian Yan Zhixiong He Shaoxun Tang Zhiliang Tan | 2023 | Journal of Animal Science and Biotechnology2023，14，1： | 0 |
| 17 | A water-soluble β-glucan improves growth performance by altering gut microbiome and health in weaned pigs显示文摘Beta-glucan has been shown to have a beneficial effect on gastrointestinal health.This experiment was conducted to investigate the effects ofβ-glucan isolated from Agrobacterium sp.ZX09 on growth performance and intestinal health of weaning pigs.A total of 108 weaned pigs(21 d of age;6.05±0.36 kg)were randomly divided into 3 groups(6 pens/group;6 pigs/pen),and the groups were each treated with the following diets:1)basal diet,2)basal diet supplemented with 20 mg/kg olaquindox,3)basal diet supplemented with 200 mg/kgβ-glucan,for 21 d.Compared with the control group,pigs fed with200 mg/kgβ-glucan had greaterBW,average daily gain and duodenal villus height to crypt depth ratio(P<0.05).Olaquindox increased the duodenal or jejunal villus height of pigs compared withβ-glucan.Compared with the control group,β-glucan tended to increase the occludin mRNA expression in the jejunum(0.05 | Yuliang Wu Xue Li Hongnan Liu Yanjun Du Jian Zhou Lijun Zou Xia Xiong Huilin Huang Zhiliang Tan Yulong Yin | 2021 | Animal Nutrition2021，，4： | 0 |
| 18 | Alterations in nutrient digestibility and performance of heat-stressed dairy cows by dietary L-theanine supplementation显示文摘The purpose of this study was to investigate the effects of dietary L-theanine supplementation on apparent nutrient digestibility,milk yield,milk composition,and blood biochemical indices of dairy cows under heat stress.Thirty Chinese Holstein cows(19.84±2.42 kg milk/d,192.36±40.77 d in milk and2±0.93 parities)were divided into 3 groups of 10 animals each.The control group was fed a basal total mixed ration(TMR)diet,while treatment 1(LTA16)and treatment 2(LTA32)groups were fed a basal TMR diet supplemented with L-theanine at 16 and 32 g/cow per day,respectively.The results showed that feeding the dairy cows with LTA16 treatment decreased(P<0.05)their rectal temperature,whereas feeding with LTA32 treatment decreased(P<0.05)their rumen fluid ammonia nitrogen content.In comparison to the control group,the supplementation of L-theanine had no significant effect(P>0.05)on the dry matter intake,nutrient digestibility,total volatile fatty acid(TVFA)concentration and molar proportion of volatile fatty acid,milk yield,milk composition,feed efficiency and antioxidant capacity of the dairy cows.The triglyceride(TG)content of the LTA32 group was significantly greater(P=0.014)than that of the control group.With the increase in L-theanine dosage,the serum cholesterol(CHOL)content significantly increased(P=0.013).The serum albumin(ALB;P=0.067),low-density lipoprotein cholesterol(LDL-C;P=0.053),and high-density lipoprotein cholesterol(HDL-C;P=0.067)contents showed an upward trend as L-theanine dosage increased.Ultimately,the results of this study show that supplementing dairy cow diet with L-theanine could decrease dairy cow rectal temperature,affect lipid metabolism,and potentially relieve the heat stress of dairy cows to some extent. | Lingyuan Yang Lingmei Zhang Peihua Zhang Yuli Zhou Xingguo Huang Qiongxian Yan Zhiliang Tan Shaoxun Tang Fachun Wan | 2022 | Animal Nutrition2022，，4： | 0 |
| 19 | Replacing ZnSO_(4)with Zn-glycine in the diet of goat promotes the pancreatic function of the offspring显示文摘Zinc supplementation in the diet of goats affects pancreas development in offspring.However,the impact of maternal inorganic and organic zinc supplementation in offspring is poorly defined.In this study,14 late-pregnant goats were assigned at random to the zinc sulfate group(ZnSO_(4),n=7)and the zinc-glycine chelate group(Zn-Gly,n=7),respectively.Serum samples and pancreas tissue were collected from kids whose mothers were fed ZnSO_(4)and Zn-Gly at the late pregnancy,respectively.Histologic examination showed no morphologic differences between the 2 groups.Pancreatic zinc content in kids tended to be increased when replacing ZnSO_(4)with Zn-Gly.The serum insulin concentration was greater and glucagon less in the Zn-Gly group when compared to the ZnSO_(4)group.The activities of lipase and chymotrypsin were enhanced when replacing ZnSO_(4)with Zn-Gly.Proteomics results showed that 234 proteins were differentially expressed between the 2 groups,some of which were associated with the secretion of insulin,enzyme activity and signal transduction.The results suggested that supply of dietary Zn-Gly to goats during late pregnancy promoted pancreatic function in offspring compared with dietary ZnSO_(4)supplementation.This provides new information about pancreatic function when supplementing different zinc sources in the diets of late pregnant goats. | Jinhe Kang Qiongxian Yan Chuanshe Zhou Xiaoling Zhou Zhiliang Tan | 2023 | Animal Nutrition2023，，1： | 0 |
| 20 | Yuanzheng 3 Upper Stage显示文摘Upper stage is an indispensable vehicle in the space transportation system.For its role in multi-satellite transportation area in China,the development of the Yuanzheng 3 upper stage was approved.The article introduces in detail the Yuanzheng 3 upper stage development requirements,task definition and systems as well as main features and performance including payload capacity and insertion accuracy for typical orbits,interfaces with satellites.The article also presents the development cycle of Yuanzheng 3 upper stage,which is divided into 3 stages including concept demonstration stage,prototype stage and flight proof stage.The Yuanzheng 3 upper stage,which will make its maiden flight in 2018,is capable of restarting more than 20 times,and operating for more than 48 hours.It is equivalent to mainstream upper stages in the world in terms of performance,such as restart times,in-orbit operation time,independent digital control system,and adaptable behavior for various tasks.Technologies tackled and accumulated in the development of the Yuanzheng 3 upper stage will lay a solid foundation for the development of future space transportation vehicles. | WU Zhiliang TAN Xuejun YAO Jian LIU Hanbing | 2017 | Aerospace China2017，18，1： | 0 |
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