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| 1 | Materials Experiment on Tiangong-2 Space Laboratory显示文摘During the China's Tiangong-2(TG-2) flight mission, the experiments of 18 kinds of material samples were conducted in space by using a Multiple Materials Processing Furnace(MMPF) mounted in the orbital module of the TG-2 space laboratory. After the experiments of 12 kinds of samples of the first and second batches were completed successfully, astronauts packed and brought them back to the ground by ShenzhouII spacecraft. By studying processing and formation on semiconductor and optoelectronics materials, metal alloys and metastable materials, functional single-crystal, micro-and nano-composite materials encapsulated in sample ampoules both in space and on Earth, we expect to explore some physical and chemical processes and mechanism of the materials formation that are normally obscured and therefore are difficult to study quantitatively on the ground due to the gravity-induced convection, to obtain the processing and synthesis technology for preparing high quality materials, and lead to the improvement and development of materials processing techniques on Earth, and also develop the experiment device and comprehensive ability for materials experiment in microgravity environment. This report briefly introduces the main points of each research work and preliminary comparative analysis results of 12 samples carried out by scientists undertaking research task. | LI Xiangyang LU Ye MENG Xiangjian WANG Jianlu WANG Reng CHEN Lidong HUA Zile LI Xiaoya SHI Jianlin LIU Jinfeng XU Guisheng WEI Bingbo XIE Wenjun YIN Zhigang ZHANG Xingwang JIANG Hongxiang LI Hong LUO Xinghong ZHANG Haifeng ZHAO Jiuzhou WANG Binbin PAN Mingxiang | 2018 | 空间科学学报2018，38，5： | 4 |
| 2 | Cold Stress-induced Glucosyltransferase CsUGT78A15 is Involved in the Formation of Eugenol Glucoside in Camellia sinensis显示文摘Eugenol is a natural phenolic compound known for its health-promoting properties and its ability to add a floral scent to tea plants.Plant eugenol glycosides have been identified and shown to make important contributions to fruit floral quality.However,the details of their biosynthesis and metabolism in tea plants are still unknown.Here,eugenol glucoside was unambiguously identified as a native metabolite in the tea plant,and its biosynthesis was shown to be induced by low temperature treatment.Through the analysis of UGTs induced by low temperature,the glycosyltransferase CsUGT78A15 was identified in tea,and its encoded protein was shown to catalyze the glucosylation of eugenol.Vmax/Km ratios showed that eugenol was the most suitable substrate for CsUGT78A15.Sugar donor preference analysis showed that CsUGT78A15 had a higher selectivity for glucose,followed by galactose and glucuronic acid.The expression of CsUGT78A15was correlatedwith the accumulation of eugenol glucoside in different tissues and genotypes of tea.Down-regulation of CsUGT78A15 led to a decreased eugenol glucoside content under cold stress,indicating that CsUGT78A15 plays an important role in the biosynthesis of eugenol glucoside under cold stress.The identification of eugenol glucoside in the tea plant and the discovery of a cold stress-induced eugenol glucosyltransferase in tea provide the foundation for the improvement of tea flavor under cold stress and the biotechnological production of eugenol glucoside. | Mingyue Zhao Binbin Cai Jieyang Jin Na Zhang Tingting Jing Jingming Wang Yuting Pan Zixiang Zhou Yifan Zhao Yingying Feng Feng Yu Mengting Zhang Yating Li Zhonghua Liu Chuankui Song | 2020 | Horticultural Plant Journal2020，6，6： | 4 |
| 3 | One-step synthesis of dimethyl ether from syngas on ordered mesoporous copper incorporated alumina显示文摘Ordered mesoporous copper incorporated Al_2O_3(Cu/Al_2O_3) with high Cu dispersion were prepared by a facile solution combustion synthesis method using aluminum nitrate and copper nitrate as oxidants and urea as fuel. It is a facile and green route to synthesize catalysts for dimethyl ether directly from syngas. Cu/Al_2O_3 catalysts were characterized by XRD, N_2 adsorption–desorption, SEM-EDS, and H_2-TPR.The results indicate that the catalysts obtain an ordered mesoporous structure and copper is homogenously dispersed. The mesoporous Cu/Al_2O_3 catalysts were utilized as bifunctional catalysts in syngas to dimethyl ether reaction(STD). The copper content affects the catalytic performance in STD reaction. The CO conversion and DME selectivity of Cu/Al_2O_3 with 15% copper molar ratio achieve 52.9% and 66.1%,respectively. Moreover, the mesoporous Cu/Al_2O_3 catalysts show excellent stability in STD reaction. | Yan Wang Yuexian Chen Feng Yu Dahai Pan Binbin Fan Jinghong Ma Ruifeng Li | 2016 | Journal of Energy Chemistry2016，25，5： | 3 |
| 4 | Two single nucleotide polymorphisms in the GDF5 gene are associated with development dysplasia of the hip in Chinese female population显示文摘Development dysplasia of the hip(DDH)is one of the most common hip defects in newborns.The main phenotypes of the disease are partial or whole femoral head extrusion from the acetabulum[1].Because the frequency of DDH in monozygotic twins was higher than that in dizygotic twins,and the affected individuals were often in the same family[2],we are focusing on the genetic factor in the present study. | ZHAO LiXi PAN Hong WANG Jing CHENG Zhi CHENG LongFei WANG BinBin MA Xu | 2013 | Science China(Life Sciences)2013，56，11： | 3 |
| 5 | The solar wind plasma upstream of Mars observed by Tianwen-1:Comparison with Mars Express and MAVEN显示文摘On the great journey to Mars,China’s first planetary exploration mission,the Tianwen-1 came within 26 million kilometers of Mars from 31 October 2020 to 25 January 2021 and was getting closer to its destination,the red planet,in search of answers to the cataclysmic climate change that occurred in Martian history.Both the escape of the Martian atmosphere and the loss of surface water were firmly influenced by solar activities.Tianwen-1 provided a unique chance to depict the solar wind streams between Earth and Mars during the minimum of Solar Cycle 25.During the three-month cruise phase of Tianwen-1,the solar wind flows were successively observed at Earth,Tianwen-1,and Mars.After the field of view correction and noise reduction,the solar wind velocity and density measured by Tianwen-1 show good agreement with those at Earth and Mars.The results indicate that the performance of the ion analyzer onboard the Tianwen-1 orbiter is reliable and stable.It is worth looking forward to the joint observations of ion escape with other Mars probes in the following Martian years. | Kai FAN Limei YAN Yong WEI Aibing ZHANG Linggao KONG Markus FRÄNZ Fei HE Lihui CHAI Chongjing YUAN Yuqi WANG Jun ZHONG Zhaojin RONG Zhonghua YAO Yongxin PAN Jun CUI Jiansen HE Wenya LI Binbin TANG Chi WANG | 2022 | Science China Earth Sciences2022，65，4： | 2 |
| 6 | Electrochromic-Induced Rechargeable Aqueous Batteries: An Integrated Multifunctional System for Cross-Domain Applications显示文摘Multifunctional electrochromic-induced rechargeable aqueous batteries(MERABs) integrate electrochromism and aqueous ion batteries into one platform, which is able to deliver the conversion and storage of photo-thermal-electrochemical sources.Aqueous ion batteries compensate for the drawbacks of slow kinetic reactions and unsatisfied storage capacities of electrochromic devices. On the other hand, electrochromic technology can enable dynamically regulation of solar light and heat radiation. However,MERABs still face several technical issues, including a trade-off between electrochromic and electrochemical performance, low conversion efficiency and poor service life. In this connection, novel device configuration and electrode materials, and an optimized compatibility need to be considered for multidisciplinary applications. In this review,the unique advantages, key challenges and advanced applications are elucidated in a timely and comprehensive manner. Firstly, the prerequisites for effective integration of the working mechanism and device configuration, as well as the choice of electrode materials are examined. Secondly, the latest advances in the applications of MERABs are discussed, including wearable, self-powered, integrated systems and multisystem conversion. Finally, perspectives on the current challenges and future development are outlined, highlighting the giant leap required from laboratory prototypes to large-scale production and eventual commercialization. | Qi Zhao Zhenghui Pan Binbin Liu Changyuan Bao Ximeng Liu Jianguo Sun Shaorong Xie Qing Wang John Wang Yanfeng Gao | 2023 | Nano-Micro Letters2023，15，6： | 2 |
| 7 | An overview of buckling and ultimate strength of spherical pressure hull under external pres- sure 显示文摘 | PAN Binbin | 2010 | Marine Structures2010，23，： | 1 |
| 8 | An anti-freezing biomineral hydrogel of high strain sensitivity for artificial skin applications显示文摘Mineral hydrogels have caught a lot of attention for their strong competency as artificial skin-like materials.Nonetheless,it remains a great difficulty in fulfilling in one hydrogel system a range of key functionalities that are needed for practical artificial skin applications,i.e.,to be biocompatible,strain-sensitive,ion-conductive,elastic and robust,anti-swelling,and anti-freezing.Here we present a such type of versatile hydrogel that is not only capable to deliver all the above-mentioned key functionalities but also highly stable.This novel hydrogel is constructed by introducing a gelatinous and amorphous multi-ionic biomineral(denoted as Mg-ACCP,containing Mg^(2+),Ca^(2+),CO_(3)^(2−),and PO_(4)^(3−))into the network of biocompatible polyvinyl alcohol(PVA)and sodium alginate(SA).The presence of Mg^(2+)and PO_(4)^(3−)in this hydrogel helps prohibit the crystallization of the biominerals,leading to significantly improved stability.The hydrogel thus obtained delivers excellent mechanical performance due to the chelation between the mineral ions and the organic matrix,and high sensitivity even to subtle pressure and strain applied,such as slight finger bending and gentle tapping.Furthermore,the novel hydrogel features high ionic conductivity,high resistance to swelling,and extraordinary anti-freezing property,holding great promise for applications in different practical scenarios,particularly in aqueous or cold environments. | Junda Shen Peng Du Binbin Zhou Guobin Zhang Xinxue Tang Jie Pan Bo Li Jingyang Zhang Jian Lu Yang Yang Li | 2022 | Nano Research2022，15，7： | 1 |
| 9 | An overview of buckling and ultimate strength of spherical pressure hull under external pressure显示文摘 | Binbin Pan Weicheng Cui | 2010 | Marine Structures2010，，3： | 1 |
| 10 | Sandwich-structured nanocomposite constructed by fabrication of exfoliation a-ZrP nanosheets and cobalt porphyrin utilized for electrocatalytic oxygen reduction显示文摘 | PAN Binbin MA Juanjuan ZHANG Xiaobo | 2016 | Microporous and Mesoporous Materials2016，223，11： | 1 |
| 11 | New Gene Variants Associated with the Risk of Chronic HBV Infection显示文摘Some patients with chronic hepatitis B virus(HBV)infection failed to clear HBV,even persistently continue to produce antibodies to HBV.Here we performed a two stage genome wide association study in a cohort of Chinese patients designed to discover single nucleotide variants that associate with HBV infection and clearance of HBV.The first stage involved genome wide exome sequencing of 101 cases(HBsAg plus anti-HBs positive)compared with 102 control patients(antiHBs positive,HBsAg negative).Over 80%of individual sequences displayed 209 sequence coverage.Adapters,uncertain bases[10%or low-quality base calls([50%)were filtered and compared to the human reference genome hg19.In the second stage,579 chronic HBV infected cases and 439 HBV clearance controls were sequenced with selected genes from the first stage.Although there were no significant associated gene variants in the first stage,two significant gene associations were discovered when the two stages were assessed in a combined analysis.One association showed rs506121-“T”allele[within the dedicator of cytokinesis 8(DOCK8)gene]was higher in chronic HBV infection group than that in clearance group(P=0.002,OR=0.77,95%CI[0.65,0.91]).The second association involved rs2071676—A allele within the Carbonic anhydrase(CA9)gene that was significantly elevated in chronic HBV infection group compared to the clearance group(P=0.0003,OR=1.35,95%CI[1.15,1.58]).Upon replication these gene associations would suggest the influence of DOCK8 and CA9 as potential risk genetic factors in the persistence of HBV infection. | Mengjie Fan Jing Wang Sa Wang Tengyan Li Hong Pan Hankui Liu Huifang Xu Daria V.Zhernakova Stephen J.O’Brien Zhenru Feng Le Chang Erhei Dai Jianhua Lu Hongli Xi Yanyan Yu Jianguo Zhang Binbin Wang Zheng Zeng | 2020 | Virologica Sinica2020，35，4： | 1 |
| 12 | An overview of buckling and ultimate strength of spherical pressure hull under external pressure 显示文摘 | PAN Binbin CUI Weicheng | 2010 | Marine Structures2010，，23： | 1 |
| 13 | Experimen- tal verification of the new ultimate strength equation of spher- ical pressure hulls显示文摘 | PAN Binbin CUI Weicheng SHEN Yunsheng | 2012 | Marine Structures2012，，5： | 1 |
| 14 | Nonlinear nonnegative matrix factorization based on Mercer kernel construction显示文摘 | PAN Binbin LAI Jianhuang CHEN Wensheng | 2011 | Pattern Recognition2011，44，1011： | 1 |
| 15 | Macrophage membrane-biomimetic adhesive polycaprolactone nanocamptothecin for improving cancer-targeting efficiency and impairing metastasis显示文摘The recent remarkable success and safety of mRNA lipid nanoparticle technology for producing severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)vaccines has stimulated intensive efforts to expand nanoparticle strategies to treat various diseases.Numerous synthetic nanoparticles have been developed for pharmaceutical delivery and cancer treatment.However,only a limited number of nanotherapies have enter clinical trials or are clinically approved.Systemically administered nanotherapies are likely to be sequestered by host mononuclear phagocyte system(MPS),resulting in suboptimal pharmacokinetics and insufficient drug concentrations in tumors.Bioinspired drug-delivery formulations have emerged as an alternative approach to evade the MPS and show potential to improve drug therapeutic efficacy.Here we developed a biodegradable polymer-conjugated camptothecin prodrug encapsulated in the plasma membrane of lipopolysaccharide-stimulated macrophages.Polymer conjugation revived the parent camptothecin agent(e.g.,7-ethyl-10-hydroxy-camptothecin),enabling lipid nanoparticle encapsulation.Furthermore,macrophage membrane cloaking transformed the nonadhesive lipid nanoparticles into bioadhesive nanocamptothecin,increasing the cellular uptake and tumor-tropic effects of this biomimetic therapy.When tested in a preclinical murine model of breast cancer,macrophage-camouflaged nanocamptothecin exhibited a higher level of tumor accumulation than uncoated nanoparticles.Furthermore,intravenous administration of the therapy effectively suppressed tumor growth and the metastatic burden without causing systematic toxicity.Our study describes a combinatorial strategy that uses polymeric prodrug design and cell membrane cloaking to achieve therapeutics with high efficacy and low toxicity.This approach might also be generally applicable to formulate other therapeutic candidates that are not compatible or miscible with biomimetic delivery carriers. | Kangkang Ying Yifeng Zhu Jianqin Wan Chenyue Zhan Yuchen Wang Binbin Xie Peirong Xu Hongming Pan Hangxiang Wang | 2023 | Bioactive Materials2023，，2： | 1 |
| 16 | Surface promotion of copper nanoparticles with alumina clusters derived from layered double hydroxide accelerates CO_(2)reduction to ethylene in membrane electrode assemblies显示文摘Electrochemical CO_(2)reduction has the vast potential to neutralize CO_(2)emission and valorizes this greenhouse gas into chemicals and fuels under mild conditions.Its commercial realization hinges on catalyst innovation as well as device engineering for enabling reactions at industrially relevant conditions.Copper has been widely examined for the selective production of multicarbon chemicals particularly ethylene,while there is still a substantial gap between the expected and the attainable.In this work,we report that the surface promotion of copper with alumina clusters is a viable strategy to enhance its electrocatalytic performance.AlOx-promoted Cu catalyst is derived from Cu-Al layered double hydroxide nanosheets after alkali etching and cathodic conversion.It can catalyze CO_(2)to ethylene and multicarbon products with great selectivity and stability far superior to pristine copper in both an H-cell and a zero-gap membrane electrode assembly(MEA)electrolyzer.The surface promotion effect is understood via computational simulations showing that alumina clusters can stabilize key reaction intermediates(*COOH and*OCCOH)along the reaction pathway. | Jie Zhang Xinnan Mao Binbin Pan Jie Xu Xue Ding Na Han Lu Wang Yuhang Wang Yanguang Li | 2023 | Nano Research2023，16，4： | 1 |
| 17 | Electrospun polypyrrole-coated polycaprolactone nanoyarn nerve guidance conduits for nerve tissue engineering显示文摘Nerve guidance conduits (NGCs) can provide suitable microenvironment for nerve repair and promote the proliferation and migration of Schwann cells (SCs). Thus, we developed nerve guidance conduits (NGCs) with polypyrrole-coated poly-caprolactone nanoyarns (PPy-PCL-NYs) as fillers in this study. PCL-NYs with the oriented structure were prepared with a double-needle electrospinning system and then PPy was coated on PCL-NYs via the in situ chemical polymerization. Subsequently, PCL nanofibers were collected around nanoyarns by the conventional electrospinning process as the outer layer to obtain PPy-PCL-NY nerve guidance conduits (PPy-PCL- NY NGCs). PPy-PCL-NYs were analyzed by SEM, FTIR and XPS. Results showed that PPy was homogeneously and uniformly deposited on the surface of PCL-NY. Strain-stress curves and the Young’s modulus of PPy-PCL-NYs were investigated compared with those of non-coated PCL-NYs. Studies on biocompatibility with SCs indicated that PPy-PCL-NY NGCs were more conducive to the proliferation of SCs than PCL-NY NGCs. In summary, PPy-PCL-NY NGCs show the promising potential for nerve tissue engineering repair and regeneration. | Xin PAN Binbin SUN Xiumei MO | 2018 | Frontiers of Materials Science2018，12，4： | 1 |
| 18 | An overview of buckling and ultimate strength of spherical pressure hull under external pressure 显示文摘 | Pan Binbin Cui Weicheng | 2010 | Marine Structures2010，23，： | 1 |
| 19 | Adjusting the local solvation structures and hydrogen bonding networks for stable aqueous batteries with reduced cost显示文摘Exploring low-cost and effective approaches to extend the potentials of aqueous electrolytes is highly desired.Herein,it is found that the activity of H_(2)O in aqueous electrolytes could be intensively manipulated by introducing small urea and long-chain polyethylene glycol(PEG)molecules into Li TFSI-H_(2)O electrolyte systems without super salt concentration.The urea and PEG molecules could exclude partial coordinated H_(2)O out of the inner solvation shell of Li_(4) and reconstruct hydrogen-bonding network between H_(2)O and PEG molecules outside the solvation sheaths with restricted H_(2)O activity and extended electrochemical window.The bonding competitions in aqueous electrolytes and their correlation to the electrochemical performance of full cells are studied.When the occurrence probability of H_(2)O around Li_(4)is lower than 40%,stable cycling of 3.1 V LiMn_(2)O_(4)-Li_(4)Ti_(5)O_(12) full cell is achieved,showing 73%capacity retention after 200 cycles at 1 C rate in optimal electrolytes.This work provides new avenues to understand the role of H_(2)O and explore low-cost and effective approaches for the development of nextgeneration aqueous lithium-ion batteries. | Canfu Zhang Binbin Chen Haoran Cai Renzhi Huang Yingchun Liu Huilin Pan | 2022 | Journal of Energy Chemistry2022，31，5： | 0 |
| 20 | Application of a Nanostructured Composite Material Constructed by Self-Assembly of Titanoniobate Nanosheets and Cobalt Porphyrin to Electrocatalytic Reduction of Oxygen显示文摘 | Jinpeng Li Xiaobo Zhang Binbin Pan Jiasheng Xu Lin Liu Juanjuan Ma Min Yang Zhenye Zhang Zhiwei Tong | 2016 | Chinese Journal of Chemistry2016，34，10： | 0 |
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