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| 1 | Differential expression of serum miR-126,miR-141 and miR-21 as novel biomarkers for early detection of liver metastasis in colorectal cancer显示文摘Objective:MicroRNAs(miRNAs) have potential as diagnostic biomarkers in cancer.Evaluation of the association between miRNA expression patterns and early detection of liver metastasis in colorectal cancer(CRC) has not been reported.Methods:We investigated the expression of metastasis-associated miRs-31,335,206,141,126,200b,200c,21,Let7a,Let7b and Let7c in localized,liver-metastatic and other organ-metastatic CRC(OM-CRC).Expressions of target miRNAs in serum were evaluated in 116 consecutive localized CRC(L-CRC),72 synchronous liver-metastatic CRC(SLM-CRC) and 36 other OM-CRC by quantitative real-time PCR.Results:Seven of 11 tested miRNAs could be detected from serum.Four miRNAs,miR-126,Let-7a,miR-141 and miR-21 were identified as metastasis-associated miRNAs.Compared with L-CRC,significant upregulated expression was observed for miR-141 and miR-21 in SLM-CRC and OM-CRC,down-regulated expression was observed for miR-126 in SLM-CRC and OM-CRC,and up-regulated expression of Let-7a in OM-CRC.The receiver operating characteristic(ROC) curve showed serum miR-126 had a cut-off [log 10 relative quantity(log 10 RQ)=–0.2005] with 77.78% sensitivity and 68.97% specificity with an area under curve(AUC) of 0.7564,miR-141 had a cut-off(log 10 RQ=–0.2285) with 86.11% sensitivity and 76.11% specificity with an AUC of 0.8279,and miR-21 had a cut-off(log 10 RQ=–0.1310) with 73.61% sensitivity and 66.38% specificity with an AUC of 0.7479.Conclusions:We identified liver metastasis-associated miRNAs,suggesting serum miR-126,miR-141 and miR-21 may be novel biomarkers for clinical diagnosis of early stage liver-metastatic CRC. | Jie Yin Zhigang Bai Jianning Song Yun Yang Jin Wang Wei Han Jun Zhang Hua Meng Xuemei Ma Yao Yang Tingting Wang Weirong Li Zhongtao Zhang | 2014 | Chinese Journal of Cancer Research2014，26，1： | 22 |
| 2 | Geochemical and isotopic characteristics of volcanic rocks from the northern East China Sea shelf margin and the Okinawa Trough显示文摘Volcanic rocks both from the northern East China Sea (NECS) shelf margin and the northern Okinawa Trough are subalkaline less aluminous,and lower in High Field Strength Elements (HFSE).These rocks are higher in Large Ion Lithophile Elements (LILE),thorium and uranium contents,positive lead anomalies,negative Nb-Ta anomalies,and enrichment in Light Rare Earth Elements (LREE).Basalts from the NECS shelf margin are akin to Indian Ocean Mid-Ocean Ridge Basalt (MORB),and rhyolites from the northern Okinawa Trough have the highest 207 Pb/ 204 Pb and 208 Pb/ 204 Pb ratios.The NECS shelf margin basalts have lower 87 Sr/ 86 Sr ratios,ε N d and σ 18 O than the northern Okinawa Trough silicic rocks.According to 40 K– 40 Ar isotopic ages of basalts from the NECS shelf margin,rifting of the Okinawa Trough may have been active since at least 3.65–3.86 Ma.The origin of the NECS shelf margin basalt can be explained by the interaction of melt derived from Indian Ocean MORB-like mantle with enriched subcontinental lithosphere.The basalts from both sides of the Okinawa Trough may have a similar origin during the initial rifting of the Okinawa Trough,and the formation of basaltic magmas closely relates to the thinning of continental crust.The source of the formation of the northern Okinawa Trough silicic rocks was different from that of the middle Okinawa Trough,which could have been generated by the interaction of basaltic melt with an enriched crustal component.From the Ryukyu island arc to East China,the Cenozoic basalts have apparently increasing trends of MgO contents and ratios of LREE to Heavy Rare Earth Elements (HREE),suggesting that the trace element variabilities of basalts may have been influenced by the subduction of the Philippine Sea plate,and that the effects of subduction of the Philippine Sea plate on the chemical composition of basaltic melts have had a decreasing effect from the Ryukyu island arc to East China. | ZENG Zhigang YU Shaoxiong WANG Xiaoyuan FU Yongtao YIN Xuebo ZHANG Guoliang WANG Xiaomei CHEN Shuai | 2010 | Acta Oceanologica Sinica2010，29，4： | 19 |
| 3 | Burden of colorectal cancer in China, 1990-2017: Findings from the Global Burden of Disease Study 2017显示文摘Objective: Our goal is to analyze the trend of colorectal cancer(CRC) regarding the death, incidence and prevalence rates over time, and to provide epidemiological knowledge basis for health policy revision by comparing data about fatal outcomes of CRC in 2017 to those data in 1990, which was extracted from the Global Burden of Disease(GBD).Methods: The time trend and changes of CRC burden from 1990 to 2017 were measured by using the methods and results from the Institute for Health Metrics and Evaluation(IHME) GBD 2017, based on the rates of death,incidence and prevalence.Results: The death rate of CRC is 13.24/100,000, accounting for 1.79% of total deaths in China in 2017. In1990, CRC ranked 21 st in all causes of death in China compared to its 11 th ranking in 2017. The death, incidence and prevalence rate of CRC were standardized by the age scale of the global population in 2010, the change of standardized death rate of CRC was not significant, from 9.33/100,000 in 1990 to 10.10/100,000 in 2017. The standardized incidence rate of CRC significantly increased from 12.18/100,000 in 1990 to 22.42/100,000 in 2017.The standardized prevalence rate of CRC significantly increased from 44.55/100,000 in 1990 to 118.40/100,000 in2017. The trend of the prevalence rate in both genders grow higher in 2017 compared to the 1990, resulting in141.6%, 209.8% and 189.0% for the studied three age groups(15-49, 50-69 and 70+ years old), respectively. The death rate increased in the age groups of 50-69 and 70+ years in both genders(8.6% and 31.0% respectively), in contrast to a decrease of death rate in the age group of 15-49 years old(-10.8%).Conclusions: China experienced a stunning increase in terms of incidence and prevalence rate of CRC from1990 to 2017. To decrease the burden of CRC, prevention and management of known risk factors should be promoted through national polices. | Jie Yin Zhigang Bai Jun Zhang Zhi Zheng Hongwei Yao Pengpeng Ye Jun Li Xin Gao Zhongtao Zhang | 2019 | Chinese Journal of Cancer Research2019，31，3： | 16 |
| 4 | Formation of Fe-oxyhydroxides from the East Pacific Rise near latitude 13°N:Evidence from mineralogical and geochemical data显示文摘The mineralogical and geochemical characteristics of Fe-oxyhydroxide samples from one dredge station (long. 103°54.48'W, lat. 12°42.30'N, water depth 2655 m) on the East Pacific Rise near lat 13°N were analyzed by XRD, ICP-AES, and ICP-MS. Most Fe-oxyhydroxides are amorphous, with a few sphalerite microlites. In comparison with Fe-oxyhydroxides from other fields, the variable ranges in the chemical composition of Fe-oxyhydroxide samples are very narrow; their Fe, Si, and Mn contents were 39.90%, 8.92%, and 1.59%, respectively; they have high Cu (0.88%―1.85%) and Co (65×10?6―704×10?6) contents, and contain Co+Cu+Zn+Ni> 1.01%. The trace-element (As, Co, Ni, Cu, Zn, Ba, Sr) and major-element (Fe, Ca, Al, Mg) contents of these samples are in the range of hydrothermal sulfide from the East Pacific Rise near 13°N, reflecting that this type of Fe-oxyhydroxide constitutes a secondary oxidation product of hydrothermal sulfide. The Fe-oxyhydroxide samples from one dredge station on the East Pacific Rise near 13°N are lower in ΣREE (5.44×10?6―17.01×10?6), with a distinct negative Ce anomaly (0.12 ― 0.28). The Fe-oxyhydroxide samples have similar chondrite-normalized rare-earth-element (REE) patterns to that of seawater, and they are very different from the REE composition characteristics of hydrothermal plume particles and hydrothermal fluids, showing that the REEs of Fe-oxyhydroxide are a major constituent of seawater and that the Fe-oxyhydroxides can become a sink of REE from seawater. The quick settling of hydrothermal plume particles resulted in the lower REE content and higher Mn content of these Fe-oxyhydroxides, which are captured in part of the V and P from seawater by adsorption. The Fe-oxyhydroxides from one dredge station on the East Pacific Rise near 13°N were formed by secondary oxidation in a low temperature, oxygenated environment. In comparison with the elemental (Zn, Cd, Pb, Fe, Co, Cu) average content of hydrothermal sulfide samples from the East Pacific Rise near 13°N, the Zn, Cd, and Pb contents of the Fe-oxyhydroxides are lower, and their Fe, Co, and Cu contents are higher. | ZENG ZhiGang WANG XiaoYuan ZHANG GuoLiang YIN XueBo CHEN DaiGeng WANG XiaoMei | 2008 | Science China Earth Sciences2008，51，2： | 12 |
| 5 | OsMADS16 Genetically Interacts with OsMADS3 and OsMADS58 in Specifying Floral Patterning ~in Rice显示文摘瑞斯(Oryza sativa ) 有贡献谷物产量的唯一的花的模式。然而,在米饭位于花的机关身份的说明下面的分子的机制,特别地在花的 homeotic 基因之中的相互作用,遗体糟糕理解。这里,我们证明花的 homeotic 基因 OsMADS16 (也叫的 SUPERWOMAN1, SPW1, B 班基因) 和在指定花的机关 patterning 的米饭 C 班基因 OsMADS3 和 OsMADS58 的行为。OsMADS16 和二 C 班基因在第三个锭盘创始人房间有一个重叠表示模式。与单个异种相比, spw1-1 osmads3-4 和 spw1-1 osmads58 加倍异种在花以内展出像颖的机关的另外的锭盘,特别地,六像颖的结构的额外的锭盘在野类型的雄蕊的位置形成了。这些宫外的像颖的结构被显示用标记基因通过细胞的观察并且在 situ 杂交分析有 palea 身份。我们的结果建议 B 班和 C 班基因在在花的分裂组织以内压制不确定的生长起一个关键作用,特别地 whorl-3 primordia。我们也假设那,与以前的假设相对照,在米饭的专业化小穗状花小穗机关, palea,在 eudicots 的萼片的对应物,和词根对苞相应。 | Dapeng Yun Wanqi Liang Ludovico Dreni Changsong Yin Zhigang Zhou Martin M. Kater Dabing Zhang | 2013 | Molecular Plant2013，6，3： | 11 |
| 6 | Deep Fractionation of Clinopyroxene in the East Pacific Rise 13°N:Evidence from High MgO MORB and Melt Inclusions显示文摘从东方太平洋的海中央山脉暗岩(MORB ) 升起(EPR ) 13 ° N 为专业和踪迹元素被分析,哪个表演一个连续演变趋势。积极姆戈·艾尔 2 O 3 和否定 MgO Sc 关系表明斜长石和橄榄石的 cotectic 结晶化,它与斜长石和橄榄石斑晶和 clinopyroxene 斑晶的缺席的存在存在。然而, clinopyroxene 的分别被 MgO 和 CaO 的积极关联证明。因此, MORB 样品被相信显示出“ clinopyroxene 悖论”。最高忍受镁的 MORB 样品 E13 3B (MgO =9.52%) 在不同压力与 COMAGMAT 为等压的结晶化被建模。观察 CaO/Al 2 O 3 比率能在压力 >4 ± 1 kbar 仅仅由部分结晶化从 E13 3B 被导出,它要求 clinopyroxene 结晶化并且不与加在岩浆房间的斜长石的橄榄石的 cotectic 结晶化一致(在压力 ∼1 kbar ) 。melt 包括的起始的作文,能代表潜在的父母岩浆,被为陷阱以后的结晶化(PEC ) 改正重建。模仿的结晶化起始融化包括也生产观察 CaO/Al 2 仅仅在 >4 ± 1 kbar, clinopyroxene 在参加结晶化的 O 3 比率。MORB 岩浆在更低的外壳中经历了 clinopyroxene 分别,这被建议,在并且在莫霍转变地区下面。MORB 岩浆在 >4 ± 1 kbar 从 clinopyroxene+plagioclase+olivine 结晶化经历了转变到主要在 <1 kbar 的 olivine+plagioclase 结晶化,它贡献“ clinopyroxene 悖论”的解释。 | ZHANG Guoliang ZENG Zhigang YIN Xuebo WANG Xiaoyuan CHEN Daigeng | 2009 | Acta Geologica Sinica(English Edition)2009，83，2： | 7 |
| 7 | Mineralogical and micromorphological characteristics of Si-Fe-Mn oxyhydroxides from the PACMANUS hydrothermal field, Eastern Manus Basin显示文摘The mineralogical and micromorphological characteristics of Si-Fe-Mn oxyhydroxides from the dacite-hosted PACMANUS hydrothermal field were analyzed.The samples are poorly crystallized Si-Fe-Mn oxyhydroxides with minor birnessite, todorokite, nontronite, goethite, and opal-A.There are some microtextures which are rather like fossil microbes such as the filamentous silica and the hollow pipes.Flakes of nontronite crystals are found either forming a honeycomb texture or distrib- uted on the surface of the hollow pipes.Nontronite is the product precipitated from low-temperature hydrothermal fluids, and microbes may play a role in its formation.Si-Fe-Mn oxyhydroxides have two kinds of nuclei: Si-Mn nuclei and Si nuclei, both enveloped by the similar Si-Fe outer layer, existing in the rod-shaped oxyhydroxide and spheroidal oxyhydroxide, respectively.In the Si-Mn nuclei, the concentration of SiO2 is between 39.32 wt% and 86.31 wt%, and MnO concentration is between 4.97 wt% and 27.01 wt%, but Fe2O3 concentration is very low (0.54 wt%-3.43 wt%).In the Si nucleus the concentration of SiO2 is 90.17 wt%, but concentration of MnO and Fe2O3 are low, with 0.06 wt% and 3.47 wt%, respectively.The formation of the Si-Mn nucleus is closely related to microbes, whereas the Si nucleus is of inorganic origin. | ZENG ZhiGang CHEN Shuai WANG XiaoYuan OUYANG HeGen YIN XueBo LI ZhaoXue | 2012 | Science China Earth Sciences2012，55，12： | 7 |
| 8 | Rare earth elements in hydrothermal fluids from Kueishantao,off northeastern Taiwan: Indicators of shallow-water,sub-seafloor hydrothermal processes显示文摘The rare earth element(REE)geochemistry of hydrothermal vent systems has been investigated intensively,but few studies have been carried out on marine shallow-water hydrothermal systems like that at Kueishantao.Here we present novel data sets of REE in hydrothermal fluids from Kueishantao,off northeastern Taiwan.The total REE(REE)concentrations of yellowish fluids are similar to those of whitish fluids,813–1212 ng/L,and are significantly higher than that of ambient seawater.The yellowish fluids have chondrite-normalized REE(REEN)distribution patterns with slight convex-downward curvatures at Eu;and the REE patterns of the whitish fluids are smooth at Eu,which is related to the lower temperature and more oxidizing conditions.The Kueishantao hydrothermal fluids are slightly enriched in light REE(La-Nd)relative to the heavy REE(Gd-Lu).The behaviors of REE in both yellowish and whitish fluids are affected by the short time of water-rock interaction.The REE distributions in the yellowish fluids are also affected by very low pH(2.81 and 2.29),boiling of the fluid and precipitation of native sulfur.In the whitish fluids,adsorption by small particles and formation of REE-chloride complexes has played a role in the distribution of REE. | WANG XiaoYuan ZENG ZhiGang CHEN Shuai YIN XueBo CHEN Chen-Tung Arthur | 2013 | Chinese Science Bulletin2013，58，32： | 7 |
| 9 | Component characteristics of organic matter in hydrothermal barnacle shells from Southwest Indian Ridge显示文摘In 2008–2009,hydrothermal barnacle and sediment samples were collected from the Southwest Indian Ridge during a survey of the China Ocean Mineral Resources R&D Association(COMRA).Samples were analyzed by gas chromatography-mass spectrometer(GC-MS),revealing the main organic constituents of hydrothermal barnacle and sediment to be fatty acids and alkylbenzenes.N-alkanes which possessed obvious even carbon advantage were also detected in hydrothermal sediment.The high concentrations of aromatic compounds might be the result of macromolecular thermal alteration.Microorganism in the submarine hydrothermal ecosystem,especially those related to sulfur metabolism,might be the source of the high concentrations of fatty acids detected in these samples.In high temperature and high pressure hydrothermal environments,n-alkanes which possessed obvious even carbon advantage might originate from thermal alteration of carboxylic acids and other lipid compounds. | HUANG Xin ZENG Zhigang CHEN Shuai YIN Xuebo WANG Xiaoyuan ZHAO Huijing YANG Baoju RONG Kunbo MA Yao | 2013 | Acta Oceanologica Sinica2013，32，12： | 6 |
| 10 | Hydrothermal alteration of plagioclase microphenocrysts and glass in basalts from the East Pacific Rise near 13°N: An SEM-EDS study显示文摘The interactions of seafloor hydrothermal fluid with igneous rocks can result in leaching elements from the rocks,creating potential ore-forming fluids and influencing the chemical compositions of near-bottom seawater.The hydrothermal alteration of plagioclase microphenocrysts and basaltic glass in the pillow basalts from one dredge station(103°57.62′′W,12°50.55′N,water depth 2480 m)on the East Pacific Rise(EPR)near 13°N were analyzed using a scanning electron microscope(SEM)and energy dispersive X-ray spectrometry(EDS).The results show that the edges of the plagioclase microphenocrysts and the basaltic glass fragments are altered but the pyroxene and olivine microphenocrysts in the interior of the pillow basalts appear to be unaffected by the hydrothermal fluids.In addition,our results show that the chemical alteration at the rims of the plagioclase microphenocrysts and the edges of basaltic glass fragments can be divided into separate types of alteration.The chemical difference in hydrothermal alteration of the plagioclase microphenocrysts and the basaltic glass indicate that different degrees of hydrothermal fluid-solid phase interaction have taken place at the surface of the pillow basalts.If the degree of hydrothermal fluid-solid phase interaction is relatively minor,Si,Al,Ca and Na diffuse from the inside of the solid phase out and as a result these elements have a tendency to accumulate in the edge of the plagioclase microphenocrysts or basaltic glass.If the degree of hydrothermal fluid-solid phase interaction is relatively strong,Si,Al,Ca and Na also diffuse from the inside of solid phase out but these elements will have a relatively low concentration in the edge of the plagioclase microphenocrysts or basaltic glass.Based on the chemical variation observed in the edges of plagioclase microphenocrysts and basaltic glass,we estimate that the content of Si,Al and Fe in the edges of plagioclase microphenocrysts can have a variation of 10.69%,17.59%and 109%,respectively.Similarly,the Si,Al and Fe concentrations in the edges of basaltic glass can have a variation of 9.79%,16.30%and 37.83%,respectively,during the interaction of hydrothermal fluids and seafloor pillow basalt. | ZENG ZhiGang QI HaiYan CHEN Shuai YIN XueBo LI ZhaoXue | 2014 | Science China Earth Sciences2014，57，7： | 5 |
| 11 | Adipocyte-derived SFRP5 inhibits breast cancer cells migration and invasion through Wnt and epithelial-mesenchymal transition signaling pathways显示文摘Objective:Obesity is closely associated with metastasis in breast cancer patients.Secreted frizzled-related protein 5(SFRP5),one of the novel adipokines with anti-inflammatory properties,is associated with obesity.This study aims to study the role of SFRP5 in the crosstalk between obesity and breast cancer metastasis and identify the underlying mechanism.Methods:3T3-L1 pre-adipocytes were differentiated to mature adipocytes and a hypertrophic adipocyte model was induced with palmitic acid(PA).Cell motility was measured in MDA-MB-231 and MCF-7 breast cancer cells co-cultured with adipocytes conditioned medium(CM)with or without SFRP5 protein.Wnt and epithelialmesenchymal transition(EMT)signal pathways were investigated by western blot.Circulating SFRP5 level in 218 breast cancer patients and the association with clinicopathologic characteristics of breast cancer were further determined.Online databases ENCORI and PREDICT Plus were used to exam the link between SFRP5 and prognosis.Results:Reduced SFRP5 level was detected in the hypertrophic adipocyte model.Recombinant SFRP5 protein inhibited MDA-MB-231 and MCF-7 cells invasion and migration induced by PA-treated adipocyte CM,and SFRP5 inhibition by specific antibody reversed the effect of SFRP5.Furthermore,SFRP5 significantly inhibited Wnt and downstream EMT in breast cancer cells.Low circulating SFRP5 level correlated with body mass index(BMI),lymph node(LN)metastasis,TNM stage and high Ki67 expression in breast cancer patients.Increased SFRP5 level was associated with favorable predicted survival.Kaplan-Meier curves showed high SFRP5 level in tumor tissue was associated with better outcome of breast cancer patients.Conclusions:Our findings demonstrated SFRP5 is a vital adipokine that mediates the crosslink between obesity and the metastatic potential of breast cancer.Promotion of SFRP5 expression in the adipose microenvironment may represent a novel approach for preventing breast cancer metastasis. | Wenzhong Zhou Chunmiao Ye Liang Li Liyuan Liu Fei Wang Lixiang Yu Fei Zhou Yujuan Xiang Yongjiu Wang Gengshen Yin Zhongbing Ma Qinye Fu Qiang Zhang Dezong Gao Shuya Huang Zhigang Yu | 2020 | Chinese Journal of Cancer Research2020，32，3： | 5 |
| 12 | Fe-Si-Mn-Oxyhydroxide Encrustations on Basalts at East Pacific Rise near 13°N:An SEM-EDS Study显示文摘Fe-Si-Mn-oxyhydroxide encrustations at the East Pacific Rise(EPR) near 13°N were analyzed using the scanning electron microscope(SEM) with an energy dispersive spectrometer(EDS). These encrustations are mainly composed of amorphous FeSi-Mn-oxyhydroxides forming laminated, spherical, porous aggregates with some biodetritus, anhydrite, nontronite, and feldspar particles. Anhydrite particles and nontronite crystals in the Fe-Si-Mn-oxyhydroxide encrustations imply that the Fe-Si-Mn- oxyhydroxide may have formed under relatively low- to high-temperature hydrothermal conditions. The Fe-Si-Mn-oxyhydroxide encrustations on pillow basalts are 1–2 mm thick. The growth rate of ferromanganese crusts in the survey area suggests that these encrustations are an unlikely result of hydrogenic deposition alone having a hydrothermal and(Fe/Mn ratio up to 7.7 and Fe/(Fe+Mn+Al) ratio exceeding 0.78) hydrogenic origin(0.22 Fe/Mn ratio close to the mean value of 0.7 for open-ocean seamount crusts). The varying Fe/Mn ratios indicate that the Fe-Si-Mn-oxyhydroxide encrustations have formed through several stages of seafloor hydrothermalism. It is suggested that, at the initial formation stage, dense Fe-Si-oxyhydroxides with low Mn content deposit from a relatively reducing hydrothermal fluid, and then the loose Fe-Si-Mn-oxyhydroxides deposit on the Fe-Si-oxyhydroxides. As the oxidation degree of hydrothermal fluid increases and Si-oxide is inhibited, Mn-oxide will precipitate with Fe-oxyhydroxides. | WANG Xiaoyuan ZENG Zhigang QI Haiyan CHEN Shuai YIN Xuebo YANG Baoju | 2014 | Journal of Ocean University of China2014，13，6： | 5 |
| 13 | Abundance and Distribution of Fatty Acids in Sediments of the South Mid-Atlantic Ridge显示文摘Sediment samples obtained from the South Mid-Atlantic Ridge were studies by gas chromatography-mass spectrometer(GC-MS) for the abundance and distributions of total fatty acids(TFAs). Approximately 34 fatty acids were identified, with the chain-lengths ranging from C12 to C30. The total concentrations of TFAs(∑TFA) ranged from 7.15 to 30.09 μg g-1 dry sediment, and ∑TFA was weakly correlated with bitumen content(R2 = 0.69). The ∑TFA of samples around hydrothermal areas were significantly higher than that of samples away from hydrothermal areas, indicating intense primary production and large biomass in the hydrothermal areas, and suggesting a close relationship between hydrothermal activity and ∑TFA of samples. The characteristics of the TFA composition in the present study are rich in monounsaturated fatty acids and lacking in polyunsaturated fatty acids, and the ratios between the concentrations of monounsaturated fatty acids and ΣTFAs in samples close to the hydrothermal areas, are about 0.8, but for samples far from the hydrothermal areas, they are only about 0.5. Several fatty acids(e.g., a/i C15:0 and C16:1ω7), which are signature biomarkers for sulfur-metabolizing bacteria, show the same distribution trend as ∑TFA of samples, further highlighting the close relationship between fatty acid content and hydrothermal activity and/or hydrothermal communities. The metabolic activities of hydrothermal communities, especially those of microorganisms, are likely the main source of fatty acids in samples. | HUANG Xin ZENG Zhigang CHEN Shuai YIN Xuebo WANG Xiaoyuan MA Yao YANG Baoju RONG Kunbo SHU Yunchao JIANG Tao | 2015 | Journal of Ocean University of China2015，14，2： | 4 |
| 14 | Tailoring interphase structure to enable high-rate, durable sodium-ion battery cathode显示文摘Na-based layered transition metal oxides with O_(3)-type structure have been considered to be promising cathodes for Na-ion batteries. However, the intrinsically limited Na-ion conductivity induced by the Otype Na-coordinate environment compromises their rate and cycle capability, hindering their practical application. Here, we report an interphase-structure tailoring strategy that improves the electrochemical properties of O_(3)-type layered cathodes achieved through surface coating and doping processes.Specifically, a Zr-doped interphase structure is designed in the model compound NaNi_(1/3)Mn_(1/3)Fe_(1/3)O_(2) using the ionic conductor Na_(3)Zr_(2)Si_(2)PO_(12) as the surface coating material and Zr-dopant provider. We discover that the modified NaNi_(1/3)Mn_(1/3)Fe_(1/3)O_(2)cathode shows a stable Na-storage structure as well as an enhanced rate/cycle capability. Combined with theoretical calculations, it is suggested that the superior electrochemical performances originate from the Zr-doped interphase structure, which has an enlarged Na layer spacing that forms favorable Na-ion diffusion channels. This work highlights a general material interface optimization method which opens a new perspective for fabricating high-performance electrodes for Na-ion batteries and beyond. | Na Li Shaofei Wang Enyue Zhao Wen Yin Zhigang Zhang Kang Wu Juping Xu Yoshihiro Kuroiwa Zhongbo Hu Fangwei Wang Jinkui Zhao Xiaoling Xiao | 2022 | Journal of Energy Chemistry2022，31，5： | 4 |
| 15 | New insights into the origin of the bimodal volcanism in the middle Okinawa Trough: not a basalt-rhyolite differentiation process显示文摘 | Yuxiang ZHANG Zhigang ZENG Shuai CHEN Xiaoyuan WANG Xuebo YIN | 2018 | Frontiers of Earth Science2018，12，2： | 4 |
| 16 | Investigation into the flotation response of refractory molybdenum ore to depressant mixtures:A case study显示文摘In this paper, bulk flotation followed by separation was investigated to concentrate purified molybdenite product from Jinduicheng molybdenum ores(Shanxi province, China). The bench scale tests mainly focussed on separation of molybdenite from other sulfide minerals using the new type of depressants.The effect of each single depressant, including organic depressant-modified dextrin(MD), P-Nokes reagent(PN) and sodium trithiocarbonate(ST), and their mixtures on galena, chalcopyrite and other sulfide ores, was examined in turn by changing the concentrations used in cleaner flotation tests. Closed circuit experiments were carried out under the optimal condition and satisfying recovery and grade of molybdenite concentrate could be achieved(86.294% and 53.157%, respectively). A potential reagent regime was developed, with more environmental friendly and more economical advantages due to the introduction of modified dextrin. | Yin Zhigang Sun Wei Liu Jiandong Hu Yuehua Guan Qingjun Zhang Chenhu Tang Honghu Guan Changping | 2016 | International Journal of Mining Science and Technology2016，26，6： | 4 |
| 17 | Great progress in developing 500 MHz single cell superconducting cavity in China显示文摘Superconducting cavities have been adopted in many kinds of accelerator facilities such as synchrotron radiation light source, hard X-ray free electron laser linac, colliders and energy recovery linacs (ERL). The 500 MHz superconducting cavities will be a candidate to be installed in the high current accelerators and high current ERLs for their large beam aperture, low higher order modes impedance and high current threshold value. This paper presents great progress in the whole sequence of developing 500 MHz superconducting cavity in China. It describes the first in-house successful development of 500 MHz single cell superconducting cavity including the deep-drawing of niobium half cells, electron beam wielding of cavity, surface preparations and vertical testing. The highest accelerating gradient of the fabricated cavity #SCD-02 higher than 10 MV/m was obtained while the quality factor was better than 4×108 at 4.2 K, which has reached the world level of the same kind of cavities. | LIU JianFei HOU HongTao MAO DongQing FENG ZiQiang MA ZhenYu LUO Chen ZHAO ShenJie ZHAO YuBin YU HaiBo YIN Bo ZHANG ZhiGang ZHENG Xiang LI Zheng | 2011 | Science China(Physics,Mechanics & Astronomy)2011，54，S2： | 4 |
| 18 | Periodical mixing of MORB magmas near East Pacific Rise 13°N: Evidence from modeling and zoned plagioclase phenocrysts显示文摘Thirty-six basalt samples from near East Pacific Rise 13°N are analyzed for major and trace elements. Different types of zoned plagioclase phenocrysts in basalts are also backscatter imaged, and major element profiles scanned and analyzed for microprobe. Basalts dredged from a restricted area have evolved to different extents (MgO=9.38wt%—6.76wt%). High MgO basalts are modeled for crystalliza-tion to MgO of about 7wt%, and resulted in the Ni contents (≈28 ppm) that are generally lower than that in observed basalts (>60 ppm). It suggests that low MgO basalts may have experienced more intensive magma mixing. High MgO (9.38wt%) basalt is modeled for self-'mixing-crystallization', and the high Ni contents in low MgO basalts can be generated in small scale and periodical self-mixing of new magma (high MgO). 'Mixing-crystallization' processes that low MgO magmas experienced accord with recent 226Ra/230Th disequilibria studies for magma residence time, in which low MgO magmas have experi-enced more circles of 'mixing-crystallization' in relatively longer residence time. Magma mixing is not homogeneous in magma chamber, however, low MgO magmas are closer to stable composition pro-duced by periodical 'mixing-crystallization', which is also an important reason for magma diversity in East Pacific Rise. Zoned plagioclase phenocrysts can be divided into two types: with and without high An# cores, both of which have multiple reversed An# zones, suggesting periodical mixing of their host magmas. Cores of zoned plagioclase in low MgO (7.45wt%) basalt differ significantly with their mantle in An#, but are similar in An# with microlite cores (products of equilibrium crystallization) in high MgO (9.38wt%) basalt, which further shows that plagioclase phenocryst cores in low MgO basalts may have formed in their parental magmas before entering into the magma chamber. | ZHANG GuoLiang ZENG ZhiGang YIN XueBo CHEN DaiGeng WANG XiaoYuan WANG XiaoMei | 2008 | Science China Earth Sciences2008，51，12： | 4 |
| 19 | Quantifying the effectiveness of SiO_2/Au light trapping nanoshells for thin film poly-Si solar cells显示文摘In order to enhance light absorption of thin film poly-crystalline silicon(TF poly-Si)solar cells over a broad spectral range, and quantify the effectiveness of nanoshell light trapping structure over the full solar spectrum in theory,the effective photon trapping flux(EPTF)and effective photon trapping efficiency(EPTE)were firstly proposed by considering both the external quantum efficiency of TF poly-Si solar cell and scattering properties of light trapping structures.The EPTF,EPTE and scattering spectrum exhibit different behaviors depending on the geometric size and density of nanoshells that form the light trapping layer.With an optimum size and density of SiO2/Au nanoshell light trapping layer,the EPTE could reach up to 40%due to the enhancement of light trapping over a broad spectral range,especially from 500 to 800 nm. | BAI YiMing 1 ,WANG Jun 2 ,CHEN NuoFu 1,3 ,YAO JianXi 1 ,YIN ZhiGang 3 ,ZHANG Han 3 , ZHANG XingWang 3 ,HUANG TianMao 3 ,WANG YanShuo 3 &YANG XiaoLi 3 1School of Renewable Energy Engineering,North China Electric Power University,Beijing 102206,China 2 National Engineering Research Center for Optoelectronic Devices,Institute of Semiconductors, Chinese Academy of Sciences,PO Box 912,Beijing 100083,China 3 Key Laboratory of Semiconductor Materials Science,Institute of Semiconductors, Chinese Academy of Sciences,PO Box 912,Beijing 100083,China | 2010 | Science China(Technological Sciences)2010，53，8： | 4 |
| 20 | Materials Experiment on Tiangong-2 Space Laboratory显示文摘During the China's Tiangong-2(TG-2) flight mission, the experiments of 18 kinds of material samples were conducted in space by using a Multiple Materials Processing Furnace(MMPF) mounted in the orbital module of the TG-2 space laboratory. After the experiments of 12 kinds of samples of the first and second batches were completed successfully, astronauts packed and brought them back to the ground by ShenzhouII spacecraft. By studying processing and formation on semiconductor and optoelectronics materials, metal alloys and metastable materials, functional single-crystal, micro-and nano-composite materials encapsulated in sample ampoules both in space and on Earth, we expect to explore some physical and chemical processes and mechanism of the materials formation that are normally obscured and therefore are difficult to study quantitatively on the ground due to the gravity-induced convection, to obtain the processing and synthesis technology for preparing high quality materials, and lead to the improvement and development of materials processing techniques on Earth, and also develop the experiment device and comprehensive ability for materials experiment in microgravity environment. This report briefly introduces the main points of each research work and preliminary comparative analysis results of 12 samples carried out by scientists undertaking research task. | LI Xiangyang LU Ye MENG Xiangjian WANG Jianlu WANG Reng CHEN Lidong HUA Zile LI Xiaoya SHI Jianlin LIU Jinfeng XU Guisheng WEI Bingbo XIE Wenjun YIN Zhigang ZHANG Xingwang JIANG Hongxiang LI Hong LUO Xinghong ZHANG Haifeng ZHAO Jiuzhou WANG Binbin PAN Mingxiang | 2018 | 空间科学学报2018，38，5： | 4 |
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