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| 1 | Hypoxic preconditioning attenuates hypoxia/reoxygenation-induced apoptosis in mesenchymal stem cells显示文摘目的: 间充质的干细胞(MSC ) 是心脏的代替治疗的一个有希望的候选人。然而,因为差的血供给, ischemia-reperfusion,和煽动性的因素,移植 MSC 的多数乐意地在移植以后被失去。我们试图在 MSC.Methods 的 hypoxia/reoxygenation-induced apoptosis 上学习组织缺氧 preconditioning ( HPC )的效果: MSC 的三代被划分成 6 个组包括正常的组, hypoxia-reoxygenation ( H/R )组, cyclosporine A ( CsA ),和 HPC 10 min , 20 min ,并且 30 min 组织。 apoptotic 索引,房间生存能力, mitochondrial 膜电位, Bcl-2 和 bax 的易位,细胞外的调整激酶(英皇家空军之阶级最低之兵), Akt ,组织缺氧可诱导的因素 1-alpha ,并且脉管的内皮生长因素( VEGF )在 H/R treatment.Results 以后被测试: HPC 减少了 apoptotic 索引并且增加了 H/R.Moreover 导致的生存能力, HPC 显著地稳定了 mitochondrial 膜电位在调整 Bcl-2 和 VEGF 表达式上面,并且增加了英皇家空军之阶级最低之兵和 Akt.As 的磷酸化积极控制, CsA 有象 HPC 的一样的函数,除了支持英皇家空军之阶级最低之兵和 Akt 磷酸化并且在调整 VEGF.Conclusion 上面: HPC 对 H/R 经由稳定 mitochondrial 膜电位导致的 MSC apoptosis 有保护的效果在调整 Bcl-2 和 VEGF 上面,并且支持英皇家空军之阶级最低之兵和 Akt phosphorylation.HPC 为新奇干细胞protective 策略的开发有含意。 | Jian-an WANG Tie-long CHEN Jun JIANG Heng SHI Chun GUI Rong-hua LUO Xiao-jie XIE Mei-xiang XIANG Xing ZHANG | 2008 | Acta Pharmacologica Sinica2008，29，1： | 25 |
| 2 | Acute Respiratory Distress Syndrome: Challenge for Diagnosis and Therapy显示文摘 | Chun Pan Ling Liu Jian-Feng Xie Hai-Bo Qiu | 2018 | Chinese Medical Journal2018，，10： | 22 |
| 3 | Laparoscopic radical cystectomy with orthotopic ileal neobladder in the female: report of 14 cases显示文摘背景膀胱癌是在中国的最普通的恶意的 urological 肿瘤。我们在场我们有在有到 2008 年 2月的从2003年2月的膀胱 carcinoma.Methods 的女病人的 orthotopic ileal neobladder 的 laparoscopic 激进分子囊切除术(纵向冗余码校验)的初步的经验和结果,有膀胱癌的 14 个女病人与 orthotopic ileal neobladder 经历了纵向冗余码校验。九个这些病人经历了子宫切除和卵巢切除术,和子宫和卵巢的附器的另外的 5 有的保藏。当需要时,标准双边的骨盆的 lymphadenectomy 被与子宫切除和卵巢切除术 laparoscopically 被完成的激进的囊切除术跟随。肿瘤被一 4-5 厘米移开更低的中线腹的切口,由 ileal neobladder 和 ureter-neobladder 的身体外的吻合的构造列在后面。neobladder 在在 14 个病人的吝啬的起作用的时间和血损失是的 laparoscope.Results 下面被吻合到尿道的树桩 350.2 分钟和 349.8 ml, respectively.Postoperative 复杂并发症在 1 个病人在 1 耐心、小袋阴道的管包括了 uretero 小袋 anastomotic 苛评。所有病人的后续时间从 3 ~ 60 个月,并且 12 个病人被跟随在上面为半年里的超过 6 个月和完成的频尿。一耐心的有的偶尔的白天尿不能自制和 2 有的夜间不能自制。经历了 hystectomy 和卵巢切除术的二个病人在一年以后有 voiding 困难,它被断断续续的 self-catheterization 对待。neobladder 和剩余尿的吝啬的体积分别地是 333.6 ml 和 31.2 ml。外科的边缘是为所有病人免费的肿瘤。一个病人有骨头转移并且死在有在女病人的 orthotopic ileal neobladder 的 operation.Conclusions 纵向冗余码校验以后的 11 个月是有低病态和可接受的 neobladder 功能的一个技术上可行、安全、微型侵略的过程。长期的后续被要求证实 neobladder 功能和 oncological 结果。 | LIN Tian-xin ZHANG Cai-xia XU Ke-wei HUANG Hai JIANG Chun HAN Jin-li YAO You-sheng GUO Zheng-hui XIE Wen-lian YIN Xin-bao HUANG Jian | 2008 | Chinese Medical Journal2008，，10： | 18 |
| 4 | H_2S Protecting against Lung Injury following Limb Ischemia-reperfusion by Alleviating Inflammation and Water Transport Abnormality in Rats显示文摘Objective To investigate the effect of H2 S on lower limb ischemia-reperfusion(LIR) induced lung injury and explore the underlying mechanism. Methods Wistar rats were randomly divided into control group, IR group, IR+ Sodium Hydrosulphide(NaHS) group and IR+ DL-propargylglycine(PPG) group. IR group as lung injury model induced by LIR were given 4 h reperfusion following 4 h ischemia of bilateral hindlimbs with rubber bands. NaHS(0.78 mg/kg) as exogenous H2 S donor and PPG(60 mg/kg) which can suppress endogenous H2 S production were administrated before LIR, respectively. The lungs were removed for histologic analysis, the determination of wet-to-dry weight ratios and the measurement of mRNA and protein levels of aquaporin-1(AQP1), aquaporin-5(AQP5) as indexes of water transport abnormality, and mRNA and protein levels of Toll-like receptor 4(TLR4), myeloid differentiation primary-response gene 88(MyD88) and p-NF-κB as indexes of inflammation. Results LIR induced lung injury was accompanied with upregulation of TLR4-Myd88-NF-κB pathway and downregulation of AQP1/AQP5. NaHS pre-treatment reduced lung injury with increasing AQP1/AQP5 expression and inhibition of TLR4-Myd88-NF-κB pathway, but PPG adjusted AQP1/AQP5 and TLR4 pathway to the opposite side and exacerbated lung injury. Conclusion Endogenous H2 S, TLR4-Myd88-NF-κB pathway and AQP1/AQP5 were involved in LIR induced lung injury. Increased H2 S would alleviate lung injury and the effect is at least partially depend on the adjustment of TLR4-Myd88-NF-κB pathway and AQP1/AQP5 expression to reduce inflammatory reaction and lessen pulmonary edema. | QI Ying Chun CHEN Wen LI Xiao Ling WANG Yu Wei XIE Xiao Hua | 2014 | Biomedical and Environmental Sciences2014，27，6： | 17 |
| 5 | Simultaneous mineralization of CO_2 and recovery of soluble potassium using earth-abundant potassium feldspar显示文摘CO2 capture and storage(CCS) is an important strategy in combatting anthropogenic climate change.However,commercial application of the CCS technique is currently hampered by its high energy expenditure and costs.To overcome this issue,CO2 capture and utilization(CCU) is a promising CO2 disposal method.We,for the first time,developed a promising method to mineralize CO2 using earth-abundant potassium feldspar in order to effectively reduce CO2 emissions.Our experiments demonstrate that,after adding calcium chloride hexahydrate as an additive,the K-feldspar can be transformed to Ca-silicates at 800 C,which can easily mineralize CO2 to form stable calcium carbonate and recover soluble potassium.The conversion of this process reached 84.7%.With further study,the pretreatment temperature can be reduced to 250 C using hydrothermal method by adding the solution of triethanolamine(TEA).The highest conversion can be reached 40.1%.The process of simultaneous mineralization of CO2 and recovery of soluble potassium can be easily implemented in practice and may provide an economically feasible way to tackle global anthropogenic climate change. | XIE HePing WANG YuFei JU Yang LIANG Bin ZHU JiaHua ZHANG Ru XIE LingZhi LIU Tao ZHOU XiangGe ZENG HongMei LI Chun LU HouFang | 2013 | Chinese Science Bulletin2013，58，1： | 16 |
| 6 | Indirect mineral carbonation of titanium-bearing blast furnace slag coupled with recovery of TiO_2 and Al_2O_3显示文摘Large quantities of CO_2 and blast furnace slag are discharged in the iron and steel industry. Mineral carbonation of blast furnace slag can offer substantial CO_2 emission reduction and comprehensive utilization of the solid waste.This paper describes a novel route for indirect mineral carbonation of titanium-bearing blast furnace(TBBF) slag,in which the TBBF slag is roasted with recyclable(NH_4)_2SO_4(AS) at low temperatures and converted into the sulphates of various valuable metals, including calcium, magnesium, aluminium and titanium. High value added Ti-and Al-rich products can be obtained through stepwise precipitation of the leaching solution from the roasted slag. The NH_3 produced during the roasting is used to capture CO_2 from flue gases. The NH_4HCO_3 and(NH_4)_2CO_3 thus obtained are used to carbonate the CaSO_4-containing leaching residue and MgSO_4-rich leaching solution, respectively. In this study, the process parameters and efficiency for the roasting, carbonation and Ti and Al recovery were investigated in detail. The results showed that the sulfation ratios of calcium,magnesium, titanium and aluminium reached 92.6%, 87% and 84.4%, respectively, after roasting at an AS-to-TBBF slag mass ratio of 2:1 and 350 °C for 2 h. The leaching solution was subjected to hydrolysis at 102 °C for 4 h with a Ti hydrolysis ratio of 95.7% and the purity of TiO_2 in the calcined hydrolysate reached 98 wt%.99.7% of aluminium in the Ti-depleted leaching solution was precipitated by using NH_3. The carbonation products of Ca and Mg were CaCO_3 and(NH_4)_2 Mg(CO_3)_2·4H_2O, respectively. The latter can be decomposed into MgCO_3 at 100–200 °C with simultaneous recovery of the NH_3 for reuse. In this process, approximately 82.1% of Ca and 84.2%of Mg in the TBBF slag were transformed into stable carbonates and the total CO_2 sequestration capacity per ton of TBBF slag reached up to 239.7 kg. The TiO_2 obtained can be used directly as an end product, while the Al-rich precipitate and the two carbonation products can act, respectively, as raw materials for electrolytic aluminium,cement and light magnesium carbonate production for the replacement of natural resources. | Lin Wang Weizao Liu Jingpeng Hu Qiang Liu Hairong Yue Bin Liang Guoquan Zhang Dongmei Luo Heping Xie Chun Li | 2018 | Chinese Journal of Chemical Engineering2018，26，3： | 14 |
| 7 | Scientific and Engineering Progress in CO_2 Minerali zation Using Industrial Waste and Natural Minerals显示文摘The issues of reducing CO_2 levels in the atmo-sphere, sustainably utilizing natural mineral resources,and dealing with indus trial waste offer challenging opportunities for sustainable development in energy and the environment. The latest advances in CO_2 mineralization technology involving natural minerals and industrial waste are summarized in this paper, with great emphasis on the advancement of fundamental science, economic evaluation, and engineering applications. We discuss several lead-ing large-scale CO_2 mineralization methodologies from a techn ical and engineering-science perspective. For each technology option, we give an overview of the technical parameters, reaction pathway, reactivity, procedural scheme, and laboratorial and pilot devices. Furthermore, we present a discussion of each technology based on experimental results and the literature. Finally, current gaps in knowledge are identified in the conclusion, and an overview of the challenges and opportunities for future research in this field is provided. | Heping Xie Hairong Yue Jiahua Zhu Bin Liang Chun Li Yufei Wang Lingzhi Xie Xiangge Zhou | 2015 | Engineering2015，1，1： | 12 |
| 8 | An efficient methodology for utilization of K-feldspar and phosphogypsum with reduced energy consumption and CO2 emissions显示文摘The issues of reducing CO_2 emissions, sustainably utilizing natural mineral resources, and dealing with industrial waste offer challenges for sustainable development in energy and the environment. We propose an efficient methodology via the co-reaction of K-feldspar and phosphogypsum for the extraction of soluble potassium salts and recovery of SO_2 with reduced CO_2 emission and energy consumption. The results of characterization and reactivity evaluation indicated that the partial melting of K-feldspar and phosphogypsum in the hightemperature co-reaction significantly facilitated the reduction of phosphogypsum to SO_2 and the exchange of K^+(K-feldspar) with Ca^(2+)(CaSO_4 in phosphogypsum). The reaction parameters were systematically investigated with the highest sulfur recovery ratio of ~ 60% and K extraction ratio of ~ 87.7%. This novel methodology possesses an energy consumption reduction of ~ 28% and CO_2 emission reduction of ~ 55% comparing with the present typical commercial technologies for utilization of K-feldspar and the treatment of phosphogypsum. | Zhixi Gan Zheng Cui Hairong Yue Siyang Tang Changjun Liu Chun Li Bin Liang Heping Xie | 2016 | Chinese Journal of Chemical Engineering2016，24，11： | 11 |
| 9 | Clinical Characteristics of Children with Coronavirus Disease 2019 in Hubei, China显示文摘Since December 2019,COVID-19 has occurred unexpectedly and emerged as a health problem worldw ide.Despite the rapidly increasing number of cases in subsequent weeks,the clinical characteristics of pediatric cases are rarely described.A cross-sectional multicenter study was carried out in 10 hospitals across Hubei province.A total of 25 confirmed pediatric cases of COVID-19 were collected.The demographic data,epidemiological history,underlying discascs,clinical mani festations,laboratory and radiological data,treatments,and outcomes were analyzcd.Of 25 hospitalized patients with COVID-19,the boy to girl ratio was 1.27:1.The median age was 3 years.COVID-19 cases in children aged<3 years,3-6 years,and≥6-years patients were 10(40%),6(24%),and 9(36%),respectively.The most common symptoms at onset of ilness were fever(13[52%]),and dry cough(11[44%]).Chest CT images showed essential normal in 8 cases(33.3%),unilateral involvement of lungs in 5 cases(20.8%),and bilateral involvement in 11 cases(45.8%).Clinical diagnoses included upper respiratory tract infection(n=8),mild pneumonia(n=15),and critical cases(n=2).Two critical cases(8%)were given invasive mechanical ventilation,corticosteroids,and immunoglobulin.The symptoms in 24(96%)of 25 patients were alleviated and one patient had been discharged.It was concluded that children were susceptible to COVID-19 like adults,while the clinical presentations and outcomes were more favorable in children.However,children less than 3 years old accounted for majority cases and critical cases lied in this age group,which demanded extra attentions during home caring and hospitalization treatment. | Fang ZHENG Chun LIAO Qi-hong FAN Hong-bo CHEN Xue-gong ZHAO Zhong-guo XIE Xi-lin LI Chun-xi CHEN Xiao-xia LU Zhi-sheng LIU Wei LU Chun-bao CHEN Rong JIAO Ai-ming ZHANG Jin-tang WANG Xi-wei DING Yao-guang ZENG Li-ping CHENG Qing-feng HUANG Jiang WU Xi-chang LUO Zhu-jun WANG Yan-yan ZHONG Yan BAI Xiao-yan WU Run-ming JIN | 2020 | Current Medical Science2020，40，2： | 10 |
| 10 | Abnormal Audit Fees and Audit Opinion–Further Evidence from China's Capital Market显示文摘The existing literature on audit opinion shopping provides inconsistent evidence on whether such shopping has any association with abnormal audit fees. In this paper, we hypothesize that firms engage in audit opinion shopping and pay an abnormal audit fee only when their degree of accounting quality is low. To examine the issue, we group firms on the basis of their change in return on assets(ROA), and show that abnormal audit fees improve audit opinions only among firms that engage local auditors and have a low degree of ROA, but report a large increase in ROA, especially when the ROA change is the result of abnormal accruals. We find no association between abnormal audit fees and audit opinion improvement for other firms. | Zanchun Xie Chun Cai Jianming Ye | 2010 | China Journal of Accounting Research2010，，Z1： | 9 |
| 11 | Malnutrition and Quality of Life in Chinese Cancer Patients: a Clinical Study of 23,994 Subjects显示文摘Background Malnutrition is common in patients with cancer,and can negatively impact their quality of life(QoL)and even survival.However,there is currently no large data available on the prevalence of malnutrition in Chinese cancer patients.This study evaluated the prevalence of malnutrition and the QoL of Chinese patients with locoregional,recurrent or metastatic cancer.Methods We conducted a nationwide observational,multi-center,hospital-based cross-sectional study within the Chinese Society of Nutritional Oncology(CSNO)Network.All of the patients were diagnosed with one of the following 18 different types of malignant tumors:lung cancer,gastric cancer,liver cancer,colorectal cancer,breast cancer,esophageal cancer,cervical cancer,endometrial cancer,nasopharyngeal carcinoma,malignant lymphoma,leukemia,pancreatic cancer,ovarian cancer,prostate cancer,bladder cancer,brain cancer,biliary tract malignant tumors or gastrointestinal stromal tumors.These patients were enrolled from 72 hospitals located in different regions of China.The patients’nutritional status was evaluated based on the body mass index(BMI),loss of bodyweight,laboratory measurements and patient generated-subjective global assessment(PG-SGA)scores.The cancer patients’physical status and QoL were assessed by the Karnofsky Performance Status(KPS)questionnaire and the European Organization for Research and Treatment of Cancer(EORTC)QLQ-C30 questionnaire,respectively.Results From December 2013 to April 2016,23,994 patients hospitalized for cancer treatment(such as surgery,chemotherapy or radiotherapy)were enrolled in the study.The patients included 12,494(52.9%)males and 11,124(47.1%)females.The mean age was 55.8±13.7 years.The proportions of patients in cancer stagesⅠ,Ⅱ,Ⅲ,Ⅳand uncertain were 11.5%,20.3%,27.5%,30.2%and 10.5%,respectively.Among the 23,994 inpatients,the proportions of patients who were underweight(BMI<18.5 kg/m2),normal(18.5 kg/m2 | Hong Xia Xu Chun Hua Song Zhen Ming Fu Chang Wang Zeng Qing Guo Yuan Lin Ying Ying Shi Wen Hu Yi Ba Su Yi Li Zeng Ning Li Kun Hua Wang Jing Wu Ying He Jia Jun Yang Cong Hua Xie Fu Xiang Zhou Xin Xia Song Gong Yan Chen Wen Jun Ma Su Xia Luo Zi Hua Chen Ming Hua Cong Hu Ma Chun Ling Zhou Wei Wang Qi Luo Yong Mei Shi Yu Mei Qi Hai Ping Jiang Wen Xian Guan Jun Qiang Chen Jia Xin Chen Yu Fang Lan Zhou Yong Dong Feng Rong Shao Tan Tao Li Jun Wen Ou Qing Chuan Zhao Jian Xiong Wu Min Weng Qing Hua Yao Jiu Wei Cui Wei Li Han Ping Shi the Investigation on Nutrition Status and Clinical Outcome of Common Cancers(INSCOC)Group | 2021 | Journal of Nutritional Oncology2021，6，1： | 8 |
| 12 | Association of Overlapped and Un-overlapped Comorbidities with COVID-19 Severity and Treatment Outcomes: A Retrospective Cohort Study from Nine Provinces in China显示文摘Objective Several COVID-19 patients have overlapping comorbidities. The independent role of each component contributing to the risk of COVID-19 is unknown, and how some non-cardiometabolic comorbidities affect the risk of COVID-19 remains unclear.Methods A retrospective follow-up design was adopted. A total of 1,160 laboratory-confirmed patients were enrolled from nine provinces in China. Data on comorbidities were obtained from the patients’ medical records. Multivariable logistic regression models were used to estimate the odds ratio(OR) and 95% confidence interval(95% CI) of the associations between comorbidities(cardiometabolic or non-cardiometabolic diseases), clinical severity, and treatment outcomes of COVID-19.Results Overall, 158(13.6%) patients were diagnosed with severe illness and 32(2.7%) had unfavorable outcomes. Hypertension(2.87, 1.30–6.32), type 2 diabetes(T2 DM)(3.57, 2.32–5.49),cardiovascular disease(CVD)(3.78, 1.81–7.89), fatty liver disease(7.53, 1.96–28.96), hyperlipidemia(2.15, 1.26–3.67), other lung diseases(6.00, 3.01–11.96), and electrolyte imbalance(10.40, 3.00–26.10)were independently linked to increased odds of being severely ill. T2 DM(6.07, 2.89–12.75), CVD(8.47,6.03–11.89), and electrolyte imbalance(19.44, 11.47–32.96) were also strong predictors of unfavorable outcomes. Women with comorbidities were more likely to have severe disease on admission(5.46,3.25–9.19), while men with comorbidities were more likely to have unfavorable treatment outcomes(6.58, 1.46–29.64) within two weeks.Conclusion Besides hypertension, diabetes, and CVD, fatty liver disease, hyperlipidemia, other lung diseases, and electrolyte imbalance were independent risk factors for COVID-19 severity and poor treatment outcome. Women with comorbidities were more likely to have severe disease, while men with comorbidities were more likely to have unfavorable treatment outcomes. | MA Yan ZHU Dong Shan CHEN Ren Bo SHI Nan Nan LIU Si Hong FAN Yi Pin WU Gui Hui YANG Pu Ye BAI Jiang Feng CHEN Hong CHEN Li Ying FENG Qiao GUO Tuan Mao HOU Yong HU Gui Fen HU Xiao Mei HU Yun Hong HUANG Jin HUANG Qiu Hua HUANG Shao Zhen JI Liang JIN Hai Hao LEI Xiao LI Chun Yan LI Min Qing LI Qun Tang LI Xian Yong LIU Hong De LIU Jin Ping LIU Zhang MA Yu Ting MAO Ya MO Liu Fen NA Hui WANG Jing Wei SONG Fang Li SUN Sheng WANG Dong Ting WANG Ming Xuan WANG Xiao Yan WANG Yin Zhen WANG Yu Dong WU Wei WU Lan Ping XIAO Yan Hua XIE Hai Jun XU Hong Ming XU Shou Fang XUE Rui Xia YANG Chun YANG Kai Jun YUAN Sheng Li ZHANG Gong Qi ZHANG Jin Bo ZHANG Lin Song ZHAO Shu Sen ZHAO Wan Ying ZHENG Kai ZHOU Ying Chun ZHU Jun Teng ZHU Tian Qing ZHANG Hua Min WANG Yan Ping WANG Yong Yan 无 | 2020 | Biomedical and Environmental Sciences2020，33，12： | 8 |
| 13 | The prevalence of transfusion transmitted virus infection in blood donors显示文摘INIRODUCIIONA newly discovered DNA virus,transfusiontransmitted virus (TTV),was reported as a cause ofpost-transfusion hepatitis of unknown etiology inJapan.In order to investigate TTV prevalence insouthern China,a study was carried out amongblood donors,patients with liver diseases andhemodialysis to determine the epidemiologicalcharateristics. | Cheng Hui Huang Yu Sen Zhou Ru Guang Chen Chun Ying Xie Hai Tao Wang | 2000 | World Journal of Gastroenterology2000，6，2： | 7 |
| 14 | Validity of the Chinese Version of the Patient-Generated Subjective Global Assessment (PG-SGA) in Lung Cancer Patients显示文摘The prevalence of malnutrition is high among oncology patients in China. Although the Patient- Generated Subjective Global Assessment (PG-SGA) is widely recognized as an important nutritional assessment tool, it has not been validated for Chinese cancer patients. The purpose of this study was to conduct an analysis of nutrition screening and assessment data to validate the Chinese version of the PG-SGA in Chinese patients with lung cancer. This was an observational, cross-sectional study of 2,000 consecutive adult patients with lung cancer treated at several tertiary hospitals in China. Anthropometric and patient descriptive data were collected. The PG-SGA generated a score for the nutritional risk and a global rating for the nutritional status. The internal consistency, external consistency, and construct validity were evaluated, and a known-groups comparison and principal component analyses were conducted to evaluate the reliability and validity of the PG-SGA. The known-groups comparison demonstrated the ability of the PG-SGA to differentiate lung cancer patients of different nutritional and body mass index (BMI) groups. A confirmatory factor analysis supported the original four-factor structure of the PG-SGA. In terms of the internal and external consistency, the PG-SGA demonstrated intra-class correlation coefficients (ICC) up to 0.987. Alternative form validity was also demonstrated between Box 4 of the PG-SGA and the Karnofsky Performance Status score, with excellent external consistency (r = 0.972, P < 0.001). The construct validity was supported, and selected questionnaire dimensions were evident in the principal component analysis. Significant Spearman correlations (P < 0.001) were demonstrated. The Chinese version of the PG-SGA demonstrated significant reliability and sufficient exploratory properties to support its validity. It seems to be a valid tool that can be used to access the nutritional status of Chinese lung cancer patients. The validity of the PG-SGA in Chinese cancer patients warrants further investigation in other cancer types. | Zhen Ming Fu Hong Xia Xu Chun Hua Song Wei Li Zeng Qing Guo Yuan Lin Ying Ying Shi Wen Hu Yi Ba Su Yi Li Zeng Ning Li Kun Hua Wang Jing Wu Ying He Jia Jun Yang Cong Hua Xie Xin Xia Song Gong Yan Chen Wen Jun Ma Su Xia Luo Zi Hua Chen Ming Hua Cong Hu Ma Chun Ling Zhou Wei Wang Qi Luo Yong Mei Shi Yu Mei Qi Hai Ping Jiang Wen Xian Guan Jun Qiang Chen Jia Xin Chen Yu Fang Lan Zhou Yong Dong Feng Rong Shao Tan Tao Li Jun Wen Ou Qing Chuan Zhao Jian Xiong Wu Chang Wang Han Ping Shi The Investigation on Nutrition Status and Clinical Outcome of Common Cancers (INSCOC) Group | 2016 | Journal of Nutritional Oncology2016，1，1： | 7 |
| 15 | Effects of Propofol on Respiratory Drive and Patient-ventilator Synchrony during Pressure Support Ventilation in Postoperative Patients: A Prospective Study显示文摘 | Ling Liu Ai-Ping Wu Yi Yang Song-Qiao Liu Ying-Zi Huang Jian-Feng Xie Chun Pan Cong-Shan Yang Hai-Bo Qiu | 2017 | Chinese Medical Journal2017，，10： | 7 |
| 16 | Effects of high-frequency oscillatory ventilation and conventional mechanical ventilation on oxygen metabolism and tissue perfusion in sheep models of acute respiratory distress syndrome显示文摘 | Liu Songqiao Huang Yingzi Wang Maohua Chen Qiuhua Liu Ling Xie Jianfeng Tan Li Guo Fengmei Yang Congshan Pan Chun Yang Yi Qiu Haibo | 2014 | Chinese Medical Journal2014，，18： | 6 |
| 17 | FED:a web tool for foreign element detection of genome-edited organism显示文摘Dear Editor,Genome editing,especially the newly developed CRISPR technology,is now widely implemented for diverse medical and agricultural applications(Puchta,2018).However,for genome editing,the DNA cassettes encoding the editing components are usually assembled and delivered into the cells of organisms(Cong et al.,2013). | Qing Liu Xiaozhen Jiao Xiangbing Meng Chun Wang Cao Xu Zhixi Tian Chuanxiao Xie Genying Li Jiayang Li Hong Yu Kejian Wang | 2021 | Science China(Life Sciences)2021，64，1： | 6 |
| 18 | Validity of the Chinese Version of the Patient-Generated Subjective Global Assessment (PG-SGA) in Gastric Cancer Patients显示文摘Purpose Malnutrition is severe among gastric cancer patients in China. While the Patient-Generated Subjective Global Assessment (PG-SGA) is a widely used nutritional assessment tool, the validation for Chinese patients with gastric cancer has not been performed yet. The aim of this research is to validate the Chinese version of the PGSGA in Chinese gastric cancer patients by conducting analyses of nutrition screening and assessment data. Methods Two thousand consecutive adult patients with gastric cancer were included in this observational, cross-sectional study in several tertiary hospitals in China. A survey was made among those patients, which included several questionnaires and some anthropometric parameters. We calculated the parameters to validate the use of PG-SGA categorizing the nutritional status of gastric cancer patients. Then we performed statistical analysis to evaluate the internal consistency, external consistency, and construct validity. Results This study verified the ability of the PG-SGA to differentiate gastric cancer patients into different nutritional groups. The confirmatory factor analysis verified the original four-factor structure of the PG-SGA. The internal and external consistency was measured by a concordance analysis which showed an intraclass correlation coefficients (ICC) of 0.987. The correlations of the Box 4 score with the Karnofsky performance status score demonstrated alternative form validity with good external consistency (Pearson, r = 0.643, P < 0.001). All three anthropometric dimensions of the PG-SGA were supported by principal component analysis. Spearman correlations (P < 0.001) were significant in the majority of tests. Conclusion The Chinese version of the PG-SGA is a valid tool to access the patients’ nutritional status for Chinese gastric patients. | Zhen Ming Fu Hong Xia Xu Chun Hua Song Wei Li Zeng Qing Guo Yuan Lin Ying Ying Shi Wen Hu Yi Ba Su Yi Li Zeng Ning Li Kun Hua Wang Jing Wu Ying He Jia Jun Yang Cong Hua Xie Xin Xia Song Gong Yan Chen Wen Jun Ma Su Xia Luo Zi Hua Chen Ming Hua Cong Hu Ma Chun Ling Zhou Wei Wang Qi Luo Yong Mei Shi Yu Mei Qi Hai Ping Jiang Wen Xian Guan Jun Qiang Chen Jia Xin Chen Yu Fang Lan Zhou Yong Dong Feng Rong Shao Tan Tao Li Jun Wen Ou Qing Chuan Zhao Jian Xiong Wu Chang Wang Han Ping Shi The Investigation on Nutrition Status and Clinical Outcome of Common Cancers (INSCOC) Group | 2018 | Journal of Nutritional Oncology2018，3，4： | 5 |
| 19 | Serum osmolality and ions,and gill Na^(+)/K^(+)-ATPase of spottedtail goby Synechogobius ommaturus(R.)in response to acute salinity changes显示文摘This study was carried out to determine the effects of abrupt salinity change on osmoregulatory ability of the spottedtail goby Synechogobius ommaturus.720 juvenile fish(65.3±11.8 g)were transferred to 200 L tanks(with 40 juveniles in each tank),in which salinities were abruptly changed from 10 to 20,30,40,50 and freshwater.Survival rate,serum osmolality,electrolytes(Na^(+),Cl^(-),and K^(+))and gill Na^(+)/K^(+)-ATPase(NKA)activity were assessed successively in 528 h.Results showed serum osmolality,ion concentrations and gill Na^(+)/K^(+)-ATPase activity increased significantly when fish were transferred to salinity 40 and 50 and all fish in these groups died by the end of the experiment.Serum osmolality,Na^(+),Cl^(-)and K^(+)in fish transferred to a salinity of 20,30 and freshwater were not affected and no mortality was detected.Compared with the control group,a significantly decrease of NKA activity happened in the freshwater group,but the activity in 20 and 30 groups was not affected significantly.The results indicated that S.ommaturus could adapt rapidly and maintain homeostasis in a wide range of salinities(from freshwater to salinity 30)and this species may be suitable for aquaculture in estuarine and coastal areas where rapid salinity fluctuations commonly occur. | Chun Shui Yonghai Shi Xueming Hua Zhonghua Zhang Haiming Zhang Genhai Lu Yongde Xie | 2018 | Aquaculture and Fisheries2018，3，2： | 4 |
| 20 | Calculation method of quantum efficiency to TiO_2 nanocrystal photocatalysis reaction显示文摘The quantum yield is an important factor to evaluate the efficiency of photoreactor. This article gives an overall calculation method of the quantum efficiency( Φ ) and the apparent quantum efficiency( Φ a) to the TiO 2/UV photocatalysis system. Furthermore, for the immobility system (IS), the formulation of the faction of light absorbed by the TiO 2 thin film is proposed so as to calculate the quantum efficiency by using the measured value and theoretic calculated value of transmissivity (T). For the suspension system(SS), due to the difficulty to obtain the absorption coefficient ( α ) of TiO 2 particulates, the quantum efficiency is calculated by means of the relative photonic efficiency ( ζ r) and the standard quantum yield ( Φ standard ). | XIE Yi bing, YUAN Chun wei (National Laboratory of Molecular & Biomolecular Electronics, Southeast University, Nanjing 210096, China.) | 2002 | Journal of Environmental Sciences2002，14，1： | 4 |
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