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| 1 | Eleven COVID-19 Outbreaks with Local Transmissions Caused by the Imported SARS-CoV-2 Delta VOC-China,July-August,2021显示文摘Starting from December 2019,Wuhan,China,encountered the first outbreak of coronavirus disease 2019(COVID-19)(1-2).The epidemic was successfully suppressed by strict containment so that the number of infected people was reduced to 0 on April 8,2020(3–4).After that,China experienced roughly 3 dozen outbreaks with local transmission caused by imported severe acute respiratory syndrome coronavirus 2(SARS-CoV-2). | Lei Zhou Kai Nie Hongting Zhao Xiang Zhao Bixiong Ye Ji Wang Cao Chen Hong Wang Jiangli Di Jinsong Li Chao Li Zhixiao Chen Ruiqi Ren Peihua Niu Hui Chen Tao Chen Yali Wang Lili Li Bingxue Han Ruhan A Si Chen Dan Li Dan Li Chunxia Jin Xin Zhang Jiangmei Liu Chunyu Xu Yecheng Yao Yenan Feng Zhili Li Bike Zhang Yang Song Peter Hao Yanping Zhang Hao Li Qun Li George F.Gao Guoqing Shi Wenbo Xu | 2021 | China CDC weekly2021，3，41： | 13 |
| 2 | Effects of Shrub on Runoff and Soil Loss at Loess Slopes Under Simulated Rainfall显示文摘Improved understanding of the effect of shrub cover on soil erosion process will provide valuable information for soil and water conservation programs.Laboratory rainfall simulations were conducted to determine the effects of shrubs on runoff and soil erosion and to ascertain the relationship between the rate of soil loss and the runoff hydrodynamic characteristics.In these simulations a 20° slope was subjected to rainfall intensities of 45,87,and 127 mm/h.The average runoff rates ranged from 0.51 to 1.26 mm/min for bare soil plots and 0.15 to 0.96 mm/min for shrub plots.Average soil loss rates varied from 44.19 to 114.61 g/(min·m^2) for bare soil plots and from 5.61 to 84.58 g/(min·m^2) for shrub plots.There was a positive correlation between runoff and soil loss for the bare soil plots,and soil loss increased with increased runoff for shrub plots only when rainfall intensity is 127 mm/h.Runoff and soil erosion processes were strongly influenced by soil surface conditions because of the formation of erosion pits and rills.The unit stream power was the optimal hydrodynamic parameter to characterize the soil erosion mechanisms.The soil loss rate increased linearly with the unit stream power on both shrub and bare soil plots.Critical unit stream power values were 0.004 m/s for bare soil plots and 0.017 m/s for shrub plots. | XIAO Peiqing YAO Wenyi SHEN Zhenzhou YANG Chunxia LYU Xizhi JIAO Peng | 2017 | Chinese Geographical Science2017，27，4： | 5 |
| 3 | Double lock of a potent human therapeutic monoclonal antibody against SARS-CoV-2显示文摘Receptor recognition and subsequent membrane fusion are essential for the establishment of successful infection by SARS-CoV-2.Halting these steps can cure COVID-19.Here we have identified and characterized a potent human monoclonal antibody,HB27,that blocks SARS-CoV-2 attachment to its cellular receptor at sub-nM concentrations.Remarkably,HB27 can also prevent SARS-CoV-2 membrane fusion.Consequently,a single dose of HB27 conferred effective protection against SARS-CoV-2 in two established mouse models.Rhesus macaques showed no obvious adverse events when administrated with10 times the effective dose of HB27.Cryo-EM studies on complex of SARS-CoV-2 trimeric S with HB27 Fab reveal that three Fab fragments work synergistically to occlude SARS-CoV-2 from binding to the ACE2 receptor.Binding of the antibody also restrains any further conformational changes of the receptor binding domain,possibly interfering with progression from the prefusion to the postfusion stage.These results suggest that HB27 is a promising candidate for immuno-therapies against COVID-19. | Ling Zhu Yong-Qiang Deng Rong-Rong Zhang Zhen Cui Chun-Yun Sun Chang-Fa Fan Xiaorui Xing Weijin Huang Qi Chen Na-Na Zhang Qing Ye Tian-Shu Cao Nan Wang Lei Wang Lei Cao Huiyu Wang Desheng Kong Juan Ma Chunxia Luo Yanjing Zhang Jianhui Nie Yao Sun Zhe Lv Neil Shaw Qianqian Li Xiao-Feng Li Junjie Hu Liangzhi Xie Zihe Rao Youchun Wang Xiangxi Wang Cheng-Feng Qin | 2021 | National Science Review2021，8，3： | 3 |
| 4 | Effects of Different Combinations of Red and Blue Light on Morphology and Photosynthetic Characteristic of Tomato Seedlings显示文摘Blue and red light are spectral wavelengths more effective for plants. The effects of different ratios of red and blue light( R/B = 2,R/B = 4,R/B = 8,R/B = 12) provided by LEDs on morphology and photosynthetic characteristics of tomato seedlings were studied. The results showed that plant height,stem diameter,fresh weight,dry weight,seedling index and G value increased with the increase of R/B ratio until 8. On the contrary,SPDA value decreased with the increase of R/B ratio. Photosynthetic characteristics were measured by CO_2 assimilation( Pn),stomatal conductance( gs) and intracellular CO_2 concentration( Ci). Pn and gs decreased with the increase of R/B ratio. Furthermore,similar trend was investigated in photochemical quenching( q P) and electron transport rate( ETR).Results of this study suggest that compared with white LED,appropriate combination of red and blue light can enhance plant growth and photosynthetic characteristics,and the optimal blue/red ratio for tomato growth was R/B = 8. | Hong WANG Chunxia YAO Ying WANG Weimin ZHU | 2018 | Agricultural Biotechnology2018，7，5： | 3 |
| 5 | Curvature-controlled band alignment transition in 1D van der Waals heterostructures显示文摘The effect of curvature on the band alignment of one-dimensional (1D) van der Waals (vdW) transition metal dichalcogenide(TMDC) heterostructures is studied by comprehensive first-principles calculations. We find that, as the diameter of a TMDCnanotube decreases, the combined effect of curvature-induced flexoelectricity and circumferential tensile strain causes a rapidlowering of the conduction band minimum, whereas the valence band maximum exhibits an initial lowering before rising. Asindividual TMDC nanotubes form coaxial heterostructures, the concerted effect of diameter-dependent band-edge levels andintertube coupling via flexovoltage can result in a transition of intertube band alignment from Type II to Type I in multipleheterostructural systems, including large-diameter MoSe_(2)@WS_(2), MoTe_(2)@MoSe_(2), and MoTe_(2)@WS_(2) heterostructures. These results laydown a foundation for the rational design of 1D vdW heterostructures. | Shu Zhao Chunxia Yang Ziye Zhu Xiaoping Yao Wenbin Li | 2023 | npj Computational Materials2023，，1： | 1 |
| 6 | Combined cell grafting and VPA administration facilitates neural repair through axonal regeneration and synaptogenesis in traumatic brain injury显示文摘Neuronal regeneration and functional recovery are severely compromised following traumatic brain injury(TBl).Treatment options,including cell transplantation and drug therapy,have been shown to benefit TBl,although the underlying mechanisms remain elusive.In this study,neural stem cells(NSCs)are transplanted into TBl-challenged mice,together with olfactory ensheathing cells(OECs)or followed by valproic acid(VPA)treatment.Both OEC grafting and VPA treatment facilitate the differentiation of NSCs into neurons(including endogenous and exogenous neurons)and significantly attenuate neurological functional defects in TBl mice.Combination of NSCs with OECs or VPA administration leads to overt improvement in axonal regeneration,synaptogenesis,and synaptic plasticity in the cerebral cortex in TBl-challenged mice,as shown by retrograde corticospinal tract tracing,electron microscopy,growth-associated protein 43(GAP43),and synaptophysin(SYN)analyses.However,these beneficial effects of VPA are reversed by local delivery of N-methyl-D-aspartate(NMDA)into tissues surrounding the injury epicenter in the cerebral cortex,accompanied by a pronounced drop in axons and synapses in the brain.Our findings reveal that increased axonal regeneration and synaptogenesis evoked by cell grafting and VPA fosters neural repair in a murine model of TBl.Moreover,VPA-induced neuroprotective roles are antagonized by exogenous NMDA administration and its concomitant decrease in the number of neurons of local brain,indicating that increased neurons induced by VPA treatment mediate axonal regeneration and synaptogenesis in mice after TBl operation.Collectively,this study provides new insights into NSC transplantation therapy for TBI. | Sujuan Liu Haili Tian Yanmei Niu Chunxia Yu Lingjian Xie Zhe Jin Wenyan Niu Jun Ren Li Fu Zhi Yao | 2022 | Acta Biochimica et Biophysica Sinica2022，54，9： | 1 |
| 7 | Bank owner- ship, privatization, and performance: Evidence from a transition country显示文摘 | Jiang Chunxia Yao Shujie Feng Genfu | 2013 | Journal of Banking and Finance2013，37，9： | 1 |
| 8 | Surface modification of PET films by atmospheric pressure plasma-induced acrylic acid inverse emulsion graft polymerization显示文摘 | Jie Sun Lan Yao Zhiqiang Gao Shujing Peng Chunxia Wang Yiping Qiu | 2010 | Surface & Coatings Technology2010，，24： | 1 |
| 9 | Predictions of Spatially Averaged Cadmium Contents in Rice Grains in the Fuyang Valley, P.R. China显示文摘 | Brus Dick J Li Zhibo Song Jing Koopmans Gerwin F Temminghoff Erwin J M Yin Xuebin Yao Chunxia Zhang Haibo Luo Yongming Japenga Jan | 2009 | Journal of Environmental Quality2009，，3： | 1 |
| 10 | Mercury contamination in vicinity of secondary copper smelters in Fu yang, Zhejiang Province, China; Levels and contamination in topsoiIs显示文摘 | Xuebin Yin Chunxia Yao Jing Song | 2009 | Environmental Pollution2009，157，： | 1 |
| 11 | A Programmable Hybrid DNA Nanogel for Enhanced Photodynamic Therapy of Hypoxic Glioma显示文摘Photodynamic therapy(PDT)is a promising cancer therapy due to the evident advantages of a rapid curative eff ect,minimal or non-invasiveness,and circumvention of drug resistance.However,the hydrophobicity of photosensitizers and the hypoxic tumor microenvironment in solid tumors reduce the therapeutic eff ect of PDT immensely.Herein,we construct a programmable hybrid mesoporous silica nanoparticle/DNA nanogel(H-DNA nanogel)for enhanced PDT.The H-DNA nanogel is constituted with a virus-like mesoporous silica nanoparticle(VMSN)as the core to provide an appropriate nano-interface and a self-assembly programmable DNA hydrogel layer based on rolling circle amplifi cation(RCA)as the shell.Two kinds of G-quadruplex structures inserted with a hemin and zinc phthalocyanine(ZnPc)photosensitizer are introduced into the H-DNA nanogel by base pairing.The two modules of G-quadruplex structure work as an oxygen supplement in the hypoxic tumor microenvironment and increase the yield of singlet oxygen,respectively.Our hybrid DNA nanogel system provides a modular platform for effi cient cancer PDT and has great potential in the broader biomedical fi eld. | Ye Yuan Huiting Zhao Yunhua Guo Jianpu Tang Chunxia Liu Linghui Li Chi Yao Dayong Yang | 2020 | Transactions of Tianjin University2020，26，6： | 1 |
| 12 | WTO challenges and efficiency of Chinese banks显示文摘 | Yao Shujie Jiang Chunxia Feng Genfu | 2007 | Applied Economics2007，39，5： | 1 |
| 13 | The effects of governance changes on bank efficiency in China:A sto- chastic distance function approach显示文摘 | Jiang Chunxia Yao Shujie Zhang Zongyi | 2009 | China Economic Review2009，20，4： | 1 |
| 14 | Reconstruction of 3D Skin Model and Its Application in Evaluation the Efficacy of Cosmetic Raw Materials and Active Intredients显示文摘Via the use of Mimedisc~? as a scaffold, the normal human dermal fibroblasts were first seeding into the scaffold to form a dermal equivalent after three weeks, and then seeding normal human epidermal keratinocytes on it, followed by immersion and air-liquid interphase culture stage, to finally form a 3 D sponge matrix skin model which has a very similar structure of normal human skin(NHS). The results of Masson staining, and immunohistochemistry(IHC), immunofluorescence(IF) staininccg show that this skin model has a very similar structure and key protein expression of NHS. Meanwhile, this model was used as a tool to investigate the effect of Himalaya cedar extract on Dermal-Epidermal Junction(DEJ) in vitro. Results show that the Himalayan cedar extract can significantly increase the thickness of the epidermis, thus increase the barrier capacity of the skin to resist external environment. Further, this Himalaya cedar extract can promote the expressions of Laminin 5 and Collagen VII of DEJ. The expressions of the Laminin 5 and Collagen VII increased 20% and 47% respectively.So the Himalaya cedar extract displays the potential to be applied in development of anti-aging cosmetics. | Song Xiaojie Zhou Chunxia Yao Qifeng Wu Yue | 2018 | China Detergent & Cosmetics2018，3，1： | 0 |
| 15 | Estimating the air exchange rates in naturally ventilated cattle houses using Bayesian-optimized GBDT显示文摘It is challenging to estimate the air exchange rate(AER)dynamically in naturally ventilated livestock buildings such as dairy houses due to the influence of complex and variable outdoor environmental factors,large opening ratios,and the confusion of inflow and outflow at openings.This makes it difficult to efficiently regulate the opening ratio to meet the ventilation requirements in naturally ventilated livestock buildings.In this study,the air exchange rates of naturally ventilated cattle houses(NVCHs)in different seasons and opening ratios were obtained through field measurements and computational fluid dynamics(CFD)simulations.A fast and efficient machine learning framework was proposed and examined to predict AER based on the gradient boosting decision tree(GBDT)combined with Bayesian optimization.Compared with commonly used machine learning models such as multilayer perceptrons(MLPs)and support vector machines(SVMs),the proposed GBDT model has higher prediction accuracy and can avoid falling easily into local optima.Compared with the existing mechanical model based on the Bernoulli equation,the proposed GBDT model showed a slightly higher prediction than the mechanistic model and was much easier to use in AER estimation when inputting easily collected environmental factors in practical applications.Using Bayesian optimization could dramatically reduce the computing time when determining the optimal hyperparameter for establishing the GBDT model,dramatically saving on computing resources.Based on the Bayesian optimized GBDT model,the desirable opening ratio of the side curtain can be determined for automatically regulating the AER of cattle houses in future applications. | Luyu Ding Lei E Yang Lyu Chunxia Yao Qifeng Li Shiwei Huang Weihong Ma Ligen Yu Ronghua Gao | 2023 | International Journal of Agricultural and Biological Engineering2023，16，1： | 0 |
| 16 | Accurate reconstruction algorithm for bilateral differential phase signals显示文摘Background The differential phase computed tomography(DP-CT)imaging is a kind of X-ray-phase-based CT methods,which is widely used in various X-ray imaging laboratories.At present,a collection of projections with the horizontal direc-tion(perpendicular to the sample rotation axis)DP information is often acquired in DP-CT.In an ideal experiment,if the background is zero,then we can accurately reconstruct the information of each direction of the sample with horizontal data only.Actually,background information will produce streaking artifacts to affect the resolution in directions other than the horizontal direction.Purpose To mitigate the streaking artifacts in the conventionally reconstructed DP-CT images.Method This study develops a novel analytical DP-CT reconstruction framework by jointly using the bilateral DP information obtained along two perpendicular directions.In addition,a new data acquisition scheme is also proposed to quickly acquire the bilateral DP signal without the need of changing the direction of refraction signal acquisition.Results Experimental results demonstrate that this new algorithm is able to greatly reduce the streaking artifacts on DP-CT images. | Qili He Yan Wang Panyun Li Chunxia Yao Jin Zhang Tianyu Fu Kai Zhang Qingxi Yuan Wanxia Huang Shanfeng Wang Peiping Zhu Peng Liu | 2021 | Radiation Detection Technology and Methods2021，5，3： | 0 |
| 17 | An investigation on arsenic contamination near small factories of metal smelter in Zhejiang Province显示文摘 | Chunxia YAO Xuebin YIN Yongming LUO Jing SONG De BI Feng XUE | 2006 | Chinese Journal Of Geochemistry2006，25，B08： | 0 |
| 18 | A preliminary study on interaction of Hg and Se in Sedum alfredii Hance显示文摘 | Xuebin YIN Chunxia YAO De BI Yongming LUO Jing SONG | 2006 | Chinese Journal Of Geochemistry2006，25，B08： | 0 |
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