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| 1 | Running-in Test and Fractal Methodology for Worn Surface Topography Characterization显示文摘Studying and understanding of the surface topography variation are the basis for analyzing tribological problems,and characterization of worn surface is necessary.Fractal geometry offers a more accurate description for surface roughness that topographic surfaces are statistically self-similar and can be quantitatively evaluated by fractal parameters.The change regularity of worn surface topography is one of the most important aspects of running-in study.However,the existing research normally adopts only one friction matching pair to explore the surface topography change,which interrupts the running-in wear process and makes the experimental result lack authenticity and objectivity.In this paper,to investigate the change regularity of surface topography during the real running-in process,a series of running-in tests by changing friction pairs under the same operating conditions are conducted on UMT-II Universal Multifunction Tester.The surface profile data are acquired by MiaoXAM2.5X-50X Ultrahigh Precision Surface 3D Profiler and analyzed using fractal dimension D,scale coefficient C and characteristic roughness Ra *based on root mean square(RMS) method.The characterization effects of the three parameters are discussed and compared.The results obtained show that there exists remarkable fractal feature of surface topography during running-in process,both D and Ra *increase gradually,while C decreases slowly as the wear-in process goes on,and all parameters tend to be stable when the wear process steps into the normal wear process.Ra *illustrates higher sensitivity for rough surface characterization compared with the other two parameters.In addition,the running-in test carried with a set of identical surface properties is more scientific and reasonable than the traditional one.The proposed research further indicates that the fractal method can quantitatively measure the rough surface,which also provides an evidence for running-in process identification and tribology design. | JI Cuicui ZHU Hua JIANG Wei LU Binbin | 2010 | Chinese Journal of Mechanical Engineering2010，23，5： | 18 |
| 2 | Targets and molecular mechanisms of triptolide in cancer therapy显示文摘Triptolide(TPL/TL) is a natural drug with novel anticancer effects. Preclinical studies indicated that TPL inhibits cell proliferation, induces cell apoptosis, inhibits tumor metastasis and enhances the effect of other therapeutic methods in various cancer cell lines. Multiple molecules and signaling pathways, such as caspases, heat-shock proteins, NF-κB, and deoxyribonucleic acid(DNA) repair-associated factors, are associated with the anti-cancer effect. TPL also improves chemoradiosensitivity in cancer therapy. Phase I trials indicate the potential clinical value of TPL use. However, further trials with larger sample sizes are needed to confirm these results. | Cuicui Meng Hongcheng Zhu Hongmei Song Zhongming Wang Guanhong Huang Defan Li Zhaoming Ma Jianhua Ma Qin Qin Xinchen Sun Jianxin Ma | 2014 | Chinese Journal of Cancer Research2014，26，5： | 16 |
| 3 | Fractal Prediction Model of Thermal Contact Conductance of Rough Surfaces显示文摘The thermal contact conductance problem is an important issue in studying the heat transfer of engineering surfaces,which has been widely studied since last few decades,and for predicting which many theoretical models have been established.However,the models which have been existed are lack of objectivity due to that they are mostly studied based on the statistical methodology characterization for rough surfaces and simple partition for the deformation formats of contact asperity.In this paper,a fractal prediction model is developed for the thermal contact conductance between two rough surfaces based on the rough surface being described by three-dimensional Weierstrass and Mandelbrot fractal function and assuming that there are three kinds of asperity deformation modes:elastic,elastoplastic and fully plastic.Influences of contact load and contact area as well as fractal parameters and material properties on the thermal contact conductance are investigated by using the presented model.The investigation results show that the thermal contact conductance increases with the increasing of the contact load and contact area.The larger the fractal dimension,or the smaller the fractal roughness,the larger the thermal contact conductance is.The thermal contact conductance increases with decreasing the ratio of Young's elastic modulus to the microhardness.The results obtained indicate that the proposed model can effectively predict the thermal contact conductance at the interface,which provide certain reference to the further study on the issue of heat transfer between contact surfaces. | JI Cuicui ZHU Hua JIANG Wei | 2013 | Chinese Journal of Mechanical Engineering2013，26，1： | 11 |
| 4 | A novel method to identify the scaling region for chaotic time series correlation dimension calculation显示文摘To obtain more accurate correlation dimension estimations for chaotic time series, a novel scaling region identification method is developed. First, points that obviously do not belong to the scaling region associated with the whole double logarithm correlation integral curve are removed using the K-means algorithm. Second, a point-slope-error algorithm is developed to recognize a possible scaling region. Third, the K-means algorithm is used again to further remove a small interval of interfering points in the possible scaling region to obtain a more precise scaling region. The correlation dimension of four typical chaotic attractors and five curves generated by the Weierstrass-Mandelbrot fractal function were calculated using the proposed method. These calculated values were very close to the respective theoretical fractal dimensions. Moreover, the effectiveness of our method in identifying the scaling region was compared with existing methods. Results show that our method can distinguish the scaling region objectively, accurately, automatically and quickly, making estimations of the correlation dimension more precise and affording significant improvements in nonlinear analysis. | JI CuiCui ZHU Hua JIANG Wei | 2011 | Chinese Science Bulletin2011，56，9： | 7 |
| 5 | Macrophage-derived small extracellular vesicles promote biomimetic mineralized collagen-mediated endogenous bone regeneration显示文摘Macrophages play an important role in material-related immune responses and bone formation,but the functionality of macrophage-derived extracellular vesicles(EVs)in material-mediated bone regeneration is still unclear.Here,we evaluated intracellular communication through small extracellular vesicles(sEVs)and its effects on endogenous bone regeneration mediated by biomimetic intrafibrillarly mineralized collagen(IMC).After implantation in the bone defect area,IMC generated more neobone and recruited more mesenchymal stem cells(MSCs)than did extrafibrillarly mineralized collagen(EMC).More CD63+CD90+and CD63+CD163+cells were detected in the defect area in the IMC group than in the EMC group.To determine the functional roles of sEVs,extracellular vesicles from macrophages cultured on different mineralized collagen were isolated,and they showed no morphological differences.However,macrophage-derived sEVs in the IMC group showed an enhanced Young’s modulus and exerted beneficial effects on the osteogenic differentiation of bone marrow MSCs by increasing the expression of the osteoblastic differentiation markers BMP2,BGLAP,COL1,and OSX and calcium nodule formation.Mechanistically,sEVs from IMC-treated macrophages facilitated MSC osteogenesis through the BMP2/Smad5 pathway,and blocking sEV secretion with GW4869 significantly impaired MSC proliferative,immunomodulative and osteogenic potential.Taken together,these findings show that macrophage-derived sEVs may serve as an emerging functional tool in biomaterial-mediated endogenous bone regeneration. | Anqi Liu Shanshan Jin Cuicui Fu Shengji Cui Ting Zhang Lisha Zhu Yu Wang Steve G.F.Shen Nan Jiang Yan Liu | 2020 | International Journal of Oral Science2020，12，4： | 5 |
| 6 | Three decades of changes in water environment of a large freshwater Lake and its relationship with socio-economic indicators显示文摘Tai Lake(Ch: Taihu) has attracted international attention forcyanobacteria blooms.However, the drivers of cultural eutrophication, especially long-term socio-economic indicators have been little researched. The results of research demonstrate how socioeconomic development affected quality of water and how it has been improved by anthropogenic activities. This study described variability in indicators of water quality in Tai Lakeand investigated thedrivers. Significant relationships existed between concentrations of annual mean total nitrogen(TN), total phosphorous(TP), chemical oxygen demand(COD) and biological oxygen demand(BOD), and population, per capital gross domestic production(GDP) and sewage discharge(p < 0.05). However, mechanisms causing change varied among TN, TP, COD and BOD. Before 2000, the main contributors to increases in concentrations of TN were human population, GDP and volumes of domestic sewage discharges. After 2000, discharges of industrial sewage become the primary contributor. After 1998, the regressions of annual mean TN, TP and COD on per capital GDP, population and domestic sewage discharge were reversed compared to the former period. Since 1999, an apparent inverted U-shaped relationship between environmental pollution and economic development has developed, which indicated that actions taken by governments have markedly improved quality of water in Tai Lake. The statistical relationship between BOD and per capital GDP didn't conform to the Kuznet curve. The Ushaped Kuznet curve may offer hope for the future that with significant environmental investments a high GDP can be reached and maintained without degradation of the environment, especially through appropriate management of industrial sewage discharge. | Cuicui Li Weiying Feng Fanhao Song Zhongqi He Fengchang Wu Yuanrong Zhu John P.Giesy Yingchen Bai | 2019 | Journal of Environmental Sciences2019，31，3： | 3 |
| 7 | An actively ultrafast tunable giant slow-light effect in ultrathin nonlinear metasurfaces显示文摘A slow-light effect based on metamaterial-induced transparency(MIT)possesses great practical applications for integrated photonic devices.However,to date,only very weak slow-light effects have been obtained in metamaterials because of the intrinsic loss of metal.Moreover,no active control of slow-light has been achieved in metamaterials.Here,we report the realization of a giant slow-light effect on an ultrathin metasurface that consists of periodic arrays of gold nanoprism dimers with a thickness of 40 nm sandwiched between a multilayer-graphene micro-sheet/zinc oxide nanoparticle layer and a monolayer graphene/polycrystalline indium tin oxide layer.The strong field confinement of the plasmonic modes associated with the MIT ensures a tremendous reduction in the group velocity around the transparency window.A group index of more than 4×10^(3) is achieved,which is one order of magnitude greater than that of previous reports.A large tunable wavelength range of 120 nm is achieved around the center of the transparency window when the pump light intensity is only 1.5 kW cm^(-2).The response time is as fast as 42.3 ps.These results demonstrate the potential for the realization of various functional integrated photonic devices based on metasurfaces,such as all-optical buffers and all-optical switches. | Cuicui Lu Xiaoyong Hu Kebin Shi Qin Hu Rui Zhu Hong Yang Qihuang Gong | 2015 | Light(Science & Applications)2015，4，1： | 3 |
| 8 | Polyploidy Induction of Pteroceltis tatarinowii Maxim.显示文摘[Objective] This study was conducted to obtain tetraploid Pteroceltis tatarinowii Maxim. with excellent ornamental traits. [Method] The stem apex growing points of Pteroceltis tatarinowii Maxim. were treated with different concentrations of colchicine solution for different hours to figure out a proper method and obtain polyploids. [Result] The most effective induction was obtained by treatment with 0.6%-0.8% colchicine for 72 h with 34.2% mutation rate. Flow cytometry and chromosome observation of the stem apex growing point of P. tatarinowii Maxim. proved that the tetraploid plants were successfully obtained with chromosome number 2n =4x =36.[Conclusion] The result not only fills the blank of polyploid breeding of P. tatarinowii,but also provides an effective way to broaden the methods of cultivation of fastgrowing, high-quality, disease-resilience, new varieties of Pteroceltis. | Lin ZHANG Feng WANG Zhongkui SUN Cuicui ZHU Rongwei CHEN | 2015 | Agricultural Science & Technology2015，16，6： | 2 |
| 9 | Development of multiplex loop-mediated isothermal amplification-RFLP (mLAMP-RFLP) to detect Salmonella spp. and Shigella spp. in milk显示文摘 | Yanchun Shao Shengmei Zhu Cuicui Jin Fusheng Chen | 2011 | International Journal of Food Microbiology2011，，2： | 1 |
| 10 | Finite-time control of discrete-time systems with time-varying exogenous disturb- anee显示文摘 | ZHU Lin SHEN Yanjun LI Cuicui | 2009 | Comraunieation in Nonlinear Science and Numerical Simulation2009，14，： | 1 |
| 11 | Finite-time control of discrete-time systems with time-varying exogenous disturbance显示文摘 | Lin Zhu Yanjun Shen Cuicui Li | 2009 | Communications in Nonlinear Science and Numerical Simulation2009，14，： | 1 |
| 12 | A non-ACE2 competing human single-domain antibody confers broad neutralization against SARS-CoV-2 and circulating variants显示文摘The current COVID-19 pandemic has heavily burdened the global public health system and may keep simmering for years.The frequent emergence of immune escape variants have spurred the search for prophylactic vaccines and therapeutic antibodies that confer broad protection against SARS-CoV-2 variants.Here we show that the bivalency of an affinity maturated fully human singledomain antibody(n3113.1-Fc)exhibits exquisite neutralizing potency against SARS-CoV-2 pseudovirus,and confers effective prophylactic and therapeutic protection against authentic SARS-CoV-2 in the host cell receptor angiotensin-converting enzyme 2(ACE2)humanized mice.The crystal structure of n3113 in complex with the receptor-binding domain(RBD)of SARS-CoV-2,combined with the cryo-EM structures of n3113 and spike ecto-domain,reveals that n3113 binds to the side surface of up-state RBD with no competition with ACE2.The binding of n3113 to this novel epitope stabilizes spike in up-state conformations but inhibits SARS-CoV-2 S mediated membrane fusion,expanding our recognition of neutralization by antibodies against SARS-CoV-2.Binding assay and pseudovirus neutralization assay show no evasion of recently prevalent SARS-CoV-2 lineages,including Alpha(B.1.1.7),Beta(B.1.351),Gamma(P.1),and Delta(B.1.617.2)for n3113.1-Fc with Y58L mutation,demonstrating the potential of n3113.1-Fc(Y58L)as a promising candidate for clinical development to treat COVID-19. | Zhenlin Yang Yulu Wang Yujia Jin Yuanfei Zhu Yanling Wu Cheng Li Yu Kong Wenping Song Xiaolong Tian Wuqiang Zhan Ailing Huang Shanshan Zhou Shuai Xia Xiaoxu Tian Chao Peng Cuicui Chen Yibing Shi Gaowei Hu Shujuan Du Yuyan Wang Youhua Xie Shibo Jiang Lu Lu Lei Sun Yuanlin Song Tianlei Ying | 2021 | Signal Transduction and Targeted Therapy2021，6，12： | 1 |
| 13 | Microstructure and high temperature wear of the aluminum matrix composites fabricated by reaction from Al–ZrO 2 –B elemental powders显示文摘 | Heguo Zhu Cuicui Jia Jianliang Li Jun Zhao Jinzhu Song Yinqun Yao Zonghan Xie | 2011 | Powder Technology2011，，： | 1 |
| 14 | Finite-time control of dis-crete-time systems with time-varying exogenous disturbance 显示文摘 | Zhu Lin Shen Yanjun Li Cuicui | 2009 | Communications in Nonlinear Science and Numerical Simulation2009，141，： | 1 |
| 15 | Remarkable improvement of cyclic stability in Li-O2 batteries using ruthenocene as a redox mediator显示文摘Nonaqueous Li-O2 batteries attract attention for their theoretical specific energy density.However,due to the difficulty of decomposition of Li2 O2,Li-O2 batteries have high charge overpotential and poor cycling life.So all kinds of catalysts have been studied on the cathode.Compared to heterogeneous solid catalysts,soluble catalysts achieve faster and more effective transport of electrons by reversible redox pairs.Here,we first report ruthenocene(Ruc) as a mobile redox mediator in a Li-O2 battery.0.01 mol/L Ruc in the electrolyte effectively reduces the charging voltage by 610 mV.Additionally,Ruc greatly increases the cycling life by four-fold(up to 83 cycles) with a simple ketjen black(KB) cathode.The results of SEM,XPS and XRD confirm that less discharge product residue accumulated after recharge.To verify the reaction mechanisms of the mediato r,free energy profiles of the possible reaction pathways based on DFT are provided. | Cuicui Zhu Yiping Wang Ling Shuai Yizhao Tang Ming Qiu Jian Xie Jia Liu Wen Wen Hengquan Chen Suifei Nan Mei Dou Qinggang He | 2020 | Chinese Chemical Letters2020，31，7： | 1 |
| 16 | Neuroprotection by selective neuronal deletion of Atg7 in neonatal brain injury显示文摘 | Cuicui Xie Vanessa Ginet Yanyan Sun Masato Koike Kai Zhou Tao Li Hongfu Li Qian Li Xiaoyang Wang Yasuo Uchiyama Anita C. Truttmann Guido Kroemer Julien Puyal Klas Blomgren Changlian Zhu | 2016 | Autophagy2016，，： | 1 |
| 17 | Correction to“Multifunctional Flexible Vanadium Dioxide Films”显示文摘The author affiliation of the author Ying Zhu should be changed to“State Key Laboratory of High-Performance Ceramics and Superfine Microstructure,Shanghai Institute of Ceramics,Chinese Academy of Sciences,Shanghai 200050,China”.Miss Zhu received her M.S.in Materials Engineering from Shanghai Institute of Ceramics,Chinese Academy of Sciences,in 2020.Then she became a joint Ph.D.student of The University of British Columbia,Canada and Southern University of Science and Technology,China. | Tianci Chang Ying Zhu Cuicui Cao Chunlei Yang Hongjie Luo Ping Jin Xun Cao | 2022 | Accounts of Materials Research2022，3，3： | 0 |
| 18 | Lateral organic-inorganic hybrid Vis-NIR photodetectors based on GaN nanowires promoting photogenerated carriers transfer显示文摘The narrow bandgap of the low-energy near-infrared(NIR)polymer would lead to overlap between adjacent energy levels,which is a major barrier to the preparation of Vis-NIR polymer bulk hetero-junction(BHJ)photodetectors with small responsivity and photocurrent.In this study,a high-performance lateral inorganic-organic hybrid photodetector was constructed to eliminate this barrier by combining GaN nanowires(GaN-NWs)with PDPP3T:PC61BM-based BHJ.In stage one,high-quality GaN-NWs were synthesized by the catalyst-free CVD method.The mechanism for controlling GaN-NWs morphology by adjusting the NH3 flow rate was revealed.In stage two,the GaN-NWs with large electron mobility were used to accelerate the transfer of photogenerated carriers in the BHJ layer.Finally,compared with the BHJ device,the BHJ/GaN device demonstrated obvious improvements in responsivity and photocurrent at the wavelength between 400 and 1000 nm.The responsivity and photocurrent increased over 20-fold at the NIR band of 800e900 nm.Besides,owing to the energy level gradient effect,the BHJ/GaN device has a response speed of 7.8/<5.0 ms,which increases over three orders of magnitude than that of the GaN-NWs-based device(tr/tf:7.1/10.9 s).Therefore,the novel device structure proposed in this work holds great potential for preparing high-performance Vis-NIR photodetectors. | Tao Han Zexin Wu Zhilong Deng Xiaofeng Zhang Sidi Yang Cuicui Chen Jiajia Zhu Shufang Ding Chunzhi Jiang | 2022 | Journal of Materiomics2022，8，4： | 0 |
| 19 | Effects of mixed fertilizers formed by the compounding of two targeted controlled-release nitrogen fertilizers on yield,nitrogen use efficiency,and ammonia volatilization in double-cropping rice显示文摘One-time application of mixed fertilizer formed by the compounding of two controlled-release nitrogen fertilizers(CRUs)with targeted N supply during the periods from transplantation(TS)to panicle initiation(PI)and from PI to heading(HS)is expected to synchronize the double-peak N demand of rice.However,its effects on the yield and N use efficiency(NUE)of labor-intensive double-cropping rice were unknown.Two targeted CRU(CRU_(A)and CRU_(B))were compounded in five ratios(CRU_(A):CRU_(B)=10:0,7:3,5:5,3:7,and 0:10)to form five mixed fertilizers(BBFs):BBF1-5.A field experiment was performed to investigate the characteristics of N supply in early and late seasons under different BBFs and their effects on N uptake,yield,and ammonia volatilization(AV)loss from paddy fields of double-cropping rice.Conventional high-yield fertilization(CK,three split applications of urea)and zero-N treatments were established as controls.The N supply dropped significantly with the increased compound ratio of CRU_(B)during the period from TS to PI,but increased during the period from PI to HS.With the exception of the period from TS to PI in the late rice season,the N uptake of early and late rice maintained close synchronicity with the N supply of BBFs during the double-peak periods.Excessive N supply(BBF1 and BBF2)in the late rice season during the period from TS to PI increased N loss by AV.The effect of BBF on grain yield increase varied widely between seasons,irrespective of year.Among the BBFs,the BBF2 treatment of early rice not only stabilized the spikelets per panicle but also ensured a high number of effective panicles by promoting N uptake during the period from TS to PI and a high grain-filling percentage by appropriately reducing the N supply at the later PI stage,resulting in the highest rice yield.While stabilizing the effective panicle number,the BBF4 treatment of late rice increased the number of spikelets per panicle by promoting N uptake during the period from PI to HS,resulting in the highest rice yield.The two-year average yield and apparent N recovery efficiency of the BBF2 treatment during the early rice season were 9.6 t ha 1 and 45.3%,while those of late rice in BBF4 were 9.6 t ha 1 and 43.0%,respectively.The yield and NUE indexes of BBF2 in early rice and BBF4 in late rice showed no significant difference from those of CK.The AVs of BBF2 during the early rice season and of BBF4 during the late rice season were 50.0%and 76.8%lower,respectively,than those of CK.BBF2 and BBF4 could effectively replace conventional urea split fertilization in early and late rice seasons,ensuring rice yield and NUE and reducing AV loss in paddy fields. | Jian Ke Jie Sun Tingting Chen Shibao Tao Tiezhong Zhu Chuanjun Yin Haibing He Cuicui You Liquan Wu Shuangshuang Guo | 2023 | The Crop Journal2023，11，2： | 0 |
| 20 | Multifunctional Flexible Vanadium Dioxide Films显示文摘CONSPECTUS:As a typical phase transition material,vanadium dioxide(VO_(2))has attracted much attention due to its amazing metal−insulator transition(MIT)at the critical temperature of 68°C,which could be driven by multiple stimuli,including electricity,thermal irradiation,THz waves,strain,etc.In the MIT process,VO_(2)exhibits significant changes in its structure from monoclinic structure at low temperature to rutile structure at high temperature,accompanied by significant modulation of physical properties,such as the infrared transmittance from high to low and a resistivity drop over 5 magnitudes.Based on these features,VO_(2)has functioned as thermochromic coatings,sensors,switches,electronic devices,actuators,etc.However,the vanadium element possesses multiple valent states and can produce complicated thermodynamics of vanadium oxides.The fabrication of tetravalence VO_(2)with desirable phase-transition features usually requires rigorous fabrication conditions with a precisely controlled atmosphere for stoichiometric components and high temperatures for good crystallinity.Under these circumstances,it is difficult to directly fabricate crystalline VO_(2)films on flexible polymer substrates because most of them could not stand such high temperatures(usually>400°C),which will lead to the loss of the substrate functionality.However,the featured phase transition of VO_(2)makes it a promising candidate for future flexible devices,while VO_(2)owns great potential as flexible optical coatings,flexible sensors,flexible electronics,etc.Hence,research on flexible VO_(2)films is necessary and could largely pave the way to the application field of VO_(2)material.In this Account,we start with a brief introduction to phase transition properties of VO_(2)to reveal the intrinsic advantages as key materials in flexible devices.Next,multifunctional devices based on flexible VO_(2)films with different forms and characteristics are presented,including(1)flexible VO_(2)-film-based thermochromic smart windows for energy-saving function depending on the change of environmental temperatures,(2)flexible VO_(2)films optical devices based on the changing emissivity of VO_(2),(3)flexible VO_(2)films with compatibility as multifunctional sensors,(4)next-generation flexible electronics based on VO_(2)films,and(5)flexible VO_(2)actuators with significant mechanical motions under external stimuli.Meanwhile,various fabrication technologies of flexible VO_(2)films have been introduced and discussed.Finally,we end the Account with an overview of the remaining challenges and new opportunities that have been opened up for vanadium dioxide in new forms of flexible optical and electronic devices.We hope this Account will inspire new innovative designs,fabrication approaches,and more possible functions of flexible VO_(2)films in future work. | Tianci Chang Ying Zhu Cuicui Cao Chunlei Yang Hongjie Luo Ping Jin Xun Cao | 2021 | Accounts of Materials Research2021，2，9： | 0 |
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