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| 1 | Neuroprotective effect of ethyl acetate extract from gastrodia elata against transient focal cerebral ischemia in rats induced by middle cerebral artery occlusion显示文摘OBJECTIVE: To investigate the protective effect of neuroprotection against transient focal cerebral ischemia of the extract from Tianma(Rhizoma Gastrodiae) and the possible mechanisms underlying the action.METHODS: Cerebral ischemia-reperfusion injury was induced through middle cerebral artery occlusion(MCAO). Adult male Sprague-Dawley rats were randomly divided into four groups: sham-operated,ischemia-reperfusion model, 102.6 mg/kg extract treated and 11.4 mg/kg extract treated groups. The extract was prepared from gastrodia elata with ethyl acetate. The effect of the extract tested on rat neurological de fi cits and Cerebral index, cerebral infarct volume, brain injury, terminal dexynucleotidyl transferase-mediated d UTP nick end labeling(TUNEL) and B-cell lymphoma-2(Bcl-2) positive cells.RESULTS: The extract was able to reduce neurological scores, cerebral index and cerebral infarction rate. The brain injury was also relieved by the extract. The results of immunofluorescence staining analysis indicated that the extract increased the expression of Bcl-2 and reduced TUNEL-positive cells significantly in the extract treated groups.CONCLUSION: These results suggested that the extract relieved ischemic injury induced by transient focal cerebral ischemia in rats, and this neuroprotective effect might be partially due to the attenuated apoptosis pathway. | Duan Xiaohua Wang Weili Liu Xiaoqing Yan Hanwen Dai Rong Lin Qing | 2015 | Journal of Traditional Chinese Medicine2015，35，6： | 18 |
| 2 | Shake table tests of suspended ceilings to simulate the observed damage in the M_s 7.0 Lushan earthquake, China显示文摘Severe damage to suspended ceilings of metal grids and lay-in panels was observed in public buildings during the 2013 Ms7.0 Lushan earthquake in China. Over the past several years, suspended ceilings have been widely used practice in public buildings throughout China, including government offices, schools and hospitals. To investigate the damage mechanism of suspended ceilings, a series of three-dimensional shake table tests was conducted to reproduce the observed damage. A full-scale reinforced concrete frame was constructed as the testing frame for the ceiling, which was single-story and infilled with brick masonry walls to represent the local construction of low-rise buildings. In general, the ceiling in the tests exhibited similar damage phenomena as the field observations, such as higher vulnerability of perimeter elements and extensive damage to the cross runners. However, it exhibited lower fragility in terms of peak ground/roof accelerations at the initiation of damage. Further investigations are needed to clarify the reasons for this behavior. | Wang Duozhi Dai Junwu Qu Zhe Ning Xiaoqing | 2016 | Earthquake Engineering and Engineering Vibration2016，15，2： | 13 |
| 3 | Experimental Study and Model Analysis of the Performance of IPMC Membranes with Various Thickness显示文摘 | Qingsong He Min Yu Linlin Song Haitao Ding Xiaoqing Zhang Zhendong Dai | 2011 | Journal of Bionic Engineering2011，8，1： | 10 |
| 4 | Ni-Co/Mg-Al catalyst derived from hydrotalcite-like compound prepared by plasma for dry reforming of methane显示文摘Ni-Co bimetallic catalysts with different Ni/Co content were derived from cold plasma jet decomposition and reduction of hydrotalcite-like compounds containing Ni,Co,Mg and Al,and their catalytic performance was investigated with dry reforming of methane.Experimental results showed that the hydrotalcite-like precursors could be completely decomposed and partly reduced by cold plasma jet,and the Nicontained catalysts exhibited much higher activity than the catalyst without Ni.Especially,the catalyst with Ni/Co ratio of 8/2 achieved not only the highest conversions of 80.3%and 69.3%for CH4 and CO2,respectively,but also the best stability in 100 h testing.The catalysts were characterized by XRD,XPS,TEM and N2 adsorption techniques,and the results showed that the better performance of the 8Ni2Co bimetallic catalyst was attributed to its higher metal dispersion,smaller metal particle size,as well as the interaction effect between Ni and Co,which were brought by the special catalyst preparation method. | Huali Long Yan Xu Xiaoqing Zhang Shijing Hu Shuyong Shang Yongxiang Yin Xiaoyan Dai | 2013 | Journal of Energy Chemistry2013，22，5： | 8 |
| 5 | Experimental and analytical studies on multiple tuned mass dampers for seismic protection of porcelain electrical equipment显示文摘Porcelain electrical equipment(PEE),such as current transformers,is critical to power supply systems,but its seismic performance during past earthquakes has not been satisfactory.This paper studies the seismic performance of two typical types of PEE and proposes a damping method for PEE based on multiple tuned mass dampers(MTMD).An MTMD damping device involving three mass units,named a triple tuned mass damper(TTMD),is designed and manufactured.Through shake table tests and finite element analysis,the dynamic characteristics of the PEE are studied and the effectiveness of the MTMD damping method is verified.The adverse influence of MTMD redundant mass to damping efficiency is studied and relevant equations are derived.MTMD robustness is verified through adjusting TTMD control frequencies.The damping effectiveness of TTMD,when the peak ground acceleration far exceeds the design value,is studied.Both shake table tests and finite element analysis indicate that MTMD is effective and robust in attenuating PEE seismic responses.TTMD remains effective when the PGA far exceeds the design value and when control deviations are considered. | Bai Wen Dai Junwu Zhou Huimeng Yang Yongqiang Ning Xiaoqing | 2017 | Earthquake Engineering and Engineering Vibration2017，16，4： | 8 |
| 6 | Monitoring Soil Salt Content Using HJ-1A Hyperspectral Data: A Case Study of Coastal Areas in Rudong County, Eastern China显示文摘Hyperspectral data are an important source for monitoring soil salt content on a large scale. However, in previous studies, barriers such as interference due to the presence of vegetation restricted the precision of mapping soil salt content. This study tested a new method for predicting soil salt content with improved precision by using Chinese hyperspectral data, Huan Jing-Hyper Spectral Imager(HJ-HSI), in the coastal area of Rudong County, Eastern China. The vegetation-covered area and coastal bare flat area were distinguished by using the normalized differential vegetation index at the band length of 705 nm(NDVI705). The soil salt content of each area was predicted by various algorithms. A Normal Soil Salt Content Response Index(NSSRI) was constructed from continuum-removed reflectance(CR-reflectance) at wavelengths of 908.95 nm and 687.41 nm to predict the soil salt content in the coastal bare flat area(NDVI705 < 0.2). The soil adjusted salinity index(SAVI) was applied to predict the soil salt content in the vegetation-covered area(NDVI705 ≥ 0.2). The results demonstrate that 1) the new method significantly improves the accuracy of soil salt content mapping(R2 = 0.6396, RMSE = 0.3591), and 2) HJ-HSI data can be used to map soil salt content precisely and are suitable for monitoring soil salt content on a large scale. | LI Jianguo PU Lijie ZHU Ming DAI Xiaoqing XU Yan CHEN Xinjian ZHANG Lifang ZHANG Runsen | 2015 | Chinese Geographical Science2015，25，2： | 4 |
| 7 | Synthesis of multifunctional monomers from rosin for the properties enhancement of soybean-oil based thermosets显示文摘Two kinds of rosin derivatives,(2-hydroxy-3-(methacryloyloxy)propyl 7-isopropyl-l,4a-dimethyl-1,2,3,4,4a,4b,5,6,10,10adecahydrophenanthrene-1-carboxylate)(HMPIDDC) and(((7-isopropyl-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydrophenanthren-l-yl)methyl)azanediyl)bis(2-hydroxypropane-3,l-diyl)bis(2-methylacrylate)(IDOMAHM) were synthesized under mild and easy to implement conditions.The two derivatives were employed as the rigid monomers to copolymerize with acrylated epoxidized soybean oil(AESO),as so to improve the performance of the cured resins.The chemical structures of HMPIDDC and IDOMAHM were confirmed by nuclear magnetic resonance(NMR) and Fourier Transform Infrared(FT-IR) before copolymerization.The curing behaviors of pristine AESO,AESO/HMPIDDC blend,and AESO/IDOMAHM blend were monitored by differential scanning calorimetry(DSC).Moreover,the thermal and mechanical properties of the cured resins were evaluated by universal mechanical testing,dynamic mechanical analysis(DMA) and thermogravimetric analysis(TGA).The results demonstrated that after the introduction of HMPIDDC and IDOMAHM,the glass transition temperature and mechanical properties of the copolymerized resin were significantly increased.In one word,HMPIDDC and IDOMAHM showed dramatic potential to be used as bio-based compounds to improve the properties of soybean-oil based thermosets. | LIU Yuan LI Chao DAI JinYue JIANG YanHua LIU XiaoQing ZHU Jin | 2017 | Science China(Technological Sciences)2017，60，9： | 3 |
| 8 | A novel in vitro angiogenesis model based on a microfluidic device显示文摘Angiogenesis is very important for many physiological and pathological processes. However, the molecular mechanisms of angiogenesis are unclear. To elucidate the molecular mechanisms of angiogenesis and to develop treatments for 'angiogenesis-dependent' diseases, it is essential to establish a suitable in vitro angiogenesis model. In this study, we created a novel in vitro angiogenesis model based on a microfluidic device. Our model provides an in vivo-like microenvironment for endothelial cells (ECs) cultures and monitors the response of ECs to changes in their microenvironment in real time. To evaluate the potential of this microfluidic device for researching angiogenesis, the effects of pro-angiogenic factors on ECs proliferation, migration and tube-like structure formation were investigated. Our results showed the proliferation rate of ECs in 3D matrix was significantly promoted by the pro-angiogenic factors (with an increase of 59.12%). With the stimulation of pro-angiogenic factors gradients, ECs directionally migrated into the Matrigel from low concentrations to high concentrations and consequently formed multi-cell chords and tube-like structures. These results suggest that the device can provide a suitable platform for elucidating the mechanisms of angiogenesis and for screening pro-angiogenic or anti-angiogenic drugs for 'angiogenesis-dependent' diseases. | DAI XiaoZhen CAI ShaoXi YE QunFang JIANG JiaHuan YAN XiaoQing XIONG Xin JIANG QiFeng WANG Albert Chih-Lueh TAN Yi | 2011 | Chinese Science Bulletin2011，56，31： | 3 |
| 9 | Re-Os Isotopic Age of Molybdenite of the Jingren Deposit and its Mineralogical Significance of Magnetite,Pyrite and Chalcopyrite显示文摘The Jingren deposit is part of the Qimantage metallogenic belt within the eastern Kunlun orogenic belt,the largest metallogenic belt in Qinghai Province,northwestern China.Exploration data show that the metal resources of the Jingren deposit are greater than 93000 t in a mining area of 76.15 km2,which indicates significant exploration potential in the near future.Three W–E-trending faults,F1-3,dominate the extension of the mineralization zone,which consists of chalcopyrite,pyrite,magnetite,galena,sphalerite,and molybdenite as well as bismuth-bearing minerals.The deposit contains a large amount of late Triassic intrusive rocks,however,previous research did not reach a consensus on the timing or the origin of the mineralization owing to a lack of geochronological data and poor exposure conditions.In the present study,Re-Os isotopic dating from six molybdenite samples collected from a borehole of the granodiorite in the Jingren deposit using negative thermal ionization mass spectrometry(NTIMS)showed 187 Re and 187 Os concentrations of 0.26–4.40 ppm and 1.03–16.46 ppb,respectively,with an initial 187 Os/188 Os value of 0.06±0.19.This proves that the Jingren deposit has a metallogenic age of(225±4)Ma and is the product of united mineralization of the Qimantage metallogenic belt and that the Jingren deposit might actually be an Indosinian metallogeny.In addition,the Re content of these samples,at 0.42 ppm to 7.00 ppm shows that the mineralization was derived mainly from a crustal source.Furthermore,electron probe microanalysis(EPMA)conducted on chalcopyrite obtained from 22 metallic mineral samples revealed(Fe+Cu)/S ratios of 1.801–1.947 with an average of 1.852,which is lower than the ideal value(1.875).Besides,the main ore body formed in a relatively higher temperature environment than the surrounding rocks in the Jingren deposit.These data indicate that the Jingren deposit formed in a metallogenic environment at lower temperature.Moreover,according to the TiO_(2)-Al_(2)O_(3)-(MgO+MnO)and TiO_(2)-Al_(2)O_(3)-MgO genetic classification diagram for magnetite,the Jingren deposit most likely belongs to the skarn family.In addition,the Co-Ni-As genetic classification diagram of the pyrite indicates sedimentary and skarn genetic characteristics. | CAO Li YI Liwen DAI Wei XIE Binggeng LI Xiaoqing LU Anhuai GU Xiangping | 2021 | Acta Geologica Sinica(English Edition)2021，95，4： | 1 |
| 10 | The effects oiF leadon transient outward currents of acutely dissociated rat dorsal rootganglia 显示文摘 | DAI Xiaoqing RUAN Diyun CHEN Jutao ei al | 2001 | Brain Res2001，904，： | 1 |
| 11 | A simple photonic- assisted micro-wave frequency measurement system based on MZI with tuable measurement range and high resolution显示文摘 | Dai Jian Xu Kun Sun Xiaoqing | 2010 | IEEE Photonics Technology Letters2010，22，15： | 1 |
| 12 | A novel 2D graphical representation of DNA sequences and its application 显示文摘 | DAI Qi LIU Xiaoqing WANG Tianming | 2006 | Journal of Molecular Graphics and Modelling2006，25，3： | 1 |
| 13 | Taurine May Prevent Diabetic Rats from Developing Cardiomyopathy also by Downregulating Angiotensin II Type2 Receptor Expression显示文摘 | Changyun Li Linsheng Cao Qiutang Zeng Xiaoqing Liu Yanzhou Zhang Tianran Dai Dongnan Hu Kai Huang Yong Wang Xiang Wang Dazhu Li Zhijian Chen Jiaming Zhang Yushu Li Ranjit Sharma | 2005 | Cardiovascular Drugs and Therapy2005，，2： | 1 |
| 14 | A low-energy ion spectrometer with half-space entrance for three-axis stabilized spacecraft显示文摘A low-energy ion spectrometer(LEIS) for use aboard three-axis stabilized spacecraft has been developed to measure ion energy per charge distribution in three-dimensional space with good energy-, angular-and temporal-resolutions. For the standard top-hat electrostatic analyzer used widely in space plasma detection, three-axis stabilized spacecraft makes it difficult to obtain complete coverage of all possible ion arrival directions. We have designed angular scanning deflectors supplementing to a cylindrically symmetric top-hat electrostatic analyzer to provide a half-space field of view as 360°×90°(–45°–+45°), and fabricated the LEIS flight model for detecting magnetospheric ions in geosynchronous orbit. The performance of this payload has been evaluated in detail by a series of simulation and environmental tests, and the payload has also been calibrated through laboratory experiments using a low-energy ion source. The results show that capabilities of the LEIS payload are in accordance with the requirements of a magnetospheric mission. | HU RenXiang SHAN Xu YUAN GuangYuan WANG ShuWen ZHANG WeiHang QI Wei CAO Zhe LI YiRen CHEN ManMing YANG XiaoPing WANG Bo SHAO SiPei LI Feng ZHONG XiaoQing FAN Dan HAO XinJun FENG ChangQing SU ZhenPeng SHEN ChengLong LI Xin DAI GuYue QIU BingLin PAN ZongHao LIU Kai XU ChunKai LIU ShuBin AN Qi ZHANG TieLong WANG YuMing CHEN XiangJun | 2019 | Science China(Technological Sciences)2019，62，6： | 1 |
| 15 | Capacity limitation of nuclear units in grid based on analysis of frequency regulation显示文摘在对系统稳定性和安全的力量格子姿势威胁的原子单位的增加的能力。负担骚乱可以引起单位的超速并且触发超速保护控制器(OPC ) 。阀门的重复行动在设备的安全上有强壮的影响并且可以导致力量系统的倒塌。基于频率规定的分析,为在格子的原子单位的数学模型在这份报纸被建立当负担骚乱发生时,模仿动态过程。OPC 的批评行动为单位作为安全操作的限制被建议。在频率规定的不同式样和在格子的原子单位的许可的能力之间的关系被讨论。这研究能帮助在格子估计原子单位的能力限制。 | Yiping DAI Pan JIANG Lin GAO Weimin KAN Xiaoqing XIAO Ge JIN | 2012 | Frontiers in Energy2012，6，2： | 1 |
| 16 | Effect of berberine on Staphylococcus epidermidis biofilm formation显示文摘 | Xiaoqing Wang Xiao Yao Zhen’an Zhu Tingting Tang Kerong Dai Irina Sadovskaya Sigrid Flahaut Said Jabbouri | 2008 | International Journal of Antimicrobial Agents2008，，1： | 1 |
| 17 | Resazurin as an indicator of reducing capacity for analyzing the physiologic status of deep-sea bacterium Photobacterium phosphoreum ANT-2200显示文摘Resazurin(RZ)is a weakly fl uorescent blue dye and can be reduced irreversibly to highly fl uorescent pink resorufi n(RF)that is reduced reversibly to colorless dihydroresorufi n(hRF)by photodeoxygenation,chemical reaction and reductive organic compounds produced through cell metabolism.Because of the reliable and sensitive fl uorescence-color change and noninvasive features,RZ has been used widely as a redox indicator in cell viability/proliferation assays for bacteria,yeast,and mammalian cells.However,RZ is used rarely for physiological characterization of marine microorganisms.Here,we developed a custom-made irradiation and absorption-analysis device to assess the reducing capacity and physiologic status of marine bacterial cultures.We measured the absorption spectra of RZ,RF,and hRF in the presence of the reducing compound Na 2 S and under visible-light irradiation.After establishing appropriate parameters,we monitored the color changes of RZ and its reduced derivatives to evaluate the coherence between reducing capacity,bioluminescence and growth of the deep-sea bacterium Photobacterium phosphoreum strain ANT-2200 under various conditions.Emission of bioluminescence is an oxidation process dependent upon cellular reducing capacity.Growth and bioluminescence of ANT-2200 cell cultures were impeded progressively with increasing concentrations of RZ,which suggested competition for reducing molecules between RZ at high concentration with reductive metabolism.Therefore,caution should be applied upon direct addition of RZ to growth media to monitor redox reactions in cell cultures.Analyses of the instantaneous reduction velocity of RZ in ANT-2200 cell cultures showed a detrimental eff ect of high hydrostatic pressure and high coherence between the reducing capacity and bioluminescence of cultures.These data clearly demonstrate the potential of using RZ to characterize the microbial metabolism and physiology of marine bacteria. | Jie DAI Hongzhi TANG Xuegong LI Claire-Lise SANTIN Wenpeng CUI Na LIU Xiaoqing QI Xuehua CUI Alain GROSSI Philippe NOTARESCHI Wei-Jia ZHANG Long-Fei WU | 2021 | Journal of Oceanology and Limnology2021，39，1： | 0 |
| 18 | Recrystallization effect on surface passivation of Hastelloy X alloy fabricated by laser powder bed fusion显示文摘Post-heat treatment is generally adopted in the additive manufacturing field due to its alleviation of high residual stress and modification of rapid-solidified multilevel heterogeneous microstructure,and the related performance of the heat-treated counterparts calls for a systemic investigation to build a criterion of the heat treatment procedure.In this work,we focus on the heat treatment effects on the recrystallization of the Hastelloy X alloy produced by the laser powder bed fusion(LPBF)method,and the related surface passivation of the heat-treated counterparts is meticulously assessed as well.Results show that the multilevel heterostructure for LPBF Hastelloy X alloy consists of sub-micro dislocation cell substructures with Cr/Mo elemental segregation,fine columnar grains,and periodically-distributed molten pools.After heat treatment,partially and fully recrystallized structures for LPBF Hastelloy X alloys were achieved at 1100 and 1200℃for 1 h,respectively.Furthermore,the as-built LPBF Hastelloy X alloy shows superior corrosion resistance while the heat-treated one(1100℃)exhibits the worst in the borate buffer solution.The growth of passive film exhibited a highly linear correlation with the nucleation process controlled by diffusion,and high dislocation density and low angle grain boundary decreased the diffusion coefficient of cation vacancies,augmenting the nucleation sites of the passive film and enhancing its growth rate.Moreover,the micro-galvanic effect resulting from the partially recrystallized microstructure actively facilitated the formation of inhomogeneous porous passive films,leading to the worst corrosion resistance. | Xing He Li Wang Decheng Kong Ruixue Li Wei Zhang Kunjie Dai Xiaoqing Ni Ketai He Chaofang Dong | 2023 | Journal of Materials Science & Technology2023，，32： | 0 |
| 19 | Saturation efficiency for detecting 1550 nm photons with a 2×2 array of Mo0.8Si0.2 nanowires at 2.2 K显示文摘Amorphous materials are attractive candidates for fabricating the superconducting nanowire single-photon detectors(SNSPDs) due to their superior tolerance and scalability over crystalline niobium nitride. However, the reduced superconducting transition temperature degenerates both operating temperature and saturation efficiency. Herein, the SNSPD(6.5 nm thickness and 50 nm width) based on the amorphous Mo0.8Si0.2 film with a high optical absorption coefficient demonstrates close-to-unity intrinsic detection efficiency for 1550 nm photons from 75 m K to 2.2 K. Further, a high-performance array SNSPD with optimized 90 nm-width wires is also demonstrated. As-fabricated uniform 4-pixel SNSPD exhibits a saturation plateau for the photon counts at 2.2 K,which overcomes the limitation of operation at low temperature(< 1 K) for traditional amorphous SNSPDs.Coupled with superior intrinsic quantum efficiency, highly efficient photon counts, and low dark count ratio, this detector paves a way for achieving high efficiency and superior yield for large array systems. | Feiyan Li Hang Han Qi Chen Biao Zhang Han Bao Yue Dai Rui Ge Shuya Guo Guanglong He Yue Fei Shuchao Yang Xiaohan Wang Hao Wang Xiaoqing Jia Qingyuan Zhao Labao Zhang Lin Kang Peiheng Wu | 2021 | Photonics Research2021，9，3： | 0 |
| 20 | Phosphorus-doped iron-nitrogen-carbon catalyst with pentacoordinated single atom sites for efficient oxygen reduction显示文摘Single-atomic Fe-N4 is the well-acknowledged active site in iron-nitrogen-carbon(Fe-N-C)material for oxygen reduction reaction(ORR).The adjusting of the electronic distribution of Fe-N4 is promising for further enhancing the performance of the Fe-N-C catalyst.Herein,a phosphorus(P)-doped Fe-N-C catalyst with penta-coordinated single atom sites(FeNPC)is reported for efficient oxygen reduction.Fe K-edge X-ray absorption spectroscopy(XAS)verifies the coordination environment of single Fe atom,while density functional theory(DFT)calculations reveal that the penta-coordination and neighboring doped P atoms can simultaneously change the electronic distribution of Fe-N_(4)and its adsorption strength of key intermediates,reducing the reactionfree energy of the potential-limiting step.Electrochemical tests validate the remarkable intrinsic ORR activity of FeNPC in alkaline media(a half-wave potential(E_(1/2))of 0.904 V vs.reversible hydrogen electrode(RHE)and limited current density(JL)of 6.23 mA·cm^(−2))and an enhanced ORR performance in neutral(E_(1/2)=0.751 V,J_(L)=5.27 mA·cm^(−2))and acidic media(E_(1/2)=0.735 V,JL=5.82 mA·cm^(−2))with excellent stability,highlighting the benefits of optimizing the local environment of singleatomic Fe-N4. | Lili Fan Xiaofei Wei Xuting Li Zhanning Liu Mengfei Li Shuo Liu Zixi Kang Fangna Dai Xiaoqing Lu Daofeng Sun | 2023 | Nano Research2023，16，2： | 0 |
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