|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Reemergent Cases of COVID-19—Xinfadi Wholesales Market,Beijing Municipality,China,June 11,2020显示文摘No new local coronavirus disease 2019(COVID-19)cases were reported in Beijing for over 56 days before the reemergent COVID-19 cases that were reported on June 11,2020,and more than 200 confirmed cases have been reported as of June 20 in Beijing.All confirmed COVID-19 cases were associated with Xinfadi Wholesale Market.Here,we reported the phylogenetic characteristics of the COVID-19 viruses(also known as severe acute respiratory syndrome coronavirus 2,SARS-CoV-2,and human coronavirus 2019,HCoV-19)sequenced from the clinical specimens of 2 human cases and 1 environmental sample. | Wenjie Tan Peihua Niu Xiang Zhao Yang Pan Yong Zhang Lijuan Chen Li Zhao Yanhai Wang Dayan Wang Jun Han George FGao Chun Huang Wenbo Xu Guizhen Wu | 2020 | China CDC weekly2020，2，27： | 6 |
| 2 | microRNAs as oncogenes and tumor suppressors显示文摘 | Baohong Zhang Xiaoping Pan George P. Cobb Todd A. Anderson | 2006 | Developmental Biology2006，，1： | 5 |
| 3 | The temporal dynamics of antimicrobial-resistant Salmonella enterica and predominant serovars in China显示文摘Salmonella enterica is one of the most common bacterial pathogens in humans and animals.Systematic studies on the trends and geographical distribution of antimicrobial-resistant Salmonella and dominant serovars have been well studied in European and American countries while not in China.Here,taking the One-Health strategy,we used>35000 Salmonella enterica isolates to explore the temporal and spatial dynamics of dominant serovars in China.We found that Salmonella Typhimurium was the dominant serovar causing human infection in China,which was consistent with Australia but inconsistent with North American and European countries.The proportion of Salmonella serovars Typhimurium,London,Rissen,Corvallis,Meleagridis,Kentucky,and Goldcoast showed an increasing trend during 2006-2019.We randomly selected 1962 isolates for comparative genomics and antimicrobial resistance studies and found that the number of antibiotic resistance genes(ARGs)per isolate increased 1.84 and 2.69 times of human and non-human origins,respectively,spanning 14 years.The proportion of antimicrobial-resistant Salmonella isolates had an increasing trend during 2006-2019,especially beta-lactam,quinolone,tetracycline,and rifampicin resistance.Moreover,we found that higher diversity of sequence types(STs)in S.Typhimurium than in other serovars,ST34 from pig and ST 19 from chicken origin,were mainly associated with isolates causing child and adult gastro-infection,respectively.Our results fill in the data gap on the trends of dominant serovars and antimicrobial resistance of Salmonella enterica in China.These data provide useful information for public health decision-makers prioritizing interventions for foodborne diseases and food safety. | Yanan Wang Yue Liu Na Lyu Zhiyuan Li Sufang Ma Demin Cao Yuanlong Pan Yongfei Hu Hua Huang George F.Gao Xuebin Xu Baoli Zhu | 2023 | National Science Review2023，10，3： | 4 |
| 4 | LIN28 coordinately promotes nucleolar/ribosomal functions and represses the 2C-like transcriptional program in pluripotent stem cells显示文摘LIN28 is an RNA binding protein with important roles in early embryo development,stem cell differentiation/re-programming,tumorigenesis and metabolism.Previous studies have focused mainly on its role in the cytosol where it interacts with Let-7 microRNA precursors or mRNAs,and few have addressed LIN28's role within the nucleus.Here,we show that LIN28 displays dynamic temporal and spatial expression during murine embryo development.Maternal LIN28 expression drops upon exit from the 2-cell stage,and zygotic LIN28 protein is induced at the forming nucleolus during 4-cell to blas-tocyst stage development,to become dominantly expressed in the cytosol after implantation.In cultured pluripotent stem cells(PSCs),loss of LIN28 led to nucleolar stress and activation of a 2-cell/4-cell-like transcriptional program characterized by the expression of endogenous retrovirus genes.Mechanistically,LIN28 binds to small nucleolar RNAs and rRNA to maintain nucleolar integrity,and its loss leads to nucleolar phase separation defects,ribosomal stress and activation of P53 which in turn binds to and activates 2C transcription factor Dux.LIN28 also resides in a complex containing the nucleolar factor Nucleolin(NCL)and the transcrip-tional repressor TRIM28,and LIN28 loss leads to reduced occupancy of the NCL/TRIM28 complex on the Dux and rDNA loci,and thus de-repressed Dux and reduced rRNA expression.Lin28 knockout cells with nucleolar stress are more likely to assume a slowly cycling,translationally inert and anabolically inactive state,which is a part of previously unappreciated 2C-like transcriptional program.These findings elucidate novel roles for nucleolar LIN28 in PSCs,and a new mechanism linking 2C program and nucleolar functions in PSCs and early embryo development. | Zhen Sun Hua Yu Jing Zhao Tianyu Tan Hongru Pan Yuqing Zhu Lang Chen Cheng Zhang Li Zhang Anhua Lei Yuyan Xu Xianju Bi Xin Huang Bo Gao Longfei Wang Cristina Correia Ming Chen Qiming Sun Yu Feng Li Shen Hao Wu Jianlong Wang Xiaohua Shen George Q.Daley Hu Li Jin Zhang | 2022 | Protein & Cell2022，13，7： | 4 |
| 5 | Spatial Analysis of People Living with HIV/AIDS Transmitted Through Commercial Heterosexual Contact or Non-Marital Non-Commercial Heterosexual Contact—China,2018显示文摘Summary What is already known about this topic?Significant changes in human immunodeficiency virus(HIV)transmission modes have occurred in China,and the proportion of heterosexual transmission increased in recent years.What is added by this report?The proportions of diverse transmission routes and subgroups of heterosexual transmission were analyzed by provincial-level administrative divisions(PLADs). | Zhilong Dong Xiaohong Pan Chang Cai Qianqian Qin George F.Gao Fan Lyu | 2021 | China CDC weekly2021，3，15： | 3 |
| 6 | 室内装修用特制定向刨花板显示文摘本文介绍了一种加拿大产特制定向刨花板,该板材是为室内装修和家具制造而特制的,通过对其生产原材料、生产工艺特点、产品性能的分析,并就该产品在室内装修领域进行了探讨,期望室内设计师、家具设计师和用户对该特制定向刨花板有全新的认识。 | 许斌 詹先旭 陈立衡 Kenneth Lau George Pan | 2014 | 家具2014，35，6： | 3 |
| 7 | The first pulsar discovered by FAST显示文摘To assist with the commissioning [1] of the Five-hundredmeter Aperture Spherical radio Telescope (FAST), we performed a pulsar search, with the primary goal of developing and testing the pulsar data acquisition and processing pipelines. We tested and used three pipelines, two (Pl and P2 hereafter) searched for the periodic signature of pulsars whereas the other one was used to search for bright single pulses (P3 hereafter). | Lei Qian ZhiChen Pan Di Li George Hobbs WeiWei Zhu Pei Wang ZhiJie Liu YouLing Yue Yan Zhu HongFei Liu DongJun Yu JingHai Sun Peng Jiang GaoFeng Pan Hui Li HengQian Gan Rui Yao XiaoYao Xie Fernando Camilo Andrew Cameron Lei Zhang Shen Wang FAST Collaboration | 2019 | Science China(Physics,Mechanics & Astronomy)2019，62，5： | 3 |
| 8 | THE NCEP CLIMATE FORECAST SYSTEM REANALYSIS显示文摘 | Saha Suranjana Moorthi Shrinivas Pan Hua-Lu Wu Xingren Wang Jiande Nadiga Sudhir Tripp Patrick Kistler Robert Woollen John Behringer David Liu Haixia Stokes Diane Grumbine Robert Gayno George Wang Jun Hou Yu-Tai Chuang Hui-ya Juang Hann- | 2010 | Bulletin of the American Meteorological Society2010，，8： | 2 |
| 9 | Plant microRNA: A small regulatory molecule with big impact显示文摘 | Baohong Zhang Xiaoping Pan George P. Cobb Todd A. Anderson | 2005 | Developmental Biology2005，，1： | 2 |
| 10 | The bleachability of wheat straw alkaline peroxide mechanical pulp显示文摘 | Pan George X Leary Gordon J | 2000 | Cellulose chemistry and technology2000，34，56： | 1 |
| 11 | A novel two-step coprecipitation process using Fe(III) and Al(III) for the removal and immobilization of arsenate from acidic aqueous solution显示文摘 | Yongfeng Jia Danni Zhang Rongrong Pan Liying Xu George P. Demopoulos | 2011 | Water Research2011，，2： | 1 |
| 12 | Histone deacetylase inhibi- tots facilitate dihydroartemisinin - induced apoptosis in liver canc- er in vitro and in vivo显示文摘 | Chris ZZ Pan YH George GC | 2012 | Plos One2012，7，39： | 1 |
| 13 | Wavelet based deconvolution algorithm for time-domain near-field ISAR imaging显示文摘 | Guangwen Pan Jui-Yi Lin George Cheng | 2007 | IEEE Transactions on Antennas and Propagation2007，55，7： | 1 |
| 14 | Assessing Respiration-Induced Tumor Motion and Internal Target Volume Using Four-Dimensional Computed Tomography for Radiotherapy of Lung Cancer显示文摘 | H. Helen Liu Peter Balter Teresa Tutt Bum Choi Joy Zhang Catherine Wang Melinda Chi Dershan Luo Tinsu Pan Sandeep Hunjan George Starkschall Isaac Rosen Karl Prado Zhongxing Liao Joe Chang Ritsuko Komaki James D. Cox Radhe Mohan Lei Dong | 2007 | International Journal of Radiation Oncology Biology Physics2007，，2： | 1 |
| 15 | Targeting of syndecan‐1 by microRNA miR‐10b promotes breast cancer cell motility and invasiveness via a Rho‐GTPase‐ and E‐cadherin‐dependent mechanism显示文摘 | Sherif A. Ibrahim George W. Yip Christian Stock Jun‐Wei Pan Claudia Neubauer Michaela Poeter Danute Pupjalis Chuay Yeng Koo Reinhard Kelsch Roland Schüle Ursula Rescher Ludwig Kiesel Martin G?tte | 2012 | Int J Cancer2012，，6： | 1 |
| 16 | Identification of cotton microRNAs and their targets显示文摘 | Baohong Zhang Qinglian Wang Kunbo Wang Xiaoping Pan Fang Liu Tenglong Guo George P. Cobb Todd A. Anderson | 2007 | Gene2007，，1： | 1 |
| 17 | Assessing Respiration-Induced Tumor Motion and Internal Target Volume Using Four-Dimensional Computed Tomography for Radiotherapy of Lung Cancer显示文摘 | H. Helen Liu Peter Balter Teresa Tutt Bum Choi Joy Zhang Catherine Wang Melinda Chi Dershan Luo Tinsu Pan Sandeep Hunjan George Starkschall Isaac Rosen Karl Prado Zhongxing Liao Joe Chang Ritsuko Komaki James D. Cox Radhe Mohan Lei Dong | 2007 | International Journal of Radiation Oncology Biology Physics2007，，2： | 1 |
| 18 | MicroRNAs as oncogenes and tumor suppressors 显示文摘 | ZHANG Bao-hong PAN Xiao-ping GEORGE P | 2007 | De- velopmental Biology2007，302，1： | 1 |
| 19 | The Combination of Calmodulin Antagonists and Interferon-γ Induces Apoptosis through Caspase-Dependent and -Independent Pathways in Cholangiocarcinoma Cells显示文摘 | Eun-Young Ahn George Pan Jae Hwan Oh Ewan M. Tytler Jay M. McDonald | 2003 | The American Journal of Pathology2003，，5： | 1 |
| 20 | Low cost carriers’ destination selection using a Delphi method显示文摘 | Yu-Chun Chang Chia-Jui Hsu George Williams Mei-Ling Pan | 2007 | Tourism Management2007，，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员