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| 1 | Characteristics of volatile organic compounds,NO_2,and effects on ozone formation at a site with high ozone level in Chengdu显示文摘Chengdu is a megacity in the southwest of China with high ozone(O_3) mixing ratio.Observation of volatile organic compounds(VOCs), NO_2 and O_3 with high temporal resolution was conducted in Chengdu to investigate the chemical processes and causes of high O_3 levels. The hourly mixing ratios of VOCs, NO2, and O_3 were monitored by an online system from 28 August to 7 October, 2016. According to meteorological conditions,Chengdu, with relative warm weather and low wind speed, is favorable to O_3 formation.Part of the O_3 in Chengdu may be transported from the downtown area. In O_3 episodes,the average mixing ratios of NO_2 and O_3 were 20.20 ppbv and 47.95 ppbv, respectively. In non-O_3 episodes, the average mixing ratios of NO_2 and O_3 were 16.38 ppbv and 35.15 ppbv,respectively. The average mixing ratio of total VOCs(TVOCs) was 40.29 ppbv in non-O_3 episodes, which was lower than that in O_3 episodes(53.19 ppbv). Alkenes comprised51.7% of the total O_3 formation potential(OFP) in Chengdu, followed by aromatics which accounted for 24.2%. Ethylene, trans-pentene, propene, and BTEX(benzene, ethylbenzene,toluene, m/p-xylene, o-xylene) were also major contributors to the OFP in Chengdu. In O_3 episodes, intensive secondary formations were observed during the campaign. Oxygenated VOCs(OVOCs), such as acetone, Methylethylketone(MEK), and Methylvinylketone(MVK)were abundant. Isoprene rapidly converted to MVK and Methacrolein(MACR) during O_3 episodes. Acetone was mainly the oxidant of C3-C5 hydrocarbons. | Yuanyuan Deng Jing Li Yaqi Li Rongrong Wu Shaodong Xie | 2019 | Journal of Environmental Sciences2019，31，1： | 29 |
| 2 | Effect of scraping therapy on Interleukin-1 in serum of rats with lumbar disc herniation显示文摘OBJECTIVE:To explore the effect of scraping therapy on the Interleukin-1 (IL-1) levels of rats with lumbar disc herniation (LDH). METHODS: Fifty male rats were devided into a blank group (A), a sham operation group (B), a model group (C), a scraping group (D), and a drug group (E). The rats in the group B were treated with sham operation, and groups C, D and E were made into the LDH model by operation. After operation group C were treated with no interventions, D were given scraping and E were fed with azathioprine Then the IL-1 levels of different groups were detected by enzyme-linked immuno sorbent assay method. And the transplanted coccygeal vertebra discs were observed by pathological section. RESULTS: The IL-1 levels in the groups C, D, and E were significantly higher than those in the groups A and B (all P<0.01), which proved the operationwas successful.The IL-1 levels in the groups D and E at different periods had statistical significance (F= 414.158, P<0.01). The treatment periods and interventions have interation (F=46.613, P<0.01). Multiple comparison results showed that the IL-1 levels in the groups D and E was significantly lower than that in the group C (P<0.01), while the IL-1 levels between the groups D and E had no statistical significance (P>0.05). Moreover, pathological section indicated that immuno-inflammatory response was hardly found in coccygeal vertebra discs in the groups A and B, while local immuno-inflammatory responses of the groups D and E were much lighter than that of the group C. CONCLUSION: Scraping therapy could inhibit the immuno-inflammatory responses in the rats with LDH caused by transplantation of autologous nu cleus pulposus. | Rongrong Jiang Guihua Xu Hua Chen Jie Li Tao Yang Yang Guo | 2013 | Journal of Traditional Chinese Medicine2013，33，1： | 23 |
| 3 | Exome sequencing confirms molecular diagnoses in 38 Chinese families with hereditary spherocytosis显示文摘Hereditary spherocytosis(HS), the most common cause of congenital hemolytic anemia, is caused by deficiency of the erythrocyte membrane proteins. Five causative genes(ANK1, SPTB, SPTA1, SLC4 A1, and EPB42) have been identified. To date,molecular genetic studies have been performed in different populations, including the American, European, Brazilian, Japanese and Korean populations, whereas only a few studies have been described in the Chinese population. Here, by reanalysis of the exome data, we revealed causative mutations and established a definitive diagnosis of HS in all 38 Chinese families. We found 34 novel mutations and four reported mutations in three known HS-causing genes—17 in ANK1, 17 in SPTB and four in SLC4 A1,suggesting that ANK1 and SPTB are the major genes in Chinese patients with HS. All of the ANK1 or SPTB mutations, scattered throughout the entire genes, are non-recurrent; and most of them are null mutations, which might cause HS via a haploinsufficiency mechanism. De novo mutations in ANK1 or SPTB often occur with an unexpected high frequency(87.5% and64.2%, respectively). Our study updates our knowledge about the genetic profile of HS in Chinese and shows that family-based,especially parent-offspring trio, sequencing analysis can help to increase the diagnostic power and improve diagnostic efficiency. | Rongrong Wang Shuanghao Yang Ming Xu Jia Huang Hongyan Liu Weiyue Gu Xue Zhang | 2018 | Science China(Life Sciences)2018，61，8： | 22 |
| 4 | Trends in particulate matter and its chemical compositions in China from 2013–2017显示文摘Accurate determination of the atmospheric particulate matter mass concentration and chemical composition is helpful in exploring the causes and sources of atmospheric enthalpy pollution and in evaluating the rationality of environmental air quality control strategies.Based on the sampling and chemical composition data of PM2.5 in different key regions of China in the CARE-China observation network,this research analyzes the environmental air quality data released by the China National Environmental Monitoring Centre during the studied period to determine the changes in the particulate matter mass concentration in key regions and the evolution of the corresponding chemical compositions during the implementation of the Action Plan for Prevention and Control of Air Pollution from 2013-2017.The results show the following.(1)The particulate matter mass concentration in China showed a significant downward trend;however,the PM2.5 annual mass concentration in 64%of cities exceeds the New Chinese Ambient Air Quality Standard(CAAQS)GradeⅡ(GB3095-2012).The region to the east of the Taihang Mountains,the Fenhe and Weihe River Plain and the Urumqi-Changji regions in Xinjiang,all have PM2.5 concentration loading that is still high,and heavy haze pollution occurred frequently in the autumn and winter.(2)During the heavy pollution in the autumn and winter,the concentrations of sulfate and organic components decreased significantly.The mean SO42-concentration in PM2.5 decreased by 76%,12%,81%and 38%in Beijing-Tianjin-Hebei(BTH),the Pearl River Delta(PRD),the Sichuan-Chongqing region(SC)and the Fenhe and Weihe River Plain,respectively.The mean organic matter(OM)concentration decreased by 70%,44%,48%and 31%,respectively,and the mean concentration of NH4+decreased by 68%,1.6%,38%and 25%,respectively.The mean elemental carbon(EC)concentration decreased by 84%and 20%in BTH and SC,respectively,and it increased by 61%and 11%in the PRD and Fenhe and Weihe River Plain,respectively.The mean concentration of mineral and unresolved chemical components(MI)dropped by 70%,24%and 13%in BTH,the PRD and the Fenhe and Weihe River Plain,respectively.The change in the PM2.5 chemical composition is consistent with the decrease of the PM2.5mass concentration.(3)In 2015,the mean OM concentration contributions to fine particles and coarse particles were 13-46%and 46-57%,respectively,and the mean MI concentration contributions to fine particles and coarse and particles were 31-60%and 39-73%,respectively;these values are lower than the 2013 values from the key regions,which is the most important factor behind the decrease of the particulate matter mass concentration.From 2013 to 2015,among the chemical components of different particle size fractions,the peak value of the coarse particle size fraction decreased significantly,and the fine particle size fractions of SO42-,NO3-,and NH4+decreased with the decrease of the particulate matter mass concentration in different particle size fractions.The fine-particle size peaks of SO42-,NO3-and NH4+shifted from 0.65-1.1μm to the finer size range of0.43-0.65μm during the same time frame. | Yuesi WANG Wenjie LI Wenkang GAO Zirui LIU Shili TIAN Rongrong SHEN Dongsheng JI Shuai WANG Lili WANG Guiqian TANG Tao SONG Mengtian CHENG Gehui WANG Zhengyu GONG Jiming HAO Yuanhang ZHANG | 2019 | Science China Earth Sciences2019，62，12： | 23 |
| 5 | Size,composition,and mixing state of individual aerosol particles in a South China coastal city显示文摘Aerosol samples were collected in summer in Macao,a coastal city of the Pearl River Delta Region in China.Morphology,size,elemental composition,and mixing state of individual aerosol particles were determined by scanning electron microscopy coupled energy dispersive X-ray(SEM/EDX) and transmission electron microscopy(TEM).Based on the morphologies of 5711 aerosol particles,they consist of soot(32%),mineral(17%),secondary(22%),and unknown fine particles(29%).The sizes of these particles were mostly distributed between 0.1 and 0.4 μm.Compositions of 202 mineral particles were obtained by SEM/EDX.Mineral particles were mainly classified into three types:Si-rich,Ca-rich,and Na-rich.The compositions of typical mineral particles can indicate their sources in sampling location.For example,mineral particles,collected along the main street,were associated with trace amounts of heavy metals,such as Zn,Ti,Mn,Ba,Pb,and As.TEM observations indicate that most Na-rich particles were aged sea salt particles(e.g.,Na2SO4 and NaNO3) which formed through heterogeneous chemical reactions between sea salt and acidic gases.Additionally,aging time of soot was short in Macao due to high humidity,high temperature,and high levels of sunlight in Macao.Most of soot and fine mineral dust particles were internally mixed with secondary particles. | Weijun Li Longyi Shao Zhishi Wang Rongrong Shen Shusheng Yang Uwa Tang | 2010 | Journal of Environmental Sciences2010，22，4： | 21 |
| 6 | Petrogenesis of Indosinian Granitoids in Middle-Segment of South Qinling Tectonic Belt:Constraints from Sr-Nd Isotopic Systematics显示文摘南方 Qinling 构造的带(SQTB ) 在 Shangzhou-Danfeng 和 Mianxian-Lueyang 缝术之间被定位。在它的中间的片断有很多早中生代 granitoid plutons,包括在在西南的东北,在中央部分的 Huayang-Wulong-Laocheng granitoid plutons,在西北的 Xiba granitoid pluton 和 Guangtoushan-Liuba granitoid plutons 的 Dongjiangkou-Zhashui granitoid plutons。这些 Indonisian granitoids 包含各种各样的规模 mafic 被外国领地包围的土地的一个团,它与他们的主人 granitoids 显示出有时清楚的边界和有时过渡的边界。这些 granitoids 也从 low-K tholeiite 系列展出 metaluminous 到 peraluminous 系列,通常更高的 Mg# 和大量石油化学,通过 mid-K 和 high-K,到 shoshonite 系列的计算碱的系列和支配的样品被归因于 mid-K 和 high-K 计算碱的系列。在 Sr-Nd 同位素的 systematics 和石油化学的详细分析表明可以有 Indonisian granitoid plutons 的地区性起始的 granitoid 岩浆,包括 Dongjiangkou-Zhashui , Huayang-Wulong-Laocheng , Xiba ,和 Guangtoushan-Liuba granitoid plutons ,它被岩浆的混血儿在各种各样的度生产,并且起始的岩浆在 SQTB 从披风和更低的大陆人外壳( LCC )来源被导出。起始的 granitoid 岩浆进一步在他们的炮兵阵地期间与上面的外壳的材料从 LCC,结晶化分别,和吸收做了与岩浆混合的岩浆在 SQTB 生产这些 granitoid plutons。这些 magmatism 过程是最可能的发生在大陆下面边缘的弧和 syn 碰撞到碰撞以后的构造背景。 | LIU Shuwen LI Qiugen TIAN Wei WANG Zongqi YANG Pengtao WANG Wei BAI Xiang GUO Rongrong | 2011 | Acta Geologica Sinica(English Edition)2011，85，3： | 20 |
| 7 | Non-stationary water-level fluctuation in China's Poyang Lake and its interactions with Yangtze River显示文摘Seasonal water-level fluctuations(WLF) play a dominate role in lacustrine ecosystems. River-lake interaction is a direct factor in changes of seasonal lake WLF, especially for those lakes naturally connected to upstream and downstream rivers. During the past decade, the modification of WLF in the Poyang Lake(the largest freshwater lake in China) has caused intensified flood and irrigation crises, reduced water availability, compromised water quality and extensive degradation of the lake ecosystem. There has been a conjecture as to whether the modification was caused by its interactions with Yangtze River. In this study, we investigated the variations of seasonal WLF in China's Poyang Lake by comparing the water levels during the four distinct seasons(the dry season, the rising season, the flood season, and the retreating season) before and after 2003 when the Three Gorge Dam operated. The Water Surface Slope(WSS) was used as a representative parameter to measure the changes in river-lake interaction and its impacts on seasonal WLF. The results showed that the magnitude of seasonal WLF has changed considerably since 2003; the seasonal WLF of the Poyang Lake have been significantly altered by the fact that the water levels both rise and retreat earlier in the season and lowered water levels in general. The fluctuations of river-lake interactions, in particular the changes during the retreating season, are mainly responsible for these variations in magnitude of seasonal WLF. This study demonstrates that WSS is a representative parameter to denote river-lake interactions, and the results indicate that more emphasis should be placed on the decrease of the Poyang Lake caused by the lowered water levels of the Yangtze River, especially in the retreating season. | DAI Xue WAN Rongrong YANG Guishan | 2015 | Journal of Geographical Sciences2015，25，3： | 18 |
| 8 | miR-218 suppresses the metastasis and EMT of HCC cells via tar qeting SERBP1显示文摘Hepatocellular 癌(HCC ) 是世界范围的癌症相关的死亡的领先的原因。尽管为对待 HCC 的许多努力被作了,幸存率仍然保持未得到满足。积累的证据显示 microRNA-218 (miR-218 ) 作为肿瘤 suppressor 工作并且在人的癌症的某些类型在象肿瘤开始,开发,和转移那样的许多生物进程包含。然而,潜在的功能和在 HCC 的 miR-218 的内在的分子的机制尚待被阐明。自从 HCC,是基因疾病,探索致病原因的机制,集成为为 HCC 的新奇治疗目标的发现是必要的。因此,现在的学习的目的是在临床的 HCC 纸巾和 HCC 房间调查 miR-218 的反常表达式水平,并且在 HCC 评估它的函数和内在的机制。我们的结果表明那 miR-218 表情是显著地,在 HCC 纸巾和房间的 downregulated 排队。Gain-of-function 和 loss-of-function 试金显示在 HCC 房间的 miR-218 的那强迫的表情禁止了房间迁居 / 侵略并且颠倒了上皮间充质的转变(EMT ) 到间充质上皮的转变(相遇) ,当 miR-218 的删除支持了房间迁居 / 侵略并且贡献了 EMT 显型形成时。生物信息学分析和酶记者试金证实(SERBP1 ) serpine mRNA 绑定蛋白质 1 是 miR-218 的目标基因,营救试金进一步证实了在 HCC 涉及 miR-218 的函数的那 SERBP1。所有这些结果建议 miR-218/SERBP1 信号小径能禁止恶意的显型形成并且指向这条小径可以是为 HCC 治疗学的一个潜在的新奇方法。 | Ting Wang Ling Xu Rongrong Jia Jue Wei | 2017 | Acta Biochimica et Biophysica Sinica2017，49，5： | 17 |
| 9 | Using Fuzzy Theory and Variable Weights for Water Quality Evaluation in Poyang Lake, China显示文摘Achieving water purity in Poyang Lake has become a major concern in recent years, thus appropriate evaluation of spatial and temporal water quality variations has become essential. Variations in 11 water quality parameters from 15 sampling sites in Poyang Lake were investigated from 2009 to 2012. An integrative fuzzy variable evaluation(IFVE) model based on fuzzy theory and variable weights was developed to measure variations in water quality. Results showed that: 1) only chlorophyll-a concentration and Secchi depth differed significantly among the 15 sampling sites(P < 0.01), whereas the 11 water quality parameters under investigation differed significantly throughout the seasons(P < 0.01). The annual variations of all water quality variables except for temperature, electrical conductivity, suspended solids and total phosphorus were considerable(P < 0.05). 2) The IFVE model was reasonable and flexible in evaluating water quality status and any possible ′bucket effect′. The model fully considered the influences of extremely poor indices on overall water quality. 3) A spatial analysis indicated that anthropogenic activities(particularly industrial sewage and dredging) and lake bed topography might directly affect water quality in Poyang Lake. Meanwhile, hydrological status and sewage discharged into the lake might be responsible for seasonal water quality variations. | LI Bing YANG Guishan WAN Rongrong ZHANG Lu ZHANG Yanhui DAI Xue | 2017 | Chinese Geographical Science2017，27，1： | 15 |
| 10 | Comparative biomechanical study of reversed less invasive stabilization system and proximal femoral nail antirotation for unstable intertrochanteric fractures显示文摘 | Chen Ying Liu Shouyao Lin Peng Wang Yunting Wang Jinhui Tao Jianfeng Cai Rongrong | 2014 | Chinese Medical Journal2014，，23： | 13 |
| 11 | Fe/Fe2O3 nanoparticles anchored on Fe-N-doped carbon nanosheets as bifunctional oxygen electrocatalysts for rechargeable zinc-air batteries显示文摘有高催化的活动和稳定性玩的 Electrocatalysts 在有希望的可更新的精力技术的一个关键角色,例如燃料房间和金属空气电池。这里,我们报导 Fe/Fe 2 O 3 nanoparticles 在 Fe-N-doped 碳 nanosheets 上抛锚了(Fe/Fe 2 导出壳的做 N 的碳 nanodots 由一条简单热分解途径面对 FeCl 3 作为碳和氮采购的 O 3@Fe-N-C) 使用虾。Fe/Fe 2 O 3@Fe-N-C 在 1,000 的热分解温度获得了 ??????????? ″ ? 猼灵资 ? ??( ?? | Yipeng Zang Haimin Zhang Xian Zhang Rongrong Liu Shengwen Liu Guozhong Wang Yunxia Zhang Huijun Zhao | 2016 | Nano Research2016，9，7： | 10 |
| 12 | Design and performance analysis of position-based impedance control for an electrohydrostatic actuation system显示文摘Electrohydrostatic actuator(EHA) is a type of power-by-wire actuator that is widely implemented in the aerospace industry for flight control, landing gears, thrust reversers, thrust vector control, and space robots. This paper presents the development and evaluation of positionbased impedance control(PBIC) for an EHA. Impedance control provides the actuator with compliance and facilitates the interaction with the environment. Most impedance control applications utilize electrical or valve-controlled hydraulic actuators, whereas this work realizes impedance control via a compact and efficient EHA. The structures of the EHA and PBIC are firstly introduced. A mathematical model of the actuation system is established, and values of its coefficients are identified by particle swarm optimization. This model facilitates the development of a position controller and the selection of target impedance parameters. A nonlinear proportional-integral position controller is developed for the EHA to achieve the accurate positioning requirement of PBIC. The controller compensates for the adverse effect of stiction, and a position accuracy of 0.08 mm is attained.Various experimental results are presented to verify the applicability of PBIC to the EHA. The compliance of the actuator is demonstrated in an impact test. | Yongling FU Xu HAN Nariman SEPEHRI Guozhe ZHOU Jian FU Liming YU Rongrong YANG | 2018 | Chinese Journal of Aeronautics2018，31，3： | 10 |
| 13 | High degree of pharmacokinetic compatibility exists between the five-herb medicine XueBiJing and antibiotics comedicated in sepsis care显示文摘Managing the dysregulated host response to infection remains a major challenge in sepsis care. Chinese treatment guideline recommends adding Xue Bi Jing, a five-herb medicine, to antibioticbased sepsis care. Although adding Xue Bi Jing further reduced 28-day mortality via modulating the host response, pharmacokinetic herbedrug interaction is a widely recognized issue that needs to be studied.Building on our earlier systematic chemical and human pharmacokinetic investigations of Xue Bi Jing, we evaluated the degree of pharmacokinetic compatibility for Xue Bi Jing/antibiotic combination based on mechanistic evidence of interaction risk. Considering both Xue Bi Jing-antibiotic and antibiotic-Xue Bi Jing interaction potential, we integrated informatics-based approach with experimental approach and developed a compound pair-based method for data processing. To reflect clinical reality, we selected for study Xue Bi Jing compounds bioavailable for drug interactions and 45 antibiotics commonly used in sepsis care in China. Based on the data of interacting with drug metabolizing enzymes and transporters, no Xue Bi Jing compound could pair, as perpetrator, with the antibiotics. Although some antibiotics could,due to their inhibition of uridine 50-diphosphoglucuronosyltransferase 2 B15, organic anion transporters1/2 and/or organic anion-transporting polypeptide 1 B3, pair with senkyunolide I, tanshinol and salvianolic acid B, the potential interactions(resulting in increased exposure) are likely desirable due to these Xue Bi Jing compounds’ low baseline exposure levels. Inhibition of aldehyde dehydrogenase by 7 antibiotics probably results in undesirable reduction of exposure to protocatechuic acid from Xue Bi Jing.Collectively, Xue Bi Jing/antibiotic combination exhibited a high degree of pharmacokinetic compatibility at clinically relevant doses. The methodology developed can be applied to investigate other drug combinations. | Jian Li Olajide E.Olaleye Xuan Yu Weiwei Jia Junling Yang Chuang Lu Songqiao Liu Jingjing Yu Xiaona Duan Yaya Wanga Kai Dong Rongrong He Chen Cheng Chuan Li | 2019 | Acta Pharmaceutica Sinica B2019，9，5： | 10 |
| 14 | Biogeographic distribution patterns of algal community in different urban lakes in China: Insights into the dynamics and co-existence显示文摘Urban lake ecosystems are significant for social development,but currently we know little about the geographical distribution of algal community in urban lakes at a large-scale.In this study,we investigated the algal community structure in different areas of urban lakes in China and evaluated the influence of water quality parameters and geographical location on the algal community.The results showed that obvious differences in water quality and algal communities were observed among urban lakes in different geographical areas.Chlorophyta was the dominant phylum,followed by cyanobacteria in all areas.The network analysis indicated that algal community composition in urban lakes of the western and southern area showed more variations than the eastern and northern areas,respectively.Redundancy analysis and structural equation model revealed that nutrients and p H were dominant environmental factors that affected the algal community,and they showed higher influence than that of iron,manganese and COD Mn concentration.Importantly,algal community and density exhibited longitude and latitude relationship.In general,these results provided an ecological insight into large-scale geographical distributions of algal community in urban lakes,thereby having potential applications for management of the lakes. | Haihan Zhang Rongrong Zong Huiyan He Kaiwen Liu Miaomiao Yan Yutian Miao Ben Ma Xin Huang | 2021 | Journal of Environmental Sciences2021，33，2： | 9 |
| 15 | The synergistic effect of resveratrol in combination with cisplatin on apoptosis via modulating autophagy in A549 cells显示文摘几研究证明了有自然产品和化疗代理人的联合治疗能改进化疗代理人的 sensitivityand cytotoxicity。Resveratrol,一个自然产品,包括 antitumor andantiviral 活动,以及脉管的保护的效果有许多生物效果。这研究的目的是与 cisplatin 和涉及 A549 房间的潜在的 anticancer 机制在联合调查 resveratrol 的 synergistic anticancereffect。从数 Kit-8 和 isobolographic 分析的房间的 resultsobtained 表明了 resveratrol 和 cisplatin resultedin synergistic 的那联合在 A549 房间的细胞毒素的效果。从染色的 Hoechst 的结果,流动 cytometry 和西方的污点分析 suggestedthat resveratrol 提高了调停 cisplatin 的 apoptosis。同时, LC3-II 和 P62 层次和在有 cisplatin 的联合的 resveratrol 触发了的 autophagosomesuggested 的形成的变化 autophagy。更重要地,由 3-methyladeninemarkedly 禁止 autophagy 稀释了 resveratrol 和 cisplatin 的联合在 A549 房间引起的 apoptosis。一起拿,我们的 studyprovides resveratrol synergistically 与 cisplatin 相结合的第一条证据在 A549 房间经由 modulating autophagiccell 死亡导致 apoptosis。这些调查结果也帮助我们在肺癌症与 chemotherapyagents 在联合理解自然产品的角色。 | Song Hu Xiaolin Li Rongrong Xu Lingyun Ye Hui Kong Xiaoning Zeng Hong Wang Weiping Xie | 2016 | Acta Biochimica et Biophysica Sinica2016，48，6： | 9 |
| 16 | Qualitative analysis of chemical components in Lianhua Qingwen capsule by HPLC-Q Exactive-Orbitrap-MS coupled with GC-MS显示文摘The Lianhua Qingwen(LHQW) capsule is a popular traditional Chinese medicine for the treatment of viral respiratory diseases.In particular,it has been recently prescribed to treat infections caused by the severe acute respiratory syndrome coronavirus 2(SARS-CoV-2).However,due to its complex composition,little attention has been directed toward the analysis of chemical constituents present in the LHQW capsule.This study presents a reliable and comprehensive approach to characterizing the chemical constituents present in LHQW by high-performance liquid chromatography-Q Exactive-Orbitrap mass spectrometry(HPLC-Q Exactive-Orbitrap-MS) coupled with gas chromatography-mass spectrometry(GC-MS).An automated library alignment method with a high mass accuracy(within 5 ppm) was used for the rapid identification of compounds.A total of 104 compounds,consisting of alkaloids,flavonoids,phenols,phenolic acids,phenylpropanoids,quinones,terpenoids,and other phytochemicals,were successfully characterized.In addition,the fragmentation pathways and characteristic fragments of some representative compounds were elucidated.GC-MS analysis was conducted to characterize the volatile compounds present in LHQW.In total,17 compounds were putatively characterized by comparing the acquired data with that from the NIST library.The major constituent was menthol,and all the other compounds were terpenoids.This is the first comprehensive report on the identification of the major chemical constituents present in the LHQW capsule by HPLC-Q Exactive-Orbitrap-MS,coupled with GCMS,and the results of this study can be used for the quality control and standardization of LHQW capsules. | Shuai Fu Rongrong Cheng Zixin Deng Tiangang Liu | 2021 | Journal of Pharmaceutical Analysis2021，11，6： | 8 |
| 17 | Influence of Land Use/Cover Change on Storm Runoff—A Case Study of Xitiaoxi River Basin in Upstream of Taihu Lake Watershed显示文摘Land use/cover change (LUCC) is one of the main boundary conditions which influence many hydrologic processes. In view of the importance of Taihu Lake Watershed in China and the urgency of discovering the impacts of LUCC on storm runoff, two flood events under five land cover scenarios in the Xitiaoxi River Basin of the upstream of Taihu Lake watershed were simulated by distributed hydrologic modeling system HEC-HMS. The influences of each land cover on storm runoff were discussed. It was concluded that under the same rainstorm the ascending order of runoff coefficient and peak flow produced by the 5 different land covers were woodland, shrub, grassland, arable land, and built-up land; the descending order of swelling time were woodland, shrub, grassland, arable land, and built-up land. Scenario of built-up land was the first to reach peak flow, then arable land, grassland, shrub, and woodland. There were close relationships between the runoff coefficients produced by the 5 different land covers. The degrees of impacts on runoff coefficient of land cover change modes were sorted by descending: woodland to built-up land, shrub to built-up land, grassland to built-up land, arable land to built-up land, woodland to arable land, shrub to arable land, arable land to grassland, shrub to grassland, grassland to arable land, and woodland to shrub. Urbanization will contribute to flood disaster, while forestation will mitigate flood disaster. | WAN Rongrong YANG Guishan | 2007 | Chinese Geographical Science2007，17，4： | 8 |
| 18 | Genetic diversity and DNA fingerprinting in jute(Corchorus spp.) based on SSR markers显示文摘Genetic diversity analysis and DNA finger printing are very useful in breeding programs,seed conservation and management. Jute(Corchorus spp.) is the second most important natural fiber crop after cotton. DNA fingerprinting studies in jute using SSR markers are limited. In this study, 58 jute accessions, including two control varieties(Huangma 179 and Kuanyechangguo) from the official variety registry in China were evaluated with 28 pairs of SSR primers. A total of 184 polymorphic loci were identified. Each primer detected 3 to 15 polymorphic loci, with an average of 6.6. The 58 jute accessions were DNA-fingerprinted with 67 SSR markers from the 28 primer pairs. These markers differentiated the 58 jute accessions from one another, with Co SSR305-120 and Co SSR174-195 differentiating Huangma 179 and Kuanyechangguo, respectively. NTSYS-pc2.10 software was used to analyze the genetic diversity in the 58 jute accessions. Their genetic similarity coefficients ranged from 0.520 to 0.910 with an average of 0.749, indicating relatively great genetic diversity among them. The 58 jute accessions were divided into four groups with the coefficient 0.710 used as a value for classification, consistent with their species and pedigrees. All these results may be useful both for protection of intellectual property rights of jute accessions and for jute improvement. | Liwu Zhang Rongrong Cai Minhang Yuan Aifen Tao Jiantang Xu Lihui Lin Pingping Fang Jianmin Qi | 2015 | The Crop Journal2015，3，5： | 8 |
| 19 | Applications of aptamers for chemistry analysis, medicine and food security显示文摘Since aptamer and its in vitro selection process called SELEX were independently described by Ellington and Gold in 1990, extensive research has been undertaken and numerous isolated aptamers for various targets have been applied. Aptamers can bind to a wide range of targets that include small organic molecules, inorganic compounds, haptens and even whole cells with high binding affinity and specificity. Aptamers for a wide range of targets have been selected currently. In addition, aptamers are thermo stable and can also be regenerated easily within a few minutes denaturation, which makes them easy to store or handle. These advantages make aptamers extremely suitable for applications based on molecular recognition as analytical, diagnostic and therapeutic tools. In this review, the recent applications of aptamers for chemistry analysis, medicine and food security, along with the future trend will be discussed. | Rongrong Huang Zhijiang Xi Nongyue He | 2015 | Science China Chemistry2015，58，7： | 7 |
| 20 | RST transforms resistant image watermarking based on centroid and sector-shaped partition显示文摘A novel digital watermarking scheme featuring centroid-based sectoring is proposed in this paper. To get higher robustness against geometric attacks, such as rotation, scaling, and translation (RST), a delicate synchronization mechanism was developed and incorporated into the proposed approach. During the process of watermark embedding, the original image was partitioned into sectors based on the image centroid. Synchronization information as well as the message bits is then embedded into these sectors. With the help of the centroid-based sectoring and synchronization information, the proposed approach is capable of restoring the correct sectoring even if it has experienced severe geometric distortion. This attribute ensures the correct recovery of embedded watermarks and contributes to the robustness of the proposed scheme. A series of experiments have been conducted to verify the feasibility and effectiveness of the proposed approach. Experimental results show that the proposed scheme possesses good robustness against RST attacks and considerable robustness against other common image processing attacks. | ZHAO Yao NI RongRong ZHU ZhenFeng | 2012 | Science China(Information Sciences)2012，55，3： | 7 |
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