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| 1 | Jagged-1/Notch3 signaling transduction pathway is involved in apelin-13-induced vascular smooth muscle cells proliferation显示文摘apelin/apelin 受体(APJ, apelinangiotensin 像受体 1 ) 系统是一最新 deorphanized G 联合蛋白质的受体系统。是重要规章的因素的 apelin 和 APJ 在心血管的系统被表示。我们的以前的研究显著地表明了那 apelin-13 刺激脉管的光滑的肌肉房间(VSMC ) 增长。在这份报纸,我们的数据建议表明 transduction 小径的 Jagged-1/Notch3 被支持 Cyclin D1 的表示涉及 apelin-13-induced VSMC 增长。结果显示 apelin-13 在集中依赖者和时间依赖者礼貌刺激 VSMC 和 Jagged-1 和 Notch3 的表示的增长。apelin-13 导致的 Jagged-1 和 Notch3 的增加的表示能被细胞外的调整信号的蛋白质 kinase (英皇家空军之阶级最低之兵) 废除封锁。PD98059 (英皇家空军之阶级最低之兵禁止者) 能禁止 apelin-13 导致的 Jagged-1/Notch3 的激活。用小介入 RNA 的 Notch3 的下面规定禁止 Cyclin D1 的表示并且阻止 apelin-13-induced VSMC 增长。在结论, Jagged-1/Notch3 发信号 transduction 小径涉及 apelin-13 导致的 VSMC 增长。 | Lifang Li Lanfang Li Feng Xie Zidong Zhang Yu Guo Guotao Tang Deguan Lv Qixuan Lu Linxi Chen Jian Li | 2013 | Acta Biochimica et Biophysica Sinica2013，45，10： | 18 |
| 2 | RRVPE:A Robust and Real-Time Visual-Inertial-GNSS Pose Estimator for Aerial Robot Navigation显示文摘Self-localization and orientation estimation are the essential capabilities for mobile robot navigation.In this article,a robust and real-time visual-inertial-GNSS(Global Navigation Satellite System)tightly coupled pose estimation(RRVPE)method for aerial robot navigation is presented.The aerial robot carries a front-facing stereo camera for self-localization and an RGB-D camera to generate 3D voxel map.Ulteriorly,a GNSS receiver is used to continuously provide pseudorange,Doppler frequency shift and universal time coordinated(UTC)pulse signals to the pose estimator.The proposed system leverages the Kanade Lucas algorithm to track Shi-Tomasi features in each video frame,and the local factor graph solution process is bounded in a circumscribed container,which can immensely abandon the computational complexity in nonlinear optimization procedure.The proposed robot pose estimator can achieve camera-rate(30 Hz)performance on the aerial robot companion computer.We thoroughly experimented the RRVPE system in both simulated and practical circumstances,and the results demonstrate dramatic advantages over the state-of-the-art robot pose estimators. | ZHANG Chi YANG Zhong XU Hao LIAO Luwei ZHU Tang LI Guotao YANG Xin ZHANG Qiuyan | 2023 | Wuhan University Journal of Natural Sciences2023，28，1： | 2 |
| 3 | PEGylated PAMAM dendrimers as a potential drug delivery carrier:in vitro and in vivo comparative evaluation of covalently conjugated drug and noncovalent drug inclusion complex显示文摘 | Jiang YanYan Tang GuoTao Zhang LiHong | 2010 | J Drug Target2010，5，18： | 1 |
| 4 | Facile Synthesis of Yolk–Shell Structured Inorganic–Organic Hybrid Spheres with Ordered Radial Mesochannels显示文摘 | Zhaogang Teng Shouju Wang Xiaodan Su Guotao Chen Ying Liu Zhimin Luo Wei Luo Yuxia Tang Huangxian Ju Dongyuan Zhao Guangming Lu | 2014 | Adv Mater2014，，22： | 1 |
| 5 | Biophysical studies on the differentiation of human CD14+ monocytes into dendritic cells显示文摘 | Zhu Zeng Xiao Liu Yuhui Jiang Guotao Wang Jun Zhan Jun Guo Weijuan Yao Dagong Sun Weibo Ka Yan Tang Junming Tang Zongyao Wen Shu Chien | 2006 | Cell Biochemistry and Biophysics2006，，1： | 1 |
| 6 | PEGylated PAMAM Dendrimer-Doxorubicin Conjugates: In Vitro Evaluation and In Vivo Tumor Accumulation显示文摘 | Saijie Zhu Minghuang Hong Lihong Zhang Guotao Tang Yanyan Jiang Yuanying Pei | 2010 | Pharmaceutical Research2010，，： | 1 |
| 7 | Hf-doped ZnO transistor with high bias stability and high field-effect mobility by modulation of oxygen vacancies and interfaces显示文摘ZnO-based thin film transistors(TFTs)with high bias stability are challenging due to the intrinsic defects and overhigh interface trap density.In this work,we fabricated Hf-doped ZnO films with different cycle ratio of Zn/Hf via atomic layer deposition and subsequent annealing treatment.The results show that the cycle ratio of Zn/Hf is optimized to be 10:1,and the corresponding atomic ratio is 2.24%.The threshold voltage and subthreshold swing of the devices are improved as the annealing temperature increases,owning to the decrease of the oxygen vacancies and interface trap density.Furthermore,we developed Hf-doped ZnO TFT with high bias stability by introducing HfO_(2)intermediate layer between the active layer and SiO_(2)dielectric layer,and the shift of threshold voltage is as low as-0.273 V,showing high bias stability.Also,the device has the high field-effective mobility of 52.4 cm^(2)/Vs,low subthreshold swing of 0.68 V/dec and high Ion/Ioff of 3.6×10^(8).The results indicate a promising fabrication method for highperformance ZnO-based TFTs,which may be applied in logic circuits,radio frequency identification and so on. | Yushu Tang Pengwei Tan Yuanyuan Luo Zheng Zhang Liyang Luo Guotao Duan | 2023 | Journal of Materials Science & Technology2023，，32： | 0 |
| 8 | Xixiang Biota——Another Rare Scientific Window of the Cambrian Explosion显示文摘Objective The Xixiang biota is a specially preserved micro oryctocoenose discovered in the Lower Cambrian Kuanchuanpu member of Dengying Formation at Zhangjiagou section of Xixiang County in southern Shaanxi Province.The Kuanchuanpu member is a set of neritic carbonate sedimentary formation containing phosphorus and silicon.Its lithology is mainly | LIU Yunhuan WANG Qi SHAO Tiequan DONG Junyan TANG Hanhua ZHANG Yanan JIANG Kaituo HU Bo WANG Zhaojing PANG Guotao MA Yingying FAN Ziyang | 2016 | Acta Geologica Sinica(English Edition)2016，90，3： | 0 |
| 9 | Genesis of the Nuri Cu-W-Mo Deposit,Tibet,China:Constraints from in situ Trace Elements and Sr Isotopic Analysis of Scheelite显示文摘The Nuri deposit is the only Cu-W-Mo polymetallic deposit with large-scale WO3 resources in the eastern section of the Gangdese metallogenic belt,Tibet,China.However,the genetic type of this deposit has been controversial since its discovery.Based on a study of the geological characteristics of the deposit,this study presents mineralization stages,focusing on the oxide stage and the quartz-sulfide stage where scheelite is mainly formed,referred to as Sch-A and Sch-B,respectively.Through LA-ICP-MS trace element and Sr isotope analyses,the origin,evolutionary process of the oreforming fluid and genesis of the ore deposit are investigated.Scanning Electron Microscope-Cathodoluminescence(SEMCL)observations reveal that Sch-A consists of three generations,with dark gray homogenous Sch-A1 being replaced by relatively lighter and homogeneous Sch-A2 and Sch-A3,with Sch-A2 displaying a gray CL image color with vague and uneven growth bands and Sch-A3 has a light gray CL image color with hardly any growth band.In contrast,Sch-B exhibits a‘core-rim’structure,with the core part(Sch-B1)being dark gray and displaying a uniform growth band,while the rim part(Sch-B2)is light gray and homogeneous.The normalized distribution pattern of rare earth elements in scheelite and Sr isotope data suggest that the early ore-forming fluid in the Nuri deposit originated from granodiorite porphyry and,later on,some country rock material was mixed in,due to strong water-rock interaction.Combining the O-H isotope data further indicates that the ore-forming fluid in the Nuri deposit originated from magmatic-hydrothermal sources,with contributions from metamorphic water caused by water-rock interaction during the mineralization process,as well as later meteoric water.The intense water-rock interaction likely played a crucial role in the precipitation of scheelite,leading to varying Eu anomalies in different generations of scheelite from the oxide stage to the quartz-sulfide stage,while also causing a gradual decrease in oxygen fugacity(fO2)and a slow rise in pH value.Additionally,the high Mo and low Sr contents in the scheelite are consistent with typical characteristics of magmatic-hydrothermal scheelite.Therefore,considering the geological features of the deposit,the geochemical characteristics of scheelite and the O-H isotope data published previously,it can be concluded that the genesis of the Nuri deposit belongs to porphyry-skarn deposit. | WANG Yiyun WU Zhishan CHEN Wenqing DU Qing’an TANG Liwei SHI Hongzhao MA Guotao ZHANG Zhi LIANG Wei WU Bo MIAO Hengyi | 2024 | Acta Geologica Sinica(English Edition)2024，98，1： | 0 |
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