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| 1 | Age-related rhesus macaque models of COVID-19显示文摘Background:Since December 2019,an outbreak of the Corona Virus disease 2019(COVID-19)caused by severe acute respiratory syndrome coronavirus(SARS-CoV-2)in Wuhan,China,has become a public health emergency of international concern.The high fatality of aged cases caused by SARS-CoV-2 was a need to explore the possible age-related phenomena with non-human primate models.Methods:Three 3-5 years old and two 15 years old rhesus macaques were intratracheally infected with SARS-CoV-2,and then analyzed by clinical signs,viral replication,chest X-ray,histopathological changes and immune response.Results:Viral replication of nasopharyngeal swabs,anal swabs and lung in old monkeys was more active than that in young monkeys for 14 days after SARS-CoV-2 challenge.Monkeys developed typical interstitial pneumonia characterized by thickened alveolar septum accompanied with inflammation and edema,notably,old monkeys exhibited diffuse severe interstitial pneumonia.Viral antigens were detected mainly in alveolar epithelial cells and macrophages.Conclusion:SARS-CoV-2 caused more severe interstitial pneumonia in old monkeys than that in young monkeys.Rhesus macaque models infected with SARS-CoV-2 provided insight into the pathogenic mechanism and facilitated the development of vaccines and therapeutics against SARS-CoV-2 infection. | Pin Yu Feifei Qi Yanfeng Xu Fengdi Li Peipei Liu Jiayi Liu Linlin Bao Wei Deng Hong Gao Zhiguang Xiang Chong Xiao Qi Lv Shuran Gong Jiangning Liu Zhiqi Song Yajin Qu Jing Xue Qiang Wei Mingya Liu Guanpeng Wang Shunyi Wang Haisheng Yu Xing Liu Baoying Huang Wenling Wang Li Zhao Huijuan Wang Fei Ye Weimin Zhou Wei Zhen Jun Han Guizhen Wu Qi Jin Jianwei Wang Wenjie Tan Chuan Qin | 2020 | Animal Models and Experimental Medicine2020，3，1： | 22 |
| 2 | The partial pressure of carbon dioxide and air-sea fluxes in the Changjiang River Estuary and adjacent Hangzhou Bay显示文摘The distributions of partial pressure of carbon dioxide (p CO2 ) in the surface waters of the Changjiang River Estuary and adjacent Hangzhou Bay were examined in the summer of 2010. Surface water p CO2 ranged from 751-2 095 μatm (1 atm=101 325 Pa) in the inner estuary, 177-1 036 μatm in the outer estuary, and 498-1 166 μatm in Hangzhou Bay. Overall, surface p CO2 behaved conservatively during the estuary mixing. In the inner estuary, surface p CO2 was relatively high due to urbanized pollution and a high respiration rate. The lowest p CO2 was observed in the outer estuary, which was apparently induced by a phytoplankton bloom because the dissolved oxygen and chlorophyll a were very high. The Changjiang River Estuary was a significant source of atmospheric CO2 and the degassing fluxes were estimated as 0-230 mmol/(m2 d) [61 mmol/(m2 d) on average] in the inner estuary. In contrast, the outer estuary acted as a CO2 sink. | YU Peisong ZHANG Haisheng ZHENG Minhui PAN Jianming BAI Yan | 2013 | Acta Oceanologica Sinica2013，32，6： | 8 |
| 3 | Bipartite consensus of edge dynamics on coopetition multi-agent systems显示文摘Dear editor,The cooperative control of multi-agent systems has attracted wide attention from scholars in various fields because of its wide applications.The controllability and consensus problem of multi-agent systems are two basic issues,which have been widely studied in recent years[1-4]. | Lei TIAN Zhijian JI Ting HOU Haisheng YU | 2019 | Science China(Information Sciences)2019，62，12： | 8 |
| 4 | Whole-genome sequencing provides insights into the genetic diversity and domestication of bitter gourd(Momordica spp.)显示文摘Bitter gourd(Momordica charantia)is a popular cultivated vegetable in Asian and African countries.To reveal the characteristics of the genomic structure,evolutionary trajectory,and genetic basis underlying the domestication of bitter gourd,we performed whole-genome sequencing of the cultivar Dali-11 and the wild small-fruited line TR and resequencing of 187 bitter gourd germplasms from 16 countries.The major gene clusters(Bi clusters)for the biosynthesis of cucurbitane triterpenoids,which confer a bitter taste,are highly conserved in cucumber,melon,and watermelon.Comparative analysis among cucurbit genomes revealed that the Bi cluster involved in cucurbitane triterpenoid biosynthesis is absent in bitter gourd.Phylogenetic analysis revealed that the TR group,including 21 bitter gourd germplasms,may belong to a new species or subspecies independent from M.charantia.Furthermore,we found that the remaining 166 M.charantia germplasms are geographically differentiated,and we identified 710,412,and 290 candidate domestication genes in the South Asia,Southeast Asia,and China populations,respectively.This study provides new insights into bitter gourd genetic diversity and domestication and will facilitate the future genomics-enabled improvement of bitter gourd. | Junjie Cui Yan Yang Shaobo Luo Le Wang Rukui Huang Qingfang Wen Xiaoxia Han Nansheng Miao Jiaowen Cheng Ziji Liu Changyuan Zhang Chengcheng Feng Haisheng Zhu Jianwen Su Xinjian Wan Fang Hu Yu Niu Xiaoming Zheng Yulan Yang Dai Shan Zhensheng Dong Weiming He Narinder P.S.Dhillon Kailin Hu | 2020 | Horticulture Research2020，7，1： | 7 |
| 5 | Biomarker records in penguin droppings and observed changes in penguin communities and their response to the ENSO in the Western Antarctic显示文摘Lipid biomarkers in AD2 penguin droppings-amend soil core from the Ardley Island,Western Antarctic,were dated using 210Pb.Changes in the fatty acid ratios of nC18:2/nC18:0 from the penguin droppings reflect climate changes coincident with ENNO events during 1931-2006.The occurrence of the minimum values in the depth of 2-3 and 6-7 cm are consistent with the end of ENSO in 1958 and 1983,respectively,reflecting a lag of the biomarker records in AD2 penguin droppings-amend soil in climatic signatures.This study also reveals that the changes in the relative concentration of n-alkanes nC23,the ratios of nC23/nC17 and nC21 /nC22+,and carbon preferential index(CPI) values collectively indicate the variations of soil microor-ganism and lower plant,which are closely related to climate changes.The ratios of bacterial fatty acids iC15:0/aC15:0 reflect the increasing significance of microorganism activities during the two periods that occurred at the end years of ENSO.Decrease in CPIA value and increase in nC21 /nC22+ indicate that low molecular weight fatty acids are derived from microorganism;and their insignificant correlation with Pr/Ph suggests microorganisms play an important role in the relatively simply ecosystem in the Antarctic and are closely linked to climatic conditions.In addition,the observed penguin community indicates the popula-tion of penguin can largely reflect the impacts of global climate changes on the ecosystem. | ZHANG HaiSheng LU DouDing YU PeiSong ZHANG WeiGuo LU Bing Hans-Ulrich PETER Walter VETTER | 2012 | Science China Earth Sciences2012，55，8： | 6 |
| 6 | Human BDCA2^+CD123^+CD56^+ dendritic cells (DCs) related to blastic plasmacytoid dendritic cell neoplasm represent a unique myeloid DC subset显示文摘树枝状的房间(DC ) 包括二个机能上地不同的子集:plasmacytoid DC (pDCs ) 和 myeloid DC (mDCs ) 。pDCs 被专攻类型的快速、巨大的分泌物我响应通过使用费的 nucleic 酸的干扰素(IFN-I ) 相似受体(TLR )-7 或 TLR-9。在这份报告,我们描绘了 CD56 < 啜 class= “ a-plus-plus ” >+ DC 人口包括 CD123 和 BDCA2 表示典型 pDC 标记,但是生产与 pDCs 作比较的少得多 IFN-I。另外, CD56 < 啜 class= “ a-plus-plus ” > 和由介绍的染色体宽的 transcriptional 的 mDCs 然而并非 pDCs 的 + DC 簇。因此, CD56 < 啜 class= “ a-plus-plus ” >+ DC 机能上地由在 TLR4 刺激和 priming na 之上生产 IL-12 类似于 mDCs ? 没有优先的激活的 ve T 房间。这些数据建议 CD56 < 啜 class= “ a-plus-plus ” >+ DC 代表与一些 pDC 特征混合的一个新奇 mDC 子集。CD4 < 啜 class= “ a-plus-plus ” >+ CD56 < 啜 class= “ a-plus-plus ” >+ hematological 恶意作为 blastic plasmacytoid 被分类树枝状的房间瘤(BPDCN ) 由于它 pDCs 的典型分子的表示。然而,我们证明 BPDCN 接近 CD56 < 啜 class= “ a-plus-plus ” >+ DC 比由介绍的全球基因表示的 pDCs。因此,我们建议 CD4 < 啜 class= “ a-plus-plus ” >+ CD56 < 啜 class= “ a-plus-plus ” >+ 瘤可以是 CD56 的一个肿瘤对应物 < 啜 class= “ a-plus-plus ” >+ mDCs 然而并非 pDCs。 | Haisheng Yu Peng Zhang Xiangyun Yin Zhao Yin QuanxinG Shi Ya Cui Guanyuan Liu Shouli Wang Pier Paolo Piccaluga Taijiao Jiang Liguo Zhang | 2015 | Protein & Cell2015，6，4： | 6 |
| 7 | Robust YAG:Ce single crystal for ultra-high efficiency laser lighting显示文摘At present,solid-state laser-driven lighting fabricated with blue laser diode(LD)and phosphor has been greatly developed in high-power lighting applications.The major obstacle is the luminescence saturation threshold of the fluorescence conversion material(YAG:Ce).In this work,we successfully prepared a series of high-quality and robust YAG:Ce single crystals.With high quantum efficiency(QE=92%),regular crystal structure and high thermal conductivity,the single-crystal has excellent ability to deal with high radiation flux and thermal accumulation generated by high power.Matching the single-crystal with the laser,the luminous efficiency up to 274 lm/W and saturation threshold of 12 W/mm^(2) were obtained.In addition,the influence of Ce doping concentration and sample processing conditions on the indicators in laser-driven white lighting was systematically studied.The results are of great significance and are believed to promote the development of solid-state laser-driven lighting. | Yaqian Zhang Jianming Liu Yujie Zhang Haisheng Yang Yanxia Yu Qingyun He Xiaojuan Liang Yongfu Liu Weidong Xiang | 2022 | Journal of Rare Earths2022，40，5： | 5 |
| 8 | Purification of starch and phosphorus wastewater using core-shell magnetic seeds prepared by sulfated roasting显示文摘Core-shell magnetic seeds with certain adsorption capacity that were prepared by sulfated roasting, served as the core of a magnetic separation technology for purification of starch wastewater. XRD and SEM results indicate that magnetite's surface transformed to be porous α-Fe_2O_3 structure. Compared with magnetite particles, the specific surface area was significantly improved to be 8.361 from 2.591 m^2/g, with little decrease in specific susceptibility. Zeta potential, FT-IR and XPS experiments indicate that both phosphate and starch adsorbed on the surface of the core-shell magnetic seeds by chemical adsorption, which fits well with the Langmuir adsorption model. The porous surface structure of magnetic seeds significantly contributes to the adsorption of phosphate and starch species, which can be efficiently removed to be 1.51 mg/L(phosphate) and 9.51 mg/L(starch) using magnetic separation. | Chunjie Du Jinsheng Yu Wei Sun Haisheng Han Yuehua Hu Pan Chen Panpan Hou Runqing Liu Li Wang Yue Yang Ruohua Liu Lei Sun | 2019 | Journal of Environmental Sciences2019，31，7： | 4 |
| 9 | Concentrations and distribution of biogenic barium in surface sediments of Prydz Bay,Antarctica显示文摘Concentrations of biogenic barium were investigated in surface sediments of Prydz Bay,Antarctica,during the 21st and27th CHINARE cruises.Factors controlling the observed distribution are explored.Biogenic barium concentrations obtained from a sequential extraction procedure are compared with total concentrations obtained from the normative calculation based on a total digestion,and differences in the results are examined.Concentrations of biogenic barium,calculated by the normative calculation,were much higher than the concentrations obtained through sequential extraction;this discrepancy is the result of the occurrence of barium associated with Mn/Fe oxides,which represents an important component of total barium in these sediments.Concentrations of biogenic barium obtained from the sequential extraction range from 104 to 445μg·g^(-1),and the average concentration was227μg·g^(-1).The highest concentrations of biogenic barium occur in the central area of the bay,where the seawater is more stable,while lower values occur in the bank and the ice shelf.Biogenic barium is significantly linearly correlated with biogenic barium and organic carbon,and similar in distribution of Chl a,which may indicate that primary productivity of phytoplankton in the surface water column is the main environmental factor regulating barium concentration and distribution. | TAN Saizhang YU Peisong HU Chuanyu HAN Zhengbing ZHANG Haisheng | 2013 | Advances in Polar Science2013，24，3： | 1 |
| 10 | Passivity-Based Control of PMSM Based on State Error PCH Method and PI Regulation显示文摘 | Yu Haisheng Yu Jinpeng Liu Xudong | 2011 | ICIC Express Letters2011，5，8： | 1 |
| 11 | Adap-tire fuzzy tracking control for the chaotic permanent magnet synchronous motor drive system via backstepping 显示文摘 | Jinpeng Yu Bing Chen Haisheng Yu Junwei Gao | 2011 | Non- linear Analysis-Real World Applications2011，12，1： | 1 |
| 12 | Single or dual sourcing: decision-making in the presence of supply chain disruption risks显示文摘 | Haisheng Yu Amy Z. Zeng Lindu Zhao | 2008 | Omega2008，，4： | 1 |
| 13 | Control Strategy Design and Experimental Research on a Four-Shaft Electronic Continuously Variable Transmission Hybrid Electric Vehicle显示文摘 | Yu Haisheng Zhang Jianwu Zhang Tong | 2012 | Proceedings of the Institution of Mechanical Engineers Part D: Journal of Auto- mobile Engineering2012，226，12： | 1 |
| 14 | Novel high-entropy oxides for energy storage and conversion:From fundamentals to practical applications显示文摘High-entropy oxides(HEOs)are gaining prominence in the field of electrochemistry due to their distinctive structural characteristics,which give rise to their advanced stable and modifiable functional properties.This review presents fundamental preparations,incidental characterizations,and typical structures of HEOs.The prospective applications of HEOs in various electrochemical aspects of electrocatalysis and energy conversion-storage are also summarized,including recent developments and the general trend of HEO structure design in the catalysis containing oxygen evolution reaction(OER)and oxygen reduction reaction(ORR),supercapacitors(SC),lithium-ion batteries(LIBs),solid oxide fuel cells(SOFCs),and so forth.Moreover,this review notes some apparent challenges and multiple opportunities for the use of HEOs in the wide field of energy to further guide the development of practical applications.The influence of entropy is significant,and high-entropy oxides are expected to drive the improvement of energy science and technology in the near future. | Zi-Yu Liu Yu Liu Yujie Xu Hualiang Zhang Zongping Shao Zhenbin Wang Haisheng Chen | 2023 | Green Energy & Environment2023，8，5： | 1 |
| 15 | Analyzing the evolutionary stability of the vendor-managed inventory supply chains显示文摘 | Haisheng Yu Amy Z. Zeng Lindu Zhao | 2008 | Computers & Industrial Engineering2008，，1： | 1 |
| 16 | Phytoplankton and chlorophyll a relationships with ENSO in Prydz Bay, East Antarctica显示文摘The historical data of phytoplankton and chlorophyll a(Chl a)(1990–2002)obtained during the Chinese National Antarctic Research Expedition(CHINARE)in the Prydz Bay have been integrated.The results showed that the temperature,salinity,nutrients,and oxygen of seawater changed when El Nino/La Nina occurred.The variation of biological communities reflected the response of ecosystem to environmental changes.During El Ni?o period,Chl a concentration and phytoplankton community structure changed significantly,and the relative proportion of diatoms increased while dinoflagellates decreased.During La Ni?a period,the proportion of diatoms decreased,but the golden-brown algae and blue-green algae increased significantly.The variation of phytoplankton population directly affected the biodiversity of the bay,which were also quite sensitive to the marine environment changes.Meanwhile,the satellite remote sensing data of 2002–2011(December–March)have been used to study the temporal connection change of Chl a and phytoplankton in the Prydz Bay.We found that there were significant differences in the monthly variation characteristics of satellite remote sensing Chl a and sea surface temperature(SST),which had some links with sea ice melting and El Ni?o/La Ni?a events.We found that the start time of bloom advanced,lagged or synchronized with the changes of the SST,and we also found the occurrence time of phytoplankton bloom corresponded with the sea ice melting inner bay.To some extent,this study will help us understand the relationships between ENSO events and the phytoplankton bloom in the Southern Ocean. | ZHANG HaiSheng HAN ZhengBing ZHAO Jun YU PeiSong HU ChuanYu SUN WeiPing Yang Dan ZHU GenHai LU Bing Hans-UIrich PETER Walter VETTER | 2014 | Science China Earth Sciences2014，57，12： | 1 |
| 17 | Adaptive Fuzzy Tracking Control for the Chaotic Permanent Magnet Synchronous Motor Drive System Via Backstepping显示文摘 | Yu Jinpeng Chen Bing Yu Haisheng | 2011 | Nonlinear Analysis: Real World Applications2011，12，1： | 1 |
| 18 | Port-Hamiltonian System Modeling and Position Tracking Control of PMSM Based on Maximum Output Power Principle显示文摘 | Yu Haisheng Yu Jinpeng Liu Xudong | 2012 | ICIC Express Letters2012，6，2： | 1 |
| 19 | Adaptive Fuzzy Tracking Control for the Chaotic Permanent Magnet Synchronous Motor Drive System Via Backstepping显示文摘 | Yu Jinpeng Chen Bing Yu Haisheng | 2011 | Nonlinear Analysis: Real World Applications2011，12，1： | 1 |
| 20 | Leaders in multi-agent controllability under consensus algorithm and tree topology显示文摘 | Zhijian Ji Hai Lin Haisheng Yu | 2012 | Systems & Control Letters2012，，9： | 1 |
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