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| 1 | Transformation of alkali and alkaline-earth metals during coal oxy-fuel combustion in the presence of SO_2 and H_2O显示文摘The occurrence modes of alkali and alkaline-earth metals(AAEMs) in coal relate to their release behavior and ash formation during combustion. To better understand the transformation of AAEMs,the release behavior of water-soluble,HCl-soluble,HCl-insoluble AAEMs during Shenmu coal(SM coal) oxy-fuel combustion in the presence of SO2 and H2O in a drop-tube reactor was investigated through serial dissolution using H2O and HCl solutions. The results show that the release rates of AAEMs increase with an increase in temperature under the three atmospheres studied. The high release rates of Mg and Ca from SM coal are dependent on the high content of soluble Mg and Ca in SM coal. SO2 inhibits the release rates of AAEMs,while H2O promotes them. The effects of SO2 and H2O on the Na and K species are more evident than those on Mg and Ca species. All three types of AAEMs in coal can volatilize in the gas phase during coal combustion. The W-type AAEMs release excessively,whereas the release rates of I-type AAEMs are relatively lower. Different types of AAEM may interconvert through different pathways under certain conditions. Both SO2 and H2O promote the transformation reactions. The effect of SO2 was related to sulfate formation and the promotion by H2O occurs because of a decrease in the melting point of the solid as well as the reaction of H2O. | Liying Wang Haixin Mao Zengshuang Wang Jian-Ying Lin Meijun Wang Liping Chang | 2015 | Journal of Energy Chemistry2015，24，4： | 5 |
| 2 | Large Room-Temperature Magnetoresistance in van der Waals Ferromagnet/Semiconductor Junctions显示文摘A magnetic tunnel junction(MTJ)is the core component in memory technologies,such as the magnetic random-access memory,magnetic sensors and programmable logic devices.In particular,MTJs based on twodimensional van der Waals(vd W)heterostructures offer unprecedented opportunities for low power consumption and miniaturization of spintronic devices.However,their operation at room temperature remains a challenge.Here,we report a large tunnel magnetoresistance(TMR)of up to 85%at room temperature(T=300 K)in vdW MTJs based on a thin(<10 nm)semiconductor spacer WSe_(2)layer embedded between two Fe_(3)GaTe_(2e)lectrodes with intrinsic above-room-temperature ferromagnetism.The TMR in the MTJ increases with decreasing temperature up to 164%at T=10 K.The demonstration of TMR in ultra-thin MTJs at room temperature opens a realistic and promising route for next-generation spintronic applications beyond the current state of the art. | Wenkai Zhu Shihong Xie Hailong Lin Gaojie Zhang Hao Wu Tiangui Hu Ziao Wang Xiaomin Zhang Jiahan Xu Yujing Wang Yuanhui Zheng Faguang Yan Jing Zhang Lixia Zhao Amalia Patanè Jia Zhang Haixin Chang Kaiyou Wang | 2022 | Chinese Physics Letters2022，39，12： | 2 |
| 3 | Electrochemical DNA biosensor based on conducting polyaniline nanotube ar?ray显示文摘 | Chang Haixin Yuan Ying Shi Nanlin et a1 | 2007 | Anal Chem2007，79，： | 1 |
| 4 | Upregulated expression of ubiquitin-conjugating enzyme E2Q1 (UBE2Q1) is associated with enhanced cell proliferation and poor prognosis in human hapatocellular carcinoma显示文摘 | Renan Chang Lixian Wei Yuhua Lu Xiaopeng Cui Cuihua Lu Luoliang Liu Dawei Jiang YiCheng Xiong Gang Wang Chunhua Wan Haixin Qian | 2015 | Journal of Molecular Histology2015，，1： | 1 |
| 5 | Quantum dots sensitized graphene: In situ growth and application in photoelectrochemical cells显示文摘 | Haixin Chang Xiaojun Lv Hao Zhang Jinghong Li | 2010 | Electrochemistry Communications2010，，3： | 1 |
| 6 | Kinematic analysis of a new nested inner-outer ring mechanism显示文摘 | CHANG Fuqing JIA Haixin ZHANG Dayu | 2012 | ICIC Express Letters2012，3，6： | 1 |
| 7 | Kinematic analysis of a new nested inner-outer ring mechanism 显示文摘 | Chang Fuqing Jia Haixin Zhang Dayu | 2012 | ICIC Express Letters2012，3，6： | 1 |
| 8 | Kinematic analysis of a new nested inner-outer ring mechanism显示文摘 | CHANG Fuqing JIA Haixin ZHANG Dayue | 2012 | ICIC Express Letters Part B: Applications2012，3，6： | 1 |
| 9 | Endocrine Regulation of Male Fertility by the Skeleton显示文摘 | Franck Oury Grzegorz Sumara Olga Sumara Mathieu Ferron Haixin Chang Charles E. Smith Louis Hermo Susan Suarez Bryan L. Roth Patricia Ducy Gerard Karsenty | 2011 | Cell2011，，5： | 1 |
| 10 | Facile synthesis of wide - bandgap fluorinated graphene semiconductors显示文摘 | Haixin Chang Jinsheng Cheng Xuqing Liu | 2011 | Chemistry - A European Journal2011，17，32： | 1 |
| 11 | A transparent, flexible, low-temperature, and solution-processible graphene composite electrode显示文摘 | Chang Haixin Wang Guangfeng | 2010 | Adv Funct Mater2010，20，： | 1 |
| 12 | Research on Wind Power Prediction Modeling Based on Adaptive Feature Entropy Fuzzy Clustering显示文摘Wind farm power prediction is proposed based on adaptive feature weight entropy fuzzy clustering algorithm.According to the fuzzy clustering method,a large number of historical data of a wind farm in Inner Mongolia are analyzed and classified.Model of adaptive entropy weight for clustering is built.Wind power prediction model based on adaptive entropy fuzzy clustering feature weights is built.Simulation results show that the proposed method could distinguish the abnormal data and forecast more accurately and compute fastly. | HUANG Haixin KONG Chang | 2014 | 沈阳理工大学学报2014，33，4： | 0 |
| 13 | Rapid Microwave Assisted Synthesis and Antiproliferative Evaluation of Novel Steroidal Thiazole Derivatives显示文摘Three series of novel steroidal thiazole derivatives were synthesized by microwave assisted one-potreaction from pregnenolone, testosterone and estrone, respectively. Their structures were characterized by IR, NMRand HRMS, and the antiproliferative activities of all the synthesized compounds against human cervical carcinoma(HeLa), human liver carcinoma(HepG2), human lung carcinoma(A549), nasopharyngeal carcinoma(CNE2) andnormal kidney epithelial cells(HEK293T) were screened. Among the compounds, 1-estron-17'-ylidene-2-[4'-(p-bromophenyl)-2'-thiazol]hydrazone(12) displayed distinct antiproliferative activity against all the tested cancercell lines and was almost inactive to normal kidney epithelial cells. | HUANG Yanmin ZHAO Dandan LIU Chang GAN Chunfang ZHAN Junyan LIN Qifu SHI Haixin CUI Jianguo | 2017 | Chemical Research in Chinese Universities2017，33，2： | 0 |
| 14 | CPAL, as a New Mediator of Cardiomyocyte Metabolic Alterations and Pyroptosis, Regulates Myocardial Infarction Injury in Mice显示文摘Myocardial infarction (MI), the most serious of the ischemic heart diseases, is accompanied by myocardial metabolic disorders and the loss of cardiomyocytes. Increasing evidence has shown that long noncoding RNAs (lncRNAs) are involved in various pathological conditions such as cancer and cardiovascular diseases (CVDs), and are emerging as a novel biomarker for these disorders. This study aims to investigate the regulatory role and mechanisms of lncRNAs in myocardial remodeling in the setting of MI. We find that post-infarcted hearts exhibit a reduction of adenosine triphosphate (ATP) and an alteration of the glucose and lipid metabolism genes cluster of differentiation 36 (CD36), hexokinase 1 (HK1), and clucose transporter 4 (GLUT4), accompanied by cardiomyocyte pyroptosis. We then identify a previously unknown conserved lncRNA, AK009126 (cardiomyocyte pyroptosis-associated lncRNA, CPAL), which is remarkably upregulated in the myocardial border zone of MI mice. Importantly, the adeno-associated virus 9 (AAV9)-mediated silencing of endogenous CPAL by its short hairpin RNA (shRNA) partially abrogates myocardial metabolic alterations and cardiomyocyte pyroptosis during MI in mice. Mechanistically, CPAL is shown to bind directly to nuclear factor kappa B (NFκB) and to act as an activator of NFκB to induce NFκB phosphorylation in cardiomyocytes. We also find that CPAL upregulates caspase-1 expression at the transcriptional level and consequently promotes the release of interleukin (IL)-18 and IL-1β from cardiomyocytes. Collectively, our findings reveal the conserved lncRNA CPAL as a new regulator of cardiac metabolic abnormalities and cardiomyocyte pyroptosis in the setting of MI and suggest CPAL as a new therapeutic target to protect cardiomyocytes against ischemic injury in infarcted hearts. | Jiamin Li Hongru Xue Ning Xu Liling Gong Ming Li Sijia Li Di Huang Qingwei Zhang Pengyu Li Qingsui Li Hang Yu Yining Liu Yadong Xue Haixin Chen Jiali Liu Wanyu Zhang Mingbin Liu Siyu Chang Xianzhi Lang Xingmiao Zhao Weijie Du Benzhi Cai Ning Wang Baofeng Yang | 2023 | Engineering2023，，1： | 0 |
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