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1Isotopic Geochemistry of Cadmium:A Review显示文摘Cadmium(Cd) is a scarce, but not an extremely rare element in the Earth's crust(crustal average: 0.2 ppm Cd). Geochemically, Cd exhibits thiophile, lithophile, and volatile behavior in different geologic processes. Biologically, it is a nutrient-like element that is closely related to P and Zn and is toxic element to organisms. Presently, Cd isotopes have been successfully utilized to trace Cd sources and nutrient cycling in marine systems in addition to unearthing other geochemical processes. Using published studies and our recent work, this survey summarizes the chemical preparation and mass spectrometry of Cd isotopes. It also reviews Cd isotopic compositions and fractionation mechanisms in nature as well as experiments.ZHU Chuanwei WEN Hanjie ZHANG Yuxu LIU Yizhang WEI Rongfei 2015Acta Geologica Sinica(English Edition)2015,89,6:3
2Simulation on the spatio-temporal distribution and emission flux of dust aerosol over East Asia in 2000-2009显示文摘A regional climate model (RegCM3), coupled with an online dust module, is used to simulate the spatio-temporal distribution and emission flux of dust aerosol (smaller than 20 μm in diameter) over East Asia in the period from 2000 to 2009. The model performance is firstly evaluated against available observations. Simulation results show that the model can capture the characteristics of spatio-temporal distribution of dust aerosol very well over East Asia. There always exist two extremes of dust aerosol optical depth (AOD) and column burden (CB), one is in the Taklimakan Desert of Xinjiang Uygur Autonomous Region, China, and the other is in the Badain Jaran Desert of Inner Mongolian Autonomous Region, China. The maximum value of CB appears in spring, secondary maximum in winter and minimum in autumn. To the east of 110°E, dust is transported eastward from a maximum center at a height of 700 hPa over the East Asian continent. Dust emission sources are mainly located in the Taklimakan Desert, Badain Jaran Desert, North Qinghai-Tibetan Plateau and Southwest Mongolia. There is also an obvious seasonal variation of dust emission flux (EF). Annual mean dust EF is 1,015.34 mg/(m 2 ·d), of which 62.4% and 2.3% are re-deposited onto the East Asian continent through a dry and wet deposition process, respectively, and the remaining 35.3% is injected into the atmosphere or subject to long-range transport.XingTao Su HanJie Wang HengRui Tao LieShuang Liu HongFeng Zhang 2013Research in Cold and Arid Regions2013,5,2:3
3Late Mesozoic rifting and its deep dynamic mechanisms in the central Sulu orogenic belt: Records from Lingshan Island显示文摘The Lingshan Island scientific drill confirms that two episodes(Laiyang period and Qingshan period) of rifting developed in the central Sulu orogenic belt(SOB) in Late Mesozoic. With a set of methods including fieldwork, drilling, core logging, zircon U-Pb dating and whole rock geochemistry applied, the age, the depositional sequence and the deep dynamic mechanisms of rift evolution were unraveled. The stratigraphic sequence of the Laiyang-Qingshan Groups on Lingshan Island was composed of two different rifting sequences:(1) Laiyang Group(147–125 Ma), which consists of deep-water gravity flow deposits with interlayers of intermediate volcanic rocks;and(2) Lower Qingshan Group(125–119 Ma), which unconformably overlies the former sequence and contains subaerial volcanic deposits and terrestrial deposits. The tectonic environment changed during the evolution of these two episodes of rifting: the rift was in a NNW-SSE extensional environment in the Laiyang period and showed the typical passive rifting character that “lithospheric extension and rifting preceded volcanism”. The passive rifting period was ended by a short WNW-ESE compression at about 125 Ma. After that, the tectonic environment transferred to a strong NW-SE extensional environment and the rifting evolved into a volcanic arc basin in the Qingshan period. The igneous rocks are shoshonitic to high-K calc-alkaline trachyandesites to trachytes with a few intercalated lamprophyres and a rhyolite.The geochemical characteristics of the igneous rocks indicate that they are mantle-derived melts with a metasomatized mantle source and/or crustal contamination. In addition, an increased thinning of the lithosphere happened during the rifting episodes.The low-angle subduction of the Paleo-Pacific plate in the Jurassic weakened the thickened SOB lithospheric mantle. The rollback of the subducting plate started in late Jurassic to early Cretaceous, and the SOB lithospheric mantle was delaminated synchronously because of the gravity collapse. Thus, this caused passive rifting in the Laiyang period. Thereafter, the rollback and trench retreat of the high-angle subducting Paleo-Pacific plate would have achieved its climax, resulting in the strong regional extension. Passive rifting was ended by the crustal uplift caused by asthenospheric upwelling beneath the rift. The lower crust was heated by the upwelling asthenosphere and partially melted to form felsic melts, which were emplaced upwards and erupted explosively. The rift evolved into a volcanic arc basin in the Qingshan period and showed some characteristics of active rifting. Above all, a passive rifting in the Laiyang period and a volcanic arc basin in the Qingshan period developed successively in the Lingshan Island area(the central SOB). This records the transfer of the study area from the Paleo-Tethys tectonic domain to the circum-Pacific tectonic domain. The delamination of SOB lithospheric mantle and the upwelling of asthenospheric material were the deep dynamic mechanisms driving the development and evolution of two rift episodes. Additionally, the rift development was controlled remotely by the subduction of the Paleo-Pacific plate.Tengfei ZHOU Yaoqi ZHOU Nina SФAGER Paul Martin HOLM Zhenkai ZHANG Jun WANG Zhao LIANG Hongyu MU Yanjun CHENG Feifei LIU Miao WANG Yue ZHANG Hui ZHANG Yangjian GU Shihui DONG Hanjie ZHAO Manjie LI Yang CHEN Yanzi LIU 2022Science China Earth Sciences2022,65,9:3
4Evidence for charge and spin density waves in single crystals of La_(3)Ni_(2)O_(7) and La_(3)Ni_(2)O_(6)显示文摘Charge and spin orders are intimately related to superconductivity in copper oxide superconductors.Elucidation of the competing orders in various nickel oxide compounds is crucial,given the fact that superconductivity has been discovered in Nd_(0.8)Sr_(0.2)NiO_(2)films.Herein,we report structural,electronic transport,magnetic,and thermodynamic characterizations of single crystals of La_(3)Ni_(2)O_(7)and La_(3)Ni_(2)O_(6).La_(3)Ni_(2)O_(7)is metallic with mixed Ni^(2+)and Ni^(3+)valent states.Resistivity measurements yield two transition-like kinks at~110 and 153 K.The kink at 153 K is further revealed from magnetization and specific heat measurements,indicative of the formation of charge and spin density waves.La_(3)Ni_(2)O_(6)single crystals obtained from the topochemical reduction of La_(3)Ni_(2)O_(7)are insulating and show an anomaly at~176 K on magnetic susceptibility.The transition-like behaviors of La_(3)Ni_(2)O_(7)and La_(3)Ni_(2)O_(6)are analogous to those observed in La_(4)Ni_(3)O_(10) and La_(4)Ni_(3)O_(8),suggesting that charge and spin density waves are a common feature in the ternary La-Ni-O system with mixed-valent states of nickel.Zengjia Liu Hualei Sun Mengwu Huo Xiaoyan Ma Yi Ji Enkui Yi Lisi Li Hui Liu Jia Yu Ziyou Zhang Zhiqiang Chen Feixiang Liang Hongliang Dong Hanjie Guo Dingyong Zhong Bing Shen Shiliang Li Meng Wang 2023Science China(Physics,Mechanics & Astronomy)2023,66,1:2
5FUNCTIONS OF TEACHER′S REPETITION IN CLASSROOM INTERACTION显示文摘Liu Hanjie(English Department of Henan Finance and Econmic Institure,Zhengzhou,450000) 1998天中学刊1998,13,S1:2
6A micro-nano optogenetic system based on probiotics for in situ host metabolism regulation显示文摘Genetically engineered bacteria have aroused attention as micro-nano drug delivery systems in situ.However,conventional designs of engineered bacteria usually function constantly or autonomously,which might be non-specific or imprecise.Therefore,designing and optimizing in situ control strategy are important methodological progress for therapeutic researches of intestinal engineered bacteria.Here,a micro-nano optogenetic system based on probiotic was developed combining microelectronics,nanotechnology,and synthetic biology to achieve in situ controllable drug delivery.Firstly,optogenetic engineered Lactococcus lactis was orally administrated in the intestinal tract.A wearable optical device was designed to control optical signals remotely.Then,L.lactis could be customized to secrete peptides according to optical signals.As an example,optogenetic L.lactis system can be constructed to secrete glucagon-like peptide-1(GLP-1)under the control of the wearable optical device to regulate metabolism.To improve the half-life of GLP-1 in vivo,Fc-domain fused GLP-1 was optimally used.Using this strategy,blood glucose,weight,and other features were well controlled in rats and mice models.Furthermore,upconversion microcapsules were introduced to increase the excitation wavelength of the optogenetic system for better penetrability.This strategy has biomedical potential to expand the toolbox for intestinal engineered bacteria.Xinyu Zhang Ning Ma Wei Ling Gaoju Pang Tao Sun Jing Liu Huizhuo Pan Meihui Cui Chunli Han Chun Yang Jin Chang Xian Huang Hanjie Wang 2023Nano Research2023,16,2:2
7Single-Cell Exome Sequencing Reveals Single-Nucleotide Mutation Characteristics of a Kidney Tumor显示文摘Xun Xu Yong Hou Xuyang Yin Li Bao Aifa Tang Luting Song Fuqiang Li Shirley Tsang Kui Wu Hanjie Wu Weiming He Liang Zeng Manjie Xing Renhua Wu Hui Jiang Xiao Liu Dandan Cao Guangwu Guo Xueda Hu Yaoting Gui Zesong Li Wenyue Xie Xiaojuan Sun Min Shi Zhiming 2012Cell2012,,5:1
8The evolution of the Kuroshio Current over the last 5 million years since the Pliocene: Evidence from planktonic foraminiferal faunas显示文摘Meridional heat transport of the western Pacific boundary current(the Kuroshio Current)is one of the key factors in global climate change.This current is important because it controls the temperature gradient between low latitudes and the North Pacific and so significantly influences mid-latitude atmosphere-ocean interactions.Here we reconstruct changes in hydrological conditions within the mid-latitude mainstream of the Kuroshio Current based on faunal analysis of planktonic foraminifera in core DSDP 296 from the Northwest Pacific Ocean.This approach enabled us to deduce evolutionary processes within the Kuroshio Current since the Pliocene.A total of 57 species in the coarser section(>150μm)were identified;results indicate that planktonic foraminiferal faunal evolution has mainly been characterized by three major stages,the first of which comprised mixed-layer warm-water species of Globigerinoides ruber which first appeared between 3.5 and 2.7 Ma and then gradually increased in content.Percentages of another warm-water species of G.conglobatus also gradually increased in number over this interval.Variations in warm-water species indicate a gradual rise in sea surface temperature(SST)and imply initiation of Kuroshio Current impact on the Northwest Pacific Ocean since at least 3.5 Ma.Secondly,over the period between 2.7 and 2.0 Ma,thermocline species of Globigerina calida,Neogloboquadrina humersa,Neogloboquadrina dutertrei,and Pulleniatina obliquiloculata started to appear in the section.This fauna was dominated by G.ruber as well as increasing G.conglobatus contents.These features imply a further rise in SST and its gradually enhanced influence on thermocline water,suggesting strengthening of the Kuroshio Current since 2.7 Ma.Thirdly,between 2.0 Ma and present,increasing contents of thermocline species(i.e.,G.calida,N.dutertrei and P.obliquiloculata)indicate a gradual rise in seawater temperature at this depth and also imply more intensive Kuroshio Current during this period.On the basis of comparative records from cores ODP 806 and DSDP292 from the low latitude Western Pacific,we propose that initiation of the impact of the Kuroshio Current in the Northwest Pacific and it subsequent stepwise intensifications since 3.5 Ma can be closely related to the closure and restriction of the Indonesian and Central American seaways as well as variations in the Western Pacific Warm Pool(WPWP)and equatorial Pacific region.Jia WANG Fengming CHANG Tiegang LI Hanjie SUN Yikun CUI Tianhao LIU 2020Science China Earth Sciences2020,63,11:1
9Selective separation of biobutanol from acetone–butanol–ethanol fermentation broth by means of sorption methodology based on a novel macroporous resin显示文摘Xiaoqing Lin Jinglan Wu Xiaohong Jin Jiansheng Fan Renjie Li Qingshi Wen Wenbin Qian Dong Liu Xiaochun Chen Yong Chen Jingjing Xie Jianxin Bai Hanjie Ying 2012Biotechnol Progress2012,,4:1
10Combined invariants to blur and rotation using Zernike moment descriptors显示文摘Hongqing Zhu Min Liu Hanjie Ji Yu Li 2010Pattern Analysis and Applications2010,,3:1
11Novel higher order mass matrices for isogeometric structural vibration analysis 显示文摘Wang Dongdong Liu Wei Zhang Hanjie 2013Computer Methods in Applied Mechanics and Engineering2013,260,1234:1
12Geochemistry and mineralogy of REY-rich mud in the eastern Indian Ocean显示文摘Kazutaka Yasukawa Hanjie Liu Koichiro Fujinaga Shiki Machida Satoru Haraguchi Teruaki Ishii Kentaro Nakamura Yasuhiro Kato 2014Journal of Asian Earth Sciences2014,,:1
13Application of Solar Power in Less Developed Regions Under the Background of Low-Carbon Economy显示文摘Development of a low-carbon economy and reduction of carbon emissions is the trend of future global socio-economic change,and the only way to mitigate climate change under the framework of sustainable development.Based on the concept of a low-carbon economy,the author attempts to f ind a way for underdeveloped regions,which can satisfy their own development without increasing the pressure on the local environment.Taking Guizhou Suiyang as an example,the solar power designed in the land application provides a low-carbon case study of underdeveloped areas to solve the issue of power supply.Lu Sibin Liu Hanjie 2014Electricity2014,25,4:0
14Effects of nitrogen fertilizer application on saline-alkali land cotton in China quantified using meta-analysis and regression analysis显示文摘Nitrogen fertilizer application is an important means to promote cotton production in saline-alkali land.A metaanalysis and regression analysis of 49 peer-reviewed studies were conducted using yield data(373 data points),dry matter accumulation(114 data points),and water use efficiency(157 data points)to quantify the effect of nitrogen fertilizer on the yield,dry matter accumulation,and water use efficiency of cotton in saline-alkali land in China for different planting management practices and different growing environments.The results showed that the nitrogen application significantly improved the yield,dry matter accumulation,and water use efficiency by 34.11%,36.27%,and 33.87%,respectively,compared with no nitrogen application.The largest improvements in the yield,dry matter accumulation,and water use efficiency occurred in areas where saline-alkali land had been improved for many years,in Eastern China,South Central China,and Northwest China(areas with annual average precipitation≤200 mm or>800 mm,and annual average evaporation≤800 mm or>2400 mm),in areas with trickle irrigation,and fields with a planting density of 100000 to 250000 plants/hm2.Cotton exhibited the optimal response to nitrogen application at a rate of 300-375 kg/hm2,a basal application ratio of 20%-40%,and top-dressing in the cotton bud,flowering boll,and full boll stages.The effect of nitrogen application increased as the salinity increased.A suitable nitrogen application rate,top-dressing ratio,and top-dressing period are crucial for increasing cotton production in saline-alkali land,although environmental differences and planting measures have to be considered.This study provided information on the correct application of nitrogen fertilizer to maximize its benefits and suggests controlling nitrogen fertilizer inputs in agriculture to protect the soil environment and ensure sustainable agricultural development.Changkun Yang Hongguang Liu Ping Gong Pengfei Li Xiang Qiao Zhijie Li Hua Jin Qian Zhang Hanji Xia 2023International Journal of Agricultural and Biological Engineering2023,16,4:0
15An ultra-accurate dynamic isogeometric analysis with higher order mass formulation显示文摘An ultra-accurate isogeometric dynamic analysis is presented.The key ingredient of the proposed methodology is the development of isogeometric higher order mass matrix.A new one-step method is proposed for the construction of higher order mass matrix.In this approach,an adjustable mass matrix is formulated through introducing a set of mass parameters into the consistent mass matrix under the element mass conservation condition.Then the semi-discrete frequency derived from the free vibration equation with the adjustable mass matrix is served as a measure to optimize the mass parameters.In 1D analysis,it turns out that the present one-step method can perfectly recover the existing reduced bandwidth mass matrix and the higher order mass matrix by choosing different mass parameters.However,the employment of the proposed one-step method to the2D membrane problem yields a remarkable gain of solution accuracy compared with the higher order mass matrix generated by the original two-step method.Subsequently a full-discrete isogeometric transient analysis algorithm is presented by using the Newmark time integration scheme and the higher order mass matrix.The full-discrete frequency is derived to assess the accuracy of space-time discretization.Finally a set of numerical examples are presented to evaluate the accuracy of the proposed method,which show that very favorable solution accuracy is achieved by the present dynamic isogeometric analysis with higher order mass formulation compared with that obtained from the standard consistent mass approach.WANG DongDong LI XiWei LIU Wei ZHANG HanJie 2014Science China(Technological Sciences)2014,57,7:0
16Complex network approach for the evaluation of asphalt pavement design and construction: a longitudinal study显示文摘The assessment of asphalt pavement structures with diversified designs and constructions has been a critical challenge due to the practical limitations in testing and methodology. Here, we propose a complex network approach to the evaluation of longitudinal asphalt pavement performances in the Research Institute of Highway Ministry of Transport track(RIOHTrack). We add to the growing field in which network approaches are employed and indicate the profound application in understanding pavement structures.Specifically, similar and disparate pavement performances are revealed regardless of their predefined design and construction categories. Evidence shows that short-term pavement performance depends on the strength of the subbase structure, whereas long-term performance relies on the thickness of the asphalt layer. In addition, our results indicate that recycling materials could be an important substitute for reducing the thickness of asphalt concrete and maintaining a healthy service life.Hanjie LIU Jinde CAO Wei HUANG Xinli SHI Xudong WANG 2022Science China(Information Sciences)2022,65,7:0
17Identification of a sensor histidine kinase (BfcK) controlling biofilm formation in Clostridium acetobutylicum显示文摘Clostridium acetobutylicum has been extensively exploited to produce biofuels and solvents and its biofilm could dramatically improve the productivities.However,genetic control of C.acetobutylicum biofilm has not been dissected so far.Here,to identify potential genes controlling C.acetobutylicum biofilm formation,over 40 gene candidates associated with extracellular matrix,cell surface,cell signaling or gene transcription,were tried to be disrupted to examine their individual impact.A total of 25 disruptants were finally obtained over years of attempts,for which biofilm and relevant phenotypes were characterized.Most of these disruptants formed robust biofilm still,or suffered both growth and biofilm defect.Only a strain with a disrupted histidine kinase gene(CA_C2730,designated bfcK in this study)abolished biofilm formation without impairing cell growth or solvent production.Further analysis revealed that bfcK could control flagellar biogenesis and cell motility at protein levels.The bfcK also appeared to repress the phosphorylation of a serine/threonine protein kinase(encoded by CA_C0404)that might negatively regulate biofilm formation.Based on these findings,possible bfcK-mediated mechanisms for biofilm formation were proposed.This is a big step toward understanding the biofilm formation in C.acetobutylicum and will help further engineering of its biofilm-based industrial processes.Dong Liu Shikai Ge Zhenyu Wang Mengting Li Wei Zhuang Pengpeng Yang Yong Chen Hanjie Ying 2022Chinese Journal of Chemical Engineering2022,35,6:0
18Metabolomics variation profiling of vaginal discharge identifies potential targets for cervical cancer early warning显示文摘Cervical cancer(CC)continues to be the second leading cause of cancer death in women aged 20 to 39[1].Recent research has shown that the cervical microbiota differs in different stages of cervical carcinogenesis[2].It has been reported that the gut microbiota is linked to host metabolism,which influences the progression of the disease[3].The role of cervicovaginal flora in affecting host metabolism,thereby causing the progression of cervical cancer,requires further research.In this direction,metabolomics has been implemented to detect small molecular differential metabolites in cancer progression.Metabolomics is the study of the thousands of low-molecular-weight molecules found in biological fluids and tissues of different individuals,whether normal or afflicted with disease,and it reflects reasonable changes in biological functions.Hanjie Xu Min Liu Yuexiao Song Lou Liu Feng Xu Jiale Chen Huiying Zhan Ye Zhang Yu Chen Mudan Lu Daozhen Chen 2022Acta Biochimica et Biophysica Sinica2022,54,10:0
19Microbiome-metabolome analysis reveals cervical lesion alterations显示文摘Cervical cancer(CC)continues to be one of the most common cancers among females worldwide.It takes a few years or even decades for CC to arise in a minority of women with cervical precancers.An increasing corpus of studies today indicates that local microecology and carcinogenesis are intimately related.To investigate the changes in cericovaginal microecology with the development of cervical cancer,we performed 16S rDNA sequencing and metabolomic analysis in cericovaginal fluid from 10 LSIL patients,10 HSIL patients,10 CC patients and 10 healthy controls to reveal the differential flora and metabolites during cervical carcinogenesis.Carcinogenesis is associated with alterations in microbiome diversity,individual taxa,and functions with notable changes in Lactobacillus,Prevotella and Aquabacterium,as well as in cervicovaginal metabolites that correlate with cervicovaginal microbial patterns.Increased bacterial diversity and a decline in the relative abundance of Lactobacillus,the dominant species in the cericovaginal flora,are observed when cervical lesions advance.According to KEGG pathway enrichment analysis,lipids and organic acids change as cervical cancer progresses,and the phenylalanine,tyrosine,and tryptophan biosynthesis pathway is essential for the development of cervical cancer.Our results reveal that microbic and metabolomic profiling is capable of distinguishing CC from precancer and highlights potential biomarkers for the early detection of cervical dysplasia.These differential microorganisms and metabolites are expected to become a potential tool to assist in the diagnosis of cervical cancer.Hanjie Xu Lou Liu Feng Xu Min Liu Yuexiao Song Jiale Chen Huiying Zhan Ye Zhang Dexiang Xu Yu Chen Mudan Lu Daozhen Chen 2022Acta Biochimica et Biophysica Sinica2022,54,10:0
20RING finger 138 deregulation distorts NF-κB signaling and facilities colitis switch to aggressive malignancy显示文摘Prolonged activation of nuclear factor(NF)-кB signaling significantly contributes to the development of colorectal cancer(CRC).New therapeutic opportunities are emerging from targeting this distorted cell signaling transduction.Here,we discovered the critical role of RING finger 138(RNF138)in CRC tumorigenesis through regulating the NF-кB signaling,which is independent of its Ubiquitin-E3 ligase activity involved in DNA damage response.RNF138^(−/−) mice were hyper-susceptible to the switch from colitis to aggressive malignancy,which coincided with sustained aberrant NF-кB signaling in the colonic cells.Furthermore,RNF138 suppresses the activation of NF-кB signaling pathway through preventing the translocation of NIK and IKK-Beta Binding Protein(NIBP)to the cytoplasm,which requires the ubiquitin interaction motif(UIM)domain.More importantly,we uncovered a significant correlation between poor prognosis and the downregulation of RNF138 associated with reinforced NF-кB signaling in clinical settings,raising the possibility of RNF138 dysregulation as an indicator for the therapeutic intervention targeting NF-кB signaling.Using the xenograft models built upon either RNF138-dificient CRC cells or the cells derived from the RNF138-dysregulated CRC patients,we demonstrated that the inhibition of NF-кB signaling effectively hampered tumor growth.Overall,our work defined the pathogenic role of aberrant NF-кB signaling due to RNF138 downregulation in the cascade events from the colitis switch to colonic neoplastic transformation and progression,and also highlights the possibility of targeting the NF-кB signaling in treating specific subtypes of CRC indicated by RNF138-ablation.Yalan Lu Rong Huang Jianming Ying Xingchen Li Tao Jiao Lei Guo Haitao Zhou Han Wang Amannisa Tuersuntuoheti Jianmei Liu Qichen Chen Yanhong Wang Luying Su Changyuan Guo Fu Xu Ziyi Wang Yan Lu Kai Li Junbo Liang Zhen Huang Xiao Chen Jinjie Yao Hanjie Hu Xiaowen Cheng Yufeng Wan Xinyan Chen Ning Zhang Shiying Miao Jianqiang Cai Linfang Wang Changzheng Liu Wei Song Hong Zhao 2022Signal Transduction and Targeted Therapy2022,7,7:0
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