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12篇 您的检索式:作者名="Hanzhang Chen"
    题名 作者 年代 出处 被引量
1Suppression of m6A reader Ythdf2 promotes hematopoietic stem cell expansion显示文摘Zhenrui Li Pengxu Qian Wanqing Shao Hailing Shi Xi C. He Madelaine Gogol Zulin Yu Yongfu Wang Meijie Qi Yunfei Zhu John M. Perry Kai Zhang Fang Tao Kun Zhou Deqing Hu Yingli Han Chongbei Zhao Richard Alexander Hanzhang Xu Shiyuan Chen Allison Peak Kathyrn Hall Michael Peterson Anoja Perera Jeffrey S. Haug Tari Parmely Hua Li Bin Shen Julia Zeitlinger Chuan He Linheng Li 2018Cell Research2018,28,9:18
2Nonintubated uniportal video-assisted thoracoscopic surgery for primary spontaneous pneumothorax显示文摘Objective:The objective of the current study was to evaluate the feasibility and safety of nonintubated uniportal video-assisted thoracoscopic surgery(VATS) for the management of primary spontaneous pneumothorax(PSP).Methods:From November 2011 to June 2013,32 consecutive patients with PSP were treated by nonintubated uniportal thoracoscopic bullectomy using epidural anaesthesia and sedation without endotracheal intubation.An incision 2 cm in length was made at the 6^(th) intercostal space in the median axillary line.The pleural space was entered by blunt dissection for placement of a soft incision protector.Instruments were then inserted through the incision protector to perform thoracoscopic bullectomy.Data were collected within a minimum follow-up period of 10 months.Results:The average time of surgery was 49.0 min(range,33-65 min).No complications were recorded.The postoperative feeding time was 6 h.The mean postoperative chest tube drainage and hospital stay were19.3 h and 41.6 h,respectively.The postoperative pain was mild for 30 patients(93.75%) and moderate for two patients(6.25%).No recurrences of pneumothorax were observed at follow-up.Conclusions:The initial results indicated that nonintubated uniportal video-assisted thoracoscopic operations are not only technically feasible,but may also be a safe and less invasive alternative for select patients in the management of PSP.This is the first report to include the use of a nonintubated uniportal technique in VATS for such a large number of PSP cases.Further work and development of instruments are needed to define the applications and advantages of this technique.Shuben Li Fei Cui Jun Liu Xin Xu Wenlong Shao Weiqiang Yin Hanzhang Chen Jianxing He 2015Chinese Journal of Cancer Research2015,27,2:15
3Safety and feasibility of video-assisted thoracoscopic surgery for stage IIIA lung cancer显示文摘Objective: The current study was prospectively designed to explore the application of video-assisted thoracoscopic surgery(VATS) radical treatment for patients with stage IIIA lung cancer, with the primary endpoints being the safety and feasibility of this operation and the second endpoints being the survival and complications after the surgery.Methods: A total of 51 patients with radiologically or mediastinoscopically confirmed stage IIIA lung cancer underwent VATS radical treatment, during which the standard pulmonary lobectomy and mediastinal lymph node dissection were performed after pre-operative assessment. The operative time, intraoperative blood loss/complications, postoperative recovery, postoperative complications, and lymph node dissection were recorded and analyzed. This study was regarded as successful if the surgical success rate reached 90% or higher.Results: A total of 51 patients with non-small cell lung cancer(NSCLC) were enrolled in this study from March 2009 to February 2010. The median post-operative follow-up duration was 50.5 months. Of these 51 patients, 41(80.4%) had N2 lymph node metastases. All patients underwent the thoracoscopic surgeries, among whom 50(98%) received pulmonary lobectomy and mediastinal lymph node dissection completely under the thoracoscope, 6 had their incisions extended to about 6 cm due to larger tumor sizes, and 1 had his surgery performed using a 12 cm small incision for handling the adhesions between lymph nodes and blood vessels. No patient was converted to conventional open thoracotomy. No perioperative death was noted. One patient received a second surgery on the second post-operative day due to large drainage(>1,000 mL), and the postoperative recovery was satisfactory. Up to 45 patients(88.2%) did not suffer from any perioperative complication, and 6(11.8%) experienced one or more complications.Conclusions: VATS radical treatment is a safe and feasible treatment for stage IIIA lung cancer.Wenlong Shao Jun Liu Wehua Liang Hanzhang Chen Shuben Li Weiqiang Yin Xin Zhang Jianxing He 2014Chinese Journal of Cancer Research2014,26,4:12
4Long-term survival outcomes of video-assisted thoracic surgery for patients with non-small cell lung cancer显示文摘Background: Video-assisted thoracic surgery(VATS) has been shown to be a safe alternative to conventional thoracotomy for patients with non-small cell lung cancer(NSCLC). However, popularization of this relatively novel technique has been slow, partly due to concerns about its long-term outcomes. The present study aimed to evaluate the long-term survival outcomes of patients with NSCLC after VATS, and to determine the significant prognostic factors on overall survival.Methods: Consecutive patients diagnosed with NSCLC referred to one institution for VATS were identified from a central database. Patients were treated by either complete-VATS or assisted-VATS, as described in previous studies. A number of baseline patient characteristics, clinicopathologic data and treatment-related factors were analyzed as potential prognostic factors on overall survival.Results: Between January 2000 and December 2007, 1,139 patients with NSCLC who underwent VATS and fulfilled a set of predetermined inclusion criteria were included for analysis. The median age of the entire group was 60 years, with 791 male patients(69%). The median 5-year overall survival for Stage I, II, III and IV disease according to the recently updated TNM classification system were 72.2%, 47.5%, 29.8% and 28.6%, respectively. Female gender, TNM stage, pT status, and type of resection were found to be significant prognostic factors on multivariate analysis.Conclusions: VATS offers a viable alternative to conventional open thoracotomy for selected patients with clinically resectable NSCLC.Wenlong Shao Xinguo Xiong Hanzhang Chen Jun Liu Weiqiang Yin Shuben Li Xin Xu Xin Zhang Jianxing He 2014Chinese Journal of Cancer Research2014,26,4:5
5Isolation and characterization of emerging subgroup J avian leukosis virus associated with hemangioma in egg-type chickens显示文摘Hanzhang Lai Henan Zhang Zhangyong Ning Ruiai Chen Wenyan Zhang Aijian Qing Chaoan Xin Kangzhen Yu Weisheng Cao Ming Liao 2011Veterinary Microbiology2011,,3:3
6A Trajectory Prediction Based Intelligent Handover Control Method in UAV Cellular Networks显示文摘The airborne base station(ABS) can provide wireless coverage to the ground in unmanned aerial vehicle(UAV) cellular networks.When mobile users move among adjacent ABSs,the measurement information reported by a single mobile user is used to trigger the handover mechanism.This handover mechanism lacks the consideration of movement state of mobile users and the location relationship between mobile users,which may lead to handover misjudgments and even communication interrupts.In this paper,we propose an intelligent handover control method in UAV cellular networks.Firstly,we introduce a deep learning model to predict the user trajectories.This prediction model learns the movement behavior of mobile users from the measurement information and analyzes the positional relations between mobile users such as avoiding collision and accommodating fellow pedestrians.Secondly,we propose a handover decision method,which can calculate the users' corresponding receiving power based on the predicted location and the characteristic of air-to-ground channel,to make handover decisions accurately.Finally,we use realistic data sets with thousands of non-linear trajectories to verify the basic functions and performance of our proposed intelligent handover controlmethod.The simulation results show that the handover success rate of the proposed method is 8% higher than existing methods.Bo Hu Hanzhang Yang Lei Wang Shanzhi Chen 2019China Communications2019,16,1:3
7Video-Assisted Thoracoscopic Surgery (VATS) for Patients with Solitary Fibrous Tumors of the Pleura显示文摘Jun Liu Chengjie Cai Daoyuan Wang Hanzhang Chen Linling Cheng Wenlong Shao Shuben Li Yubao Guan Yingying Gu Jianxing He 2010Journal of Thoracic Oncology2010,,2:2
8Rose Bengal staining in detection of oral precancerous and malignant lesions with colorimetric evaluation: a pilot study 显示文摘Du Gefei Li Chengzhang Chen Hanzhang 2007International Journal of Cancer2007,120,9:1
9Prognostic impact of MMP‐2 and MMP‐9 expression in pathologic stage IA non‐small cell lung cancer 显示文摘Wenlong Shao Wei Wang Xin‐guo Xiong Christopher Cao Tristan D. Yan Guoqin Chen Hanzhang Chen Weiqiang Yin Jun Liu Yingying Gu Mingcong Mo Jianxing He 2011J. Surg. Oncol2011,,:1
10Impacts of thrusting,extensional faulting,and glaciation on cratering records of Pluto’s largest moon Charon:Implications for the evolution of Kuiper belt objects显示文摘A first-order question in the studies of the Solar System is how its outer zone known as the Kuiper belt was created and evolved.Two end-member models, involving coagulation vs. streaming instability, make different predictions-testable by the cratering history of Kuiper Belt Objects(KBOs)-about the cumulative size-frequency distribution(SFD) of the KBOs. Among all of the imaged KBOs, Pluto’s largest icy moon, Charon, appears to preserve the largest size range of seemingly undisturbed craters, their diameters(D) on Charon ranging from < 1 km to > 220 km. Current work shows that Charon’s craters with D < 10-20 km are fewer than those expected by the coagulation mechanism, but whether this is an artifact of post-cratering modification of smaller craters is unknown. We address this issue by conducting systematic photogeological mapping and performing detailed landform analysis using the highest resolution images obtained by the New Horizons spacecraft, which reveal a range of differentiable terrains on Charon. The most important findings of our work include(1) truncation and obliteration of large craters(diameters > 30-40 km) and their crater rim ridges along the eastern edges of several north-trending, eastward-convex, arcuate ranges in Oz Terra of the northern encountered hemisphere,(2) lobate ridges, lobate knob trains, and lobate aprons resembling glacial moraine landforms on Earth,(3) dendritic channel systems containing hanging valleys,and(4) locally striated surfaces defined by parallel ridges, knob trains, and grooves that are > 40-50 km in length. The above observations and the topographic dichotomy of Charon’s encountered hemisphere can be explained by a landscape-evolution model that involves(i)a giant impact that created the Vulcan Planitia basin and the extensional fault zone along its northern rim,(ii) a transient atmosphere capable of driving N2-ice glacial erosion of the water-ice bedrock and transporting water-ice debris to sedimentary basins,(iii) regional glacial erosion and transport of earlier emplaced impact ejecta deposits from the highlands of Oz Terra into the lowland basin of Vulcan Planitia,(iv) syn-glaciation north-trending thrusting, interpreted to have been induced by Charon’s despinning, and(v) the development of a water-ice debris cover layer over subsurface N2 ice below Vulcan Planitia during global deglaciation. The infilling of the Vulcan Planitia could have been accompanied by cryovolcanism. The extensive modification of impact craters means that the size-frequency distributions of Charon’s craters should serve only as a lower bound when used to test formation mechanisms proposed for Kuiper belt objects.HanZhang Chen An Yin 2022Earth and Planetary Physics2022,6,6:0
11A CHARACTERISTIC MIXED FINITE ELEMENT TWO-GRID METHOD FOR COMPRESSIBLE MISCIBLE DISPLACEMENT PROBLEM显示文摘A nonlinear parabolic system is derived to describe compressible miscible displacement in a porous medium.The concentration equation is treated by a mixed finite element method with characteristics(CMFEM)and the pressure equation is treated by a parabolic mixed finite element method(PMFEM).Two-grid algorithm is considered to linearize nonlinear coupled system of two parabolic partial differential equations.Moreover,the L q error estimates are conducted for the pressure,Darcy velocity and concentration variables in the two-grid solutions.Both theoretical analysis and numerical experiments are presented to show that the two-grid algorithm is very effective.Hanzhang Hu Yanping Chen 2022Journal of Computational Mathematics2022,40,5:0
12A case of thymic Langerhans cell histiocytosis with diabetes insipidus as the first presentation显示文摘Langerhans cell histiocytosis(LCH)is an idiopathic group of reactive proliferative diseases linked to aberrant immunity,pathologically characterized by clonal proliferation of Langerhans cells.LCH rarely involves the thymus.We report a case of thymic LCH with diabetes insipidus as the first presentation,without evidence of myasthenia gravis and without evidenced involvement of the skin,liver,spleen,bones,lungs and superficial lymph nodes.This present case may have important clinical implications.In screening for LCH lesions,attention should be attached to rarely involved sites in addition to commonly involved organs.Follow-up and imageological examination are very important to a final diagnosis.Xiaoyan Chen Xiaochun Huang Yuan Qiu Hanzhang Chen Yingyu Fu Xinchun Li 2013Frontiers of Medicine2013,7,1:0
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