|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Numerical analysis of the failure process of soil-rock mixtures through computed tomography and PFC3D models显示文摘 | Yang Ju Huafei Sun Mingxu Xing Xiaofei Wang Jiangtao Zheng | 2018 | International Journal of Coal Science & Technology2018，5，2： | 17 |
| 2 | Construction of chimeric inducible promoters by elicitors of rice fungal blast pathogen and their expression in transgenic rice显示文摘The promoter fragments of wheat GstA1 and potato Gst1 have been amplified by PCR, cloned and fused respectively to the minimal promoter sequence of rice actin gene (Act1)) and its 5’ untranslated leader sequence together with GUS. The constructs with 2 chimeric promoters (WGA and PGA) have been transferred into rice in order to analyze their inducibility patterns in transgenic rice plants. The results show that: WGA and PGA are both inducible by elicitors of Pyricularia oryzae in transgenic rice cells; the intron I of rice Act1 gene is important for the heterogenic expression of monocot and dicot promoter elements in rice; and the Act1 minimal promoter and its 5’untranslated leader sequence produced low level background expression in rice. | LU Huafei MING Xiaotian QU Lijia LIU Meihua LI Jing GU Hongya CHEN Zhangliang | 2000 | Chinese Science Bulletin2000，45，3： | 5 |
| 3 | Mesenchymal stem cell treatment improves outcome of COVID-19 patients via multiple immunomodulatory mechanisms显示文摘The infusion of coronavirus disease 2019(COVID-19)patients with mesenchymal stem cells(MSCs)potentially improves clinical symptoms,but the underlying mechanism remains unclear.We conducted a randomized,single-blind,placebo-controlled(29 patients/group)phase II clinical trial to validate previous findings and explore the potential mechanisms.Patients treated with umbilical cord-derived MSCs exhibited a shorter hospital stay(P=0.0198)and less time required for symptoms remission(P=0.0194)than those who received placebo.Based on chest images,both severe and critical patients treated with MSCs showed improvement by day 7(P=0.0099)and day 21(P=0.0084).MSC-treated patients had fewer adverse events.MSC infusion reduced the levels of C-reactive protein,proinflammatory cytokines,and neutrophil extracellular traps(NETs)and promoted the maintenance of SARS-CoV-2-specific antibodies.To explore how MSCs modulate the immune system,we employed single-cell RNA sequencing analysis on peripheral blood.Our analysis identified a novel subpopulation of VNN2+hematopoietic stem/progenitorlike(HSPC-like)cells expressing CSF3R and PTPRE that were mobilized following MSC infusion.Genes encoding chemotaxis factors—CX3CR1 and L-selectin—were upregulated in various immune cells.MSC treatment also regulated B cell subsets and increased the expression of costimulatory CD28 in T cells in vivo and in vitro.In addition,an in vivo mouse study confirmed that MSCs suppressed NET release and reduced venous thrombosis by upregulating kindlin-3 signaling.Together,our results underscore the role of MSCs in improving COVID-19 patient outcomes via maintenance of immune homeostasis. | Rongjia Zhu Tingdong Yan Yingmei Feng Yan Liu Hongcui Cao Gongxin Peng Yanlei Yang Zhen Xu Jingqi Liu Wei Hou Xiaoyue Wang Zhe Li Luchan Deng Shihua Wang Jing Li Qin Han Hongling Li Guangliang Shan Yinghao Cao Xingyan An Jianshe Yan Zhonghui Zhang Huafei Li Xuebin Qu Jiaqi Zhu Shumin Zhou Jiao Wang Fengchun Zhang Jinming Gao Ronghua Jin Dayong Xu Yan-Qing Ma Tao Huang Shuang Peng Zhi Zheng Ilia Stambler Eric Gilson Lee Wei Lim Alexey Moskalev Antonio Cano Sasanka Chakrabarti Brun Ulfhake Huanxing Su Haoying Xu Sihuan Xu Feng Wei Holly MBrown-Borg Kyung-Jin Min Georgina Ellison-Hughes Calogero Caruso Kunlin Jin Robert Chunhua Zhao | 2021 | Cell Research2021，31，12： | 5 |
| 4 | A NATURAL GRADIENT ALGORITHM FOR THE SOLUTION OF LYAPUNOV EQUATIONS BASED ON THE GEODESIC DISTANCE显示文摘一个新框架基于弄弯的 Riemannian 歧管被建议由使用一个自然坡度降下算法并且作为客观函数拿测地学的距离计算 Lyapunov 矩阵方程的数字解决方案。而且,一个坡度降下算法基于古典欧几里德几何学的距离被提供与这个自然坡度降下算法作比较。而且,二的行为建议了算法并且常规修改结合坡度算法被二个模拟例子比较并且示威。由比较,自然坡度降下算法的集中速度是比两坡度降下算法快的,这被显示出并且常规修改在解决 Lyapunov 方程结合坡度算法。[从作者抽象] | Xiaomin Duan Huafei Sun Zhenning Zhang | 2014 | Journal of Computational Mathematics2014，32，1： | 5 |
| 5 | Numerical simulations of seepage flow in rough single rock fractures显示文摘To investigate the relationship between the structural characteristics and seepage flow behavior of rough single rock fractures,a set of single fracture physical models were produced using the WeierstrasseMandelbrot functions to test the seepage flow performance.Six single fractures,with various surface roughnesses characterized by fractal dimensions,were built using COMSOL multiphysics software.The fluid flow behavior through the rough fractures and the influences of the rough surfaces on the fluid flow behavior was then monitored.The numerical simulation indicates that there is a linear relationship between the average flow velocity over the entire flow path and the fractal dimension of the rough surface.It is shown that there is good agreement between the numerical results and the experimental data in terms of the properties a of the fluid flowing through the rough single rock fractures. | Qingang Zhang Yang Ju Wenbo Gong Liang Zhang Huafei Sun | 2015 | Petroleum2015，1，3： | 5 |
| 6 | Optimal control on special Euclidean group via natural gradient algorithm显示文摘Considering the optimal control problem about the control system of the special Euclidean group whose output only depends on its input is meaningful in practical applications. The optimal control considered here is described as the output matrix is as close as possible to the target matrix by adjusting the system input.The geodesic distance is adopted as the measure of the difference between the output matrix and the target matrix, and the trajectory of the control input obtained in the process is achieved. Furthermore, some numerical simulations are shown to illustrate our outcomes based on the natural gradient descent algorithm for optimizing the control system of the special Euclidean group. | Chunhui LI Erchuan ZHANG Lin JIU Huafei SUN | 2016 | Science China(Information Sciences)2016，59，11： | 4 |
| 7 | Computational and Experimental Study of Cooling Process in Coke Dry Quenching Experimental Shaft显示文摘Owing to its merits in energy savings, environmental protection and coke quality improvement, the Coke Dry Quenching (CDQ) technology is favorite in coke making industry today. In order to validate the mathematical model developed for the cooling process of real CDQ shaft, the one-seventh scale experimental setup was established. With the air as the working fluid and the coke as the packed bed, the coke and gas temperatures and the pressure drop in the cooling shaft were measured. A mathematical model based on the non-Darcian and non-thermal equilibrium model for the cooling process of the CDQ experimental shaft was presented. The computational results were compared to the experimental data. It was found that most numerical predictions were supported by the measured values. | Huafei Liu Xinxin Zhang Maolin Wu Yanhui Feng Yingbo Wang Dinan Wang Lie Xu Wenghua Zheng | 2002 | Journal of Thermal Science2002，11，2： | 2 |
| 8 | Mathematical Model for Fluid Flow and Heat Transfer in the Cooling Shaft of Coke Dry Quenching Unit显示文摘A mathematical model based on non-Darcian flow and two-phase model is developed for fluid flow and heat transfer in the cooling shaft of Coke Dry Quenching (CDQ) unit. The potential flow model is employed to simulate coke descending. Governing equations are solved by the SIMPLE algorithm on the collocated, non-orthogonal and body-fitted grids. The velocity of circulating gas and the temperature of coke and gas are obtained to study the effects of coke size distribution on flow and heat transfer behavior in the cooling shaft. It is found that the non-uniformity of gas velocity and the unevenness of coke temperature in the radial direction can be reduced if coke size distribution is improved. The gas velocity field and the temperature distribution of coke and gas are presented. | Huafei Liu Xinxin Zhang Lie Xu Mingdeng Wang | 2002 | Journal of Thermal Science2002，11，1： | 2 |
| 9 | Diabetes interferes with the bone formation by affecting the expression of transcription factors that regulate osteoblast differen-tiation 显示文摘 | Huafei LU Douglas K Louis C | 2003 | Endocrinology2003，144，1： | 1 |
| 10 | Identification of Cinobufagin and Resibufogenin as Inhibitors of Enterovirus 71 Infection显示文摘 | CHEN Jiawen XU Lin SUN Shiyang ZHANG Huafei MA Tonghui SU Weiheng JIANG Chunlai | 2014 | Chemical Research in Chinese Universities2014，30，6： | 1 |
| 11 | Research Progress of the Algebraic and Geometric Signal Processing显示文摘The investigation of novel signal processing tools is one of the hottest research topics in modern signal processing community. Among them, the algebraic and geometric signal processing methods are the most powerful tools for the representation of the classical signal processing method. In this paper, we provide an overview of recent contributions to the algebraic and geometric signal processing. Specifically, the paper focuses on the mathematical structures behind the signal processing by emphasizing the algebraic and geometric structure of signal processing. The two major topics are discussed. First, the classical signal processing concepts are related to the algebraic structures, and the recent results associated with the algebraic signal processing theory are introduced. Second, the recent progress of the geometric signal and information processing representations associated with the geometric structure are discussed. From these discussions, it is concluded that the research on the algebraic and geometric structure of signal processing can help the researchers to understand the signal processing tools deeply, and also help us to find novel signal processing methods in signal processing community. Its practical applications are expected to grow significantly in years to come, given that the algebraic and geometric structure of signal processing offer many advantages over the traditional signal processing. | TAO Ran LI Bingzhao SUN Huafei | 2013 | Defence Technology(防务技术)2013，9，1： | 1 |
| 12 | Automatic analysis and integration of architectural drawings显示文摘 | Lu Tong Yang Huafei Yang Ruoyu | 2005 | Computer-Aided Design2005，37，10： | 1 |
| 13 | Automatic analysis and integration of architectural drawings显示文摘 | LU Tong YANG Huafei YANG Ruoyu | 2007 | Interna- tional Journai on Document Analysis and Recognition2007，9，1： | 1 |
| 14 | International System and China’s Asia-Pacific Strategy显示文摘What impact does a shift in the global distribution of power have on the international order? According to the views of traditional realists,power transitions in the international order are usually accompanied by major wars,the best example being the two world wars of the twentieth century.China’s peaceful rise is conducive to the peace and stability of Asia and Pacific regions.The steady rise of China’s position and its role in dealing with international and regional problems have proved China’s success in 'cooperative security'.This paper analyzes the security order in the Asia-Pacific region1 that China wants to construct to provide important guarantees to its peaceful rise.Firstly,I review and compare key arguments about the transition of international systems and China’s Asia-Pacific strategy.Secondly,I investigate the dynamics between China’s peaceful rise and the 'cooperative security' which I think are the collective embodiments of modern transformation and the restructuring of China’s traditional strategic culture.Thirdly,I examine how to construct a mechanism of cooperation in the Asia-Pacific region to guarantee China’s peaceful rise on both political and economic levels.Economic cooperation and free trade in Asia-Pacific region is an important route to regional economic integrity which will guarantee China’s role in maintaining the political and economic security in the region. | Qiu Huafei | 2010 | Contemporary International Relations2010，20，1： | 1 |
| 15 | Diabetes interferes with the bone formation by affecting the expression of transcription factors that regulate osteoblast differentiation显示文摘 | Huafei LU Douglas Kraut Louis C | 2003 | Endocrinology2003，144，1： | 1 |
| 16 | Preparation and characterization of a metered dose transdermal spray for testosterone显示文摘The objective of the present work was to develop a metered dose transdermal spray(MDTS)formulation for transdermal delivery of testosterone and to characterize its efficacy.Testosterone release from a series of formulations was assessed in vitro.Skin from hairless mice was used in permeation experiments with Franz diffusion cells.The spray pattern,pump seal efficiency,average weight per metered dose and dose uniformity were evaluated.An optimized formulation containing 10%(w/v)testosterone,9%(v/v)azone and 91%(v/v)ethanol was based on good skin permeation and acceptable drug concentration and permeation enhancer(PE)content.A skin irritation study indicated that the formulation was non-irritating in a rat model.An in vivo pharmacokinetic study indicated that the optimized formulation showed a different plasma concentration-time profile from that of the commercially available product Testopatchs.The Testopatchs product demonstrated a more sustainable drug release.The evaluation of the testosterone MDTS indicated that it could deliver reproducible amounts of the formulation per actuation.The results obtained showed that the MDTS is a potential alternative therapeutic system for transdermal testosterone delivery. | Wangding Lu Huafei Luo Yubo Wu Zhuangzhi Zhu Hao Wang | 2013 | Acta Pharmaceutica Sinica B2013，3，6： | 1 |
| 17 | Graves diabetes interferes with the bone formation by affecting the expression of transcription factors that regulate osteoblasts differentiation 显示文摘 | Huafei L Douglas K Louis C | 2003 | Endocrinology2003，144，1： | 1 |
| 18 | Laguerre Isoparametric Hypersurfaces in R4显示文摘 | Li Tongzhu Sun Huafei | 2011 | Acta Mathematica Sinica English Series2011，28，： | 1 |
| 19 | Potentiating antilymphoma efficacy of chemotherapy using a liposome for integration of CD20 targeting, ultra-violet irradiation polymerizing, and controlled drug delivery显示文摘 | Cong Wu Huafei Li He Zhao Weiwei Zhang Yan Chen Zhanyi Yue Qiong Lu Yuxiang Wan Xiaoyu Tian Anmei Deng | 2014 | Nanoscale Research Letters2014，，： | 1 |
| 20 | Application of gradient descent algorithms based on geodesic distances显示文摘In this paper, the Riemannian gradient algorithm and the natural gradient algorithm are applied to solve descent direction problems on the manifold of positive definite Hermitian matrices, where the geodesic distance is considered as the objective function. The first proposed problem is the control for positive definite Hermitian matrix systems whose outputs only depend on their inputs. The geodesic distance is adopted as the difference of the output matrix and the target matrix. The controller to adjust the input is obtained such that the output matrix is as close as possible to the target matrix. We show the trajectory of the control input on the manifold using the Riemannian gradient algorithm. The second application is to compute the Karcher mean of a finite set of given Toeplitz positive definite Hermitian matrices, which is defined as the minimizer of the sum of geodesic distances. To obtain more efficient iterative algorithm than traditional ones, a natural gradient algorithm is proposed to compute the Karcher mean. Illustrative simulations are provided to show the computational behavior of the proposed algorithms. | Xiaomin DUAN Huafei SUN Linyu PENG | 2020 | Science China(Information Sciences)2020，63，5： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员