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| 1 | Early kidney injury during long-term adefovir dipivoxil therapy for chronic hepatitis B显示文摘AIM: To evaluate urine β2-microglobulin(β2-M), retinol-binding protein(RBP) excretion, and renal impairment with adefovir dipivoxil(ADV) for chronic hepatitis B. METHODS: We enrolled 165 patients with chronic hepatitis B infection who were treated with ADV monotherapy(n = 90) or ADV plus lamivudine combination therapy(n = 75). An additional 165 chronic hepatitis B patients treated with entecavir were recruited as controls. We detected serum creatinine, urine β2-M, and RBP levels, and estimated the glomerular filtration rate(e GFR) at the initiation of antiviral therapy and every 6 mo for a period of five years. RESULTS: Urine β2-M abnormalities were observed in patients during the first(n = 3), second(n = 7), third(n = 11), fourth(n = 16), and fifth(n = 21) year of ADV treatment. Urinary RBP abnormalities were observed in patients during the first(n = 2), second(n = 8), third(n = 12), fourth(n = 15), and fifth(n = 22) year of ADV treatment. e GFR decreased 20%-30% from baseline in 20 patients, 30%-50% in 12 patients, and > 50% in 3 patients during the five years of treatment. Further analysis indicated that decreases in e GFR of ≥ 30% relative to the baseline level correlated significantly with urine RBP and β2-M abnormalities. In contrast, both serum creatinine and e GFR remained stable in patients treated with entecavir, and only one of these patients developed a urine β2-M abnormality, and two developed urine RBP abnormalities during the five years of treatment. CONCLUSION: Urine RBP and β2-M are biomarkers of renal injury during long-term ADV treatment for chronic hepatitis B, and indicate when treatment should be switched to entecavir. | Hong-Yu Jia Feng Ding Jian-Yang Chen Jiang-Shan Lian Yi-Min Zhang Lin-Yan Zeng Dai-Rong Xiang Liang Yu Jian-Hua Hu Guo-Dong Yu Huan Cai Ying-Feng Lu Lin Zheng Lan-Juan Li Yi-Da Yang | 2015 | World Journal of Gastroenterology2015，21，12： | 22 |
| 2 | Coinfection with influenza A virus enhances SARS-CoV-2 infectivity显示文摘The upcoming flu season in the Northern Hemisphere merging with the current COVID-19 pandemic raises a potentially severe threat to public health.Through experimental coinfection with influenza A virus(IAV)and either pseudotyped or live SARS-CoV-2 virus,we found that IAV preinfection significantly promoted the infectivity of SARS-CoV-2 in a broad range of cell types.Remarkably,in vivo,increased SARS-CoV-2 viral load and more severe lung damage were observed in mice coinfected with IAV.Moreover,such enhancement of SARS-CoV-2 infectivity was not observed with several other respiratory viruses,likely due to a unique feature of IAV to elevate ACE2 expression.This study illustrates that IAV has a unique ability to aggravate SARS-CoV-2 infection,and thus,prevention of IAV infection is of great significance during the COVID-19 pandemic. | Lei Bai Yongliang Zhao Jiazhen Dong Simeng Liang Ming Guo Xinjin Liu Xin Wang Zhixiang Huang Xiaoyi Sun Zhen Zhang Lianghui Dong Qianyun Liu Yucheng Zheng Danping Niu Min Xiang Kun Song Jiajie Ye Wenchao Zheng Zhidong Tang Mingliang Tang Yu Zhou Chao Shen Li Zhou Yu Chen Huan Yan Ke Lan Ke Xu | 2021 | Cell Research2021，31，4： | 16 |
| 3 | Preliminary study on the production of transgenic mice harboring hepatitis B virus X gene显示文摘INTRODUCTIONDespiteoverwhelmingepidemiologicalevidencelinkingpersistentHepatitisBVirus(HBV)infectionandthedevelopmentofhepato... | ZHU Huan Zhang 1, CHENG Guo Xiang 2, CHEN Jian Qu 2, KUANG Shu Yuan 3, CHENG Yong 2, ZHANG Xin Li 1, Ll Hou Da 2, XU Shao Fu 2, SHI Jing Quan 1, QIAN Geng Sun 3 and GU Jian Ren 3 | 1998 | World Journal of Gastroenterology1998，4，6： | 14 |
| 4 | Fermentation-enabled wellness foods:A fresh perspective显示文摘Fermented foods represent an important segment of current food markets,especially traditional or ethnic food markets.The demand for efficient utilization of agrowastes,together with advancements in fermentation technologies(microbial-and enzyme-based processing),are stimulating rapid growth and innovation in the fermented food sector.In addition,the health-promoting benefits of fermented foods are attracting increasingly attention.The microorganisms contained in many common fermented foods can serve as“microfactories”to generate nutrients and bioactives with specific nutritional and health functionalities.Herein,recent research relating to the manufacture of fermented foods are critically reviewed,placing emphasis on the potential health benefits of fermentation-enabled wellness foods.The importance of the correct selection of microorganisms and raw materials and the need for precise control of fermentation processes are explored.Major knowledge gaps and obstacles to fermented food production and market penetration are discussed.The importance of integrating multidisciplinary knowledge,communicating with consumers,establishing regulatory frameworks specifically for fermentation-enabled wellness foods and functional fermented foods,are highlighted. | Huan Xiang Dongxiao Sun-Waterhouse Geoffrey I.N.Waterhouse Chun Cui Zheng Ruan | 2019 | Food Science and Human Wellness2019，8，3： | 12 |
| 5 | Detection of Pseudorabies Virus Antibodies in Human Encephalitis Cases显示文摘Pseudorabies virus(PRV),a veterinary pathogen that infects domestic animals as well as wild animals such as wild boar and feral swine,was recently reported to infect human and led to endophthalmitis and encephalitis.A retrospective seroepidemiologic survey was conducted using 1,335 serum samples collected from patients with encephalitis and ELISA positive rates were 12.16%,14.25%,and 6.52%in 2012,2013,and 2017,respectively. | LI Xiang Dong FU Shi Hong CHEN Ling Yan LI Fan DENG Jun Hua LU Xuan Cheng WANG Huan Yu TIAN Ke Gong | 2020 | Biomedical and Environmental Sciences2020，33，6： | 9 |
| 6 | The Effect of PCDH15 Gene Variations on the Risk of Noise-induced Hearing Loss in a Chinese Population显示文摘导致噪音的听觉损失(NIHL ) 是在环境、基因的因素之间的相互作用引起的复杂疾病。这研究调查了在 protocadherin 的基因可变性是否联系了 15 (PCDH15 ) 在一张中国人口位于增加的危险性下面到 NIHL 的发展。结果证明与 rs11004085 的 TT 遗传型相比, CT/CC 遗传型与 NIHL 的增加的风险被联系[调整机会比率(或)= 2.64;95% 信心间隔(CI ) :1.14-6.11, P = 0.024 ] 。另外,在 rs11004085 和 rs978842 之间的重要相互作用基因变化和噪音暴露在高级暴露组被观察(P < 0.05 ) 。而且,当与噪音暴露的高水平结合了时,风险 haplotype TAGCC 被观察(P < 0.05 ) 。因此,我们的学习证实在 PCDH15 的基因变化在人修改危险性到 NIHL 开发。 | XU Xiang Rong WANG Jing Jing YANG Qiu Yue JIAO Jie HE Li Hua YU Shan Fa GU Gui Zhen CHEN Guo Shun ZHOU Wen Hui WU Hui LI Yan Hong ZHANG Huan Ling ZHANG Zeng Rui JIN Xian Ning | 2017 | Biomedical and Environmental Sciences2017，30，2： | 9 |
| 7 | Analysis of Health Service Utilization and its Influencing Factors among Patients with Pneumoconiosis in China显示文摘Pneumoconiosis,an interstitial lung disease that occurs from breathing in certain kinds of damaging dust particles,is a major occupational disease in China.Patients diagnosed with occupational pneumoconiosis can avail of free medical treatment,whereas patients without a diagnosis of occupational diseases cannot not claim free medical treatment in most provinces from the government before 2019.This study aimed to analyze the priority of medical facility selection and its influencing factors among patients with pneumoconiosis. | WANG Huan Qiang JIA Jun Lin JIANG Zhao Qiang JIN Qi LI Dong Xia LING Rui Jie LI Ying CUI Ping CHEN Gang ZHAO Hong Yu LI Yan WEN Ke LYU Xiang Pei LOU Jian Lin LI Tao | 2021 | Biomedical and Environmental Sciences2021，34，1： | 9 |
| 8 | Polymorphisms of three gene-derived STS on pig chromosome 13q41 are associated with susceptibility to enterotoxigenic Escherichia coli F4ab/ac in pigs显示文摘Neonatal diarrhea caused by enterotoxigenic Escherichia coli(ETEC)F4 is a common and serious disease,resulting in significant economical loss in the pig industry.The locus encoding ETEC F4 receptor has been mapped to pig chromosome(SSC)13q41,and one of the most significantly linked markers is S0075.In this study,we selected three genes including SLC12A8,MYLK and KPNA1 from a chromosomal region flanking S0075 on SSC13 to develop pig specific sequence tagged sites(STS). Seven single nucleotide polymorphisms were identified in the three pig STS using DNA of four full-sib susceptible and resistant animals in a White Duroc×Erhualian intercross.All grandparents,parents and 755 offspring in the intercross were genotyped for three polymorphisms,including SLC12A8 g.159A>G,MYLK g.1673A>G and KPNA1 g.306A>G.Family-based transmission disequilibrium test(TDT) revealed that all polymorphisms and the corresponding haplotypes are significantly associated with ETEC F4ab/ac(especially F4ac)brush border adhesion phenotypes,indicating that these polymor- phism are in linkage disequlibrium with causal mutation(s)of the gene encoding ETEC F4ab/ac receptor. Our results strengthen the evidence for the involvement of SSC13q41 in high acquiring risk of ETEC F4ab/ac infection,and provide novel polymorphic markers for fine mapping of the ETEC F4ab/ac receptor locus. | HUANG Xiang 1 ,REN Jun 1 ,YAN XueMing 1,2 ,PENG QiuLing 1 ,TANG Huan 1 ,ZHANG Bo 1 ,JI HuaYuan 1 , YANG ShuJin1&HUANG LuSheng 1 1Key Laboratory for Animal Biotechnology of Jiangxi Province and the Ministry of Agriculture of China,Jiangxi Agricultural University, Nanchang 330045,China 2Department of Biology,Nanchang University of Science and Technology,Nanchang 330038,China | 2008 | Science China(Life Sciences)2008，51，7： | 8 |
| 9 | Modulation of Guard Cell Turgor and Drought Folerance by a Peroxisomal Acetate-Malate Shunt显示文摘 | Huan Dong Ling Bai Yu Zhang Guozeng Zhang Yanqing Mao Lulu Min Fuyou Xiang Dongdong Qian Xiaohong Zhu Chun-Peng Song | 2018 | Molecular Plant2018，11，10： | 6 |
| 10 | Metamerism Appreciation of Jadeite-Jade Green under the Standard Light Sources D_(65),A and CWF显示文摘We tested 288 pieces of the polished cabochon jadeite-jade with high quality green and smooth surfaces using the colorimeter Color i5 based on the CIE 1976 L~*a~*b~* uniform color space. The color changes after alternating three CIE standard light sources D_(65),A and CWF were compared,and the degree of metamerism was evaluated. The results show that the CIE standard light sources D_(65),A and CWF increase the chroma of green and turn bluish green into vivid green,which are similar or to nearly colorless and transparent glass-like samples with fine textures. When the three light sources were individually alternated,the lightness of the jadeite-jades showed little change,but the tone changed significantly. Metamerism occurred only in 3 pairs among the 16 samples that were selected by cluster analysis for quality,and the metamerism colors were highly consistent of L~*D_(65)∈(43.47,46.75),C~*D_(65)∈(65.20,68.80) and ho~*D_(65)∈(138.10,140.23). We can conclude that the jadeite-jade green gradually turns to blue when the color temperature of the light source increases. But when considering both the light sources and the samples,D_(65) is more suitable to be the light source of jadeite-jade green when compared with the light sources CWF and A. Compared with the CIE standard green and high chroma green,high-quality jadeite-jade green has a slight yellow tone,low lightness and high chroma. The special metamerism index decreased to 1 when the light source alternated among D_(65),A and CWF. Therefore,the color of jadeite-jade green might be slightly influenced by alternating of the light sources. | GUO Ying WANG Huan LI Xiang DONG Shirong | 2016 | Acta Geologica Sinica(English Edition)2016，90，6： | 5 |
| 11 | Hypoglycemic polysaccharides from Auricularia auricula and Auricularia polytricha inhibit oxidative stress,NF-κB signaling and proinflammatory cytokine production in streptozotocin-induced diabetic mice显示文摘Auricularia auricula(AA)and Auricularia polytricha(AP)are popular edible fungi.This study successfully produced hypoglycemic polysaccharides from un-smashed or smashing and sieving(through a 10-mesh sieve)AA and AP(termed as AAP/AAP-10 and APP/APP-10)via scalable processes(water extraction,ethanolic precipitation and deproteinization).This is the first report to compare the effectiveness of AAP and APP in combating streptozotocin-induced oxidative stress and diabetes-related changes in mice(body weight,fasting blood glucose,serum insulin,proinflammatory mediator and cytokines,oxidative stress-related products,antioxidant enzymes).APP and AAP with different molecular weights and monosaccharide molar ratios could be therapeutic options for diabetes with a low dose(100 mg/kg/day)likely working better.At the same dose,APP generally performed more effective than AAP,and AAP-10/APP-10 seemed slightly more beneficial than AAP/APP.One mechanism underlying these antidiabetic functions might involve the NF-κB and associated signalling pathways.AP is cheaper than AA,thereby representing a favorable source of functional polysaccharides. | Huan Xiang Dongxiao Sun-Waterhouse Chun Cui | 2021 | Food Science and Human Wellness2021，10，1： | 5 |
| 12 | Effects of neferine on Kv4.3 channels expressed in HEK293 cells and ex vivo electrophysiology of rabbit hearts显示文摘目的: Neferine 是从 Nelumbo nucifera (Gaertn ) 的种子胚胎孤立的 isoquinoline 碱,它举办许多生物活动。在这研究,我们在 Kv4.3 隧道上检验了 neferine 的效果,一个主要贡献者到短暂外面的水流(我 到在兔子心的),并且在兔子 hearts.Methods 的前 vivo electrophysiology 上:整个房间的 Kv4.3 水流在用补丁夹钳表示人的心脏的 Kv4.3 隧道的 HEK293 房间被记录技术。兔子的动脉地酒的楔离开了室( LV )被准备,并且 transmembrane 行动潜力同时和 transmural electrocardiography ( ECG )与漂浮的 microelectrodes 从 epicardial ( Epi )和 endocardial ( Endo )地点被记录 .Results : Neferine ( 0.1-100 μ ; mol/L ) dose-dependently 并且 reversibly 禁止的 Kv4.3 水流( IC 50价值是 8.437 μ ; mol/L ,并且在 100 μ 的最大的抑制; mol/L 是44.12%)。Neferine (10 μ mol/L ) 引起了 Kv4.3 水流,和不变的 inactivation 曲线的否定移动的不变的激活曲线的积极移动。而且, neferine (10 μ mol/L ) 加速了 inactivation 然而并非 Kv4.3 水流的激活,并且显著地从 inactivation 减缓了 Kv4.3 水流的恢复。Kv4.3 水流的导致 Neferine 的堵住是频率依赖者。在兔子 LV 的动脉地酒的楔, neferine ( 1 , 3 ,和 10 μ ; mol/L ) dose-dependently 在 Epi 和 Endo 地点延长了 QT 间隔和行动潜力持续时间( APD ),并且在 Epi sites.Conclusion 引起了 APD 10的戏剧的增加: Neferine 由堵住开的状态并且使州的隧道失去活性多半禁止 Kv4.3 隧道,它在兔子心的 Epi 地点贡献 APD 10的 导致neferine 的戏剧的增加。 | Chen WANG Yu-fang CHEN Xiao-qing QUAN Huan WANG RuiZHANG Jun-hua XIAO Jia-ling WANG Cun-tai ZHANG Ji-zhou XIANG Qiang TANG | 2015 | Acta Pharmacologica Sinica2015，36，12： | 4 |
| 13 | Experiences and challenges in the health protection of medical teams in the Chinese Ebola treatment center,Liberia:a qualitative study显示文摘Background:Health care workers are at the frontline in the fight against infectious disease,and as a result are at a high risk of infection.During the 2014-2015 Ebola outbreak in West Africa,many health care workers contracted Ebola,some fatally.However,no members of the Chinese Anti-Ebola medical team,deployed to provide vital medical care in Liberia were infected.This study aims to understand how this zero infection rate was achieved.Methods:Data was collected through 15 in-depth interviews with participants from the People’s Liberation Army of China medical team which operated the Chinese Ebola Treatment Center from October 2014 to January 2015 in Liberia.Data were analysed using systematic framework analysis.Results:This study found numerous bio-psycho-socio-behavioural risk factors that directly or indirectly threatened the health of the medical team working in the Chinese Ebola Treatment Center.These factors included social and emotional stress caused by:(1)the disruption of family and social networks;(2)adapting to a different culture;(3)and anxiety over social and political unrest in Liberia.Exposure to Ebola from patients and local co-workers,and the incorrect use of personal protective equipment due to fatigue was another major risk factor.Other risk factors identified were:(1)shortage of supplies;(2)lack of trained health personnel;(3)exposure to contaminated food and water;(4)and long working hours.Comprehensive efforts were taken throughout the mission to mitigate these factors.Every measure was taken to prevent the medical team’s exposure to the Ebola virus,and to provide the medical team with safe,comfortable working and living environments.There were many challenges in maintaining the health safety of the team,such as the limited capability of the emergency command system(the standardized approach to the command,control,and coordination of an emergency response),and the lack of comprehensive international protocols for dealing with emerging infectious disease pandemics.Conclusions:The comprehensive and multidisciplinary measures employed to protect the health of the medical team proved successful even in Liberia’s resource-limited setting.The global health community can learn valuable lessons from this experience which could improve the safety of health care workers in future emergencies.These lessons include:establishing capable command systems;implementing effective coordination mechanisms;providing adequate equipment;providing training for medical teams;investing in the development of global health professionals;and improving research on ways to protect health care workers. | Ying Li Huan Wang Xu-Rui Jin Xiang Li Michelle Pender Cai-Ping Song Sheng-Lan Tang Jia Cao Hao Wu Yun-Gui Wang | 2018 | Infectious Diseases of Poverty2018，7，1： | 4 |
| 14 | Deep eutectic solvents and alkaline extraction of protein from seabuckthorn seed meal: a comparison study显示文摘Seabuckthorn seed meal(SSM) is a waste of oil extraction industry that rich in protein. In order to seek suitable protein extraction method, three different deep eutectic solvents(DESs)(including choline chlorideglycerol, choline chloride-oxalic acid and choline chloride-urea) were developed for extracting protein from SSM and compared with alkaline. Result indicated that alkaline could effectively extract 56.9% protein from SSM and its protein content was 73.1%, higher than DES at 31.0%-41.4% and 64.3%-67.5%, respectively. However, compared to alkali, DES led to a product with less β-sheet, more β-turn, more essential amino acids, higher total amino acid content, especially choline chloride-urea which extracted protein showing an integrated and similar protein weight distribution compared to SSM. Also, this protein extracted chloride-urea showed a highest digestibility in vitro(by pepsin)(54.2%). These results indicated that choline chloride-urea extraction is better than alkaline extraction for SSM. | Junjie Lin Huan Xiang Dongxiao Sun-Waterhouse Chun Cui Wei Wang | 2022 | Food Science and Human Wellness2022，11，4： | 4 |
| 15 | Reductive demetalation of manganese corroles:The substituent effect显示文摘锰 corroles 的减少的 demetalation 在 CH2Cl2/HCl 被调查(水) 由把 SnCl2 用作减少代理人的溶剂。demetalation 收益显著地取决于 corrole macrocycle 的取代者,这被发现。充满电子的锰 corrole 比电子缺乏的更容易经历减少的 demetalation。锰 5,10,15-tris (苯基) 的孤立的减少的 demetalation 收益在现在的系统的 corrole 是中等的(46%) 。至于电子缺乏的 Mn (III ) 5,10,15-tris (pentafluorophenyl ) corrole,在 HOAc 鈥揌2 SO4 (V/V = 3:1 ) 的导致酸的 demetalation 与 67% 的孤立的收益更好。 | Hai Yang Liu Ling Chen Fei Yam Hai Ying Zhan Xiao Ying Xiang Li Wang Huan Feng Jiang Chi Kwong Chang | 2008 | Chinese Chemical Letters2008，19，8： | 3 |
| 16 | Poly IC pretreatment suppresses B cell-mediated lupus-like autoimmunity through induction of Peli1显示文摘 | Yan Wang Jia Yuan Dongfang Dai Junli Liu Jing Xu Xiang Miao Huan Wang Chaoming Mao Yichuan Xiao | 2018 | Acta Biochimica et Biophysica Sinica2018，50，9： | 3 |
| 17 | Study on the Influence of Airgun Excitation Conditions on Airgun Signals and Travel Time Variation Measurements显示文摘Because of the different excitation conditions of the airgun source,there will be subtle differences in airgun signals.Travel time variation of airgun signals often mix into source information which can’t fully reflect the evolution of the medium.This article uses the airgun signals from the Binchuan Transmitting Seismic Station to analyze the airgun signal′s characteristics of phase and correlation.We conducted a comparative analysis of the effects of the pair difference method and the deconvolution method on eliminating the influence of the excitation conditions in travel time variation.The results show that:(1)The pressure pulse and its subsequent wave of airgun source wavelet are less affected by excitation conditions that we can use it to obtain high-precision excitation moments.(2)Deconvolution can improve the correlation of the airgun signal.(3)The pair difference method can’t eliminate the influence of excitation conditions in travel time variation.Deconvolution can reduce excitation condition interference and the influence of the excitation condition in the travel time variation after deconvolution of the vertical signal is significantly reduced. | XIANG Ya YANG Runhai WANG Bin ZHOU Yunyao LU Yongqing WU Huan QI Junwei PENG Jing | 2019 | Earthquake Research in China2019，33，2： | 3 |
| 18 | Relationships between daily total fluoride intake and dental fluorosis and dental caries显示文摘Objective:To explore the relationships between the daily total intake of fluoride,dental fluorosis and dental caries. Methods: An epidemiological method was used to investigate the daily total intake of fluoride,dental fluorosis,and dental caries among 236 and 290 children aged 8-13 years in a severe endemic area and in a non-fluorosis control area,respectively. The children were divided into eight subgroups according to each child’s estimated daily total intake of fluoride. The prevalence of dental fluorosis and dental caries in each group was calculated. Results: As expected,elevated levels of fluoride intake were significantly associated with a higher prevalence of dental fluorosis and an increasing amount of more severe defect dental fluorosis. When the daily total F intake was 2.78 mg/child/day,the prevalence of dental fluorosis was nearly 100%,with the prevalence of defect dental fluorosis increasing with increasing fluoride intake. There was also a significant negative(inverse) dose-response relationship between the daily total intake of fluoride and the overall preva-lence of dental caries,the prevalence of which decreased when the daily total intake of fluoride increased up to 3.32 mg/child/day. However,at higher levels of daily total intake of fluoride the prevalence of dental caries increased,giving rise to a U-shaped dose-response relationship curve. Conclusion: It is important to monitor total fluoride exposure and protect children from excessive fluoride intake,especially during the years of tooth development. | Quanyong Xiang Minghao Zhou Ming Wu Xinya Zhou Li Lin Jiuning Huan Youxing Liang | 2009 | Journal of Nanjing Medical University2009，23，1： | 3 |
| 19 | cDNA cloning and expression pattern of two enolase genes from the Chinese oak silkworm, Antheraea pernyi显示文摘在这研究,二 enolase 基因从中国橡树蚕被孤立并且描绘, Antheraea perny,它被指定为 enolase 我和 II 分别地。enolase 我 cDNA 顺序是有编码 433 氨基酸的 1302 bp 的一个开的读物框架(ORF ) 的 1712 bp。enolase II cDNA 顺序是有编码 431 氨基酸的 1296 bp 的 ORF 的 1549 bp。二基因的氨基酸序列分享 enolase 的几个保存特征 / 地点。我显示出的 Antheraea pernyi enolase 93%97% 顺序身份到迄今为止可得到的 lepidopterans 的 enolases,到另外的无脊椎动物的 enolases 的 75%82% 身份,到包括脊椎动物的另外的有机体的 enolases 的 60%72% 身份,植物,和真菌。Antheraea pernyi enolase II 显示出 84% 身份到 Bombyx mori enolase II,而是 60% 身份到 A。pernyi enolase 我。在种系发生的树上, enolase II 从 A 定序。pernyi 和 B。mori 清楚地包括 A 与更高的有机体的 enolase 序列的多数被分开。pernyi 和 B。我定序的 mori enolase。由顺序比较和种系发生的分析,我们从 A 建议那 enolase II。pernyi 和 B。mori 可以是 enolase 总科的一个新成员。Antheraea pernyi enolase 我而 enolase II mRNA 在睾丸和卵巢明确地被表示, mRNA 在所有测试纸巾被发现,建议 enolase II 基因的产品可能与复制有关。抄本许多 A。pernyi enolase 我基因在冷吃惊以后并且显著地是显著地下面调整的在热吃惊以后起来调整,建议那 A。pernyi enolase 我基因可能由温度应力是可诱导的。 | Yanqun Liu Yuping Li Huan Wang Runxi Xia Xisheng Li Haolei Wan Li Qin Defu Jiang Cheng Lu Zhonghuai Xiang | 2010 | Acta Biochimica et Biophysica Sinica2010，42，11： | 2 |
| 20 | Evaluation of the biocontrol potential of Aspergillus welwitschiae against the root-knot nematode Meloidogyne graminicola in rice(Oryza sativa L.)显示文摘The root-knot nematode Meloidogyne graminicola is considered one of the most devastating pests in rice-producing areas,and nematicides are neither ecofriendly nor cost effective.More acceptable biological agents are required for controlling this destructive pathogen.In this study,the biocontrol potential of Aspergillus welwitschiae AW2017 was investigated in laboratory and greenhouse experiments.The in vitro ovicidal and larvicidal activities of A.welwitschiae metabolites were tested on M.graminicola in laboratory experiments.The effect of A.welwitschiae on the attraction of M.graminicola to rice and the infection of rice by M.graminicola was evaluated in a greenhouse.The bioagent AW2017 displayed good nematicidal potential via its ovicidal and larvicidal action.The best larvicidal activity was observed at a concentration of 5×AW2017,which caused an 86.2%mortality rate at 48 h post inoculation.The highest ovicidal activity was recorded at a concentration of 5×AW2017,which resulted in an approximately 47.3%reduction in egg hatching after 8 d compared to the control.Under greenhouse conditions,the application of A.welwitschiae significantly reduced the root galls and nematodes in rice roots compared to the control.At a concentration of 5×AW2017,juveniles and root galls in rice roots at 14 d post inoculation(dpi)were reduced by 24.5 and 40.5%,respectively.In addition,the attraction of M.graminicola to rice roots was significantly decreased in the AW2017 treatment,and the development of nematodes in the AW2017-treated plants was slightly delayed compared with that in the PDB-treated control plants.The results indicate that A.welwitschiae is a potential biological control agent against M.graminicola in rice. | LIU Ying DING Zhong PENG De-liang LIU Shi-ming KONG Ling-an PENG Huan XIANG Chao LI Zhong-cai HUANG Wen-kun | 2019 | Journal of Integrative Agriculture2019，18，11： | 2 |
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