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| 1 | Over-expression of small ubiquitin-like modifier proteases 1 predicts chemo-sensitivity and poor survival in non-small cell lung cancer显示文摘 | Mu Juwei Zuo Yong Yang Wenjing Chen Zhaoli Liu Ziyuan Tu Jun Li Yan Yuan Zuyang Cheng Jinke He Jie | 2014 | Chinese Medical Journal2014，，23： | 7 |
| 2 | Structure of the intact 14-subunit human cytochrome c oxidase显示文摘 | Shuai Zong Meng Wu Jinke Gu Tianya Liu Runyu Guo Maojun Yang | 2018 | Cell Research2018，28，10： | 5 |
| 3 | Traditional Chinese medicines and their active ingredients sensitize cancer cells to TRAIL-induced apoptosis显示文摘The rapidly developing resistance of cancers to chemotherapy agents and the severe cytotoxicity of such agents to normal cells are major stumbling blocks in current cancer treatments.Most current chemotherapy agents have significant cytotoxicity,which leads to devastating adverse effects and results in a substandard quality of life,including increased daily morbidity and premature mortality.The death receptor of tumor necrosis factor-related apoptosis-inducing ligand(TRAIL)can sidestep p53-dependent pathways to induce tumor cell apoptosis without damaging most normal cells.However,various cancer cells can develop resistance to TRAIL-induced apoptosis via different pathways.Therefore,it is critical to find an efficient TRAIL sensitizer to reverse the resistance of tumor cells to TRAIL,and to reinforce TRAIL’s ability to induce tumor cell apoptosis.In recent years,traditional Chinese medicines and their active ingredients have shown great potential to trigger apoptotic cell death in TRAIL-resistant cancer cell lines.This review aims to collate information about Chinese medicines that can effectively reverse the resistance of tumor cells to TRAIL and enhance TRAIL’s ability to induce apoptosis.We explore the therapeutic potential of TRAIL and provide new ideas for the development of TRAIL therapy and the generation of new anticancer drugs for human cancer treatment.This study involved an extensive review of studies obtained from literature searches of electronic databases such as Google Scholar and PubMed.'TRAIL sensitize'and'Chinese medicine'were the search keywords.We then isolated newly published studies on the mechanisms of TRAIL-induced apoptosis.The name of each plant was validated using certified databases such as The Plant List.This study indicates that TRAIL can be combined with different Chinese medicine components through intrinsic or extrinsic pathways to promote cancer cell apoptosis.It also demonstrates that the active ingredients of traditional Chinese medicines enhance the sensitivity of cancer cells to TRAIL-mediated apoptosis.This provides useful information regarding traditional Chinese medicine treatment,the development of TRAIL-based therapies,and the treatment of cancer. | Bingyu SUN Yongqiang LIU Danhua HE Jinke LI Jiawei WANG Wulin WENS Ming HONG | 2021 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2021，22，3： | 3 |
| 4 | Photothermal and pH dual-responsive self-healing coating for smart corrosion protection显示文摘A novel self-healing coating with photothermal and pH dual-responsive properties has been designed to protect carbon steel against corrosion by loading the stimuli-responsive microcapsules into a shape memory epoxy coating. The sandwich-like microcapsules were based on reduced graphene oxide/mesoporous silica(r GO@MS) assembled with a p H-responsive poly(N,N-dimethylaminoethyl methacrylate)(PDMAEMA) layer, and were loaded with benzotriazole(BTA) inhibitors(abbreviated as rGO@MS-P-BTA). Under near-infrared(NIR) light irradiation, the prominent photothermal effect of rGO could not only elevate the coating temperature to activate the shape memory effect and close the coating scratch, but also facilitate the release of corrosion inhibitors to suppress the corrosion activity. Moreover,the PDMAEMA as a p H-driven “gatekeeper” realized the controlled release of BTA from microcapsules at acid conditions. The surface morphology analysis, electrochemical impedance spectroscopy(EIS), and scanning electrochemical microscopy(SECM) were performed to evaluate the self-healing performance of the composite coatings. The results showed that the combination of NIR light and p H-responsive selfhealing effects endowed the coating with short healing time and prominent healing efficiency. | Yao Huang Panjun Wang Weimin Tan Wenkui Hao Lingwei Ma Jinke Wang Tong Liu Fan Zhang Chenhao Ren Wei Liu Dawei Zhang | 2022 | Journal of Materials Science & Technology2022，，12： | 2 |
| 5 | Study on economic development of Inner Mo--ngolia based on energy 显示文摘 | SONG YUCHEN LIU JINKE | 2012 | Advanced Materials Research2012，，6： | 1 |
| 6 | Nanoparticle motion trajectories and deposition in an inlet channel of wall-flow diesel particulate filter显示文摘 | Yunqing Liu Jinke Gong Jun Fu Hao Cai Gang Long | 2008 | Journal of Aerosol Science2008，，4： | 1 |
| 7 | Nanoparticle mo- tion trajectories and deposition in an inlet channel of wall - flow diesel particulate filter 显示文摘 | Yunqing Liu Jinke Gong Jun Fu | 2009 | Aerosol Science2009，40，： | 1 |
| 8 | Conversion of mouse fibroblasts into oligodendrocyte progenitor-like cells through a chemical approach显示文摘Transplantation of oligodendrocyte progenitor cells (OPCs) is a promising way for treating demyelinating diseases. However, generation of scalable and autologous sources of OPCs has proven difficult. We previously established a chemical condition M9 that could specifically initiate neural program in mouse embryonic fibroblasts. Here we found that M9 could induce the formation of colonies that undergo mesenchymal-to-epithelial transition at the early stage of reprogramming. These colonies may represent unstable and neural lineage-restricted intermediates that have not established a neural stem cell identity. By modulating the culture signaling recapitulating the principle of OPC development, these intermediate cells could be reprogrammed towards OPC fate. The chemical-induced OPC-like cells (ciOPLCs) resemble primary neural stem cell-derived OPCs in terms of their morphology, gene expression, and the ability of self-renewal. Upon differentiation, ciOPLCs could produce functional oligodendrocytes and myelinate the neuron axons in vitro, validating their OPC identity molecularly and functionally. Therefore, our study provides a non-integrating approach to OPC reprogramming that may ultimately provide an avenue to patient-specific cell-based or in situ regenerative therapy. | Chang Liu Xu Hu Yawen Li Wenjie Lu Wenlin Li Nan Cao Saiyong Zhu Jinke Cheng Sheng Ding Mingliang Zhang | 2019 | Journal of Molecular Cell Biology2019，11，6： | 1 |
| 9 | Identification of two migratory colon ILC2 populations differentially expressing IL-17A and IL-5/IL-13显示文摘Group 2 innate lymphoid cells(ILC2s)play important tissue resident roles in anti-parasite immunity,allergic immune response,tissue homeostasis,and tumor immunity.ILC2s are considered tissue resident cells with little proliferation at steady state.Recent studies have shown that a subset of small intestinal ILC2s could leave their residing tissues,circulate and migrate to different organs,including lung,liver,mesenteric LN and spleen,upon activation.However,it remains unknown whether other ILC populations with migratory behavior exist.In this study,we find two major colon ILC2 populations with potential to migrate to the lung in response to IL-25 stimulation.One subset expresses IL-17A and resembles inflammatory ILC2s(iILC2s)but lacks CD27 expression,whereas the other expresses CD27 but not IL-17A.In addition,the IL-17A^(+)ILC2s express lower levels of CD127,CD25,and ST2 than CD27^(+)ILC2s,which express higher levels of IL-5 and IL-13.Surprisingly,we found that both colon ILC2 populations still maintained their colonic features of preferential expression of IL-17A and CD27,IL-5/IL-13,respectively.Together,our study identifies two migratory colon ILC2 subsets with unique surface markers and cytokine profiles which are critical in regulating lung and colon immunity and homeostasis. | Hongzhi Liu Liang Li Yanyun Hao Jialu Li Zhaoyuan Liu Jingjing Qi Jingjing Zhang Ningbo Wu Dandan Wu Caixia Gao Lei Chen Lei Shen Jinke Cheng Bing Su | 2023 | Science China(Life Sciences)2023，66，1： | 1 |
| 10 | Study onEconomic Development of Inner Mongolia Based onEnergy显示文摘 | Song Yuchen Liu Jinke* Meng Hai Dong | 2012 | Advanced Materials Research2012，，10： | 1 |
| 11 | Research journey of respirasome显示文摘Respirasome,as a vital part of the oxidative phosphorylation system,undertakes the task of transferring electrons from the electron donors to oxygen and produces a proton concentration gradient across the inner mitochondrial membrane through the coupled translocation of protons.Copious research has been carried out on this lynchpin of respiration.From the discovery of individual respiratory complexes to the report of the high-resolution structure of mammalian respiratory supercomplex I1III2IV1,scientists have gradually uncovered the mysterious veil of the electron transport chain(ETC).With the discovery of the mammalian respiratory mega complex I2III2IV2,a new perspective emerges in the research field of the ETC.Behind these advances glitters the light of the revolution in both theory and technology.Here,we give a short review about how scientists‘see’the structure and the mechanism of respirasome from the macroscopic scale to the atomic scale during the past decades. | Meng Wu Jinke Gu Shuai Zong Runyu Guo Tianya Liu Maojun Yang | 2020 | Protein & Cell2020，11，5： | 1 |
| 12 | UQCRFSIN assembles mitochondrial respiratory complex-Ill into an asymmetric 21-subunit dimer显示文摘 | Shuai Zong Jinke Gu Tianya Liu Runyu Guo Meng Wu Maojun Yang | 2018 | Protein & Cell2018，9，6： | 1 |
| 13 | Nanoparticle motion trajectories and deposition in an inlet channel of wall-flow diesel particulate filter显示文摘 | Yunqing Liu Jinke Gong Jun Fu Hao Cai Gang Long | 2008 | Journal of Aerosol Science2008，，4： | 1 |
| 14 | Study on economic develop- ment of Inner Mongolia based on energy显示文摘 | SONG YUCHEN LIU JINKE | 2012 | Advanced Materi- als Research2012，，6： | 1 |
| 15 | Towards Efficient Blue DelayedFluorescence Molecules by Modulating Torsion Angle Between Electron Donor and Acceptor显示文摘Constructing blue thermally activated delayedfluorescence materials for high-performance organic light-emitting diodes(OLEDs)remains challenging due to the intrinsically strong intramolecular charge transfer nature of the nearly orthogonal connection of electron donor(D)and acceptor(A),which results in long-wavelength emission.Herein,an effective delayed-fluorescence design strategy of modulating D–A torsion angles is proposed and efficient sky-blue,pure-blue,and deep-blue delayed-fluorescence molecules consisting of a xanthenone acceptor and carbazole-based donors are created by decreasing the torsion angles.They exhibit strong delayed fluorescence with high photoluminescence quantum yields of 85–94%in doped films,and their delayed-fluorescence lifetimes are elongated from 1.0 to 27.6μs as the torsion angles decrease.These molecules can function as excellent emitters in OLEDs,providing efficient electroluminescence peaking at 442 nm(CIEx,y=0.15,0.08),462 nm(CIEx,y=0.15,0.18),and 482 nm(CIEx,y=0.17,0.30)with state-of-the-art external quantum efficiencies of up to 22.2%,33.7%,and 32.1%,respectively,demonstrating the proposed molecular design for efficient blue delayed-fluorescence molecules is successful and promising. | Jinke Chen Xing Wu Hao Liu Nuoling Qiu Zhangshan Liu Dezhi Yang Dongge Ma Ben Zhong Tang Zujin Zhao | 2023 | CCS Chemistry2023，5，3： | 0 |
| 16 | Celebrity and ordinary users: A comparative study of microblog user behaviors on Sina Weibo显示文摘Purpose: This study aims to investigate and compare celebrity and ordinary users' behaviors on Sina Weibo.Design/methodology/approach: Data was collected from 12,555 ordinary users and 2,467 celebrity users on Sina Weibo. Correlation and regression analysis was performed on users' number of followings, number of followers and number of posts.Findings: The results revealed significant difference between famous and ordinary users' behaviors on Sina Weibo. We found correlation among ordinary users' number of followings, number of followers and number of posts, but for celebrity users, only their number of followings and number of posts are related with each other. For both ordinary and celebrity users, their number of followings significantly affects how many posts they publish.Research limitations: We only carried out our investigation on Sina Weibo and the findings need to be further verified on other microblogging platforms. Practical implications: This research is useful for microblogging service providers to understand different types of users and promote the continuous use of their services.Originality/value: This research delivers valuable insights into understanding of the characteristics of different types of microbloggers and the ways to increase user viscosity. | Xingjun LIU Weijun WANG Jinke WU | 2015 | Chinese Journal of Library and Information Science2015，，2： | 0 |
| 17 | SUMOylation of α-tubulin is a novel modification regulating microtubule dynamics显示文摘Microtubules (MTs) are regulated by a number of known posttranslational modifications (PTMs) on α/β-tubulin to fulfill diverse cellular functions. Here, we showed that SUMOylation is a novel PTM on α-tubulin in vivo and in vitro. The SUMOylation on α-tubulin mainly occurred at Lys 96 (K96), K166, and K304 of soluble α-tubulin and could be removed by small ubiquitin-related modifier (SUMO)-specific peptidase 1. In vitro experiments showed that tubulin SUMOylation could reduce interprotofilament interaction, promote MT catastrophe, and impede MT polymerization. In cells, mutation of the SUMOylation sites on α-tubulin reduced catastrophe frequency and increased the proportion of polymerized α-tubulin, while upregulation of SUMOylation with fusion of SUMO1 reduced α-tubulin assembly into MTs. Additionally, overexpression of SUMOylation-deficient α-tubulin attenuated the neurite extension in Neuro-2a cells. Thus, SUMOylation on α-tubulin represents a new player in the regulation of MT properties. | Wenfeng Feng Rong Liu Xuan Xie Lei Diao Nannan Gao Jinke Cheng Xu Zhang Yong Li Lan Bao | 2021 | Journal of Molecular Cell Biology2021，13，2： | 0 |
| 18 | Angle Scattering Method for Soot Concentration Measurement under Ultra-Low Emissions Condition显示文摘Aiming at the problem of soot concentration measurement under ultra-low emission conditions,a forward small angle soot concentration measurement method is proposed.Taking a typical boiler emission of 0.1μm-3.0μm bimodal distribution soot as an object,the particle scatter simulation calculation under different parameters is carried out,and the influence of detection angle and particle size on the angular scatteringmeasurement of ultra-low emission soot is analyzed.The influence of detection angle and particle size on the angular scatteringmeasurement of ultra-lowemission soot is analyzed.Preferably,thewavelength of incident light is 650 nm,and the forward detection angle parameter is 15◦for the design of forward small angle soot concentration measurement system.An experimental system for measuring soot with standard concentration is built.Experiments of particle concentration measurement of 1.0μm and 3.0μm under ultra-low emission conditions are carried out.The results show that the average deviation of soot concentration measurement is less than 0.10 mg/m3 under the condition of ultra-low emission by using 15◦of forward detection,which provides an effective way for monitoring ultra-low emission soot concentration in coal-fired power plants. | Bin Yang Xingchen Zhu Jie Deng Xiaoxu Guo Jinke Han Xiaowei Liu | 2022 | Energy Engineering2022，119，2： | 0 |
| 19 | Spatiotemporal dynamics of population density in China using nighttime light and geographic weighted regression method显示文摘The distribution and dynamic changes of regional or national population data with long time series are very important for regional planning,resource allocation,government decision-making,disaster assessment,ecological protection,and other sustainability research.However,the existing population datasets such as LandScan and WorldPop all provide data from 2000 with limited time series,while GHS-POP only utilizes land use data with limited accuracy.In view of the limited remote sensing images of long time series,it is necessary to combine existing multi-source remote sensing data for population spatialization research.In this research,we developed a nighttime light desaturation index(NTLDI).Through the cross-sensor calibration model based on an autoencoder convolutional neural network,the NTLDl was calibrated with the same period Visible Infrared Imaging Radiometer Suite Day/Night Band(VIRS-DNB)data.Then,the geographically weighted regression method is used to determine the population density of China from 1990 to 2020 based on the long time series NTL.Furthermore,the change characteristics and the driving factors of China's population spatial distribution are analyzed.The large-scale,long-term population spatialization results obtained in this study are of great significance in government planning and decision-making,disaster assessment,resource allocation,and other aspects. | Wei Guo Jinke Liu Xuesheng Zhao Wei Hou Yunxuan Zhao Yongxing Li Wenbin Sun Deqin Fan | 2023 | International Journal of Digital Earth2023，16，1： | 0 |
| 20 | Geochronology,Geochemistry,and Sr-Nd-Hf Isotopes of the Diorite Porphyrites from the Weining Beishan Area,Ningxia Hui Autonomous Region:Constraints on Their Source and Tectonic Implications显示文摘The Weining Beishan area of Ningxia Hui Autonomous Region is located at on the western edge of the Helanshan tectonic belt,which is a tectonic joint among Alxa Block,Ordos Block,and North Qilian orogenic belt.However,the tectonic evolution of this area remains unclear due to the lack of magmatic information.This paper conducted researches on geochronology,geochemistry,and Sr-Nd-Hf isotopes of the diorite porphyrites exposed in the Weining Beishan area.The zircon U-Pb dating yields two ages of 145.0±1.1 and 146.2±1.5 Ma,and the whole-rock geochemical data indicate that the diorite porphyrites are metaluminous to weakly peraluminous and high-K calc-alkaline series.The characteristics of highly initial^(87)Sr/^(86)Sr ratios(0.70816 to 0.71047),negativeε_(Nd)(t)(−8.9 to−8.4),and negativeε_(Hf)(t)(−13.8 to−21.2)indicate that the diorite porphyrites originated from partial melting of the middle-lower ancient crust related to the North China Craton.Combined with the regional geology,we suggested that partial melting was triggered by a tectonic activity of deep faults cutting through the crust under the regional stress transformation from compressing to extension during the Late Jurassic–Early Cretaceous,which is probably related to the westward subduction of the Paleo-Pacific Plate. | Anlu Liu Lianfu Hai Jinke Liu Xiaojun Zhang Haifeng Li Fengshun Zhao Guoliang Zhao Jinhe Bai | 2024 | Journal of Earth Science2024，35，2： | 0 |
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