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| 1 | Packaging and Temperature Compensation of Fiber Bragg Grating for Strain Sensing: A Survey显示文摘 | Yi KUANG Yongxing GUO Li XIONG Wenlong LIU | 2018 | Photonic Sensors2018，8，4： | 16 |
| 2 | Recent Progress in Distributed Optical Fiber Raman Photon Sensors at China Jiliang University显示文摘在在中国 Jiliang 大学(CJLU ) 的完整的分布式的纤维拉曼光子传感器的研究,生产和应用的最近的进步的简短评论被介绍。以便改进测量距离,精确性,空间分辨率,多参数大小的能力,和完整的分布式的纤维传感器系统的智力,一种新一代纤维传感器技术基于光纤维,非线性的散布熔化原则被建议。一系列新一代完整的分布式的纤维传感器被调查并且设计,它由新产生组成极端长的距离散布与一个纤维拉曼放大器综合的光子传感器的完整的分布式的纤维拉曼和瑞利,汽车修正完整的分布式的纤维拉曼光子温度传感器基于拉曼关联双来源,完整的分布式的纤维拉曼光子温度传感器基于编码的脉搏采购原料,完整的分布式的纤维拉曼光子温度传感器 | Zaixuan ZHANG | 2012 | Photonic Sensors2012，2，2： | 8 |
| 3 | Discriminated sgRNAs-Based SurroGate System Greatly Enhances the Screening Efficiency of Plant Base-Edited Cells显示文摘The development of CRISPR/Cas9-mediated base editing has made genomic modification more efficient. However, selection of genetically modified cells from millions of treated cells, especially plant cells, is still challenging. In this study, an efficient surrogate reporter system based on a defective hygromycin resistance gene was established in rice to enrich base-edited cells. After step-by-step optimization, the Discriminated sgRNAs-based SurroGate system (DisSUGs) was established by artificially differentiating the editing abilities of a wild-type single guide RNA (sgRNA) targeting the surrogate reporter gene and an enhanced sgRNA targeting endogenous sites. The DisSUGs enhanced the efficiency of screening base-edited cells by 3- to 5-fold for a PmCDA1-based cytosine-to-tyrosine base editor (PCBE), and 2.5- to 6.5-fold for an adenine base editor (ABE) at endogenous targets. These targets showed editing efficiencies of <25% in the conventional systems. The DisSUGs greatly enhanced the frequency of homozygous substitutions and expanded the activity window slightly for both a PCBE and an ABE. Analyses of the total number of single-nucleotide variants from whole-genome sequencing revealed that, compared with the no-enrichment PCBE strategy, the DisSUGs did not alter the frequency of genome-wide sgRNA-independent off-target mutations, but slightly increased the frequency of target-dependent off-target mutations. Collectively, the DisSUGs developed in this study greatly enhances the efficiency of screening plant base-edited cells and will be a useful system in future applications. | Wen Xu Yongxing Yang Ya Liu Guiting Kang Feipeng Wang Lu Li Xinxin Lv Si Zhao Shuang Yuan Jinling Song Ying Wu Feng Feng Xiaoqing He Chengwei Zhang Wei Song Jiuran Zhao Jinxiao Yang | 2020 | Molecular Plant2020，13，1： | 8 |
| 4 | Wheat powdery mildew resistance gene Pm64 derived from wild emmer (Triticum turgidum var.dicoccoides) is tightly linked in repulsion with stripe rust resistance gene Yr5显示文摘Stripe rust and powdery mildew are both devastating diseases for durum and common wheat.Pyramiding of genes conferring resistance to one or more diseases in a single cultivar is an important breeding approach to provide broader spectra of resistances in wheat improvement. A new powdery mildew resistance gene originating from wild emmer(Triticum turgidum var.dicoccoides) backcrossed into common wheat(T. aestivum) line WE35 was identified. It conferred an intermediate level of resistance to Blumeria graminis f. sp. tritici isolate E09 at the seedling stage and a high level of resistance at the adult plant stage. Genetic analysis showed that the powdery mildew resistance in WE35 was controlled by a dominant gene designated Pm64. Bulked segregant analysis(BSA) and molecular mapping indicated that Pm64 was located in chromosome bin 2 BL4-0.50–0.89. Polymorphic markers were developed from the corresponding genomic regions of Chinese Spring wheat and wild emmer accession Zavitan to delimit Pm64 to a 0.55 cM genetic interval between markers WGGBH1364 and WGGBH612, corresponding to a 15 Mb genomic region on Chinese Spring and Zavitan 2 BL, respectively. The genetic linkage map of Pm64 is critical for fine mapping and cloning. Pm64 was completely linked in repulsion with stripe rust resistance gene Yr5. Analysis of a larger segregating population might identify a recombinant line with both genes as a valuable resource in breeding for resistance to powdery mildew and stripe rust. | Deyun Zhang Keyu Zhu Lingli Dong Yong Liang Genqiao Li Tilin Fang Guanghao Guo Qiuhong Wu Jingzhong Xie Yongxing Chen Ping Lu Miaomiao Li Huaizhi Zhang Zhenzhong Wang Yan Zhang Qixin Sun Zhiyong Liu | 2019 | The Crop Journal2019，7，6： | 8 |
| 5 | Mapping stripe rust resistance genes by BSR-Seq:YrMM58 and YrHY1 on chromosome 2AS in Chinese wheat lines Mengmai 58 and Huaiyang 1 are Yr17显示文摘Stripe rust(yellow rust), caused by Puccinia striiformis f. sp. tritici(PST),is one of the most devastating fungal diseases in common wheat(Triticum aestivum L.) in China and worldwide. Resistance breeding is the most effective strategy to control diseases in crop plants. Chinese wheat lines Mengmai 58 and Huaiyang 1 are highly resistant to PST race CYR34(V26) at the adult plant stage. To genetically map the underlying resistance genes we developed segregating populations by crossing Mengmai 58 and Huaiyang 1 with the susceptible cultivar Nongda 399. The stripe rust resistances in Mengmai 58 and Huaiyang 1 were both controlled by single dominant genes, provisionally designated YrMM58 and YrHY1, respectively. Bulked segregant RNA-Seq(BSR-Seq) analysis showed that YrMM58 and YrHY1 were located in the same distal ~16 Mb region on chromosome 2 AS.Comparative genomics analysis with the physical map of Aegilops tauschii proved useful for developing additional markers to saturate the genetic linkage map. YrMM58 and YrHY1 were mapped to the distal end of chromosome arm 2 AS, with the closest marker WGGB148 being 7.7 cM and 3.8 cM from the resistance gene, which was considered to be Yr17. These markers can be used in marker-assisted selection. | Yong Wang Huaizhi Zhang Jingzhong Xie Bingmin Guo Yongxing Chen Huaiyu Zhang Ping Lu Qiuhong Wu Miaomiao Li Deyun Zhang Guanghao Guo Jian Yang Panpan Zhang Yan Zhang Xicheng Wang Hong Zhao Tingjie Cao Zhiyong Liu | 2018 | The Crop Journal2018，6，1： | 5 |
| 6 | Design of an Enhanced Sensitivity FBG Strain Sensor and Application in Highway Bridge Engineering显示文摘紧张传感器被给,并且而且高取得资格,拉紧传感器的提高的敏感纤维栅栏(FBG ) 的理论设计方法被开发并且制作,谁的察觉到性质对实际应用程序好。有圆柱的壳封装的紧张传感器包含了三管状的结构,由于不平的表面结构,在紧张集中的区域,改进敏感。它能完成埋入紧张测量和表面测量并且有容易的安装的优点。好协议在大小和理论模拟结果之间被获得。在每刻度测试以后, 24 个 FBG 紧张传感器和六个 FBG 温度赔偿传感器在 Yongtaiwen 高速公路在 Diaoshuiyan 桥牌的盒子 girder 的下面上被安装了。最后,我们为高速公路桥建立了一个长期的结构健康系统。 | Litong LI Dongsheng ZHANG Hui LIU Yongxing GUO Fangdong ZHU | 2014 | Photonic Sensors2014，4，2： | 4 |
| 7 | Mapping a leaf senescence gene els1 by BSR-Seq in common wheat显示文摘Leaf senescence is normally the last stage of plant development. Early senescence of functional leaves significantly reduces the photosynthetic time and efficiency, seriously affecting grain yield and quality in wheat. Discovering genes responsible for early leaf senescence(els) are necessary for developing novel germplasms and cultivars with delayed leaf-senescence through molecular manipulation and marker assisted selection. In this study, we identified an early leaf senescence line M114 in a derivative of a wheat breeding population. Genetic analysis indicated that early leaf senescence in M114 is controlled by a single recessive gene, provisionally designated els1. By applying bulked segregant analysis and RNA-Seq(BSR-Seq), seven polymorphic markers linked to els1 were developed and the gene was located on chromosome arm 2 BS in a 1.5 c M genetic interval between markers WGGB303 and WGGB305. A co-segregating marker, WGGB302, provide a starting point for fine mapping and map-based cloning of els1. | Miaomiao Li Beibei Li Guanghao Guo Yongxing Chen Jingzhong Xie Ping Lu Qiuhong Wu Deyun Zhang Huaizhi Zhang Jian Yang Panpan Zhang Yan Zhang Zhiyong Liu | 2018 | The Crop Journal2018，6，3： | 3 |
| 8 | The Significance of CXCR4 Expression for the Prediction of Lymph Node Metastasis in Breast Cancer Patients显示文摘OBJECTIVE The chemokine receptor(CXCR4)CXC chemokine receptor 4)plays an important role in cancer metastasis.We therefore studied differential expression of the CXCR4,as well as that of the biomarker HER2,so as to evaluate whether these biomarkers can be used to predict axillary lymph node metastasis in breast cancer patients. METHODS Immunohistochemistry was used to evaluate the CXCR4 and HER2 expressions and to examine the paraffin sections of the breast cancers at various stages.Positive lymph node expression was found in 80 of the cases,and in 7 there was negative expression. RESULTS Compared to the cases with negative lymph nodes, there was a high expression of CXCR4(26.3% vs.14.3%,P=0.013), and an over-expression of HER2(28.8% vs.14.3%,P=0.011). Moreover,there was a direct correlation between the CXCR4 and HER2 expressions and the tumor staging(P=0.000)and lymph node metastasis(P=0.032).When the two biomarkers,i.e.CXCR4 and HER2,were concurrently labeled,a high expression of one of the biomarkers could be seen in the cases with positive lymph nodes(51.3% vs.28.6%,P<0.003). CONCLUSION The chemokine receptor,CXCR4,is a new-type biomarker in predicting axillary lymph-node metastasis in breast cancers.Compared with the other markers,such as HER2 etc., assessment of CXCR4 can improve the prediction of the presence and extent of lymph node involvement. | Yongxing Ding Chenghua Li Qingling Yang Changjie Chen Zenong Cheng | 2008 | Chinese Journal of Clinical Oncology2008，5，2： | 3 |
| 9 | High efficient catalytic oxidation of 5-hydroxymethylfurfural into 2,5-furandicarboxylic acid under benign conditions with nitrogen-doped graphene encapsulated Cu nanoparticles显示文摘Selective oxidation of 5-hydroxymethylfurfual(HMF) to 2,5-furandicarboxylic acid(FDCA) as a bioplastics monomer is efficiently promoted by a simple system without noble-metal and base additives. In this work, graphene oxide(GO) was first synthesised by an electrochemical method with flexible graphite paper(FGP) as start carbon material, then, nitrogen-doped graphene(NG) layers encapsulated Cu nanoparticles(NPs) was prepared by one-step thermal treatment of GO supported Cu2+ in flowing NH3 atmosphere. Compared with NG supported Cu NPs prepared by the traditional impregnation method, enhanced catalytic activity was achieved over Cu/NG and an FDCA yield of 95.2% was achieved under mild reaction conditions with tert-butylhydroperoxide(t-BuOOH) as the oxidant. Control experiments with different catalysts and different addition procedure of t-BuOOH showed the yield of HMF and various intermediates during reaction. From the changing of intermediates concentrations and reaction rates, a reaction pathway through HMF-DFF-FFCA-FDCA was proposed. This work gives a more convenient, more green,more economical and effective method in encapsulated metal NPs preparation and high selectivity in HMF oxidation to FDCA under mild conditions. | Chaoxin Yang Xiao Li Zhenzhou Zhang Bohan Lv Jiachun Li Zhenjian Liu Wanzhen Zhu Furong Tao Guangqiang Lv Yongxing Yang | 2020 | Journal of Energy Chemistry2020，29，11： | 3 |
| 10 | Rapid Acclimation of Methanogenic Granular Sludge into Autotrophic Partial Denitrification Granules显示文摘Rapid formation of autotrophic partial denitrification(APD)granules is of practical interest to start up an expanded granular sludge bed reactor for wastewater treatment.This study demonstrates that methanogenic granules can be easily acclimated into autotrophic partial denitrification granules in one day,with the ability to remove 82%of 2.7 kg-S/(m^3·d)sulfide into S^0 and to convert 97%of 0.9 kg-N/(m^3·d)nitrate into nitrite,which can provide a promising feedstock for anaerobic ammonia oxidation process.Arcobacter sp.is essential for S^0 accumulation.Under high loadings,the abundance of Arcobacter sp.decreased,while on the contrary the abundance of unclassified_p_Firmicutes increased,leading to the deterioration of autotrophic partial denitrification performance.The granules performance could be recovered by adopting the strategies of properly reducing the influent loadings. | Liu Chunshuang Li Xuechen Zhang Xiaofei Bai Xue Guo Yadong Wang Yongxing Zhao Chaocheng | 2019 | China Petroleum Processing & Petrochemical Technology2019，21，3： | 2 |
| 11 | miR-23a/b suppress cGAS-mediated innate and autoimmunity显示文摘Cyclic GMP-AMP synthase(cGAS),a key sensor of intracellular DNA,is essential for eliciting innate immunity against infection,whereas aberrant activation of cGAS by endogenous DNA promotes severe autoimmune diseases.However,it is largely unknown how cGAS expression is regulated during pathogen infection and autoimmunity.Here,we report that during herpes simplex virus type 1(HSV-1)infection,two microRNAs(miR-23a and miR-23b)whose levels significantly decrease due to their interaction with the lncRNA Oasl2-209 directly regulate the expression of cGAS.Overexpression of miR-23a/b markedly dampens cytosolic DNA-induced innate immune responses,whereas inhibition of miR-23a/b enhances these responses.Mice treated with miR-23a/b agomirs exhibit increased susceptibility to HSV-1 infection.Moreover,cGAS is significantly upregulated in the Trex1^(−/−)mouse autoimmune disease model.Administration of miR-23a/b blunts self DNA-induced autoinflammatory responses in Trex1^(−/−)mice.Collectively,our study not only reveals a novel regulatory mechanism of cGAS expression by miRNAs but also identifies a potential therapy for cGAS-related autoimmune diseases. | Qiuya Yu Lei Chu Yongxing Li Quanyi Wang Juanjuan Zhu Chen Wang Shufang Cui | 2021 | Cellular & Molecular Immunology2021，18，5： | 2 |
| 12 | On normal families of meromorphic functions显示文摘 | LI Yuntong GU Yongxing | 2009 | J Math Anal Appl2009，354，2： | 1 |
| 13 | Novel Structured Dynamic Mesh Generation for CFD Analysis of Scroll Compressors 显示文摘 | 8] WANG Jun SONG Yongxing LI Qiang | 2015 | Proceedings of the Institution of Mechanical Engineers Part A: Journal of Power and Energy2015，229，10： | 1 |
| 14 | A novel mechanism for endothelial progenitor cells homing: The SDF-1/CXCR4–Rac pathway may regulate endothelial progenitor cells homing through cellular polarization显示文摘 | Li Shen Yongxing Gao Juying Qian Aijun Sun Junbo Ge | 2010 | Medical Hypotheses2010，，2： | 1 |
| 15 | Ultra-deep desulfurization of diesel by selective oxidation with [C 18 H 37 N(CH 3 ) 3 ] 4 [H 2 NaPW 10 O 36 ] catalyst assembled in emulsion droplets显示文摘 | Hongying Lü Jinbo Gao Zongxuan Jiang Fei Jing Yongxing Yang Gang Wang Can Li | 2006 | Journal of Catalysis2006，，2： | 1 |
| 16 | Deep desulfurization from fuel oil via selective oxidation using an amphiphilic peroxotungsten catalyst assembled in emulsion droplets显示文摘 | Jinbo Gao Shouguo Wang Zongxuan Jiang Hongying Lu Yongxing Yang Fei Jing Can Li | 2006 | Journal of Molecular Catalysis A Chemical2006，，1： | 1 |
| 17 | Selective Oxidations on Recoverable Catalysts Assembled in Emulsions显示文摘 | Can Li Jinbo Gao Zongxuan Jiang Shouguo Wang Hongying Lu Yongxing Yang Fei Jing | 2005 | Topics in Catalysis (-)2005，，12： | 1 |
| 18 | Dibenzothiophene hydrodesulfurization activity and surface sites of silica-supported MoP, Ni 2 P, and Ni<ce:glyph name='sbnd'/>Mo<ce:glyph name='sbnd'/>P catalysts显示文摘 | Fuxia Sun Weicheng Wu Zili Wu Jun Guo Zhaobin Wei Yongxing Yang Zongxuan Jiang Fuping Tian Can Li | 2004 | Journal of Catalysis2004，，2： | 1 |
| 19 | Ultra-deep desulfurization of diesel by selective oxidation with [C 18 H 37 N(CH 3 ) 3 ] 4 [H 2 NaPW 10 O 36 ] catalyst assembled in emulsion droplets显示文摘 | Hongying Lü Jinbo Gao Zongxuan Jiang Fei Jing Yongxing Yang Gang Wang Can Li | 2006 | Journal of Catalysis2006，，2： | 1 |
| 20 | Developing an efficient and visible prime editing system to restore tobacco 8-hydroxy-copalyl diphosphate gene for labdane diterpene Z-abienol biosynthesis显示文摘Prime editing(PE)is a versatile CRISPR-Cas based precise genome-editing platform widely used to introduce a range of possible base conversions in various organisms.However,no PE systems have been shown to induce heritable mutations in tobacco,nor in any other dicot.In this study,we generated an efficient PE system in tobacco that not only introduced heritable mutations,but also enabled anthocyanin-based reporter selection of transgene-free T_(1) plants.This system was used to confer Zabienol biosynthesis in the allotetraploid tobacco cultivar HHDJY by restoring a G>T conversion in the NtCPS2 gene.High levels of Z-abienol were detected in the leaves of homozygous T_(1) plants at two weeks after topping.This study describes an advance in PE systems and expands genome-editing toolbox in tobacco,even in dicots,for use in basic research and molecular breeding.And restoring biosynthesis of Z-abienol in tobacco might provide an efficient way to obtain Z-abienol in plants. | Jianduo Zhang Lu Zhang Chengwei Zhang Yongxing Yang Huayin Liu Lu Li Shengxue Zhang Xianggan Li Xinxiang Liu Ya Liu Jin Wang Guangyu Yang Qingyou Xia Weiguang Wang Jinxiao Yang | 2023 | Science China(Life Sciences)2023，66，12： | 1 |
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