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| 1 | Atomic-Scale Layer-by-Layer Deposition of Fe SiAl@ZnO@Al_(2)O_(3) Hybrid with Threshold Anti-Corrosion and Ultra-High Microwave Absorption Properties in Low-Frequency Bands显示文摘Developing highly efficient magnetic microwave absorb-ers(MAs)is crucial,and yet challenging for anti-corrosion properties in extremely humid and salt-induced foggy environments.Herein,a dual-oxide shell of ZnO/Al_(2)O_(3) as a robust barrier to FeSiAl core is introduced to mitigate corrosion resistance.The FeSiAl@ZnO@Al_(2)O_(3) layer by layer hybrid structure is realized with atomic-scale precision through the atomic layer deposition technique.Owing to the unique hybrid structure,the FeSiAl@ZnO@Al_(2)O_(3) exhibits record-high micro-wave absorbing performance in low-frequency bands covering L and S bands with a minimum reflection loss(RLmin)of-50.6 dB at 3.4 GHz.Compared with pure FeSiAl(RLmin of-13.5 dB,a bandwidth of 0.5 GHz),the RLmin value and effective bandwidth of this designed novel absorber increased up to~3.7 and~3 times,respectively.Fur-thermore,the inert ceramic dual-shells have improved 9.0 times the anti-corrosion property of FeSiAl core by multistage barriers towards corrosive medium and obstruction of the electric circuit.This is attributed to the large charge transfer resistance,increased impedance modulus|Z|0.01 Hz,and frequency time constant of FeSiAl@ZnO@Al_(2)O_(3).The research demonstrates a promising platform toward the design of next-generation MAs with improved anti-corrosion properties. | Wei Tian Jinyao Li Yifan Liu Rashad Ali Yang Guo Longjiang Deng Nasir Mahmood Xian Jian | 2021 | Nano-Micro Letters2021，13，10： | 6 |
| 2 | Faulting, magmatism and crustal oceanization of the Okinawa Trough显示文摘The paper focuses on the characteristics of faulting and magmatism of the Okinawa Trough and the relation between them. En-echelon grabens are ranked oblique to the continental shelf edge uplift, and the Longwang uplift, the rifting block ridge in the northern segment and the 'Mianhua uplift' in the southern segment have possibly preserved characteristics of volcanism and magmatism occurring with those rifting phases. The clockwise rotation of the southern Ryukyu Islands, driven by collision between Luzon and Taiwan, has played a key role in the crustal oceanization, enhancing the crustal extension of the southern segment and inducing volcanic magmatism in those grabens, among which the Yaeyama graben is a typical example of the presence of oceanic crust. Faulting and magmatism were mainly migrating towards the island arc asymmetrically. The crustal oceanization of the Okinawa Trough is diffcultly interpreted by the linear magnetic anomaly model, which is fit for the symmetric spreading of the mid-oceanic ridges. | GAO Jinyao ZHANG Tao FANG Yinxia YANG Chuanguo MEI Sai | 2009 | Acta Oceanologica Sinica2009，28，3： | 5 |
| 3 | Nuclear Aurora kinase A switches m^(6)A reader YTHDC1 to enhance an oncogenic RNA splicing of tumor suppressor RBM4显示文摘Aberrant RNA splicing produces alternative isoforms of genes to facilitate tumor progression,yet how this process is regulated by oncogenic signal remains largely unknown.Here,we unveil that non-canonical activation of nuclear AURKA promotes an oncogenic RNA splicing of tumor suppressor RBM4 directed by m^(6)A reader YTHDC1 in lung cancer.Nuclear translocation of AURKA is a prerequisite for RNA aberrant splicing,specifically triggering RBM4 splicing from the full isoform(RBM4-FL)to the short isoform(RBM4-S)in a kinase-independent manner. | SiSi Li YangFan Qi JiaChuan Yu YuChao Hao Bin He MengJuan Zhang ZhenWei Dai TongHui Jiang SuYi Li Fang Huang Ning Chen Jing Wang MengYing Yang DaPeng Liang Fan An JinYao Zhao WenJun Fan YuJia Pan ZiQian Deng YuanYuan Luo Tao Guo Fei Peng ZhiJie Hou ChunLi Wang FeiMeng Zheng LingZhi Xu Jie Xu QingPing Wen BiLian Jin Yang Wang Quentin Liu | 2022 | Signal Transduction and Targeted Therapy2022，7，5： | 4 |
| 4 | Mantle melting factors and amagmatic crustal accretion of the Gakkel ridge, Arctic Ocean显示文摘Spreading rate is a primary factor of mantle melting and tectonic behavior of the global mid-ocean ridges. The spreading rate of the Gakkel ridge decreases gradually from west to east. However, the Gakkel ridge can be divided into four thick-and-thin zones with varying crustal thicknesses along ridge axis. This phenomenon indicates that mantle melting of the Gakkel ridge is not a simple function of spreading rate. Mantle temperature, water content,mantle composition, and other factors are important in crustal accretion processes. Based on gravity-derived crustal thickness and wet melting model, we estimate that the mantle potential temperatures of the four zones are1 270, 1 220, 1 280, and 1 280°C(assuming that mantle water content equals to global average value), with corresponding mantle water contents of 210, 0, 340, and 280 mg/kg(assuming that mantle potential temperature is 1 260°C), respectivly. The western thinned crust zone is best modeled with low mantle temperature, whereas the other zones are mainly controlled by the enhanced conduction caused by the slower spreading rate. Along the Gakkel ridge, the crustal thickness is consistent with rock samples types. Predominated serpentinized peridotite and basalt are found in the area with crustal thickness <1.5 km and >2.5 km, respectively. The rock samples are including from basalt to peridotite in the area with crustal thickness between 1.5 and 2.5 km. Based on this consistency, the traditional magmatic accretion zone accounted for only 44% and amagmatic accretion accounted for 29% of the Gakkel ridge. The amagmatic accretion is a significant characteristic of the ultra-slow spreading ridge. | ZHANG Tao GAO Jinyao CHEN Mei YANG Chunguo SHEN Zhongyan ZHOU Zhiyuan WU Zhaocai SUN Yunfan | 2015 | Acta Oceanologica Sinica2015，34，6： | 3 |
| 5 | Aberrant alternative splicing in breast cancer显示文摘Alternative splicing is critical for human gene expression regulation,which plays a determined role in expanding the diversity of functional proteins.Importantly,alternative splicing is a hallmark of cancer and a potential target for cancer therapeutics.Based on the statistical data,breast cancer is one of the top leading causes of cancer-related deaths in women worldwide.Strikingly,alternative splicing is closely associated with breast cancer development.Here,we seek to provide a general review of the relationship between alternative splicing and breast cancer.We introduce the process of alternative splicing and its regulatory role in cancers.In addition,we highlight the functions of aberrant alternative splicing and mutations of splicing factors in breast cancer progression.Moreover,we discuss the role of alternative splicing in cancer drug resistance and the potential of being targets for cancer therapeutics. | Quan Yang Jinyao Zhao Wenjing Zhang Dan Chen Yang Wang | 2019 | Journal of Molecular Cell Biology2019，11，10： | 3 |
| 6 | SRSF1 inhibits autophagy through regulating Bcl-x splicing and interacting with PIK3C3 in lung cancer显示文摘Alternative splicing is a critical process to generate protein diversity.However,whether and how alternative splicing regulates autophagy remains largely elusive.Here we systematically identify the splicing factor SRSF1 as an autophagy suppressor.Specifically,SRSF1 inhibits autophagosome formation by reducing the accumulation of LC3-ⅡI and numbers of autophagosomes in different cell lines.Mechanistically,SRSF1 promotes the splicing of the long isoform of Bcl-x that interacts with Beclinl,thereby dissociating the Beclin1-PIK3C3 complex.In addition,SRSF1 also directly interacts with PIK3C3 to disrupt the interaction between Beclinl and PIK3C3.Consequently,the decrease of SRSF1 stabilizes the Beclinl and PIK3C3 complex and activates autophagy.Interestingly,SRSF1 can be degraded by starvation-and oxidative stresses-induced autophagy through interacting with LC3-Ⅱ,whereas reduced SRSF1 further promotes autophagy.This positive feedback is critical to inhibiting Gefitinib-resistant cancer cell progression both in vitro and in vivo.Consistently,the expression level of SRSF1 is inversely correlated to LC3 level in clinical cancer samples.Our study not only provides mechanistic insights of alternative splicing in autophagy regulation but also discovers a new regulatory role of SRSF1 in tumorigenesis,thereby offering a novel avenue for potential cancer therapeutics. | Yuesheng Lv Wenjing Zhang Jinyao Zhao Bing Sun Yangfan Qi Haoyu Ji Chaoqun Chen Jinrui Zhang Junxiu Sheng Taishu Wang Daniel Dominguez Han Liu Quentin Liu Songshu Meng Xiaoling Li Yang Wang | 2021 | Signal Transduction and Targeted Therapy2021，6，4： | 2 |
| 7 | Alloy-Electrode-Assisted High-Performance Enhancement-Type Neodymium-Doped Indium-Zinc-Oxide Thin-Film Transistors on Polyimide Flexible Substrate显示文摘Flexible thin-film transistors with high current-driven capability are of great significance for the next-generation new display technology.The effect of a Cu-Cr-Zr(CCZ)copper alloy source/drain(S/D)electrode on flexible amorphous neodymiumdoped indium-zinc-oxide thin-film transistors(NdIZO-TFTs)was investigated.Compared with pure copper(Cu)and aluminum(Al)S/D electrodes,the CCZ S/D electrode changes the TFT working mode from depletion mode to enhancement mode,which is ascribed to the alloy-assisted interface layer besides work function matching.X-ray photoelectron spectroscopy(XPS)depth profile analysis was conducted to examine the chemical states of the contact interface,and the result suggested that chromium(Cr)oxide and zirconium(Zr)oxide aggregate at the interface between the S/D electrode and the active layer,acting as a potential barrier against residual free electron carriers.The optimal NdIZO-TFT exhibited a desired performance with a saturation mobility(μsat)of 40.3 cm^(2)·V-1·s^(-1),an Ion/Ioff ratio of 1:24×10^(8),a subthreshold swing(SS)value of 0.12 V·decade^(-1),and a threshold voltage(Vth)of 0.83 V.This work is anticipated to provide a novel approach to the realization of highperformance flexible NdIZO-TFTs working in enhancement mode. | Kuankuan Lu Rihui Yao Wei Xu Honglong Ning Xu Zhang Guanguang Zhang Yilin Li Jinyao Zhong Yuexin Yang Junbiao Peng | 2021 | Research2021，，1： | 1 |
| 8 | Effects of chlorinated polypropylene on the hydrogen-bond and electric property of polypropylene/chlorinated polypropylene/polyaniline composites: FTIR analysis 显示文摘 | YANG Lin CHEN Jinyao LI Huilin | 2009 | Polym Eng Sci2009，49，： | 1 |
| 9 | Estimation of annual variation of water vapor in the Arctic Ocean between 80°–87°N using shipborne GPS data based on kinematic precise point positioning显示文摘The measurement of atmospheric water vapor(WV) content and variability is important for meteorological and climatological research. A technique for the remote sensing of atmospheric WV content using ground-based Global Positioning System(GPS) has become available, which can routinely achieve accuracies for integrated WV content of 1–2 kg/m2. Some experimental work has shown that the accuracy of WV measurements from a moving platform is comparable to that of(static) land-based receivers. Extending this technique into the marine environment on a moving platform would be greatly beneficial for many aspects of meteorological research, such as the calibration of satellite data, investigation of the air-sea interface, as well as forecasting and climatological studies. In this study, kinematic precise point positioning has been developed to investigate WV in the Arctic Ocean(80°–87°N) and annual variations are obtained for 2008 and 2012 that are identical to those related to the enhanced greenhouse effect. | LUO Xiaowen ZHANG Tao GAO Jinyao YANG Chunguo WU Zaocai | 2015 | Acta Oceanologica Sinica2015，34，6： | 1 |
| 10 | Genetic variation analysis of reemerging porcine epidemic diarrhea virus prevailing in central China from 2010 to 2011显示文摘 | Xia Yang Jinyao Huo Lu Chen | 2013 | Virus Genes2013，46，： | 1 |
| 11 | Progress in Antarctic marine geophysical research by the Chinese Polar Program显示文摘Marine geophysical survey by the Chinese National Antarctic Research Expedition(CHINARE) began with the first science expedition in 1984/1985, although only four cruises were performed in the vicinity of the Antarctic Peninsula between then and 1991/1992. After a 20 year hiatus, Antarctic marine geophysical research was relaunched by the Chinese Polar Environmental Comprehensive Investigation and Assessment Programs(known simply as the Chinese Polar Program) in 2011/2012. Integrated geophysical surveys have been carried out annually since, in Prydz Bay and the Ross Sea. During the last 5 years, we have acquired about 5500 km of bathymetric, gravimetric, and magnetic lines; more than 1800 km of seismic reflection lines; and data from several heat flow and Ocean Bottom Seismometer(OBS) stations. This work has deepened understandings of geophysical features and their implications for geological tectonics and glacial history in Antarctica and its surrounding seas. Compiled Antarctic Bouguer and Airy isostatic gravity anomalies show different features of tectonics between the East Antarctic stability and West Antarctic activity. Calculated magnetic anomalies, heat flow anomalies and lithospheric anisotropy offshore of Prydz Bay may imply high heat capacity of mantle shielded by the continental shelf lithosphere, but high heat dissipation of mantle due to the Cretaceous breakup of Gondwana along the continent and ocean transition(COT), where large sediment ridges would be brought about by the Oligocene ice sheet retreat and would enlarge free-air gravity anomalies. In the western Ross Sea, CHINARE seismic profiles indicate northern termination of the Terror Rift and deposition time of the grounding zone wedge in the northern JOIDES Basin. | GAO Jinyao SHEN Zhongyan YANG Chunguo WANG Wei JI Fei WU Zhaocai NIU Xiongwei DING Weifeng LI Dongxu ZHANG Qiao | 2017 | Advances in Polar Science2017，28，4： | 1 |
| 12 | Glacial bedforms in the Northwind Abyssal Plain,Chukchi Borderland显示文摘A series of sub-parallel linear glacial scours are identified on the crest of the Baoshi Seamount in the Northwind Abyssal Plain by compiling new multibeam data acquired during the 9 th Chinese Arctic Research Expedition(CHINARE-Arc9)in 2018 and previously published data.The new data reveal scours that developed at water depths of 850–1030 m with an orientation of about 75°/255°.The maximum water depth occurs in the southernmost scour and is deeper than that from previous investigations,which showed a maximum scouring depth of about 900 m on the seamount.The topographic and geomorphological characteristics suggest that these scours resulted from erosion by the ice shelf extending from the Chukchi margin and/or Laurentide Ice Sheet that grounded on the crest of the seamount and moved in a NE–SW direction.Other possibilities of their genesis include armadas of large icebergs/multi-keel icebergs calved from the Chukchi Shelf or the Laurentide Ice Sheet.The new data provide new constraints for assessing the extent and volume of the ice sheet in the Chukchi area during glacial maxima. | Zhongyan Shen Tao Zhang Jinyao Gao Chunguo Yang Qingsheng Guan | 2021 | Acta Oceanologica Sinica2021，40，5： | 1 |
| 13 | Effect of Lycopene Sup- plementation on Oxidative Stress: An Exploratory Systematic Review and Meta-Analysis of Randomized Controlled Trials 显示文摘 | Jinyao Chen Yang Song and Lishi Zhang | 2013 | Journal of Medicinal Food2013，16，5： | 1 |
| 14 | Molecular cloning, expression, and characterization of a Sophora alopecuroides lectin from Escherichia coli显示文摘Sophora alopecuroides lectin (柳安) 从种子被孤立并且证实了有抗真菌并且 antitumor 活动,并且一会儿自然 lectin 的准备是拖累的,费时间,并且收益为进一步的分析是相对低的。在这研究, lectin,修正地点,和第二等的结构的信号肽被分析,并且柳安的三维的结构被建模。柳安的基因被反向的抄写聚合酶链反应放大,并且克隆进 pET-30a 向量并且由 isopropyl-beta-d-thiogalactopyranoside 的正式就职在 Escherichia coli BL21 (DE3 ) 表示了。完全, recombinant 柳安(rSAL ) 的 400 mg 通过 Ni-NTA agarose 列从细菌的文化的 1 l 被净化,纯净到达了 95% 。recombinant 蛋白质被西方的污点进一步用 rSAL 特定的抗体证实。生物活动分析结果显示出只绑在 d 半乳糖并且举办了通用 hemagglutinating 活动到人的 A, B, O,和 AB 的那 rSAL,并且兔子和老鼠红血球。rSAL 也禁止了真菌,癌症细胞的增长,和 HIV-I 反向的 transcriptase 活动的生长。在结论,这研究显示 rSAL 能在原核生物的表示系统在大数量被生产, recombinant 蛋白质仍然保留各种各样的生物活动,它将以可能的戏剧性地减少的成本做柳安 recombinant 蛋白质的大规模生产。 | Yang Li Tingting Li Jinyao Li Dongliang Liu Jie Yang Jianhua Yang Fuchun Zhang Surong Sun | 2014 | Acta Biochimica et Biophysica Sinica2014，46，9： | 0 |
| 15 | Niao Chao Hill——Study of supporting techniques for China’s first international undersea feature name显示文摘In recent years, Sub-Committee on Undersea Feature Names (SCUFN) has been conducting deliberations on naming undersea features that are entirely or mainly (more than 50%) outside the external limits of the territorial sea,adhering to the principles of not involving sovereignty dispute between countries. | TAO ChunHui LI ShouJun SONG ChengBing CHENG YongShou YANG ChunGuo HE YongHua ZHOU Yang DENG XianMing GAO JinYao QIU Lei | 2012 | Science China Earth Sciences2012，55，10： | 0 |
| 16 | Potassium ion pre‑intercalated MnO_(2)for aqueous multivalent ion batteries显示文摘Manganese dioxide(MnO_(2)),as a cathode material for multivalent ion(such as Mg^(2+)and Al^(3+))storage,is investigated due to its high initial capacity.However,during multivalent ion insertion/extraction,the crystal structure of MnO_(2)partially collapses,leading to fast capacity decay in few charge/discharge cycles.Here,through pre-intercalating potassium-ion(K+)intoδ-MnO_(2),we synthesize a potassium ion pre-intercalated MnO_(2),K_(0.21)MnO_(2)·0.31H_(2)O(KMO),as a reliable cathode material for multivalent ion batteries.The as-prepared KMO exhibits a high reversible capacity of 185 mAh/g at 1 A/g,with considerable rate performance and improved cycling stability in 1 mol/L MgSO_(4)electrolyte.In addition,we observe that aluminum-ion(Al^(3+))can also insert into a KMO cathode.This work provides a valid method for modifcation of manganesebased oxides for aqueous multivalent ion batteries. | Zikang Xu Ruiqi Ren Hang Ren Jingyuan Zhang Jinyao Yang Jiawen Qiu Yizhou Zhang Guoyin Zhu Liang Huang Shengyang Dong | 2023 | Frontiers of Optoelectronics2023，16，4： | 0 |
| 17 | Bedrock samples from the Chukchi Borderland, Arctic Ocean——First Chinese dredge in the polar regions显示文摘The Chukchi Borderland is a relict continental block in the Arctic Ocean.Its origin and tectonic processes are of great significance for understanding the formation model of the Amerasia Basin and the configurations of the Mesozoic Arctic regions.Due to the harsh environment and rare geological and geophysical data,the evolution of the Chukchi Borderland is still unclear(e.g.,Grantz et al.,1998,2011).We conducted two rock dredges and a multibeam full coverage survey of 830 km2 in the Northwind Abyssal Plain of the Chukchi Borderland during the Chinese ninth Arctic scientific expedition in 2018.This is the first rock dredge survey of China in the polar regions with floating ice,and is just after the HLY0905 dredge at the Northwind Abyssal Plain in 2009(Mayer and Armstrong,2011).The retrieved samples will provide new information for understanding the origin and tectonic evolution of the Chukchi Borderland. | Tao Zhang Yanhui Dong Chunguo Yang Qingsheng Guan Jinyao Gao | 2019 | Acta Oceanologica Sinica2019，38，11： | 0 |
| 18 | Large-scale synthesis of fluorine-free carbonyl iron-organic silicon hydrophobic absorbers with long term corrosion protection property显示文摘Environmentally-friendly magnetic metallic absorbers with high-performing antioxidant property,thermal stability,and anticorrosion capability have attracted great attention in real-world applications.A surface modification technology of magnetic metallic absorbers with dense and inert materials has been an effective strategy to solve the aforesaid problem.Herein,fluorinefree core–shell carbonyl iron-organic silicon absorbers(CI@SiO_(2)/1,1,1,3,3,3-hexamethyl disilazane(HMDS))were fabricated via a facile one-pot synthesis using tetraethyl orthosilicate(TEOS)and HMDS as the precursor of protective layer(SiO_(2)/HMDS),and CI@SiO_(2)/HMDS hybrid reveals its long-term corrosion resistance and excellent microwave absorption performance with a minimum reflection loss value of−44.3 dB and an effective absorption bandwidth of 5.3 GHz at a thin thickness of 2.0 mm after immersion in 5.0 wt.%NaCl acidic solutions for 2,160 h.Meanwhile,CI@SiO_(2)/HMDS hybrid can still achieve the maximum radar cross-sectional(RCS)reduction values about 16.5 dB·m^(2) at the detectionθof 0°.The exceptional microwave absorption performance and structural stability are largely due to the extraordinary wave-transparent property and shielding ability against corrosive medium of SiO_(2)/HMDS hydrophobic protective layer with a contact angle of 132.5°.The research paves the way for the large-scale and batch production of high-performance magnetic metallic absorbers and increases their survivability and reliability in the harsh environments. | Wei Tian Jinyao Li Yifan Liu Longjiang Deng Yang Guo Xian Jian | 2022 | Nano Research2022，15，10： | 0 |
| 19 | Ebola Spread Model显示文摘 | Jinyao YANG | 2015 | International Journal of Technology Management2015，，4： | 0 |
| 20 | RBM4 dictates ESCC cell fate switch from cellular senescence to glutamine-addiction survival through inhibiting LKB1-AMPK-axis显示文摘Cellular senescence provides a protective barrier against tumorigenesis in precancerous or normal tissues upon distinct stressors.However,the detailed mechanisms by which tumor cells evade premature senescence to malignant progression remain largely elusive.Here we reported that RBM4 adversely impacted cellular senescence to favor glutamine-dependent survival of esophageal squamous cell carcinoma(ESCC)cells by dictating the activity of LKB1,a critical governor of cancer metabolism.The level of RBM4 was specifically elevated in ESCC compared to normal tissues,and RBM4 overexpression promoted the malignant phenotype.RBM4 contributed to overcome H-RAS-or doxorubicin-induced senescence,while its depletion caused P27-dependent senescence and proliferation arrest by activating LKB1-AMPK-mTOR cascade.Mechanistically,RBM4 competitively bound LKB1 to disrupt the LKB1/STRAD/MO25 heterotrimeric complex,subsequently recruiting the E3 ligase TRIM26 to LKB1,promoting LKB1 ubiquitination and degradation in nucleus.Therefore,such molecular process leads to bypassing senescence and sustaining cell proliferation through the activation of glutamine metabolism.Clinically,the ESCC patients with high RBM4 and low LKB1 have significantly worse overall survival than those with low RBM4 and high LKB1.The RBM4 high/LKB1 low expression confers increased sensitivity of ESCC cells to glutaminase inhibitor CB-839,providing a novel insight into mechanisms underlying the glutamine-dependency to improve the efficacy of glutamine inhibitors in ESCC therapeutics. | Lei Chen Wenjing Zhang Dan Chen Quan Yang Siwen Sun Zhenwei Dai Zhengzheng Li Xuemei Liang Chaoqun Chen Yuexia Jiao Lili Zhi Lianmei Zhao Jinrui Zhang Xuefeng Liu Jinyao Zhao Man Li Yang Wang Yangfan Qi | 2023 | Signal Transduction and Targeted Therapy2023，8，5： | 0 |
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