|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | MEKK1, MKK1/MKK2 and MPK4 function together in a mitogen-activated protein kinase cascade to regulate innate immunity in plants显示文摘激活 Mitogen 的蛋白质 kinase (MAPK ) 串联在调整植物起重要作用天生的有免疫力的回答。在到为有组成的防卫回答的异种的搜索的一幅基因屏幕,我们识别了展出房间死亡和组成的防卫回答的 mpk4 和 mekk1 的多重等位基因。双分子的荧光互补(BiFC ) 分析证明 MPK4 和 MEKK1 与 MKK1 和 MKK2 交往,二密切相关的 MAPK kinases。mkk1 和 mkk2 单身者异种植物没有明显的变异的显型。测试 MKK1 和 MKK2 是否冗余地工作, mkk1 mkk2 两倍异种被产生。mkk1 mkk2 两倍变异的植物在幼苗舞台和幼苗致命性显型死是温度依赖者。类似于 mpk4 和 mekk1 异种,两倍变异的幼苗积累的 mkk1 mkk2 H2O2 高级,显示自发的房间死亡,联系的组成地快速的致病(PR ) 基因和展览病原体抵抗。另外,由 flg22 的 MPK4 的激活在 mkk1 mkk2 被损害两倍异种,在地图 kinase 串联和 MPK4 和 MEKK1 建议那 MKK1 和 MKK2 功能否定地在植物调整天生的有免疫力的回答。 | Minghui Gao Jinman Liu Dongling Bi Zhibin Zhang Fang Cheng2, Sanfeng Chen Yuelin Zhang | 2008 | Cell Research2008，18，12： | 37 |
| 2 | Types,Characteristics and Significances of Migrating Pathways of Gas-bearing Fluids in the Shenhu Area,Northern Continental Slope of the South China Sea显示文摘The first marine gas hydrate expedition in China has been conducted by Guangzhou Marine Geological Survey in the Shenhu Area, northern continental slope of the South China Sea. Previous study has analyzed the P-T conditions, geophysical anomalies and saturation calculations of these gas hydrates, but has not documented in detail the migration of gas-bearing fluids in the study area. Based on the interpretations of 2D/3D seismic data, this work identified two types of migration pathways for gas-bearing fluids in the Shenhu area, i.e., vertical and lateral pathways. The vertical pathways(largescale faults, gas chimneys and mud diapirs) presented as steep seismic reflection anomalies, which could be traced downward to the Eocene source rocks and may penetrate into the Late Miocene strata. The deeper gases/fluids might be allowed migrating into the shallower strata through these vertical conduits. However, the distributions showed distinct differences between these pathways. Large-scale faults developed only in the north and northeast of the Shenhu area, while in the drilling area gas chimneys were the sole vertical migration pathways. Since the Pliocene, normal faults, detachment faults and favorable sediments have constituted the lateral pathways in the Shenhu gas hydrate drilling area. Although these lateral pathways were connected with gas chimneys, they exerted different effects on hydrate formation and accumulation. Gas-bearing fluids migrated upward along gas chimneys might further migrate laterally because of the normal faults, thereby enlarging the range of the chimneys. Linking gas chimneys with the seafloor, the detachment faults might act as conduits for escaping gases/fluids. Re-deposited sediments developed at the early stage of the Quaternary were located within the gas hydrate stability zone, so hydrates would be enriched in these favorable sediments. Compared with the migration pathways(large-scale faults and mud diapirs) in the LW3-1 deep-sea oil/gas field, the migration efficiency of the vertical pathways(composed of gas chimneys) in the gas hydrate drilling area might be relatively low. Description and qualitative discrimination of migration pathways in the Shenhu gas hydrate drilling area are helpful to further understand the relationship between good-quality deep source rocks and shallow, mainly biogenicallyproduced, hydrates. As the main source rocks of the Baiyun sag, lacustrine mudstones in the Wenchang and Enping Formations may provide thermogenic methane. Gas chimneys with relatively low migration efficiency created the vertical pathways. Caused by the Dongsha tectonic movement, the release of overpressured fluids might reduce the vertical migration rates of the thermogenic methane. The thick bathyal/abyssal fine-grained sediments since the Late Miocene provided migration media with low permeability. These preconditions may cause carbon isotopic fractionation ofthermogenic methane during long-distance vertical migrations. Therefore, although geochemical analyses indicate that the methane forming gas hydrate in the Shenhu area was mainly produced biogenically, or was mixed methane primarily of microbial origin, thermogenic methane still contribute significantly. | SU Ming SHA Zhibin ZHANG Cuimei WANG Hongbin WU Nengyou YANG Rui LIANG Jinqiang QIAO Shaohua CONG Xiaorong LIU Jie | 2017 | Acta Geologica Sinica(English Edition)2017，91，1： | 16 |
| 3 | Arabidopsis C3HC4-RING finger E3 ubiquitin ligase At AIRP4 positively regulates stress-responsive abscisic acid signaling显示文摘Degradation of proteins via the ubiquitin system is an important step in many stress signaling pathways in plants.E3 ligases recognize ligand proteins and dictate the high specificity of protein degradation, and thus, play a pivotal role in ubiquitination. Here, we identified a gene, named Arabidopsis thaliana abscisic acid(ABA)-insensitive RING protein 4(At AIRP4), which is induced by ABA and other stress treatments. At AIRP4 encodes a cellular protein with a C3HC4-RING finger domain in its C-terminal side, which has in vitro E3 ligase activity. Loss of At AIRP4 leads to a decrease in sensitivity of root elongation and stomatal closure to ABA, whereas overexpression of this gene in the T-DNA insertion mutant atairp4 effectively recovered the ABA-associated phenotypes. At AIRP4 overexpression plants were hypersensitive to salt and osmotic stresses during seed germination, and showed drought avoidance compared with the wild-type and atairp4 mutant plants. In addition, the expression levels of ABA- and droughtinduced marker genes in At AIRP4 overexpression plants were markedly higher than those in the wild-type and atairp4 mutant plants. Hence, these results indicate that At AIRP4 may act as a positive regulator of ABA-mediated drought avoidance and a negative regulator of salt tolerance in Arabidopsis. | Liang Yang Qiaohong Liu Zhibin Liu Hao Yang Jianmei Wang Xufeng Li Yi Yang | 2016 | Journal of Integrative Plant Biology2016，58，1： | 15 |
| 4 | Risk factors and long-term health consequences of macrosomia:a prospective study in Jiangsu Province,China显示文摘We sought to determine risk factors associated with fetal macrosomia and to explore the long-term consequence of infant macrosomia at the age of 7 years.A prospective population based cohort study was designed to examine the associations between maternal and perinatal characteristics and the risk of macrosomia.A nested case-control study was conducted to explore the long-term health consequence of infant macrosomia.The mean maternal age of the macrosomia group was 24.74±3.32 years,which is slightly older than that in the control group(24.35±3.14 years,P = 0.000).The mean maternal body mass index(BMI) at early pregnancy was 22.75±2.81 kg/m 2,which was also higher than that in the control group(21.76±2.59 kg/m 2,P = 0.000).About 64.6% of macrosomic neonates were males,compared with 51.0% in the control group(P = 0.000).Compared with women with normal weight(BMI:18.5-23.9 kg/m 2),women who were overweight(BMI:24-27.9 kg/m 2) or obese(BMI ≥ 28 kg/m 2),respectively,had a 1.69-fold(P = 0.000) and a 1.49-fold(P = 0.000) increased risks of having a neonate with macrosomia,while light weight(BMI<18.5 kg/m 2) women had an approximately 50% reduction of the risk.Furthermore,macrosomia infant had a 1.52-fold and 1.50-fold risk,respectively,of developing overweight or obesity at the age of 7 years(P = 0.001 and P = 0.000).Older maternal age,higher maternal BMI at early pregnancy and male gender were independent risk factors of macrosomia.Macrosomic infant was associated with an increased predisposition to develop overweight or obesity at the beginning of their childhood. | Shouyong Gu Xiaofei An Liang Fang Xiaomin Zhang Chunyan Zhang Jingling Wang Qilan Liu Yanfang Zhang Yongyue Wei Zhibin Hu Feng Chen Hongbing Shen | 2012 | The Journal of Biomedical Research2012，26，4： | 14 |
| 5 | Factors associated with fatigue in acquired immunodeficiency syndrome patients with antiretroviral drug adverse reactions: a retrospective study显示文摘OBJECTIVE: To retrospectively study the prevalence of fatigue and factors associated with fatigue among acquired immunodeficiency syndrome (AIDS) patients with antiretroviral drug adverse re-ctions. METHODS: Data were collected from case reportforms (CRFs) for a project funded by the 11th National 5-year Special Science and Technology Program on Major Infectious Diseases. Fatigue was defined by patient self-report. The outcomes were the prevalence of fatigue and the potential risk factors of fatigue. Univariate and multivariate logistic regression analyses were conducted to identify the factors associated with fatigue. RESULTS: Among the 228 subjects, the prevalence of fatigue was 86.8%. In univariate analysis, the significant differences in demographic characteristics between patients with and without fatigue were: gender [OR=2.29; 95% CI (1.05-4.98)], education level [OR=0.40; 95% CI (0.18-0.85)], anemia [OR=3.80; 95% CI (1.27-11.31)], time of HIV diagnosis [OR= 0.29; 95% CI (0.13-0.65)], and route of infection [OR= 0.14; 95% CI (0.06-0.32)]. Abnormal taste and rapid pulse were more commonly seen in patients with fatigue (P<0.05), while abdominal distension and lumbar soreness were encountered less often in patients with fatigue (P<0.05). Multivariate analysis showed that the four main factors associated with fatigue were anemia [OR=3.50; 95% CI (1.01-12.15)], route of infection [OR=3.40; 95% CI (1.21-9.58); P= 0.02<0.05], lumbar soreness [OR=0.06; 95% CI (0.02-0.18); P=0.000<0.05], and rapid pulse [OR= 10.58; 95% CI (2.16-51.75); P=0.004<0.05]. CONCLUSION: This study demonstrated that fa- tigue is common (86.8% prevalence) in AIDS patients with antiretroviral drug adverse reactions, and that anemia, route of infection (i.e., non-commercial blood donation) and rapid pulse were risk factors, while lumbar soreness was a protective factor related to fatigue. More attention should bepaid to fatigue and more efforts should be made to find ways to prevent, control and eliminate this symptom in AIDS patients with antiretroviral drug adverse reactions. | Zhibin Liu Jiping Yang Huijuan Liu Yantao Jin | 2013 | Journal of Traditional Chinese Medicine2013，33，3： | 12 |
| 6 | The effect of dissolved oxygen concentration on long-term stability of partial nitrification process显示文摘Dissolved oxygen(DO)concentration is regarded as one of the crucial factors to influence partial nitrification process.However,achieving and keeping stable partial nitrification under different DO concentrations were widely reported.The mechanism of DO concentration influencing partial nitrification is still unclear.Therefore,in this study two same sequencing batch reactors(SBRs)cultivated same seeding sludge were built up with realtime control strategy.Different DO concentrations were controlled in SBRs to explore the effect of DO concentration on the long-term stability of partial nitrification process at room temperature.It was discovered that ammonium oxidation rate(AOR)was inhibited when DO concentration decreased from 2.5 to 0.5 mg/L.The abundance of Nitrospira increased from 1011.5 to 1013.7 copies/g DNA,and its relative percentage increased from 0.056%to 3.2%during 190 operational cycles,causing partial nitrification gradually turning into complete nitrification process.However,when DO was 2.5 mg/L the abundance of Nitrospira was stable and AOB was always kept at 1010.7 copies/g DNA.High AOR was maintained,and stable partial nitrification process was kept.Ammonia oxidizing bacteria(AOB)activity was significantly higher than nitrite oxidizing bacteria(NOB)activity at DO of 2.5 mg/L,which was crucial to maintain excellent nitrite accumulation performance. | Bin Cui Qing Yang Xiuhong Liu Siting Huang Yubing Yang Zhibin Liu | 2020 | Journal of Environmental Sciences2020，32，4： | 12 |
| 7 | Using a support vector machine method to predict the development indices of very high water cut oilfields显示文摘Because the oilfields in eastern China are in the very high water cut development stage, accurate forecast of oilfield development indices is important for exploiting the oilfields efficiently. Regarding the problems of the small number of samples collected for oilfield development indices, a new support vector regression prediction method for development indices is proposed in this paper. This method uses the principle of functional simulation to determine the input-output of a support vector machine prediction system based on historical oilfield development data. It chooses the kernel function of the support vector machine by analyzing time series characteristics of the development index; trains and tests the support vector machine network with historical data to construct the support vector regression prediction model of oilfield development indices; and predicts the development index. The case study shows that the proposed method is feasible, and predicted development indices agree well with the development performance of very high water cut oilfields. | Zhong Yihua Zhao Lei Liu Zhibin Xu Yao Li Rong | 2010 | Petroleum Science2010，7，3： | 11 |
| 8 | Effects of combined acupuncture and eugenol on learning-memory ability and antioxidation system of hippocampus in Alzheimer disease rats via olfactory system stimulation显示文摘OBJECTIVE: To investigate the effects of combined acupuncture and eugenol on learning-memory ability and the antioxidation system of the hippocampus in Alzheimer disease (AD) rats. METHODS: Sixty Sprague Dawley rats, weighing (300±10) g, were randomly divided with 10 rats per group into a normal control group, AD model group, AD with cut olfactory nerve group, Xiu three-needle group, eugenol group, and combined acupuncture and eugenol group. The AD model was established by injection of amyloid β1-40 (Aβ 1-40). Morris maze tests were conducted for evaluating the learning-memory ability. Content of malo- ndialdehyde (MDA) and activities of superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) in the hippocampus were detected. RESULTS: The average escape latency and the mean swimming distance in the normal control group, the Xiu three-needle group, the eugenol group, and the combined acupuncture and euge-nol group were significantly shorter than those in the AD model group (all P<0.01). The combined acupuncture and eugenol group had shorter escape latency and mean swimming distance than those in the Xiu three-needle group and the eugenol group. There were no significant differences between the Xiu three-needle group and the eugenol group and between the AD group and the AD with cut olfactory nerve group (P>0.05). Compared with the normal control group, the MDA content in the hippocampus significantly increased (P<0.05) and GSH-Px and SOD activities significantly decreased in the AD model group (P<0.01). Compared with the AD model group, significantly decreased (P< 0.01) and SOD and GSH-Px activities significantly increased in the Xiu three-needle group, eugenol group, and combined acupuncture and eugenol group (P<0.05). Compared with the Xiu three-needle group and eugenol group, the MDA content significantly decreased (P<0.05) and SOD and GSH-Px activities increased (P<0.05) in the combined acupuncture and eugenol group. There were no significant differences among the three indices between the Xiu three-needle group and the eugenol group and between the AD model group and the AD with cut olfactory nerve group (P>0.05). CONCLUSION: Both Xiu three-needle and eugenol can increase learning-memory ability, decrease MDA content, and increase SOD and GSH-Px activities in the hippocampus in AD rats. The combination of acupuncture with eugenol has stronger effects, and the effects depend on the olfactory pathway. | Zhibin Liu Wenmin Niu Xiaohang Yang Yuan Wang | 2013 | Journal of Traditional Chinese Medicine2013，33，3： | 10 |
| 9 | Survival of people living with HIV after treatment with Traditional Chinese Medicine in Henan province of China: a retrospective cohortstudy显示文摘OBJECTIVE: To provide survival estimates of people living with human immunodeficiency virus(PLHIV) after treatment with Traditional Chinese Medicine(TCM) in rural China, to identify the prognostic factors at enrollment, and to explore the effectiveness of TCM intreating PLHIV.METHODS: PLHIV who enrolled in national TCM HIV treatment trial program in October 2004 were analyzed in this study and followed up to October 2010. Survival time was estimated by the Kaplan-Meier curve and hazard ratios, and identifying prognostic factors were computed through Cox proportional hazard models.RESULTS:A total of 1666 PLHIV were included with 102 591 person-months of follow-up. Overall, 312(18.7%) patients died. The total mortality rate over the study period was 3.6 per 100 person-years,which was lower than the worldwide rate. The cumulative survival rate was 95.9% at 1 year[95% confidence interval(CI)(94.8-96.8)] and 80.4% at 6years [95% CI(78.4-82.3)]. Elevated death risks emerged among males, older individuals, and thosewithlowerCD4+T-cellcounts.CONCLUSION: TCM could increase survival and lengthen the life span of PLHIV in Henan province of China, as shown by our retrospective cohort study. Factors such as sex, age, education, and CD4+ T-cell counts correlated to survival. However,retrospective cohorts bias the data, so more prospective studies should be performed to confirm our primary results. | Yantao Jin Zhibin Liu Xiumin Chen Xin Wang Dan Wang Ziqiang Jiang Ying Liu Jian Wang Wen Zou Huijun Guo Liran Xu | 2014 | Journal of Traditional Chinese Medicine2014，34，4： | 8 |
| 10 | Differences in acquired immune deficiency syndrome treatment and evaluation strategies between Chinese and Western Medicine显示文摘Complementary and alternative medicine, including Chinese medicine(CM), has been used to treat acquired immune deficiency syndrome(AIDS) for almost 30 years. We aimed to compare the main differences between AIDS treatment and evaluation strategies between CM and Western Medicine(WM), and analyze advantages and disadvantages.The characteristics of integrative medicine(IM),based on CM and WM, include a patient-centered mode of medicine based on evidence. IM focuses on complex intervention and management with systemic and individual treatment. The evaluation indexes of IM might consist of objective indicators and subjective indexes. IM might be a more valuable method for treating AIDS in the future instead of WM or CM alone. | Liu Zhibin Li Xia Yang Jiping Xu Liran Guo Huijun | 2015 | Journal of Traditional Chinese Medicine2015，35，6： | 8 |
| 11 | Development and path planning of a novel unmanned surface vehicle system and its application to exploitation of Qarhan Salt Lake显示文摘Qarhan Salt Lake is rich in mineral resources, such as sodium chloride, potassium, and magnesium [1]. At present, liquid mine exploiting is the main exploitation form for the Qarhan Salt Lake. Salt mining ships with mining equipments are widely used to exploit carnallite which is located at the bottom of pools. Conventionally, workmen utilize rude ferric sampler to collect carnallite samples and estimate their thickness, providing guidance to the salt mining ship [2]. However, the turbid brine and uneven carnallite reduce the efficiency of exploitation, which could no longer meet the rapid mining requirements. | Zhibin XUE Jincun LIU Zhengxing WU Sheng DU Shihan KONG Junzhi YU | 2019 | Science China(Information Sciences)2019，62，8： | 8 |
| 12 | Genetic Polymorphisms in the Precursor MicroRNA Flanking Region and Non-Small Cell Lung Cancer Survival显示文摘 | Hu, Zhibin Shu, Yongqian Chen, Yijiang Chen, Jiaping Dong, Jing Liu, Yao Pan, Shiyang Xu, Lin Xu, Jing Wang, Yi Dai , Juncheng Ma, Hongxia Jin, Guangfu Shen,Hongbing | 2011 | 南京医科大学学报(自然科学版)2011，31，6： | 8 |
| 13 | Genetic variants in RAN, DICER and HIWI of microRNA biogenesis genes and risk of cervical carcinoma in a Chinese population显示文摘Objective:Recent evidence indicates that dysregulation of microRNA(miRNA)biogenesis is implicated in cancer development and progression.Based on the important role of miRNA biogenesis genes in carcinogenesis,we hypothesized that genetic variations of the miRNA biogenesis genes may modulate susceptibility to cervical cancer.Methods:We identified three single nucleotide polymorphisms(SNPs)located in the 3'-untranslated regions(3'-UTR)of of miRNA biogenesis key genes(rs1057035 in DICER,rs3803012 in RAN and rs10773771 in HIWI)and genotyped these SNPs in a case-control study of 1,486 cervical cancer cases and1,549 cancer-free controls in Chinese women.Results:Logistic regression analyses showed that no significant associations were observed between the three SNPs and cervical cancer risk[rs3803012 in RAN AG/GG vs.AA adjusted OR=1.104,95%confidence interval(CI):0.859-1.419;rs1057035 in DICER CT/CC vs.TT adjusted OR=0.962,95%CI:0.805-1.149;rs10773771 in HIWI CT/CC vs.TT adjusted OR=0.963,95%CI:0.826-1.122].Conclusions:The findings did not suggest that genetic variants in the 3'-UTR of RAN,DICER and HIWI of miRNA biogenesis genes were associated with the risk of cervical cancer in this Chinese population. | Jiaping Chen Zhenzhen Qin Shandong Pan Jie Jiang Li Liu Jibin Liu Xiaojun Chen Zhibin Hu Hongbing Shen | 2013 | Chinese Journal of Cancer Research2013，25，5： | 8 |
| 14 | Detection of serum IgM and IgG for COVID-19 diagnosis显示文摘Dear Editor,Infection with the novel coronavirus(SARS-CoV-2,which is the virus responsible for the coronavirus disease 2019(COVID-19))was first reported in Wuhan,China on December 31,2019.The outbreak of COVID-19 remains ongoing and was linked to more than 80,000 infected patients and more than 3,000 deaths in China as of March 7,2020(Holshue et al.,2020). | Ling Zhong Junlan Chuan Bo Gong Ping Shuai Yu Zhou Yi Zhang Zhilin Jiang Dingding Zhang Xiaoqi Liu Shi Ma Yi Huang He Lin Qingwei Wang Lulin Huang Dan Jiang Fang Hao Juan Tang Chunqi Zheng Hua Yu Zhibin Wang Qi Jiang Tao Zeng Mei Luo Fanwei Zeng Fanxin Zeng Jianghai Liu Junxi Tian Yu Xu Tengxiang Long Kaiju Xu Xingxiang Yang Yuping Liu Yi Shi Li Jiang Zhenglin Yang | 2020 | Science China(Life Sciences)2020，63，5： | 8 |
| 15 | Curative effect of scraping therapies on lumbar muscle strain显示文摘OBJECTIVE:To explore factors influencing the curative effect of scraping therapies (at acupoints or along channels) and to determine the relationship of scraping site and strength to curative effect. METHODS: Two hundred and ten patients with lumbar muscle strain were divided into five groups with 42 patients each.The 'scraping therapy at acupoint until appearance of skin eruptions' and 'scraping therapy along channel until appearance of skin eruptions' groups were treated with a 4-daycourse. The 'scraping therapy at acupoint without appearance of skin eruptions', 'scraping therapy along channel without appearance of skin eruptions', and acupuncture groups were treated with a 2-day course.The five groups were treated with seven courses. The visual analog scale (VAS), oswestry disability index (ODI), and lumbago scores were recorded in the five groups before treatment, after each treatment, and in follow-up visits one month and three months after treatment. RESULTS: VAS, ODI, and lumbago scores after treatment improved in the five groups (P<0.01). There was a statistical difference (P<0.01) in the change of VAS scores by appearance of skin eruptions and scraping site. CONCLUSION: Scraping therapy can effectively alleviate lumbago symptoms. The appearance of skin eruptions and scraping therapy along channels can enhance the curative effect of scraping therapy. | Yingying Wang Li Yang Jinsheng Yang Jinhong Yang Zhibin Liu Feng Chen Dongxia Liu Haiguang Yuan Liang Wang | 2013 | Journal of Traditional Chinese Medicine2013，33，4： | 7 |
| 16 | Pressure Regulation for Earth Pressure Balance Control on Shield Tunneling Machine by Using Adaptive Robust Control显示文摘Most current studies about shield tunneling machine focus on the construction safety and tunnel structure stability during the excavation. Behaviors of the machine itself are also studied, like some tracking control of the machine. Yet, few works concern about the hydraulic components, especially the pressure and flow rate regulation components. This research focuses on pressure control strategies by using proportional pressure relief valve, which is widely applied on typical shield tunneling machines. Modeling of a commercial pressure relief valve is done. The modeling centers on the main valve, because the dynamic performance is determined by the main valve. To validate such modeling, a frequency-experiment result of the pressure relief valve, whose bandwidth is about 3 Hz, is presented as comparison. The modeling and the frequency experimental result show that it is reasonable to regard the pressure relief valve as a second-order system with two low corner frequencies. PID control, dead band compensation control and adaptive robust control(ARC) are proposed and simulation results are presented. For the ARC, implements by using first order approximation and second order approximation are presented. The simulation results show that the second order approximation implement with ARC can track 4 Hz sine signal very well, and the two ARC simulation errors are within 0.2 MPa. Finally, experiment results of dead band compensation control and adaptive robust control are given. The results show that dead band compensation had about 30° phase lag and about 20% off of the amplitude attenuation. ARC is tracking with little phase lag and almost no amplitude attenuation. In this research, ARC has been tested on a pressure relief valve. It is able to improve the valve's dynamic performances greatly, and it is capable of the pressure control of shield machine excavation. | XIE Haibo LIU Zhibin YANG Huayong | 2016 | Chinese Journal of Mechanical Engineering2016，29，3： | 7 |
| 17 | Survival rate:an indicator of the management of acquired immune deficiency syndrome using Traditional Chinese Medicine显示文摘Complementary and alternative medicine,including Traditional Chinese Medicine(TCM),has been used as therapy against acquired immune deficiency syndrome(AIDS) for almost 30 years. Based on evaluation indicators for AIDS treatment using TCM,we discuss why the survival rate(which has been used widely in Western Medicine) should be adopted as a new important indicator of TCM treatment for AIDS. We advise that further prospective or retrospective cohort studies should be carried out to confirm this hypothesis. | Liu Zhibin Meng Changhai Yang Jiping Chen Xiumin Jin Yantao | 2015 | Journal of Traditional Chinese Medicine2015，35，4： | 7 |
| 18 | Stochastic modelling of soil moisture dynamics in a grassland of Qilian Mountain at point scale显示文摘Stochastic modeling of soil moisture dynamics is crucial to the quantitative understanding of plant responses to water stresses,hydrological control of nutrient cycling processes,water competition among plants,and some other ecological dynamics,and thus has become a hotspot in ecohydrology at present.In this paper,we based on the continuously monitored data of soil moisture during 2002―2005 and daily precipitation date of 1992―2006,and tried to make a probabilistic analysis of soil moisture dynamics at point scale in a grassland of Qilian Mountain by integrating the stochastic model improved by Laio and the Monte Carlo method.The results show that the inter-annual variations for the soil moisture patterns at different depths are very significant,and that the coefficient of variance(CV) of surface soil moisture(20 cm) is almost continually kept at about 0.23 whether in the rich or poor rainy years.Interestingly,it has been found that the maximal CV of soil moisture has not always appeared at the surface layer.Comparison of the analytically derived soil moisture probability density function(PDF) with the statistical distribution of the observed soil moisture data suggests that the stochastic model can reasonably describe and predict the soil moisture dynamics of the grassland in Qilian Mountain at point scale.By extracting the statistical information of the historical precipitation data in 1994―2006,and inputting them into the stochastic model,we analytically derived the long-term soil moisture PDF without considering the inter-annual climate fluctuations,and then numerically derived the one when considering the inter-annual fluctuation effects in combination with a Monte-Carlo procedure.It was found that,though the peak position of the probability density distribution significantly moved towards drought when considering the disturbance forces,and its width was narrowed,accordingly its peak value was increased,no significant bimodality was observed in the soil moisture dynamics under the given intensity of random fluctuation disturbance. | LIU Hu,ZHAO WenZhi HE ZhiBin & ZHANG LiJie Linze Inland River Basin Research Station,Chinese Ecosystem Research Network Laboratory of Watershed Hydrology and Ecol-ogy,Cold and Arid Regions Environmental and Engineering Research Institute,Chinese Academy of Sciences,Lanzhou 730000,China | 2007 | Science China Earth Sciences2007，50，12： | 7 |
| 19 | Prognostic assessment of apoptotic gene polymorphisms in non-small cell lung cancer in Chinese显示文摘Apoptosis plays a key role in inhibiting tumor growth, progression and resistance to anti-tumor therapy. We hypothesized that genetic variants in apoptotic genes may affect the prognosis of lung cancer. To test this hypothesis, we selected 38 potentially functional single nucleotide polymorphisms (SNPs) from 12 genes (BAX, BCL2, BID, CASP3, CASP6, CASP7, CASP8, CASP9, CASP10, FAS, FASLG and MCL1) involved in apoptosis to assess their prognostic significance in lung cancer in a Chinese case cohort with 568 non-small cell lung cancer (NSCLC) patients. Thirty-five SNPs passing quality control underwent association analyses, 11 of which were shown to be significantly associated with NSCLC survival (P<0.05). After Cox stepwise regression analyses, 3 SNPs were independently associated with the outcome of NSCLC (BID rs8190315: P=0.003; CASP9 rs4645981: P=0.007 and FAS rs1800682: P=0.016). A favorable survival of NSCLC was significantly associated with the genotypes of BID rs8190315 AG/GG (adjusted HR=0.65, 95% CI: 0.49-0.88), CASP9 rs4645981 AA (HR=0.22, 95% CI: 0.07-0.69) and FAS rs1800682 GG (adjusted HR=0.67, 95% CI: 0.46-0.97). Time-dependent receptor operation curve (ROC) analysis revealed that the area under curve (AUC) at year 5 was significantly increased from 0.762 to 0.819 after adding the risk score of these 3 SNPs to the clinical risk score. The remaining 32 SNPs were not significantly associated with NSCLC prognosis after adjustment for these 3 SNPs. These findings indicate that BID rs8190315, CASP9 rs4645981 and FAS rs1800682 polymorphisms in the apoptotic pathway may be involved in the prognosis of NSCLC in the Chinese population. | Songyu Cao Cheng Wang Xinen Huang Juncheng Dai Lingmin Hu Yao Liu Jiaping Chen Hongxia Ma Guangfu Jin Zhibin Hu Lin Xu Hongbing Shen | 2013 | The Journal of Biomedical Research2013，27，3： | 6 |
| 20 | Effects of Different Biochars on Pinus elliottii Growth,N Use Efficiency,Soil N_2O and CH_4 Emissions and C Storage in a Subtropical Area of China显示文摘Intensive management of planted forests may result in soil degradation and decline in timber yield with successive rotations.Biochars may be beneficial for plant production, nutrient uptake and greenhouse gas mitigation. Biochar properties vary widely and are known to be highly dependent on feedstocks, but their effects on planted forest ecosystem are elusive. This study investigated the effects of chicken manure biochar, sawdust biochar and their feedstocks on 2-year-old Pinus elliottii growth, fertilizer N use efficiency(NUE), soil N_2O and CH_4 emissions, and C storage in an acidic forest soil in a subtropical area of China for one year. The soil was mixed with materials in a total of 8 treatments: non-amended control(CK); sawdust at 2.16 kg m-^(2)(SD); chicken manure at 1.26 kg m-^(2)(CM); sawdust biochar at 2.4 kg m-^(2)(SDB); chicken manure biochar at 2.4 kg m-^(2)(CMB);^(15)N-fertilizer alone(10.23 atom%^(15)N)(NF); sawdust biochar at 2.4 kg m-^(2)plus15N-fertilizer(SDBN) and chicken manure biochar at 2.4 kg m-^(2)plus15N-fertilizer(CMBN). Results showed that the CMB treatment increased P. elliottii net primary production(aboveground biomass plus litterfall)and annual net C fixation(ANCF) by about 180% and 157%, respectively, while the the SDB treatment had little effect on P. elliottii growth. The15 N stable isotope labelling technique revealed that fertilizer NUE was 22.7% in CK, 25.5% in the NF treatment, and37.0% in the CMB treatment. Chicken manure biochar significantly increased soil p H, total N, total P, total K, available P and available K. Only 2% of the N in chicken manure biochar was available to the tree. The soil N_2O emission and CH_4 uptake showed no significant differences among the treatments. The apparent C losses from the SD and CM treatments were 35% and 61%, respectively;while those from the CMB and SDB treatments were negligible. These demonstrated that it is crucial to consider biochar properties while evaluating their effects on plant growth and C sequestration. | LIN Zhibin LIU Qi LIU Gang Annette L.COWIE BEI Qicheng LIU Benjuan WANG Xiaojie MA Jing ZHU Jianguo XIE Zubin | 2017 | Pedosphere2017，27，2： | 6 |
您所在的机构暂未开通此部分的功能，请联系管理员