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| 1 | Application of next-generation sequencing technology to precision medicine in cancer: joint consensus of the Tumor Biomarker Committee of the Chinese Society of Clinical Oncology显示文摘Next-generation sequencing(NGS) technology is capable of sequencing millions or billions of DNA molecules simultaneously.Therefore, it represents a promising tool for the analysis of molecular targets for the initial diagnosis of disease, monitoring of disease progression, and identifying the mechanism of drug resistance. On behalf of the Tumor Biomarker Committee of the Chinese Society of Clinical Oncology(CSCO) and the China Actionable Genome Consortium(CAGC), the present expert group hereby proposes advisory guidelines on clinical applications of NGS technology for the analysis of cancer driver genes for precision cancer therapy. This group comprises an assembly of laboratory cancer geneticists, clinical oncologists, bioinformaticians,pathologists, and other professionals. After multiple rounds of discussions and revisions, the expert group has reached a preliminary consensus on the need of NGS in clinical diagnosis, its regulation, and compliance standards in clinical sample collection. Moreover, it has prepared NGS criteria, the sequencing standard operation procedure(SOP), data analysis, report, and NGS platform certification and validation. | Xuchao Zhang Zhiyong Liang Shengyue Wang Shun Lu Yong Song Ying Cheng Jianming Ying Weiping Liu Yingyong Hou Yangqiu Li Yi Liu Jun Hou Xiufeng Liu Jianyong Shao Yanhong Tai Zheng Wang Li Fu Hui Li Xiaojun Zhou Hua Bai Mengzhao Wang You Lu Jinji Yang Wenzhao Zhong Qing Zhou Xuening Yang Jie Wang Cheng Huang Xiaoqing Liu Xiaoyan Zhou Shirong Zhang Hongxia Tian Yu Chen Ruibao Ren Ning Liao Chunyan Wu Zhongzheng Zhu Hongming Pan Yanhong Gu Liwei Wang Yunpeng Liu Suzhan Zhang Tianshu Liu Gong Chen Zhimin Shao Binghe Xu Qingyuan Zhang Ruihua Xu Lin Shen Yilong Wu | 2019 | Cancer Biology & Medicine2019,16,1: | 14 |
| 2 | Standardized Operational Protocol for Human Brain Banking in China显示文摘With the progress of society, there is an increasing need to tackle disorders of the central nervous system. Human brain tissue, unlike animal tissues, is an irreplaceable resource for the study of neurological diseases (1)Aimed at scientific research and education, the roles of human brain tissue repositories are to acquire brain tissue from donors, prepare, process, and preserve collected samples,provide tissue to specific eligible facilities, and determine the characteristics of each tissue sample. | Wenying Qiu Hanlin Zhang Aimin Bao Keqing Zhu Yue Huang Xiaoxin Yan Jing Zhang Chunjiu Zhong Yong Shen Jiangning Zhou Xiaoying Zheng Liwei Zhang Yousheng Shu Beisha Tang Zhenxin Zhang Gang Wang Ren Zhou Bing Sun Changlin Gong Shumin Duan Chao Ma | 2019 | Neuroscience Bulletin2019,35,2: | 6 |
| 3 | An Expedient Method for Regioselective Methylation of Catechol Coumarins显示文摘 | LU Junxia WANG Ping HOU Jie ZOU Liwei CUI Pan YANG Ling GE Guangbo GONG Xiaojie | 2016 | Chemical Research in Chinese Universities2016,32,5: | 1 |
| 4 | A high expression level of insulin-like growth factor I receptor is associated with increased expression of transcription factor Sp1 and regional lymph node metastasis of human gastric cancer显示文摘 | Yixing Jiang Liwei Wang Weida Gong Daoyan Wei Xiangdong Le James Yao Jaffer Ajani James L. Abbruzzese Suyun Huang Keping Xie | 2005 | Clinical & Experimental Metastasis2005,,8: | 1 |
| 5 | Association of elevated GRP78 expression with increased lymph node metastasis and poor prognosis in patients with gastric cancer显示文摘 | Jun Zhang Yixing Jiang Zhiliang Jia Qiang Li Weida Gong Liwei Wang Daoyan Wei James Yao Shengyun Fang Keping Xie | 2006 | 2006 (7-8)2006,,7: | 1 |
| 6 | High-speed Simultaneous Image Distortion Correction Transfor- mations for a Multicamera Cylindrical Panorama Real- time Video System Using FPGA 显示文摘 | Xu Yuan Zhou Qinghai Gong Liwei | 2014 | IEEE Transactions on Circuits and Systems for Video Technology2014,24,6: | 1 |
| 7 | Stacking monolayers at will:A scalable device optimization strategy for two-dimensional semiconductors显示文摘In comparison to monolayer(1L),multilayer(ML)two-dimensional(2D)semiconducting transition metal dichalcogenides(TMDs)exhibit more application potential for electronic and optoelectronic devices due to their improved current carrying capability,higher mobility,and broader spectral response.However,the investigation of devices based on wafer-scale ML-TMDs is still restricted by the synthesis of uniform and high-quality ML films.In this work,we propose a strategy of stacking MoS_(2) monolayers via a vacuum transfer method,by which one could obtain wafer-scale high-quality MoS_(2) films with the desired number of layers at will.The optical characteristics of these stacked ML-MoS_(2) films(>2L)indicate a weak interlayer coupling.The stacked MLMoS_(2) phototransistors show improved optoelectrical performances and a broader spectral response(approximately 300-1,000 nm)than that of 1L-MoS_(2).Additionally,the dual-gate ML-MoS_(2) transistors enable enhanced electrostatic control over the stacked ML-MoS_(2) channel,and the 3L and 4L thicknesses exhibit the optimal device performances according to the turning point of the current on/off ratio and the subthreshold swing. | Xiaojiao Guo Honglei Chen Jihong Bian Fuyou Liao Jingyi Ma Simeng Zhang Xinzhi Zhang Junqiang Zhu Chen Luo Zijian Zhang Lingyi Zong Yin Xia Chuming Sheng Zihan Xu Saifei Gou Xinyu Wang Peng Gong Liwei Liu Xixi Jiang Zhenghua An Chunxiao Cong Zhijun Qiu Xing Wu Peng Zhou Xinyu Chen Ling Tong Wenzhong Bao | 2022 | Nano Research2022,15,7: | 0 |
| 8 | Hyperspectral and multispectral remote sensing image fusion using SwinGAN with joint adaptive spatial-spectral gradient loss function显示文摘Hyperspectral remote sensing image(HSI)fusion with multispectral remote sensing images(MSI)improves data resolution.However,current fusion algorithms focus on local information and overlook long-range dependencies.The parameter of network tuning prioritizes global optimization,neglecting spatial and spectral constraints,and limiting spatial and spectral reconstruction capabilities.This study introduces SwinGAN,a fusion network combining Swin Transformer,CNN,and GAN architectures.SwinGAN’s generator employs a detail injection framework to separately extract HSI and MSI features,fusing them to generate spatial residuals.These residuals are injected into the supersampled HSI to produce thefinal image,while a pure CNN architecture acts as the discriminator,enhancing the fusion quality.Additionally,we introduce a new adaptive loss function that improves image fusion accuracy.The loss function uses L1 loss as the content loss,and spatial and spectral gradient loss functions are introduced to improve the spatial representation and spectralfidelity of the fused images.Our experimental results on several datasets demonstrate that SwinGAN outperforms current popular algorithms in both spatial and spectral reconstruction capabilities.The ablation experiments also demonstrate the rationality of the various components of the proposed loss function. | Chunyu Zhu Shangqi Deng Jiaxin Li Ying Zhang Liwei Gong Liangbo Gao Na Ta Shengbo Chen Qiong Wu | 2023 | International Journal of Digital Earth2023,16,1: | 0 |
| 9 | Synthesis of Bi_(6)O_(6)(OH)_(3)(NO_(3))_(3)·1.5H_(2)O/ZnO composite material with excellent photocatalytic hydrogen production performance显示文摘The heterojunction effect can effectively improve the separation efficiency of the photocatalyst’s photo-generated electron and hole pairs,thereby greatly improving the photocatalytic hydrogen production performance of the photocatalyst.In this paper,Bi_(6)O_(6)(OH)_(3)(NO_(3))_(3)·1.5H_(2)O(BBN)and ZnO are used to construct and synthesize Bi_(6)O_(6)(OH)_(3)(NO_(3))_(3)·1.5H_(2)O/ZnO(BBN/ZnO)heterojunction photocatalyst.Under UV-vis light irradiation,the BBN/ZnO composite could generate H_(2)with a rate of 28.66μmol·g^(−1)·h^(−1),which is higher than pure BBN(0.92μmol·g^(−1)·h^(−1))and ZnO(6.54μmol·h^(−1)·g^(−1))at around 31.1 and 4.4 times,respectively.Moreover,the experimental results found that the composite still exhibits excellent photocatalytic activity and maintains a high and stable activity in the 12-hour experiment with 3 cycles.The possible mechanism to enhance the photocatalytic behavior is attributed to the expanded light absorption range,reduced surface migration resistance,and inhibited recombination of photo-generated electron and hole pairs. | Lingyi Wang Shichang Sun Ziqing Zhong Qingguang Gong Xingpeng Jiang Weiming Zhou Liwei Wang Ming Lin Zhanhui Yuan | 2021 | International Journal of Smart and Nano Materials2021,12,2: | 0 |