|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Marine Yeasts and Their Applications in Mariculture显示文摘The terrestrial yeasts have been receiving great attention in science and industry for over one hundred years because they can produce many kinds of bioactive substances. However, little is known about the bioactive substances of marine yeasts. In recent years, it has been found that marine yeasts have wide applications in mariculture and other fields. Therefore,marine yeasts, the bioactive substances from them and the applications of marine yeasts themselves and the bioactive substances they produced are reviewed in this paper. | CHI Zhenming LIU Zhiqiang GAO Lingmei GONG Fang MA Chunling WANG Xianghong LI Haifeng | 2006 | Journal of Ocean University of China2006，5，3： | 12 |
| 2 | Comparative Immunization in BALB/c Mice with Recombinant Replication-Defective Adenovirus Vector and DNA Plasmid Expressing a SARS-CoV Nucleocapsid Protein Gene显示文摘In order to investigate immunogenicity in the induction of humoral and cellular immune responses, severe acute respiratory syndrome associated coronavirus (SARS-CoV)-N gene recombinant replication-defective adenoviral vector, rAd-N, was generated and immunized BALB/c mice in a pcDNA3.1-N prime-rAd-N boost regimen. After humoral and cellular immune response detection, different levels of SARS-CoV N protein specific antibodies and interferon-γ (IFN-γ) secretion are shown compared to controls. The humoral immune response was induced more effectively by the DNA priming and recombinant adenovirus boosting regimen. There is a significant difference between heterogeneous and homologous vaccinations. The heterogeneous combinations were all higher than those of the homologous combinations in the induction of anti-N antibody response. Among the three heterogeneous combinations, pcDNA3.1-N/pcDNA3.1-N/pcDNA3.1-N/rAd-N induced the strongest antibody response. In the induction of IFN-γ production, the homologous combination of rAd-N/rAd-N/rAd-N/rAd-N was significantly stronger than that of pcDNA3.1-N/pcDNA3.1-N/pcDNA3.1-N/pcDNA3.1-N, but was relatively weaker than the heterogeneous combination of pcDAN3.1-N/pcDAN3.1-N/pcDAN3.1-N/rAd-N. This combination was a most efficient immunization regimen in induction of SARS-CoV-N-specific (IFN-γ) secretion just as the antibody response. These results suggest that DNA immunization followed by recombinant adenovirus boosting could be used as a potential SARS-CoV vaccine. | Chunling Ma Kun Yao Feng Zhou Minsheng Zhu | 2006 | Cellular & Molecular Immunology2006，3，6： | 10 |
| 3 | Origin and accumulation of high-maturity oil and gas in deep parts of the Baxian Depression, Bohai Bay Basin, China显示文摘Great quantities of light oil and gas are produced from deep buried hill reservoirs at depths of 5,641 m to 6,027 m and 190 °C to 201 °C in the Niudong-1 Well, representing the deepest and hottest commercial hydrocarbons discovered in the Bohai Bay Basin in eastern China. This discovery suggests favorable exploration prospects for the deep parts of the basin. However, the discovery raises questions regarding the genesis and accumulation of hydrocarbons in deep reservoirs. Based on the geochemical features of the hydrocarbons and characteristics of the source rocks as well as thermal simulation experiments of hydrocarbon generation, we conclude that the oil and gas were generated from the highly mature Sha-4 Member (Es4 ) source rocks instead of thermal cracking of crude oils in earlier accumulations. The source kitchen with abnormal pressures and karsted carbonate reservoirs control the formation of high-maturity hydrocarbon accumulations in the buried hills (i.e., Niudong-1) in conjunction with several structural-lithologic traps in the Es4 reservoirs since the deposition of the upper Minghuazhen Formation. This means the oil and gas exploration potential in the deep parts of the Baxian Depression is probably high. | Zhao Xianzheng Jin Qiang Jin Fengming Ma Peng Wang Quan Wang Jing Ren Chunling Xi Qiuling | 2013 | Petroleum Science2013，10，3： | 10 |
| 4 | Olmutinib(HM61713) reversed multidrug resistance by inhibiting the activity of ATPbinding cassette subfamily G member 2 in vitro and in vivo显示文摘Overexpressing of ATP-binding cassette(ABC) transporters is the essential cause of multidrug resistance(MDR), which is a significant hurdle to the success of chemotherapy in many cancers.Therefore, inhibiting the activity of ABC transporters may be a logical approach to circumvent MDR.Olmutinib is an epidermal growth factor receptor(EGFR) tyrosine kinase inhibitor(TKI), which has been approved in South Korea for advanced EGFR T790 M-positive non-small cell lung cancer(NSCLC). Here,we found that olmutinib significantly increased the sensitivity of chemotherapy drug in ABCG2-overexpressing cells. Furthermore, olmutinib could also increase the retention of doxorubicin(DOX) and rhodamine 123(Rho 123) in ABC transporter subfamily G member 2(ABCG2)-overexpressing cells. In addition, olmutinib was found to stimulate ATPase activity and inhibit photolabeling of ABCG2 with [^(125) I]-iodoarylazidoprazosin(IAAP). However, olmutinib neither altered ABCG2 expression at protein and m RNA levels nor blocked EGFR, Her-2 downstream signaling of AKT and ERK. Importantly,olmutinib enhanced the efficacy of topotecan on the inhibition of S1-MI-80 cell xenograft growth. All the results suggest that olmutinib reverses ABCG2-mediated MDR by binding to ATP bind site of ABCG2 and increasing intracellular chemotherapeutic drug accumulation. Our findings encouraged to further clinical investigation on combination therapy of olmutinib with conventional chemotherapeutic drugs in ABCG2-overexpressing cancer patients. | Zhiqiang Zhang Xiaoran Guo Kenneth K.W.To Zhen Chen Xiaona Fang Min Luo Chunling Ma Jianhua Xu Shirong Yan Liwu Fu | 2018 | Acta Pharmaceutica Sinica B2018，8，4： | 9 |
| 5 | Radiative transfer models(RTMs)for field phenotyping inversion of rice based on UAV hyperspectral remote sensing显示文摘The nondestructive and rapid acquisition of rice field phenotyping information is very important for the precision management of the rice growth process.In this research,the phenotyping information LAI(leaf area index),leaf chlorophyll content(C_(ab)),canopy water content(C_(w)),and dry matter content(C_(dm))of rice was inversed based on the hyperspectral remote sensing technology of an unmanned aerial vehicle(UAV).The improved Sobol global sensitivity analysis(GSA)method was used to analyze the input parameters of the PROSAIL model in the spectral band range of 400-1100 nm,which was obtained by hyperspectral remote sensing by the UAV.The results show that C_(ab) mainly affects the spectrum on 400-780 nm band,C_(dm) on 760-1000 nm band,C_(w) on 900-1100 nm band,and LAI on the entire band.The hyperspectral data of the 400-1100 nm band of the rice canopy were acquired by using the M600 UAV remote sensing platform,and the radiance calibration was converted to the canopy emission rate.In combination with the PROSAIL model,the particle swarm optimization algorithm was used to retrieve rice phenotyping information by constructing the cost function.The results showed the following:(1)an accuracy of R^(2)=0.833 and RMSE=0.0969,where RMSE denotes root-mean-square error,was obtained for C_(ab) retrieval;R^(2)=0.816 and RMSE=0.1012 for LAI inversion;R^(2)=0.793 and RMSE=0.1084 for C_(dm);and R^(2)=0.665 and RMSE=0.1325 for C_(w).The C_(w) inversion accuracy was not particularly high.(2)The same band will be affected by multiple parameters at the same time.(3)This study adopted the rice phenotyping information inversion method to expand the rice hyperspectral information acquisition field of a UAV based on the phenotypic information retrieval accuracy using a high level of field spectral radiometric accuracy.The inversion method featured a good mechanism,high universality,and easy implementation,which can provide a reference for nondestructive and rapid inversion of rice biochemical parameters using UAV hyperspectral remote sensing. | Yu Fenghua Xu Tongyu Du Wen Ma Hang Zhang Guosheng Chen Chunling | 2017 | International Journal of Agricultural and Biological Engineering2017，10，4： | 8 |
| 6 | Bioflocculant Produced by Klebsiella sp. MYC and Its Appli-cation in the Treatment of Oil-field Produced Water显示文摘Seventy-nine strains of bioflocculant-producing bacteria were isolated from 3 activated sludge samples. Among them, strain MYC was found to have the highest and stable flocculating rate for both kaolin clay suspension and oil-field produced water. The bacterial strain was identified as Klebsiella sp. MYC according to its morphological and biochemical characteristics and 16S rDNA sequence. The optimal medium for bioflocculant production by this bacterial strain was composed of cane sugar 20 g L -1, KH2PO4 2 g L -1, K2HPO4 5 g L -1, (NH4)2SO4 0.2 g [KG-*9]L -1, urea 0.5 g L -1 and yeast extract 0.5 g L -1, the initial pH being 5.5. When the suspension of kaolin clay was treated with 0.5% of Klebsiella sp. MYC culture broth, the flocculating rate reached more than 90.0% in the presence of 500 mg L -1 CaCl2, while the flocculating rate for oil-field produced water was near 80[KG-*3].0% in a pH range of 7.0-9.0 with the separation of oil and suspended particles from the oil-field produced water under similar conditions. The environment-friendly nature of the bioflocculant and high flocculating rate of the strain make the bioflocculant produced by Klebsiella sp. MYC an attractive bioflocculant in oil-field produced water treatment. | YUE Lixi MA Chunling CHI Zhenming | 2006 | Journal of Ocean University of China2006，5，4： | 7 |
| 7 | Amylase Production by the Marine Yeast Aureobasidium pullulans N13d显示文摘The marine yeast strain N13d, producing an extracellular amylase, was isolated from the deep sea sediments of the Pa-cific Ocean. This strain was identified to be Aureobasidium pullulans by 18S rRNA gene sequence analysis and routine yeast identi-fication methods. The optimal sea water medium for amylase production by this yeast strain was 1.0% peptone and 1.0% soluble starch with pH 4.0. The optimal conditions for amylase production by this yeast strain were with temperature 28 ℃, aeration rate 6 Lmin-1 and agitation speed 250 rmin-1. Under these conditions, 58.5 units of amylase activity per mg protein were produced within 56 h of fermentation. | LI Haifeng, CHI Zhenming *, WANG Xiaohong, and MA Chunling UNESCO Chinese Center of Marine Biotechnology, Ocean University of China, Qingdao 266003, P. R. China | 2007 | Journal of Ocean University of China2007，6，1： | 5 |
| 8 | Catalytic Enantioselective Simultaneous Control of Axial Chirality and Central Chirality in Allenes显示文摘 | Jianxin Dai Xinyu Duan Jing Zhou Chunling Fu Shengming Ma | 2018 | Chinese Journal of Chemistry2018，36，5： | 5 |
| 9 | Genome and transcriptome of Papaver somniferum Chinese landrace CHM indicates that massive genome expansion contributes to high benzylisoquinoline alkaloid biosynthesis显示文摘Opium poppy(Papaver somniferum)is a source of morphine,codeine,and semisynthetic derivatives,including oxycodone and naltrexone.Here,we report the de novo assembly and genomic analysis of P.somniferum traditional landrace‘Chinese Herbal Medicine’.Variations between the 2.62 Gb CHM genome and that of the previously sequenced high noscapine 1(HN1)variety were also explored.Among 79,668 protein-coding genes,we functionally annotated 88.9%,compared to 68.8%reported in the HN1 genome.Gene family and 4DTv comparative analyses with three other Papaveraceae species revealed that opium poppy underwent two whole-genome duplication(WGD)events.The first of these,in ancestral Ranunculales,expanded gene families related to characteristic secondary metabolite production and disease resistance.The more recent species-specific WGD mediated by transposable elements resulted in massive genome expansion.Genes carrying structural variations and large-effect variants associated with agronomically different phenotypes between CHM and HN1 that were identified through our transcriptomic comparison of multiple organs and developmental stages can enable the development of new varieties.These genomic and transcriptomic analyses will provide a valuable resource that informs future basic and agricultural studies of the opium poppy. | Li Pei Baishi Wang Jian Ye Xiaodi Hu Lihong Fu Kui Li Zhiyu Ni Zhenlong Wang Yujie Wei Luye Shi Ying Zhang Xue Bai Mengwan Jiang Shuhui Wang Chunling Ma Shujin Li Kaihui Liu Wanshui Li Bin Cong | 2021 | Horticulture Research2021，8，1： | 4 |
| 10 | A new Lactobacillus gasseri strain HMV18 inhibits the growth of pathogenic bacteria显示文摘To search for a new eco-friendly therapy for infectious disease caused by Escherichia coli,Staphylococcus aureus or Klebsiella oxytoca,we collected the vaginal swabs from healthy women,screened for Lactobacillus and found a strain repressing the growth of pathogenic bacteria.The new isolate was identified as L.gasseri by the colony morphology,Gram staining,biochemical reactions and confirmed by the 16 S rDNA sequencing.The HMV18 strain inhibited the growth of food-borne pathogens such as E.coli,S.aureus and K.oxytoca.The HMV18 strain was sensitive to penicillin,ampicillin,erythromycin,tetracycline and chloramphenicol.The HMV18 strain producedα-hemolysis.Pathological histology of the mice ileum showed that the mucosa,villi,lamina propria and crypt depth remained intact and there was no inflammation or hyperemia in the L.gasseri HMV18 gavaged group.L.gasseri HMV18 could not up-regulate inflammatory cytokines level of plasma.All the results suggested L.gasseri HMV18 is a candidate probiotic to be an additive for food preservation or drug to prevent food-borne diseases. | Xiang Gao Zixuan Wang Xiang Li Xiaoling Zhang Shengqiang Du Miaomiao Jia Dailun Hu Xianxian Jia Bin Cong Yan Zhang Chunling Ma Song Zhou Jun Zhang | 2022 | Food Science and Human Wellness2022，11，2： | 3 |
| 11 | Pore structures of fly ashes acticated by Ca(OH)2 and CaS04' 2H20显示文摘 | Ma Weiping Liu Chunling Brown Paul W | 1995 | Cement and Concrete Research1995，25，2： | 1 |
| 12 | Pore structures of fly ashes activated by Ca(OH)2 and CaSO4·2H2O显示文摘 | Ma Weiping Liu Chunling Brown P W | 1995 | Cement and Concrete Research1995，25，： | 1 |
| 13 | Rdh13 deficiency weakens carbon tetrachloride-induced liver injury by regulating Spotl4 and Cyp2e1 expression levels显示文摘Mitochondrion-localized retinol dehydrogenase 13 (Rdh13) is a short-chain dehydrogenase/reductase involved in vitamin A metabolism in both humans and mice. We previously generated Rdh13 knockout mice and showed that Rdh13 deficiency causes severe acute retinal light damage. In this study, considering that Rdh13 is highly expressed in mouse liver, we further evaluated the potential effect of Rdh13 on liver injury induced by carbon tetrachloride (CC14). Although Rdh13 deficiency showed no significant effect on liver histology and physiological functions under regular culture, the Rdh13^-/- mice displayed an attenuated response to CCl4-induced liver injury. Their livers also exhibited less histological changes and contained lower levels of liver-related metabolism enzymes compared with the livers of wild-type (WT) mice. Furthermore, the Rdhl3 1 mice had Rdh13 deficiency and thus their liver cells were protected from apoptosis, and the quantity of their proliferative cells became lower than that in WT after CC14 exposure. The ablation of Rdhl3 gene decreased the expression levels of thyroid hormone-inducible nuclear protein 14 (Spot14) and cytochrome P450 (Cyp2el) in the liver, especially after CC14 treatment for 48 h. These data suggested that the alleviated liver damage induced by CC14 in Rdh13^-/- mice was caused by Cyp2el enzymes, which promoted reductive CC14 metabolism by altering the status of thyroxine metabolism. This result further implicated Rdhl3 as a potential drug target in preventing chemically induced liver injury. | Xiaofang Cui Benting Ma Yan Wang Yan Chen Chunling Shen Ying Kuang Jian Fei Lungen Lu Zhugang Wang | 2019 | Frontiers of Medicine2019，13，1： | 1 |
| 14 | Blockade of KCa3.1 Ameliorates Renal Fibrosis Through the TGF-β1/Smad Pathway in Diabetic Mice显示文摘 | Chunling Huang Sylvie Shen Qing Ma Jason Chen Anthony Gill Carol A. Pollock Xin-Ming Chen | 2013 | Diabetes2013，，8： | 1 |
| 15 | Gorlos-phos for palladium-catalyzed borylation of aryl chlorides显示文摘 | LI Pengbin FU Chunling MA Shengming | 2014 | Org Biomol Chem2014，12，： | 1 |
| 16 | Purification and characterization of an alkaline protease from the marine aureobasidium pullulans for bioactive peptide production from different sources显示文摘 | Ma Chunling Ni Xiumei Chi Zhenming | 2007 | Marine bioteehnology2007，，9： | 1 |
| 17 | Raman spectroscopy of laser ablated BaTiO3/ YBa2Cu3O7-x thin films bilayer structure 显示文摘 | CUI Dafu LI Chunling MA Kun | 1996 | Appl Phys Lett1996，68，6： | 1 |
| 18 | Emotion Estimation And Reasoning Based on Affective Textual In- teraction显示文摘 | MA Chunling PRENDINGER H ISHIZUKA M | 2005 | Affective Computing and Intelligent Interac- tion2005，3784，： | 1 |
| 19 | Alkaline Protease Production by a Strain of Marine Yeasts显示文摘Yeast strain 10 with high yield of protease was isolated from sediments of saltern near Qingdao, China. The protease had the highest activity at pH 9.0 and 45 ℃. The optimal medium for the maximum alkaline protease production of strain 10 was 2.5 g soluble starch and 2.0 g NaNO3 in 100 mL seawater with initial pH 6.0. The optimal cultivation conditions for the maximum protease production were temperature 24.5 ℃, aeration rate 8.0 L min -1 and agitation speed 150 r min -1. Under the optimal conditions, 623.1 U mg -1 protein of alkaline protease was reached in the culture within 30 h of fermentation. | WANG Ping CHI Zhenming MA Chunling | 2006 | Journal of Ocean University of China2006，5，3： | 1 |
| 20 | Parallel Study on Potential and Existing Geographical Distribution of Haloxylon Dominated Desert Vegetation in China显示文摘By applying ARC/INFO (NT version) of the GIS software package , we extracted the existing geographicaldistribution ofHaloxylon dominated desertvegetationandproduced athematicmap ofgeographical distribution of theexisting Haloxylon dominated desert vegetation based on the newly published Vegetation Atlas of China;we defined the adaptiveparameter range ofgeographical and climate ofHaloxylon dominated desert vegetation to generate the potential geographical distribution map of Haloxylon dominated desert vegetation with thesupport of GREEN software. We then sliced and compared the existing and thepotential distribution maps. The results show that the potential geographical distribution areas of Haloxylon ammodendron and Haloxylon persicum dominated desert vegetation accord with the existing distribution areas in the administration division, and the topographic types in both the distribution areas are similar. However, the borders of different directions ofthe potential H. ammodendron dominated desert vegetation distribution has surpassed 0.4° to 5.9° of the existing borders. The borders of different directions of the potential H. persicum dominated desert vegetation has surpassed 0.9° to 3.3° of the existing borders. In China, the existing geographical distributionalarea ofH. ammodendron dominated desertvegetation accounts for 9.1% of the potential one in China and the proportion of the existing H. persicum dominated desert vegetation distribution area to the potential areais 34.1%. The result of comparison of the potential and the existing distribution areaof Haloxylon dominated desert vegetation can provide important scientific basisfor the recovery, reconstruction and introduction of Haloxylon dominated desertvegetation. | GUO Quanshui WANG Chunling TAN Deyuan MA Chao WANG Xiangfu HAO Jianxi HE Hongyan | 2006 | Chinese Forestry Science and Technology2006，5，2： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员