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| 1 | Consensus on the application of negative pressure wound therapy of diabetic foot wounds显示文摘Because China is becoming an aging society,the incidence of diabetes and diabetic foot have been increasing.Diabetic foot has become one of the main health-related killers due to its high disability and mortality rates.Negative pressure wound therapy(NPWT)is one of the most effective techniques for the treatment of diabetic foot wounds and great progress,both in terms of research and its clinical application,has been made in the last 20 years of its development.However,due to the complex pathogenesis and management of diabetic foot,irregular application of NPWT often leads to complications,such as infection,bleeding and necrosis,that seriously affect its treatment outcomes.In 2020,under the leadership of Burns,Trauma and Tissue Repair Committee of the Cross-Straits Medicine Exchange Association,the writing group for‘Consensus on the application of negative pressure wound therapy of diabetic foot wounds’was established with the participation of scholars from the specialized areas of burns,endocrinology,vascular surgery,orthopedics and wound repair.Drawing on evidence-based practice suggested by the latest clinical research,this consensus proposes the best clinical practice guidelines for the application and prognostic evaluation of NPWT for diabetic foot.The consensus aims to support the formation of standardized treatment schemes that clinicians can refer to when treating cases of diabetic foot. | Shizhao Ji Xiaobin Liu Jie Huang Junmin Bao Zhaohong Chen Chunmao Han Daifeng Hao Jingsong Hong Dahai Hu Yufeng Jiang Shang Ju Hongye Li Zongyu Li Guangping Liang Yan Liu Gaoxing Luo Guozhong Lv Xingwu Ran Zhongmin Shi Juyu Tang Aiping Wang Guangyi Wang Jiangning Wang Xin Wang Bing Wen Jun Wu Hailin Xu Maojin Xu Xiaofei Ye Liangxi Yuan Yi Zhang Shichu Xiao Zhaofan Xia | 2021 | Burns & Trauma2021，9，1： | 17 |
| 2 | Magmatic Hydrothermal Origin of the Wenyu Copper Polymetallic Deposit, Southern Lancangjiang Zone, SW China显示文摘The Wenyu copper polymetallic deposit,with proven reserves of about 0.23 Mt Cu,394 t Ag and0.04 Mt Pb,is located in the central part of the Lancangjiang volcanic rock belt(Fig.1a),which is one of the most potential copper polymetallic exploration areas in SW China.The Wenyu deposit is hosted in the Xiaodingxi Formation | YANG Yongfei FAN Wenyu LUO Maojin SHI Hongzhao | 2015 | Acta Geologica Sinica(English Edition)2015，89，5： | 2 |
| 3 | Diabetes mellitus and risk of pancreatic cancer: A meta-analysis of cohort studies显示文摘 | Qiwen Ben Maojin Xu Xiaoyan Ning Jun Liu Shangyou Hong Wen Huang Huagao Zhang Zhaoshen Li | 2011 | European Journal of Cancer2011，，13： | 2 |
| 4 | Mutual alignment errors due to wave-front aberrations in inter satellite laser communications 显示文摘 | Sun Jianfeng Liu Liren Yun Maojin | 2005 | ApplOpt2005，44，： | 1 |
| 5 | MEK2 is a prognostic marker and potential chemo-sensitizing target for glioma patients undergoing temozolomide treatment显示文摘尽管 temozolomide (TMZ ) 是为 glioblastoma 的首要的化学疗法的代理人,它经常由于药抵抗是非药品。克服 glioblastoma 房间的抵抗到 TMZ,为结果预言识别预示的标记并且开发敏化 chemo 代理人是必要的。这里, TMZ 抵抗、 TMZ 敏感的样品的基因表示侧面被 microarray 分析,和激活 mitogen 的蛋白质 kinase kinase 比较(MEK2 ) 2 在抵抗 glioma 房间然而并非在敏感肿瘤房间或非肿瘤纸巾明确地是 upregulated。而且,耐心的数据的全面分析表明 MEK2 表示的增加的水平响应 TMZ 治疗与 glioma 等级和更坏的预后的前进相关很好。而且,在 U251 glioma 房间线或 xenografted glioma 减少 MEK2 的水平通过调停 shRNA 的基因为击倒的禁止的房间增长建模并且向 TMZ 治疗提高了房间的敏感。从由即时 PCR 的 glioma 病人的肿瘤样品的进一步的分析显示增加的 MEK2 表示水平仔细与许多药抵抗基因的激活被联系。最后,在 MEK2 是在 vitro 的 silenced 以后,这些抵抗基因是 downregulated,建议导致 MEK2 的 chemo 抵抗的机制能被这些抵抗基因的 transcriptional 激活调停。一起,我们的数据显示 MEK2 的表示水平能为 glioma 化疗用作一个预示的标记并且 MEK2 对手能被用作 chemo-sensitizers 提高 TMZ 的治疗功效。 | Hua He Maojin Yao Wenhao Zhang Bangbao Tao Feili Liu Shu Li Yan Dong Chenran Zhang Yicheng Meng Yuxin Li Guohan Hu Chun Luo Hui Zong Yicheng Lu | 2016 | Cellular & Molecular Immunology2016，13，5： | 1 |
| 6 | Numerical simulation and fracture evaluation method of dual laterolog in organic shale显示文摘 | Tan Maojin Wang Peng Li Jun | 2014 | Journal of Applied Geophysics2014，，100： | 1 |
| 7 | Metastatic tumor to the iris and ciliary body as an initial sign of lung cancer: a case report显示文摘The most common sites of lung cancer metastases are pleura, bone, brain, pericardium and liver. 1 Tumor metastasis to the eye is a rare complication of lung cancer. Metastatic cancer to the ocular region most often involves the uveal tract, however, most uveal metastases occur in the posterior uvea, and iris metastases are relatively rare. We describe a patient with adenocarcinoma of the lung metastatic to the iris as the first clinical sign without symptoms of lung cancer.CASE REPORTIn September 2003, a 54-year-old man was presented at outpatient department of ophthalmology because of progressive blurred vision and discomfort in his left eye during the previous week. Ocular examination of the left showed the best-corrected visual acuity 0.4 and intraocular pressure of 34 mmHg. Slit lamp examination of the left eye showed a saddle-shaped yellowish tumor with prominent blood vessels involving the iris in the temporal quadrant and a dome-shaped yellow-brown mass at the inferior-temporal pupil margin (Fig. 1). Tyndall sign was ++ and moderate cells in the left anterior chamber. Brownish material and blood vessels were found in the inferior and temporal chamber angle gonioscopically. Visual acuity and slit lamp examination of the right eye were not significant. Ophthalmoscopy revealed the cup/disc ratio was 0.3 and 0.5 for the right and left eye respectively. The retinae of both eyes were otherwise within normal limits. Ultrasound biomicroscopy showed mass lesion in the iris of left eye. Ciliary body was also involved. He had no other systemic symptom and no history of systemic cancer. His father died of lung cancer; one of his brothers died of colon cancer; his son was diagnosed as brain tumor. Iris and ciliary body metastasis and secondary glaucoma of the left eye were diagnosed. | SUIRui-fang ZHAOJia-liang ZHANGShun-hua FENGRui-e CHENGGang-wei MAJian-min MAOJin | 2005 | Chinese Medical Journal2005，，13： | 1 |
| 8 | Highly birefringent photonic crystal fibers with flattened dispersion and low effective mode area显示文摘 | Liang Jian Yun Maojin Kong Weijin | 2011 | Optik-International Journal for Light and Electron Optics2011，122，23： | 1 |
| 9 | A noval wireline logs based approach for assessment of mineral concentrations in organicshale显示文摘 | Tan Maojin Zou Youlong Wang Xiaochang | 2014 | OilShale2014，31，2： | 1 |
| 10 | Mutual alignment errors due to wave-front aberrations in inter satellite laser communications 显示文摘 | Sun Jianfeng Liu Liren Yun Maojin | 2005 | ApplOpt2005，44，23： | 1 |
| 11 | Diabetes mellitus and risk of pancreatic cancer: A meta-analysis of cohort studies显示文摘 | Qiwen Ben Maojin Xu Xiaoyan Ning Jun Liu Shangyou Hong Wen Huang Huagao Zhang Zhaoshen Li | 2011 | European Journal of Cancer2011，，13： | 1 |
| 12 | Ablation of liver cancer cells in vitro by a plasma needle显示文摘 | Zhang Xianhui Li Maojin Zhou Rouli | 2008 | Applied Physics Letters2008，93，02： | 1 |
| 13 | A No-val Wireline Logs Based Approach for Assessment of Min-eral Concentrations in Organic Shale显示文摘 | TAN Maojin ZOU Youlong WANG Xiaochang | 2014 | Oil Shale2014，31，2： | 1 |
| 14 | Lycium ruthenicum Murr. treatment attenuates APP_(SWE)/PS1ΔE9 mouse model-like mitochondrial dysfunction in Slc25a46 knockout mouse model显示文摘Mitochondrial dysfunction is proposed to be substantially associated with ageing and ageing-related diseases like Alzheimer's disease(AD). However, it is unclear whether different mouse models with mitochondrialrelated diseases have similar changes in mitochondrial morphology of the same tissues. Moreover, whether similarities in mitochondrial morphology can be a suitable marker for screening and/or discovering mitochondrial-protective substances remains unknown. Mitochondria morphology in different tissues of a novel mitochondrial outer membrane protein Slc25a46 knockout mouse and a traditional APP_(SWE)/PS1ΔE9 transgenic mouse were examined using transmission electron microscope(TEM). Both young Slc25a46 knockout mice and aged APP_(SWE)/PS1ΔE9 mice models showed similar mitochondrial damage in cerebellum tissues. The results indicated that different mitochondrial-related diseases shared similar alteration and defects in mitochondrial morphology. Furthermore, Lycium ruthenicum Murr. extract, a bioactive food substance with cognition-improving property, could effectively improve muscle strength and increase body weight in the Slc25a46 knockout mice. These findings suggest that mitochondrial morphology defects in mice models, particularly in the mitochondrial compartment, represent a unified and effective marker for screening and validating natural product-derived functional substances with mitochondrial protective properties. It also holds potential application in mitochondrial-impaired senile neurodegenerative diseases, especially in AD. | Min Wang Tianxiong Xu Li Gao Chujun Huang Piao Xu Congcong Gong William Kwame Amakye Linfeng Liao Maojin Yao Jiaoyan Ren | 2023 | Food Science and Human Wellness2023，12，5： | 0 |
| 15 | Cellular origin of glioblastoma and its implication in precision therapy显示文摘Glioblastoma(GBM)is the most common malignant primary tumor in the central nervous system.Despite advances in neurosurgery,radiation therapy and chemotherapy,the median survival time of GBM patients is only 9 to 16 months.1 Therefore,GBM is considered one of the deadliest human cancers.In the past two decades,many efforts have been made by scientists and clinicians to develop new drugs to improve current therapies.Unfortunately,most efforts have not achieved long-term remissions in clinical trials,even though some of them are promising in animal models,making treatment options still limited. | Maojin Yao Shu Li Xiaojun Wu Shuo Diao Guoxin Zhang Hua He Liuguan Bian Yicheng Lu | 2018 | Cellular & Molecular Immunology2018，15，8： | 0 |
| 16 | Experimental models for cancer brain metastasis显示文摘Brain metastases are a leading cause of cancer-related mortality.However,progress in their treatment has been limited over the past decade,due to an incomplete understanding of the underlying biological mechanisms.Employing accurate in vitro and in vivo models to recapitulate the complexities of brain metastasis offers the most promising approach to unravel the intricate cellular and physiological processes involved.Here,we present a comprehensive review of the currently accessible models for studying brain metastasis.We introduce a diverse array of in vitro and in vivo models,including cultured cells using the Transwell system,organoids,microfluidic models,syngeneic models,xenograft models,and genetically engineered models.We have also provided a concise summary of the merits and limitations inherent to each model while identifying the optimal contexts for their effective utilization.This review serves as a comprehensive resource,aiding researchers in making well-informed decisions regarding model selection that align with specific research questions. | Zihao Liu Shanshan Dong Mengjie Liu Yuqiang Liu Zhiming Ye Jianhao Zeng Maojin Yao | 2024 | Cancer Pathogenesis and Therapy2024，2，1： | 0 |
| 17 | A Usable Selection Range Standard Based on Test Suite Reduction Algorithms显示文摘In this paper, we analyze the features and distinction of 6 classical algorithms: greedy algorithm (G), greedy evolution algorithm (GE), heuristics algorithm (H), greedy heuristic G (GRE), integer linear programming algorithm (ILP) and genetic algorithm (GA) to ensure the main influencing factors-the performance of algorithms and the running time of algorithms. What's more, we would not only present a research design that aims at gaining deeper understanding about the algorithm classification and its function as well as their distinction, but also make an empirical study in order to obtain a practical range standard that can guide the selection of reduction algorithms. When the size of a test object (product of test requirements and test cases) is smaller than 2000×2000, G algorithm is the commonly recommended algorithm. With the growth of test size, the usage of GE and GRE becomes more general. | MA Yanjun ZHAO Zhigang LIANG Yuchen YUN Maojin | 2010 | Wuhan University Journal of Natural Sciences2010，15，3： | 0 |
| 18 | Geological Features,Mineralization Types and Metallogenic Setting of the Phlaythong Large Iron Deposit,Southern Laos显示文摘The Phlaythong large iron deposit in Shampasak of southern Laos,is located in the Kon Tum microblock(Fig.1A),central-southern part of the Indo-China block,and the geographic coordinate of the central mining area is 14°43′04″N and 106°07′02″E.Intensive tectonic and magmatic activities of multiple periods developed in this region,especially in Mesozoic and Cenozoic,which are | LIU Shusheng FAN Wenyu LUO Maojin YANG Yongfei | 2015 | Acta Geologica Sinica(English Edition)2015，89，4： | 0 |
| 19 | Cultural Practices for Propagation of Spatholobus suberectus via Cutting into Polybags显示文摘In this paper,the propagation of Spatholobus suberectus Dunn.was optimized based on the research results conducted in propagation for many years and the actual need for the planting materials.According to the requirements of Good Agricultural Practices for Chinese Medicinal Drugs,cultural practices for propagation of S.suberectus were summed up and standardized,including the environmental requirements,land preparation,bed preparation,cutting of scions,cuttings treatment,cutting,management of cuttings at the nursery,bagged cuttings ready for transplanting,packing and handling,transportation,and preparation of records for archives. | Maojin YE Ribin HUANG Chunyun CHEN Dachang NING Su ZHANG Shufu CHEN Qingsong DONG | 2021 | Medicinal Plant2021，12，5： | 0 |
| 20 | Identification of the core promoter of STK11 gene and its transcriptional regulation by p53显示文摘Peutz-Jeghers syndrome (PJS) is an autosomal dominant disease characterized by mucocutaneous pigmentation and hamartomatous polyps. Most cases of PJS involve the inactivation of germline mutations in the serine/threonine kinase gene STK11 which is also known as LKB1. The function of STK11 was previously linked to the tumor suppressor p53 and was shown to activate the p53 target p21/ WAF1. Recently, STK11 was reported to be interacting with p53 physically in the nucleus and it can directly or indirectly phosphorylate p53. Here we characterized the 50-flanking region of human STK11 gene and identified a 161-bp fragment with promoter activity. Sequence analysis, mutagenesis and gel shift studies revealed a binding site of Sp1 and p53, which affects the promoter activity. Mutation analyses showed that this fragment was required for p53-mediated transcriptional activation. This transcriptional activation was further confirmed by real-time quantitative RT-PCR and Western blot analysis. Transient transfection of p53 expression plasmid into fetal liver cell lines increased STK11 mRNA and protein levels. In conclusion, our results reveal a new role for p53 in elevating STK11 gene expres- sion via a positive feedback pattern. | Maojin Yao Yongjun Wang Hongwei Shen Wenfeng Ning Jianguang Tang Xiangping Wang Jie Li Shiquang Zhou Xin Yi Ch-enjie Li Yi Chu Fei Wang Xiaoliu Shi | 2008 | Progress in Natural Science:Materials International2008，18，3： | 0 |
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