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| 1 | Recent progress of surface coating on cathode materials for high-performance lithium-ion batteries显示文摘Lithium-ion batteries (LIB) have received substantial attention in the last 10 years,as they offer great promise as power sources that can lead to the electric vehicle (EV) revolution in the next 5 years.Since the cathode serves as a key component in LIB,its properties significantly affect the performance of the whole system.Recently,the cathode surface modification based on coating technique has been widely employed to enhance the electrochemical performances by improving the material conductivity,stabilising the physical structure of materials,as well as preventing the reactions between the electrode and electrolyte.In this work,we reviewed the present of a number of promising cathode materials for Li-ion batteries.After that,we summarized the very recent research progress focusing on the surface coating strategies,mainly including the coating materials,the coating technologies,as well as the corresponding working mechanisms for cathodes.At last,the challenges faced and future guidelines for optimizing cathode materials are discussed.In this study,we propose that the structure of cathode is a crucial factor during the selection of coating materials and technologies. | Peiyuan Guan Lu Zhou Zhenlu Yu Yuandong Sun Yunjian Liu Feixiang Wu Yifeng Jiang Dewei Chu | 2020 | Journal of Energy Chemistry2020，29，4： | 28 |
| 2 | BMAL1 knockout macaque monkeys display reduced sleep and psychiatric disorders显示文摘Circadian disruption is a risk factor for metabolic, psychiatric and age-related disorders, and non-human primate models could help to develop therapeutic treatments. Here, we report the generation of BMAL1 knockout cynomolgus monkeys for circadian-related disorders by CRISPR/Cas9 editing of monkey embryos. These monkeys showed higher nocturnal locomotion and reduced sleep, which was further exacerbated by a constant light regimen. Physiological circadian disruption was reflected by the markedly dampened and arrhythmic blood hormonal levels. Furthermore, BMAL1-deficient monkeys exhibited anxiety and depression, consistent with their stably elevated blood cortisol, and defective sensory processing in auditory oddball tests found in schizophrenia patients. Ablation of BMAL1 up-regulated transcriptional programs toward inflammatory and stress responses, with transcription networks associated with human sleep deprivation, major depressive disorders, and aging. Thus, BMAL1 knockout monkeys are potentially useful for studying the physiological consequences of circadian disturbance, and for developing therapies for circadian and psychiatric disorders. | Peiyuan Qiu Jian Jiang Zhen Liu Yijun Cai Tao Huang Yan Wang Qiming Liu Yanhong Nie Fang Liu Jiumu Cheng Qing Li Yun-Chi Tang Mu-ming Poo Qiang Sun Hung-Chun Chang | 2019 | National Science Review2019，6，1： | 21 |
| 3 | Dynamic tubulation of mitochondria drives mitochondrial network formation显示文摘 | Chong Wang Wanqing Du Qian Peter Su Mingli Zhu Peiyuan Feng Ying Li Yichen Zhou Na Mi Yueyao Zhu Dong Jiang Senyan Zhang Zerui Zhang Yujie Sun Li Yu | 2015 | Cell Research2015，25，10： | 8 |
| 4 | Characteristics and genesis of the Feixianguan Formation oolitic shoal reservoir, Puguang gas field, Sichuan Basin, China显示文摘在在西南中国的东北四川盆的著名 Puguang gasfield 的更低的三叠纪的 Feixianguan 形成生产一座代表性的鲕状的水库,吗最大的采购水兵的 gasfield 到目前为止在中国是哪个(比 350 大的证明煤气的储备地在 2003 发现了??????????????楥楸湡畧湡????畐畧湡?? | Peiyuan CHEN Xiucheng TAN Huiting YANG Ming TANG Yiwei JIANG Xiuju JIN Yang YU | 2015 | Frontiers of Earth Science2015，9，1： | 7 |
| 5 | Genome-wide association study and transcriptome analysis reveal new QTL and candidate genes for nitrogen-deficiency tolerance in rice显示文摘The development of rice cultivars with improved nitrogen use efficiency(NUE)is desirable for sustainable agriculture.Achieving this goal depends in part on understanding how rice responds to low soil nitrogen(N)and identifying causative genes underlying this trait.To identify quantitative trait loci(QTL)or genes associated with low N response,we conducted a genome-wide association study(GWAS)using a diverse panel of 230 rice accessions and performed a transcriptomic investigation of rice accessions with differential responses to low N stress at two N levels.We detected 411 GWAS-associated genes in 5 QTL and 2722 differentially expressed genes in response to low N,of which 24 were identified by both methods and ranked according to gene annotations,literature queries,gene expression,and genetic diversity analysis.The large-scale datasets obtained from this study reveal low N-responsive characteristics and provide insights towards understanding the regulatory mechanisms of N-deficiency tolerance in rice,and the candidate genes or QTL would be valuable resources for increasing rice NUE via molecular biotechnology. | Qing Li Xueli Lu Changjian Wang Lan Shen Liping Dai Jinli He Long Yang Peiyuan Li Yifeng Hong Qiang Zhang Guojun Dong Jiang Hu Guangheng Zhang Deyong Ren Zhenyu Gao Longbiao Guo Qian Qian Li Zhu Dali Zeng | 2022 | The Crop Journal2022，10，4： | 3 |
| 6 | Effects of Angelica sinensis extracts on lipid oxidation in fish feeds and growth performance of juvenile Jian carp(Cyprinus carpio var. Jian)显示文摘The study was to explore the effect of the extracts of Angelica sinensis(EAs) on lipid oxidation in fish feeds compared with ethoxyquin(EQ) and the effect of dietary EAs on growth performance of carp(Cyprinus carpio var. Jian). Firstly, fish feeds were respectively added with EQ, and ethyl ether extract ethyl acetate extract(EAE), acetone extract, ethanol extract(EE) and aqueous extract(AQE) of Angelica sinensis, except for the control. The results showed that EAs and EQ inhibited lipid oxidation in fish feed(P < 0.05). Of all of the examined EAs, EAE showed the strongest protective effects against lipid oxidation(P < 0.05). Moreover, EAE at high concentrations showed a stronger effect on lipid oxidation compared with EQ(P < 0.05). Then, 7 experimental diets respectively supplemented with 0.0, 1.0, 2.0, 3.0, 4.0, 5.0 and 6.0 g/kg of EAE were fed to the respective treatment groups for 30 d. Four replicates were performed for each treatment group; 20 carp(mean weight: 12.10 ± 0.13 g) were in each replicate. The result indicated that dietary EAE improved the growth performance in carp(P < 0.05). The appropriate con centration of EAE for carp growth was estimated to be 3.643 g/kg diet. Thus, EAE could be used as a natural antioxidant in feeds for Jian carp. | Huatao Li Dandan Yang Zhihao Li Mingquan He Fengyi Li Jun Jiang Siyi Tang Peiyuan Peng Wenhao Du Yuting Ma Ying Liu | 2019 | Animal Nutrition2019，，1： | 2 |
| 7 | SCUBE2 mediates bone metastasis of luminal breast cancer by modulating immune-suppressive osteoblastic niches显示文摘Estrogen receptor (ER)-positive luminal breast cancer is a subtype with generally lower risk of metastasis to most distant organs. However, bone recurrence occurs preferentially in luminal breast cancer. The mechanisms of this subtype-specific organotropism remain elusive. Here we show that an ER-regulated secretory protein SCUBE2 contributes to bone tropism of luminal breast cancer. Single-cell RNA sequencing analysis reveals osteoblastic enrichment by SCUBE2 in early bone-metastatic niches. SCUBE2 facilitates release of tumor membrane-anchored SHH to activate Hedgehog signaling in mesenchymal stem cells, thus promoting osteoblast differentiation. Osteoblasts deposit collagens to suppress NK cells via the inhibitory LAIR1 signaling and promote tumor colonization. SCUBE2 expression and secretion are associated with osteoblast differentiation and bone metastasis in human tumors. Targeting Hedgehog signaling with Sonidegib and targeting SCUBE2 with a neutralizing antibody both effectively suppress bone metastasis in multiple metastasis models. Overall, our findings provide a mechanistic explanation for bone preference in luminal breast cancer metastasis and new approaches for metastasis treatment. | Qiuyao Wu Pu Tian Dasa He Zhenchang Jia Yunfei He Wenqian Luo Xianzhe Lv Yuan Wang Peiyuan Zhang Yajun Liang Wenjin Zhao Jun Qin Peng Su Yi-Zhou Jiang Zhi-Ming Shao Qifeng Yang Guohong Hu | 2023 | Cell Research2023，33，6： | 1 |
| 8 | Microscale methods to assemble mammalian cells into tissue-like structures显示文摘Different cell types make up tissues and organs hierarchically and communicate within a complex, three-dimensional (3D) en- vironment. The in vitro recapitulation of tissue-like structures is meaningful, not only for fundamental cell biology research, but also for tissue engineering (TE). Currently, TE research adopts either the top-down or bottom-up approach. The top-down approach involves defining the macroscopic tissue features using biomaterial scaffolds and seeding cells into these scaffolds. Conversely, the bottom-up approach aims at crafting small tissue building blocks with precision-engineered structural and functional microscale features, using physical and/or chemical approaches. The bottom-up strategy takes advantage of the repeating structural and functional units that facilitate cell-cell interactions and cultures multiple cells together as a functional unit of tissue. In this review, we focus on currently available microscale methods that can control mammalian cells to assemble into 3D tissue-like structures. | GONG PeiYuan ZHENG WenFu XIAO Dan JIANG XingYu | 2012 | Science China(Life Sciences)2012，55，10： | 1 |
| 9 | A Robust Conformer-Based Speech Recognition Model for Mandarin Air Traffic Control显示文摘This study aims to address the deviation in downstream tasks caused by inaccurate recognition results when applying Automatic Speech Recognition(ASR)technology in the Air Traffic Control(ATC)field.This paper presents a novel cascaded model architecture,namely Conformer-CTC/Attention-T5(CCAT),to build a highly accurate and robust ATC speech recognition model.To tackle the challenges posed by noise and fast speech rate in ATC,the Conformer model is employed to extract robust and discriminative speech representations from raw waveforms.On the decoding side,the Attention mechanism is integrated to facilitate precise alignment between input features and output characters.The Text-To-Text Transfer Transformer(T5)language model is also introduced to handle particular pronunciations and code-mixing issues,providing more accurate and concise textual output for downstream tasks.To enhance the model’s robustness,transfer learning and data augmentation techniques are utilized in the training strategy.The model’s performance is optimized by performing hyperparameter tunings,such as adjusting the number of attention heads,encoder layers,and the weights of the loss function.The experimental results demonstrate the significant contributions of data augmentation,hyperparameter tuning,and error correction models to the overall model performance.On the Our ATC Corpus dataset,the proposed model achieves a Character Error Rate(CER)of 3.44%,representing a 3.64%improvement compared to the baseline model.Moreover,the effectiveness of the proposed model is validated on two publicly available datasets.On the AISHELL-1 dataset,the CCAT model achieves a CER of 3.42%,showcasing a 1.23%improvement over the baseline model.Similarly,on the LibriSpeech dataset,the CCAT model achieves a Word Error Rate(WER)of 5.27%,demonstrating a performance improvement of 7.67%compared to the baseline model.Additionally,this paper proposes an evaluation criterion for assessing the robustness of ATC speech recognition systems.In robustness evaluation experiments based on this criterion,the proposed model demonstrates a performance improvement of 22%compared to the baseline model. | Peiyuan Jiang Weijun Pan Jian Zhang Teng Wang Junxiang Huang | 2023 | Computers, Materials & Continua2023，77，10： | 0 |
| 10 | Optical Spectra and Gain Properties of Ho^(3+)/Pr^(3+)Co-doped LiYF_4 Crystal显示文摘The LiYF4single crystals singly doped Ho3tand co-doped Ho3t,Pr3tions were grown by a modified Bridgman method.The JuddeOfelt strength parameters(U2,U4,U6)of Ho3twere calculated according to the absorption spectra and the JuddeOfelt theory,by which the radiative transition probabilities(A),fluorescence branching ratios(b)and radiative lifetime(srad)were obtained.The radiative lifetimes of5I6and5I7levels in Ho3t(1 mol%):LiYF4are 10.89 and 20.19 ms,respectively,while 9.77 and 18.50 ms in Ho3t/Pr3tdoped crystals.Hence,the sradof5I7level decreases significantly by introduction of Pr3tinto Ho3t:LiYF4crystal which is beneficial to the emission of 2.9 mm.The maximum emission cross section of Ho3t:LiYF4crystal located at2.05 mm calculated by McCumber theory is 0.51 10 20cm2which is compared with other crystals.The maximum emission cross section at 2948 nm in Ho3t/Pr3tco-doped LiYF4crystal obtained by Fuchtbauere Ladenburg theory is 0.68 10 20cm2,and is larger than the value of 0.53 10 20cm2in Ho3tsingly doped LiYF4crystal.Based on the absorption and emission cross section spectra,the gain cross section spectra were calculated.In the Ho3tions singly doped LiYF4crystal,the gain cross sections for 2.05 mm infrared emission becomes positive once the population inversion level reaches 30%.It means that the pump threshold for obtaining 2.05 mm laser is probably lower which is an advantage for Ho3t-doped LiYF42.05 mm infrared lasers.The calculated gain cross section for 2.9 mm mid-infrared emission does not become positive until the population inversion level reaches 40%in Ho3t/Pr3t:LiYF4crystal,but 50%in Ho3tsingly doped LiYF4crystal,indicating that a low pumping threshold is achieved for the Ho3t:5I6/5I7laser operation with the introduction of Pr3tions.It was also demonstrated that Pr3tion can deplete rapidly the lower laser Ho3t:5I7level and has influence on the Ho3t:5I6level.The Ho3t/Pr3t:LiYF4crystal may be a potential media for 2.9 mm mid-infrared laser. | Jiangtao Peng Haiping Xia Peiyuan Wang Haoyang Hu Lei Tang Yuepin Zhang Haochuan Jiang Baojiu Chen | 2014 | Journal of Materials Science & Technology2014，30，9： | 0 |
| 11 | The Protection and Inheritance of Historical Architecture and Cultural Heritage——The Cognitive Bias and Participation of Shanghai Citizen and Promotion Strategy显示文摘The historical architecture and cultural heritage is basic embodiments of the cultural representation, cultural character and cultural spirit of a city. Based on 954 effective questionnaires of Shanghai citizens, this paper analyzes the basic situation, cognitive bias and obstacles of the protection and inheritance of historical architecture and cultural heritage. For example, the contradiction between the objective demand of urban renewal and the protection of historical building has yet to be coordinated,and the legal system for the protection of heritage has yet to be improved. The ' protective destruction' of historical buildings and the over-commercialization are serious. Lack of public awareness, cultural selfconfidence,cultural feelings, cultural experience, lack of talent, and so on. Based on these obstacles,this paper explores the common participation of governments and enterprises, social groups and individuals from the macro-strategic level to enhance the quality of the protection and inheritance of historical architecture and cultural heritage. | Jiang Ling Li Peiyuan Fu Yuanyuan | 2018 | 国际文化管理2018，，1： | 0 |
| 12 | 2D graphene oxide-L-arginine-soybean lecithin nanogenerator for synergistic photothermal and NO gas therapy显示文摘Nitric oxide(NO) gas therapy has been regarded as a promising strategy for cancer treatment. However,its therapeutic efficiency is still unsatisfying due to the limitations of monotherapy. Previous preclinical and clinical studies have shown that combination therapy could significantly enhance therapeutic efficiency. Herein, a graphene oxide(GO)-L-arginine(L-Arg, a natural NO donor) hybrid nanogenerator is developed followed by surface functionalization of soybean lecithin(SL) for synergistic enhancement of cancer treatment through photothermal and gas therapy. The resultant GO-Arg-SL nanogenerator not only exhibited good biocompatibility and excellent endocytosis ability, but also exhibited excellent photothermal conversion capability and high sensitivity to release NO within tumor microenvironment via inducible NO synthase(i NOS) catalyzation. Moreover, the produced hyperthermia and intracellular NO could synergistically kill cancer cells both in vitro and in vivo. More importantly, this nanogenerator can efficiently eliminate tumor while inhibiting the tumor recurrence because of the immunogenic cell death(ICD) elicited by NIR laser-triggered hyperthermia and the immune response activation by massive NO generation. We envision that the GO-Arg-SL nanogenerator could provide a potential strategy for synergistic photothermal and gas therapy. | Haina Tian Jinyan Lin Fukai Zhu Jiaqi Li Suhua Jiang Liya Xie Yang Li Peiyuan Wang Zhenqing Hou Jinxiao Mi | 2023 | Chinese Chemical Letters2023，34，3： | 0 |
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