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| 1 | Comparative study on skin temperature response to menstruation at acupuncture points in healthy volunteers and primary dysmenorrhea patients显示文摘OBJECTIVE:To assess skin temperature response to menstruation at acupuncture points in primary dysmenorrhea(PD) patients and healthy volunteers so as to explore acupuncture point specificity in reflecting diseases in the light of skin temperature.METHODS:Fifty-two PD patients and 49 healthy volunteers were recruited.Skin temperature measurements were performed with a skin temperature assessment device at 10 points.Absolute difference between skin temperature of the same point on the left and right side is used as main outcome measure.RESULTS:On the first day of menstruation, when menstrual pain attacking in PD patients, a significant increase in skin temperature difference was detected at Taixi(KI 3) compared with the healthy group(P < 0.01).A significant reduction in skin temperature difference was detected at Taixi(KI 3) in the first day of menstruation compared with those values in the third day after menstruation(P < 0.01)in the healthy group.On the third day after menstruation, a significant reduction in skin temperature difference was found at Zhongdu(LR 6) in PD group compared with the healthy group(P < 0.05).No significant differences of skin temperature were detected at other points(P > 0.05).CONCLUSION:The skin temperature difference at menstruation-relevant points in PD patients did not all change significantly more than those in women without PD.Significant difference was only found in Taixi(KI 3), the Yuan-source point of Kidney meridian. | She Yanfen Ma Liangxiao Zhu Jiang Qi Conghui Wang Yanxia Tang Ling Li Chunhua Yuan Hongwen Liu Yuqi Song Jiashan | 2017 | Journal of Traditional Chinese Medicine2017，37，2： | 8 |
| 2 | Immunity-and-matrix-regulatory cells derived from human embryonic stem cells safely and effectively treat mouse lung injury and fibrosis显示文摘Lung injury and fibrosis represent the most significant outcomes of severe and acute lung disorders,including COVID-19.However,there are still no effective drugs to treat lung injury and fibrosis.In this study,we report the generation of clinical-grade human embryonic stem cells(hESCs)-derived immunity-and matrix-regulatory cells(IMRCs)produced under good manufacturing practice requirements,that can treat lung injury and fibrosis in vivo.We generate IMRCs by sequentially differentiating hESCs with serum-free reagents.IMRCs possess a unique gene expression profile distinct from that of umbilical cord mesenchymal stem cells(UCMSCs),such as higher expression levels of proliferative,immunomodulatory and anti-fibrotic genes.Moreover,intravenous delivery of IMRCs inhibits both pulmonary inflammation and fibrosis in mouse models of lung injury,and significantly improves the survival rate of the recipient mice in a dose-dependent manner,likely through paracrine regulatory mechanisms.IMRCs are superior to both primary UCMSCs and the FDA-approved drug pirfenidone,with an excellent efficacy and safety profile in mice and monkeys.In light of public health crises involving pneumonia,acute lung injury and acute respiratory distress syndrome,our findings suggest that IMRCs are ready for clinical trials on lung disorders. | Jun Wu Dingyun Song Zhongwen Li Baojie Guo Yani Xiao Wenjing Liu Lingmin Liang Chunjing Feng Tingting Gao Yanxia Chen Ying Li Zai Wang Jianyan Wen Shengnan Yang Peipei Liu Lei Wang Yukai Wang Liang Peng Glyn Nigel Stacey Zheng Hu Guihai Feng Wei Li Yan Huo Ronghua Jin Ng Shyh-Chang Qi Zhou Liu Wang Baoyang Hu Huaping Dai Jie Hao | 2020 | Cell Research2020，30，9： | 7 |
| 3 | Construction of cDNA library from iron-deficiency induced maize roots and screening and identification of iron-stress gene Fdr3显示文摘To isolate Fe-deficient related (Fdr) genes, an expression cDNA library of 4.5×105 pfu/μg has been constructed from maize roots in iron-stress. 6 clones have been screened from the cDNA library by differential hybridization screening. It is proved that an Fdr3 cDNA clone expressed stronger under iron-deficient condition than under iron-sufficient one by Northern blot and Western blot. | YIN Liping QI Xiaoting LIU Xianglin HUO Chunyan BAI Yanxia QIU Zesheng ZHANG Fusuo | 2000 | Chinese Science Bulletin2000，45，12： | 4 |
| 4 | Determination of Trace Copper (Ⅱ) in Water Samples by Kinetic-spectrophotometry显示文摘A new kinetic-spectrophotometric method is proposed for the determination of copper (Ⅱ). The method is based on the catalytic effect of copper (Ⅱ) on the oxidation of weak acid brilliant blue dye (RAWL) by hydrogen peroxide. The copper (Ⅱ) can be determined spectrophotometrically by measuring the decrease of absorbance of RAWL at λ = 626 nm using the fix-time method. The optimum reaction conditions are as follows: pH 7.20, buffer solution NaOH-KH2PO4, RAWL (200 mg L-1) 5.00 mL, H2O2 (30%) 0.50 mL, reaction temperature 80℃ and reaction time 20 min. The linear range of this method is between 0 μg L-1 and 12 μg L-1 and the limit of detection is 0.011 μg L-1, the relative standard deviation (RSD) in five replicate determinations for 2 and 8 μg L-1 copper (Ⅱ) are 3.2% and 2.3%, respectively. Twenty ions do not interfere in the determination of copper (Ⅱ). The method has been applied satisfactorily to the determination of copper (Ⅱ) in freshwater samples (tap water and Yellow River water from Lijin, Shandong, China) and seawater samples (from the South China Sea), the recovery rates are 98.0%, 102.5% and 96.0%, respectively. | QI Yanxia JI Hongwei XIN Huizhen LIU Li | 2007 | Journal of Ocean University of China2007，6，2： | 3 |
| 5 | Measurement of Trace Manganese(Ⅱ) by the Catalytic Kinetic Spectrophotometric Method显示文摘A new kinetic spectrophotometric method is developed for the measurement of manganese(Ⅱ) in water. The method is based on the catalytic effect of manganese(Ⅱ) with the oxidation of weak acid brilliant blue dye(RAWL) by KIO4 using the Nitrilo triacetic acid(NTA) as an activation reagent. The optimum conditions obtained are 40 mgL-1 RAWL,1×10-4molL-1 KIO4,2×10-4 molL-1 Nitrilo triacetic acid(NTA),pH = 5.8,the reaction time of 3.00 min and the temperature of 20.0 ℃. Under the optimum conditions,the proposed method allows the measurement of manganese(Ⅱ) in a range of 0-50.0 ng mL-1 and with a detection limit of down to 0.158 ng mL-1. The recovery efficiency in measuring the standard manganese(Ⅱ) solution is in a range of 98.5%-102%,and the RSD is in a range of 0.76%-1.25%. The new method has been successfully applied to the measurement of manganese(Ⅱ) in both fresh water and seawater samples with satisfying results. Moreover,few cations and anions interfere with the measurement of manganese(Ⅱ). Compared with other kinetic catalytic methods and instrumental methods,the proposed method shows fairly good selectivity and sensitivity,low cost,cheapness,low detection limit and rapidity. It can be applied on boats easily. | JI Hongwei SHA Yuanyuan XIN Huizhen QI Yanxia | 2009 | Journal of Ocean University of China2009，8，2： | 2 |
| 6 | Green synthesis of graphene nanosheets/ZnO composites and electrochemical properties显示文摘 | Jun Wang Zan Gao Zhanshuang Li Bin Wang Yanxia Yan Qi Liu Tom Mann Milin Zhang Zhaohua Jiang | 2011 | Journal of Solid State Chemistry2011，，： | 1 |
| 7 | Dynamic Characteristics and Influencing Factors of Groundwater Level in Qianyang County显示文摘The dynamic characteristics and influencing factors of groundwater level in Qianyang County were analyzed.The results showed that in the south bank of the Qianhe River,the change of groundwater level was mainly affected by precipitation,and the response of the groundwater level to the change of precipitation was one year later.The groundwater level presented a downward trend on the whole.In the north bank of the Qianhe River,the supply source of the groundwater level included precipitation and hydrology,and the groundwater level showed a rising trend on the whole.In the plain area,there was a sudden change in the groundwater level under the control of human activities.In a word,the main factors influencing the groundwater level in various geological conditions were different,so there were great differences between various regions in the dynamic characteristics of the groundwater level in Qianyang County. | Zhao Dan Zhou Qi Jing Yanxia | 2016 | Meteorological and Environmental Research2016，7，4： | 1 |
| 8 | Highly Efficient Heavy-Metal-Ion Removal from Shellfish Processing Liquid with Low Protein and Polysaccharide Loss by Hybrid Mesoporous Silica Diol-APDC-SBA15显示文摘Heavy metal ions in shellfish products are harmful to human health,and their removal with low nutrient loss remains challenging.Herein,a new type of mesoporous silica(SBA15),modified internally with ammonium pyrrolidine dithiocarbamate(APDC)and externally with alkyl-diol groups,which was named as Diol-APDC-SBA15,was successfully developed and characterized by powder X-ray diffraction patterns,nitrogen adsorption,and Fourier transform infrared spectroscopy.The solutions with lead,chromium,cadmium,and copper were used to investigate the adsorption capacity of Diol-APDC-SBA15.Diol-APDC-SBA15 was adopted to remove heavy metals from cooking liquids of clams(Ruditapes philippinarum),hydrolysate liquids of oysters(Ostrea gigas Thunberg),and polysaccharide solution from the cooking liquid of R.philippinarum.The efficiencies of removing heavy metal ions and the loss rates of proteins and polysaccharides were examined.The results showed that the adsorption capacities of Diol-APDCSBA15 for Pb,Cr,Cd,and Cu in standard heavy-metal solutions were 161.4,166.1,29.6,and 60.2mgg^(−1),respectively.The removal efficiency of Diol-APDC-SBA15 for Pb in the three shellfish processing liquids ranged from 60.5%to 99.6%.The Cr removal efficiency was above 99.9%in the oyster hydrolysate liquid.Meanwhile,the percentages of polysaccharide loss were 5.5%and 3.7%in the cooking liquid of clam and polysaccharide solution,respectively,and the protein loss was 1.2%in the oyster hydrolysate liquid.Therefore,the Diol-APDC-SBA15 material exhibits a great potential application in the removal of heavy metals from shellfish processing liquids with low losses of proteins and polysaccharides. | QI Yanxia SONG Yang LIU Chang QI Shizhe WANG Haibo CAO Jijuan ZHAO Qiancheng | 2023 | Journal of Ocean University of China2023，22，1： | 1 |
| 9 | Brightness Temperature Model of Sea Foam Layer at L-band显示文摘Permittivity of a sea foam layer is very important in investigating ocean brightness temperature model. At microwave frequency, the Rayleigh method is developed to estimate the effective permittivity of the sea foam layer. To simplify the tedious calculation of sea foam effective permittivity at L band(1.4 GHz), Pade' approximation is adopted to fit the sea foam effective permittivity computed by the Rayleigh method. With this fitting formula, a new brightness temperature model of sea foam layer defined by certain geophysical parameters, such as air volume fraction(AVF), sea surface temperature(SST), sea surface salinity(SSS) and thickness of foam layer d, is given. Furthermore, the sensitivities of the brightness temperature model to SST, SSS, d and AVF of a sea foam layer at L band are discussed. The sensitivities are ranked from most to least in the order:(1) d;(2) AVF;(3) SSS;(4) SST. This result indicates that the measurement errors of d and AVF have significant impacts on the retrievals of SSS and SST. With the experimental brightness temperature data, the SSS and AFV are retrieved by cost function. | LIU Shubo JIA Yanxia QI Zhen WEI Enbo | 2015 | Journal of Ocean University of China2015，14，1： | 1 |
| 10 | Myocardial Fibrosis in the Pathogenesis, Diagnosis, and Treatment of Hypertrophic Cardiomyopathy显示文摘Hypertrophic cardiomyopathy(HCM)is a type of hereditary cardiomyopathy caused by gene mutation.Its histological features include cardiomyocyte hypertrophy and disarray as well as myocardial fi brosis.Gene mutation,abnormal signal transduction,and abnormal energy metabolism are considered the main mechanisms of myocardial fi brosis.There is a strong correlation between myocardial fi brosis and the occurrence,development,and prognosis of HCM.We review the application of myocardial fi brosis in the diagnosis and treatment of HCM,focusing on research progress and the application of magnetic resonance imaging on the basis of the characteristics of fi brosis in the diagnosis and prognosis of HCM. | Zeyi Cheng Miaomiao Qi Chengyuan Zhang Yanxia Mao | 2021 | Cardiovascular Innovations and Applications2021，，2： | 1 |
| 11 | In Situ High-Temperature Reaction-Induced Local Structural Dynamic Evolution of Single-Atom Pt on Oxide Support显示文摘The dynamic evolution of active site coordination structure during a high-temperature reaction is critically significant but often difficult for the research of efficient single-atom catalysts(SACs).Herein,we for the first time report the in situ activation behaviors of the local coordination structure of Pt single atoms(Pt_(1))during the high-temperature oxidation of light alkanes.The distinctly enhanced activity of the catalyst is attributed to the in situ evolved Pt_(1)−oxygen vacancy(Pt_(1)−OV)combination ensemble as an efficient and stable active site.Theoretical calculations reveal that the lattice oxygen adjacent to Pt_(1)and the H dissociated from CH4 constitute the lattice hydroxyl,which is the initial step in the formation of the Pt_(1)−OV combination.Pt_(1)and nearby unsaturated Mn can donate the charge back to O−O to promote the dissociation of O_(2).This work provides molecular-level insight into the in situ reaction-induced evolution of a single-atom coordination environment for designing efficient SACs under harsh conditions. | Dongxu Yan Yanxia Gao Ming-Yu Qi Hongpeng Jia Yi-Jun Xu | 2023 | Precision Chemistry2023，1，5： | 0 |
| 12 | Influence of specific speed on hydraulic performances and pressure fluctuations in mixed-flow pumps显示文摘A series of steady and unsteady numerical calculations of the internal flow in mixed-flow pumps with three different specific speeds were carried out based on the N-S equation coupled with the standard k-εturbulence model under different operating conditions to investigate the relationship between the impeller specific speed and the pump performance as well as pressure pulsations.Meanwhile,the pump performance and pressure pulsations inside the mixed-flow pump with three different specific speeds were also analyzed and compared with the corresponding test data.From the results,the averaged deviations between the predicted and tested head among different impellers are below 5%,and with respect to the equivalent impeller specific speeds of 280 and 260,the values are 4.30%and 3.69%,respectively.For all the impeller schemes,the best efficiency point of the mixed-flow pump is found at the flow rate of 1.2 Q_(d) and the higher head deviation occurs at lower flow rates.Especially,it can be found that the specific speed has a slight effect on the pressure fluctuation in the impellers.Eventually,it is determined that the pump performance curves calculated by numerical simu-lations have good agreement with the relevant experimental results,which verifies that the numerical methods used in the present study are accurate to a certain extent.Furthermore,the results also provide some references to the pressure pulsation analysis and the performance improvement of the mixed-flow pump design. | FU Yanxia JIA Qi SHEN Yang PACE Giovanni | 2023 | 排灌机械工程学报2023，41，10： | 0 |
| 13 | Genome-wide analyses of nonsyndromic cleft lip with or without palate identify 20 new risk loci in the Chinese Han population显示文摘Orofacial clefts(OFCs),particularly cleft lip with or without cleft palate(CL/P)and cleft palate only(CPO),are among the most common birth defects in humans(Mossey et al.,2009;Dixon et al.,2011).The birth prevalence rate of OFCs in China is reported to be as high as 1.66 per thousand newborns. | Bao Li Liang Yong Yafen Yu Yanqin Yu Qi Zhen Huiyao Ge Yiwen Mao Weiwei Chen Yanxia Yu Yirui Wang Zhuo Li Wencheng Fan Chang Zhang Xia Hu Ruixue Zhang Lu Cao Hao Liu Zhuan Bian Miao He Liangdan Sun | 2022 | Journal of Genetics and Genomics2022，49，9： | 0 |
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