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| 1 | Application of Traditional Chinese Medicine injection in treatment of primary liver cancer:a review显示文摘OBJECTIVE:To investigate the application of Traditional Chinese Medicine Injections(TCMIs) for treatment of primary liver cancer(PLC).METHODS:A literature review was conducted using PubMed/Medline,Cochrane Library Controlled Clinical Trials Database,China National Knowledge Infrastructure(CNKI),China Scientific Journal Database(CSJD) and China Biology Medicine(CBM).Online websites including journal websites and databases of ongoing trials,as well as some Traditional Chinese Medicine journals that are not indexed in the electronic databases were also searched.RESULTS:The literature review showed that TCMIs as adjunctive medication for the treatment of PLC could regulate patient immunity,reduce bone marrow suppression,relieve clinical symptoms,and improve quality of life,as well as control disease progression and prolong survival time.CONCLUSION:Within the limitations of this review,we conclude that application of TCMIs as adjunctive medication may provide benefits for patients with PLC.Further large,high-quality trials are warranted. | Mouduo Li Cuixia Qiao Liping Qin Junyong Zhang Changquan Ling | 2012 | Journal of Traditional Chinese Medicine2012，32，3： | 22 |
| 2 | Chemical characteristics of fine particles and their impact on visibility impairment in Shanghai based on a 1-year period observation显示文摘In this work, a one-year observation focusing on high time resolution characteristics of components in fine particles was conducted at an urban site in Shanghai. Contributions of different components on visibility impairment were also studied. Our research indicates that the major components of PM_(2.5) in Shanghai are water-soluble inorganic ions and carbonaceous aerosol, accounting for about 60% and 30% respectively. Higher concentrations of sulfate(SO42-) and organic carbon(OC) in PM_(2.5) occurred in fall and summer, while higher concentrations of nitrate(NO_3^-) were observed in winter and spring. The mass concentrations of Cl^- and K^+ were higher in winter. Moreover, NO_3^- increased significantly during PM_(2.5) pollution episodes. The high values observed for the sulfate oxidizing rate(SOR), nitrate oxidizing rate(NOR) and secondary organic carbon(SOC) in OC indicate that photochemical reactions were quite active in Shanghai. The IMPROVE(Interagency Monitoring of Protected Visual Environments) formula was used in this study to investigate the contributions of individual PM_(2.5) chemical components to the light extinction efficient in Shanghai. Both NH_4NO_3 and(NH_4)_2SO_4 had close relationships with visibility impairment in Shanghai. Our results show that the reduction of anthropogenic SO_2, NO_x and NH_3 would have a significant effect on the improvement of air quality and visibility in Shanghai. | Min Zhou Liping Qiao Shuhui Zhu Li Li Shengrong Lou Hongli Wang Qian Wang Shikang Tao Cheng Huang Changhong Chen | 2016 | Journal of Environmental Sciences2016，28，10： | 22 |
| 3 | Diagnostic Values of Vascular Endothelial Growth Factor and Epidermal Growth Factor Receptor for Benign and Malignant Hydrothorax显示文摘 | Yan Gu Min Zhang Guo-Hua Li Jun-Zhen Gao Liping Guo Xiao-Juan Qiao Li-Hong Wang Lan He Mei-Ling Wang Li Yan Xiu-Hua Fu | 2015 | Chinese Medical Journal2015，，3： | 19 |
| 4 | Chemical and optical properties of aerosols and their interrelationship in winter in the megacity Shanghai of China显示文摘A field campaign on air quality was carried out in Shanghai in winter of 2012. The concentrations of NO, NO2, NOx, SO2, CO, and PM2.5increased during haze formation. The average masses of SO42-, NO3-and NH4+were 10.3, 11.7 and 6.7 μg/m3 during the haze episodes, which exceeded the average(9.2, 7.9, and 3.4 μg/m3) of these components in the non-haze days. The mean values for the aerosol scattering coefficient(b sp), aerosol absorption coefficient(b ap) and single scattering albedo(SSA) were 288.7, 27.7 and0.91 Mm-1, respectively. A bi-peak distribution was observed for the mass concentrations of CO, NO, NO2, and NOx. More sulfate was produced during daytime than that in the evening due to photochemical reactions. The mass concentration of NH4+achieved a small peak at noontime. NO3-showed lower concentrations in the afternoon and higher concentrations in the early morning. There were obvious bi-peak diurnal patterns for b sp and b ap as well as SSA. b sp and b ap showed a positive correlation with PM2.5mass concentration.(NH4)2SO4, NH4NO3, organic mass, elemental carbon and coarse mass accounted for 21.7%, 19.3%, 31.0%, 9.3% and 12.3% of the total extinction coefficient during non-haze days, and 25.6%, 24.3%, 30.1%, 8.1% and 8.2% during hazy days. Organic matter was the largest contributor to light extinction. The contribution proportions of ammonium sulfate and ammonium nitrate to light extinction were significantly higher during the hazy time than during the non-haze days. | Tingting Han Liping Qiao Min Zhou Yu Qu Jianfei Du Xingang Liu Shengrong Lou Changhong Chen Hongli Wang Fang Zhang Qing Yu Qiong Wu | 2015 | Journal of Environmental Sciences2015，27，1： | 14 |
| 5 | The long-term prediction of the oil-contaminated water from the Sanchi collision in the East China Sea显示文摘The condensate and bunker oil leaked from the Sanchi collision would cause a persistent impact on marine ecosystems in the surrounding areas. The long-term prediction for the distribution of the oil-polluted water and the information for the most affected regions would provide valuable information for the oceanic environment protection and pollution assessment. Based on the operational forecast system developed by the First Institute of Oceanography, State Oceanic Administration, we precisely predicted the drifting path of the oil tanker Sanchi after its collision. Trajectories of virtual oil particles show that the oil leaked from the Sanchi after it sank is mainly transported to the northeastern part of the sink location, and quickly goes to the open ocean along with the Kuroshio. Risk probability analysis based on the outcomes from the operational forecast system for years 2009 to2017 shows that the most affected area is at the northeast of the sink location. | YIN Liping ZHANG Min ZHANG Yuanling QIAO Fangli | 2018 | Acta Oceanologica Sinica2018，37，3： | 9 |
| 6 | Tumor-expressed B7-H3 mediates the inhibition of antitumor T-cell functions in ovarian cancer insensitive to PD-1 blockade therapy显示文摘Although PD-L1/PD-1 blockade therapy has been approved to treat many types of cancers,the majority of patients with solid tumors do not respond well,but the underlying reason remains unclear.Here,we studied ovarian cancer(OvCa),a tumor type generally resistant to current immunotherapies,to investigate PD-1-independent immunosuppression.We found that PD-L1 was not highly expressed in the tumor microenvironment(TME)of human OvCa.Instead,B7-H3,another checkpoint molecule,was highly expressed by both tumor cells and tumor-infiltrating antigen-presenting cells(APCs),which correlated with T-cell exhaustion in patients.Using ID8 OvCa mouse models,we found that B7-H3 expressed on tumor cells,but not host cells,had a dominant role in suppressing antitumor immunity.Therapeutically,B7-H3 blockade,but not PD-1 blockade,prolonged the survival of ID8 tumorbearing mice.Collectively,our results demonstrate that tumor-expressed B7-H3 inhibits the function of CD8^(+)T cells and suggest that B7-H3 may be a target in patients who are not responsive to PD-L1/PD-1 inhibition,particularly OvCa patients. | Dongli Cai Jiaming Li Dingfeng Liu Shanjuan Hong Qin Qiao Qinli Sun Pingping Li Nanan Lyu Tiantian Sun Shan Xie Li Guo Ling Ni Liping Jin Chen Dong | 2020 | Cellular & Molecular Immunology2020，17，3： | 8 |
| 7 | Do vehicular emissions dominate the source of C6–C8 aromatics in the megacity Shanghai of eastern China?显示文摘The characteristic ratios of volatile organic compounds(VOCs) to i-pentane, the indicator of vehicular emissions, were employed to apportion the vehicular and non-vehicular contributions to reactive species in urban Shanghai. Two kinds of tunnel experiments, one tunnel with more than 90% light duty gasoline vehicles and the other with more than 60% light duty diesel vehicles, were carried out to study the characteristic ratios of vehicle-related emissions from December 2009 to January 2010. Based on the experiments, the characteristic ratios of C6–C8aromatics to i-pentane of vehicular emissions were 0.53 ± 0.08(benzene), 0.70 ± 0.12(toluene),0.41 ± 0.09(m,p-xylenes), 0.16 ± 0.04(o-xylene), 0.023 ± 0.011(styrene), and 0.15 ± 0.02(ethylbenzene), respectively. The source apportionment results showed that around 23.3% of C6–C8 aromatics in urban Shanghai were from vehicular emissions, which meant that the non-vehicular emissions had more importance. These findings suggested that emission control of non-vehicular sources, i.e. industrial emissions, should also receive attention in addition to the control of vehicle-related emissions in Shanghai. The chemical removal of VOCs during the transport from emissions to the receptor site had a large impact on the apportionment results. Generally, the overestimation of vehicular contributions would occur when the VOC reaction rate constant with OH radicals(k OH) was larger than that of the vehicular indicator, while for species with smaller k OH than the vehicular indicator, the vehicular contribution would be underestimated by the method of characteristic ratios. | Hongli Wang Qian Wang Jianmin Chen Changhong Chen Cheng Huang Liping Qiao Shengrong Lou Jun Lu | 2015 | Journal of Environmental Sciences2015，27，1： | 7 |
| 8 | Genetic analysis of yield and fiber quality traits in upland cotton(Gossypium hirsutum L.) cultivated in different ecological regions of China显示文摘Background:Cotton is an important fiber crop worldwide.The yield potential of current genotypes of cotton can be exploited through hybridization.However,to develop superior hybrids with high yield and fiber quality traits,information of genetic control of traits is prerequisite.Therefore,genetic analysis plays pivotal role in plant breeding.Results:In present study,North Carolina II mating design was used to cross 5 female parents with 6 male parents to produce 30 intraspecific F1cotton hybrids.All plant materials were tested in three different ecological regions of China during the year of 2016-2017.Additive-dominance-environment(ADE)genetic model was used to estimate the genetic effects and genotypic and phenotypic correlation of yield and fiber quality traits.Results showed that yield traits except lint percentage were mainly controlled by genetic and environment interaction effects,whereas lint percentage and fiber quality traits were determined by main genetic effects.Moreover,dominant and additiveen vironine nt in teraction effects had more influence on yield traits,whereas additive and domi nance-e nviron ment interaction effects were found to be predominant for fiber traits.Broad-sense and its interaction heritability were significant for all yield and most of fiber quality traits.Narrow-sense and its interaction heritability were non-significant for boll number and seed cotton yield.Correlation analysis indicated that seed cotton yield had significant positive correlation with other yield attributes and non-significant with fiber quality traits.All fiber quality traits had signiflcant positive correlation with each other except micronaire.Conclusions:Results of current study provide important information about genetic control of yield and fiber quality traits.Further,this study identified that parental lines,e.g.,SJ48-1,ZB-1,851-2,and DT-8 can be utilized to improve yield and fiber quality traits in cotton. | SHAHZAD Kashif LI Xue QI Tingxiang GUO Liping TANG Huini ZHANG Xuexian WANG Hailin ZHANG Meng ZHANG Bingbing QIAO Xiuqin XING Chaozhu WU Jianyong | 2019 | Journal of Cotton Research2019，2，2： | 5 |
| 9 | Visualization of aging-associated chromatin alterations with an engineered TALE system显示文摘在实时房间的特定的 genomic loci 的可视化在多样的生物过程期间是为在染色质建筑学的动态变化的调查的一个前提,例如细胞的老化。然而,当前的精确 genomic 成像方法被缺乏妨碍荧光灯有高特性和 signal-to-noise 的探针形成对照。我们发现那常规抄写像使活跃之物的受动器(故事) 趋于形成蛋白质总数,从而在成像应用程序损害他们的性能。通过屏蔽,我们发现有故事的那熔化 thioredoxin 阻止了总数形成,开基于故事的 genomic 成像的完整的力量。用熔化 thioredoxin 的故事(TTALE ) ,我们在各种各样的 genomic loci 完成了高质量的成像并且观察联系老化(epi ) 在在人和老鼠早衰模型的 telomeres 和着丝点的 genomic 改变。重要地,我们鉴别 ribosomal DNA 的摩擦为人的老化作为一个分子的标记重复。我们的学习为精确在 vitro 并且在 vivo 监视染色质动力学建立一个简单、柔韧的成像方法。 | Ruotong Ren Liping Deng Yanhong Xue Keiichiro Suzuki Weiqi Zhang Yang Yu Jun Wu Liang Sun Xiaojun Gong Huiqin Luan Fan Yang Zhenyu Ju Xiaoqing Ren Si Wang Hong Tang Lingling Geng Weizhou Zhang Jian Li Jie Qiao Tao Xu Jing Qu Guang-Hui Liu | 2017 | Cell Research2017，27，4： | 4 |
| 10 | Strain effects on valence bands of wurtzite ZnO显示文摘Based on the k.p theory of Luttinger-Kohn and Bir-Pikus,analytical E-k solutions for the valence band of strained wurtzite ZnO materials are obtained.Strain effects on valence band edges and hole effective masses in strained wurtzite ZnO materials are also discussed.In comparison with unstrained ZnO materials,apparent movement of valence band edges such as 'light hole band','heavy hole band' and 'crystal splitting band' at Γ point is found in strained wurtzite ZnO materials.Moreover,effective masses of 'light hole band','heavy hole band' and 'crystal splitting band' for strained wurtzite ZnO materials as the function of stress are given.The analytical results can provide a theoretical foundation for the understanding of physics of strained ZnO materials and its applications with the framework for an effective mass theory. | QIAO LiPing CHAI ChangChun JIN Zhao YANG YinTang MA ZhenYang | 2013 | Science China(Physics,Mechanics & Astronomy)2013，56，9： | 3 |
| 11 | Genome-wide analysis of Rf-PPR-like(RFL)genes and a new InDel marker development for Rf1 gene in cytoplasmic male sterile CMS-D2 Upland cotton显示文摘Background: Cytoplasmic male sterility in flowering plants is a convenient way to use heterosis via hybrid breeding and may be restored by nuclear restorer-of-fertility(Rf) genes. In most cases, Rf genes encoded pentatricopeptide repeat(PPR) proteins and several Rf genes are present in clusters of similar Rf-PPR-like(RFL) genes. However, the Rf genes in cotton were not fully characterized until now.Results: In total, 35 RFL genes were identified in G. hirsutum, 16 in G. arboreum, and 24 in G. raimondii. Additionally,four RFL-rich regions were identified; the RFL-rich region in Gh_D05 is the probable location of Rf-PPR genes in cotton and will be studied further in the future. Furthermore, an insertion sequence was identified in the promoter sequence of Gh_D05 G3392 gene in the restorer line, as compared with the CMS-D2 line and maintainer lines. An InDel-R marker was then developed and could be used to distinguish the restorer line carrying Rfl from other genotypes without the Rf1 allele.Conclusion: In this study, genome-wide identification and analysis of RFL genes have identified the candidate Rf-PPR genes for CMS in Gossypium. The identification and analysis of RFL genes and sequence variation analysis will be useful for cloning Rf genes in the future and also for three-line hybrid breeding in cotton. | ZHANG Bingbing ZHANG Xuexian GUO Liping QI Tingxiang WANG Hailin TANG Huini QIAO Xiuqin SHAHZAD Kashif XING Chaozhu WU Jianyong | 2018 | Journal of Cotton Research2018，1，3： | 3 |
| 12 | Effect of UV-C treatments on phenolic compounds and antioxidant capacity of minimally processed Satsuma mandarin during refrigerated storage显示文摘 | Yan Shen Yujing Sun Liping Qiao Jianchu Chen Donghong Liu Xingqian Ye | 2013 | Postharvest Biology and Technology2013，，： | 2 |
| 13 | 2D-ultrathin MXene/DOXjade platform for iron chelation chemo-photothermal therapy显示文摘An increased demand for iron is a hallmark of cancer cells and is thought necessary to promote high cell proliferation,tumor progression and metastasis.This makes iron metabolism an attractive therapeutic target.Unfortunately,current iron-based therapeutic strategies often lack effectiveness and can elicit off-target toxicities.We report here a dual-therapeutic prodrug,DOXjade,that allows for iron chelation chemo-photothermal cancer therapy.This prodrug takes advantage of the clinically approved iron chelator deferasirox(ExJade®)and the topoisomerase 2 inhibitor,doxorubicin(DOX).Loading DOXjade onto ultrathin 2D Ti_(3)C_(2) MXene nanosheets produces a construct,Ti_(3)C_(2)-PVP@DOXjade,that allows the iron chelation and chemotherapeutic functions of DOXjade to be photo-activated at the tumor sites,while potentiating a robust photothermal effect with photothermal conversion efficiencies of up to 40%.Antitumor mechanistic investigations reveal that upon activation,Ti_(3)C_(2)-PVP@DOXjade serves to promote apoptotic cell death and downregulate the iron depletion-induced iron transferrin receptor(TfR).A tumor pH-responsive iron chelation/photothermal/chemotherapy antitumor effect was achieved both in vitro and in vivo.The results of this study highlight what may constitute a promising iron chelation-based phototherapeutic approach to cancer therapy. | Yunjie Xu Yingwei Wang Jusung An Adam C.Sedgwick Mingle Li Jianlei Xie Weibin Hu Jianlong Kang Sajal Sen Axel Steinbrueck Bin Zhang Lijun Qiao Swelm Wageh Jonathan F.Arambula Liping Liu Han Zhang Jonathan L.Sessler Jong Seung Kim | 2022 | Bioactive Materials2022，7，8： | 2 |
| 14 | Distribution and sources of polycyclic aromatic hydrocarbons from urban to rural soils: A case study in Dalian, China显示文摘 | Zhen Wang Jingwen Chen Xianliang Qiao Ping Yang Fulin Tian Liping Huang | 2007 | Chemosphere2007，，5： | 2 |
| 15 | Potential particulate pollution derived from UV-induced degradation of odorous dimethyl sulfide显示文摘UV-induced degradation of odorous dimethyl sulfide(DMS) was carried out in a static White cell chamber with UV irradiation.The combination of in situ Fourier transform infrared(FT-IR) spectrometer,gas chromatograph-mass spectrometer(GC-MS),wide-range particle spectrometer(WPS) technique,filter sampling and ion chromatographic(IC) analysis was used to monitor the gaseous and potential particulate products.During 240 min of UV irradiation,the degradation efficiency of DMS attained 20.9%,and partially oxidized sulfur-containing gaseous products,such as sulfur dioxide(SO2),carbonyl sulfide(OCS),dimethyl sulfoxide(DMSO),dimethyl sulfone(DMSO2) and dimethyl disulfide(DMDS) were identified by in situ FT-IR and GC-MS analysis,respectively.Accompanying with the oxidation of DMS,suspended particles were directly detected to be formed by WPS techniques.These particles were measured mainly in the size range of accumulation mode,and increased their count median diameter throughout the whole removal process.IC analysis of the filter samples revealed that methanesulfonic acid(MSA),sulfuric acid(H2SO4) and other unidentified chemicals accounted for the major non-refractory compositions of these particles.Based on products analysis and possible intermediates formed,the degradation pathways of DMS were proposed as the combination of the O(1D)-and the OH-initiated oxidation mechanisms.A plausible formation mechanism of the suspended particles was also analyzed.It is concluded that UV-induced degradation of odorous DMS is potentially a source of particulate pollutants in the atmosphere. | Liping Qiao Jianmin Chen Xin Yang | 2011 | Journal of Environmental Sciences2011，23，1： | 2 |
| 16 | Comparative performance of hybrid generations reveals the potential application of F_(2)hybrids in upland cotton显示文摘Background:The utilization of heterosis has greatly improved the productivity of cotton worldwide.However,a major constraint for the large-scale promotion of F_(1) hybrid cotton is artificial emasculation and pollination.This study proposed the potential utilization of F_(2) hybrids to improve upland cotton production through a comparative evaluation of hybrid generations.Results:Eight upland cotton varieties were analyzed and crosses were made according to NCII incomplete diallel cross-breeding design in two cotton belts of China.Variance analysis revealed significant differences in agronomic,yield,and fiber quality in both generations and environments.The broad-sense heritability of agronomic and yield traits was relatively higher than quality traits.Furthermore,the narrow-sense heritability of some traits was higher in F_(2) than in the F_(1) generation in both cotton belts.Overall,parental lines Zhong901,ZB,L28,and Z98 were observed with maximum combining ability while combinations with strong special combining ability were ZB×DT,L28×Z98,and ZB×851.The yield traits heterosis was predominant in both generations.However,the level of heterosis was altered with trait,hybrid combination,generation,and environment.Interestingly,L28×Z98 performed outstandingly in Anyang.Its lint yield(LY)was 24.2%higher in F_(1) and 11.6%in F_(2) than that of the control Ruiza 816.The performance of SJ48×Z98 was excellent in Aral which showed 36.5%higher LY in F_(2)and 10.9%in F_(2)than control CCRI 49.Further results revealed most hybrid combinations had shown a low level of heterosis for agronomic and fiber quality traits in both generations.Comparatively,ZB×DT and L28×Z98 showed hybrid vigor for multiple traits in both generations and cotton belts.It is feasible to screen strong heterosis hybrid combinations with fine fiber in early generations.In the two environments,the correlation of some traits showed the same trend,and the correlation degree of Anyang site was higher than that of Aral site,and the correlation of some traits showed the opposite trend.According to the performance of strong heterosis hybrid combinations in different environments,the plant type,yield and fiber traits associated with them can be improved according to the correlation.Conclusions:Through comparative analysis of variance,combining ability,and heterosis in F_(2)and F_(2)hybrids in different cotton belts,this study proposed the potential utilization of F_(2)hybrids to improve upland cotton productivity in China. | CHEN Liangliang TANG Huini ZHANG Xuexian QI Tingxiang GUO Liping SHAHZAD Kashif WANG Hailin QIAO Xiuqin ZANG Rong ZHANG Meng WU Jianyong XING Chaozhu | 2022 | Journal of Cotton Research2022，5，2： | 2 |
| 17 | A model for the transportation and distribution of jellyfish Rhopilema esculentum for stock enhancement in the Liaodong Bay, China显示文摘A numerical model for jellyfish Rhopilema esculentum stock enhancement is developed for the first time. The model is based on an operational ocean circulation-surface wave coupled forecasting system for the seas off China and adjacent areas and uses a Lagrangian particle-tracking scheme to track the trajectories of released jellyfish. The Jellyfish are modeled as particles with diel vertical migration and are passively drifted by the current and dispersion due to the sub-grid processes. A comparison between the simulation and survey results demonstrate that the model can capture the primary distribution patterns of the released jellyfish. The model results show that the ocean current and indirect wind impact are the main drivers controlling the jellyfish transport. A connectivity matrix between the release sites and fishing grounds indicates the top of the bay is better than the eastern and western coasts for jellyfish fishing. The matrix also shows that only 45% and 27% of the jellyfish released from Wafangdian(WFD) can enter the fishing ground in 2008 and 2010; thus, the site near WFD is not an advisable location for jellyfish release. A Lagrangian probability density function based on a nine-year tracing experiment validates the results and further provides a 'climatology' distribution of the released jellyfish.Several experiments are conducted to examine the sensitivity of the model to random walk schemes and to release conditions. The model requires a random walk but is insensitive to the random walk scheme. The experiments with different habitat depths show that if the jellyfish are fixed on the bottom of the water, most of them will be transported to the center, or even out of the bay, by the bottom circulation. | Liping Yin Xiujuan Shan Chang Zhao Xianshi Jin Guansuo Wang Fangli Qiao | 2019 | Acta Oceanologica Sinica2019，38，1： | 2 |
| 18 | Photocatalytic degradation of Orange G on nitrogen-doped TiO 2 catalysts under visible light and sunlight irradiation显示文摘 | Jianhui Sun Liping Qiao Shengpeng Sun Guoliang Wang | 2007 | Journal of Hazardous Materials2007，，1： | 1 |
| 19 | Expression of EphA2 receptor in ovarian cancer tissue 显示文摘 | HAN LIPING DONG ZIMING QIAO YUHUAN | 2005 | Journal of Zhengzhou University(Medical Sciences )2005，40，2： | 1 |
| 20 | An analytical model for complete dynamical coefficients of a tilting-pad journal bearing 显示文摘 | YAN Zhiyong WANG Liping QIAO Guang | 2010 | Tribology International2010，43，1： | 1 |
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