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| 1 | Epidemiological Characteristics of Plague in the Meriones unguiculatus Plague Focus--Inner Mongolia Autonomous Region,China,1950−2019显示文摘From 1950 to 2019,a total of 267 plague cases in humans were reported in the Inner Mongolia Autonomous Region with 133 deaths and 10,710 Yersinia pestis isolates;21 of these cases were reported from the Meriones unguiculatus(M.unguiculatus)plague focus with 6 deaths and 6,771 isolates.According to the plague situation in the Inner Mongolia Autonomous Region and the implementation of local preventive measures,the prevalence of plague in humans in the M.unguiculatus plague focus of the Inner Mongolia Autonomous Region could be divided into four stages.The first stage was the initial stage of plague prevention and control(1950–1959),with 0.80 cases annually and a case fatality rate of 37.50%.The second stage was the plague eradication stage(1960–1979),with 0.15 cases annually and a case fatality rate of 33.33%.The third stage was the plague surveillance stage(1980-1999),with 0.25 cases annually and a case fatality rate of 20.00%.The fourth stage is the comprehensive prevention and control stage under the emergency system(2000-2019),with 0.25 cases annually and a case fatality rate of 20.00%.The surveillance of rodent density(1981-2019)and studies on plague-related factors among M.unguiculatus have shown that the higher the M.unguiculatus density,the higher the nocturnal rodent capture rate(r=0.670,p<0.05)and the higher the indirect hemagglutination assay(IHA)positive rate of M.unguiculatus(r=0.344,p<0.05);the higher the percentage of hosts infected,the lower the M.unguiculatus density(r=-0.361,p<0.05)and the lower the IHA positive rate of M.unguiculatus(r=-0.337,p<0.05);the higher the percentage of nests infected with fleas,the lower the IHA positive rate of M.unguiculatus(r=-0.348,p<0.05).Together,these results suggest that it is necessary to simultaneously monitor the pathogens,serology,and vector index of M.unguiculatus to accurately reflect the plague prevalence among local animals.Although bubonic plague is the main plague type of the M.unguiculatus plague focus,severe pneumonic plague or septic plague may be secondary when the bubonic plague is misdiagnosed or not treated in time.In addition,the plague in animals is relatively virulent in the M.unguiculatus plague focus,and the risk of spreading to humans is higher.For plague in the Inner Mongolia Autonomous Region,comprehensive control efforts should be aimed at the M.unguiculatus focus,covering host animals,vector insects,and humans. | Boxi Liu Dayu Zhang Yuhuang Chen Zhaokai He Jun Liu Dongyue Lyu Weiwei Wu Ran Duan Shuai Qin Junrong Liang Huaiqi Jing Xin Wang | 2020 | China CDC weekly2020，2，49： | 3 |
| 2 | Toxicity assessment and long-term three-photon fluorescence imaging of bright aggregation-induced emission nanodots in zebrafish显示文摘导致聚集的排放(AIE ) luminogen 显示明亮的荧光并且处于它的聚集状态有 photobleaching 电阻。它是理想荧光灯为 bioimaging 的对比代理人。自从深渗透进生物纸巾拥有能力, Multiphoton 显微镜学是为 bioimaging 的一个重要工具。此处,我们为 zebrafish 的长期的成像和 multiphoton 显微镜学使用了 AIE luminogen。典型 AIE luminogen ,2,3二度(4-(苯基(4-( 1,2,2-triphenylvinyl )苯基)氨基)苯基) fumaronitrile ( TPE-TPA-FN 或 TTF ),与1,2-distearoyl-sn-glycero-3-phosphoethanola-mine-N-被包含[ methoxy (聚乙烯乙二醇)-2000]( DSPE-mPEG2000 )到在 1,560 nm-femtosecond ( fs )下面展出了明亮三光子的荧光的形式 nanodots 激光刺激。TTF-nanodots 在大量 pH 价值是化学上稳定的并且根据一系列生物测试在 zebrafish 在 vivo 毒性不出现了。TTF-nanodots 是进 zebrafish 胚胎的 microinjected,并且标记的胚胎的不同生长阶段与一台三光子的荧光显微镜被监视。TTF-nanodots 能在 zebrafish 身体内被跟踪为只要 120 个小时。另外, TTF-nanodots 被利用指向 zebrafish 的血容器,并且三光子的荧光 angiogram 被执行。更重要地,这些 nanodots 对在 1,560 nm-fs 刺激下面的 photobleaching 高度抵抗,允许 zebrafish 的长期的成像。 | Dongyu Li Xinyuan Zhao Wei Qin Hequn Zhang Yue Fei Liwei Liu Ken-Tye Yong Guangdi Chen Ben Zhong Tang Jun Qian | 2016 | Nano Research2016，9，7： | 2 |
| 3 | Clinical Observation of Huatanjieyu Granule in the Treatment of Post-stroke Depression显示文摘[Objectives]To observe the clinical effect of Huatanjieyu granule on patients with post-stroke depression.[Methods]Total 76 patients with confirmed post-stroke depression were randomly divided into two groups(treatment group and control group)according to the double-blind principle.The treatment group(38 cases)was treated with Huatanjieyu granule combined with escitalopram,and the control group(38 cases)was treated with escitalopram alone.The course of treatment was 6 weeks.Through clinical efficacy,Hamilton Depression Scale(HAMD)and Treatment Emergent Symptom Scale(TESS)scores were compared,and blood,liver function,renal function and electrocardiogram were examined.[Results]The scores of HAMD and TESS in patients with post-stroke depression were significantly decreased by Huatanjieyu granule,and there were no obvious side effects.The total effective rate was 92.1%in the treatment group and 76.3%in the control group.There was significant difference between the two groups(P<0.01).[Conclusions]Huatanjieyu granule was effective in the treatment of post-stroke depression with little side effects and was easy to be accepted by patients. | Xi WANG Chunqi AI Lizhu LIU Dongyu XIA Qin GONG | 2020 | Medicinal Plant2020，11，3： | 2 |
| 4 | Recent developments in regenerative ophthalmology显示文摘Regenerative medicine(RM)is one of the most promising disciplines for advancements in modern medicine,and regenerative ophthalmology(RO)is one of the most active fields of regenerative medicine.This review aims to provide an overview of regenerative ophthalmology,including the range of tools and materials being used,and to describe its application in ophthalmologic subspecialties,with the exception of surgical implantation of artificial tissues or organs(e.g.,contact lens,artificial cornea,intraocular lens,artificial retina,and bionic eyes)due to space limitations.In addition,current challenges and limitations of regenerative ophthalmology are discussed and future directions are highlighted. | Ye Shen He Shen Dongyu Guo Xinghuai Sun Yuan Sun Nan Hong Xiawei Wang Chen Xie Yuan Zhao Qin He Le Jin Yingying Wen Bo Jiang Chenying Yu Miaomiao Zhu Feng Cai Jianwu Dai | 2020 | Science China(Life Sciences)2020，63，10： | 2 |
| 5 | An im- proved hybrid technique for computing the RCS of dihedral comer reflector with a protmsion显示文摘 | Xia Dongyu Qin Kaibing Pan Yingfeng | 2009 | IEEE Microwave Antenna Propagation and EMC Technol- ogies for Wireless Communications2009，，： | 1 |
| 6 | Transformation of pollutants in landfill leachate treated by a combined sequence batch reactor, coagulation, Fenton oxidation and biological aerated filter technology显示文摘 | Yanyu Wu Shaoqi Zhou Xiuya Ye Dongyu Chen Ke Zheng Fanghui Qin | 2010 | Process Safety and Environmental Protection2010，，2： | 1 |
| 7 | Relationship Between Climate Change and Marmot Plague of Marmota himalayana Plague Focus—the Altun Mountains of the Qinghai-Xizang Plateau,China,2000–2022显示文摘Introduction:Plague is a zoonotic disease that occurs naturally in specific geographic areas.Climate change can influence the populations of the plague host or vector,leading to variations in the occurrence and epidemiology of plague in animals.Methods:In this study,we collected meteorological and plague epidemiological data from the Marmota himalayana plague focus in the Altun Mountains of the Qinghai-Xizang Plateau.The data spanned from 2000 to 2022.We describe the climatic factors and plague epidemic conditions and we describe their analysis by Pearson’s correlation.Results:During the period from 2000 to 2022,the isolation rates of Yersinia pestis(Y.pestis)from marmots and fleas were 9.27%(451/4,864)and 7.17%(118/1,646),respectively.Additionally,we observed a positive rate of F1 antibody of 11.25%(443/3,937)in marmots and 18.16%(142/782)in dogs.With regards to climate,there was little variation,and a decreasing trend in blowing-sand days was observed.The temperature in the previous year showed a negative correlation with the Y.pestis isolation rate in marmots(r=−0.555,P=0.011)and the positive rate of F1 antibody in marmots(r=−0.552,P=0.012)in the current year.The average annual precipitation in the previous two years showed a positive correlation with marmot density(r=0.514,P=0.024),while blowingsand days showed a negative correlation with marmot density(r=−0.701,P=0.001).Furthermore,the average annual precipitation in the previous three years showed a positive correlation with the isolation rate of Y.pestis from marmots(r=0.666,P=0.003),and blowing-sand days showed a negative correlation with marmot density(r=−0.597,P=0.009).Conclusions:The findings of this study indicate that there is a hysteresis effect of climate change on the prevalence of plague.Therefore,monitoring climate conditions can offer significant insights for implementing timely preventive and control measures to combat plague epidemics. | Qun Duan Xiaojin Zheng Zhiqiang Gan Dongyue Lyu Hanyu Sha Xinmin Lu Xiaoling Zhao Asaiti Bukai Ran Duan Shuai Qin Li Wang Jinxiao Xi Di Wu Peng Zhang Deming Tang Zhaokai He Huaiqi Jing Biao Kan Xin Wang | 2024 | China CDC weekly2024，6，4： | 0 |
| 8 | Identification of Novel Bartonella washoensis Sequence Type 22 in Marmota himalayana-Jiuquan City,Gansu Province,China,2021–2022显示文摘Summary What is already known about this topic?The prevalence of rodent-adapted Bartonella species has been increasing significantly.However,the specific Bartonella species carried by Marmota himalayana(M.himalayana),a large rodent species,and the potential risk it poses to human populations remain unknown.What is added by this report?Bartonella washoensis(B.washoensis),associated with human endocarditis,was initially identified in M.himalayana,exhibiting a detection rate of approximately one-third and demonstrating a predilection for the heart and lungs.The discovery of the novel Sequence Type 22 has expanded both the isolation source and genetic lineage of B.washoensis.What are the implications for public health practice?Individuals residing within the M.himalayana plague focus are at an elevated risk for B.washoensis infection.Consequently,there is a pressing need for public health warnings and efficient clinical case identification in this population. | Ran Duan Xiaojin Zheng Qun Duan Asaiti Bukai Peng Zhang Shuai Qin Xinmin Lu Dongyue Lyu Haonan Han Dan Zhang Zhaokai He Junrong Liang Deming Tang Jinxiao Xi Huaiqi Jing Xin Wang | 2023 | China CDC weekly2023，5，20： | 0 |
| 9 | Improvement of Poplar Bark Extract on Physiological Characters of Lactococcus lactis in Intestine of White Feather Broilers显示文摘[Objective]The paper was to study the improvement of poplar bark extract on intestinal Lactococcus lactis of white feather broilers.[Method]Totally 450 Ross 308 white-feather broilers were randomly divided into five groups:control group,low dose group,medium dose group,high dose group,and antibiotic group(oxytetracycline hydrochloride).The feeding duration was 45 d.The probiotics were screened and isolated through homology,and the physiological and biochemical characteristics of chicken intestinal bacteria in different groups were compared to determine the properties of bacterial strain.The drug resistance,antibacterial ability,proliferation ability,acid resistance and bile salt resistance of isolated strain were tested,and a strain of L.lactis was obtained.[Result]The isolated L.lactis was sensitive to other drugs except natural tetracyclines,and there was no significant difference among the four groups except oxytetracycline group;as the concentration of extract increased,the inhibition of L.lactis against Salmonella sp.increased;the medium dose extract had the largest increase in the ability to tolerate the proliferation of L.lactis.[Conclusion]Feeding poplar bark extract will produce positive effects on the physiological characters of intestinal L.lactis in broiler chicken,which will provide potential probiotic strain for chicken production. | Liu Guofang Zheng Guangyao He Pengfei Song Chunlei Yan Linlin Chen Ming Luo Guilan Liu Fu'an Zhu Haoyuan Qin Dongyu | 2020 | Animal Husbandry and Feed Science2020，12，3： | 0 |
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