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| 1 | A 4-bp Insertion at ZmPLA 1 Encoding a Putative Phospholipase A Generates Haploid Induction in Maize显示文摘 | Chenxu Liu Xiang Li Dexuan Meng Yu Zhong Chen Chen Xin Dong Xiaowei Xu Baojian Chen Wei Li Liang Li Xiaolong Tian Haiming Zhao Weibin Song Haishan Luo Qinghua Zhang Jinsheng Lai Weiwei Jin Jianbing Yan Shaojiang Chen | 2017 | Molecular Plant2017，10，3： | 39 |
| 2 | Laboratory culture of the freshwater benthic gastropod Bellamya aeruginosa (Reeve) and its utility as a test species for sediment toxicity显示文摘This study aimed to develop original laboratory culture and sediment toxicity testing protocols for the freshwater gastropod Bellamya aeruginosa(Reeve),a new potential species for sediment toxicity testing.B.aeruginosa was successfully cultured with an effective culture system under proposed laboratory conditions.Optimal ad libitum feeding levels for larvae,juveniles,and adults were 2.0,6.0,and 16.0 mg fish food/(snail·day),respectively.Mean survival rates of juveniles were higher than 90%.The snails could be sexed at 9 weeks of age,and their generation time is approximately 4 months.Reproduction continued all year around;the mean fecundity was 0.55 newborn/(female·day).The utility of this species for bioassays was evaluated in both 10-day and 28-day case studies with artificial sediments.The 10-day LC50 of Cu for larvae was 480 μg/g dry weight(dw),and the lowest observed effects concentration of Cu for survival and growth of larvae was 195 μg/g dw.Survival and growth are reliable indicators of acute toxicity.Larvae accumulated more Cu than adults.B.aeruginosa exhibited a higher sensitivity to Cu exposure than standard test species(Hyalella azteca and Chironomus tentans).The 28-day test of sediment toxicity with adults showed that fecundity was a robust endpoint indicator of reproductive toxicity,and the biochemical endpoints of superoxide dismutase,catalase,and glutathione could be used as sensitive biomarkers for Cu-induced oxidative damage.B.aeruginosa can be therefore recommended as a candidate for the standardization of the freshwater sediment toxicity test protocol. | Taowu Ma Shuangjiao Gong Ke Zhou Cheng Zhu Kaidong Deng Qinghua Luo Zijian Wang | 2010 | Journal of Environmental Sciences2010，22，2： | 22 |
| 3 | MicroRNAs Involved in Skeletal Muscle Differentiation显示文摘MicroRNAs (miRNAs) negatively regulate gene expression by promoting degradation of target mRNAs or inhibiting their translation. Previous studies have expanded our understanding that miRNAs play an important role in myogenesis and have a big impact on muscle mass, muscle fiber type and muscle-related diseases. The muscle-specific miRNAs, miR-206, miR-1 and miR-133, are among the most studied and best characterized miRNAs in skeletal muscle differentiation. They have a profound influence on multiple muscle differ-entiation processes, such as alternative splicing, DNA synthesis, and cell apoptosis. Many non-muscle-specific miRNAs are also required for the differentiation of muscle through interaction with myogenic factors. Studying the regulatory mechanisms of these miRNAs in muscle differentiation will extend our knowledge of miRNAs in muscle biology and will improve our understanding of the myogenesis regulation. | Wen Luo Qinghua Nie Xiquan Zhang | 2013 | Journal of Genetics and Genomics2013，40，3： | 19 |
| 4 | Discrimination of abiogenic and biogenic alkane gases显示文摘We have combined the analytical data of the carbon isotope distribution pattern, R/Ra and CH4/3He values of abiogenic and biogenic (referring to the thermogenic and bacterial or microbial) alkane gases in China with those of alkane gases from USA, Russia, Germany, Australia and other countries. Four discrimination criteria are derived from this comparative study: 1) Carbon isotopic composition is generally greater than -30‰ for abiogenic methane and less than -30‰ for biogenic methane; 2) Abiogenic alkane gases have a carbon isotopic reversal trend (δ 13C1> δ 13C2> δ 13C3> δ 13C4) with δ 13C1>-30‰ in general; 3) Gases with R/Ra >0.5 and δ 13C11 δ 13C2>0 are of abiogenic origin; 4) Gases (meth- ane) with CH4/3He≤106 are of abiogenic origin, whereas gases with CH4/3He≥1011 are of biogenic origin. | DAI JinXing ZOU CaiNeng ZHANG ShuiChang LI Jian NI YunYan HU GuoYi LUO Xia TAO ShiZhen ZHU GuangYou MI JingKui LI ZhiSheng HU AnPing YANG Chun ZHOU QingHua SHUAI YanHua ZHANG Ying MA ChengHua | 2008 | Science China Earth Sciences2008，51，12： | 17 |
| 5 | Distant eQTLs and Non-coding Sequences Play Critical Roles in Regulating Gene Expression and Quantitative Trait Variation in Maize显示文摘 | Haijun Liu Xin Luo Luyao Niu Yingjie Xiao Lu Chen Jie Liu Xiaqing Wang Minliang Jin Wenqiang Li Qinghua Zhang Jianbing Yan | 2017 | Molecular Plant2017，10，3： | 13 |
| 6 | Feed conversion ratio,residual feed intake and cholecystokinin type A receptor gene polymorphisms are associated with feed intake and average daily gain in a Chinese local chicken population显示文摘Background: The feed conversion ratio(FCR) and residual feed intake(RFI) are common indexes in measuring feed efficiency for livestock. RFI is a feed intake adjusted for requirements for maintenance and production so these two traits are related. Similarly, FCR is related to feed intake and weight gain because it is their ratio. Cholecystokinin type A receptor(CCKAR) plays an important role in animal digestive process. We examined the interplay of these three parameters in a local Chinese chicken population.Results: The feed intake(FI) and body weights(BW) of 1,841 individuals were monitored on a daily basis from 56 to 105 d of age. There was a strong correlation between RFI and average daily feed intake(ADFI) and a negative correlation between the FCR and daily gain(r_g=-0.710). Furthermore, we identified 51 single nucleotide polymorphisms(SNPs) in the CCKAR and 4 of these resulted in amino acid mutations. The C334A mutation was specifically associated with FI and the expected feed intake(EFI)(P < 0.01) and significantly associated with the average daily gain(ADG)(P < 0.05). G1290A was significantly associated with FI and EFI(P < 0.05).Conclusion: FCR is apply to weight selecting, and RFI is more appropriate if the breeding focus is feed intake. And C334A and G1290A of the CCKAR gene can be deemed as candidate markers for feed intake and weight gain. | Zhenhua Yi Xing Li Wen Luo Zhenqiang Xu Congliang Ji Yan Zhang Qinghua Nie Dexiang Zhang Xiquan Zhang | 2018 | Journal of Animal Science and Biotechnology2018，9，4： | 7 |
| 7 | Regulatory mechanism of hormones of the pituitary-target gland axes in kidney-Yang deficiency based on a support vector machine model显示文摘OBJECTIVE:To study the development mechanism of kidney-Yang deficiency through the establishment of support vector machine models of relevant hormones of the pituitary-target gland axes in rats with kidney-Yang deficiency syndrome.METHODS:The kidney-Yang deficiency rat model was created by intramuscular injection of hydrocortisone,and contents of the hormones of the pituita- ry-thyroid axis:thyroid stimulating hormone(TSH),3,3',5-triiodothyronine(T_3) and thyroxine(T_4);hormones of the pituitary-adrenal gland axis:adrenocorticotropic hormone(ACTH) and Cortisol(CORT);and hormones of the pituitary-gonadal axis:luteinizing hormone(LH),follicle-stimulating hormone(FSH),and testosterone(T),were determined in the early,middle,and advanced stages.Ten support vector regression(SVR) models of the hormones were established to analyze the mutual relationships among the hormones of the three axes.RESULTS:The feedback control action of the pituitary-adrenal axis began to lose efficacy from the middle stage of kidney-Kong deficiency.The contents all hormones of the three pituitary-target gland axes decreased in the advanced stage.Relative errors of the jackknife test of the SVR models all were less than 10%.CONCLUSION:Imbalances in mutual regulation among the hormones of the pituitary-target gland axes,especially loss of effectiveness of the pituitary-adrenal axis,is one pathogenesis of kidney-Yang deficiency.The SVR model can accurately reflect the complicated non-linear relationships among pituitary-target gland axes in rats with of kidney-Yang deficiency. | Wang Xiufeng Zhang Lei Huang Rongbo Wu Qinghua Min Jianxin Ma Na Luo Laicheng | 2015 | Journal of Traditional Chinese Medicine2015，35，2： | 7 |
| 8 | Why are oseltamivir and zanamivir effective against the newly emerged influenza A virus (A/HIN1)?显示文摘 | Kunqian Yu Cheng Luo Guangrong Qin Zhijian Xu Ning Li Hong Liu Xu Shen Jianpeng Ma Qinghua Wang Caiguang Yang Weiliang Zhu Hualiang Jiang | 2009 | Cell Research2009，19，10： | 6 |
| 9 | A hybrid carboxylate-water decamer with a discrete octameric water moiety self-assembled in a 2D copper(Ⅱ) coordination polymer显示文摘An octameric water moiety which consists of a chairlike water hexamer and two pendent water molecules in the 1,4-diaxial positions and shows a similar structure to the hydrocarbon(1r,4r)-1,4-dimethylcyclohexane,is unambiguously trapped in a2D Cu(Ⅱ) mixed-ligand coordination polymer,{[Cu2(bpp)2(H2O)2(bpda)2 ].6H2O} n(1)(bpp = 1,3-bis(4-pyridyl)propane and H2 bpda =2,2'-biphenyldicarboxylic acid).The water octamer can be extended into a hybrid carboxylate-water decamer when carboxylic oxygen atoms from bpda2 are involved.Interestingly,the present hybrid decamer bears a similar structural topology to a butterfly(H2O) 10 cluster.The reversible dehydration/hydration of 1 is determined by X-ray powder diffraction studies. | LUO GengGeng WU DongLiang LIU Li LI DongXu ZHAO QingHua XIAO ZiJing DAI JingCao | 2012 | Science China Chemistry2012，55，7： | 3 |
| 10 | Segmentation algorithm for Hangzhou white chrysanthemums based on least squares support vector machine显示文摘In order to realize the visual positioning for Hangzhou white chrysanthemums harvesting robot in natural environment,a color image segmentation method for Hangzhou white chrysanthemum based on least squares support vector machine(LS-SVM)was proposed.Firstly,bilateral filter was used to filter the RGB channels image respectively to eliminate noise.Then the pixel-level color feature and texture feature of the image,which was used as input of LS-SVM model(classifier)and SVM model(classifier),were extracted via RGB value of image and gray level co-occurrence matrix.Finally,the color image was segmented with the trained LS-SVM model(classifier)and SVM model(classifier)separately.The experimental results showed that the trained LS-SVM model and SVM model could effectively segment the images of the Hangzhou white chrysanthemums from complicated background taken under three illumination conditions such as front-lighting,back-lighting and overshadow,with the accuracy of above 90%.When segmenting an image,the SVM algorithm required 1.3 s,while the LS-SVM algorithm proposed in this paper just needed 0.7 s,which was better than the SVM algorithm obviously.The picking experiment was carried out and the results showed that the implementation of the proposed segmentation algorithm on the picking robot could achieve 81%picking success rate. | Qinghua Yang Shaoliang Luo Chun Chang Yi Xun Guanjun Bao | 2019 | International Journal of Agricultural and Biological Engineering2019，12，4： | 3 |
| 11 | A reactive oxygen species burst causes haploid induction in maize显示文摘Haploid induction (HI) is an important tool in crop breeding. Phospholipase A1 (ZmPLA1)/NOT LIKE DAD (NLD)/MATRILINEAL (MTL) is a key gene controlling HI in maize;however, the underlying molecular mechanism remains unclear. In this study, to dissect why loss of ZmPLA1 function could mediate HI we performed a comprehensive multiple omics analysis of zmpla1 mutant anthers by integrating transcriptome, metabolome, quantitative proteome, and protein modification data. Functional classes of significantly enriched or differentially abundant molecular entities were found to be associated with the oxidative stress response, suggesting that a reactive oxygen species (ROS) burst plays a critical role in HI. In support of this, we further discovered that a simple chemical treatment of pollen with ROS reagents could lead to HI. Moreover, we identified ZmPOD65, which encodes a sperm-specific peroxidase, as a new gene controlling HI. Taken together, our study revealed a likely mechanism of HI, discovered a new gene controlling HI, and created a new method for HI in maize, indicating the importance of ROS balance in maintaining normal reproduction and providing a potential route to accelerate crop breeding. | Chenglin Jiang Ju Sun Rui Li Shijuan Yan Wei Chen Liang Guo Guochen Qin Pengcheng Wang Cheng Luo Wenjie Huang Qinghua Zhang Alisdair R.Fernie David Jackson Xiang Li Jianbing Yan | 2022 | Molecular Plant2022，15，6： | 2 |
| 12 | The effect of SiO_2 particle size on iron based F–T synthesis catalysts显示文摘The effect of particle size of silica, as catalyst binder, on the chemical and mechanical properties of iron based FT catalyst was studied in this work. The samples were characterized using XRD, BET, TEM, FT-IR, and H2-TPR, respectively. The attrition resistance and the FT activity were tested. Si-8–Si-15 catalysts prepared with 8–15 nm silica sol show good attrition resistance(attrition loss b 4%), especially Si-13 with an attrition loss of 1.89%. Hematite appeared in XRD patterns when silica sol above 15 nm is used. TEM micrographs show that no obvious Si O_2 particles appear when silica sol particle with size less than 8 nm was used, but Si O_2 particles coated with small ferrihydrite particles appear when silica sol above 8 nm was used. Si–O–Si vibration peak in FT-IR spectra increases with increasing silica sol size. Samples prepared with silica sol show good stability of FT reactions, and the average molecular weight of FT products increases with the increase of Si O_2 particle. | Xiuying Guo Yijun Lu Peng Wu Kui Zhang Qinghua Liu Mingsheng Luo | 2016 | Chinese Journal of Chemical Engineering2016，24，7： | 2 |
| 13 | Thallium contamination in agricultural soils and associated potential remediation via biochar utilization显示文摘Thallium(Tl)is an extremely harmful metal that is substantially distributed in the environment.It can threaten human health via consumption of food potentially derived from Tl-contaminated agricultural production.Little information is available on how to utilize biochar to remediate Tl contamination in agricultural soils.More efforts are urgently needed to be devoted to developing effective techniques to empower biochar with high selectivity of Tl in agricultural soils.In this review,we provided comprehensive information on Tl contamination in agricultural soils.We also discussed recent developments and assessed the current status of biochar applications.We briefly reviewed the bridge between biochar preparation technology and utilization wherein further developments can exhibit potential in terms of Tl remediation.Hence,biochar is expected to exhibit excellent Tl remediation performance in contaminated agricultural soils with promising application prospects.The obtained knowledge provides further insights into the remediation of Tl contamination in agricultural soils. | Zhuanxi Luo Alexis Kayiranga Ernest Uwiringiyimana Qinghua Zhang Changzhou Yan Jianhua Guo Baoshan Xing | 2020 | Biochar2020，2，1： | 2 |
| 14 | Current management of chemotherapy-induced neutropenia in adults:key points and new challenges显示文摘Chemotherapy-induced neutropenia(CIN)is a potentially fatal and common complication in myelosuppressive chemotherapy.The timing and grade of CIN may play prognostic and predictive roles in cancer therapy.CIN is associated with older age,poor functional and nutritional status,the presence of significant comorbidities,the type of cancer,previous chemotherapy cycles,the stage of the disease,specific chemotherapy regimens,and combined therapies.There are many key points and new challenges in the management of CIN in adults including:(1)Genetic risk factors to evaluate the patient’s risk for CIN remain unclear.However,these risk factors urgently need to be identified.(2)Febrile neutropenia(FN)remains one of the most common reasons for oncological emergency.No consensus nomogram for FN risk assessment has been established.(3)Different assessment tools[e.g.,Multinational Association for Supportive Care in Cancer(MASCC),the Clinical Index of Stable Febrile Neutropenia(CISNE)score model,and other tools]have been suggested to help stratify the risk of complications in patients with FN.However,current tools have limitations.The CISNE score model is useful to support decision-making,especially for patients with stable FN.(4)There are still some challenges,including the benefits of granulocyte colony stimulating factor treatment and the optimal antibiotic regimen in emergency management of FN.In view of the current reports,our group discusses the key points,new challenges,and management of CIN. | Committee of Neoplastic Supportive-Care(CONS),China Anti-Cancer Association Committee of Clinical Chemotherapy,China Anti-Cancer Association Yi Ba Yuankai Shi Wenqi Jiang Jifeng Feng Ying Cheng Li Xiao Qingyuan Zhang Wensheng Qiu Binghe Xu Ruihua Xu Bo Shen Zhiguo Luo Xiaodong Xie Jianhua Chang Mengzhao Wang Yufu Li Yuerong Shuang Zuoxing Niu Bo Liu Jun Zhang Li Zhang Herui Yao Conghua Xie Huiqiang Huang Wangjun Liao Gongyan Chen Xiaotian Zhang Hanxiang An Yanhong Deng Ping Gong Jianping Xiong Qinghua Yao Xin An Cheng Chen Yanxia Shi Jialei Wang Xiaohua Wang Zhiqiang Wang Puyuan Xing Sheng Yang Chenfei Zhou | 2020 | Cancer Biology & Medicine2020，17，4： | 2 |
| 15 | Yielding behavior of triplex medium Mn steel alternated with cooling strategies altering martensite/ferrite interfacial feature显示文摘In this paper, we report the influence of cooling processes on the yielding behavior of a medium Mn steel(MMS) with triplex microstructure, i.e. austenite(γ), ferrite(α) and as-quenched martensite(α’). After the intercritical annealing(IA) at both 725℃ and 750℃, the steel was subjected to the two cooling processes, i.e. air cooling(AC) and water quenching(WQ). It exhibits the discontinuous yielding after the AC following the IA at 750℃ while the continuous yielding after the WQ. Compared with WQ process,both the dilatometry and the microstructural examinations show that the AC process leads to lower Ms temperature, larger retained austenite(RA) fraction and less martensite, the latter is always companied with geometry necessary dislocations(GNDs) generated near the α/α’ interfaces. Considering the complexity of nanosized tri-phases in this steel, the presence of martensite with key features in the resultant specimens was systematically examined by atom probe tomography(APT) on the samples prepared by the specific target lift-out method. The APT results directly revealed the C/Mn co-segregation at the α’/αinterfaces in the AC samples but not in WQ samples. The numerical simulation results further suggest that the segregation of C and Mn at the α’/α interfaces may be due to different mechanisms. We conclude that the yielding of triplex MMS is determined by both the quantity of GNDs generated near theα/α’ interfaces, which increases with martensite fraction, and the extent of their immobilization resulting from the interfacial segregation of solute atoms when the presence of martensite is sufficient. WQ tends to suppress the discontinuous yielding of MMS since the rapid cooling may promote more martensite formed with the increasing quantity of GNDs and prevent the interfacial segregation of both C and Mn. | Bin Hu Xiao Shen Qinyi Guo Qinghua Wen Xin Tu Cancan Ding Fanglin Ding Wenwen Song Haiwen Luo | 2022 | Journal of Materials Science & Technology2022，，31： | 2 |
| 16 | Quantitative IR characterization of urea groups in waterborne polyurethanes显示文摘 | Shi Ying Zhan Xiaoli Luo Zhenhuan Zhang Qinghua Chen Fengqiu | 2008 | Journal of Polymer Science Part A:Polymer Chemistry2008，46，7： | 1 |
| 17 | Synthesis and oxidation behavior of boron-substituted carbon powders by hot filament chemical vapor deposition显示文摘Boron-substituted carbon powder, BxC1-x with x up to 0.17, has been successfully synthesized by hot filament chemical vapor deposition. The boron concentration in prepared BxC1-x samples can be controlled by varying the relative proportions of methane and diborane. X-ray diffraction, transmission electron microscopy, and electron energy loss spectrum confirm the successful synthesis of an amorphous BC5 compound, which consists of 10―20 nm particles with disk-like morphology. Thermogravimetry measurement shows that BC5 compound starts to oxidize ap-proximately at 620℃ and has a higher oxidation resistance than carbon. | HU QianKu WU QingHua SUN Guang LUO XiaoGuang XU Bo YU DongLi HE JuLong | 2008 | Science China(Technological Sciences)2008，51，9： | 1 |
| 18 | Conventional and RAFT Miniemulsion Copolymerizations of Butyl Methaerylate With Fluoromethacrylate and Monomer Reactivity Ratios显示文摘 | Qinghua Zhang Qiongyan Wang Zhenhuan Luo | 2009 | Polymer Engineering and Science2009，49，9： | 1 |
| 19 | Estrogen deficiency exacerbates learning and memory deficits associated with glucose metabolism disorder in APP/PS1 double transgenic female mice显示文摘Alterations in glucose metabolism occur in the brain in the early stage of Alzheimer's disease(AD),and menopausal women have more severe metabolic dysfunction and are more prone to dementia than men.Although estrogen deficiency-induced changes in glucose metabolism have been previously studied in animal models,their molecular mechanisms in AD remain elusive.To investigate this issue,double transgenic(APP/PS1)female mice were subjected to bilateral ovariectomy at 3 months of age and were sacrificed 1 week,1 month and 3 months after surgery to simulate early,middle and late postmenopause,respectively.Our analysis demonstrated that estrogen deficiency exacerbates learning and memory deficits in this mouse model of postmenopause.Estrogen deficiency impairs the function of mitochondria in glucose metabolism.It is possible that the occurrence of AD is associated with the aberrant mitochondrial ERβ-mediated IGF-1/IGF-1R/GSK-3βsignaling pathway.In this study,we established a potential mechanism for the increased risk of AD in postmenopausal women and proposed a therapeutic target for AD due to postmenopause. | Min Luo Qinghua Zeng Kai Jiang Yueyang Zhao Zhimin Long Yexiang Du Kejian Wang Guiqiong He | 2022 | Genes & Diseases2022，9，5： | 1 |
| 20 | Baeyer-Vil- liger oxidation of ketones with hydrogen peroxide eata-lyzed by Sn-palygorskite显示文摘 | Lei Ziqiang Zhang Qinghua Luo Jujie | 2005 | Tetrahedron Letters2005，46，20： | 1 |
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