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| 1 | Enhanced secondary pollution offset reduction of primary emissions during COVID-19 lockdown in China显示文摘To control the spread of the 2019 novel coronavirus(COVID-19),China imposed nationwide restrictions on the movement of its population(lockdown)after the Chinese New Year of 2020,leading to large reductions in economic activities and associated emissions.Despite such large decreases in primary pollution,there were nonetheless several periods of heavy haze pollution in eastern China,raising questions about the well-established relationship between human activities and air quality.Here,using comprehensive measurements and modeling,we show that the haze during the COVID lockdown was driven by enhancements of secondary pollution.In particular,large decreases in NOx emissions from transportation increased ozone and nighttime NO_(3)radical formation,and these increases in atmospheric oxidizing capacity in turn facilitated the formation of secondary particulate matter.Our results,afforded by the tragic natural experiment of the COVID-19 pandemic,indicate that haze mitigation depends upon a coordinated and balanced strategy for controlling multiple pollutants. | Xin Huang Aijun Ding Jian Gao Bo Zheng Derong Zhou Ximeng Qi Rong Tang Jiaping Wang Chuanhua Ren Wei Nie Xuguang Chi Zheng Xu Liangduo Chen Yuanyuan Li Fei Che Nini Pang Haikun Wang Dan Tong Wei Qin Wei Cheng Weijing Liu Qingyan Fu Baoxian Liu Fahe Chai Steven JDavis Qiang Zhang Kebin He | 2021 | National Science Review2021，8，2： | 47 |
| 2 | EMP chemical ages of monazites from Central Zone of the eastern Kunlun Orogen:Records of multi-tectonometamorphic events显示文摘Two generations of monazite were identified in one mica schist sample from the central zone of the eastern Kunlun Orogen at the northern margin of the Qinghai-Tibet Plateau. The first generation was found in the cores of garnet porphyroblasts with relatively high Y2O3 contents (averaging 1.012±0.088 wt%). The second generation occurs either as inclusions in the rims of garnet porphyroblasts,matrix kyanite,plagioclase and quartz,or as separate crystals associated with matrix biotite and muscovite mostly having a relatively low Y2O3 content (averaging 0.479±0.100 wt%). Electron microprobe (EMP) Th-U-Pbtotal chemical dating for two grains of the first generation monazite yields average ages of 455 ± 18 Ma and 420 ± 20 Ma,respectively; six grains of the second generation gave an average age of 246.1 ± 3.8 Ma. These ages suggest that the core and rim of the garnet porphyroblasts and their associated assemblages record two events of significant tectonometamorphism. The formation of the Ordovician monazite is related to the tectonometamorphic event responsible for continuous amalgamation of the Gondwanaland in the Late Pan-African period or for consumption of the Proto-Tethys,whereas the development of the Triassic monazite is related to the tectonometamorphic event for consumption of the Paleo-Tethys. | CHEN NengSong SUN Min WANG QingYan ZHAO GuoChun CHEN Qiang SHU GuiMing | 2007 | Chinese Science Bulletin2007，52，16： | 28 |
| 3 | Impact of meteorological conditions on a nine-day particulate matter pollution event observed in December 2013,Shanghai,China显示文摘A severe particulate matter pollution event occurred in Shanghai from 1 to 9 December 2013.The mean hourly mass concentrations of PM_(2.5) and PM_(10) were 211.9 and 249.0 μg/m^3,respectively.Reanalysis data,in situ,and remote-sensing measurements were used to examine the impacts of meteorological conditions on this event.It was found that the synoptic pattern of weak pressure,the reduced planetary boundary layer height,and the passage of two cold fronts were key factors causing the event.Four stages were identified during this event based on the evolution of its PM_(2.5) levels and weather conditions.The highest concentration of PM2.5(602 μg/m^3) was observed in stage 3.High PM2.5 concentrations were closely associated with a low local ventilation index,with an average of 505m^2/s,as well as with the influx of pollutants from upstream,transported by the cold fronts. | Jianming Xu Fengxia Yan Ying Xie Fengyun Wang Jianbin Wu Qingyan Fu | 2015 | Particuology2015，13，3： | 17 |
| 4 | De novo mutation in ATP6V1B2 impairs lysosome acidification and causes dominant deafness-onychodystrophy syndrome显示文摘 | Yongyi Yuan Jianguo Zhang Qing Chang Jin Zeng Feng Xin Jianjun Wang Qingyan Zhu Jing Wu Jingqiao Lu Weiwei Guo Xukun Yan Hui Jiang Binfei Zhou Qi Li Xue Gao Huijun Yuan Shiming Yang Dongyi Han Zixu Mao Ping Chen Xi Lin Pu Dai | 2014 | Cell Research2014，24，11： | 13 |
| 5 | Classification of hyperspectral remote sensing images using frequency spectrum similarity显示文摘An algorithm of hyperspectral remote sensing images classification is proposed based on the frequency spectrum of spectral signature.The spectral signature of each pixel in the hyperspectral image is taken as a discrete signal,and the frequency spectrum is obtained using discrete Fourier transform.The discrepancy of frequency spectrum between ground objects' spectral signatures is visible,thus the difference between frequency spectra of reference and target spectral signature is used to measure the spectral similarity.Canberra distance is introduced to increase the contribution from higher frequency components.Then,the number of harmonics involved in the proposed algorithm is determined after analyzing the frequency spectrum energy cumulative distribution function of ground object.In order to evaluate the performance of the proposed algorithm,two hyperspectral remote sensing images are adopted as experimental data.The proposed algorithm is compared with spectral angle mapper (SAM),spectral information divergence (SID) and Euclidean distance (ED) using the product accuracy,user accuracy,overall accuracy,average accuracy and Kappa coefficient.The results show that the proposed algorithm can be applied to hyperspectral image classification effectively. | WANG Ke GU XingFa YU Tao MENG QingYan ZHAO LiMin FENG Li | 2013 | Science China(Technological Sciences)2013，56，4： | 10 |
| 6 | Analysis and Calculation for Heating and Temperature Rise of Magnetic Levitation Device显示文摘准确的热分析是磁悬浮系统电磁装置优化设计、防止过热的前提。提出了基于等效热路模型的电磁装置发热及温升计算方法,并与基于"场"的仿真分析结果进行比较,验证其正确性。首先,利用ANSYS软件建立电磁装置的瞬态温度场模型,并将装置中动铁心随大轴旋转时与空气产生的风摩擦损耗包含在模型中,通过仿真分析,得到电磁装置温度分布;然后,通过对散热路径的分析建立了电磁装置的等效热路模型,从"路"的角度计算出本电磁装置各位置的温升;最后,将基于"路"的计算结果与基于"场"的仿真结果进行了比较分析,各部分温升误差均在允许范围内,验证了等效热路模型计算电磁装置发热及温升方法的准确性和可行性。在基于"场"和"路"的两种分析中,均考虑了电阻率随温升的变化,散热分析中均计及了导热系数和对流散热系数随温度的变化。 | MA Hongzhong GENG Zhihui WANG Qingyan ZHANG Zhiyan | 2012 | 中国电机工程学报2012，32，30： | 7 |
| 7 | Systematic Identification of the Light-quality Responding Anthocyanin Synthesis-related Transcripts in Petunia Petals显示文摘Previous studies have shown that high light intensity can induce anthocyanin synthesis(AS)in petunia plants.To identifywhich kind of light quality plays a role in inducing such metabolic process,and what transcripts participate in controlling it,we carried out whole-transcriptome sequencing and analysis of petunia petals treated with different light-quality conditions.Among the red and white light treatments,a total of 2205 differentially expressed genes and 15,22,and 20 differentially expressed circRNAs,miRNAs,and lncRNAs,were identified respectively.The AS-related genes,including the structural genes CHSj,F3H,F35H,DFR,and ANS,and the regulatory genes AN4,DPL,PHZ and MYBx were found to be downregulated under red light condition compared with their levels under white light condition.Furthermore,the light photoreceptor Cryptochrome 3(CRY3)and a series of light-dependent genes,such as PIF,HY5,andBBXs,were also determined to respond to the light treatments.The anthocyanin contents in early petunia petals under red light were significantly lower than that under white and blue light.The results of qRT-PCR further confirmed the expression pattern of some AS-related and light-response genes in response to different light quality.Yeast two-hybrid results showed that the key elements in the light signal pathway,HY5 can interact with BBX19,BBX24 and BBX25.And PHZ,the important AS regulator can induce anthocyanin synthesis in response to blue light quality fromtransient expression analysis in petunia petals.These findings presented here not only deepen our understanding of how light quality controls anthocyanin synthesis,but also allow us to explore potential target genes for improving pigment production in petunia flower petals. | Zhenzhu Fu Hongquan Shang Hui Jiang Jie Gao Xiaoyu Dong Huijuan Wang Yanmin Li Limin Wang Jing Zhang Qingyan Shu Yacong Chao Menglan Xu Rui Wang Liangsheng Wang Hechen Zhang | 2020 | Horticultural Plant Journal2020，6，6： | 7 |
| 8 | Analysis of interprovincial trade embodied carbon emissions in Beijing-Tianjin-Hebei and surrounding provinces: based on constructed MRIO Model显示文摘The interprovincial trade embodied carbon emissions plays an important role in the national emission reduction target among China's provinces. Furthermore, it will affect the smooth start-up of the national carbon trade market as well as the implementation of targets in 2030 for dealing with the climate change. Based on constructed MRIO model, this paper analyzes the embodied carbon emission trade flows among Beijing, Tianjin, Hebei and surrounding regions such as Shanxi, Shaanxi, and Inner Mongolia. The results indicate that six provinces have formed different patterns of carbon trade balance, where Beijing, Tianjin, and Hebei provinces are in a deficit position, while the other three provinces are in a surplus position.Beijing, Tianjin, and Hebei have transferred part of the carbon emissions to the other three provinces, which shows greater heterogeneity among various provinces and provincial different sectors. On basis of the conclusions, this paper puts forward some suggestions on provincial decomposition, responsibility distribution, and provincial collaborative reduction for national emission reduction targets. | Jianhui Cong Qingyan Liu Jidong Kang Wenju Li Xiaopei Wang Man Li | 2017 | Chinese Journal of Population,Resources and Environment2017，15，1： | 4 |
| 9 | Multi-objective optimization of building design for life cycle cost and C0_(2) emissions:A case study of a low-energy residential building in a severe cold climate显示文摘Currently,building construction and operation are responsible for 36%of global final energy usage and nearly 40%of energy-related carbon dioxide(CO_(2))emissions.From the sustainable development perspective,it is crucial to consider the impact of construction material on the achievement of life cycle benefits.This study proposed a simulation-based multi-objective optimization method to minimize both life cycle cost and CO_(2) emissions of buildings.We built an energy simulation model with hybrid ventilation and light-dimming control in EnergyPlus based on an operational passive residential building in a severe cold climate.Next,this investigation selected insulation thickness,window type,window-to-wall ratio,overhang depth and building orientation as design variables.The study ran parametric simulations to establish a database and then used artificial neural network models to correlate the design variables and the objective functions.Finally,we used the multi-objective optimization algorithm NSGA-Ⅱ to search for the optimal design solutions.The results showed potential reductions of 10.9%-18.9%in life cycle cost and 13.5%-22.4%in life cycle CO_(2) emissions compared with the initial design.The results indicated that the optimization approach in this study would improve building performance.The optimal values of the design variables obtained in this study can guide designers in meeting economic and environmental targets in passive buildings. | Qingwen Xue Zhaojun Wang Qingyan Chen | 2022 | Building Simulation2022，15，1： | 4 |
| 10 | Effects of “Bioactive” amino acids leucine, glutamate, arginine and tryptophan on feed intake and mRNA expression of relative neuropeptides in broiler chicks显示文摘Feed intake control is vital to ensuring optimal nutrition and achieving full potential for growth and development in poultry. The aim of the present study was to investigate the effects of L-leucine, L-glutamate, L-tryptophan and L-arginine on feed intake and the mRNA expression levels of hypothalamic Neuropeptide involved in feed intake regulation in broiler chicks. Leucine, glutamate, tryptophan or arginine was intra-cerebroventricularly (ICV) administrated to 4d-old broiler chicks respectively and the feed intake were recorded at various time points. Quantitative PCR was performed to determine the hypothalamic mRNA expression levels of Neuropeptide Y (NPY), agouti related protein (AgRP), pro-opiomelanocortin (POMC), melanocortin receptor 4 (MC4R) and corticotrophin releasing factor (CRF). Our results showed that ICV administration of L-leucine (0.15 or 1.5 μmol) significantly (P<0.05) increased feed intake up to 2 h post-administration period and elevated both hypothalamic NPY and AgRP mRNA expression levels. In contrast, ICV administration of L-glutamate (1.6μmol) significantly (P<0.05) decreased feed intake 0.25, 0.5 and 2 h post-injection, and increased hypothalamic CRF and MC4R mRNA expression levels. Meanwhile, both L-tryptophan (10 or 100μg) and L-arginine (20 or 200μg) had no significant effect on feed intake. These findings suggested that L-leucine and L-glutamate could act within the hypothalamus to influence food intake, and that both orexigenic and anorexigenic Neuropeptide genes might contribute directly to these effects. | Songbo Wang Paul Khondowe Shengfeng Chen Jianjian Yu Gang Shu Xiaotong Zhu Lina Wang Ping Gao Qianyun Xi Yongliang Zhang Qingyan Jiang | 2012 | Journal of Animal Science and Biotechnology2012，3，4： | 3 |
| 11 | Effect of diacylglycerol acyltransferase 2overexpression in 3T3-L1 is associated to an increase in mono-unsaturated fatty acid accumulation显示文摘Background:Fatty acid(FA) composition is the most important parameter affecting the flavor and nutritional value of the meat.The final and the only committed step in the biosynthesis of triglycerides is catalyzed by diacylglycerol acyltransferase 2(DGAT2).The role of DGAT2 in lipid accumulation has been demonstrated in adipocytes,However,little is known about the effect of DGAT2 on the FA composition of these cells.Methods:To investigate the role of DGAT2 in regulating lipid accumulation,FA composition and the expression of adipogenic genes,we cloned the open reading frame of the porcine DGAT2 gene and established 3T3-L1 cells that overexpressed DGAT2.Cells were then cultured in differentiation medium(DM) without FA,with a mixture of FAs(FA-DM),or containing a ^(13)C stable isotope-labeled FA mixture(IFA-DM).The FA composition of adipocytes was analyzed by gas chromatography-mass spectrometry and gas chromatography-isotope ratio mass spectrometry.Quantitative PCR and western blotting were employed to detect expression of adipogenic genes in 3T3-L1 adipocytes cultured with FA-DM for 12 d.Results:The triacylglyceride(TAG) content was significantly higher in 3T3-L1 adipocytes overexpressing DGAT2 than in control cells.When cultured in DM or FA-DM for 12 d,cells overexpressing DGAT2 showed a higher proportion of unsaturated FAs(C16:1 and C18:1).However,when cells overexpressing DGAT2 were cultured with FA-DM for30 min,the FA composition was almost identical to that of controls.Further,the proportion of stable isotope-labeled FAs were similar in 3T3-L1 adipocytes overexpressing DGAT2 and control cells cultured in IFA-DM for 12 d.These results collectively indicate that the higher proportion of mono-unsaturated FAs,C16:1 and C18:1,may originate from de novo FA synthesis but not from the uptake of specific FAs from the medium.This hypothesis is further supported by evidence that both mRNA and protein expression of genes involved in FA synthesis(ACACA,FASN,SCD1,and A-FABP)were significantly higher in cells overexpressing DGAT2 than in control cells.Conclusions:In conclusion,our study revealed that TAG accumulation,the proportion of MUFAs,and the expression of adipogenic genes were higher in 3T3-L1 cells overexpressing DGAT2 than in control cells. | Zhiqi Zhang Gang Shu Xiaotong Zhu Junming Guo Han Cai Songbo Wang Lina Wang Ping Gao Qianyun Xi Yongliang Zhang Li Yuan Qingyan Jiang | 2014 | Journal of Animal Science and Biotechnology2014，5，4： | 3 |
| 12 | Response of PM_(2.5)-bound elemental species to emission variations and associated health risk assessment during the COVID-19 pandemic in a coastal megacity显示文摘The coronavirus(COVID-19)pandemic is disrupting the world from many aspects.In this study,the impact of emission variations on PM_(2.5)-bound elemental species and health risks associated to inhalation exposure has been analyzed based on real-time measurements at a remote coastal site in Shanghai during the pandemic.Most trace elemental species decreased significantly and displayed almost no diel peaks during the lockdown.After the lockdown,they rebounded rapidly,of which V and Ni even exceeded the levels before the lockdown,suggesting the recovery of both inland and shipping activities.Five sources were identified based on receptor modeling.Coal combustion accounted for more than 70%of the measured elemental concentrations before and during the lockdown.Shipping emissions,fugitive/mineral dust,and waste incineration all showed elevated contributions after the lockdown.The total non-carcinogenic risk(HQ)for the target elements exceeded the risk threshold for both children and adults with chloride as the predominant species contributing to HQ.Whereas,the total carcinogenic risk(TR)for adults was above the acceptable level and much higher than that for children.Waste incineration was the largest contributor to HQ,while manufacture processing and coal combustion were the main sources of TR.Lockdown control measures were beneficial for lowering the carcinogenic risk while unexpectedly increased the non-carcinogenic risk.From the perspective of health effects,priorities of control measures should be given to waste incineration,manufacture processing,and coal combustion.A balanced way should be reached between both lowering the levels of air pollutants and their health risks. | Guochen Wang Kan Huang Qingyan Fu Jia Chen Juntao Huo Qianbiao Zhao Yusen Duan Yanfen Lin Fan Yang Wenjie Zhang Hao Li Jian Xu Xiaofei Qin Na Zhao Congrui Deng | 2022 | Journal of Environmental Sciences2022，34，12： | 2 |
| 13 | Synthesis of Ag-SiO_2 composite nanospheres and their catalytic activity显示文摘A simple,mild,and time-saving method is employed to synthesize Ag-SiO2 composite nanospheres with Ag nanoparticles uniformly distributed on the surface of SiO2 nanoparticles.The chemical elements and the morphology of Ag-SiO2 composite nanospheres were analyzed with transmission electron microscopy(TEM),X-ray power diffraction(XRD),and X-ray photoelectron spectroscopy(XPS).On the surface of Ag-SiO2 composite nanospheres,silane coupling agent(KH-550)is introduced as an intermediary to connect the surfaces of SiO2 nanospheres and Ag nanoparticles,which is also helpful for avoiding the aggregation of Ag nanoparticles.It is found that Ag-SiO2 composite nanospheres have very good catalytic properties for the reduction of organic dyes,which may have potential application in wastewater treatment. | HAN QingYan LI GuiAn WANG DeXuan HE EnJie DONG Jun GAO Wei LI JunNa LIU TingZhuo ZHANG ZhongYue ZHENG HaiRong | 2014 | Science China Chemistry2014，57，6： | 2 |
| 14 | Development and prospect of near-field optical measurements and characterizations显示文摘扫描近地的光显微镜学(SNOM ) 是在 nano 光的大小和描述的一个理想的试验性的测量系统。除有在衍射限制以外的分辨率的显微镜学以外,有纳米分辨率的分光镜和有新奇表演的另外的仪器为在 nano 光学和 nanophotonics 的研究是不可缺少的。这篇论文考察发展中的历史近地光(NFO ) 测量方法并且在未来预见它的前景。NFO 大小的开发通过了四个阶段,包括有超级分辨率,近地的光谱学, nanooptical 参数的大小,和近地的相互作用的察觉的光成像。为每个阶段,研究目的,工艺的性质和应用程序,领域被讨论。 | Jia WANG Qingyan WANG Mingqian ZHANG | 2012 | Frontiers of Optoelectronics2012，5，2： | 2 |
| 15 | Use of laser speckle contrast imaging to reveal changes in temperature and blood perfusion in the skin of healthy subjects after administration of heated moxa sticks and Daiwenjiu ointment显示文摘OBJECTIVE: To investigate the influence of heated moxa sticks( 'moxibustion') and Daiwenjiu ointment(DO) on changes in temperature and blood perfusion volume on the skin of the backs of healthy subjects.METHODS: DO was spread on the left side of the body, and the right side of the body was treated with a heated moxa stick. Images denoting blood perfusion and body temperature were collected 7-8 cm lateral to the spinous process of the sixth thoracic vertebra using laser speckle contrast imaging(LSCI). Data obtained from eight-frame images were analyzed and used to calculate the mean blood perfusion volume. Simultaneously,blood-perfusion images were collected from the body surface and used to compare the change in blood flow on the body surface and the actual position of imaging.RESULTS: After moxibustion, a rapid increase in blood perfusion volume and body temperature was noted in the local skin surface. The maximum blood perfusion volume and body temperature was noted at 20 min(P<0.05). At 80-110 min after the spreading of DO, a gradual increase was noted in blood perfusion volume(P<0.05) and body temperature(P<0.05) compared with the baseline level. The maximum blood perfusion volume was at 110 min.CONCLUSION: Using LSCI, these data revealed a rapid and sharp increase in blood perfusion volume and body temperature after treatment with moxibustion, but the respective changes seen in the DO group were gradual and moderate. | Qingyan Xu Jinsheng Yang Liang Wang Zi Deng Yingying Wang Li Yang Peng Wu Liang Li | 2014 | Journal of Traditional Chinese Medicine2014，34，4： | 2 |
| 16 | Electronic structure of exfoliated millimeter-sized monolayer WSe2 on silicon wafer显示文摘The mono layer WSe2 is in teresting and important for future application in nanoelectronics,spintronics and valleytronics devices,because it has the largest spin splitting and Ion gest valley coherence time among all the known monolayer transition-metal dichalcogenides(TMDs).Toobtain the large-area monolayer TMDs'crystal is the first step to manu facture scalable and high-performance electronic devices.In this letter,we have successfully fabricated millimeter-sized mono layer WSe2 single crystals with very high quality,based on our improved mecha nicalexfoliation method.With such superior samples,using standard high resolution angle-resolved photoemission spectroscopy,we didcomprehe nsive electronic band structure measurements on our mono layer WSe2.The overall band features point it to be a 1.2 eV direct bandgap semico nductor.Its spin splitting of the valence band at K point is found as 460 meV,which is 30 meV less than the corresponding band splitting in its bulk counterpart.The effective hole masses of valence bands are determined as 2.344 me atГ,and 0.529 me as well as 0.532 meat K for the upper and lower branch of splitting ban ds,respectively.And screening effect from substrate is shown to substa ntially impact onthe electronic properties.Our results provide importa nt insights into band structure engineering in mono layer TMDs.Our mono layer WSe2 crystals may constitute a valuable device platform. | Wenjuan Zhao Yuan Huang Cheng Shen Cong Li Yongqing Cai Yu Xu Hongtao Rong Qiang Gao Yang Wang Lin Zhao Lihong Bao Qingyan Wang Guangyu Zhang Hongjun Gao Zuyan Xu Xingjiang Zhou Guodong Liu | 2019 | Nano Research2019，12，12： | 2 |
| 17 | Comparable re- suits between standardization methods and regression analysis in predicting mortality rate among samples with bums 显示文摘 | Xiao jie Meng Qingyan Wang Yaun Zheng | 2003 | Bums2003，29，3： | 1 |
| 18 | Memory and behavior-related problems of patients with neurocognitive disorders and the attitudes of their caregivers显示文摘Objective:The purpose of this study was to investigate the memory and behavior-related problems of patients with neurocognitive disorders and the attitudes of their caregivers so as to provide an effective basis for nursing interventions against such problems.Methods:The subjects were selected from patients who were under treatment or short-term hospitalization between April 2011 and March 2012.One hundred fifty-three patients with neurocognitive disorders and their major caregivers were selected from 9 grade 3 Class A hospitals of Hunan Province.The Revised Memory and Behavior Problems Checklist(RMBPC)was used to measure the memory and behavior-related problems of patients with neurocognitive disorders and the influence on their caregivers.The occurrence of different memory and behavior-related prob-lems and the distress on their caregivers was compared.Results:The RMBPC investigation showed that among 153 patients and their caregivers,152(99.3%)had memory-related problems,137(89.5%)had depression,and 136 patients(88.9%)had destructive behaviors.The incidence of memory-related problems was higher than depression and destructive behaviors(P<0.01).Caregivers bore more distress when encountering destructive behaviors(1.95±1.13 points)than memory-related problems and depression(0.91±0.76 points and 0.89±0.85 points;P<0.01).Curve fitting was used to analyze the relationship between the number of memory and behavior-related problems and the distress on their caregivers.A curve correlation existed between the two factors(the recorded maximum value of the Cubic equation curve was 0.278,F=229.212,P<0.05).Conclusion:Among patients with neurocognitive disorders,memory-related problems had the highest incidence,while the caregivers bore the strongest distress when encountering destructive behaviors,thus interventions should be conducted in consideration of patient memory and behavior-related problems,and caregivers’attitude to further reduce caregiver burden. | Qingyan Wang Fen Jiang Sanmei Chen Siyuan Tang | 2013 | Family Medicine and Community Health2013，1，4： | 1 |
| 19 | Mechanism of formation of the heaviest pollution episodeever recorded in the Yangtze River Delta,China 显示文摘 | FU Qingyan ZHUANG Guoshun WANG Jing | 2008 | Atmos Environ2008，42，： | 1 |
| 20 | Maternal genetic history of ancient Tibetans over the past 4000 years显示文摘The settlement of the Tibetan Plateau epitomizes human adaptation to a high-altitude environment that poses great challenges to human activity.Here,we reconstruct a 4000-year maternal genetic history of Tibetans using 128 ancient mitochondrial genome data from 37 sites in Tibet.The phylogeny of haplotypes M9a1a,M9a1b,D4g2,G2a’c,and D4i show that ancient Tibetans share the most recent common ancestor with ancient Middle and Upper Yellow River populations around the Early and Middle Holocene.In addition,the connections between Tibetans and Northeastern Asians vary over the past 4000 years,with a stronger matrilineal connection between the two during 4000 BPe3000 BP,and a weakened connection after 3000 BP,that are coincident with climate change,followed by a reinforced connection after the Tubo period(1400 BPe1100 BP).Besides,an over 4000-year matrilineal continuity is observed in some of the maternal lineages.We also find the maternal genetic structure of ancient Tibetans is correlated to the geography and interactions between ancient Tibetans and ancient Nepal and Pakistan populations.Overall,the maternal genetic history of Tibetans can be characterized as a long-term matrilineal continuity with frequent internal and external population interactions that are dynamically shaped by geography,climate changes,as well as historical events. | Ganyu Zhang Can Cui Shargan Wangdue Hongliang Lu Honghai Chen Lin Xi Wei He Haibing Yuan Tinley Tsring Zujun Chen Feng Yang Tashi Tsering Shuai Li Norbu Tashi Tsho Yang Yan Tong Xiaohong Wu Linhui Li Yuanhong He Peng Cao Qingyan Dai Feng Liu Xiaotian Feng Tianyi Wang Ruowei Yang Wanjing Ping Ming Zhang Xing Gao Yichen Liu Wenjun Wang Qiaomei Fu | 2023 | Journal of Genetics and Genomics2023，50，10： | 1 |
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