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| 1 | 成都市大学生男男性行为人群艾滋病性病高危行为现状调查显示文摘[目的]了解成都市大学生男男性行为(MSM)人群性行为现状,为制定高危人群防治策略提供依据。[方法]采取'网络调查'和传统'滚雪球'调查相结合的方法对成都市大学生MSM人群性行为进行调查,所有数据使用SPSS13.0进行分析。[结果]回收有效问卷共617份。调查对象平均年龄(21.51±2.27)岁。62.4%的受访者自我认同为同性恋,28.8%的受访者自我认同为双性恋。89.5%的受访者认为同性恋是正常性行为,21.5%的受访者认为自己以后不会与异性结婚,有21.4%的受访者已经与异性发生过性行为。41.8%的受访者近1个月与固定性伴每次肛交都使用安全套,62.9%的受访者与固定性伴最近1次肛交时使用了安全套;56.7%的受访者近1个月与非固定性伴每次肛交都使用安全套,25.1%受访者与非固定性伴最近1次肛交时未使用安全套。艾滋病性病知识来源于综合网站和同志网站分别是59.8%和42.5%,来源于朋友和同志工作组分别为24.5%和15.4%。[结论]高危行为在大学生MSM群体中存在,该群体大多数同志并未意识到所面临的HIV及性病威胁。未来的干预应重点增加对大学生男同性恋群体自我认同及心理支持的关注,有针对性的开发安全套推广策略以及创新性的动员大学生同志开展与其环境和群体文化相适应的干预活动形式。 | 邓斌 江华 王文渊 Charles Damien Lu Sean Robert Dickson 赖文红 杨浩 刘毅 | 2010 | 现代预防医学2010,37,8: | 29 |
| 2 | Platelets generated from human embryonic stem cells are functional in vitro and in the microcirculation of living mice显示文摘 | Shi-Jiang Lu Feng Li Hong Yin Qiang Feng Erin A Kimbrel Eunsil Hahm Jonathan N Thon Wei Wang Joseph E ltaliano Jaehyung Cho Robert Lanza | 2011 | Cell Research2011,21,3: | 14 |
| 3 | CO_2 Density-Raman Shift Relation Derived from Synthetic Inclusions in Fused Silica Capillaries and Its Application显示文摘The densities of CO_2 inclusions in minerals are commonly used to determine the crystallizing conditions of the host minerals.However,conventional microthermometry is difficult to apply for inclusions of small size(<5-10μm) or low density.Raman analysis is an alternative method for determining CO_2 density,provided that the CO_2 density-Raman shift relation is known.This study aims to establish this CO_2 density-Raman shift relation by using CO_2 inclusions synthesized in fused silica capillaries.By using this newly-developed synthetic technique,we formed pure CO_2 inclusions,and their densities were determined by microthermometry.The Raman analysis showed that the relation between CO_2 density(D in g/cm3) and the separations(△in cm^(-1)) between the two main bands(i.e.Fermi diad bands) in CO_2 Raman spectra can be represented by a cubic equation:D (g/cm^3)=0.74203(-0.019⊿~3+5.90332⊿~2-610.79472⊿+21050.30165)-3.54278(r^2=0.99920).Our calculated D value for a given⊿ is between those obtained from two previously-reported equations,which were derived from different experimental methods.An example was given in this study to demonstrate that the densities of natural CO_2 inclusions that could not be derived from microthermometry could be determined by using our method. | SONG Yucai CHOU I'Ming HU Wenxuan Burruss ROBERT LU Wanjun | 2009 | Acta Geologica Sinica(English Edition)2009,83,5: | 9 |
| 4 | Subclinical atherosclerosis in northern and southern China: the Chinese paradox显示文摘背景冠的心疾病(CHD ) 的发生是更高的在北比在南部的中国,然而,在传统的 CHD 的差别冒险的,解释这。没有学习在可以帮助在发生解释差别的无临床症状的动脉粥样硬化检验了差别。这研究为在北、南部的中国之间的石灰化用冠的计算断层摄影术(CT ) 在无临床症状的动脉粥样硬化检验了这些差别。我们在一个大多中心选择了参加者的一件随机的样品的方法为冠的钙在一个北城市(诺思) 里扫描的进行中的流行病的学习(北京, n = 49 ) 并且在二个南部的城市(南方) 里(上海, n = 50,并且广州, n = 50 ) 。从三个领域中心的参加者(意味着年龄 67 年) 经历了用动脉粥样硬化扫描的多种族的学习为冠的钙测量扫描的冠的风险因素评估和心脏的 CT 协议。结果调整了在诺思中国(北京) 的转变木头的冠的动脉钙 20 是 3.1 +/-0.4 并且在华南(上海和广州) 是 2.2 +/- 0.3 (P = 0.04 ) 。为北京的北城市的吝啬的钙分数比广州的南部的城市的高三倍(P = 0.01 ) 并且比为上海的南部的城市高 2.5 倍(P = 0.03 ) 。结论无临床症状的动脉粥样硬化的程度在广州和上海的二个南部的城市里比那在北京的北城市里是显著地更高的,甚至在为标准心脏的风险因素调整以后。这发现建议标准风险因素充分不在临床的 CHD 发生解释北方南方差别。 | Jie Huang Yang-Feng Wu Xiao-Qing Liu Ding Ding Lian-Cheng Zhao Bin Lu Xian Li Nathan D Wong Laurie D Dustin Stanley P Azen Robert C Detrano | 2011 | Journal of Geriatric Cardiology2011,8,2: | 7 |
| 5 | A tale of worldwide success:Behind the scenes of Carex(Cyperaceae)biogeography and diversification显示文摘The megadiverse genus Carex(c.2000 species,Cyperaceae)has a nearly cosmopolitan distribution,displaying an inverted latitudinal richness gradient with higher species diversity in cold-temperate areas of the Northern Hemisphere.Despite great expansion in our knowledge of the phylogenetic history of the genus and many molecular studies focusing on the biogeography of particular groups during the last few decades,a global analysis of Carex biogeography and diversification is still lacking.For this purpose,we built the hitherto most comprehensive Carex-dated phylogeny based on three markers(ETS-ITS-matK),using a previous phylogenomic Hyb-Seq framework,and a sampling of two-thirds of its species and all recognized sections.Ancestral area reconstaiction,biogeographic stochastic mapping,and diversification rate analyses were conducted to elucidate macroevolutionary biogeographic and diversification patterns.Our results reveal that Carex originated in the late Eocene in E Asia,where it probably remained until the synchronous diversification of its main subgeneric lineages during the late Oligocene.E Asia is supported as the cradle of Carex diversification,as well as a< | Santiago Martin-Bravo Pedro Jimenez-Mejias Tamara Villaverde Marcial Escudero Marlene Hahn Daniel Spalink Eric H.Roalson Andrew L.Hipp the Global Carex Group Carmen Benitez-Benitez Leo P.Bruederle Elisabeth Fitzek Bruce A.Ford Kerry A.Ford Mira Gamer Sebastian Gebauer Matthias H.Hoffmann Xiao-Feng Jin Isabel Larridon Etienne Ldveilld-Bourret Yi-Fei Lu Modesto Luceno Enrique Maguilla Jose Ignacio Marquez-Corro Monica Miguez Robert Naczi Anton A.Reznicek Julian R.Starr | 2019 | Journal of Systematics and Evolution2019,57,6: | 6 |
| 6 | Design and baseline data of a populationbased metabonomics study of eye diseases in eastern China: the Yueqing Ocular Diseases Investigation显示文摘Background:China is undergoing a massive transition toward an urban and industrial economy.These changes will restructure the demographics and economy which will eventually influence the future patterns of disease.The risk factors of vision-impairing eye diseases remain ambiguous and poorly understood.Metabolomics is an ideal tool to understand and shed light on the ocular disease mechanisms for earlier treatment.This article aims to describe the design,methodology and baseline data of the Yueqing Ocular Diseases Investigation(YODI),a developed county population-based study to determine the prevalence and primary causes of visual impairment;also with metabonomics analysis we aimed to identify,predict and suggest some preventive biomarkers that cause blindness.Methods:A population-based,cross-sectional study.Randomized clustering sampling was used to identify adults aged 50 years and older in Xiangyang Town,Yueqing county-level City.The interviews covered demographic,behavioral,ocular risk factors and mental health state.The ocular examination included visual acuity,autorefraction,intraocular pressure,anterior and posterior segment examinations,fundus photography,retinal tomography and angiography,and visual field testing.Anthropometric measurements included height and weight,waist and hip circumference,blood pressure,pulse rate,electrocardiogram,and abdominal ultrasound scan.A venous blood sample was collected for laboratory tests and metabonomics studies.Results:Of the 5319 individuals recruited for the YODI,4769(89.7%)subjects were enrolled for analyses.The median age was 62.0 years,and 45.6%were male.The educational level of illiteracy or semi-illiteracy,primary,middle and high school or above was 29.8%,45.5%,20.1%,and 3.3%,respectively.Majority of the participants were female,younger,and less educated when compared with nonparticipants.The average body mass index and waist-hip ratios were 24.4±3.4 kg/m^(2) and 0.9±0.1 respectively.Blood sample collection reached a sample size of 1909(479 from subjects with selfreported diabetes and 1430 from one-third of the 4290 subjects without self-reported diabetes).Conclusions:The YODI provides population-based data with a high response rate(89.7%)on the prevalence and primary causes of major vision-impairing eye diseases in developed county areas in eastern China.Metabonomics analysis from YODI will provide further association of metabolic characteristics with the visual impairment eye diseases.The risk prediction model could be created and has the potential to be generalized to developed eastern areas in China for prevention. | Yuxuan Deng Yuanbo Liang Sigeng Lin Liang Wen Jin Li Yue Zhou Meixiao Shen Jingwei Zheng Kemi Feng Yanting Sun Kwapong Willaim Robert Jia Qu Fan Lu | 2020 | Eye and Vision2020,7,1: | 4 |
| 7 | 中国男男性行为群体HIV干预面临的挑战:基于社区和已发表证据的循证评价显示文摘目的对中国男男性行为人群中艾滋病干预面临的挑战进行初步循证评价。方法社区证据来源于对相关工作者、专家的访谈以及近5年对国内同志艾滋病防治活动的参与经验。已发表文献的证据,通过确定检索策略、入选标准和特定关键词,采用系统化的文献检索,收集与研究目的有关的文献,检索数据库包括中国生物医学文献数据库(1996-2007)、MEDLINE(1996-2007)及相关网页。结果以社区组织为基础和以'扩散理论'为指导的干预模式在知识传播、行为改变方面面临巨大挑战。表现为传递的教育信息质量低、教育娱乐化、安全套可及性不足,心理社会支持重视不够等问题。此外,普遍存在的滥用公共卫生术语'MSM'的现象。缺乏对MSM群体的社会及文化特征的研究。结论中国MSM群体中的艾滋病防治策略需要做大的调整和改进。需要建立高效的媒体反应机制以消除错误信息,应在政策上纳入反对性倾向歧视,大力倡导感染者参与,鼓励对MSM中不同群体的社会、心理需求进行更多研究,民间组织在促进男同性性行为者的自我认同、心理支持方面进行更多工作。应将循证项目评估原理和方法整合成项目评估体系。 | 江华 Charles Damien Lu 魏伟 张建新 顾仪 Sean Robert Dickson 江晖 | 2009 | 预防医学情报杂志2009,25,7: | 4 |
| 8 | 硝酸根对颗粒状铁降解三氯乙烯的影响(英文)显示文摘为研究硝酸根对颗粒状铁降解三氯乙烯的影响,进行了柱实验和相应的反应铁腐蚀电位测定。在硝酸根离子存在条件下,铁的腐蚀电位相应升高,系统条件也因之发生变化,导致钝性的铁氧化物在铁表面生成。因而,三氯乙烯和硝酸根离子降解速率明显减小, 并且降解速率减小的程度与硝酸根离子的浓度成比例。当污染液流过反应柱时,硝酸根离子与铁反应, 被还原为氨根离子。该反应造成硝酸根离子的浓度梯度,使钝化区在柱中上移,从而影响了三氯乙烯的降解曲线。与三氯乙烯单独与铁反应相比,当含4 7 mg/L硝酸根的三氯乙烯溶液流经反应柱170 孔隙体积后,降解50% 三氯乙烯所需的时间(t50) 从小于4 h增加到大于10 h;而当三氯乙烯溶液中加入100 mg/L硝酸根离子,仅17 孔隙体积溶液流经反应柱后,三氯乙烯降解t50就已大于14 h。研究结果表明,由于硝酸根离子对铁的腐蚀电位和铁表面氧化膜的不利作用,在处理靶污染物为高浓度硝酸根离子和三氯乙烯共同污染的地下水时,铁渗透反应隔栅不是最佳选择。如果靶污染物中硝酸根离子浓度比较低,则在设计铁隔栅时应考虑到硝酸根离子造成的不利因素,相应增加铁墙的厚度,从而确保三氯乙烯的降解效果。 | Qiong LU Lai GUI Robert W. GILLHAM | 2005 | 地学前缘2005,12,U04: | 4 |
| 9 | Metabolic syndrome and coronary artery calcification: a community-based natural population study显示文摘 | CAO Hui-li CHEN Xiong-biao LU Jin-guo HOU Zhi-hui TANG Xiang GAO Yang YU Fang-fang JIANG Shi-liang ZHAO Lian-cheng LI Ying Matthew J Budoff Robert Detrano LU Bin | 2013 | Chinese Medical Journal2013,,24: | 4 |
| 10 | Utility of a novel serum tumor biomarker HE4 in patients with endometrioid adenocarcinoma of the uterus显示文摘 | Richard G. Moore Amy K. Brown M. Craig Miller Donna Badgwell Zhen Lu W. Jeffrey Allard C.O. Granai Robert C. Bast Karen Lu | 2008 | Gynecologic Oncology2008,,2: | 3 |
| 11 | Lack of hepcidin expression attenuates steatosis and causesfibrosis in the liver显示文摘AIM: To investigate the role of key iron-regulatory protein, hepcidin in non-alcoholic fatty liver disease(NAFLD). METHODS: Hepcidin(Hamp1) knockout and floxed control mice were administered a high fat and high sucrose(HFS) or a regular control diet for 3 or 7 mo. Steatosis, triglycerides, fibrosis, protein and gene expression in mice livers were determined by histological and biochemical techniques, western blotting and realtime polymerase chain reaction. RESULTS: Knockout mice exhibited hepatic iron accumulation. Despite similar weight gains, HFS feeding induced hepatomegaly in floxed, but not knockout, mice. The livers of floxed mice exhibited higher levels of steatosis, triglycerides and c-Jun N-terminal kinase(JNK) phosphorylation than knockout mice. In contrast, a significant increase in fibrosis was observed in knockout mice livers within 3 mo of HFS administration. The hepatic gene expression levels of sterol regulatoryelement-binding protein-1c and fat-specific protein-27, but not peroxisome proliferator-activated receptoralpha or microsomal triglyceride transfer protein, were attenuated in HFS-fed knockout mice. Knockout mice fed with regular diet displayed increased carnitine palmitoyltransferase-1a and phosphoenolpyruvate carboxykinase-1 but decreased glucose-6-phosphatase expression in the liver. In summary, attenuated steatosis correlated with decreased expression of lipogenic and lipid storage genes, and JNK phosphorylation. Deletion of Hamp1 alleles per se modulated hepatic expression of beta-oxidation and gluconeogenic genes. CONCLUSION: Lack of hepcidin expression inhibits hepatic lipid accumulation and induces early development of fibrosis following high fat intake. Hepcidin and iron may play a role in the regulation of metabolic pathways in the liver, which has implications for NAFLD pathogenesis. | Sizhao Lu Robert G Bennett Kusum K Kharbanda Duygu Dee Harrison-Findik | 2016 | World Journal of Hepatology2016,8,4: | 3 |
| 12 | Implementing the communication for development strategy to improve knowledge and coverage of measles vaccination in western Chinese immunization programs:a before-and-after evaluation显示文摘Background:Communication for Development(C4D)is a strategy promoted by the United Nations Children’s Fund to foster positive and measurable changes at the individual,family,community,social,and policy levels of society.In western China,C4D activities have previously been conducted as part of province-level immunization programs.In this study,we evaluated the association of C4D with changes in parental knowledge of immunization services,measles disease,and measles vaccine,and changes in their children’s measles vaccine coverage.Methods:From April 2013 to April 2014,C4D activities were implemented as part of provincial immunization programs in the Inner Mongolia,Guangxi,Chongqing,Guizhou,Tibet,Shaanxi,Gansu,Ningxia,and Qinghai provinces.We used a before-and-after study design and employed face-to-face interviews to assess changes in parental knowledge and vaccination coverage.Results:We surveyed 2107 households at baseline and 2070 households after 1 year of C4D activities.Following C4D,95%of caregivers were aware of the vaccination record check requirement for entry into kindergarten and primary school;80%of caregivers were aware that migrant children were eligible for free vaccination;more than 70%of caregivers knew that measles is a respiratory infectious disease;and 90%of caregivers knew the symptoms of measles.Caregivers’willingness to take their children to the clinic for vaccination increased from 51.3%at baseline to 67.4%in the post-C4D survey.Coverage of one-dose measles-containing vaccine(MCV)increased from 83.8%at baseline to 90.1%after C4D.One-dose MCV coverage was greater than 95%in the Guangxi,Shaanxi,and Gansu provinces.Two-dose MCV coverage increased from 68.5 to 77.6%.House-to-house communication was the most popular C4D activity among caregivers(91.6%favoring),followed by posters and educational talks(64.8 and 49.9%favoring).Conclusions:C4D is associated with increased caregiver knowledge about measles,increased willingness to seek immunization services for their children,and increased measles vaccination coverage.Tailored communication strategies based on insights gained from these analyses may be able to increase vaccination coverage in hard-to-reach areas.C4D should be considered for larger scale implementation in China. | Ming Lu Yao-Zhu Chu Wen-Zhou Yu Robert Scherpbier Yu-Qing Zhou Xu Zhu Qi-Ru Su Meng-Juan Duan Xuan Zhang Fu-Qiang Cui Hua-Qing Wang Yi-Biao Zhou Qing-Wu Jiang | 2017 | Infectious Diseases of Poverty2017,6,1: | 3 |
| 13 | Management of rice straw with relay cropping of Chinese milk vetch improved double-rice cropping system production in southern China显示文摘Improved utilization of rice(Oryza sativa L.)straw and Chinese milk vetch(Astragalus sinicus L.,vetch)has positive effects on rice production.So far,few studies have investigated the productivity of vetch under different residue management practices in double-rice cropping system.The effects of rice straw on the growth and nutrient accumulation of vetch across seven years(2011–2017)and the subsequent effects of rice straw and vetch on two succeeding rice crops in a vetch–rice–rice cropping system,with the vetch established by relay cropping,were examined.The seven-year double-rice experiment consisted of the following treatments:(1)100%chemical fertilizer(F-F100);(2)only vetch without chemical fertilizer(M-Con);(3)80%chemical fertilizer plus vetch plus a low-cutting height(low-retained stubble)with the removal of straw(M-F80);(4)80%chemical fertilizer plus vetch plus a low-cutting height with the retention of straw(M-F80-LR);(5)80%chemical fertilizer plus vetch plus a high-cutting height(high-retained stubble)with the retention of straw(M-F80-HR);and(6)no fertilizer(F-Con).The yields of the two rice crops after vetch were not affected by either the cutting height of stubble with retention of straw or by the management of straw(retention vs.removal)with low-cutting height of stubble.The yields of the two rice crops after vetch were significantly higher for M-F80-HR than for M-F80-LR,but the relative contributions of the high-cutting height and straw retention to the higher rice yield could not be determined in this study.The yield stability of the double-rice grain in M-F80-HR was also increased,as determined by a sustainable yield index.Significant increases in vetch biomass and nutrient uptake were observed in the fertilized treatments during the rice season compared with the unfertilized treatments.In M-F80-HR plots,improvements in the growing environment of the vetch by conserving soil water content were associated with the highest vetch biomass,nutrient uptake,and yield stability of vetch biomass.These increased nutrient inputs partially replaced the demand for chemical fertilizer and stimulated the rice yields.It can be concluded that retaining higher-cutting stubble residues with straw retention could be the best straw management practice for increasing the vetch biomass and nutrient use efficiency,thereby allowing utilization of high-cutting height with retention of straw and vetch to improve the stability of rice productivity in a double-rice cropping system. | ZHOU Xing LIAO Yu-lin LU Yan-hong Robert MREES CAO Wei-dong NIE Jun LI Mei | 2020 | Journal of Integrative Agriculture2020,19,8: | 3 |
| 14 | A framework infrageneric classification of Carex (Cyperaceae) and its organizing principles显示文摘Phylogenetic studies of Carex L.(Cyperaceae)have consistently demonstrated that most subgenera and sections are para-or polyphyletic.Yet,taxonomists continue to use subgenera and sections in Carex classification.Why?The Global Carex Group(GCG)here takes the position that the historical and continued use of subgenera and sections serves to(i)organize our understanding of lineages in Carex,(ii)create an identification mechanism to break the~2000 species of Carex into manageable groups and stimulate its study,and(iii)provide a framework to recognize morphologically diagnosable lineages within Carex.Unfortunately,the current understanding of phylogenetic relationships in Carex is not yet sufficient for a global reclassification of the genus within a Linnean infrageneric(sectional)framework.Rather than leaving Carex classification in its current state,which is misleading and confusing,we here take the intermediate steps of implementing the recently revised subgeneric classification and using a combination of informally named clades and formally named sections to reflect the current state of our knowledge.This hybrid classification framework is presented in an order corresponding to a linear arrangement of the clades on a ladderized phylogeny,largely based on the recent phylogenies published by the GCG.It organizes Carex into six subgenera,which are,in turn,subdivided into 62 formally named Linnean sections plus 49 informal groups.This framework will serve as a roadmap for research on Carex phylogeny,enabling further development of a complete reclassification by presenting relevant morphological and geographical information on clades where possible and standardizing the use of formal sectional names. | Eric H.Roalson Pedro Jiménez-Mejías Andrew L.Hipp Carmen Benítez-Benítez Leo P.Bruederle Kyong-Sook Chung Marcial Escudero Bruce A.Ford Kerry Ford Sebastian Gebauer Berit Gehrke Marlene Hahn Muhammad Qasim Hayat Mathias H.Hoffmann Xiao-Feng Jin Sangtae Kim Isabel Larridon Étienne Léveillé-Bourret Yi-Fei Lu Modesto Luceño Enrique Maguilla Jose IgnacioMárquez-Corro Santiago Martín-Bravo Tomomi Masaki Mónica Míguez Robert F.C.Naczi Anton A.Reznicek Daniel Spalink Julian R.Starr Uzma Tamara Villaverde Marcia J.Waterway Karen L.Wilson and Shu-Ren Zhang | 2021 | Journal of Systematics and Evolution2021,59,4: | 3 |
| 15 | 重塑能源-中国:能效在中国面向2050年路线图中的作用显示文摘作为《巴黎协定》承诺的一部分,中国计划在2030年左右达到二氧化碳(CO_2)排放峰值并争取尽早达峰。在研究如何实现上述减排承诺的前提下,中美研究人员组成的团队构建了一个自下而上的中国能源供需综合模型。基于该模型对比分析了两种情景的差异,即沿着当前趋势发展的参考路径情景以及'重塑能源'替代路径情景。'重塑能源'替代路径是指为满足国家需求,在2050年前最大程度地应用当前成本有效的能源效率策略和可再生能源。结果表明,如果中国走更积极的重塑能源路径,那么其二氧化碳排放量可比参考路径提前11年达峰。本文重点分析了在更积极的路径下能源效率策略对于二氧化碳减排的作用。除能源效率外,本研究还分析了燃料替换(从碳密集型燃料转向其他燃料)的减排作用。结果表明,对于重塑能源情景,能源效率提高及相关策略贡献了中国2050年二氧化碳总减排潜力的75%,而燃料替换仅占25%。为在中国实现上述具有显著成本效益的能效潜力。 | Lynn Price Nina Khanna Nan Zhou David Fridley Ali Hasanbeigi Hongyou Lu Feng Wei 戴彦德 田智宇 杨宏伟 白泉 朱跃中 熊华文 张建国 Jon Creyts Kate Chrisman Ellen Franconi Josh Agenbroad Michael Bendewald Yi Ke Robert McIntosh David Mullaney Clay Stranger Daniel Wetzel Cvrd Yee | 2018 | 科学与管理2018,38,3: | 3 |
| 16 | Subepicardial endothelial cells invade the embryonic ventricle wall to form coronary arteries显示文摘冠的动脉把血流动带到心肌肉。理解冠的动脉的发展程序提供卓见进冠的动脉疾病的治疗。多重来源被描述了为包括 proepicardium,湾穴 venosus (SV ) ,和心内膜贡献冠的动脉。然而,冠的容器的发展起源仍然在强烈学习下面。我们为学习冠的开发生产了一个新基因工具,一只 AplnCreER 老鼠在开发冠的容器明确地衬里 recombinase,它表示可诱导的 Cre。冠的开发和 AplnCreER 命运跟踪的预定正式就职的定量分析证明 subepicardial endothelial 房间(EC ) 的子孙两个都入侵紧缩的心肌层形成冠的动脉并且在表面上留下生产静脉。我们发现这些 subepicardial EC 是 intramyocardial 的主要来源在发展中的心的冠的容器。在 vitro 将生物的活组织移植于培养基中培养,试金显示这些 subepicardial EC 的多数从 SV 和中庭的心内膜,然而并非从室的心内膜产生。Apln 积极的房间的同种细胞的分析显示单个 subepicardial EC 同等地作出贡献到冠的动脉和静脉。一起,这些数据建议 subepicardial EC 是 intramyocardial 的主要来源在室的冠的动脉墙,和那冠的动脉和静脉在发展中的心有普通起源。 | Xueying Tian Tianyuan Hu Hui Zhang Lingjuan He Xiuzhen Huang Qiaozhen Liu Wei Yu Liang He Zhongzhou Yang Zhen Zhang Tao P Zhong Xiao Yang Zhen Yang Yan Yan Antonio Baldini Yunfu Sun Jie Lu Robert J Schwartz Sylvia M Evans Adriana C Gittenberger-de Groot Kristy Red-Horse Bin Zhou | 2013 | Cell Research2013,23,9: | 3 |
| 17 | Local Ablative Therapy of Oligoprogressive Disease Prolongs Disease Control by Tyrosine Kinase Inhibitors in Oncogene-Addicted Non–Small-Cell Lung Cancer显示文摘 | Andrew J. Weickhardt Benjamin Scheier Joseph Malachy Burke Gregory Gan Xian Lu Paul A. Bunn Dara L. Aisner Laurie E. Gaspar Brian D. Kavanagh Robert C. Doebele D. Ross Camidge | 2012 | Journal of Thoracic Oncology2012,,12: | 3 |
| 18 | Monitoring Greenhouses Gases over China Using Space-Based Observations Monitoring Greenhouses Gases over China Using Space-Based Observations显示文摘The atmospheric carbon dioxide(CO 2)concentration has increased to more than 405 parts per million(ppm.1 ppm=10-6 m/s 2)in 2017 due to human activities such as deforestation,land-use change and burning of fossil fuels.Although there is broad scientific consensus on the damaging consequences of the change in climate associated with increasing concentrations of greenhouse gases,fossil CO 2 emissions have continued to increase in recent years mainly from rapidly developing economies and China is now the largest emitter of CO 2 generating about 30%of all emissions globally.To allow more reliable forecast of the future state of the carbon cycle and to support the efforts for mitigation greenhouse gas emissions,a better understanding of the global and regional carbon budget is needed.Space-based measurements of CO 2 can provide the necessary observations with dense coverage and sampling to provide improved constrains on of carbon fluxes and emissions.The Chinese Global Carbon Dioxide Monitoring Scientific Experimental Satellite(TanSat)was established by the National High Technology Research and Development Program of China with the main objective of monitoring atmospheric CO 2 and CO 2 fluxes at the regional and global scale.TanSat has been successfully launched in December 2016 and as part of the Dragon programme of ESA and the Ministry of Science and Technology(MOST),a team of researchers from Europe(UK and Finland)and China has evaluated early TanSat data and contrast it against data from the GOSAT mission and models.In this manuscript,we report on retrieval intercomparisons of TanSat data using two different retrieval algorithms,on validation efforts for the Eastern Asia region using GOSAT CO 2 data and first assessments of TanSat and GOSAT CO 2 data against model calculations using the GEOS-Chem model. | Hartmut BOESCH Yi LIU Paul I PALMER Johanna TAMMINEN Jasdeep S ANAND Zhaonan CAI Ke CHE Huilin CHEN Xi CHEN Liang FENG Janne HAKKARAINEN Pauli HEIKKINEN Nikoleta KALAITZI Rigel KIVI Robert PARKER Peter SOMKUTI Jing WANG Alex WEBB Dongxu YANG Lu YAO You YI | 2020 | Journal of Geodesy and Geoinformation Science2020,3,4: | 2 |
| 19 | Fungal diversity notes 367-490:taxonomic and phylogenetic contributions to fungal taxa显示文摘This is a continuity of a series of taxonomic papers where materials are examined,described and novel combinations are proposed where necessary to improve our traditional species concepts and provide updates on their classification.In addition to extensive morphological descriptions and appropriate asexual and sexual connections,DNA sequence data are also analysed from concatenated datasets(rDNA,TEF-a,RBP2 and b-Tubulin)to infer phylogenetic relationships and substantiate systematic position of taxa within appropriate ranks.Wherever new species or combinations are being proposed,we apply an integrative approach(morphological and molecular data as well as ecological features wherever applicable).Notes on 125 fungal taxa are compiled in this paper,including eight new genera,101 new species,two new combinations,one neotype,four reference specimens,new host or distribution records for eight species and one alternative morphs.The new genera introduced in this paper are Alloarthopyrenia,Arundellina,Camarosporioides,Neomassaria,Neomassarina,Neotruncatella,Paracapsulospora and Pseudophaeosphaeria.The new species are Alfaria spartii,Alloarthopyrenia italica,Anthostomella ravenna,An.thailandica,Arthrinium paraphaeospermum,Arundellina typhae,Aspergillus koreanus,Asterina cynometrae,Bertiella ellipsoidea,Blastophorum aquaticum,Cainia globosa,Camarosporioides phragmitis,Ceramothyrium menglunense,Chaetosphaeronema achilleae,Chlamydotubeufia helicospora,Ciliochorella phanericola,Clavulinopsis aurantiaca,Colletotrichum insertae,Comoclathris italica,Coronophora myricoides,Cortinarius fulvescentoideus,Co.nymphatus,Co.pseudobulliardioides,Co.tenuifulvescens,Cunninghamella gigacellularis,Cyathus pyristriatus,Cytospora cotini,Dematiopleospora alliariae,De.cirsii,Diaporthe aseana,Di.garethjonesii,Distoseptispora multiseptata,Dis.tectonae,Dis.tectonigena,Dothiora buxi,Emericellopsis persica,Gloniopsis calami,Helicoma guttulatum,Helvella floriforma,H.oblongispora,Hermatomyces subiculosa,Juncaceicola italica,Lactarius dirkii,Lentithecium unicellulare,Le.voraginesporum,Leptosphaeria cirsii,Leptosphaeria irregularis,Leptospora galii,Le.thailandica,Lindgomyces pseudomadisonensis,Lophiotrema bambusae,Lo.fallopiae,Meliola citri-maximae,Minimelanolocus submersus,Montagnula cirsii,Mortierella fluviae,Muriphaeosphaeria ambrosiae,Neodidymelliopsis ranunculi,Neomassaria fabacearum,Neomassarina thailandica,Neomicrosphaeropsis cytisi,Neo.cytisinus,Neo.minima,Neopestalotiopsis cocoe¨s,Neopestalotiopsis musae,Neoroussoella lenispora,Neotorula submersa,Neotruncatella endophytica,Nodulosphaeria italica,Occultibambusa aquatica,Oc.chiangraiensis,Ophiocordyceps hemisphaerica,Op.lacrimoidis,Paracapsulospora metroxyli,Pestalotiopsis sequoiae,Peziza fruticosa,Pleurotrema thailandica,Poaceicola arundinis,Polyporus mangshanensis,Pseudocoleophoma typhicola,Pseudodictyosporium thailandica,Pseudophaeosphaeria rubi,Purpureocillium sodanum,Ramariopsis atlantica,Rhodocybe griseoaurantia,Rh.indica,Rh.luteobrunnea,Russula indoalba,Ru.pseudoamoenicolor,Sporidesmium aquaticivaginatum,Sp.olivaceoconidium,Sp.pyriformatum,Stagonospora forlicesenensis,Stagonosporopsis centaureae,Terriera thailandica,Tremateia arundicola,Tr.guiyangensis,Trichomerium bambusae,Tubeufia hyalospora,Tu.roseohelicospora and Wojnowicia italica.New combinations are given for Hermatomyces mirum and Pallidocercospora thailandica.A neotype is proposed for Cortinarius fulvescens.Reference specimens are given for Aquaphila albicans,Leptospora rubella,Platychora ulmi and Meliola pseudosasae,while new host or distribution records are provided for Diaporthe eres,Di.siamensis,Di.foeniculina,Dothiorella iranica,Do.sarmentorum,Do.vidmadera,Helvella tinta and Vaginatispora fuckelii,with full taxonomic details.An asexual state is also reported for the first time in Neoacanthostigma septoconstrictum.This paper contributes to a more comprehensive update and improved identification of many ascomycetes and basiodiomycetes. | Kevin D.Hyde Sinang Hongsanan Rajesh Jeewon D.Jayarama Bhat Eric H.C.McKenzie E.B.Gareth Jones Rungtiwa Phookamsak Hiran A.Ariyawansa Saranyaphat Boonmee Qi Zhao Faten Awad Abdel-Aziz Mohamed A.Abdel-Wahab Supharat Banmai Putarak Chomnunti Bao-Kai Cui Dinushani A.Daranagama Kanad Das Monika C.Dayarathne Nimali Ide Silva Asha J.Dissanayake Mingkwan Doilom Anusha H.Ekanayaka Tatiana Baptista Gibertoni Aristóteles Góes-Neto Shi-Ke Huang Subashini C.Jayasiri Ruvishika S.Jayawardena Sirinapa Konta Hyang Burm Lee Wen-Jing Li Chuan-Gen Lin Jian-Kui Liu Yong-Zhong Lu Zong-Long Luo Ishara S.Manawasinghe Patinjareveettil Manimohan Ausana Mapook Tuula Niskanen Chada Norphanphoun Moslem Papizadeh Rekhani H.Perera Chayanard Phukhamsakda Christian Richter AndréL.C.Mde A.Santiago E.Ricardo Drechsler-Santos Indunil C.Senanayake Kazuaki Tanaka T.M.D.S.Tennakoon Kasun M.Thambugala Qing Tian Saowaluck Tibpromma Benjarong Thongbai Alfredo Vizzini Dhanushka N.Wanasinghe Nalin N.Wijayawardene Hai-Xia Wu Jing Yang Xiang-Yu Zeng Huang Zhang Jin-Feng Zhang Timur S.Bulgakov Erio Camporesi Ali H.Bahkali Mohammad A.Amoozegar Lidia Silva Araujo-Neta Joseph F.Ammirati Abhishek Baghela R.P.Bhatt Dimitar Bojantchev Bart Buyck Gladstone Alves da Silva Catarina Letícia Ferreira de Lima Rafael JoséVilela de Oliveira Carlos Alberto Fragoso de Souza Yu-Cheng Dai Bálint Dima Tham Thi Duong Enrico Ercole Fernando Mafalda-Freire Aniket Ghosh Akira Hashimoto Sutakorn Kamolhan Ji-Chuan Kang Samantha C.Karunarathna Paul M.Kirk Ilkka Kytovuori Angela Lantieri Kare Liimatainen Zuo-Yi Liu Xing-Zhong Liu Robert Lücking Gianfranco Medardi Peter E.Mortimer Thi Thuong Thuong Nguyen Itthayakorn Promputtha K.N.Anil Raj Mateus A.Reck Saisamorn Lumyong Seyed Abolhassan Shahzadeh-Fazeli Marc Stadler Mohammad Reza Soudi Hong-Yan Su Takumasa Takahashi Narumon Tangthirasunun Priyanka Uniyal Yong Wang Ting-Chi Wen Jian-Chu Xu Zhong-Kai Zhang Yong-Chang Zhao Jun-Liang Zhou Lin Zhu | 2016 | Fungal Diversity2016,,5: | 2 |
| 20 | Synthesis of Flurbiprofen via Suzuki Reaction Catalyzed by Palladium Charcoal in Water显示文摘Flurbiprofen 1,优秀 nonsteroidal 反煽动性的药,在 69% 总收率在 5 步被综合。构造双性人芳基碎片的关键步成功地作为 phenylation 试剂用 sodiumtetraphenylborate 在水里经由 Pd/C-catalyzed 铃木偶合反应被完成。 | Gang LU Robert FRANZEN Xiao Jing YU You Jun XU | 2006 | Chinese Chemical Letters2006,17,4: | 2 |