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| 1 | Suppression of m6A reader Ythdf2 promotes hematopoietic stem cell expansion显示文摘 | Zhenrui Li Pengxu Qian Wanqing Shao Hailing Shi Xi C. He Madelaine Gogol Zulin Yu Yongfu Wang Meijie Qi Yunfei Zhu John M. Perry Kai Zhang Fang Tao Kun Zhou Deqing Hu Yingli Han Chongbei Zhao Richard Alexander Hanzhang Xu Shiyuan Chen Allison Peak Kathyrn Hall Michael Peterson Anoja Perera Jeffrey S. Haug Tari Parmely Hua Li Bin Shen Julia Zeitlinger Chuan He Linheng Li | 2018 | Cell Research2018，28，9： | 18 |
| 2 | Electronic Skin from High-Throughput Fabrication of Intrinsically Stretchable Lead Zirconate Titanate Elastomer显示文摘Electronic skin made of thin,soft,stretchable devices that can mimic the human skin and reconstruct the tactile sensation and perception offers great opportunities for prosthesis sensing,robotics controlling,and human-machine interfaces.Advanced materials and mechanics engineering of thin film devices has proven to be an efficient route to enable and enhance flexibility and stretchability of various electronic skins;however,the density of devices is still low owing to the limitation in existing fabrication techniques.Here,we report a high-throughput one-step process to fabricate large tactile sensing arrays with a sensor density of 25 sensors/cm^(2) for electronic skin,where the sensors are based on intrinsically stretchable piezoelectric lead zirconate titanate(PZT)elastomer.The PZT elastomer sensor arrays with great uniformity and passive-driven manner enable highresolution tactile sensing,simplify the data acquisition process,and lower the manufacturing cost.The high-throughput fabrication process provides a general platform for integrating intrinsically stretchable materials into large area,high device density soft electronics for the next-generation electronic skin. | Yiming Liu Huanxi Zheng Ling Zhao Shiyuan Liu Kuanming Yao Dengfeng Li Chunki Yiu Shenghan Gao Raudel Avila Pakpong Chirarattananon Lingqian Chang Zuankai Wang Xian Huang Zhaoqian Xie Zhengbao Yang Xinge Yu | 2020 | Research2020，，1： | 11 |
| 3 | Tree-Ring Latewood Width Based July–August SPEI Reconstruction in South China since 1888 and Its Possible Connection with ENSO显示文摘Our understanding of the long-term hydroclimate variations in South China is prohibited by the shortness of meteorological records. Paleoclimatic proxies, such as tree-rings, can be pursued to extend the meteorological records back for centuries to help us better understand hydroclimatic conditions. In this study, we reconstructed the July–August standardized precipitation–evapotranspiration index(SPEI_(Jul–Aug)) based on a newly developed 127-yr adjusted latewood width chronology from Tsuga longibracteata, South China. The chronology explained 40% of the actual SPEI_(Jul–Aug) variance in the period 1953–2014. The reconstructed SPEI_(Jul–Aug) can represent large-scale July–August SPEI variations over South China, including northern Guangxi, Hunan, and Guizhou provinces. From the perspective of the past 127 years, the extreme summer drought in 2013 was not unusual because more extreme drought events occurred in the first half of the 20th century. A significant 2.0–3.6-yr hydroclimatic cycle existed in the reconstruction, which indicated that the SPEI_(Jul–Aug) might be driven by El Ni?o–Southern Oscillation(ENSO). We further checked the time-dependency of the relationship between SPEI_(Jul–Aug) and ENSO and found that it was unstable. Their relationship was weak before the 1950s, became significant from the 1950s to early 1990s, and then dropped to be weak again and even out of phase since the early 1990s, which may be attributable to the significant westward extension of the western Pacific subtropical high. | Yesi ZHAO Jiangfeng SHI Shiyuan SHI Jian YU Huayu LU | 2017 | Journal of Meteorological Research2017，31，1： | 9 |
| 4 | The diffusive fluxes of inorganic nitrogen across the intertidal sediment-water interface of the Changjiang Estuary in China显示文摘Ammonium and nitrate concentrations were analyzed in near-bottom water and pore water collected from ten stations of the intertidal flat of the Changjiang Estuary during April, July, November and February. The magnitudes of the benthic exchange fluxes were determined on the basis of concentration gradients of ammonium and nitrate at the near-bottom water and interstitial water interface in combination with calculations of a modified Fick’s first law. Ammonium fluxes varied from-5.05 to 1.43 μg/(cm 2 ·d) and were greatly regulated by the production of ammonium in surface sediments, while nitrate fluxes ranged from-0.38 to 1.36 μg/(cm 2 ·d) and were dominated by nitrate concentrations in the tidal water. It was found that ammonium was mainly released from sediments into water columns at most of stations whereas nitrate was mostly diffused from overlying waters to intertidal sediments. In total, 823.75 t/a ammonium-N was passed from intertidal sediments to water while about 521.90 t/a nitrate-N was removed from overlying waters to intertidal sediments. This suggests that intertidal sediments had the significant influence on modulating inorganic nitrogen in the tidal water. | HOU Lijun LIU Min XU Shiyuan LU Jianjian OU Dongni YU Jie | 2006 | Acta Oceanologica Sinica2006，25，3： | 5 |
| 5 | An incremental genetic algorithm approach to muhiprocessor scheduling显示文摘 | Annie S Wu Han Yu Shiyuan Jin et aI | 2004 | IEEE Transactions on Parallel and Distributed Systems2004，15，9： | 1 |
| 6 | An Incremental Genetic AlgorithmApproach to Multiprocessor Scheduling显示文摘 | Wu A S Yu H Shiyuan J | 2004 | IEEE Transactions on Parallel and Distributed Systems2004，15，9： | 1 |
| 7 | Electrospun chitosan-graft-poly,(-caprolactone)/poly,(-caprolactone) cationic nanofibrous mats as potential scaffolds for skin tissue engineering显示文摘 | Honglin Chen Jin Huang Jiahui Yu Shiyuan Liu Ping Gu | | 0，，： | 1 |
| 8 | An Incremental Genetic Algorithm Approach to Multiprocessor Scheduling显示文摘 | Annie S W Yu Han Jin Shiyuan | 2004 | IEEE Transactions on Parallel and Distributed Systems2004，15，9： | 1 |
| 9 | Circular RNA SMARCA5 suppressed non-small cell lung cancer progression by regulating miR-670-5p/RBM24 axis显示文摘Circular RNAs(circRNAs)have good stability and long half-life in blood and other body fluid,and possess regulatory effects on various biological processes as miRNA/RNA-binding protein sponges,or by competing endogenous RNA,indicating their great potential as biomarkers or targets of cancer therapy.In this study,we mainly explored the role and mechanism of circular RNA SMARCA5(circsSMARCA5)in non-small cell lung cancer(NSCLC).Quantitative RT-PCR was applied to measure the expression levels of genes,and then,the relationships among circsSMARCA5,microRNA-670-5p(miR-670-5p),and RBM24 were further analyzed.Animal and cell experiments were performed to explore the functions of circsSMARCA5 in NSCLC cells.The results showed that circsSMARCA5 was expressed at low level in NSCLC tissues and cells,while miR-670-5p had high level in NSCLC tissues.Dual luciferase reporter assay verified that miR-670-5p was the target of circsSMARCA5,and RBM24 has the binding site of miR-670-5p.Further analysis showed that circsSMARCA5 could negatively regulate miR-670-5p and had positive relationship with RBM24.Moreover,circsSMARCA5 obviously inhibited tumor growth in vivo,reduced cell proliferation and increased cell apoptosis in vitro,while miR-670-5p mimic or RBM24 knockdown could reverse these effects.Thus,circsSMARCA5 may serve as an NSCLC suppressor by regulating the miR-670-5p/RBM24 axis,and it may have the potential to be a biomarker or therapeutic target for NSCLC. | Danjie Zhang Yuefeng Ma Zhenchuan Ma Shiyuan Liu Liangzhang Sun Jianzhong Li Feng Zhao Yu Li Jin Zhang Shaomin Li Jiantao Jiang | 2020 | Acta Biochimica et Biophysica Sinica2020，52，10： | 1 |
| 10 | Evaluation of the combined risk of sea level rise, land subsidence, and storm surges on the coastal areas of Shanghai, China显示文摘 | Jun Wang Wei Gao Shiyuan Xu Lizhong Yu | 2012 | Climatic Change2012，，3： | 1 |
| 11 | Tunable Atomic-Scale Steps and Cavities Break Both Stability and Activity Limits of CoO_(x) Nanosheets to Catalyze Oxygen Evolution显示文摘A highly active interface can enhance the catalytic efficiency of catalysts toward the oxygen evolution reaction(OER).However,accurately tuning their atomic interface configurations of defects with sufficient activity and stability remains a grand challenge.Herein,we report on breaking the activity and stability limits of CoO_(x) nanosheets in the OER process by constructing copious high-energy atomic steps and cavities,in which S or Ce atoms simultaneously replace O or Co atoms from CoO_(x),thus achieving high-energy atomic interface Ce,O-Co_(3)S_(4) nanosheets.By combining in situ characterization and density functional theory calculations,it is shown that the unique orbital coupling between Ce-4f,O(S)-2p,and Co-3d causes it to be closer to the Fermi level,leading to faster charge transfer capability.More importantly,the novel structure breaks the stability limit of cobalt sulfide with planar defects,which gives high catalytic activity and stability in 0.1 M KOH solutions,better than commercial RuO_(2) and IrO_(2) noble metal catalysts.As expected,Ce,O-Co_(3)S_(4) possesses much better turnover frequency activity(0.064 s^(-1))at an overpotential of 300 mV,which is ~7 times larger than that of Ce-CoO_(x)(0.009 s^(-1)).Our work presents a new perspective of designing catalysts with atomically dispersed orbital electronic coupling defects toward efficient OER electrocatalysis. | Min Yu Xueqin Mu Weitao Meng Ziyue Chen Yu Tong Yu Ge Shiyuan Pang Shengjie Li Suli Liu Shichun Mu | 2023 | Renewables2023，1，4： | 1 |
| 12 | Influence of superior cervical ganglionectomy on hippocampal neurogenesis and learning and memory in adult rats显示文摘BACKGROUND:Studies have shown that neurogenesis in the dentate gyrus plays an important role in learning and memory.However,studies have not determined whether the superior cervical ganglion or the sympathetic nerve system influences hippocampal neurogenesis or learning and memory in adult rats. OBJECTIVE:To observe differences in dentate gyrus neurogenesis,as well as learning and memory,in adult rats following superior cervical ganglionectomy. DESIGN,TIME AND SETTING:A randomized,controlled,animal study was performed at the Immunohistochemistry Laboratory of the School of Life Sciences in Lanzhou University from July 2006 to July 2007. MATERIALS:Doublecortin polyclonal antibody was provided by Santa Cruz Biotechnology,USA; avidin-biotin-peroxidase complex was purchased from Zhongshan Goldenbride Biotechnology, China;Morris water maze was bought from Taimeng Technology,China. METHODS:A total of 20 adult,male,Wistar rats were randomly divided into surgery and control groups,with 10 rats in each group.In the surgery group,the bilateral superior cervical ganglions were transected.In the control group,the superior cervical ganglions were only exposed,but no ganglionectomy was performed. MAIN OUTCOME MEASURES:To examine distribution,morphology,and number of newborn neurons in the dentate gyrus using doublecortin immunohistochemistry at 36 days following surgical procedures.To examine ability of learning and memory in adult rats using the Morris water maze at 30 days following surgical procedures. RESULTS:Doublecortin immunohistochemical results showed that a reduction in the number of doublecortin-positive neurons in the surgery group compared to the control group(P<0.05),while the distribution of doublecortin-positive neurons was identical in the two groups.The surgery group exhibited significantly worse performance in learning and spatial memory tasks compared to the control group(P<0.05). CONCLUSION:Superior cervical ganglionectomy inhibited neurogenesis in the dentate gyrus and decreased learning and memory abilities in adult rats. | Yanping Ding Baoping Shao Shiyuan Yu Shanting Zhao Jianlin Wang | 2009 | Neural Regeneration Research2009，4，9： | 1 |
| 13 | Study on the climate changes recorded in the sediment of the Caohu Lake during the last 300 years 显示文摘 | Fan Bin Xu Shiyuan Yu Lizhong | 2007 | Journal of East China Normal University( Nat- ural Scicence)2007，4，： | 1 |
| 14 | Transport and Magnetic Properties of Perovskite-Type Manganite (La_(0.8-x)Ce_x Sr_ (0.2))_ (0.97)MnO_3显示文摘[WT]Phase structures, the transport and magnetic properties of the Perovskite-type manganite (La 0.8-xCexSr 0.2) 0.97 MnO3 (x=0~0.26) prepared by La2O3 containing CeO2 with different contents were studied. Experiments show that the compounds consist of a magnetic perovskite phase and non-magnetic CeO2 and Mn3O4. The resistivity and magnetoresistance ratio (MR) of the samples vary with changing x. Their room-temperature MR reaches -3%~-14% at the magnetic field of 1 T. For x=0; x=0.037 and x=0.26 samples, the conductance keeps unchanged basically in a relatively wide temperature range above 600 K, and the result shows that it is feasible for producing SOFC cathode materials with these samples. | Yu Jiangying Zhang Shiyuan | 2005 | Journal of Rare Earths2005，23，5： | 1 |
| 15 | Risk SNP-induced lncRNA-SLCCl drives colorectal cancer through activating glycolysis signaling显示文摘Long non-coding RNAs(lncRNAs)play key roles in colorectal carcinogenesis.Here,we aimed to identify the risk SNP-induced lncRNAs and to investigate their roles in colorectal carcinogenesis.First,we identified rs6695584 as the causative SNP in 1 q41 locus.The A>G mutation of rs6695584 created a protein-binding motif of BATF,altered the enhancer activity,and subsequently activated IncSLCCl expression.Further validation in two independent CRC cohorts confirmed the upregulation of IncSLCCl in CRC tissues,and revealed that increased IncSLCCl expression was associated with poor survival in CRC patients.Mechanistically,lncRNA-SLCCl interacted with AHR and transcriptionally activated HK2 expression,the crucial enzyme in glucose metabolism,thereby driving the glycolysis pathway and accelerating CRC tumor growth.The functional assays revealed that IncSLCCl induced glycolysis activation and tumor growth in CRC mediated by HK2.In addition,HK2 was upregulated in colorectal cancer tissues and positively correlated with IncSLCCl expression and patient survival.Taken together,our findings reveal a risk SNP-mediated oncogene lncRNA-SLCCl promotes CRC through activating the glycolysis pathway. | Tingting Yan Chaoqin Shen Penglei Jiang Chenyang Yu Fangfang Guo Xianglong Tian Xiaoqiang Zhu Shiyuan Lu Bingshe Han Ming Zhong Jinxian Chen Qiang Liu Yingxuan Chen Junfang Zhang Jie Hong Haoyan Chen Jing-Yuan Fang | 2021 | Signal Transduction and Targeted Therapy2021，6，3： | 1 |
| 16 | An incremental genetic algorithm approach to multiprocessor scheduling 显示文摘 | Annie S Wu Han Yu Shiyuan Jin | 2004 | IEEE Trans on Parallel and Distributed Systems2004，15，9： | 1 |
| 17 | An Incremental Genetic Algorithm Approach to Multiprocessor Scheduling 显示文摘 | Wu A S Yu Han Jin Shiyuan | 2004 | IEEE Transaction on Parallel and Distributed Systems2004，15，9： | 1 |
| 18 | Mid-infrared hyperchaos of interband cascade lasers显示文摘Chaos in nonlinear dynamical systems is featured with irregular appearance and with high sensitivity to initial conditions.Near-infrared light chaos based on semiconductor lasers has been extensively studied and has enabled various applications.Here,we report a fully-developed hyperchaos in the mid-infrared regime,which is produced from interband cascade lasers subject to the external optical feedback.Lyapunov spectrum analysis demonstrates that the chaos exhibits three positive Lyapunov exponents.Particularly,the chaotic signal covers a broad frequency range up to the GHz level,which is two to three orders of magnitude broader than existed mid-infrared chaos solutions.The interband cascade lasers produce either periodic oscillations or low-frequency fluctuations before bifurcating to hyperchaos.This hyperchaos source is valuable for developing long-reach secure optical communication links and remote chaotic Lidar systems,taking advantage of the high-transmission windows of the atmosphere in the mid-infrared regime. | Yu Deng Zhuo-Fei Fan Bin-Bin Zhao Xing-Guang Wang Shiyuan Zhao Jiagui Wu Frédéric Grillot Cheng Wang | 2022 | Light(Science & Applications)2022，11，1： | 1 |
| 19 | Optimal economic dispatching of multi-microgrids by an improved genetic algorithm显示文摘A multi-microgrid economic dispatching strategy based on adaptive mutation genetic algorithm is proposed for multi-microgrid systems with different load types and power demands.Based on the analysis of industrial,residential and commercial loads,considering the synergy and complementarity between multi-microgrids,an optimal dispatching model of multi-microgrids based on the minimum operation cost and environmental protection cost of multi-microgrids is established from the point of view of environmental protection and economy.At the same time,an adaptive mutation genetic algorithm is proposed to optimize the system model and find the optimal economic dispatching scheme. | Haoyu Jiang Shiyuan Ning Quanbo Ge Wang Yun JinQiang Xu Yu Bin | 2021 | IET Cyber-Systems and Robotics2021，3，1： | 1 |
| 20 | An Incremental Genetic Algorithm Approach to Multiprocessor Scheduling显示文摘 | Wu A S Yu Han Jin Shiyuan | | 0，，09： | 1 |
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