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| 1 | Characterization and Apparent Kinetics of Polymerization of 1-Decene Catalyzed by Boron Trifluoride/Alcohol System显示文摘Poly-α-olefin(PAO) synthetic oil is the base oil of high-quality lubricants, and has a huge market potential.We illustrate PAO synthesis by catalytic polymerization of 1-decene with a boron trifluoride(BF_3)/alcohol system. Gas chromatography–mass spectrometry, proton nuclear magnetic resonance and ^(13) C nuclear magnetic resonance analysis confirmed dimer, trimer and tetramer structures of PAO. Each component contained branched chains with a 1,2 insertion of a head-to-tail link; a 2,1 insertion of a tail-to-tail link and a methyl-containing linked structure. At a low conversion rate, the reaction rate was related directly with the reaction temperature and the catalyst/1-decene concentration. An apparent kinetic equation for PAO formation was determined during 1-decene polymerization. | Wang Sihan Wang Libo Liu Tong Ma Lili Huo Hongliang Wang Jian | 2017 | China Petroleum Processing & Petrochemical Technology2017，19，3： | 7 |
| 2 | Global transcriptome analysis for identification of interactions between coding and noncoding RNAs during human erythroid differentiation显示文摘在 erythroid 开发期间编码基因, miRNAs,和 lncRNAs 上的研究在最近的年里被执行了。然而,集中于三种 RNA 类型的集成的分析还得被做。在现在的学习,我们比较了编码基因, miRNA,和 lncRNA 表示侧面的动力学。为了在在 transcriptome 控制这些变化的红血球生成和潜在的机制探索动态变化,铺平,我们利用了定序技术从绳索血获得 transcriptome 数据的高产量造血的干细胞和下列四个 erythroid 区别阶段,以及从成熟的红血房间。结果显示 lncRNAs 为 erythroid 区别正在答应房间标记候选人。聚类分析分类差别表示基因进在 stemness 维护期间对应于动态变化的四种子类型,中间区别,并且成熟。综合分析揭示了 RNA 潜在地参予了控制血细胞成熟的那 noncoding,并且特别与到氧种类和 DNA 损坏的 heme 新陈代谢和回答联系了。这些规章的相互作用在一个全面网络,在 RNA 之间的从而推断的关联和他们的联系功能被显示。这些数据为正常红血球生成的学习提供了一个大量的资源,它将允许 erythroid 开发的进一步的调查和理解并且获得 erythroid 混乱。 | Nan Ding Jiafei Xi Yanming Li Xiaoyan Xie Jian Shi Zhaojun Zhang Yanhua Li Fang Fang Sihan Wang Wen Yue Xuetao Pei Xiangdong Fang | 2016 | Frontiers of Medicine2016，10，3： | 6 |
| 3 | Identification and functional analyses of novel antioxidant peptides and antimicrobial peptides from skin secretions of four East Asian frog species显示文摘在现在的学习,我们识别了从 Amolops daiyunensis, Pelophylax hubeiensis, Hylarana maosuoensis 和 Nanorana pleskei 与抗氧化剂或抗菌剂活动被分类进 21 个肽家庭的 50 肽,它在 Ranidae 和 Dicroglossidae 家庭属于四个不同的类。这四青蛙种第一次被作出对有利的裁决表示抗氧化剂肽(AOP ) 和抗菌剂肽(安培) 。这些肽包括七最新发现的家庭 daiyunin-1, daiyunin-2, daiyunin-3, maosonensis-1MS1, pleskein-1, pleskein-2,和 pleskein-3。抗氧化剂和抗菌剂活动试金证明一些这些肽举办好生物活动。例如,在两个都展出的 50 M, nigroain-B-MS1,和 nigroain-C-MS1 的集中,相对强壮的 2,2-diphenyl-1-picrylhydrazyl (DPPH ) 和 2,2-azinobis-(3-ethylbenzothiazoline-6-sulfonicacid )(ABTS ) 释放激进的清除能力与 99.7% 和 68.3% 的根除率(nigroain-B-MS1 ) ,并且 99.8% 和 58.3%(nigroain-C-MS1 ) 分别地。这些肽是新奇抗氧化剂或安培准备的发展的潜在的候选人。 | Xiao Wang Shuguang Ren Chao Guo Weiqi Zhang Xiaoli zhang Baowen Zhang Sihan Li Jian Ren Yuhong Hu Hui Wang | 2017 | Acta Biochimica et Biophysica Sinica2017，49，6： | 3 |
| 4 | A Bionic Study on the Anti-erosion Mechanism of Laudakia stoliczkana:Experimental and Numerical Aspects显示文摘The scales of body surface of Laudakia stoliczkana have the morphology of convex hulls,which are arranged in groove structure in macroscopic scale.Its body surface skin is mainly composed of the'soft'layer of keratin and the'hard'layer of the cuticle covering on the'soft'layer.The coupling effect of the scale morphology and skin's structure gives Laudakia stoliczkana the excellent ability to resist the sand erosion in desert environment.Inspired by the convex surface morphology and the composite structure of the'soft'and'hard'layers of the skin of Laudakia stoliczkana^the coupling bionic samples are febricated and the erosion resistance performance is tested.The test results show that the coupling bionic samples have good erosion resistance perfbimance and the samples with spherical convex hull exhibit the best erosion resistance performance.Moreover,based on the theory of stress wave propagation in solid the numerical simula tions of particles impacting to the coupling bionic samples and bionic layered structure are done respectively and the anti-erosion me chanism of the bionic layered structure is analyzed.The simulation results are consistent with the experimental results,which show that the coupling bionic samples can effectively reduce the amplitude of the incident stress wave,and thus can prevent the failure of samples. | Ping Liang Youhong Sun Sihan Liu Tianwei Liang Yuhang Zhang Youwei Wang Luquan Ren | 2019 | Journal of Bionic Engineering2019，16，5： | 2 |
| 5 | One-dimensional iron oxides nanostructures显示文摘Iron oxides,including α-Fe2O3,γ-Fe2O3,Fe3O4,etc.are one of the most widely investigated materials for their fundamental properties and potential applications.One-dimensional(1-D) iron oxides nanostructures are the focus of recent research activities because of their wide applications in magnetic refrigeration,information storage,electronics,catalysts,Li-ion battery,pigment,gas sensors,etc.This review covers the recent progress in the synthesis,properties and applications of 1-D iron oxides nanostructures.The paper begins with the introduction to 1-D iron oxides nanostructures,followed by the typical synthetic methods developed for the synthesis of 1-D iron oxides nanostructures.Then,the typical 1-D iron oxides nanostructures,including nanowires/nanorods,nanotubes,nanobelts,nanochains,and special 3-D structures built on 1-D building blocks,are introduced in detail.The properties of 1-D iron oxides nanostructures are then discussed,focusing on the magnetic,gas sensing,and electrochemical and photocatalytic properties.Finally,we draw conclusions and look at the prospects of 1-D iron oxides nanostructures. | CHEN Di XIONG Shi RAN SiHan LIU Bin WANG LiMing SHEN GuoZhen | 2011 | Science China(Physics,Mechanics & Astronomy)2011，54，7： | 2 |
| 6 | CAPE promotes the expansion of human umbilical cord blood-derived hematopoietic stem and progenitor cells in vitro显示文摘Due to the low number of collectable stem cells from single umbilical cord blood(UCB)unit,their initial uses were limited to pediatric therapies.Clinical applications of UCB hematopoietic stem and progenitor cells(HSPCs)would become feasible if there were a culture method that can effectively expand HSPCs while maintaining their self-renewal capacity.In recent years,numerous attempts have been made to expand human UCB HSPCs in vitro.In this study,we report that caffeic acid phenethyl ester(CAPE),a small molecule from honeybee extract,can promote in vitro expansion of HSPCs.Treatment with CAPE increased the percentage of HSPCs in cultured mononuclear cells.Importantly,culture of CD34+HSPCs with CAPE resulted in a significant increase in total colony-forming units and high proliferative potential colony-forming units.Burst-forming unit-erythroid was the mostly affected colony type,which increased more than 3.7-fold in 1μg mL 1CAPE treatment group when compared to the controls.CAPE appears to induce HSPC expansion by upregulating the expression of SCF and HIF1-α.Our data suggest that CAPE may become a potent medium supplement for in vitro HSPC expansion. | LIU YiMing ZHANG BoWen ZHANG Jing WANG SiHan YAO HaiLei HE LiJuan CHEN Lin YUE Wen LI YanHua PEI XueTao | 2014 | Science China(Life Sciences)2014，57，2： | 2 |
| 7 | Thermal Behavior Analysis of Stacked-type Supercapacitors with Different Cell Structures显示文摘As a new energy storage element,supercapacitors have characteristics such as high power density,fast charge and discharge rates,green environmental protection,and long cycle life.Temperature is an important parameter of supercapacitors which significantly influences the stability of the supercapacitors.In this study,the finite element method is used to realize a coupling between a one-dimensional electrochemical model and a three-dimensional thermal model.Then,based on this model,the concept of limited cycle numbers is defined,and different unit quantities,unit size,and the effect of temperature under different temperature environments such as low temperature,room temperature,and high temperature on stacked-type supercapacitors is studied.Finally,stacked-type supercapacitors are compared with rolled-type supercapacitors considering the same cell size,density,and volume approximations.The simulation results show that the higher the number of packaging units,the lower is the limit cycle number.This phenomenon is more pronounced under high current than under low current conditions.Increasing the package size of the porous electrode or separator decreases the limiting cycles.Under the same unit volume scenario,improving the separator size proportion can accurately control the temperature rise at small current values.Under the same material,volume,and density approximations,the temperature rises slowly for stacked-type supercapacitors as compared to rolled-type supercapacitors.This phenomenon is more pronounced with an increase in current. | Yansong Li Sihan Wang Meina Zheng Jun Liu | 2018 | CSEE Journal of Power and Energy Systems2018，4，1： | 2 |
| 8 | A shedding soluble form of interleukin-17 receptor D exacerbates collagen-induced arthritis through facilitating TNF-α-dependent receptor clustering显示文摘Rheumatoid arthritis(RA)is exacerbated by TNF-alpha signaling.However,it remains unclear whether TNF-α-activated TNFR1 and TNFR2 are regulated by extracellular factors.Here,we showed that soluble glycosylated interleukin-17 receptor D(sIL-17RD),which was produced by proteolytic cleavage,enhanced TNF-α-induced RA.We revealed that IL-17RD shedding was induced by the proteolytic enzyme TACE and enhanced by TNF-αexpression in macrophages.Intriguingly,sIL-17RD was elevated in the sera of arthritic mice and rats.Recombinant sIL-17RD significantly enhanced the TNF-α-induced proinflammatory response by promoting TNF-α-TNFR-sIL-17RD complex formation and receptor clustering,leading to the accelerated development of collagen-induced arthritis.Our observations revealed that ectodomain shedding of IL-17RD occurred in RA to boost the TNF-α-induced inflammatory response.Targeting sIL-17RD may provide a new strategy for the therapy of RA. | Sihan Liu Yanxia Fu Kunrong Mei Yinan Jiang Xiaojun Sun Yinyin Wang Fangli Ren Congshan Jiang Liesu Meng Shemin Lu Zhihai Qin Chen Dong Xinquan Wang Zhijie Chang Shigao Yang | 2021 | Cellular & Molecular Immunology2021，18，8： | 1 |
| 9 | Active phase of highly active C% 04 catalyst for synthetic natural gas production显示文摘 | Wang Baowei Liu Sihan Hu Zongyuan | 2014 | RSC Adv2014，4，57： | 1 |
| 10 | Preparation of antifouling ultrafiltration membranes from copolymers of polysulfone and zwitterionic poly(arylene ether sulfone)s显示文摘The past few decades have witnessed rapid gains in our demands of antifouling membranes such as water purification membranes and hemodialysis membranes.A variety of methodologies have been proposed for improving the antifouling performance and the hemocompatibility of the membranes.In this study,a series of copolymers(PSF-PESSB)containing polysulfone(PSF)and poly(arylene ether sulfone)bearing pendant zwitterionic sulfobetaine groups(PESSB)were prepared via one-pot polycondensation.Subsequently,the ultrafiltration(UF)membranes were prepared from different zwitterion-containing copolymers.The prepared membranes showed high thermal stability and mechanical properties.Besides,it also displayed attractive antifouling performance and blood compatibility.Compared with the original PSF membrane,the amount of protein absorption on the modified membrane was reduced;the flux recovery ratio and the resistance to blood cells were significantly improved.The results of this work suggest that PSF-PESSB membranes are expected to be applied in blood purification.The introduction of zwitterion-containing polymers to membranes paves ways for developing advanced hemodialysis technologies for crucial process. | Sihan Huang Yaohan Chen Xue Wang Jing Guo Yonggang Li Lei Dai Shenghai Li Suobo Zhang | 2022 | Chinese Journal of Chemical Engineering2022，35，9： | 1 |
| 11 | Development and antiftmgal evaluation of a food-grade U-type microemulsion显示文摘 | ZHANG Hui LU Zhonghua WANG Sihan | 2008 | Journal of Applied Microbiology2008，105，4： | 1 |
| 12 | Plasma miR-126 Is a Potential Biomarker for Early Prediction of Type 2 Diabetes Mellitus in Susceptible Individuals显示文摘 | Tao Zhang Chunfang Lv Liling Li Sihan Chen Shenglin Liu Changyi Wang Bing Su Thean Hock Tang | 2013 | BioMed Research International2013，，： | 1 |
| 13 | Honeycomb-Like Hydrogel Microspheres for 3D Bulk Construction of Tumor Models显示文摘A two-dimensional(2D)cell culture-based model is widely applied to study tumorigenic mechanisms and drug screening.However,it cannot authentically simulate the threedimensional(3D)microenvironment of solid tumors and provide reliable and predictable data in response to in vivo,thus leading to the research ilusionis and failure of drug screening.In this study,honeycomb-like gelatin methacryloyl(GelMA)hydrogel microspheres are developed by synchronous photocrosslinking microluidic technique to construct a 3D model of osteosarcoma.The in vitro study shows that ostcosarcoma cells(K7M2)culured in 3D GelMA microspheres have stronger tumorous stemness。proliferation and migration abilitics,more osteoclastogenetic ability,and reistance to chemotherapeutic drugs(DOX)than that of cells in 2D cultures.More imporantly,the 3D-cultured K7M2 cells show more tumorigenicity in immunologically sound mice,characterized by shorter tumorigenesis time,larger tumor volumc,severe bone destruction,and higher mortality.In conclusion,honeycomb like porous microsphere scaffolds are constructed with uniform structure by micofluidic technology to massively produce tumor cells with original phenotypes.Those microspheres could recapitulate the physiology microenvironment of tumors.maintain ell-cell and cell-extracellular matrix interactions,and thus provide an efective and convenient strategy for tumor pathogenesis and drug screening research. | Jiachen He Chichi Chen Liang Chen Ruoyu Cheng Jie Sun Xingzhi Liu Lin Wang Can Zhu Sihan Hu Yuan Xue Jian Lu Huiling Yang Wenguo Cui Qin Shi | 2022 | Research2022，，2： | 1 |
| 14 | Multimaterial additive manufacturing manipulator for fabricating magnetoelectric pressure sensors显示文摘The simultaneous placement of different types of materials including polymers,ceramics,and metals,in their desired positions could be adopted to manufacture end-use devices/apparatuses with diverse functionalities and significantly reduce the fabrication cost and time.However,existing additive manufacturing(AM)approaches can only treat one material species at a time due to their intrinsic working mechanisms.Here we develop an AM manipulator for manufacturing a wide variety of material species,including polymers,ceramics,and metals,through a multifilament transport strategy assisted by laser power.The six-jaw manipulator contains three pairs of filament delivering/cutting systems for transporting diverse materials and a beam of tunable laser as the thermal source.The whole apparatus is integrated into a robotic manipulator to create a multifreedom manufacturing platform.With this innovation,products with multiple material species and desired complex geometries can be fabricated on demand.Furthermore,we synthesize a multimaterial(polymer/ceramic/metal)printed magnetoelectric pressure sensor that can convert applied mechanical forces to electricity and maintain efficiency even after undergoing 10000 cycles of pressure/recovery.With this multimaterial filament transport and laser manufacturing strategy,our AM manipulator exhibits promising application in the advanced manufacturing of embedded electronics,sensors,soft robotics,and customizable medical devices. | LIU ZhuFeng LI ZhaoQing WANG Qi WANG Yan YANG Lei NIE Xiang GENG Peng WU ZhenHua TANG SiHan YANG Lei WU HongZhi SHI YunSong CHEN Peng SU Bin ZHANG LiChao YAN ChunZe SHI YuSheng | 2022 | Science China(Technological Sciences)2022，65，11： | 1 |
| 15 | cAMP-PGC1α途径诱导的抗Warburg效应驱动胶质母细胞瘤细胞分化为星形胶质细胞显示文摘文章简介多形性胶质母细胞瘤(GBM)是人类最具侵袭性的肿瘤之一。虽然分化治疗已被提出作为治疗GBM的潜在方法,但诱导分化的机制仍然很不清楚。在此,课题组利用c AMP激活剂建立了GBM诱导分化模型,该模型特异性地指导GBM分化为星形胶质细胞。 | Fan Xing Yizhao Luan Jing Cai Sihan Wu Jialuo Mai Jiayu Gu Haipeng Zhang Kai Li Yuan Lin Xiao Xiao Jiankai Liang Yuan Li Wenli Chen Yaqian Tan Longxiang Sheng Bingzheng Lu Wanjun Lu Mingshi Gao Pengxin Qiu Xingwen Su Wei Yin Jun Hu Zhongping Chen Ke Sai Jing Wang Furong Chen Yinsheng Chen Shida Zhu Dongbing Liu Shiyuan Cheng 谢志 朱文博 颜光美 | 2018 | 科学新闻2018，0，4： | 1 |
| 16 | A new facile approach to N-alkylpyrroles from direct redox reaction of 4-hydroxy-L-proline with aldehydes显示文摘An unprecedented acetic acid-catalyzed efficient access to N-alkylpyrroles from reaction of 4-hydroxy-L-proline with a variety of aldehydes has been achieved in good to excellent yields under mild reaction conditions. | ZOU ZhiQin DENG ZeJun YU XinHong ZHANG ManMan ZHAO SiHan LUO Ting YIN Xin XU Hui WANG Wei | 2012 | 中国科学:化学2012，42，2： | 0 |
| 17 | Genetic variants associated with pathological changes in Alzheimer's diseases显示文摘Alzheimer's disease(AD)is the most prevalent dementia partially driven by genetics.Recently,a meta-analysis of large scale genome-wide association studies has identified a quantity of AD risk genes.To further investigate the correlation between the genetic variants and pathological progress,we examined 94 brain samples in the Chinese population from the National Human Brain Bank for Development and Function. | Wang Yuanzhuo Hu Xinzhi Liu Fan Sihan Liu Chen Chao Ma Chao | 2021 | 解剖学杂志2021，44，S01： | 0 |
| 18 | Transformer fault diagnosis based on relational teacher-student network显示文摘The analysis of dissolved gas in oil can provide an important basis for transformer fault diagnosis.In order to improve the accuracy of transformer fault diagnosis,a method based on the relational teacher-student network(R-TSN)is proposed by analyzing the relationship between the dissolved gas in the oil and the fault type.R-TSN replaces the original hard labels with soft labels,and uses it to measure the similarity between different samples in the space,to a certain extent,it can obtain the hidden feature information in the samples,and clarify the classification boundary.Through the identification experiment,the effect of R-TSN diagnosis model is analyzed,and the influence of the compound fault of discharge and thermal on the diagnosis model is studied.This paper compares R-TSN with support vector machines(SVMs),decision trees and multilayer perceptron models in transformer fault diagnosis.Experimental results show that R-TSN has better performance than the above methods.After adding compound faults in the sample set,the accuracy rate can still reach 86.0%. | Yin Sihan Li Yalei Liu Xiaoping Cui Xu Wang Huapeng | 2023 | The Journal of China Universities of Posts and Telecommunications2023，30，3： | 0 |
| 19 | A novel biodegradable high nitrogen iron alloy with simultaneous enhancement of corrosion rate and local corrosion resistance显示文摘To improve the corrosion rate and suppress the local corrosion,a novel biodegradable high nitrogen(N)FeMnN alloy was developed,and the effects of N content on the corrosion behaviors were systematically investigated.It was found that,as the N content increased,the corrosion rate was significantly enhanced in both Hank’s solution and simulated gastric fluid.Meanwhile,as the N content increased,the size and depth of pits decreased obviously,and the number of pits increased,which presented a more uniform corrosion morphology.X-ray photoelectron spectroscopy(XPS)results indicated that N existed in the form of NH_(4)^(+) in the corrosion products and[FeN]clusters in the matrix.The[FeN]clusters would simultane-ously improve the corrosion rate and suppress the local corrosion,which provides a new perspective for the development of biodegradable Fe alloy. | Sihan Lu Qingchuan Wang Yi Zhang Huabing Li Hao Feng Lili Tan Ke Yang | 2023 | Journal of Materials Science & Technology2023，，21： | 0 |
| 20 | Control of lupus activity during pregnancy via the engagement of IgG sialylation:novel crosstalk between IgG sialylation and pDC functions显示文摘Immunoglobulin(IgG)glycosylation affects the effector functions of IgG in a myriad of biological processes and has been closely associated with numerous autoimmune diseases,including systemic lupus erythematosus(SLE),thus underlining the pathogenic role of glycosylation aberration in autoimmunity.This study aims to explore the relationship between IgG sialylation patterns and lupus pregnancy.Relative to that in serum samples from the control cohort,IgG sialylation level was aberrantly downregulated in serum samples from the SLE cohort at four stages(from preconception to the third trimester of pregnancy)and was significantly associated with lupus activity and fetal loss during lupus pregnancy.The type I interferon signature of pregnant patients with SLE was negatively correlated with the level of IgG sialylation.The lack of sialylation dampened the ability of IgG to suppress the functions of plasmacytoid dendritic cells(pDCs).RNA-seq analysis further revealed that the expression of genes associated with the spleen tyrosine kinase(SYK)signaling pathway significantly differed between IgG-and deSia-IgG-treated pDCs.This finding was confirmed by the attenuation of the ability to phosphorylate SYK and BLNK in deSia-IgG.Finally,the coculture of pDCs isolated from pregnant patients with SLE with IgG/deSia-IgG demonstrated the sialylation-dependent anti-inflammatory function of IgG.Our findings suggested that IgG influences lupus activity through regulating pDCs function via the modulation of the SYK pathway in a sialic acid-dependent manner. | You Wang Sihan Lin Jiayue Wu Meng Jiang Jianhua Lin Yu Zhang Huihua Ding Haibo Zhou Nan Shen Wen Di | 2023 | Frontiers of Medicine2023，17，3： | 0 |
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