|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Hepatitis C virus in human B lymphocytes transformed by Epstein-Barr virus in vitro by in situ reverse transcriptase-polymerase chain reaction显示文摘AIM To study persistence and replication ofheltitis C virus (HCV) in patients' peripheralblood mononuclear cells (PBMC) cultured invitro.METHODS Epstein-Barr virus (EBV) was usedto transform the hepatitis C virus from a HCVpositive patient to permanent lymphoblastoidcell lines (LCL). Positive and negative HCV RNAstrands of the cultured cells and growth mediawere detected by reverse transcriptase-polymerase chain reaction ( RT-PCR ) eachmonth. Core and NS5 proteins of HCV werefurther tested using immunohistochemical SPmethod and in situ RT-PCR.RESULTS HCV RNA positive strands wereconsistently detected the cultured cells for oneyear. The negative-strand RNA in LCL cells andthe positive-strand RNA in supernatants wereobserved intermittently. Immunohistochemicalresults medicated expression of HCV NS3 and Cproteins in LCL cytoplasm mostly. The positivesignal of PCR product was dark blue and mainlylocalized to the LCL cytoplasm. The RT-PCRsignal was eliminated by overnight RNasedigestion but not DNase digestion.CONCLUSION HCV may exist and remainfunctional in a cultured cell line for a longperiod. | Ji Lin Cheng Bao Ling Liu Yi Zhang Wen Bin Tong Zheng Yan Bai Fang Feng Institute of Hepatology,Peoples Hospital,Medical Center of Beijing University,Beijing 10(X)44,China | 2001 | World Journal of Gastroenterology2001，7，3： | 11 |
| 2 | Interleukin-10 gene polymorphisms and hepatocellular carcinoma susceptibility:A meta-analysis显示文摘AIM: To assess the association between Interleu-kin-10 (IL-10) gene IL-10-1082 (G/A), IL-10-592(C/A), IL-10-819 (T/C) polymorphisms and hepatocellular carcinoma (HCC) susceptibility.METHODS: Two investigators independently searched the Medline, Embase, China National Knowledge Infrastructure, and Chinese Biomedicine Database. Summary odds ratios (ORs) and 95% conf idence intervals (95% CIs) for IL-10 polymorphisms and HCC were cal-culated in a fixed-effects model (the Mantel-Haenszel method) and a random-effects model (the DerSimonian and Laird method) when appropriate. RESULTS: This meta analysis included seven eligiblestudies, which included 1012 HCC cases and 2308 controls. Overall, IL-10-1082 G/A polymorphism was not associated with the risk of HCC (AA vs AG + GG, OR = 1.11, 95% CI = 0.90-1.37). When stratifying for ethnicity, the results were similar (Asian, OR = 1.12, 95% CI = 0.87-1.44; non-Asian, OR = 1.10, 95% CI = 0.75-1.60). In the overall analysis, the IL-10 polymorphism at position -592 (C/A) was identified as a genetic risk factor for HCC among Asians; patients carrying the IL-10-592*C allele had an increased risk of HCC (OR = 1.29, 95% CI = 1.12-1.49). No association was observed between the IL-10-819 T/C polymorphism and HCC susceptibility (TT vs TC + CC, OR = 1.02, 95% CI = 0.79-1.32).CONCLUSION: This meta-analysis suggests that IL-10-592 A/C polymorphism may be associated with HCC among Asians. IL-10-1082 G/A and IL-10-819 T/C polymorphisms were not detected to be related to the risk for HCC. | Yong-Gang Wei, Fei Liu, Bo Li, Xi Chen, Yu Ma, Lv-Nan Yan, Tian-Fu Wen, Ming-Qing Xu, Wen-Tao Wang, Jia-Yin YangYong-Gang Wei, Fei Liu, Bo Li, Xi Chen, Yu Ma, Lv-Nan Yan, Tian-Fu Wen, Ming-Qing Xu, Wen-Tao Wang, Jia-Yin Yang, Department of Liver and Vascular Surgery, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Prov- ince, China Author contributions: Wei YG and Liu F designed the study, collected and analyzed the data and wrote the manuscript Li B collected and analyzed the data and wrote the manuscript Chen X and Ma Y collected and analyzed the data Yan LN analyzed the data and contributed to the discussion Wen TF and Xu MQ revised the manuscript Wang WT and Yang JY contributed to the discussion Wei YG and Liu F contributed equally to this work. | 2011 | World Journal of Gastroenterology2011，17，34： | 3 |
| 3 | Overview to the Hard X-ray Modulation Telescope (Insight-HXMT) Satellite显示文摘As China’s first X-ray astronomical satellite, the Hard X-ray Modulation Telescope (HXMT), which was dubbed as Insight-HXMT after the launch on June 15, 2017, is a wide-band(1-250 ke V) slat-collimator-based X-ray astronomy satellite with the capability of all-sky monitoring in 0.2-3 Me V. It was designed to perform pointing, scanning and gamma-ray burst(GRB)observations and, based on the Direct Demodulation Method (DDM), the image of the scanned sky region can be reconstructed.Here we give an overview of the mission and its progresses, including payload, core sciences, ground calibration/facility, ground segment, data archive, software, in-orbit performance, calibration, background model, observations and some preliminary results. | Shuang-Nan Zhang TiPei Li FangJun Lu LiMing Song YuPeng X u CongZhan Liu Yong Chen XueLei Cao QingCui Bu Zhi Chang Gang Chen Li Chen TianXiang Chen YiBao Chen YuPeng Chen Wei Cui WeiWei Cui JingKang Deng YongWei Dong Yuan Yuan Du MinXue Fu GuanHua Gao He Gao Min Gao MingYu Ge YuDong Gu Ju Guan Can Gungor ChengCheng Guo DaWei Han Wei Hu Yue Huang Jia Huo ShuMei Jia LuHua Jiang WeiChun Jiang Jing Jin YongJie Jin Bing Li ChengKui Li Gang Li MaoShun Li Wei Li Xian Li XiaoBo Li XuFang Li YanGuo Li ZiJian Li ZhengWei Li XiaoHua Liang JinYuan Liao GuoQing Liu HongWei Liu ShaoZhen Liu XiaoJing Liu Yuan Liu YiNong Liu Bo Lu XueFeng Lu Tao Luo Xiang Ma Bin Meng Yi Nang JianYin Nie Ge Ou JinLu Qu Na Sai RenCheng Shang GuoHong Shen Liang Sun Ying Tan Lian Tao YouLi Tuo Chen Wang ChunQin Wang GuoFeng Wang HuanYu Wang Juan Wang WenShuai Wang YuSa Wang XiangYang Wen BaiYang Wu BoBing Wu Mei Wu GuangCheng Xiao ShaoLin Xiong LinLi Yan JiaWei Yang Sheng Yang YanJi Yang QiBin Yi Bin Yuan AiMei Zhang ChunLei Zhang ChengMo Zhang Fan Zhang HongMei Zhang Juan Zhang Qiang Zhang ShenYi Zhangs Shu Zhang Tong Zhang WanChang Zhang Wei Zhang WenZhao Zhang Yi Zhang YiFei Zhang YongJie Zhang Yue Zhang Zhao Zhang Zhi Zhang ZiLiang Zhang HaiSheng Zhao XiaoFan Zhao ShiJie Zheng JianFeng Zhou YuXuan Zhu Yue Zhu RenLin Zhuang | 2020 | Science China(Physics,Mechanics & Astronomy)2020，63，4： | 2 |
| 4 | 中国、日本、英国和美国24h膳食回顾法和24h尿钠法评估钠摄入的一致性显示文摘目前评估钠摄入有多种方法,其中包括膳食调查方法和尿钠的测定。24h尿钠法被认为是评估钠摄入的“金标准”,但是该方法在大样本研究中实施难度较大。所以,在很多大型研究中主要采用膳食调查方法。该研究分别在群体和个体水平上比较24h膳食回顾法和24h尿钠法评估钠摄入的差异。 | Wen X Zhou L Stamler J 张继国(编译) 黄绯绯(编译) | 2019 | 中华预防医学杂志2019，53，5： | 2 |
| 5 | Relationship between water chemistry and the distribution of the endangered aquatic quillwort Isotes sinensis Palmer in China显示文摘 | Wen M Z Pang X A Wang Q F | 2003 | Journal of Freshwater Ecology2003，18，3： | 1 |
| 6 | High performance calcium titanate nanoparticle ER fluids显示文摘 | Wang X Z Shen R Wen W J | 2005 | Int J Mod Phys B2005，19，79： | 1 |
| 7 | Optimization of polysaeeharides(ABP)extraction from the fruiting bodies of Agarieusblazei Mmillusing response surfae methodology显示文摘 | Liu J C Shu M Wen X C | 2009 | Carbohydrate Polymers2009，78，2： | 1 |
| 8 | Effect of pore structure on Ni catalyst for CO2 reforming of CH4显示文摘 | SUN N WEN X WANG F WEI W SUN Y | 2010 | Energy Environ Sci2010，3，3： | 1 |
| 9 | Assessment of immunoreactive synthetic peptides from the structural protein of severe acute respiratory syndrome coronavirus 显示文摘 | Wang J Q Wen J Li J X | 2003 | Clin Chem2003，49，： | 1 |
| 10 | Preconcentration of trace elements in sea water with poly (acrylaminophosphonic dithiocarbamate)chelating fiber for their determination by inductively coupled plasma mass spectrometry显示文摘 | WEN B SHAN X Q RUI-XIA LIU | 1999 | Journal of Analytical Chemistry1999，363，3： | 1 |
| 11 | TH2Cytokine-enhanced and TGF-beta-enhanced vascular endothelial growth factor production by cultured human airway smooth muscle cells is attenuated by IFNgamma and corticosteroids显示文摘 | Wen F Q Liu X Manda W | 2003 | J Allergy Clin Immunol2003，111，6： | 1 |
| 12 | Indoor and outdoor carbonyl compounds in the hotel ballrooms in Guangzhou,China显示文摘 | Feng Y Wen S Wang X | 2004 | Atmospheric Environment2004，38，： | 1 |
| 13 | Conjectural variation based bidding strategy in spot markets: fundamentals and comparison with classical game theoretical bidding strategies显示文摘 | Song Y Q Ni Y X Wen F S | 2003 | Electric Power Systems Research2003，67，1： | 1 |
| 14 | Continuous measurement of water vapor 180/160 and 2H/IH isotope ratios in the atmosphere显示文摘 | Wen X F Sun X M Zhang S C | 2008 | Journal of Hydrology2008，349，34： | 1 |
| 15 | Changes in serum adiponectin con- centrations and endothelial function after intensive insulin treat- ment in people with newly diagnosed type 2 diabetes: A pilot study显示文摘 | Li F Zhao T Y Wen X R | 2011 | Original Research Article Diabetes Research and Clini-cal Practice2011，94，2： | 1 |
| 16 | A critical study on the adsorption of heterocyclic sulfur and nitrogen compounds by activated carbon: Equilibrium, kinetics and thermodynamics显示文摘 | WEN J HAN X LIN H F ZHENG Y CHU W | 2010 | Chem Eng J2010，164，1： | 1 |
| 17 | Essential fatty acid requirement of the Chinese prawn, Penaeus chinensis 显示文摘 | XU X WEN J J CASTE L L | 1994 | Aquaculture1994，127，1： | 1 |
| 18 | Anterior versus posterior surgery for multilevel cervical myelopathy, which one is better? A systematic review显示文摘 | Tao L Wen X Tao C | 2011 | Eur Spine J2011，20，2： | 1 |
| 19 | Stability of titania nanoparticles in soil suspensions and transport in saturated homogeneous soil columns显示文摘 | Fang J Shan X Q Wen B | 2009 | Environmental Pollution2009，157，： | 1 |
| 20 | Assembly of TiO2-onCu2O nanocubes with narrow-band Cu2O-induced visiblelight-enhanced photocatalytic activity显示文摘 | LIU J L WEN M CHEN H X | 2014 | Chem Plus Chem2014，79，2： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员