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| 1 | Erianin,a novel dibenzyl compound in Dendrobium extract,inhibits lung cancer cell growth and migration via calcium/calmodulin-dependent ferroptosis显示文摘Ferroptosis,a novel form of programmed cell death,is characterized by iron-dependent lipid peroxidation and has been shown to be involved in multiple diseases,including cancer.Stimulating ferroptosis in cancer cells may be a potential strategy for cancer therapy.Therefore,ferroptosis-inducing drugs are attracting more attention for cancer treatment.Here,we showed that erianin,a natural product isolated from Dendrobium chrysotoxum Lindl,exerted its anticancer activity by inducing cell death and inhibiting cell migration in lung cancer cells.Subsequently,we demonstrated for the first time that erianin induced ferroptotic cell death in lung cancer cells,which was accompanied by ROS accumulation,lipid peroxidation,and GSH depletion.The ferroptosis inhibitors Fer-1 and Lip-1 but not Z-VAD-FMK,CQ,or necrostatin-1 rescued erianin-induced cell death,indicating that ferroptosis contributed to erianin-induced cell death.Furthermore,we demonstrated that Ca^(2+)/CaM signaling was a critical mediator of erianin-induced ferroptosis and that blockade of this signaling significantly rescued cell death induced by erianin treatment by suppressing ferroptosis.Taken together,our data suggest that the natural product erianin exerts its anticancer effects by inducing Ca^(2+)/CaMdependent ferroptosis and inhibiting cell migration,and erianin will hopefully serve as a prospective compound for lung cancer treatment. | Peng Chen Qibiao Wu Jiao Feng Lili Yan Yitian Sun Shuiping Liu Yu Xiang Mingming Zhang Ting Pan Xiaying Chen Ting Duan Lijuan Zhai Bingtao Zhai Wengang Wang Ruonan Zhang Bi Chen Xuemeng Han Yicong Li Liuxi Chen Ying Liu Xingxing Huang Ting Jin Wenzheng Zhang Hong Luo Xiaohui Chen Yongqiang Li Qiujie Li Guohua Li Qin Zhang Lvjia Zhuo Zuyi Yang Huifen Tang Tian Xie Xiaoping Ouyang Xinbing Sui | 2020 | Signal Transduction and Targeted Therapy2020，5，1： | 42 |
| 2 | Distribution and geological significance of 17α(H)-diahopanes from different hydrocarbon source rocks of Yanchang Formation in Ordos Basin显示文摘Based on GC-MS testing data of many saturated hydrocarbon samples, 17α(H)-C30 diahopanes (C30*) are extensively distributed in the lacustrine hydrocarbon source rocks of the Yanchang Formation in Ordos Basin, but show remarkable differences in relative abundance among various source rocks. Generally, Chang 7 high-quality source rock (oil shale) developed in deep lake anoxic environment shows lower C30* content, whereas Chang 6-9 dark mudstone developed in shallow to semi-deep lake, sub-oxidizing environment shows relatively high to high C30* value. Particularly, Chang 7 and Chang 9 black mudstones in Zhidan region in the northeast of the lake basin show extremely high C30* value. A comparative analysis was made based on lithology, organic types and various geochemical parameters indicative of redox environment, and the results indicate that environmental factors such as redox settings and lithology are key factors that control the C30* relative abundance, while organic types and maturity may be minor factors. High to extremely high C30* values are indicative of sub-oxidizing environment of fresh-brackish water and shallow to semi-deep lake. Therefore, research on C30* relative content and distribution in lacustrine hydrocarbon source rocks in the Yanchang Formation, especially on the difference in C30* between Chang 7 high-quality source rocks (oil shale) and Chang 6-91 source rocks (dark mudstone), will provide an important approach for classification of Mesozoic lacustrine crudes and detailed oil-source correlation in the basin. | ZHANG WenZheng YANG Hua HOU LiHui LIU Fei | 2009 | Science China Earth Sciences2009，52，7： | 16 |
| 3 | Epigenetics of epithelial Na^+ channel-dependent sodium uptake and blood pressure regulation显示文摘The epithelial Na+ channel(ENa C) consists of α,β,γsubunits.Its expression and function are regulated by aldosterone at multiple levels including transcription.ENa C plays a key role in Na+ homeostasis and blood pressure.Mutations in ENa C subunit genes result in hypertension or hypotension,depending on the nature of the mutations.Transcription of αENa C is considered as the rate-limiting step in the formation of functional ENa C.As an aldosterone target gene,αENa C is activated upon aldosterone-mineralocorticoid receptor binding to the cis-elements in the αENa C promoter,which is packed into chromatin.However,how aldosterone alters chromatin structure to induce changes in transcription is poorly understood.Studies by others and us suggest that Dot1a-Af9 complex represses αENa C by directly binding and regulating targeted histone H3 K79 hypermethylation at the specific subregions of αENa C promoter.Aldosterone decreases Dot1a-Af9 formation by impairing expression of Dot1 a and Af9 and by inducing Sgk1,which,in turn,phosphorylates Af9 at S435 to weaken Dot1a-Af9 interaction.MR attenuates Dot1aAf9 effect by competing with Dot1 a for binding Af9.Af17 relieves repression by interfering with Dot1a-Af9 interaction and promoting Dot1 a nuclear export.Af17-/-mice exhibit defects in ENa C expression,renal Na+ retention,and blood pressure control.This review gives a brief summary of these novel findings. | Wenzheng Zhang | 2015 | World Journal of Nephrology2015，4，3： | 7 |
| 4 | Geochemical characteristics and origin of gases from the Upper,Lower Paleozoic and the Mesozoic reservoirs in the Ordos Basin,China显示文摘The Ordos Basin,the second largest sedimentary basin in China,contains the broad distribution of natural gas types.So far,several giant gas fields have been discovered in the Upper and Lower Paleozoic in this basin,each having over 1000×10 8 m 3 of proven gas reserves,and several gas pools have also been discovered in the Mesozoic.This paper collected the data of natural gases and elucidated the geochemical characteristics of gases from different reservoirs,and then discussed their origin.For hydrocarbons preserved in the Upper Paleozoic,the elevatedδ13C values of methane,ethane and propane indicate that the gases would be mainly coal-formed gases;the singular reversal in the stable carbon isotopes of gaseous alkanes suggests the mixed gases from humic sources with different maturity.In the Lower Paleozoic,theδ13C 1 values are mostly similar with those in the Upper Paleozoic,but theδ13C 2 andδ13C 3 values are slightly lighter,suggesting that the gases would be mixing of coal-type gases as a main member and oil-type gases.There are multiple reversals in carbon isotopes for gaseous alkanes,especially abnormal reversal for methane and ethane(i.e.δ13C 1 >δ13C 2 ),inferring that gases would be mixed between high-mature coal-formed gases and oil-type gases.In the Mesozoic,the δ13Cvalues for gaseous alkanes are enriched in 12C,indicating that the gases are mainly derived from sapropelic sources;the carbon isotopic reversal for propane and butane in the Mesozoic is caused by microbial oxidation and mixing of gases from sapropelic sources with different maturity.In contrast to the Upper Paleozoic gases,the Mesozoic gases are characterized by heavier carbon isotopes of iso-butane than normal butane,which may be caused by gases generated from different kerogen types. Finally,according toδ13C 1 -Ro relationship and extremely low total organic carbon contents,the Low Paleozoic gases would not be generated from the Ordovician source as a main gas source,bycontrast, the Upper Paleozoic source as a main gas source is contributed to the Lower Paleozoic gases. | HU AnPing 1 ,Li Jian 2 ,ZHANG WenZheng 3 ,LI ZhiSheng 2 ,HOU Lu 4 &LIU QuanYou 5 1 Department of Earth Sciences,Zhejiang University,Hangzhou 310027,China 2 Langfang Branch,Reasearch Institute of Petroleum Exploration and Development,PetroChina,Langfang 065007,China 3 Institute of Exploration and Development,PetroChina Changqing Oilfield Company,Xi’an 710021,China 4 University of Petroleum,Beijing102249,China 5 PetroChina Research Institute of Petroleum Exploration and Development,Beijing 100083,China | 2008 | Science China Earth Sciences2008，51，S1： | 6 |
| 5 | An ATF24 peptide-functionalized β-elemene-nanostructured lipid carrier combined with cisplatin for bladder cancer treatment显示文摘Objective:In this study,we aimed to develop an amino-terminal fragment(ATF)peptide-targeted liposome carryingβ-elemene(ATF24-PEG-Lipo-β-E)for targeted delivery into urokinase plasminogen activator receptor-overexpressing bladder cancer cells combined with cisplatin(DDP)for bladder cancer treatment.Methods:The liposomes were prepared by ethanol injection and high-pressure microjet homogenization.The liposomes were characterized,and the drug content,entrapment efficiency,andin vitro release were studied.The targeting efficiency was investigated using confocal microscopy,ultra-fast liquid chromatography,and an orthotopic bladder cancer model.The effects of ATF24-PEG-Lipo-β-E combined with DDP on cell viability and proliferation were evaluated by a Cell Counting Kit-8(CCK-8)assay,a colony formation assay,and cell apoptosis and cell cycle analyses.The anticancer effects were evaluated in a KU-19-19 bladder cancer xenograft model.Results:ATF24-PEG-Lipo-β-E had small and uniform sizes(~79 nm),high drug loading capacity(~5.24 mg/mL),high entrapment efficiency(98.37±0.95%),and exhibited sustained drug release behavior.ATF24-PEG-Lipo-β-E had better targeting efficiency and higher cytotoxicity than polyethylene glycol(PEG)ylatedβ-elemene liposomes(PEG-Lipo-β-E).DDP,combined with ATF24-PEG-Lipo-β-E,exerted a synergistic effect on cellular apoptosis and cell arrest at the G2/M phase,and these effects were dependent on the caspase-dependent pathway and Cdc25C/Cdc2/cyclin B1 pathways.Furthermore,thein vivo antitumor activity showed that the targeted liposomes effectively inhibited the growth of tumors,using the combined strategy.Conclusions:The present study provided an effective strategy for the targeted delivery ofβ-elemene(β-E)to bladder cancer,and a combined strategy for bladder cancer treatment. | Bingtao Zhai Peng Chen Wengang Wang Shuiping Liu Jiao Feng Ting Duan Yu Xiang Ruonan Zhang Mingming Zhang Xuemeng Han Xiaying Chen Qiujie Li Guohua Li Ying Liu Xingxing Huang Wenzheng Zhang Ting Pan Lili Yan Ting Jin Tian Xie Xinbing Sui | 2020 | Cancer Biology & Medicine2020，17，3： | 5 |
| 6 | Origin and Accumulation of Natural Gases in the Upper Paleozoic Strata of the Ordos Basin in Central China显示文摘在 Ordos 盆的上面的古生代的阶层的天然气被气体的链烷的相对重的 C 同位素与δ
13 C 1和δ
13 C 2价值主要从 35 ‰ 到 30 ‰ 和 27 ‰ 到 22 ‰,分别地高δ
13在在有超过 0.95 的大多数 C 1/(C1-C5)比率的烃气体的乙烷和甲烷和占优势的甲烷之间的 C 旅行(回合 10 ),建议导出煤的气体的起源。气体展出为天然气的有那些的 C 1-C4 链烷的同位素的侧面发现了在的不同的碳更低这盆古生代,并且相信了从含碳二叠的煤措施被发源。地区性弥漫的煤气的累积的出现在中央盆的轻轻地向南方蘸的 Shanbei 斜坡是不同的。在各种各样的煤气的水库的气体的分子、同位素的作文变化与煤气的来源岩石的热成熟被联系,这被注意。丰富和 δ
13 甲烷的 C 价值通常向北并且从盆中心衰退到它的边缘,并且组合修正上的烃移植的效果似乎不足道。然而,在水库的垂直、侧面的节的单性生植方解石的 C 同位素显示出一个常规变化,并且总体上向上并且向盆边缘被弄空。有煤气的成熟坡度的联合,分析能被认为是为煤气的移植的一个有用工具。 | ZHU Yangming WANG Jibao LIU Xinse ZHANG Wenzheng | 2009 | Acta Geologica Sinica(English Edition)2009，83，1： | 5 |
| 7 | Comparative Proteomic Analysis of Arabidopsis Mature Pollen and Germinated Pollen显示文摘Proteomic analysis was applied to generating the map of Arabidopsis mature pollen proteins and analyzing the differentially expressed proteins that are potentially involved in the regulation of Arabidopsis pollen germination.By applying 2-D electrophoresis and silver staining,we resolved 499 and 494 protein spots from protein samples extracted from pollen grains and pollen tubes,respectively.Using the matrix-assisted laser desorption ionization time-of-flight mass spectrometry method,we identified 189 distinct proteins from 213 protein spots expressed in mature pollen or pollen tubes,and 75 new identified proteins that had not been reported before in research into the Arabidopsis pollen proteome.Comparative analysis revealed that 40 protein spots exhibit reproducible significant changes between mature pollen and pollen tubes.And 21 proteins from 17 downregulated and six upregulated protein spots were identified.Functional category analysis indicated that these differentially expressed proteins mainly involved in signaling,cellular structure,transport,defense/stress responses,transcription,metabolism,and energy production.The patterns of changes at protein level suggested the important roles for energy metabolism-related proteins in pollen tube growth,accompanied by the activation of the stress response pathway and modifications to the cell wall. | Junjie Zou Lianfen Song Wenzheng Zhang Yi Wang Songlin Ruan Wei-Hua Wu | 2009 | Journal of Integrative Plant Biology2009，51，5： | 5 |
| 8 | PCDH17 increases the sensitivity of colorectal cancer to 5-fluorouracil treatment by inducing apoptosis and autophagic cell death显示文摘5-Fluorouracil(5-FU)is known as a first-line chemotherapeutic agent against colorectal cancer(CRC),but drug resistance occurs frequently and significantly limits its clinical success.Our previous study showed that the protocadherin 17(PCDH17)gene was frequently methylated and functioned as a tumor suppressor in CRC.However,the relationship between PCDH17 and 5-FU resistance in CRC remains unclear.Here,we revealed that PCDH17 was more highly expressed in 5-FU-sensitive CRC tissues than in 5-FU-resistant CRC tissues,and high expression of PCDH17 was correlated with high BECN1 expression.Moreover,this expression profile contributed to superior prognosis and increased survival in CRC patients.Restoring PCDH17 expression augmented the 5-FU sensitivity of CRC in vitro and in vivo by promoting apoptosis and autophagic cell death.Furthermore,autophagy played a dominant role in PCDH17-induced cell death,as an autophagy inhibitor blocked cell death to a greater extent than the pancaspase inhibitor Z-VAD-FMK.PCDH17 inhibition by siRNA decreased the autophagy response and 5-FU sensitivity.Mechanistically,we showed that c-Jun NH2-terminal kinase(JNK)activation was a key determinant in PCDH17-induced autophagy.The compound SP600125,an inhibitor of JNK,suppressed autophagy and 5-FU-induced cell death in PCDH17-reexpressing CRC cells.Taken together,our findings suggest for the first time that PCDH17 increases the sensitivity of CRC to 5-FU treatment by inducing apoptosis and JNK-dependent autophagic cell death.PCDH17 may be a potential prognostic marker for predicting 5-FU sensitivity in CRC patients. | Shuiping Liu Haoming Lin Da Wang Qiang Li Hong Luo Guoxiong Li Xiaohui Chen Yongqiang Li Peng Chen Bingtao Zhai Wengang Wang Ruonan Zhang Bi Chen Mingming Zhang Xuemeng Han Qiujie Li Liuxi Chen Ying Liu Xiaying Chen Guohua Li Yu Xiang Ting Duan Jiao Feng Jianshu Lou Xingxing Huang Qin Zhang Ting Pan Lili Yan Ting Jin Wenzheng Zhang Lvjia Zhuo Yitian Sun Tian Xie Xinbing Sui | 2019 | Signal Transduction and Targeted Therapy2019，4，1： | 4 |
| 9 | Design and experiment of anti-vibrating and anti-wrapping rotary components for subsoiler cum rotary tiller显示文摘The commonly used subsoiling cum rotary tiller machine(SRT)in Northern China is a combination of subsoiler and horizontal rotary tiller,however backfilling of the subsoiling slot,excessive vibration and plant residue wrapping on rotary components has been rarely considered.Therefore,the rotary components and assembly were redesigned to address these issues and to an SRT fitted with IT225 short curve rotary blades behind the V-shape subsoiling slots and IIT245 long curve rotary blades between the tines.Long and short blades were fitted on a rotor in a double helix,with optimal spiral angles of 65° and 90°,and phase angle of 147°and 180°,respectively.Compared with the commonly used SRT(CSRT),the additional anti-wrapping cutting blades in the circumferential and axial direction of ASRT could remove hanging residue on the blade holders,wrapping on the rotor and formation of an isolation layer.Moreover,the cutting edge curve of anti-wrapping cutting blades was an exponential curve.Field tests demonstrated that the redesigned SRT with anti-vibrating and anti-wrapping rotary components(ASRT)had was a significant advancement over the CSRT.Moreover,the working depth of rotary tillage was more stable,while other observations confirmed that backfilling of the subsoiling slot was also improved. | Kan Zheng Allen D.McHugh Hongwen Li Qingjie Wang Caiyun Lu Hongnan Hu Wenzheng Liu Zhiqiang Zhang Peng Liu Jin He | 2019 | International Journal of Agricultural and Biological Engineering2019，12，4： | 4 |
| 10 | On the development mechanism of the lacustrine high-grade hydrocarbon source rocks of Chang 91 member in Ordos Basin显示文摘As revealed from recent drilling and organic geochemical testing and research, a series of lacustrine high-grade hydrocarbon source rocks was discovered in the upper section of the Chang 9 oil reservoir member of upper Triassic in Ordos Basin. The hydrocarbon source rocks show average TOC content as high as 5.03%, average bitumen 'A' content as high as 0.8603%, and good quality organic precursors, which are of the sapropelic type mainly derived from lower aquatic plants and have reached the thermal evolution stage featured by oil-producing climax. Generally the lacustrine high-grade hydrocarbon source rocks were developed in local depressions of a lake basin, and the Chang 91 member was particularly formed in a depositional environment characterized by fresh water to weakly saline water, weakly oxidizing to weakly reducing setting and semi-deep lake facies, as was demonstrated by a variety of organic to inorganic geochemical parameters. As a result, high productivity constitutes the principal controlling force for generation of this series of high-grade hydrocarbon source rocks. Deposition of thinly-bedded and laminated tuffs as well as positive Eu anomaly corroborate the possible occurrence of anoxic geological event closely related to contemporaneous volcanic eruption, which would play a key part in development of the Chang 91 member of high-grade hydrocarbon source rocks. | ZHANG WenZheng YANG Hua FU SuoTang ZAN ChuanLi | 2007 | Science China Earth Sciences2007，50，z2： | 4 |
| 11 | Prognostic value of pre-and post-transplantation 18F-fluorodeoxyglucose positron emission tomography results in non-Hodgkin lymphoma patients receiving autologous stem cell transplantation显示文摘Objective: High-dose chemotherapy(HDC) followed by autologous stem cell transplantation(ASCT) is the standard of care in the upfront or relapsed/refractory setting in some patients with non-Hodgkin lymphoma(NHL).However,a proportion of patients do not respond to ASCT.^(18)F-fluorodeoxyglucose(FDG) positron emission tomography(PET)/computed tomography(CT) has been widely used for staging,response evaluation,and prognosis prediction.Here,we investigated the prognostic role of PET/CT in NHL patients before and after ASCT.Methods: A retrospective study was conducted at Peking University Cancer Hospital.All NHL patients who underwent ASCT between March 2010 and July 2016 were identified.Patients who had PET/CT scan before and after ASCT were included.Deauville criteria(5-point scale) were used to interpret PET scans.Univariate and multivariate survival analyses were performed using Cox regression.The predictive value of PET scanning was estimated by comparing the area under the receiver operating characteristic(ROC) curve.Results: In total,79 patients were enrolled in this study.In univariate analysis,pre-and post-ASCT PET result was identified as prognostic factors for 3-year progression-free survival(PFS) and overall survival(OS).Patients with negative pre-ASCT PET result demonstrated significantly better PFS(84.2% vs.54.2%) and OS(89.2% vs.63.6%) than patients with positive pre-ASCT PET result.PFS(91.6% vs.25.3%) and OS(96.5% vs.36.8%) were also significantly different between patients with negative and positive post-ASCT PET result.Multivariate analysis also showed a significant association between survival and post-ASCT PET result.ROC analysis revealed that the predictive value of post-ASCT PET result was superior to that of pre-ASCT PET result alone.Combined pre-and post-ASCT PET result is better for predicting outcomes in patients with NHL receiving transplantation.Deauville criteria score >3 was identified as the best cutoff value for post-ASCT PET.Conclusions: Post-ASCT PET result was more important than pre-ASCT PET result in predicting outcomes for NHL patients who underwent ASCT.The prognostic significance can be improved when combining preASCT PET result with post-ASCT PET result.Deauville criteria can be used for interpreting PET scans in this scenario. | Zhitao Ying Lan Mi Xuejuan Wang Yuewei Zhang Zhi Yang Yuqin Song Xiaopei Wang WenZheng Ningjing Lin Meifeng Tu Yan Xie Lingyan Ping Chen Zhang Weiping Liu LijuanDeng Jun Zhu | 2017 | Chinese Journal of Cancer Research2017，29，6： | 3 |
| 12 | Primary migration and secondary alteration of the Upper Paleozoic gas reservoir in Ordos Basin,China―Application of fluid inclusion gases显示文摘The composition of fluid inclusions(FI)often represents the initial geochemical characteristics of palaeo-fluid in reservoir rock.Influence on composition and carbon isotopic composition of gas during primary migration,reservoir-forming and subsequent secondary alterations are discussed through comparing fluid inclusion gas with coal-formed gas and natural gas in present gas reservoirs in the Ordos Basin.The results show that primary migration of gas has significant effect on the molecular but not on the carbon isotopic composition of methane.Migration and diffusion fractionation took place during the secondary migration of gas in Upper Paleozoic gas reservoir according to carbon isotopic composition of methane in FIs.Composition and carbon isotopic composition of natural gas were nearly unchanged after the gas reservoir forming through comparing the FI gases with the natural gas in present gas reservoir. | GONG Se 1,2 ,PENG PingAn 1 ,SHUAI YanHua 3 ,DAI JinXing 3 &ZHANG WenZheng 4 1 Guangzhou Institute of Geochemistry,the Chinese Academy of Sciences,Guangzhou 510640,China 2 Common Wealth Scientific and Research Organization,Petroleum Resources,PO Box 136,North Ryde,New South Wales,1670,Australia 3 Research Institute of Petroleum Exploration and Development,PetroChina,Beijing 100083,China 4 Research Institute of Exploration and Development,Changqing Petroleum Corporation,Xi’an 710021,China | 2008 | Science China Earth Sciences2008，51，S1： | 3 |
| 13 | Pre-chamber turbulent jet ignition of methane/air mixtures with multiple orifices in a large bore constant volume chamber: effect of air-fuel equivalence ratio and pre-mixed pressure显示文摘Liquefied natural gas (LNG), mainly composed of methane, is in progress to substitute diesel fuel in heavyduty marine engine for practical, economic, and environmental considerations. However, natural gas is relatively difficult to be ignited in a large bore combustion chamber. A combustion enhancement technique called prechamber turbulent jet ignition (TJI) can permit combustion and flame propagation in a largebore volume. To investigate the effect of air-fuel equivalence ratio and pre-mixed pressure on pre-chamber TJI of methane/air mixtures with multiple orifices in a large bore volume, experimental tests and computational simulations were implemented to study the discharge of hot turbulent jets from six orifices of the pre-chamber. Different initial pressures and air-fuel equivalence ratios were considered to analyze the characteristics of TJI. The asymmetry of the turbulent jet actuated from six different orifices were found due to the asymmetric orientation of the spark plug, resulting in the inhomogeneous distribution of combustion in the constant volume chamber, which should be considered seriously in the marine engine design. Besides,as the premixed pressure increases, it has more effect on the flame propagation and plays a more important role, as it further increases. | Xiang LI Wenzheng ZHANG Zhong HUANG Dehao JU Li HUANG Mingzhi FENG Xingcai LU Zhen HUANG | 2019 | Frontiers in Energy2019，13，3： | 3 |
| 14 | 全雄激素阻断前后前列腺癌细胞中Bcl-2和Bcl-X_L基因表达改变显示文摘 | 叶定伟 Hui Li Wenzheng Zhang 方银忠 戴波 张海梁 沈益君 | 2004 | 中华泌尿外科杂志2004，25，6： | 2 |
| 15 | Geochemical characteristics and source rock of Ordovician gas reservoir, Changqing Gasfield显示文摘Carbon isotopic composition of methane in Ordovician gas reservoir in the Changqing Gasfield can reflect the dominance of Upper Paleozoic coal-type gas despite its high mature degree. The 12C-rich ethane in the Ordovician reservoir (δ13C2 < - 29‰), known as a marker as oil-type gas, does not indicate the Ordovician marine carbonate as main source rock, it is be- | XIA Xinyu, ZHAO Lin, ZHANG Wenzheng and LI JianfengResearch Institute of Petroleum Exploration and Development, Beijing 100083, China Changqing Petroleum Exploration Bureau, XL an 710021 , China | 1999 | Chinese Science Bulletin1999，44，20： | 2 |
| 16 | Nonlinear Vibration Analyses of Cylindrical Shells Composed of Hyperelastic Materials显示文摘The nonlinear vibration problem is studied for a thin-walled rubber cylindrical shell composed of the classical incompressible Mooney-Rivlin material and subjected to a radial harmonic excitation. With the KirchhofF-Love hypothesis, DonnelFs nonlinear shallow shell theory, hyperelastic constitutive relation, Lagrange equations and small strain hypothesis, a system of nonlinear differential equations describing the large-deflection vibration of the shell is derived. First, the natural frequencies of radial, circumferential and axial vibrations axe studied. Then, based on the bifurcation diagrams and the Poincare sections, the nonlinear behaviors describing the radial vibration of the shell are illustrated. Examining the influences of structural and material parameters on radial vibration of the shell shows that the vibration modes are highly sensitive to the thickness-radius ratio when the ratio is less than a certain critical value. Moreover, in terms of the results of multimodal expansion, it is found that the response of the shell to radial motion is more regular than that without considering the coupling between modes, while there are more phenomena for the uncoupled case. | Jing Zhang Jie Xu Xuegang Yuan Hu Ding Datian Niu Wenzheng Zhang | 2019 | Acta Mechanica Solida Sinica2019，32，4： | 2 |
| 17 | Threshold public key encryption scheme resilient against continual leakage without random oracles显示文摘 | Xiujie ZHANG Chunxiang XU Wenzheng ZHANG Wanpeng LI | 2013 | Frontiers of Computer Science2013，7，6： | 2 |
| 18 | FINITE DEFORMATION OF A CLASS OF RECTANGULAR RUBBER RINGS SUBJECTED TO END AXIAL LOADS显示文摘The problem of finite deformation of an incompressible rectangular rubber ring with an internal rigid body, where the ring is subjected to equal axial loads at its two ends, is examined. A reasonable mathematical model is formulated by using the nonlinear field theory and the implicit analytical solutions are derived. Then numerical simulations are implemented to further illustrate the results and obtain some meaningful conclusions. The deformation of the lateral surface of the ring becomes larger with the increasing axial loads, the decreasing ratio of the inner and outer radii and the increasing height of the ring. | Wenzheng Zhang Xuegang Yuan Hongwu Zhang Jiusheng Ren | 2012 | Acta Mechanica Solida Sinica2012，25，2： | 2 |
| 19 | Dynamic cavitations in incompressible hyperelastic pre-strained circular sheets显示文摘A class of dynamic cavitations is examined for an isotropic incompressible hyperelastic circular sheet under a pre-strained state caused by an initially applied finite radial tension.The solutions that describe the radially symmetric motion of the pre-strained sheet are obtained.The conditions of cavitated bifurcation that describe cavity formation and motion with time at the axial line of the pre-strained sheet are proposed,that is to say,a circular cavity will form if the suddenly applied radial tensile load exceeds a certain critical value;dynamically,it is proved that the formed cavity will present a nonlinearly periodic oscillation,which is essentially different from the singular periodic oscillation of the formed cavity in an incompressible hyperelastic solid sphere.Numerical simulations show the effects of prescribed radial tension,material parameter and tensile load on critical ten-sile load describing cavity formation and periodic oscillation of the pre-strained circular sheet. | YUAN XueGang ZHANG HongWu ZHANG WenZheng ZHAO Wei Dong Bin | 2011 | Science China(Physics,Mechanics & Astronomy)2011，54，2： | 1 |
| 20 | Secure Medical Information Sharing in Cloud Computing显示文摘 | Shao Zhiyi Yang Bo Zhang Wenzheng | 2015 | Technology and Health Care2015，23，1： | 1 |
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