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| 1 | A meta-analysis of Chinese herbal medicines for vascular dementia显示文摘OBJECTIVE: To investigate the efficacy and safety of Chinese herbal medicines in the treatment of patients with vascular dementia. DATA RETRIEVAL: We retrieved publications from Cochrane Library (2004 to July 2011), PubMed (1966 to July 2011), the Chinese Science and Technique Journals Database (1977 to July 2011), the China National Knowledge Infrastructure (1979 to July 2011), Google Scholar (July 2011), and the Chinese Biomedical Database (1977 to July 2011) using the'Chinese medicine OR Chinese herbal medicine' and 'vascular dementia OR mild cognition impair OR multi-infarct dementia OR small-vessel dementia OR strategic infarct dementia OR hypoperfusion dementia OR hemorrhagic dementia OR hereditary vascular dementia'. SELECTION CRITERIA: Randomized controlled trials comparing Chinese herbal medicines with placebo/western medicine in the treatment of patients with vascular dementia were included. Diagnostic standards included Diagnostic and Statistical Manual of Mental Disorders-IV, and National Institute of Neurological Disorders and Stroke and Association Internationale pour la Recherché et l'Enseignement en Neurosciences. Two participants independently conducted literature screening, quality evaluation and data extraction. The quality of each trial was assessed according to the Cochrane Reviewers' Handbook 5.0. MAIN OUTCOME MEASURES: Effective rate, Mini-Mental State Examination scores, Hasegawa Dementia Scale scores, and incidence of adverse reactions. RESULTS: We identified 1 143 articles discussing the effects of Chinese medicine on vascular dementia. Thirty-one of these were included in the analysis. These studies involved a total of 2 868 participants (1 605 patients took Chinese medicine decoctions (treatment group); 1 263 patients took western medicine or placebo). The results of our meta-analysis revealed that Chinese herbal remedies in the treatment group were more efficacious than the control intervention (relative risk (RR)=1.27; 95% confidence interval (CI): 1.18-1.38, P<0.01). Mini-Mental State Examination scores were higher in patients taking Chinese herbal medicines than in those in the control group (weighted mean difference (WMD)=2.83; 95%CI: 2.55-3.12, P<0.01). Patients in the treatment group showed better disease amelioration than those in the control group (Hasegawa Dementia Scale scores; WMD=2.41, 95%CI: 1.48-3.34, P<0.01). There were also considerably fewer adverse reactions among those in the treatment group compared with those in the control group (RR=0.20, 95%CI: 0.08-0.47, P<0.01). CONCLUSION: Chinese herbal medicine appears to be safer and more effective than control measures in the treatment of vascular dementia. However, the included trials were generally low in quality. More well-designed, high-quality trials are needed to provide better evidence for the assessment of the efficacy and safety of Chinese medicines for vascular dementia. | Xiude Qin Yu Liu Yanqing Wu Shuo Wang Dandan Wang Jinqiang Zhu Qiaofeng Ye Wei Mou Liyuan Kang | 2013 | Neural Regeneration Research2013，8，18： | 7 |
| 2 | Symptoms of long-term exposure to moxa smoke in acupuncturists: a correlation analysis显示文摘OBJECTIVE: To investigate the effects of long-term exposure to moxa smoke on acupuncturists and to consider the association between physical symptoms and gender, age, secondhand smoke(SHS) exposure, and the duration of exposure.METHODS: A self-report, web-based questionnaire was used to evaluate the effects of moxa smoke onacupuncturists. Logistic regression was used to analyze the relationship between physical symptoms and possible correlative factors.RESULTS: A total of 858 questionnaires were analyzed. The data showed that 42.42% of acupuncturists had been exposed to moxa smoke for 5-10 years. The most frequent symptom was tearing(32.98%) and the least frequent symptom was asthma(5.24%). Logistic regression analysis showed that female acupuncturists were slightly more susceptible to cough and tearing than males(cough:OR: 1.583, 95% CI: 1.079, 2.321, P = 0.019; tearing:OR: 1.519, 95% CI: 1.094, 2.108, P = 0.013). Acupuncturists aged over 25 years reported a slightly lower incidence of eye itchiness than those aged under25 years(26-40 years: OR: 0.604, 95% CI: 0.379,0.965, P = 0.035; over 40 years: OR: 0.330, 95% CI:0.114, 0.958, P = 0.042). Ophthalmodynia occurred less in acupuncturists aged 26-40 years(OR: 0.591,95% CI: 0.359, 0.970, P = 0.038) than in those younger than 25 years. The only association between prevalence of symptoms and tobacco use and SHS exposure was that smokers had a lower occurrence of phlegm in the throat(OR: 0.579, 95% CI: 0.392,0.856, P = 0.006). Shortness of breath was less frequent in participants exposed to moxa smoke for more than 5 years(5-10 years: OR: 0.400, 95% CI:0.204, 0.785, P = 0.008; 11-20 years: OR: 0.392, 95%CI: 0.178, 0.864, P = 0.02), but a slightly higher incidence of eye itchiness was found in those with over20 years of moxa exposure(OR: 4.200, 95% CI:1.344, 3.128, P = 0.014).CONCLUSION: The most frequent symptom of moxa smoke exposure in acupuncturists was tear-ing. The association of symptoms with age and duration of exposure to moxa smoke were rather complicated; hence, care should be taken in drawing conclusions about the safety of moxa smoke based solely on its potentially harmful ingredients. | Wang Xiang Yu Chang Tang Yong Chang Shyang Yang Hui Zhang He Jiaozi Zhang Yueyue Jiao Yang Zhuang Zhiqi Yin Haiyan Zhang Chengshun Lu Peng Wu Qiaofeng Yu Shuguang | 2018 | Journal of Traditional Chinese Medicine2018，38，1： | 7 |
| 3 | Different manual manipulations and electrical parameters exert different therapeutic effects of acupuncture显示文摘Acupuncture is an important component part of Traditional Chinese Medicine(TCM). The therapeutic effects may be influenced by a variety of factors.Stimulation quantity is one of the factors for achieving good therapeutic effects in acupuncture practice. With the development of science and technology, besides the influence of manual manipulations, the parameters adopted for electroacupuncture have become the benchmark of stimulation quantity. This study, by referring to the related literatures, is designed to explore the influence of manual manipulations and electrical parameters on therapeutic effects of acupuncture. The results from the present study show that different manualmanipulations and electrical parameters may exert different therapeutic effects of acupuncture, which are closely related to the characteristics of diseases.Different manual manipulations and electrical parameters should be adopted according to syndrome differentiation of TCM. This is very important in acupuncture treatment. | Zheng Yu Lu Luo Yu Li Qiaofeng Wu Shufang Deng Shouying Lian Fanrong Liang | 2014 | Journal of Traditional Chinese Medicine2014，34，6： | 5 |
| 4 | lH NMR-based metabonomic study on the metabolic changes in the plasma of patients with functional dyspepsia and the effect of acupuncture显示文摘 | Qiaofeng Wu Qi Zhang Bo Sun etal | 2010 | Journal of Pharmaceutical and Biomedical Analysis2010，51，3： | 1 |
| 5 | Acoustic aligning and trapping of microbubbles in an enclosed PDMS microfluidic device显示文摘 | Long Meng Feiyan Cai Qiaofeng Jin Lili Niu Chunxiang Jiang Zhanhui Wang Junru Wu Hairong Zheng | 2011 | Sensors & Actuators: B Chemical2011，，1： | 1 |
| 6 | Genetic analysis and molecular mapping of a new powdery mildew resistant gene Pm46 in common wheat显示文摘 | Haidong Gao Fangfang Zhu Yanjie Jiang Jizhong Wu Wei Yan Qiaofeng Zhang Andreas Jacobi Shibin Cai | 2012 | Theoretical and Applied Genetics2012，，： | 1 |
| 7 | Paclitaxel-liposome–microbubble complexes as ultrasound-triggered therapeutic drug delivery carriers显示文摘 | Fei Yan Lu Li Zhiting Deng Qiaofeng Jin Juanjuan Chen Wei Yang Chih-Kuang Yeh Junru Wu Robin Shandas Xin Liu Hairong Zheng | 2013 | Journal of Controlled Release2013，，3： | 1 |
| 8 | Acoustic aligning and trapping of microbubbles in an enclosed PDMS microfluidic device显示文摘 | Long Meng Feiyan Cai Qiaofeng Jin Lili Niu Chunxiang Jiang Zhanhui Wang Junru Wu Hairong Zheng | 2011 | Sensors & Actuators: B Chemical2011，，1： | 1 |
| 9 | Paclitaxel-liposome–microbubble complexes as ultrasound-triggered therapeutic drug delivery carriers显示文摘 | Fei Yan Lu Li Zhiting Deng Qiaofeng Jin Juanjuan Chen Wei Yang Chih-Kuang Yeh Junru Wu Robin Shandas Xin Liu Hairong Zheng | 2013 | Journal of Controlled Release2013，，3： | 1 |
| 10 | Acoustic aligning and trapping of microbubbles in an enclosed PDMS microfluidic device显示文摘 | Long Meng Feiyan Cai Qiaofeng Jin Lili Niu Chunxiang Jiang Zhanhui Wang Junru Wu Hairong Zheng | 2011 | Sensors & Actuators: B Chemical2011，，1： | 1 |
| 11 | Mammary cell proliferation and catabolism of adipose tissues in nutrition-restricted lactating sows were associated with extracellular high glutamate levels显示文摘Background: Persistent lactation,as the result of mammary cellular anabolism and secreting function,is dependent on substantial mobilization or catabolism of body reserves under nutritional deficiency.However,little is known about the biochemical mechanisms for nutrition-restricted lactating animals to simultaneously maintain the anabolism of mammary cells while catabolism of body reserves.In present study,lactating sows with restricted feed allowance(RFA)(n = 6),24% feed restriction compared with the control(CON) group(n = 6),were used as the nutrition-restricted model.Microdialysis and mammary venous cannulas methods were used to monitor postprandial dynamic changes of metabolites in adipose and mammary tissues.Results: At lactation d 28,the RFA group showed higher(P < 0.05) loss of body weight and backfat than the CON group.Compared with the CON group,the adipose tissue of the RFA group had higher(P < 0.05) extracellular glutamate and insulin levels,increased(P < 0.05) lipolysis related genes(HSL and ATGL) expression,and decreased(P < 0.05) glucose transport and metabolism related genes(VAMP8,PKLR and LDHB) expression.These results indicated that under nutritional restriction,reduced insulin-mediated glucose uptake and metabolism and increased lipolysis in adipose tissues was related to extracellular high glutamate concentration.As for mammary glands,compared with the CON group,the RFA group had up-regulated(P < 0.05) expression of Notch signaling ligand(DLL3) and receptors(NOTCH2 and NOTCH4),higher(P < 0.05) extracellular glutamate concentration,while expression of cell proliferation related genes and concentrations of most metabolites in mammary veins were not different(P > 0.05) between groups.Accordingly,piglet performance and milk yield did not differ(P > 0.05) between groups.It would appear that activation of Notch signaling and adequate supply of glutamate might assist mammogenesis.Conclusions: Mammary cell proliferation and catabolism of adipose tissues in nutrition-restricted lactating sows were associated with extracellular high glutamate levels. | Heju Zhong Peng Wang Yumo Song Xiaoling Zhang Lianqiang Che Bin Feng Yan Lin Shengyu Xu Jian Li De Wu Qiaofeng Wu Zhengfeng Fang | 2019 | Journal of Animal Science and Biotechnology2019，10，1： | 0 |
| 12 | Ultra-smooth CsPbI_(2)Br film via programmable crystallization process for high-efficiency inorganic perovskite solar cells显示文摘CsPbI_(2)Br is an ideal inorganic perovskite material with a reasonable bandgap for solar cell applications because of its advantage of superior thermal and phase stability. However, the performance of CsPbI2Br based solar cells highly relied on the perovskite crystallization process along with the interfacial contact engineering process between CsPbI_(2)Br perovskite and charge-transporting layers. In this work, a programmable crystallization method is developed to obtain ultra-smooth CsPbI_(2)Br perovskite film with a well-engineered contact interface in perovskite solar cells. This method combines a pre-stand-by process with a programmable gradient thermal engineering process, which mediates the crystal growth dynamics process of CsPbI2Br perovskite by controlling the release of dimethyl sulfoxide(DMSO) from its coordinates with the perovskite film, leading to high-quality CsPbI_(2)Br film with large-scale crystalline grains, reduced surface roughness, and low trap density. Fabricated perovskite devices based on CsPbI_(2)Br film obtained by this method deliver power conversion efficiency of 14.55 %;meanwhile, the encapsulated CsPbI_(2)Br perovskite device achieves a maximum efficiency of 15.07 %. This decent solar conversion efficiency demonstrates the effectiveness of the programmable crystallization method used in this work,which shows great potential as a universal approach in obtaining high-quality CsPbI_(2)Br perovskite films for fabricating high-efficiency inorganic perovskite solar cells. | Fu Zhang Zhu Ma Taotao Hua Rui Liu Qiaofeng Wu Yu Yue Hua Zhang Zheng Xiao Meng Zhang Wenfeng Zhang Xin Chen Hua Yu | 2021 | Journal of Materials Science & Technology2021，，7： | 0 |
| 13 | Aggregation-induced emission in luminescent metal nanoclusters显示文摘Few-to hundred-atom luminescent metal nanoclusters(NCs)protected by an organic monolayer have recently emerged as a novel class of chromophores,with facile preparation,ultrafine size,low toxicity,high renal clearance and excellent photostability[1].Luminescent metal NCs hold great promise for broad applications in lighting,imaging,sensing and therapeutics[2];however,the unsatisfactory emission intensity of metal NCs has constrained their further practical applications. | Zhennan Wu Qiaofeng Yao Shuang-quan Zang Jianping Xie | 2021 | National Science Review2021，8，6： | 0 |
| 14 | Small molecule interfacial cross-linker for highly efficient two-dimensional perovskite solar cells显示文摘The nonradiative recombination of charge carriers at the hole transport layer(HTL)/perovskite interface generally induces remarkable performance loss of the inverted two-dimensional perovskite solar cells(2D PSCs). Herein, a cross-linkable small molecule of 2-mercaptoimidazole(2-MI) was introduced into the nickel oxide(NiO_(x))/2D perovskite interface. Experiments have confirmed the formation of Ni-N covalent bond by N atom in the 2-MI and Ni in the NiO_(x) and the coordinating between S atom of 2-MI and under-coordinated Pb^(2+) near to the NiO_(x)/perovskite interface, which contributes to creating a crosslinking between NiO_(x)/perovskite interface to restrain charge carrier recombination and enhance the extraction of hole carriers at the interface. Besides, the 2-MI modification layer is also beneficial for promoting the crystallinity of 2D perovskite. Consequently, the inverted 2D PSCs with 2-MI modification achieved the best power conversion efficiency of 15%. This paves a route to acquire highly efficient 2D PSCs by constructing a cross-linking at the NiO_(x)HTL/2D perovskite interface. | Hongming Hou Taotao Hu Fu Zhang Rui Liu Jialong He Chang Liu Yue Yu Dong Chen Qiaofeng Wu Meng Zhang Hua Yu | 2022 | Journal of Energy Chemistry2022，31，5： | 0 |
| 15 | Synthesis of CdS multipods from cadmium xanthate in ethylenediamine solution显示文摘CdS nanocrystals of various shapes were synthesized by using cadmium ethyldithiocarbonatio(xanthate)as a single precursor under solvothermal condition.The reaction temperature,cadmium concentration,and solvents determine the CdS morphology.Multipodal CdS structures of different fractions of all particles were obtained at temperatures ranging from 100 to 180 ℃ with the corresponding precursor concentrations in ethylenediamine(EDA) solution.This approach is different from that reported in the literature,where EDA is regarded as a solvent favorable to the formation of CdS nanorods instead of pods.Uniform CdS multipods were prepared at 160℃ with 1.0g of cadmium xanthate.The formation of CdS multipods in EDA solution may be attributed to a synergistic effect between the reaction temperature and Cd concentration,i.e.,thermodynamicaily and kinetically controlled growth of the CdS wurtzite(WZ)and zinc blende(ZB) phases,as confirmed by the structural characterization of the component CdS crystals.EDA and xanthate ligands act as co-assisted capping agents in the growth of CdS multipods.When using N,N-dimethylformamide(DMF) and ethylene glycol(EG) as solvents,the CdS appears as triangular particles and flower-like microspheres assembled by polyhedrons,respectively. | Qiaofeng Han Jin Zhao Lei Wu Junwu Zhu Xin Wang | 2015 | Particuology2015，13，2： | 0 |
| 16 | Structural effects of sulfonamides on the proliferation dynamics of sulfonamide resistance genes in the sequencing batch reactors and the mechanism显示文摘Antibiotic resistance genes(ARGs)can be easily promoted by antibiotics,however,the structural effects of antibiotics on the proliferation of ARGs dynamic and the associated mechanisms remain obscure in,especially,activated sludge sequencing batch reactors.In the present study,the effects of 9 sulfonamides(SAs)with different structures on the proliferation dynamic of sulfonamide resistance genes(Suls)in the activated sludge sequencing batch reactors and the corresponding mechanisms were determined(30 days),and the results showed that the largest proliferation value(ΔA^(R))of Suls dynamic for SAs(sulfachloropyridazine)was approximately 2.9 times than that of the smallest one(sulfadiazine).The proliferation of Suls was significantly related to the structural features(minHBint6,SssNH,SHBd and SpMax2_Bhm)that represent the biological activity of SAs.To interpret the phenomenon,a mechanistic model was developed and the results indicated that the biodegradation of SAs(T_(1/2))rather than conjugative transfer frequency or mutation frequency tends to be the key process for affecting Suls proliferation.T_(1/2)was proved to be dependent on the interactions between SAs and receptors(E_(binding)),the cleavage mode(bond dissociation energy),and the site of nucleophilic assault.Besides,the metagenomic analysis showed that SAs posed significant effect on antibiotic resistome and Tnp31 played a vital role in the proliferation of Suls.Overall,our findings provide important insight into a theoretical basis for understanding the structural effects of SAs on the proliferation of ARGs in SBR systems. | Ligui Wu Mingyu Wang Lingling Rong Wenbiao Wang Linwei Chen Qiaofeng Wu Haoyu Sun Xiangfeng Huang Xiaoming Zou | 2024 | Journal of Environmental Sciences2024，，1： | 0 |
| 17 | Comparing two approaches for introgression of germplasm from Aegilops tauschii into common wheat显示文摘Allelic diversity in the wild grass Aegilops tauschii is vastly greater than that in the D genome of common wheat(Triticum aestivum), of which Ae. tauschii is the source. Since the 1980 s,there have been numerous efforts to harness a much larger share of Ae. tauschii^ extensive and highly variable gene pool for wheat improvement. Those efforts have followed two distinct approaches: production of amphiploids, known as 'synthetic hexaploids,' between T. turgidum and Ae. tauschii,and direct hybridization between 丁. aestiuum and Ae. tauschii;both approaches then involve backcrossing to 丁. aestiuum. Both synthetic hexaploid production and direct hybridization have led to the transfer of numerous new genes into common wheat that confer improvements in many traits. This work has led to release of improved cultivars in China, the United States, and many other countries. Each approach to D-genome improvement has advantages and disadvantages. For example, production of synthetic hexaploids can incorporate useful germplasm from both T. turgidum and Ae.tauschii, thereby enhancing the A, B, and D genomes; on the other hand, direct hybridization rapidly restores the recurrent parent's A and B genomes and avoids incorporation of genes with adverse effects on threshability, hybrid necrosis, vernalization response, milling and baking quality, and other traits, which are often transferred when T. turgidum is used as a parent. Choice of method will depend in part on the type of wheat being developed and the target environment. However, more extensive use of the so-far underexploited direct hybridization approach is especially warranted. | Thomas S.Cox Jizhong Wu Shuwen Wang Jin Cai Qiaofeng Zhong Bisheng Fu | 2017 | The Crop Journal2017，5，5： | 0 |
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