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57篇 您的检索式:作者名="Xianli Wang"
    题名 作者 年代 出处 被引量
1Analysis and Numerical Simulation of Rolling Contact between Sphere and Cone显示文摘In non-conforming rolling contact, the contact stress is highly concentrated in the contact area. However, there are some limitations of the special contact model and stress model used for the theoretical study of the phenomenon, and this has prevented in-depth analysis of the associated friction, wear, and failure. This paper is particularly aimed at investigating the area of rolling contact between a sphere and a cone, for which purpose the boundary is determined by the Hertz theory and the geometries of the non-conforming surfaces. The phenomenon of stick-slip contact is observed to occur in the contact area under the condition of no-full-slip(Q < μ·P). Using the two-dimensional rolling contact theory developed by CARTER, the relative positions of the stick and slip regions and the distribution of the tangential force over the contact area are analyzed. Furthermore, each stress component is calculated based on the Mc Ewen theory and the idea of narrow band. The stress equations for the three-dimensional rolling contact between the sphere and the cone are obtained by the principle of superposition, and are used to perform some numerical simulations. The results show that the stress components have a large gradient along the boundary between the stick and slip regions, and that the maximum stress is inversely proportional to the contact coefficient and proportional to the friction coefficient. A new method for investigating the stress during non-classical three-dimensional rolling contact is proposed as a theoretical foundation for the analysis of the associated friction, wear, and failure.ZHAO Yanling XIA Chengtao WANG Hongbo XUAN Jiaping XIANG Jingzhong LIU Xianli SU Xiangguo 2015Chinese Journal of Mechanical Engineering2015,28,3:18
2A review of chatter vibration research in milling显示文摘Chatter is a self-excited vibration of parts in machining systems. It is widely present across a range of cutting processes, and has an impact upon both efficiency and quality in production processing. A great deal of research has been dedicated to the development of technologies that are able to predict and detect chatter. The purpose of these technologies is to facilitate the avoidance of chatter during cutting processes, which leads to better surface precision, higher productivity,and longer tool life. This paper summarizes the current state of the art in research regarding the problems of how to arrive at stable chatter prediction, chatter identification, and chatter control/-suppression, with a focus on milling processes. Particular focus is placed on the theoretical relationship between cutting chatter and process damping, tool runout, and gyroscopic effect, as well as the importance of this for chatter prediction. The paper concludes with some reflections regarding possible directions for future research in this field.Caixu YUE Haining GAO Xianli LIU Steven Y.LIANG Lihui WANG 2019Chinese Journal of Aeronautics2019,32,2:12
3Novel Insights into Energy Storage Mechanism of Aqueous Rechargeable Zn/MnO2 Batteries with Participation of Mn2+显示文摘Aqueous rechargeable Zn/MnO2 zinc-ion batteries(ZIBs)are reviving recently due to their low cost,non-toxicity,and natural abundance.However,their energy storage mechanism remains controversial due to their complicated electrochemical reactions.Meanwhile,to achieve satisfactory cyclic stability and rate performance of the Zn/MnO2 ZIBs,Mn2+ is introduced in the electrolyte(e.g.,ZnSO4 solution),which leads to more complicated reactions inside the ZIBs systems.Herein,based on comprehensive analysis methods including electrochemical analysis and Pourbaix diagram,we provide novel insights into the energy storage mechanism of Zn/MnO2 batteries in the presence of Mn2+.A complex series of electrochemical reactions with the coparticipation of Zn2+,H+,Mn2+,SO42-,and OH-were revealed.During the first discharge process,co-insertion of Zn2+ and H+ promotes the transformation of MnO2 into ZnxMnO4,MnOOH,and Mn2O3,accompanying with increased electrolyte pH and the formation of ZnSO4·3 Zn(OH)2-5 H2O.During the subsequent charge process,ZnxMnO4,MnOOH,and Mn2O3 revert to a-MnO2 with the extraction of Zn2+ and H+,while ZnSO4·3Zn(OH)2·5H2O reacts with Mn2+ to form ZnMn3O7·3 H2O.In the following charge/discharge processes,besides aforementioned electrochemical reactions,Zn2+ reversibly insert into/extract from α-MnO2,ZnxMnO4,and ZnMn3O7·3H2O hosts;ZnSO4·3Zn(OH)2·5 H2O,Zn2Mn3O8,and ZnMn2O4 convert mutually with the participation of Mn2+.This work is believed to provide theoretical guidance for further research on high-performance ZIBs.Yongfeng Huang Jian Mou Wenbao Liu Xianli Wang Liubing Dong Feiyu Kang Chengjun Xu 2019Nano-Micro Letters2019,11,3:11
4Development and characterization of a cell line from the embryos of half smooth tongue sole (Cynoglossus semilaevis)显示文摘A new cell line,CSEC,has been successfully established from embryos at gastrula stage of a cultured marine fish,half smooth tongue sole(Cynoglossus semilaevis).CSEC cells grow actively and stably more than 50 passages for over 200 d in DMEM medium supplemented with 15% FBS(fetal bovine serum),2.5 ng/cm 3 bFGF(basic fibroblast growth factor),1 ng/cm 3 LIF(leukemia inhibitory factor) and 50 mmol/dm 3 2-ME(2-mecaptoethanol).The cells grew well in the temperature range of 24-30 ℃ and the optimal growth temperature was 24℃.FBS and bFGF concentrations are the two key components for CSEC cells proliferation.Chromosome analysis reveals that CSEC cells have a normal diploid karyotype with 2n=42t.The significant fluorescent signals were observed in CSEC after transfection with the GFP reporter gene,suggesting that the CSEC cell line can be used as a useful tool for transgenic and genetic manipulation studies.CSEC cells showed the cytopathic effect(CPE) after infection with lymphosystis disease virus(LCDV) in 2 d.Moreover,the LCDV particles can be observed in the cytoplasm of virus-infected cells by electron microscopy.It suggests that CSEC could be potentially used for the study of aquatic virus.SHA Zhenxia REN Guocheng WANG Xianli WANG Na CHEN Songlin 2010Acta Oceanologica Sinica2010,29,2:7
5Development and utilization of a new chemically-induced soybean library with a high mutation density显示文摘Mutagenized populations have provided important materials for introducing variation and identifying gene function in plants. In this study, an ethyl methanesulfonate(EMS)-induced soybean(Glycine max) population,consisting of 21,600 independent M_2 lines, was developed.Over 1,000 M_(4(5))families, with diverse abnormal phenotypes for seed composition, seed shape, plant morphology and maturity that are stably expressed across different environments and generations were identified. Phenotypic analysis of the population led to the identification of a yellow pigmentation mutant, gyl, that displayed significantly decreased chlorophyll(Chl) content and abnormal chloroplast development. Sequence analysis showed that gyl is allelic to Minn Gold, where a different single nucleotide polymorphism variation in the Mg-chelatase subunit gene(ChlI1a) results in golden yellow leaves. A cleaved amplified polymorphic sequence marker was developed and may be applied to marker-assisted selection for the golden yellow phenotype in soybean breeding. We show that the newly developed soybean EMS mutant population has potential for functional genomics research and genetic improvement in soybean.Zhongfeng Li Lingxue Jiang Yansong Ma Zhongyan Wei Huilong Hong Zhangxiong Liu Jinhui Lei Ying Liu Rongxia Guan Yong Guo Longguo Jin Lijuan Zhang Yinghui Li Yulong Ren Wei He Ming Liu Nang Myint Phyu Sin Htwe Lin Liu Bingfu Guo Jian Song Bing Tan Guifeng Liu Maiquan Li Xianli Zhang Bo Liu Xuehui Shi Sining Han Sunan Hua Fulai Zhou Lili Yu Yanfei Li Shuang Wang Jun Wang Ruzhen Chang Lijuan Qiu 2017Journal of Integrative Plant Biology2017,59,1:6
6High-Performance Aqueous Zinc-Ion Batteries Realized by MOF Materials显示文摘Rechargeable aqueous zinc-ion batteries(ZIB s) have been gaining increasing interest for large-scale energy storage applications due to their high safety,good rate capability,and low cost.However,the further development of ZIB s is impeded by two main challenges:Currently reported cathode materials usually suffer from rapid capacity fading or high toxicity,and meanwhile,unstable zinc stripping/plating on Zn anode seriously shortens the cycling life of ZIBs.In this paper,metal-organic framework(MOF) materials are proposed to simultaneously address these issues and realize high-performance ZIB s with Mn(BTC) MOF cathodes and ZIF-8-coated Zn(ZIF-8@Zn) anodes.Various MOF materials were synthesized,and Mn(BTC) MOF was found to exhibit the best Zn^2+-storage ability with a capacity of 112 mAh g^-1.Zn^2+ storage mechanism of the Mn(BTC) was carefully studied.Besides,ZIF-8@Zn anodes were prepared by coating ZIF-8 MOF material on Zn foils.Unique porous structure of the ZIF-8 coating guided uniform Zn stripping/plating on the surface of Zn anodes.As a result,the ZIF-8@Zn anodes exhibited stable Zn stripping/plating behaviors,with 8 times longer cycle life than bare Zn foils.Based on the above,high-performance aqueous ZIBs were constructed using the Mn(BTC) cathodes and the ZIF-8@Zn anodes,which displayed an excellent long-cycling stability without obvious capacity fading after 900 charge/discharge cycles.This work provides a new opportunity for high-performance energy storage system.Xuechao Pu Baozheng Jiang Xianli Wang Wenbao Liu Liubing Dong Feiyu Kang Chengjun Xu 2020Nano-Micro Letters2020,12,11:5
7cffdrs: an R package for the Canadian Forest Fire Danger Rating System显示文摘Introduction:The Canadian Forest Fire Danger Rating System(CFFDRS)is a globally known wildland fire risk assessment system,and two major components,the fire weather index system and the fire behavior prediction system,have been extensively used both nationally and internationally to aid operational wildland fire decision making.Methods:In this paper,we present an overview of an R package cffdrs,which is developed to calculate components of the CFFDRS,and highlight some of its functionality.In particular,we demonstrate how these functions could be used for large data analysis.Results and Discussion:With this cffdrs package,we provide a portal for not only a collection of R functions dealing with all available components in CFFDRS but also a platform for various additional developments that are useful for the understanding of fire occurrence and behavior.This is the first time that all relevant CFFDRS methods are incorporated into the same platform,which can be accessed by both the management and research communities.Xianli Wang B.Mike Wotton Alan S.Cantin Marc-AndréParisien Kerry Anderson Brett Moore Mike D.Flannigan 2017Ecological Processes2017,6,1:4
8Adiabatic Shear Mechanisms for the Hard Cutting Process显示文摘The most important consequence of adiabatic shear phenomenon is formation of sawtooth chip. Lots of scholars focused on the formation mechanism of sawtooth, and the research often depended on experimental approach. For the present, the mechanism of sawtooth chip formation still remains some ambiguous aspects. This study develops a combined numerical and experimental approach to get deeper understanding of sawtooth chip formation mechanism for Polycrystalline Cubic Boron Nitride(PCBN) tools orthogonal cutting hard steel GCr15. By adopting the Johnson-Cook material constitutive equations, the FEM simulation model established in this research effectively overcomes serious element distortions and cell singularity in high strain domain caused by large material deformation, and the adiabatic shear phenomenon is simulated successfully. Both the formation mechanism and process of sawtooth are simulated. Also, the change features regarding the cutting force as well as its effects on temperature are studied. More specifically, the contact of sawtooth formation frequency with cutting force fluctuation frequency is established. The cutting force and effect of cutting temperature on mechanism of adiabatic shear are investigated. Furthermore, the effects of the cutting condition on sawtooth chip formation are researched. The researching results show that cutting feed has the most important effect on sawtooth chip formation compared with cutting depth and speed. This research contributes a better understanding of mechanism, feature of chip formation in hard turning process, and supplies theoretical basis for the optimization of hard cutting process parameters.YUE Caixu WANG Bo LIU Xianli FENG Huize CAI Chunbin 2015Chinese Journal of Mechanical Engineering2015,28,3:4
9Substantial transition to clean household energy mix in rural China显示文摘The household energy mix has significant impacts on human health and climate,as it contributes greatly to many health-and climate-relevant air pollutants.Compared to the well-established urban energy statistical system,the rural household energy statistical system is incomplete and is often associated with high biases.Via a nationwide investigation,this study revealed high contributions to energy supply from coal and biomass fuels in the rural household energy sector,while electricity comprised∼20%.Stacking(the use of multiple sources of energy)is significant,and the average number of energy types was 2.8 per household.Compared to 2012,the consumption of biomass and coals in 2017 decreased by 45%and 12%,respectively,while the gas consumption amount increased by 204%.Increased gas and decreased coal consumptions were mainly in cooking,while decreased biomass was in both cooking(41%)and heating(59%).The time-sharing fraction of electricity and gases(E&G)for daily cooking grew,reaching 69%in 2017,but for space heating,traditional solid fuels were still dominant,with the national average shared fraction of E&G being only 20%.The non-uniform spatial distribution and the non-linear increase in the fraction of E&G indicated challenges to achieving universal access to modern cooking energy by 2030,particularly in less-developed rural and mountainous areas.In some non-typical heating zones,the increased share of E&G for heating was significant and largely driven by income growth,but in typical heating zones,the time-sharing fraction was<5%and was not significantly increased,except in areas with policy intervention.The intervention policy not only led to dramatic increases in the clean energy fraction for heating but also accelerated the clean cooking transition.Higher income,higher education,younger age,less energy/stove stacking and smaller family size positively impacted the clean energy transition.Guofeng Shen Rui Xiong Yanlin Tian Zhihan Luo Bahabaike Jiangtulu Wenjun Meng Wei Du Jing Meng Yuanchen Chen Bing Xue Bin Wang Yonghong Duan Jia Duo Fenggui Fan Lei Huang Tianzhen Ju Fenggui Liu Shunxin Li Xianli Liu Yungui Li Mu Wang Ying Nan Bo Pan Yanfang Pan Lizhi Wang Eddy Zeng Chao Zhan Yilin Chen Huizhong Shen Hefa Cheng Shu Tao 2022National Science Review2022,9,7:4
10Establishment and Characterization of a New Cell Line from the Kidney of Spotted Halibut Verasper variegates显示文摘A cell line,SHK,was derived from the kidney of spotted halibut Verasper variegates.The cell line was subculturedmore than 40 passages in minimum essential medium(MEM)supplemented with fetal bovine serum(FBS)and 10 ng ml-1basic fi-broblast growth factor(bFGF).Cell morphology from primary culture and subculture was observed continuously by microscopy.TheSHK cell line consisted predominantly of fibroblast-like cells.The cell line was able to grow between 20℃and 30℃with the optimum growth at 24℃and with a reduced growth between 12℃and 20℃.The growth rate of the cells increased as the proportion ofFBS increased from 10%to 20%at 28℃with optimum growth at the concentration of 20%.The doubling time of the cells was de-termined to be 44.8 h.Chromosome analysis revealed that 52%of the SHK cells maintained a normal diploid chromosome number(2n=46).The cells were successfully transfected with green fluorescent protein(GFP)reporter plasmids and the expression of GFPgene in the cells indicated the possible utility of the cells in gene expression studies.The cells were infected by lymphosystis diseasevirus(LCDV)and found to be susceptible to the virus in cytopathic effect(CPE)observation.The infection was confirmed by PCRand electron microscopy experiments,which proved the existence of the viral particles in the cytoplasm of the virus-infected cells.WANG Xianli CHEN Songlin SHA Zhenxia FAN Tingjun WANG Na 2010Journal of Ocean University of China2010,9,2:4
11Increased mtDNA copy number promotes cancer progression by enhancing mitochondrial oxidative phosphorylation in microsatellite-stable colorectal cancer显示文摘Colorectal cancer is one of the leading causes of cancer death worldwide.According to global genomic status,colorectal cancer can be classified into two main types:microsatellite-stable and microsatellite-instable tumors.Moreover,the two subtypes also exhibit different responses to chemotherapeutic agents through distinctive molecular mechanisms.Recently,mitochondrial DNA depletion has been shown to induce apoptotic resistance in microsatellite-instable colorectal cancer.However,the effects of altered mitochondrial DNA copy number on the progression of microsatellite-stable colorectal cancer,which accounts for the majority of colorectal cancer,remain unclear.In this study,we systematically investigated the functional role of altered mitochondrial DNA copy number in the survival and metastasis of microsatellite-stable colorectal cancer cells.Moreover,the underlying molecular mechanisms were also explored.Our results demonstrated that increased mitochondrial DNA copy number by forced mitochondrial transcription factor A expression significantly facilitated cell proliferation and inhibited apoptosis of microsatellitestable colorectal cancer cells both in vitro and in vivo.Moreover,we demonstrated that increased mitochondrial DNA copy number enhanced the metastasis of microsatellite-stable colorectal cancer cells.Mechanistically,the survival advantage conferred by increased mitochondrial DNA copy number was caused in large part by elevated mitochondrial oxidative phosphorylation.Furthermore,treatment with oligomycin significantly suppressed the survival and metastasis of microsatellite-stable colorectal cancer cells with increased mitochondrial DNA copy number.Our study provides evidence supporting a possible tumor-promoting role for mitochondrial DNA and uncovers the underlying mechanism,which suggests a potential novel therapeutic target for microsatellite-stable colorectal cancer.Xiacheng Sun Lei Zhan Yibing Chen Gang Wang Linjie He Qian Wang Feng Zhou Fang Yang Jin Wu Yousheng Wu Jinliang Xing Xianli He Qichao Huang 2018Signal Transduction and Targeted Therapy2018,3,1:3
12Radial vibration of a slit-type annular ultrasonic concentrator显示文摘The radial vibration characteristic of an annular ultrasonic concentrator with multislits is studied.Based on the electro-mechanical analogy and by introducing an area ratio coefficient,the radial vibrational equivalent circuit and the frequency equation of the concentrator are derived.The radial displacement amplitude magnification factor of it is obtained.By numerical calculating,the relationship between the radial displacement amplitude magnification factor,the resonance frequency of the concentrator at the first and second resonance and its radius ratio are investigated.Also,the relationship between the radial displacement amplitude magnification factor,the resonance frequency of the concentrator and the length,the angle and the number of the silts are analyzed.It is illustrated that a maximum of displacement amplitude magnification factor of the concentrator appears with the increase of the radius ratio,and the amplitude magnification factor increase as the length,the angle and the number of the silts increase,while the radial resonance frequency of the concentrator decreases as the length,the angle and the number of the silts increase.The theoretical resonance frequencies are in good agreement with that of the FEM simulations and measurement.LIU Shiqing GUI Fengli WANG Jiatao YANG Xianli LI Luhua 2015Chinese Journal of Acoustics2015,34,2:2
13The effect of enzymes on the in vitro degradation behavior of Mg alloy wires in simulated gastric fluid and intestinal fluid显示文摘With an upsurge of biodegradable metal implants,the research and application of Mg alloys in the gastrointestinal environment of the digestive tract have been of great interest.Digestive enzymes,mainly pepsin in the stomach and pancreatin in the small intestine,are widespread in the gastrointestinal tract,but their effect on the degradation of Mg alloys has not been well understood.In this study,we investigated the impacts of pepsin and pancreatin on the degradation of Mg-2Zn alloy wires.The results showed that the pepsin and pancreatin had completely different even the opposite effects on the degradation of Mg,although they both affected the degradation product layer.The degradation rate of Mg wire declined with the addition of pepsin in simulated gastric fluid(SGF)but rose with the addition of pancreatin in simulated intestinal fluid(SIF).The opposite trends in degradation rate also resulted in completely different degradation morphologies in wires surface,where the pitting corrosion in SGF was inhibited because of the physical barrier effect of pepsin adsorption.In contrast,the adsorption of pancreatin affected the integrity of magnesium hydrogen phosphate film,causing a relatively uneven degraded surface.These results may help us to understand the role of different digestive enzymes in the degradation of magnesium and facilitate the development and clinical application of magnesium alloy implanted devices for the digestive tract.Yue Zhang Jian Cao Xianli Wang Huan Liu Yi Shao Chenglin Chu Feng Xue Jing Bai 2022Bioactive Materials2022,7,1:2
14CO flux of soil respiration in natural recovering karst abandoned farmland in Southwest China显示文摘To estimate carbon sequestration potential in the karst area,soil respiration in a natural recovering karst abandoned farmland in Shawan,Puding,Guizhou,southwest China was continuously and automatically monitored for more than two years.The results show that the CO2flux of soil respiration(2.63±1.89 lmol m^-2s-^1)is higher in the karst area than in non-karst areas under similar conditions but that regional value(1.32 lmol m-2s-1)is lower because of larger rock fragment coverage(~50%).A the same time,the temperature sensitivity of soil respiration(Q10)in this study area is significantly higher than that of non-karst areas under similar conditions.Soil respiration has an obvious temporal variation,which is reflected in a significant exponential relationship between soil respiration and soil temperature,but the relationship between soil respiration and soil moisture is very complex.Especially soil respiration has an obvious spatial variation,which is likely affected by different diffusion or water-rock reaction processes.Yanwei Wang Weijun Luo Guangneng Zeng Hanling Yang Meifang Wang Yina Lyu Anyun Cheng Lin Zhang Xianli Cai Jia Chen Shijie Wang 2020Acta Geochimica2020,39,4:2
15Mitochondrial transcription factor A plays opposite roles in the initiation and progression of colitis-associated cancer显示文摘Background:Mitochondria are key regulators in cell proliferation and apoptosis.Alterations in mitochondrial function are closely associated with inflammation and tumorigenesis.This study aimed to investigate whether mitochondrial transcription factor A(TFAM),a key regulator of mitochondrial DNA transcription and replication,is involved in the initiation and progression of colitis-associated cancer(CAC).Methods:TFAM expression was examined in tissue samples of inflammatory bowel diseases(IBD)and CAC by immunohistochemistry.Intestinal epithelial cell(IEC)-specific TFAM-knockout mice(TFAM^(△IEC))and colorectal cancer(CRC)cells with TFAM knockdown or overexpression were used to evaluate the role of TFAMin colitis and the initiation and progression ofCAC.The underlying mechanisms of TFAMwere also explored by analyzingmitochondrial respiration function and biogenesis.Results:The expression of TFAM was downregulated in active IBD and negatively associated with the disease activity.The downregulation of TFAM in IECs was induced by interleukin-6 in a signal transducer and activator of transcription 3(STAT3)/miR-23b-dependent manner.In addition,TFAM knockout impaired IECturnover to promote dextran sulfate sodium(DSS)-induced colitis inmice.Of note,TFAMknockout increased the susceptibility of mice to azoxymethane/DSSinduced CAC and TFAM overexpression protected mice from intestinal inflammation and colitis-associated tumorigenesis.By contrast,TFAM expression was upregulated in CAC tissues and contributed to cell growth.Furthermore,it was demonstrated that β-catenin induced the upregulation of TFAM through c-Myc in CRC cells.Mechanistically,TFAMpromoted the proliferation of both IECs and CRC cells by increasing mitochondrial biogenesis and activity.Conclusions:TFAM plays a dual role in the initiation and progression of CAC,providing a novel understanding of CAC pathogenesis.Shirong Yang Xianli He Jing Zhao Dalin Wang Shanshan Guo Tian Gao Gang Wang Chao Jin Zeyu Yan Nan Wang Yongxing Wang Yilin Zhao Jinliang Xing Qichao Huang 2021Cancer Communications2021,41,8:2
16Controlling the lateral and vertical dimensions of Bi2Se3 nanoplates via seeded growth显示文摘nanostructures 的形态学的调整经常是一项令人满意却挑战性的任务。我们采用了播种生长方法并且导致了运动控制综合双性人 < 潜水艇 class= “ a-plus-plus ” > 2 Se < 潜水艇 class= “ a-plus-plus ” > 有可修改的形态学的 3 nanoplates。由操作先锋答案与注射泵在被注入种子答案的率,二个特殊生长模式能被认识到。与快注射,双性人的厚度<潜水艇class=“ a-plus-plus ”> 2 Se <潜水艇class=“ a-plus-plus ”>当边长度从 160 nm (种子)长大了到 12 m 时, 3 nanoplates 稍微从 7.5 nm (种子)增加了到 9.5 nm ,在播种生长的 6 个连续回合以后。与慢注射,厚度和边长度分别地在 6 轮生长以后同时增加了到 35 nm 和 6 m。这二个模式能被看作在原子免职和表面移植之间的一场比赛。产品出现了有趣,厚度依赖者拉曼性质。另外, NIR 透明,高度传导性、灵活的双性人<潜水艇class=“ a-plus-plus ”> 2 Se <潜水艇class=“ a-plus-plus ”> 3 有不同厚度的薄电影被同样综合的双性人的集会构造<潜水艇class=“ a-plus-plus ”> 2 Se <潜水艇class=“ a-plus-plus ”> 3 nanoplates 。这条途径能显著地与多样的形态学基于播种生长和运动控制支持万用的 nanostructures 的发展。Awei Zhuang Yuzhou Zhao Xianli Liu Mingrui Xu Youcheng Wang Unyong Jeong Xiaoping Wang Jie Zeng 2015Nano Research2015,8,1:1
17Deacetoxycephalosporin C synthase(expandase):Research progress and application potential显示文摘Cephalosporins play an indispensable role against bacterial infections.Deacetyloxycephalosporin C synthase(DAOCS),also called expandase,is a key enzyme in cephalosporin biosynthesis that epoxides penicillin to form the hexavalent thiazide ring of cephalosporin.DAOCS in fungus Acremonium chrysogenum was identified as a bifunctional enzyme with both ring expansion and hydroxylation,whereas two separate enzymes in bacteria catalyze these two reactions.In this review,we briefly summarize its source and function,improvement of the conversion rate of penicillin to deacetyloxycephalosporin C through enzyme modification,crystallography features,the prediction of the active site,and application perspective.Xiaofan Niu Jian Zhang Xianli Xue Depei Wang Lin Wang Qiang Gao 2021Synthetic and Systems Biotechnology2021,6,4:1
18Study on the effects of molar ratio of MgO and MgCI2 on the properties of magnesium cement straw board based on experiment 显示文摘WANG Xianli ZHANG Chunyang 2015Applied Mechanics and Materials2015,,:1
19Quantitative assessment of risk associated with dietary intake of mycotoxin ochratoxin A on the adult inhabitants in Shanghai city of P.R. China显示文摘Zheng Han Dongxia Nie Xianli Yang Jianhua Wang Shaojie Peng Aibo Wu 2013Food Control2013,,2:1
20Increased MMP-21 expression is associated with poor overall survival of patients with gastric cancer显示文摘Tao Wu Yi Li Jianguo Lu Qing Qiao Guoqiang Bao Nan Wang Xianli He Xilin Du 2013Medical Oncology2013,,1:1
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