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| 1 | Effect of scraping therapy on weightlifting ability显示文摘OBJECTIVE:To verify the effects of scraping therapy on the weightlifting ability by measuring the subjective sensation,and changes of biomarkers.METHODS:Five students,who have been trained for 3 years in a sport school in China were participated in this study.A course of scraping therapy was applied to intervene during the normal 7-week of weightlifting training programme.The ability of weightlifting,the scale of rating perceived exertion and serum biochemical markers were measured before and after the intervention.RESULTS:Scraping therapy caused a significant increase in weightlifting ability(P<0.05).The level of rating perceived exertion remained stable with the increase in the training volume.Immuno-globulinA was significantly increased(P<0.05),and creatine kinase and blood urea nitrogen were significantly decreased(P<0.05).No significant changes were observed in white blood cell,neutrophil,and testosterone.CONCLUSION:Scraping therapy may facilitate weightlifting ability mainly by decreasing weight sensation and improving serum biochemical parameters. | Xingze Wang Wichai Eungpinichpong Jinsheng Yang Uraiwan Chatchawan Saowanee Nakmareong Yingying Wang Xinyan Gao | 2014 | Journal of Traditional Chinese Medicine2014，34，1： | 11 |
| 2 | Trust Access Authentication in Vehicular Network Based on Blockchain显示文摘Data sharing and privacy securing present extensive opportunities and challenges in vehicular network.This paper introducestrust access authentication scheme’as a mechanism to achieve real-time monitoring and promote collaborative sharing for vehicles.Blockchain,which can provide secure authentication and protected privacy,is a crucial technology.However,traditional cloud computing performs poorly in supplying low-latency and fast-response services for moving vehicles.In this situation,edge computing enabled Blockchain network appeals to be a promising method,where moving vehicles can access storage or computing resource and get authenticated from Blockchain edge nodes directly.In this paper,a hierarchical architecture is proposed consist of vehicular network layer,Blockchain edge layer and Blockchain network layer.Through a authentication mechanism adopting digital signature algorithm,it achieves trusted authentication and ensures valid verification.Moreover,a caching scheme based on many-to-many matching is proposed to minimize average delivery delay of vehicles.Simulation results prove that the proposed caching scheme has a better performance than existing schemes based on central-ized model or edge caching strategy in terms of hit ratio and average delay. | Shaoyong Guo Xing Hu Ziqiang Zhou Xinyan Wang Feng Qi Lifang Gao | 2019 | China Communications2019，16，6： | 10 |
| 3 | Mechanism of acupuncture regulating visceral sensation and mobility显示文摘Chinese ancient medical scientists have long focused on the internal and external contacts between acupoints on the surface of the body and the viscera.The Miraculous Pivot(it is one of the earliest medical classics in China)stated,“Twelve regular channels belong to the zang-fu organs internally,and connect to the extremities and joints externally.”Traditional Chinese medicine considers acupoints as defined areas where the Qi of viscera and meridians are transfused.These include the reaction points of visceral diseases on the body surface as well as the acupuncture trigger points that promote the flow of Qi and blood,and regulate visceral function.Chinese ancient medical scientists classified the specificity of the main acupoints in the body based on the meridian doctrine,which has been instructing clinical application for about 2000 years.Laws on the domino effect of acupoints have mainly focused on conclusions to clinical experiences.Indications of some acupoints exceed the practical paradigm since the excessive extension occurred during theory derivation.The current research direction on acupuncture focuses on three aspects:the effectiveness of acupuncture and moxibustion;the relevances and associations between meridians and viscera;and the physical and chemical properties and relevant physical basis of acupoints.The relevance between meridians and viscera is the central theory in the meridian doctrine,and acupoints are regarded as an important link in the relationship between meridians and viscera.Specific relationships between acupoints and target organs exist.Stimulating different acupoints on the body surface can help deal with different diseases,especially visceral diseases.In addition,acupoints have a dual function of reflecting and treating visceral diseases.There is no systemic research available on acupoint specificity,despite current knowledge and clinical experiences,which results in a weak foundation for acupuncture theory.This study focuses on the relevance and associations between meridians and viscera.A summary of the mechanisms of acupuncture regulating visceral sensation and mobility and the specific relationships between acupoints and their target organs are presented in this review. | Peijing Rong Bing Zhu Yuqing Li Xinyan Gao Hui Ben Yanhua Li Liang Li Wei He Rupeng Liu Lingling Yu | 2011 | Frontiers of Medicine2011，5，2： | 8 |
| 4 | Recent progress in the numerical modeling for organic thin film solar cells显示文摘Device modeling is constructive in finding the dependency of devices efficiency on structure parameters and material properties. For the sake of looking into the physics mechanism of organic solar cells (OSCs), as well as predicting their maximum attainable efficiency, numerical modeling is widely utilized to simulate the behavior of OSCs. Although some indispensable parameters are neglected or hypothesized because of inexplicitness in simulation models for OSCs, numerical modeling can describe the kinetic process in OSCs intuitively. This paper summarizes the optical/electrical models in the BHJ solar cell, as well as addresses their corresponding development in recent years on the basis of device physics and its working principle. Applications of numerical modeling and comments on modeling results are summarized. Meanwhile, precision and open questions about every model are discussed. | ZHAO XinYan MI BaoXiu GAO ZhiQiang HUANG Wei | 2011 | Science China(Physics,Mechanics & Astronomy)2011，54，3： | 6 |
| 5 | Referred Somatic Hyperalgesia Mediates Cardiac Regulation by the Activation of Sympathetic Nerves in a Rat Model of Myocardial Ischemia显示文摘Myocardial ischemia(MI)causes somatic referred pain and sympathetic hyperactivity,and the role of sensory inputs from referred areas in cardiac function and sympathetic hyperactivity remain unclear.Here,in a rat model,we showed that MI not only led to referred mechanical hypersensitivity on the forelimbs and upper back,but also elicited sympathetic sprouting in the skin of the referred area and C8–T6 dorsal root ganglia,and increased cardiac sympathetic tone,indicating sympathetic-sensory coupling.Moreover,intensifying referred hyperalgesic inputs with noxious mechanical,thermal,and electro-stimulation(ES)of the forearm augmented sympathetic hyperactivity and regulated cardiac function,whereas deafferentation of the left brachial plexus diminished sympathoexcitation.Intradermal injection of the α_(2) adrenoceptor(α_(2)AR)antagonist yohimbine and agonist dexmedetomidine in the forearm attenuated the cardiac adjustment by ES.Overall,these findings suggest that sensory inputs from the referred pain area contribute to cardiac functional adjustment via peripheral α_(2)AR-mediated sympathetic-sensory coupling. | Xiang Cui Guang Sun Honglei Cao Qun Liu Kun Liu Shuya Wang Bing Zhu Xinyan Gao | 2022 | Neuroscience Bulletin2022，38，4： | 4 |
| 6 | Effect of QPQ nitriding time on wear and corrosion behavior of 45 carbon steel显示文摘 | Wei Cai Fanna Meng Xinyan Gao Jing Hu | 2012 | Applied Surface Science2012，，： | 3 |
| 7 | Cutaneous Hypersensitivity as an Indicator of Visceral Inflammation via C-Nociceptor Axon Bifurcation显示文摘Pain on the body surface can accompany disorders in the deep tissue or internal organs. However, the anatomical and physiological mechanisms are obscure.Here, we provided direct evidence of axon bifurcation in primary C-nociceptive neurons that innervate both the skin and a visceral organ. Double-labeled dorsal root ganglion(DRG) neurons and Evans blue extravasation were observed in 3 types of chemically-induced visceral inflammation(colitis, urocystitis, and acute gastritis) rat models.In the colitis model, mechanical hypersensitivity and spontaneous activity were recorded in vivo from doublelabeled C-nociceptive neurons in S1 or L6 DRGs. These neurons showed significantly enhanced responses to both somatic stimulation and colorectal distension. Our findings suggest that the branching of C-nociceptor axons contribute to cutaneous hypersensitivity in visceral inflammation. Cutaneous hypersensitivity on certain locations of the body surface might serve as an indicator of pathological conditions in the corresponding visceral organ. | Yehong Fang Shu Han Xiaoxue Li Yikuan Xie Bing Zhu Xinyan Gao Chao Ma | 2021 | Neuroscience Bulletin2021，37，1： | 3 |
| 8 | Separation and Purification of Thrombin-like Enzymes by Affinity Adsorbents显示文摘An affinity adsorbent, benzamidine Sepharose 4B, was used to separate and purify thrombin like enzymes. The p aminobenzamidine as a specific ligand was coupled to the matrix-Sepharose 4B. The recombinant thrombin like enzyme-defibrase was used as a model in order to evaluate the efficiency of this biospecific affinity adsorbent. The homogeneity of the enzyme preparation was comfirmed as one band on sodium dodecyl sulfate polyacrylamide gel electrophoresis. | 杨青 Xu Xiaoming Hu Xuejun Gao Xiaorong Dong Xinyan Su Zhiguo An Lijia | 2001 | High Technology Letters2001，7，4： | 2 |
| 9 | Effect of QPQ nitriding time on wear and corrosion behavior of 45 carbon steel显示文摘 | Wei Cai Fanna Meng Xinyan Gao etc | 2012 | Applied Surface Science2012，，261： | 1 |
| 10 | Whole-brain patterns of the presynaptic inputs and axonal projections of BDNF neurons in the paraventricular nucleus显示文摘Brain-derived neurotrophic factor (BDNF) plays a crucial role in human obesity. Yet, the neural circuitry supporting the BDNF-mediated control of energy homeostasis remains largely undefined. To map key regions that might provide inputs to or receive inputs from the paraventricular nucleus (PVN) BDNF neurons, a key type of cells in regulating feeding and thermogenesis, we used rabies virus-based transsynaptic labeling and adeno-associated virus based anterograde tracing techniques to reveal their whole-brain distributions. We found that dozens of brain regions provide dense inputs to or receive dense inputs from PVN BDNF neurons, including several known weight control regions and several novel regions that might be functionally important for the BDNF-mediated regulation of energy homeostasis.Interestingly, several regions show very dense reciprocal connections with PVN BDNF neurons, including the lateral septum, the preoptic area, the ventromedial hypothalamic nucleus, the paraventricular thalamic nucleus, the zona incerta, the lateral parabrachial nucleus, the subiculum, the raphe magnus nucleus, and the raphe pallidus nucleus. These strong anatomical connections might be indicative of important functional connections. Therefore, we provide an outline of potential neural circuitry mediated by PVN BDNF neurons, which might be helpful to resolve the complex obesity network. | Fang Luo Yuling Mu Cuicui Gao Yan Xiao Qian Zhou Yiqing Yang Xinyan Ni Wei L.Shen Jiajun Yang | 2019 | Journal of Genetics and Genomics2019，46，1： | 1 |
| 11 | Effect of QPQ nitriding time on wear and corrosion behavior of 45 carbon steel显示文摘 | Wei Cai Fanna Meng Xinyan Gao Jing Hu | 2012 | Applied Surface Science2012，，： | 1 |
| 12 | Prioritization of Veterinary Medicines in China’s Environment显示文摘 | Na Wang Xinyan Guo Zhengjun Shan Zanchang Wang Yi Jin Shixiang Gao | 2014 | Human and Ecological Risk Assessment: An International Journal2014，，5： | 1 |
| 13 | Effect of QPQ nitriding time on wear and corrosion behavior of 45 carbon steel显示文摘 | CAI Wei MENG Farina GAO Xinyan | 2012 | Applied Surface Science2012，261，15： | 1 |
| 14 | Effect of QPQ nitriding time on wear and corrosion behavior of 45 carbon steel显示文摘 | Cai Wei Meng Fanna Gao Xinyan | 2012 | Applied Surface Science2012，261，： | 1 |
| 15 | Construction and Characterization of a Novel Recombinant Single-Chain Variable Fragment Antibody against White Spot Syndrome Virus from Shrimp显示文摘 | Dai Heping Gao Hong Zhao Xinyan etal | 2003 | Journal of Immunological Methods2003，279，： | 1 |
| 16 | Numerical modeling of the failure process of the heterogeneous karst rock mass using the DDA-SPH method显示文摘The sanding process caused by karstification in dolomite creates a special sandy dolomite stratum,where the frequent catastrophic instability of the surrounding rock occurred during tunnel construction.In this study,the micro-origin and macro-performance of the sandy dolomite stratum are first discussed.Then,a numerical model based on the coupling method between the discontinuous deformation analysis and smoothed particle hydrodynamics is proposed to depict the heterogeneous dolomite formation with different sanding degrees.Following,the mechanical behaviors of the heterogeneous dolomite samples under uniaxial compression are studied after calibrating the numerical parameters with the two single materials sampled from the tunnel site respectively.Further,the instability disasters of the dolomite surrounding rock with different sanding degrees are reproduced,and the failure behaviors of tunnels are explained with respect to the stress distribution and plastic zone.The obtained results show that the rotation and dislocation of the remained dolomite block contribute to the unsmooth stress–strain curve and deterioration in uniaxial compressive strength.However,the block serves as the skeleton in the transmission of field stress in underground space,which improves the stability of the formation. | Jingyao Gao Guangqi Chen Zhijie Wang Liping Li Yasuhiro Mitani Changze Li Hongyun Fan Xinyan Peng Yifan Jiang | 2023 | Underground Space2023，，6： | 0 |
| 17 | Weakly Supervised Object Localization with Background Suppression Erasing for Art Authentication and Copyright Protection显示文摘The problem of art forgery and infringement is becoming increasingly prominent,since diverse self-media contents with all kinds of art pieces are released on the Internet every day.For art paintings,object detection and localization provide an efficient and ef-fective means of art authentication and copyright protection.However,the acquisition of a precise detector requires large amounts of ex-pensive pixel-level annotations.To alleviate this,we propose a novel weakly supervised object localization(WSOL)with background su-perposition erasing(BSE),which recognizes objects with inexpensive image-level labels.First,integrated adversarial erasing(IAE)for vanilla convolutional neural network(CNN)dropouts the most discriminative region by leveraging high-level semantic information.Second,a background suppression module(BSM)limits the activation area of the IAE to the object region through a self-guidance mechanism.Finally,in the inference phase,we utilize the refined importance map(RIM)of middle features to obtain class-agnostic loc-alization results.Extensive experiments are conducted on paintings,CUB-200-2011 and ILSVRC to validate the effectiveness of our BSE. | Chaojie Wu Mingyang Li Ying Gao Xinyan Xie Wing W.Y.Ng Ahmad Musyafa | 2024 | Machine Intelligence Research2024，21，1： | 0 |
| 18 | Cutaneous hypersensitivity as an indicator of visceral inflammation via C-nociceptor's axon bifurcation显示文摘Pain on the body surface might accompany disorders in the deep tissue or internal organ.However,the anatomical and physiological mechanism is obscure.Here,we provided direct evidences of axon bifurcation in primary C-nociceptive neurons that innervate both the skin and a visceral organ.Double-labeled dorsal root ganglion(RG)neurons and Evans blue extravasation were observed in 3 types of chemo-induced visceral inflammation(colitis,urocystitis and acute gastritis)rat models.In the rat model of colitis,mechanical hypersensitivity and spontaneous activities were recorded in vivo from double-labeled C nociceptive neurons in S1 or L6 DRG.These neurons showed significantly enhanced responses to both somatic stimulation and colorectal distension.Our findings suggest that axon branching of C-noceptors may contribute to cutaneous hypersensitivity in visceral inflammation.Cutaneous hypersensitivity on certain locations of body surface might serve as an indicator of pathological conditions in the corresponding visceral organ. | Fang Yehong Han Shu Li Xiaorue Xie Yikuan Zhu Bing Gao Xinyan Ma Chao | 2021 | 解剖学杂志2021，44，S01： | 0 |
| 19 | Therapeutic application of chick early amniotic fluid: effective rescue of acute myocardial ischemic injury by intravenous administration显示文摘Myocardial regeneration has been considered a promising option for the treatment of adult myocardial injuries.Previously,a chick early amniotic fluid(ceAF)preparation was shown to contain growth-related factors that pro-moted embryonic growth and cellular proliferation,though the nature of the components within ceAF were not fully defined.Here we tested whether this ceAF preparation is similarly effective in the promotion of myocardial regen-eration,which could provide an alternative therapeutic for intervening myocardial injury.In this study,a myocardial ischemic injury model was established in adult mice and pigs by multiple research entities,and we were able to show that ceAF can efficiently rescue damaged cardiac tissues and markedly improve cardiac function in both experimental models through intravenous administration.ceAF administration increased cell proliferation and improved angio-genesis,likely via down-regulation of Hippo-YAP signaling.Our data suggest that ceAF administration can effectively rescue ischemic heart injury,providing the key functional information for the further development of ceAF for use in attenuating myocardial injury. | Baiping Cui Yufan Zheng Xiang Gao Lihong Zhang Borui Li Jia Chen Xinyan Zhou Mengyuan Cai Wenrui Sun Yuting Zhang Keejong Chang Jiayi Xu Fuyin Zhu Yan Luo Tao Sun Jin Qian Ning Sun | 2022 | Cell Regeneration2022，11，1： | 0 |
| 20 | Cynomolgus-rhesus hybrid macaques serve as a platform for imprinting studies显示文摘Genomic imprinting can lead to allele-specific expression(ASE),where one allele is preferentially expressed more than the other.Perturbations in genomic imprinting or ASE genes have been widely observed across various neurological disorders,notably autism spectrum disorder(ASD).In this study,we crossed rhesus cynomolgus monkeys to produce hybrid monkeys and established a framework to evaluate their allele-specific gene expression patterns using the parental genomes as a reference.Our proof-of-concept analysis of the hybrid monkeys identified 353 genes with allele-biased expression in the brain,enabling us to determine the chromosomal locations of ASE clusters.Importantly,we confirmed a significant enrichment of ASE genes associated with neuropsychiatric disorders,including ASD,highlighting the potential of hybrid monkey models in advancing our understanding of genomic imprinting. | Zongyang Lu Jie Li Yong Lu Ling Li Wei Wang Chenchen Zhang Libing Xu Yanhong Nie Changshan Gao Xinyan Bian Zhen Liu Guang-Zhong Wang Qiang Sun | 2023 | The Innovation2023，4，3： | 0 |
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