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| 1 | Chinese herbal medicine reduces mortality in patients with severe and critical coronavirus disease 2019: a retrospective cohort study显示文摘This study aimed to evaluate the efficacy of Chinese herbal medicine(CHM)in patients with severe/critical coronavirus disease 2019(COVID-19).In this retrospective study,data were collected from 662 patients with severe/critical COVID-19 who were admitted to a designated hospital to treat patients with severe COVID-19 in Wuhan before March 20,2020.All patients were divided into an exposed group(CHM users)and a control group(non-users).After propensity score matching in a 1:1 ratio,156 CHM users were matched by propensity score to 156 non-users.No significant differences in seven baseline clinical variables were found between the two groups of patients.All-cause mortality was reported in 13 CHM users who died and 36 non-users who died.After multivariate adjustment,the mortality risk of CHM users was reduced by 82.2%(odds ratio 0.178,95%CI 0.076–0.418;P<0.001)compared with the non-users.Secondly,age(odds ratio 1.053,95%CI 1.023–1.084;P<0.001)and the proportion of severe/critical patients(odds ratio 0.063,95%CI 0.028–0.143;P<0.001)were the risk factors of mortality.These results show that the use of CHM may reduce the mortality of patients with severe/critical COVID-19. | Guohua Chen Wen Su Jiayao Yang Dan Luo Ping Xia Wen Jia Xiuyang Li Chuan Wang Suping Lang Qingbin Meng Ying Zhang Yuhe Ke An Fan Shuo Yang Yujiao Zheng Xuepeng Fan Jie Qiao Fengmei Lian Li Wei Xiaolin Tong | 2020 | Frontiers of Medicine2020，14，6： | 10 |
| 2 | The role played by traditional Chinese medicine in preventing and treating COVID-19 in China显示文摘Traditional Chinese medicine(TCM),an ancient system of alternative medicine,played an active role in the prevention and control of COVID-19 in China.It improved the clinical symptoms of patients,reduced the mortality rate,improved the recovery rate,and effectively relieved the operating pressure on the national medical system during critical conditions.In light of the current global pandemic,TCM-related measures might open up a new channel in the control of COVID-19 in other countries and regions.Here,we summarize the TCM-related measures that were widely used in China,including TCM guidelines,the Wuchang pattern,mobile cabin hospitals,integrated treatment of TCM and modern medicine for critical patients,and non-medicine therapy for convalescent patients,and describe how TCM effectively treated patients afflicted with the COVID-19.Effective TCM therapies could,therefore,be recommended and practiced based on the existing medical evidence from increased scientific studies. | Qingwei Li Han Wang Xiuyang Li Yujiao Zheng Yu Wei Pei Zhang Qiyou Ding Jiaran Lin Shuang Tang Yikun Zhao Linhua Zhao Xiaolin Tong | 2020 | Frontiers of Medicine2020，14，5： | 10 |
| 3 | Abrupt climate change of EastAsian Monsoon at 130 kaBP inferred from a high resolu-tion stalagmite δ^(18)O record显示文摘230Th ages and oxygen isotope data of a stalagmite from Shanbao Cave in Hubei Province characterize thEast Asian Monsoon precipitation from 133 to127 ka. Thdecadal-scale high-resolution δ18O record reveals a detailedtransitional process from the Penultimate Glaciation to thLast Interglaciation. As established with 230Th dates, the agof the Termination II is determined to be 129.5±1.0 kaBPwhich supports the Northern Hemisphere insolation as thtriggers for the ice-age cycles. In our δ18O record, the glacialinterglacial fluctuation reaches about 4‰, almost the samlevel as in other Asian Monsoon cave stalagmite δ18O recordThe transition of the glacial/interglacial period in our recordcan be recognized as four stepwise stages, among which, arapid rise of monsoon precipitation follows the stage o“Termination II pause”. The rapid rise is synchronous withthe abrupt change of global methane concentration, whichreflects that an increase in both Asian Monsoon precipitationand tropical wetland plays an important role in the globaclimate changes. | JIANG Xiuyang WANG Yongjin KONG Xinggong WU Jiangying SHAO Xiaohua XIA Zhifeng CHENG Hai | 2005 | Chinese Science Bulletin2005，50，23： | 9 |
| 4 | Stalagmite-inferred Holocene precipitation in northern Guizhou Province, China, and asynchronous termination of the Climatic Optimum in the Asian monsoon territory显示文摘An absolute-dated, bi-decadal-resolution, stalagmite oxygen-isotopic time series from Shigao Cave reveals the evolution of summer monsoon precipitation over the past 9.9 ka BP in northern Guizhou Province, Southwest China. The 18O-inferred climate conditions are divisible into three distinct stages: (1) a maximum humid era from 9.9-6.6 ka BP; (2) a gradual declining precipitation interval between 6.6-1.6 ka BP; and (3) a relatively low precipitation time window after 1.6 ka BP. Consistency of contemporaneous stalagmite Holocene 18O records between Shigao and other caves in the Indian and East Asian monsoon realms support the effect of primary orbital solar forcings on monsoonal precipitation. However, statistical analysis shows a significant spatial asynchroneity of the Holocene Optimum termination in the Asian monsoon territory. The Holocene Optimum ended at 7.2-7.4 ka BP in Oman, located in the Indian monsoon region, and at 5.6-5.8 ka BP in Central China, in the East Asian monsoon zone. In Southwest China, the termination occurred between these periods, at 6.6-7.0 ka BP, and was influenced by both monsoon systems. We propose that this spatially asynchronous ending of Holocene Optimum in Asia may be attributed to sea surface temperature changes in the western tropical Pacific, which is a primary moisture source for the East Asian monsoon. | JIANG XiuYang HE YaoQi SHEN ChuanChou KONG XingGong LI ZhiZhong CHANG YuWei | 2012 | Chinese Science Bulletin2012，57，7： | 6 |
| 5 | Interpretation of the Traditional Chinese Medicine portion of the diagnosis and treatment protocol for corona virus disease 2019(Trial Version 7)显示文摘The TCM protocol in the Diagnosis and Treatment Protocol for corona virus disease 2019(COVID-19)(Trial Version 7) has been updated from previous versions. The protocol was formulated under the direct leadership of the National Administration of Traditional Chinese Medicine, based on the experience of a panel of experts, supported by evidence from fever clinics and from the outcomes of emergency(EM) observation rooms and inpatients throughout China(especially in Wuhan, Hubei Province) in combination with the latest scientific research results and data. The present interpretation of the TCM protocol is based on an overall understanding of the revised content, and aims to guide and standardize its clinical application to provide a reference for clinicians. | Song Ping Zhao Linhua Li Xiuyang Su Jiansen Jiang Zhaoyuan Song Bin Liu Wenke Tang Shuang Lei Ye Ding Qiyou Yang Ze Lin Jiaran Wei Yu Tong Xiaolin | 2020 | Journal of Traditional Chinese Medicine2020，40，3： | 5 |
| 6 | Precise dating of East-Asian-Monsoon D/O events during 95―56 ka BP:Based on stalagmite data from Shanbao Cave at Shennongjia,China显示文摘Based on 23 U/Th analyses and 532 oxygen isotopic data, an averaged 80-a stalagmite oxygen isotopic composition series was established through 95 to 56 thousand years before present (ka BP) from two speleothems in Shanbao Cave, Shennongjia, central China. Shanbao Cave record (referred to as SB record) replicates well with Hulu Cave record, extending the characteristics of millennial oscillations in East-Asian-Summer-Monsoon (EASM) to the past 95 ka. The trend of the SB record generally follows mid-July solar insolation at 65°N, suggesting that mid-high northern latitude insolation, in the first or- der, controls changes of EASM intensity. Millennial oscillations of EASM recorded in the stalagmites are well related to the Greenland interstadials referred to as Dansgaard/Oeschger (D/O) events from 1 to 22, indicating that rapid ocean-atmosphere reorganization in North Atlantic has a remote effect in EASM. The well-dated D/O events by stalagmites probably provide an absolute calibration for chro- nologies of Greenland ice cores. The timings of D/O events in the SB record are different variously from those in Greenland ice cores. For D/O 19 and 20, the age offsets between the stalagmites' and the Greenland ice cores' record are significant, larger than the uncertainties of uranium-series dating. The two events in the SB record are younger than those in North GRIP time scale by 1―2 ka, and older than the counterparts in GISP2 by approximately 3―4 ka. A comparison between the SB and Brazil stalag- mite record shows an anti-phase relation in millennial-scale monsoon precipitation between the two localities. This supports a mode for the coupled ocean-atmosphere 'See-saw'. | XIA ZhiFeng KONG XingGong JIANG XiuYang CHENG Hai | 2007 | Science China Earth Sciences2007，50，2： | 4 |
| 7 | A local homogenization approach for simulating the reinforcement effect of the fully grouted bolt in deep underground openings显示文摘Fully grouted bolts are a key component of the support system for underground openings.Although considerable effort has been made in the simulation of the reinforcement effect of the fully grouted bolts on the rock masses surrounding underground openings,most of the work has limited significance since the structural element approach is used.This study proposes a local homogenization approach(L-H approach)that integrates elastoplastic mechanics,composite mechanics,and analytical approaches with numerical simulation to effectively simulate the reinforcement effect of the fully grouted bolt on deep surrounding rock masses.In the L-H approach,the representative volume of bolted rock mass(RVBRM)with a fully grouted bolt is established based on the original mesh model utilized in the rockbolt element approach.The RVBRM is a regular quadrangular prism with a cross-sectional size equal to the bolt spacing and a length equal to the bolt length.The RVBRM is homogenized by the L-H approach from a unidirectional bolt-reinforced composite into a homogeneous transversely isotropic medium whose mechanical properties are described by a new transversely isotropic elastoplastic model.The L-H parameters for the RVBRM are obtained using analytical approaches,composite mechanics,and known parameters of the rock mass and bolt.Using the L-H approach,the reinforcement effect of the fully grouted bolt on the bolted rock specimen and the surrounding rock mass in Jinping II Diversion Tunnel#2 with a depth greater than 2000 m is simulated.The results show that the predictions of the L-H approach are more in agreement with the physical model results of bolted rock specimen and provide a more realistic response of the bolted surrounding rock mass.The L-H approach demonstrates that fully grouted bolts with common bolt spacings and diameters substantially enhance the elastic modulus,shear strength,and tensile strength of the rock mass in the direction of the bolt axis. | Dingping Xu Xiuyang Liu Quan Jiang Shaojun Li Yangyi Zhou Shili Qiu Fei Yan Hong Zheng Xiang Huang | 2022 | International Journal of Mining Science and Technology2022，32，2： | 3 |
| 8 | Study on the Resistance of Pseudoperonospora cubensis to Cymoxanil显示文摘[Objective] The paper was to clarify the sensitivity and resistance of Pseudoperonospora cubensis to cymoxanil.[Method] A total of 69 strains were collected from 13 major cucumber producing areas in eight provinces and cities of Guangdong, Hubei, Jiangsu, Shandong, Beijing, Liaoning, Jilin and Heilongjiang from 2012 to 2016, and their sensitivity and resistance to cymoxanil was determined using leaf disc floating method.[Result] The EC50 of cymoxanil to P. cubensis were 0.006 8-0.134 1 μg/mL and the average EC50 was 0.062 4 μg/mL. The sensitivity of P. cubensis to cymoxanil presented a single-peak curve, which was approximately normal distribution, and no strains with decreased sensitivity were found. The average EC50 (0.062 4 μg/mL) could be used as the sensitivity baseline of P. cubensis to cymoxanil. Among the 69 strains, 16 were low-resistance strains, accounting for 23.19% of the total strains;53 were sensitive strains, accounting for 76.81%, which were dominant populations;and no medium-resistance and high resistance strains were found. The resistance of P. cubensis to cymoxanil ranged from 0.11 to 2.15 times, and the average resistant level was 1.00 times.[Conclusion] Cymoxanil showed strong inhibitory effect against P. cubensis. | Zhang Yanju He Ziwei Gao Jiyang Fu Lu Zhang Xingzhe Liu Qiyue Si Xiuyang | 2019 | Plant Diseases and Pests2019，10，3： | 1 |
| 9 | Enrichment and purification ofmadecassoside and asiaticoside from Centella asiatica ex- tracts with macroporous resins显示文摘 | Jia Guangtao Lu Xiuyang | 2008 | Journal of Chromatog-raphy A2008，1193，12： | 1 |
| 10 | One-pot preparation of methyl le- vulinate from catalytic aleoholysis of cellulose in near-critical meth- anol显示文摘 | Wu Xiaoyu Fu Jie Lu Xiuyang | 2012 | Carbohydrate Research2012，358，： | 1 |
| 11 | Enrichment and purification of made-cassoside and asiaticoside from Centella asiatica extracts with macroporous resins显示文摘 | Jia Guangtao Lu Xiuyang | 2008 | J Chromatogr A2008，1193，： | 1 |
| 12 | Analysis of Tissue-Specific Region in Sericin 1 Gene Promoter of Bombyx Mori 显示文摘 | Yan liu lian Yu Xiuyang Guo | 2006 | BBRC2006，342，： | 1 |
| 13 | Adaptive knot placement using a GMM-based continuous optimizationalgorithm in B-spline curve approximation显示文摘 | Zhao Xiuyang Zhang Caiming Yang Bo Li Pingping | | 0，，06： | 1 |
| 14 | Millennial and orbital-scale changes in the East Asian monsoon over the past 224,000 years显示文摘 | Wang Yongjin Cheng Hai Edwards R L Kong Xinggong Shao Xiaohua Chen Shitao Wu Jiangying Jiang Xiuyang Wang Xianfeng An Zhisheng | | 0，，7182： | 1 |
| 15 | Pt/Solid-Base: A Predominant Catalyst for Glycerol Hydrogenolysis in a Base-Free Aqueous Solution显示文摘 | Zhenle Yuan Pei Wu Jing Gao Xiuyang Lu Zhaoyin Hou Xiaoming Zheng | 2009 | Catalysis Letters (-)2009，，1： | 1 |
| 16 | Enrichment and purification of madecassoside and asiaticoside from Centella asiatica extracts with macroporous resins 显示文摘 | JIA Guangtao LU Xiuyang | 2008 | Journal of Chromatography A2008，1193，12： | 1 |
| 17 | IGA-based point cloud fitting using B-spline surfaces for reverse engineering 显示文摘 | ZHAO Xiuyang ZHANG Caiming XU Li | 2013 | Information Sciences2013，，245： | 1 |
| 18 | Productive infection of Autographa californica nucleopolyhedrovirus in silk- worm Bombyx mori strain Haoyue due to the absence of a host antiviral factor显示文摘 | Tingqing Guo Shengpeng Wang Xiuyang Guo | 2005 | Virology2005，341，： | 1 |
| 19 | Enrichment and purification of madeeassoside and asiatioside from Centella asiatica extracts with macroporous resins 显示文摘 | JIA Guangtao LU Xiuyang | 2008 | Journal of Chromatography A2008，1193，12： | 1 |
| 20 | Two-dimensional graphitic carbon nitride for membrane separation显示文摘Recent years,membrane separation technology has attracted significant research attention because of the efficient and environmentally friendly operation.The selection of suitable materials to improve the membrane selectivity,permeability and other properties has become a topic of vital research relevance.Two-dimensional(2D)materials,a novel family of multifunctional materials,are widely used in membrane separation due to their unique structure and properties.In this respect,as a novel 2D material,graphitic carbon nitride(g-C_(3)N_(4))have found specific attention in membrane separation.This study reviews the application of carbon nitride in gas separation membranes,pervaporation membranes,nanofiltration membranes,reverse osmosis membranes,ion exchange membranes and catalytic membranes,along with describing the separation mechanisms. | Tao Zheng Xiuyang Zou Meisheng Li Shouyong Zhou Yijiang Zhao Zhaoxiang Zhong | 2022 | Chinese Journal of Chemical Engineering2022，35，2： | 1 |
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