|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | STABC-IR:An air target intention recognition method based on bidirectional gated recurrent unit and conditional random field with space-time attention mechanism显示文摘The battlefield environment is changing rapidly,and fast and accurate identification of the tactical intention of enemy targets is an important condition for gaining a decision-making advantage.The current Intention Recognition(IR)method for air targets has shortcomings in temporality,interpretability and back-and-forth dependency of intentions.To address these problems,this paper designs a novel air target intention recognition method named STABC-IR,which is based on Bidirectional Gated Recurrent Unit(Bi GRU)and Conditional Random Field(CRF)with Space-Time Attention mechanism(STA).First,the problem of intention recognition of air targets is described and analyzed in detail.Then,a temporal network based on Bi GRU is constructed to achieve the temporal requirement.Subsequently,STA is proposed to focus on the key parts of the features and timing information to meet certain interpretability requirements while strengthening the timing requirements.Finally,an intention transformation network based on CRF is proposed to solve the back-and-forth dependency and transformation problem by jointly modeling the tactical intention of the target at each moment.The experimental results show that the recognition accuracy of the jointly trained STABC-IR model can reach 95.7%,which is higher than other latest intention recognition methods.STABC-IR solves the problem of intention transformation for the first time and considers both temporality and interpretability,which is important for improving the tactical intention recognition capability and has reference value for the construction of command and control auxiliary decision-making system. | Siyuan WANG Gang WANG Qiang FU Yafei SONG Jiayi LIU Sheng HE | 2023 | Chinese Journal of Aeronautics2023，36，3： | 4 |
| 2 | Sintilimab for relapsed/refractory extranodal NK/T cell lymphoma: a multicenter, single-arm, phase 2 trial (ORIENT-4)显示文摘This study(ORIENT-4)aimed to assess the efficacy and safety of sintilimab,a humanized anti-PD-1 antibody,in patients with relapsed/refractory extranodal NK/T cell lymphoma(r/r ENKTL).ORIENT-4 is a multicenter,single-arm,phase 2 clinical trial(NCT03228836).Patients with r/r ENKTL who failed to at least one asparaginase-based regimen were enrolled to receive sintilimab 200 mg intravenously every 3 weeks for up to 24 months.The primary endpoint was the objective response rate(ORR)based on Lugano 2014 criteria.Twenty-eight patients with r/r ENKTL were enrolled from August 31,2017 to February 7,2018.Twenty-one patients(75.0%,95%CI:55.1–89.3%)achieved an objective response.With a median follow-up of 30.4 months,the median overall survival(OS)was not reached.The 24-month OS rate was 78.6%(95%CI,58.4–89.8%).Most treatment-related adverse events(TRAEs)were grade 1–2(71.4%),and the most common TRAE was decreased lymphocyte count(42.9%).Serious adverse events(SAEs)occurred in 7(25.0%)patients,and no patient died of adverse events.Sintilimab is effective and well tolerated in patients with r/r ENKTL and could be a novel therapeutic approach for the control of ENKTL in patients. | Rong Tao Lei Fan Yongping Song Yu Hu Wei Zhang Yafei Wang Wei Xu Jianyong Li | 2021 | Signal Transduction and Targeted Therapy2021，6，11： | 4 |
| 3 | Multi-agent system application in accordance with game theory in bi-directional coordination network model显示文摘The multi-agent system is the optimal solution to complex intelligent problems. In accordance with the game theory, the concept of loyalty is introduced to analyze the relationship between agents' individual income and global benefits and build the logical architecture of the multi-agent system. Besides, to verify the feasibility of the method, the cyclic neural network is optimized, the bi-directional coordination network is built as the training network for deep learning, and specific training scenes are simulated as the training background. After a certain number of training iterations, the model can learn simple strategies autonomously. Also,as the training time increases, the complexity of learning strategies rises gradually. Strategies such as obstacle avoidance, firepower distribution and collaborative cover are adopted to demonstrate the achievability of the model. The model is verified to be realizable by the examples of obstacle avoidance, fire distribution and cooperative cover. Under the same resource background, the model exhibits better convergence than other deep learning training networks, and it is not easy to fall into the local endless loop.Furthermore, the ability of the learning strategy is stronger than that of the training model based on rules, which is of great practical values. | ZHANG Jie WANG Gang YUE Shaohua SONG Yafei LIU Jiayi YAO Xiaoqiang | 2020 | Journal of Systems Engineering and Electronics2020，31，2： | 3 |
| 4 | Balancing sub‐reaction activity to boost electrocatalytic urea synthesis using a metal‐free electrocatalyst显示文摘Electrocatalytic urea synthesis via coupling of nitrate with CO_(2)is considered as a promising alternative to the industrial urea synthetic process.However,the requirement of sub-reaction(NO_(3)RR and CO_(2)RR)activities for efficient urea synthesis is not clear and the related reaction mechanisms remain obscure.Here,the construction,breaking,and rebuilding of the sub-reaction activity balance would be accompanied by the corresponding regulation in urea synthesis,and the balance of sub-reaction activities was proven to play a vital role in efficient urea synthesis.With rational design,a urea yield rate of 610.6 mg h−1 gcat.−1 was realized on the N-doped carbon electrocatalyst,superior to that of noble-metal electrocatalysts.Based on the operando SRFTIR measurements,we proposed that urea synthesis arises from the coupling of^(*)NO and^(*)CO to generate the key intermediate of^(*)OCNO.This work provides new insights and guidelines into urea synthesis from the aspect of activity balance. | Chen Chen Shuang Li Xiaorong Zhu Shuowen Bo Kai Cheng Nihan He Mengyi Qiu Chao Xie Dezhong Song Youzhen Liu Wei Chen Yafei Li Qinghua Liu Conggang Li Shuangyin Wang | 2023 | Carbon Energy2023，5，10： | 2 |
| 5 | Simultaneous estimation of genetic linkage and preferential pairing factor for a triploid population with unphased markers显示文摘Triploids,recognized to occur more frequently in natural and experimental populations of many species than previously appreciated,display important economic and biological values.Despite this,however,linkage analysis for triploids has not been well explored.We develop a statistical model for estimating and testing the linkage between molecular markers in a triploid population derived from a tetraploid and diploid parent.The model incorporates one important meiotic feature of tetraploids by which more homologous chromosomes pair with a greater likelihood than less homologous chromosomes.By implementing the EM algorithm within the maximum likelihood framework,the model provides a procedure for simultaneous estimation of the linkage and preferential pairing factor.The model accommodates the segregating patterns of pseudotest markers and intercross markers with different amounts of informativeness.The utility of the model was validated through a real data analysis and simulation studies.The model provides a statistical tool for linkage analysis in a triploid population by taking into account meiotic behavior of tetraploids.Results from the model will help to shed light on the genetic diversity and origin of a polyploid population. | WANG JianXin DONG XiaoLi PANG XiaoMing LV YaFei YI HuaLin YANG XiaoXia WANG Zhong WU Song WU RongLing | 2012 | Chinese Science Bulletin2012，57，21： | 1 |
| 6 | Transient thermo-mechanical analysis for bimorph soft robot based on thermally responsive liquid crystal elastomers显示文摘Thermally responsive liquid crystal elastomers (LCEs) hold great promise in applications of soft robots and actuators because of the induced size and shape change with temperature. Experiments have successfully demonstrated that the LCE based bimorphs can be effective soft robots once integrated with soft sensors and thermal actuators. Here, we present an analytical transient thermo-mechanical model for a bimorph structure based soft robot, which consists of a strip of LCE and a thermal inert polymer actuated by an ultra-thin stretchable open-mesh shaped heater to mimic the unique locomotion behaviors of an inchworm. The coupled mechanical and thermal analysis based on the thermo-mechanical theory is carried out to underpin the transient bending behavior, and a systematic understanding is therefore achieved. The key analytical results reveal that the thickness and the modulus ratio of the LCE and the inert polymer layer dominate the transient bending deformation. The analytical results will not only render fundamental understanding of the actuation of bimorph structures, but also facilitate the rational design of soft robotics. | Yun CUI Yafei YIN Chengjun WANG K. SIM Yuhang LI Cunjiang YU Jizhou SONG | 2019 | Applied Mathematics and Mechanics(English Edition)2019，40，7： | 1 |
| 7 | Association of inflammatory and hemostatic markers with stroke and thromboembolic event in atrial fibrillation: a systematic review and meta-analysis显示文摘 | Na Wu Xinghua Chen Tongjian Cai Long Wu Ying Xiang Mengxuan Zhang Yafei Li Zhiyuan Song Li Zhong | 2014 | Canadian Journal of Cardiology2014，，： | 1 |
| 8 | Physical Activity,Sedentary Behavior,and the Risk of Cardiovascular Disease in Type 2 Diabetes Mellitus Patients:The MIDiab Study显示文摘The aim of this study was to explore the associations of moderate-to-vigorous-intensity physical activity(MVPA)time and sedentary(SED)time with a history of cardiovascular disease(CVD)and multifactorial(i.e.,blood pressure(BP),body mass index(BMI),low-density lipoprotein cholesterol(LDL-C),and glycated hemoglobin A1c(HbA1c))control status among type 2 diabetes mellitus(T2DM)patients in China.A cross-sectional analysis of 9152 people with type 2 diabetes from the Multifactorial Intervention on Type 2 Diabetes(MIDiab)study was performed.Patients were grouped according to their self-reported MVPA time(low,<150 min·week−1;moderate,150 to<450 min·week−1;high,≥450 min·week−1)and SED time(low,<4 h·d–1;moderate,4 to<8 h·d–1;high,≥8 h·d–1).Participants who self-reported a history of CVD were identified as having a CVD risk.Odds ratios(ORs)and 95%confidence intervals(CIs)of CVD risk and multifactorial control status associated with MVPA time and SED time were estimated using mixed-effect logistic regression models,adjusting for China’s geographical region characteristics.The participants had a mean±standard deviation(SD)age of(60.87±8.44)years,44.5%were women,and 25.1%had CVD.After adjustment for potential confounding factors,an inverse association between high MVPA time and CVD risk that was independent of SED time was found,whereas this association was not observed in the moderate-MVPA group.A higher MVPA time was more likely to have a positive effect on the control of BMI.Compared with the reference group(i.e.,those with MVPA time≥450 min·week−1 and SED time<4 h·d–1),CVD risk was higher in the low-MVPA group:The OR associated with an SED time<4 h·d–1 was 1.270(95%CI,1.040–1.553)and that associated with an SED time≥8 h·d–1 was 1.499(95%CI,1.149–1.955).We found that a high MVPA time(i.e.,≥450 min·week−1)was associated with lower odds of CVD risk regardless of SED time among patients with T2DM. | Yafei Wu Guijun Qin Guixia Wang Libin Liu Bing Chen Qingbo Guan Zhongshang Yuan Xu Hou Ling Gao Chao Xu Haiqing Zhang Xu Zhang Qiu Li Yongfeng Song Fei Jing Shizhan Ma Shanshan Shao Meng Zhao Qingling Guo Nanwei Tong Hongyan Zhao Xiaomin Xie Chao Liu Zhongyan Shan Zhifeng Cheng Xuefeng Yu Shulin Chen Tao Yang Yangang Wang Dongmei Li Zhaoli Yan Lixin Guo Qiuhe Ji Wenjuan Wang Jiajun Zhao | 2023 | Engineering2023，，1： | 1 |
| 9 | Network Security Situation Prediction Based on TCAN-BiGRU Optimized by SSA and IQPSO显示文摘The accuracy of historical situation values is required for traditional network security situation prediction(NSSP).There are discrepancies in the correlation and weighting of the various network security elements.To solve these problems,a combined prediction model based on the temporal convolution attention network(TCAN)and bi-directional gate recurrent unit(BiGRU)network is proposed,which is optimized by singular spectrum analysis(SSA)and improved quantum particle swarmoptimization algorithm(IQPSO).This model first decomposes and reconstructs network security situation data into a series of subsequences by SSA to remove the noise from the data.Furthermore,a prediction model of TCAN-BiGRU is established respectively for each subsequence.TCAN uses the TCN to extract features from the network security situation data and the improved channel attention mechanism(CAM)to extract important feature information from TCN.BiGRU learns the before-after status of situation data to extract more feature information from sequences for prediction.Besides,IQPSO is proposed to optimize the hyperparameters of BiGRU.Finally,the prediction results of the subsequence are superimposed to obtain the final predicted value.On the one hand,IQPSO compares with other optimization algorithms in the experiment,whose performance can find the optimum value of the benchmark function many times,showing that IQPSO performs better.On the other hand,the established prediction model compares with the traditional prediction methods through the simulation experiment,whose coefficient of determination is up to 0.999 on both sets,indicating that the combined prediction model established has higher prediction accuracy. | Junfeng Sun Chenghai Li Yafei Song Peng Ni Jian Wang | 2023 | Computer Systems Science & Engineering2023，47，10： | 0 |
| 10 | Photocatalytic Aerobic Oxysulfonylation of Alkynes to Access β-Keto Sulfones Catalyzed by OVs-N-Nb_(2)O_(5)显示文摘Herein,we report a novel heterogeneous photocatalyst for radical-mediated oxidative oxysulfonylation of alkynes toβ-keto sulfones under environmentally benign conditions.The oxygen vacancy-rich semiconductor Nb2O5(labeled as OVs-N-Nb_(2)O_(5))could efficiently catalyze a wide range of alkynes,especially for those bearing electron-deficient substituents or internal alkynes,to their correspondingβ-keto sulfones in good to high yields with good tolerance of diverse functional groups under visible-light illumination.The late-stage modification of steroidal compounds and synthesis of bioactive molecules were also achieved via this procedure,highlighting its potential for practical applications.Meanwhile,the photocatalyst OVs-N-Nb_(2)O_(5) showed outstanding catalytic stability for successive recycles without appreciable loss in activity and selectivity.The critical role of oxygen vacancies on improving reaction activity and selectivity was clearly disclosed via control experiments and theoretical calculation. | Tao Song Yinpan Zhang Chun Wang Yafei Li Yong Yang | 2022 | Chinese Journal of Chemistry2022，40，22： | 0 |
| 11 | A surrogate model for uncertainty quantification and global sensitivity analysis of nonlinear large-scale dome structures显示文摘Full-scale dome structures intrinsically have numerous sources of irreducible aleatoric uncertainties.A large-scale numerical simulation of the dome structure is required to quantify the effects of these sources on the dynamic performance of the structure using the finite element method(FEM).To reduce the heavy computational burden,a surrogate model of a dome structure was constructed to solve this problem.The dynamic global sensitivity of elastic and elastoplastic structures was analyzed in the uncertainty quantification framework using fully quantitative variance-and distribution-based methods through the surrogate model.The model considered the predominant sources of uncertainty that have a significant influence on the performance of the dome structure.The effects of the variables on the structural performance indicators were quantified using the sensitivity index values of the different performance states.Finally,the effects of the sample size and correlation function on the accuracy of the surrogate model as well as the effects of the surrogate accuracy and failure probability on the sensitivity index values are discussed.The results show that surrogate modeling has high computational efficiency and acceptable accuracy in the uncertainty quantification of large-scale structures subjected to earthquakes in comparison to the conventional FEM. | Huidong ZHANG Yafei SONG Xinqun ZHU Yaqiang ZHANG Hui WANG Yingjun GAO | 2023 | Frontiers of Structural and Civil Engineering2023，17，12： | 0 |
| 12 | Cryo-EM structures of human organic anion transporting polypeptide OATP1B1显示文摘Members of the solute carrier organic anion transporting polypeptide(OATPs)family function as transporters for a large variety of amphipathic organic anions including endogenous metabolites and clinical drugs,such as bile salts,steroids,thyroid hormones,statins,antibiotics,antivirals,and anticancer drugs.OATP1B1 plays a vital role in transporting such substances into the liver for hepatic clearance.FDA and EMA recommend conducting in vitro testing of drug–drug interactions(DDIs)involving OATP1B1.However,the structure and working mechanism of OATPs still remains elusive.In this study,we determined cryo-EM structures of human OATP1B1 bound with representative endogenous metabolites(bilirubin and estrone-3-sulfate),a clinical drug(simeprevir),and a fluorescent indicator(2′,7′-dichlorofluorescein),in both outward-and inward-open states.These structures reveal major and minor substrate binding pockets and conformational changes during transport.In combination with mutagenesis studies and molecular dynamics simulations,our work comprehensively elucidates the transport mechanism of OATP1B1 and provides the structural basis for DDI predictions involving OATP1B1,which will greatly promote our understanding of OATPs. | Ziyang Shan Xuemei Yang Huihui Liu Yafei Yuan Yuan Xiao Jing Nan Wei Zhang Wenqi Song Jufang Wang Feiwen Wei Yanqing Zhang | 2023 | Cell Research2023，33，12： | 0 |
| 13 | Self-adaptive combination method for temporal evidence based on negotiation strategy显示文摘In temporal information fusion,the information collected by sensors is obtained dynamically with the passage of time.Unlike the spatial information fusion,temporal fusion should be dynamic.Evidence theory has been applied to fuse temporal and spatial information;however,existing temporal fusion methods do not treat conflicting and non-conflicting evidence sources distinctively.Moreover,unlike spatial evidence sources,which are obtained simultaneously,temporal evidence sources cannot be evaluated simultaneously to obtain their degree of reliability.Thus,it is necessary to develop a method for temporal evidence combination.In this paper,a self-adaptive combination method for temporal evidence is proposed based on the negotiation strategy.In the proposed method,a set called an evidence set is constructed by the cumulative temporal fusion results of the previous moment,current moment,and future moment.The evidence set is evaluated as conflicting or non-conflicting according to the maximum power pignistic probability distance between each pair of evidence sources in the set.Then,temporal evidence sources are self-adaptively combined by different methods according to the degree of conflict.Numerical experiments were conducted to evaluate the performance of the proposed method.The results indicated that the proposed method is sufficiently effective and robust to support decision making. | Yafei SONG Jingwei ZHU Lei LEI Xiaodan WANG | 2020 | Science China(Information Sciences)2020，63，11： | 0 |
| 14 | The complete and fully-phased diploid genome of a male Han Chinese显示文摘Since the release of the complete human genome,the priority of human genomic study has now been shifting towards closing gaps in ethnic diversity.Here,we present a fully phased and well-annotated diploid human genome from a Han Chinese male individual(CN1),in which the assemblies of both haploids achieve the telomere-to-telomere(T2T)level.Comparison of this diploid genome with the CHM13 haploid T2T genome revealed significant variations in the centromere.Outside the centromere,we discovered 11,413 structural variations,including numerous novel ones.We also detected thousands of CN1 alleles that have accumulated high substitution rates and a few that have been under positive selection in the East Asian population.Further,we found that CN1 outperforms CHM13 as a reference genome in mapping and variant calling for the East Asian population owing to the distinct structural variants of the two references.Comparison of SNP calling for a large cohort of 8869 Chinese genomes using CN1 and CHM13 as reference respectively showed that the reference bias profoundly impacts rare SNP calling,with nearly 2 million rare SNPs miss-called with different reference genomes.Finally,applying the CN1 as a reference,we discovered 5.80 Mb and 4.21 Mb putative introgression sequences from Neanderthal and Denisovan,respectively,including many East Asian specific ones undetected using CHM13 as the reference.Our analyses reveal the advances of using CN1 as a reference for population genomic studies and paleo-genomic studies.This complete genome will serve as an alternative reference for future genomic studies on the East Asian population. | Chentao Yang Yang Zhou Yanni Song Dongya Wu Yan Zeng Lei Nie Panhong Liu Shilong Zhang Guangji Chen Jinjin Xu Hongling Zhou Long Zhou Xiaobo Qian Chenlu Liu Shangjin Tan Chengran Zhou Wei Dai Mengyang Xu Yanwei Qi Xiaobo Wang Lidong Guo Guangyi Fan Aijun Wang Yuan Deng Yong Zhang Jiazheng Jin Yunqiu He Chunxue Guo Guoji Guo Qing Zhou Xun Xu Huanming Yang Jian Wang Shuhua Xu Yafei Mao Xin Jin Jue Ruan Guojie Zhang | 2023 | Cell Research2023，33，10： | 0 |
| 15 | Effect of mushroom root fermentation broth on the umami taste and nutrients of Flammulina velutipes显示文摘As one of the most appealing edible mushrooms,the quality of Flammulina velutipes can be affected by the cultivation substrate,which has an impact on the mushroom umami taste and nutrients.In our study,the effect of mushroom root fermentation broth(MRFB)based substrate on umami taste and nutrients of F.velutipes were evaluated;four proportions of MRFB were conducted(CK 0%,E16.7%,E213.4%,E320.1%).Results indicated that MRFB was an effective nutrient supplement for mushroom cultivation substrate.E2 and E3 showed higher crude fiber,crude fat,and soluble protein.Compared to CK,the content of monosodium glutamate-like(MSG-like)amino acids,essential amino acids,total amino acids,and total 5′-nucleotides in E2 and E3 were higher.The equivalent umami concentration(EUC)values in E1,E2 and E3 were 1.70,2.43 and 1.56 times that of CK,respectively.Higher umami,saltness and sweetness taste values were found in E2.Thereby,it signified that better umami and richer nutrients were achieved by using substrate with proper volume of MRFB,especially,E2 with 13.4%of MRFB.Overall,better mushroom quality could be derived from the application of MRFB in cultivation.MRFB was a favorable nutrient supplement for F.velutipes cultivation substrate. | Zijian Wang Xiujing Bao Rongrong Xia Zhenshan Hou Yunting Li Yao Feng Yafei Wang Song Pan Heran Xu Zhuqing Huang Guang Xin | 2023 | Journal of Future Foods2023，3，1： | 0 |
| 16 | First Record of Cyclocarya from the Early Oligocene Qaidam Basin,North Tibet:Implications for the Paleogeography and Paleoecology显示文摘As the largest intermontane basin in the northeastern Tibetan Plateau(TP),the Qaidam Basin provides unique insight into paleoclimatic change and its relationship with global change and uplift on the TP.In this study,based on morphological comparison,fossil fruit of Cyclocarya from the Early Oligocene Shangganchaigou Formation in the Qaidam Basin is assigned as Cyclocarya cf.weylandii.The discovery of Cyclocarya cf.weylandii demonstrates the occurrence of Cyclocarya in the Oligocene sediment in Qaidam Basin.This is the first record of Cyclocarya fossil of Early Oligocene Age in China and indicates that Cyclocarya has existed on the northeastern TP since at least the Early Oligocene.The living analogues of the current fossil now lives in sub-tropical China,where the East Asian Monsoon is prevalent.Integrating the new fossils and previously reported fossil remains of plants and fishes,it can be inferred that the Early Oligocene Qaidam Basin was primarily influenced by westerly circulation and had a relatively warm and humid climate,which was in sharp contrast to the present-day climate in Qaidam Basin. | Yafei Hou Bowen Song Xiangchuan Li Fang Han Xu Zhang Kexin Zhang | 2024 | Journal of Earth Science2024，35，1： | 0 |
| 17 | Assessing non-point source pollution in an apple-dominant basin and associated best fertilizer management based on SWAT modeling显示文摘Investigating the impact of apple-dominated areas on nitrogen(N)and phosphorus(P)losses at a basin scale was essential for the sustainable development of apple industry in China.This study conducted a survey on fertilizer application and built a Soil and Water Assessment Tool(SWAT)model to quantita-tively analyze the N and P losses in the Qixia apple-dominated area.Additionally,the decreases in N and P losses through adjusting the fertilizer application modes were evaluated.Results showed that average N and P losses in the Wulong River Basin(WRB)were 44.4 and 0.365 kg ha^(-1)in 2011-2017,respectively,and apple orchards accounted for 733%and 51.4%of the total N and P losses in the basin.Under nine fertilizer scheduling scenarios,three fertilizer schedule scenarios,automatic fertilizer application(S-AUTO),'one shot'mode(S1),and regulated fertilizer application(S-BSD),had the lowest N and P losses in apple orchards.The decreases in N loss ranged from 20.6%to 26.1%at the subbasin scale and 14.8%-30.7%at the basin outlet when applying the S-AUTO,S1,and S-BSD fertilizer application modes in Qixia apple orchards and all apple orchards in the WRB.The reductions in P loss varied from 22.0%to 46.1%at the subbasin scale and 14.6%-25.6%at the basin outlet.In orchard-dominated basin,N and P losses can be effectively reduced by optimizing the orchard fertilizer scheduling strategies. | Yiwen Han Zhong Liu Yafei Chen Yingxuan Li Haipeng Liu Lianghong Song Yong Chen | 2023 | International Soil and Water Conservation Research2023，11，2： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员