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76篇 您的检索式:作者名="Yanli Ma"
    题名 作者 年代 出处 被引量
1Content and densities of soil organic carbon in urban soil in different function districts of Kaifeng显示文摘城市的土壤,与城市的发展一起形成,有土壤的唯一的性质器官的碳。根据地调查和实验室分析,玷污 Kaifeng 的器官的碳(SOC ) 城市被学习,并且结果证明 SOC 的特征在在城市的区域的功能区域之中是不同的不仅,而且在城市的区域和郊区之间。在表层土的 SOC 的顺序是工业区域 > 娱乐区域 > 交通区域 > 文化 / 教育的区域 > 居住 / 行政的区域。土壤的密度在表层土和侧面的器官的碳(SOCD ) 跟随了娱乐区域的订单 > 工业区域 > 交通区域 > 文化 / 教育的区域 > 居住 / 行政的区域,和文化 / 教育的区域 s > 交通区域 > 工业区域 > 娱乐区域 > 行政 / 居住的区域分别地。在表层土和侧面的 SOCD 从城市的区域沿着横断线减少了到郊区,城市的区域有 2.53 褶层在表层土和 1.56 褶层的更多的 SOCD 在侧面的更多的 SOCD 比郊区分别地。SOC 与深度减少了并且主要在 030 厘米的范围以内被散布。在城市的区域的 SOC 的变化在郊区是比那更复杂的。SUN Yanli MA Jianhua LI Can 2010Journal of Geographical Sciences2010,20,1:16
2Tracing the first hematopoietic stem cell generation in human embryo by single-cell RNA sequencing显示文摘Tracing the emergence of the first hematopoietic stem cells(HSCs)in human embryos,particularly the scarce and transient precursors thereof,is so far challenging,largely due to the technical limitations and the material rarity.Here,using single-cell RNA sequencing,we constructed the first genome-scale gene expression landscape covering the entire course of endothelial-to-HSC transition during human embryogenesis.The transcriptomically defined HSC-primed hemogenic endothelial cells(HECs)were captured at Carnegie stage(CS)12-14 in an unbiased way,showing an unambiguous feature of arterial endothelial cells(ECs)with the up-regulation of RUNX1,MYB and ANGPTL Importantly,subcategorizing CD34+CD45-ECs into a CD44+population strikingly enriched HECs by over 10-fold.We further mapped the developmental path from arterial ECs via HSC-primed HECs to hematopoietic stem progenitor cells,and revealed a distinct expression pattern of genes that were transiently over-represented upon the hemogenic fate choice of arterial ECs#including EMCN,PROCR and RUNX1T1.We also uncovered another temporally and molecularly distinct intra-embryonic HEC population,which was detected mainly at earlier CS 10 and lacked the arterial feature.Finally,we revealed the cellular components of the putative aortic niche and potential cellular interactions acting on the HSCprimed HECs.The cellular and molecular programs that underlie the generation of the first HSCs from HECs in human embryos,together with the ability to distinguish the HSC-primed HECs from others,will shed light on the strategies for the production of clinically useful HSCs from pluripotent stem cells.Yang Zeng Jian He Zhijie Bai Zongcheng Li Yandong Gong Chen Liu Yanli Ni Junjie Du Chunyu Ma Lihong Bian Yu Lan Bing Liu 2019Cell Research2019,29,11:14
3Osthole inhibits proliferation of human breast cancer cells by inducing cell cycle arrest and apoptosis显示文摘Recent studies have revealed that osthole,an active constituent isolated from the fruit of Cnidium monnieri(L.) Cusson,a traditional Chinese medicine,possesses anticancer activity.However,its effect on breast cancer cells so far has not been elucidated clearly.In the present study,we evaluated the effects of osthole on the proliferation,cell cycle and apoptosis of human breast cancer cells MDA-MB 435.We demonstrated that osthole is effective in inhibiting the proliferation of MDA-MB 435 cells,The mitochondrion-mediated apoptotic pathway was involved in apoptosis induced by osthole,as indicated by activation of caspase-9 and caspase-3 followed by PARP degradation.The mechanism underlying its effect on the induction of G1 phase arrest was due to the up-regulation of p53 and p21 and down-regulation of Cdk2 and cyclin D1 expression.Were observed taken together,these findings suggest that the anticancer efficacy of osthole is mediated via induction of cell cycle arrest and apoptosis in human breast cancer cells and osthole may be a potential chemotherapeutic agent against human breast cancer.Lintao Wang Yanyan Peng Kaikai Shi Haixiao Wang Jianlei Lu Yanli Li Changyan Ma 2015The Journal of Biomedical Research2015,29,2:12
4Status and development of high-power laser facilities at the NLHPLP显示文摘In this paper, we review the status of the multifunctional experimental platform at the National Laboratory of High Power Laser and Physics(NLHPLP). The platform, including the SG-II laser facility, SG-II 9th beam, SG-II upgrade(SG-II UP) facility, and SG-II 5 PW facility, is operational and available for interested scientists studying inertial confinement fusion(ICF) and a broad range of high-energy-density physics. These facilities can provide important experimental capabilities by combining different pulse widths of nanosecond, picosecond, and femtosecond scales. In addition, the SG-II UP facility, consisting of a single petawatt system and an eight-beam nanosecond system, is introduced including several laser technologies that have been developed to ensure the performance of the facility. Recent developments of the SG-II 5 PW facility are also presented.Jianqiang Zhu Jian Zhu Xuechun Li Baoqiang Zhu Weixin Ma Xingqiang Lu Wei Fan Zhigang Liu Shenlei Zhou Guang Xu Guowen Zhang Xinglong Xie Lin Yang Jiangfeng Wang Xiaoping Ouyang Li Wang Dawei Li Pengqian Yang Quantang Fan Mingying Sun Chong Liu Dean Liu Yanli Zhang Hua Tao Meizhi Sun Ping Zhu Bingyan Wang Zhaoyang Jiao Lei Ren Daizhong Liu Xiang Jiao Hongbiao Huang Zunqi Lin 2018High Power Laser Science and Engineering2018,6,4:8
5MiR-181a-5p inhibits cell proliferation and migration by targeting Kras in non-small cell lung cancer A549 cells显示文摘MicroRNAs 玩在 carcinogenesis 和肿瘤的重要角色进行。肺癌症是世界范围的癌症死亡的领先的原因。在这研究, miR-181a-5p 的功能在 non-small-cell 肺癌症(NSCLC ) 被调查。结果证明 miR-181a-5p 显著地在 NSCLC 纸巾和房间线被减少。有 miR-181a-5p 的 A549 房间 transfected 的增长和迁居模仿显著地被禁止。酶活动试金结果证明 Kras 的二个有约束力的地点能被 miR-181a-5p 直接指向。而且, Kras 由在 transcriptional 和翻译层次的 miR-181a-5p 是下面调整的。调停 SiRNA 的 Kras 下面规定能模仿 miR-181a-5p 的效果在 A549 模仿房间。我们的调查结果建议 miR-181a-5p 由部分指向 Kras 在肿瘤抑制起一个潜在的作用并且在 NSCLC 病人有潜在的治疗学的申请。Zhongliang Ma Xiang Qiu Detao Wang Yanli Li Bingjie Zhang Tianwei Yuan Jiali Wei Botao Zhao Xintai Zhao Jiatao LOU Yan Jin Youxin Jin 2015Acta Biochimica et Biophysica Sinica2015,47,8:8
6Downregulation of LINC01296 suppresses non-small-cell lung cancer via targeting miR-143-3p/ATG2B显示文摘The 5-year survival rate of lung cancer is one of the lowest among various malignant tumors.Long noncoding RNAs(lncRNAs),noncoding RNAs longer than 200 nucleotides,can function either as tumor suppressors or as oncogenes.The aim of this study is to investigate the function of lncRNA LINC01296 and its molecular mechanism in non-small-cell lung cancer(NSCLC).According to the Gene Expression Omnibus database,10 differentially expressed lncRNAs in NSCLC cells and patient tissues are upregulated.LINC01296 is the one with the most significant overexpression.Knockdown of LINC01296 inhibits the growth and migration,arrests the cell cycle,and promotes the apoptosis of NSCLC cells.Knocking down LINC01296 in vivo suppresses tumor growth and metastasis.LINC01296 also acts as the sponge of miR-143-3p.Lowering the expression of LINC01296 leads to decreased expression of autophagy-related 2B,ATG2B,a target gene of miR-143-3p.Moreover,downregulation of LINC01296 promotes paclitaxel sensitivity in NSCLC.These results demonstrated that the LINC01296/miR-143-3p/ATG2B axis is crucial in promoting the development of NSCLC and paclitaxel resistance.Our study may provide new ideas for the further research of clinical chemotherapy of NSCLC in the near future.Yanli Li Hui Zhang Jing Guo Wanqiu Li Xianyi Wang Caiyan Zhang Qiangling Sun Zhongliang Ma 2021Acta Biochimica et Biophysica Sinica2021,53,12:8
7Inhibition Effect of Water Injection on Afterburning of Rocket Motor Exhaust Plume显示文摘One of the most important characteristic signatures of the exhaust plume from rocket motor is the afterburning phenomenon,and the injected water into the plume could inhibit the afterburning.The calculation model for the gas-liquid multiphase flow field with chemical reaction in the plume is built.By inducing the energy source terms caused by the vaporization of liquid water,condensation of the vapor and chemical reaction in the energy equation,the gas-liquid multiphase flow field and the afterburning phenomenon are calculated in a coupling way.Mixture multiphase flow model is used to calculate the gas-liquid flow field,and the vaporization mechanism is used to investigate the water vaporization process.The temperature contours are obtained and accord well with the experimental photos.The mass fraction contours of primary species are obtained,which can indicate the extent of inhibition effect of water injection on the afterburning phenomenon in the plume.When water is injected into the plume,the region of afterburning reduces a lot,and temperature on the ground wall declines rapidly,which can decrease the ablation of the combustion gas to the launch ground.Jiang Yi Ma Yanli Wang Weichen Shao Liwu 2010Chinese Journal of Aeronautics2010,23,6:7
8Huge thick conglomerate movement induced by full thick longwall mining huge thick coal seam显示文摘A discrete elemental method was used to study the thickness of conglomerate layer in a full thick seam mining activities under the influence of the law, pointing out the thickness of the conglomerate at different seam mining, and during the destruction and instability of existing state of laws. At 21141 thick seam mining, the face toward the direction of separation between the thick layer of conglomerate rock and the next bit after reaching its maximum capacity due to pull from the bottom of the plastic zone, formed a stratified and hierarchical down collapse. The shape of caving area is a ''triangular block'', the length of the plastic zone and face advancement from the linear fit between the height of the plastic zone and the advancing face is a quadratic function of distance, while the top layer of thick gravel layer is the overall bending subsidence trend. Tilting the direction of the face, a thick gob of collapsed conglomerate layer is formed in the coal gob entity on both sides of the thick conglomerate at the top of the overall fracture morphology performance, thus forming a mutual extrusion of articulated block structure. The instability, separation and balance of the thick conglomerate layer in the hinged block stope stress leads to abnormal occurrence of rock burst induced by face as the major factor in the accident. This research reveals the form of stress distribution in the destroyed layer of the thick conglomerate rock, analyzes the stope law of coupling for the pressure burst behavior law for the mining work face, and the choice of preventive measures to provide a theoretical basis and implementation.Ma Liqiang Qiu xiaoxiang Dong Tao Zhang Jixiong Huang Yanli 2012International Journal of Mining Science and Technology2012,22,3:7
9A CRISPR evolutionary arms race: structural insights into viral anti-CRISPR/Cas responses显示文摘Jiuyu Wang Jun Ma Zhi Cheng Xu Meng Lilan You Min Wang Xinzheng Zhang Yanli Wang 2016Cell Research2016,26,10:6
10Surface quality of cold rolling aluminum strips under lubrication condition显示文摘The effects of oil film on the rolled surface,including surface roughness and topography,were investigated during cold rolling of aluminum strips.Various mineral oils with viscosities from 0.10 to 1.6 Pa.s were used to obtain different oil film thick- nesses.Results from experiment and calculation show that the thicker oil film protects the initial roughening surface so that it leads to an increase in roughness of the rolled surface,in particular when the surface roughness has the character of direction.The rolled surface roughness was determined byλ,which is the ratio of oil film thickness to the combined surface roughness.Whenλ>3,the rolled surface roughness increases rapidly with the increase in oil viscosity,whereas the surface roughening has already occurred whenλ<3,but the increase of the rolled surface roughness with increasing viscosity is not distinct.Jianlin Sun Wang Lu Yanli Ma Qingbing Shi Aihua Zhang Jian Li 2008Journal of University of Science and Technology Beijing2008,15,3:6
11Analysis of the supply-demand status of China's natural gas to 2020显示文摘The reserves,distribution,production and utilization of natural gas resources in China are introduced in this paper which leads a point of view that China's natural gas resources are relatively rich while distributed unevenly. The future production and consumption of China's natural gas are predicted using the Generalized Weng model and the Gray prediction model. The prediction suggests that with the increasing gas consumption China's natural gas production will not meet demand after 2010. In order to ease the supply-demand gap and realize rational development and utilization of China's natural gas resources,this paper puts forward some measures,such as using advanced technologies for natural gas development,establishing a long-distance pipeline network to rationalize the availability of natural gas across China and importing foreign natural gas and liquid natural gas(LNG) .MA Yifei LI Yanli 2010Petroleum Science2010,7,1:5
12Dissecting human embryonic skeletal stem cell ontogeny by single-cell transcriptomic and functional analyses显示文摘Human skeletal stem cells(SSCs)have been discovered in fetal and adult long bones.However,the spatiotemporal ontogeny of human embryonic SSCs during early skeletogenesis remains elusive.Here we map the transcriptional landscape of human limb buds and embryonic long bones at single-cell resolution to address this fundamental question.We found remarkable heterogeneity within human limb bud mesenchyme and epithelium,and aligned them along the proximal-distal and anterior-posterior axes using known marker genes.Osteo-chondrogenic progenitors first appeared in the core limb bud mesenchyme,which give rise to multiple populations of stem/progenitor cells in embryonic long bones undergoing endochondral ossification.Importantly,a perichondrial embryonic skeletal stem/progenitor cell(eSSPC)subset was identified,which could self-renew and generate the osteochondral lineage cells,but not adipocytes or hematopoietic stroma.eSSPCs are marked by the adhesion molecule CADM1 and highly enriched with FOXP1/2 transcriptional network.Interestingly,neural crest-derived cells with similar phenotypic markers and transcriptional networks were also found in the sagittal suture of human embryonic calvaria.Taken together,this study revealed the cellular heterogeneity and lineage hierarchy during human embryonic skeletogenesis,and identified distinct skeletal stem/progenitor cells that orchestrate endochondral and intramembranous ossification.Jian He Jing Yan Jianfang Wang Liangyu Zhao Qian Xin Yang Zeng Yuxi Sun Han Zhang Zhijie Bai Zongcheng Li Yanli Ni Yandong Gong Yunqiao Li Han He Zhilei Bian Yu Lan Chunyu Ma Lihong Bian Heng Zhu Bing Liu Rui Yue 2021Cell Research2021,31,7:5
13Vegetation and climate changes during the last 8660 cal.a BP in central Mongolia,based on a high-resolution pollen record from Lake Ugii Nuur显示文摘Based on modern pollen studies and reliable chronology of nine AMS 14C dates, a detailed history of vegetation and climate changes during the past 8660 cal. a BP was reconstructed by a high-resolution pollen record from Ugii Nuur in central Mongolia. Poaceae-steppe dominated the study area and the climate was mild and semi-humid before 7800 cal. a BP with a noticeable cool and humid interval at 8350―8250 cal. a BP. Xerophytic plant increased and the climate became warm and dry gradually since 7800 cal. a BP. From 6860 to 3170 cal. a BP, semi-desert steppe expanded, suggesting a prolonged warm and dry climate. Between 3170 and 2340 cal. a BP, regional forest steppe expanded whereas semi-desert steppe retreated, indicating the climate became cool and wet gradually and the humidity reached the maximum at the end of this stage. From 2340 to 1600 cal. a BP, a general cool and wet climate prevailed. And the climatic instability increased after 1600 cal. a BP. Review of regional pub-lished palaeoclimatic records implies that the mid-Holocene dry climate might have prevailed in vast areas from central Mongolia to arid areas of northwest China. Pollen-based climate reconstruction for UG04 core was well correlated with the result of climate model on Central Asia by Bush. In addition, several abrupt climatic events (cool and wet) were found and some could be broadly compared with the cool events in Atlantic.WANG Wei MA YuZhen FENG ZhaoDong MENG HongWei SANG YanLi ZHAI XinWei 2009Chinese Science Bulletin2009,54,9:5
14Mechanical properties and microstructure of TRIP steels produced using TSCR process显示文摘C-Si-Mn TRIP steels were produced using the thin slab casting and rolling (TSCR) process under simulation in laboratory. The results of tensile tests show that the yield strength,tensile strength,and the total elongation of the experimental TRIP steels are 430 MPa,610 MPa,and 28.4%,respectively. Optical microscopy,scanning electron microscopy (SEM),and transmission electron micros-copy (TEM) were employed to identify the microstructures of the TRIP steels. The final microstructures consist of ferrite,bainite,and retained austenite. The results of quantitative color metallography show that the fraction of the retained austenite is about 5.8%.Yinghui Zhang Yanli Ma Yonglin Kang Hao Yu 2006Journal of University of Science and Technology Beijing2006,13,5:4
15Differences of the oxidation process and secondary organic aerosol formation at low and high precursor concentrations显示文摘Current atmospheric quality models usually underestimate the level of ambient secondary organic aerosol(SOA), one of the possible reasons is that the precursors at different concentrations may undergo different oxidation processes and further affect SOA formation. Therefore, there is a need to perform more chamber studies to disclose the influence. In this work, SOA formation over a wide range of initial precursor concentrations(tens of ppb to hundreds of ppb levels) was investigated in a 30 m3 indoor smog chamber,and mainly through the analysis of multiple generations of VOCs detected from HR-To FPTRMS to expound the difference in the oxidation process between low and high precursor concentrations. Compared to high initial concentrations, gas-phase intermediates formed at low concentrations had a higher intensity by about one order of magnitude, and the lowvolatility compounds also had a higher formation potential due to the competition between semi-volatile intermediates and precursors with oxidants. In addition, the formed SOA was more oxidized with higher f44 value(0.14 ± 0.02) and more relevant to real atmosphere than that formed at high concentrations. This work should help to deeply understand SOA formation and improve the performance of air quality models for SOA simulation.Tianzeng Chen Yongchun Liu Biwu Chu Changgeng Liu Jun Liu Yanli Ge Qingxin Ma Jinzhu Ma Hong He 2019Journal of Environmental Sciences2019,31,5:4
16Poly(dimethyl siloxane)anti-corrosion coating with wide pH-responsive and self-healing performance based on core-shell nanofiber containers显示文摘In this research,core-shell electrospun fibers loaded with the shell of cellulose acetate and the core of oleic acid and alkyd varnish resin were synthesized and used within poly(dimethyl siloxane)(PDMS)to prepare self-healing and p H-responsive coatings for a steel substrate.The morphology of the electrospun fibers was characterized by scanning electron microscopy,transmission electron microscopy and confocal fluorescence microscopy.Thermo gravimetric analysis and Fourier transform infrared spectroscopy revealed that the self-healing agents were loaded successfully with a loading rate of 2.9%.The properties of the fiber-PDMS composite coating were characterized by water contact angle measurements,mechanical tests,electrochemical impedance spectroscopy,and scanning Kelvin probe.Results show that the maximum self-healing efficiencies of the fiber-PDMS coating in alkaline and acidic solution are 95.96%and 97.04%,respectively.The composition of the self-healing agents at the damaged part of the coating was verified by an infrared mapping test and using an energy dispersive spectrometer.In addition,the sandpaper abrasion test shows the hydrophobic effect of fiber-PDMS coating remains above 88.2%and decreases slightly through the addition of abrasion cycles.This research can pave the way for the industrial applications of p H-responsive self-healing coatings.Xiaohong Ji Wei Wang Xia Zhao Lifei Wang Fubin Ma Yanli Wang Jizhou Duan Baorong Hou 2022Journal of Materials Science & Technology2022,,6:4
17A Simple and Efficient Copper(Ⅱ) Complex as a Catalyst for N-Arylation of Imidazoles显示文摘四便宜并且 air-/moisture-stable pyrrolecarbaldiminato-Cu 建筑群 14 被综合并且评估了是为有芳基卤化物的咪唑的 N-arylation 的催化剂的一个新奇的班。许多芳基碘化物,溴化物和激活的芳基氯化物经历了结合咪唑,由催化剂支持了 4,在里面对没有由惰性的气体的保护的好收益中等。Yanli Jiao Nannan Yan Jianwei Xie Xiaowei Ma Ping Liu Bin Dai 2013Chinese Journal of Chemistry2013,31,2:3
18Clinical trials for the treatment of coronavirus disease 2019(COVID-19):A rapid response to urgent need显示文摘Emerging coronavirus disease 2019,known as COVID-19,is caused by the newly identified SARS-CoV-2 virus.Since the outbreak of COVID-19 in December 2019 in Wuhan(China),more than 70 thousand patients were affected.The disease resulted in 1,870 deaths by February 18,2020,according to the National Health Commission of People's Republic of China(http://www.nhc.gov.cn).Tengyue Zhang Yudi He Wenshuai Xu Aiping Ma Yanli Yang Kai-Feng Xu 2020Science China(Life Sciences)2020,63,5:3
19Total flavonoids from Ganshanbian (Herba Hyperici Attenuati) effect the expression of CaL-α1C and K_(ATP)-Kir6.1 mRNA of the myocardial cell membrane in myocardial ischemia-reperfusion arrhythmia rats显示文摘OBJECTIVE: To observe the impact of total flavonoids from Ganshanbian(Herba Hyperici Attenuati)on the expression of vascular smooth muscle membrane L-type calcium channel alpha1 C subunit(CaL-α1C) and ATP-sensitive K+channel(KATP)-Kir6.1mRNA, and explore the mechanisms of the antiarrhythmic effect of Ganshanbian(Herba Hyperici Attenuati)total flavonoids.METHODS: The treatment group was fed total flavonoids from Ganshanbian(Herba Hyperici Attenuati)for 7 days by gavage with 100 mg·kg﹣1·d﹣1.The blank control group and model control group were given the same amount of normal saline for 7 d.Arrhythmias were induced by performing a myocardial ischemia-reperfusion and electrocardiogram was observed. Reverse transcription-polymerase chain reaction was used to detect the expression of CaL-α1CandKATP-Kir6.1 mRNA in the myocardial cell membrane of all groups of rats. RESULTS: Total flavonoids from Ganshanbian(Herba Hyperici Attenuati) can delay the appearance of myocardial ischemia reperfusion arrhythmias,shorten the duration of myocardial ischemia reperfusion arrhythmias, reduce heart rate, reduce cell membrane expression of CaL-α1C mRNA and enhance the expression of KATP-Kir6.1 mRNAin myocardial ischemia-reperfusion arrhythmic rats.CONCLUSION: Total flavonoids from Ganshanbian(Herba Hyperici Attenuati) can alleviate arrhythmias by affecting the expression of L-type calcium channels and ATP-sensitiveK+ channels.Yuxuan Ma Yanli Wang Yanyu Gao Yin Fu Ji Li 2014Journal of Traditional Chinese Medicine2014,34,3:3
20Reconstructing the annual precipitation variation since 1899 based on tree-ring width in the western Hedong sandy land of Ningxia显示文摘Based on the analysis of the correlation between the tree-ring width of Pinus tabulaeformis and the climate factors in the western Hedong sandy land of Ningxia, a conversion equation between the annual precipitation and the tree-ring width since 1899 was reconstructed. The results of cross verification indicated that the conversion equation is stable and the reconstructed results are reliable. The result of reconstructed annual precipitation showed the remarkable fluctuation of precipitation and dry-to-wet variation before the 1940s. The smaller fluctuation and high frequent changes of precipitation occurred during the period of 1940s-1980s and after the 1980s the change trend of the precipitation became high periodic extent and low frequent. The study found that there were some coincidences with the climate change in Changling Mountains, Helan Mountains and the east of Qilian Mountains. The relatively dry periods in the beginning of 20th century, 1920s to 1930s, the end of the 20th century and 2004 to 2006 in the western Hedong sandy land of Ningxia accelerated the desertification, while the relatively humid period during the periods of the 1910s-1920s, 1930s-1940s and 1990s is favorable to prevent and control the desertification, and to weaken the climate warming and drying. The periods of annual precipitation variation in the western Hedong sandy land of Ningxia since 1899 are approximately 2-4 years, 5-7 years and 10 years.Wang, YaJun Gao, ShangYu Ma, YuZhen Lu, RuiJie Sang, YanLi Meng, HongWei 2010Journal of Arid Land2010,2,4:3
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