|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Petrographic characteristics and depositional environment of No.6 coal from Xiaoyugou Mine,Jungar Coalfield,China显示文摘This paper discussed the petrographic characteristics of No.6 coal from the Xiaoyugou mine,Jungar Coalfield,Ordos Basin,China.10 samples(7 coal,1 parting mudstone and 2 floor mudstone)were analysed by microscopical and geochemical methods.Four maceral compositions and several associated elements parameters were selected as indicators and corresponding diagrams were drawn to explicate the sedimentary environment.The results indicate that the maceral is dominated by vitrinite and minerals are mainly kaolinite in the No.6 coal.The sedimentary facies vary from barrier island system to tidal-flat which is a deposition process of water body shallowing and the coal-forming plants are herbs and woody plants formed in swamps. | Yanzhong Zhang Lin Xiao | 2014 | International Journal of Coal Science & Technology2014，1，4： | 20 |
| 2 | T cell–associated immunoregulation and antiviral effect of oxymatrine in hydrodynamic injection HBV mouse model显示文摘Although oxymatrine(OMT) has been shown to directly inhibit the replication of hepatitis B virus(HBV) in vitro, limited research has been done with this drug in vivo. In the present study, the antiviral effect of OMT was investigated in an immunocompetent mouse model of chronic HBV infection.The infection was achieved by tail vein injection of a large volume of DNA solution. OMT(2.2, 6.7 and20 mg/kg) was administered by daily intraperitoneal injection for 6 weeks. The efficacy of OMT was evaluated by the levels of HBV DNA, hepatitis B surface antigen(HBs Ag), hepatitis B e antigen(HBe Ag)and hepatitis B core antigen(HBc Ag). The immunoregulatory activity of OMT was evaluated by serum ELISA and flow cytometry. Results shows that OMT at 20 mg/kg inhibited HBV replication, and it was more efficient than entecavir(ETV) in the elimination of serum HBs Ag and intrahepatic HBc Ag. Inaddition, OMT accelerated the production of interferon-γ(IFN-γ) in a dose-dependent manner in CD4^+T cells. Our findings demonstrate the beneficial effects of OMT on the enhancement of immunological function and in the control of HBV antigens. The findings suggest this drug to be a good antiviral therapeutic candidate for the treatment of HBV infection. | Xiuxiu Sang Ruilin Wang Yanzhong Han Cong’en Zhang Honghui Shen Zhirui Yang Yin Xiong Huimin Liu Shijing Liu Ruisheng Li Ruichuang Yang Jiabo Wang Xuejun Wang Zhaofang Bai Xiaohe Xiao | 2017 | Acta Pharmaceutica Sinica B2017，7，3： | 20 |
| 3 | Reply to the Comment by Tan Mingxuan et al.(2017), on “A new Discovery of the Early Cretaceous Supercritical Hyperpycnal Flow Deposits on the Lingshan Island, East China”显示文摘We thank Tan Mingxuan et al.(2017)for their comments stimulated by our short paper in the recent Acta Geologica Sinica(English edition).We are grateful for the opportunity to expand on the model of the supercritical hyperpycnal flow deposits in the Beilaishi section on the Lingshan Island,and to explain why the model proposed by Tan Mingxuan et al.(2017)cannot explain the bulk | YANG Tian CAO Yingchang WANG Yanzhong | 2017 | Acta Geologica Sinica(English Edition)2017，91，6： | 19 |
| 4 | Status and Trends in Research on Deep-Water Gravity Flow Deposits显示文摘Deep-water gravity flows are one of the most important sediment transport mechanisms on Earth. After 60 years of study,significant achievements have been made in terms of classification schemes,genetic mechanisms,and depositional models of deep-water gravity flows. The research history of deep-water gravity flows can be divided into five stages: incipience of turbidity current theory; formation of turbidity current theory; development of deep-water gravity flow theory; improvement and perfection of deep-water gravity flow theory; and comprehensive development of deep-water gravity flow theory. Currently,three primary classification schemes based on the sediment support mechanism,the rheology and transportation process,and the integration of sediment support mechanisms,rheology,sedimentary characteristics,and flow state are commonly used.Different types of deep-water gravity flow events form different types of gravity flow deposits. Sediment slump retransportation mainly forms muddy debris flows,sandy debris flows,and surge-like turbidity currents. Resuspension of deposits by storms leads to quasi-steady hyperpycnal turbidity currents(hyperpycnal flows). Sustainable sediment supplies mainly generate muddy debris flows,sandy debris flows,and hyperpycnal flows. Deep-water fans,which are commonly controlled by debris flows and hyperpycnal flows,are triggered by sustainable sediment supply; in contrast,deep-water slope sedimentary deposits consist mainly of debris flows that are triggered by the retransportation of sediment slumps and deep-water fine-grained sedimentary deposits are derived primarily from finegrained hyperpycnal flows that are triggered by the resuspension of storm deposits. Harmonization of classification schemes,transformation between different types of gravity flow deposit,and monitoring and reproduction of the sedimentary processes of deep-water gravity flows as well as a source-to-sink approach to document the evolution and deposition of deep-water gravity flows are the most important research aspects for future studies of deep-water gravity flows study in the future. | YANG Tian CAO Yingchang WANG Yanzhong LI Ya ZHANG Shao Min | 2015 | Acta Geologica Sinica(English Edition)2015，89，2： | 18 |
| 5 | Characteristics and origin of abnormally high porosity zones in buried Paleogene clastic reservoirs in the Shengtuo area, Dongying Sag, East China显示文摘There are three abnormally high porosity zones developed in buried Paleogene nearshore subaqueous fan and sublacustrine fan clastic reservoirs at 2,800-3,200 m, 3,250-3,700 m and 3,900-4,400 m, respectively, within the Shengtuo area of the Dongying Sag. Here the porosity of reservoirs buried deeper than 4,000 m can still be greater than 20%. Investigation of these three abnormally high porosity(AHP) zones in the 3rd to 4th member of the Paleogene Shahejie Formation in the Shengtuo area was carried out with utilization of core observation, thin section identification, SEM observation, image analysis, core physical property testing and other technical methods. The results show that, the AHP zones in 2,800-3,200 m and 3,250-3,700 m are visible pores primary AHP zones dominated by significant primary intergranular pores(more than 50% of the total porosity), while secondary pores and micropores in authigenic clays may develop in some reservoirs. AHP reservoirs in the AHP zone of 3,900-4,400 m are dominated by micropores in matrix, visible pores are mainly grain dissolution pores but with low absolute content(< 1%), so this zone belongs to the micropores primary AHP zone. The genesis of the three AHP zones was studied to distinguish between porosity enhancement and porosity preservation. Our research shows that, in deeply buried clastic reservoirs in the Shengtuo area, mineral dissolution occurred in a relatively closed diagenetic system with high temperature and high salinity. Reservoir rocks underwent extensive feldspar dissolution, while detrital carbonate grains and carbonate cements show no evidence of extensive dissolution. Although significant feldspar dissolution pores developed, feldspar dissolution enhanced porosity only a little due to the precipitation of almost isovolumetric dissolution products in the nearby primary intergranular pores in forms of authigenic clays and quartz cements. Net enhanced porosity originating from feldspar dissolution is generally less than 0.25%. Thus, the subsurface dissolution has little impact on the mid-deep buried high porosity reservoirs. Reservoirs in braided channels of middle fans in sublacustrine fans and reservoirs in the middle-front of fan bodies of nearshore subaqueous fans provide the basis for the development of AHP zones. The shallow development of fluid overpressure and early hydrocarbon emplacement have effectively retarded compaction and carbonate cementation, so that the high porosity in the superficial layers is preserved in the mid-deep layers. These are the main controlling factors in the development of AHP zones. | Cao Yingchang Yuan Guanghui Li Xiaoyan Wang Yanzhong Xi Kelai Wang Xiaoming Jia Zhenzhen Yang Tian | 2014 | Petroleum Science2014，11，3： | 18 |
| 6 | Boron neutron capture therapy for malignant melanoma: first clinical case report in China显示文摘A phase Ⅰ/Ⅱ clinical trial for treating malignant melanoma by boron neutron capture therapy(BNCT) was designed to evaluate whether the world's first in-hospital neutron irradiator(IHNI) was qualified for BNCT. In this clinical trial planning to enroll 30 patients, the first case was treated on August 19, 2014. We present the protocol of this clinical trial, the treating procedure, and the clinical outcome of this first case. Only grade 2 acute radiation injury was observed during the first four weeks after BNCT and the injury healed after treatment. No late radiation injury was found during the 24-month follow-up. Based on positron emission tomography-computed tomography(PET/CT) scan, pathological analysis and gross examination, the patient showed a complete response to BNCT,indicating that BNCT is a potent therapy against malignant melanoma and IHNI has the potential to enable the delivery of BNCT in hospitals. | Zhong Yong Zewen Song Yongmao Zhou Tong Liu Zizhu Zhang Yanzhong Zhao Yang Chen Congjun Jin Xiang Chen Jianyun Lu Rui Han Pengzhou Li Xulong Sun Guohui Wang Guangqing Shi Shaihong Zhu | 2016 | Chinese Journal of Cancer Research2016，28，6： | 13 |
| 7 | Landscape of DILI-related adverse drug reaction in China Mainland显示文摘Drug-induced liver injury(DILI)is a type of bizarre adverse drug reaction(ADR)damaging liver(L-ADR)which may lead to substantial hospitalizations and mortality.Due to the general low incidence,detection of L-ADR remains an unsolved public health challenge.Therefore,we used the data of 6.673 million of ADR reports from January 1st,2012 to December 31st,2016 in China National ADR Monitoring System to establish a new database of L-ADR reports for future investigation.Results showed that totally 114,357 ADR reports were retrieved by keywords searching of liver-related injuries from the original heterogeneous system.By cleaning and standardizing the data fields by the dictionary of synonyms and English translation,we resulted 94,593 ADR records reported to liver injury and then created a new database ready for computer mining.The reporting status of L-ADR showed a persistent 1.62-fold change over the past five years.The national population-adjusted reporting numbers of L-ADR manifested an upward trend with age increasing and more evident in men.The annual reporting rate of L-ADR in age group over 80 years old strikingly exceeded the annual DILI incidence rate in general population,despite known underreporting situation in spontaneous ADR reporting system.The percentage of herbal and traditional medicines(H/TM)L-ADR reports in the whole number was 4.5%,while 80.60%of the H/TM reports were new findings.There was great geographical disparity of reported agents,i.e.more cardiovascular and antineoplastic agents were reported in higher socio-demographic index(SDI)regions and more antimicrobials,especially antitubercular agents,were reported in lower SDI regions.In conclusion,this study presented a large-scale,unbiased,unified,and computer-minable L-ADR database for further investigation.Age-,sex-and SDI-related risks of L-ADR incidence warrant to emphasize the precise pharmacovigilance policies within China or other regions in the world. | Jiabo Wang Haibo Song Feilin Ge Peng Xiong Jing Jing Tingting He Yuming Guo Zhuo Shi Chao Zhou Zixin Han Yanzhong Han Ming Niu Zhaofang Bai Guangbin Luo Chuanyong Shen Xiaohe Xiao | 2022 | Acta Pharmaceutica Sinica B2022，12，12： | 12 |
| 8 | Rationalizing phonon dispersion for lattice thermal conductivity of solids显示文摘Lattice thermal conductivity(κL) is one of the most fundamental properties of solids. The acoustic–elastic-wave assumption, proposed by Debye(Debye P. Ann Phys 1912; 344: 789–839), has led to linear phonon dispersion being the most common approximation for understanding phonon transport over the past century. Such an assumption does not take into account the effect of a periodic boundary condition on the phonon dispersion, originating from the nature of periodicity on atomic arrangements. Driven by modern demands on the thermal functionality of materials, with κLranging from ultra-low to ultra-high,any deviation from the Debye approximation in real materials becomes more and more significant. This work takes into account the periodic boundary condition, and therefore rationalizes the phonon dispersion to be more realistic. This significantly improves the precision for quickly predicting κLwithout any fitting parameters, as demonstrated in hundreds of materials, and offers a theoretical basis rationalizing κLto be lower than the minimum currently accepted based on the Debye dispersion. This work paves the way for designing solids with expected κLand particularly inspires the advancement of low-κLmaterials for thermal energy applications. | Zhiwei Chen Xinyue Zhang Siqi Lin Lidong Chen Yanzhong Pei | 2018 | National Science Review2018，5，6： | 12 |
| 9 | Glutamate and aspartate alleviate testicular/epididymal oxidative stress by supporting antioxidant enzymes and immune defense systems in boars显示文摘Several potential oxidative agents have damaging effects on mammalian reproductive systems.This study was conducted to investigate the effects of glutamate(Glu)and aspartate(Asp)supplementation on antioxidant enzymes and immune defense systems in the outer scrotum of boars injected with H2O2.A total of 24 healthy boars were randomly divided into 4 treatment groups:control(basal diet,saline-treated),H2O2(basal diet,H2O2-challenged outer scrotum(1 m L kg^–1 BW)),Glu(basal diet+2%Glu,H2O2-challenged),and Asp(basal diet+2%Asp,H2O2-challenged).Our results showed that both Glu and Asp supplementation improved testicular morphology and decreased the genital index in the H2O2-treated boars.Glu and Asp administration increased the antioxidant enzyme activities and affected the testicular inflammatory cytokine secretion but had no effect on sex hormone levels.Furthermore,the m RNA expression of CAT,Cu Zn SOD,and GPx4 was altered in the testes and epididymis of boars treated with Asp and Glu.Glu and Asp supplementation also modulated the expression of TGF-β1,IL-10,TNF-α,IL-6 and IL-1βin the testis and epididymis.These results indicate that dietary Glu and Asp supplementation might enhance antioxidant capacity and regulate the secretion and expression of inflammatory cytokines to protect the testes and epididymis of boars against oxidative stress. | Wenjie Tang Jian Wu Shunshun Jin Liuqin He Qinlu Lin Feijun Luo Xingguo He Yanzhong Feng Binsheng He Pingping Bing Tiejun Li Yulong Yin | 2020 | Science China(Life Sciences)2020，63，1： | 9 |
| 10 | Mechanism of diagenetic trap formation in nearshore subaqueous fans on steep rift lacustrine basin slopes—A case study from the Shahejie Formation on the north slope of the Minfeng Subsag, Bohai Basin, China显示文摘Diagenetic traps in conglomerate in nearshore subaqueous fans in the steep slope zones of rift basins have been important exploration targets for subtle reservoirs in eastern China. However, the mechanism of how those traps were formed is not clear, which inhibits further exploration for this type of reservoir. In order to solve the problem, we take as an example nearshore subaqueous fans in the upper part of the fourth member of the Shahejie Formation(Es4s) on the north slope of the Minfeng Subsag in the Dongying Sag. Combining different research methods, such as core observation, thin section examination, scanning electron microscope(SEM) observation, fluid-inclusion analysis, carbon and oxygen isotope analysis of carbonate cements, and analysis of core properties, we studied the genetic mechanisms of diagenetic traps on the basis of diagenetic environment evolution and diagenetic evolution sequence in different sub/micro-facies. Conglomerate in Es4 s in the north Minfeng Subsag experienced several periods of transition between alkaline and acidic environments as 'alkaline–acidic–alkaline–acidic–weak alkaline'. As a result, dissolution and cementation are also very complex, and the sequence is 'early pyrite cementation / siderite cementation / gypsum cementation / calcite and dolomite cementation——feldspar dissolution / quartz overgrowth——quartz dissolution / ferroan calcite cementation / ankerite cementation / lime-mud matrix recrystallization / feldspar overgrowth——carbonate dissolution / feldspar dissolution / quartz overgrowth / pyrite cementation'. The difference in sedimentary characteristics between different sub/micro-facies of nearshore subaqueous fans controls diagenetic characteristics. Inner fan conglomerates mainly experienced compaction and lime-mud matrix recrystallization, with weak dissolution, which led to a reduction in the porosity and permeability crucial to reservoir formation. Lime-mud matrix recrystallization results in a rapid decrease in porosity and permeability in inner fan conglomerates in middle-to-deep layers. Because acid dissolution reworks reservoirs and hydrocarbon filling inhibits cementation, reservoirs far from mudstone layers in middle fan braided channels develop a great number of primary pores and secondary pores, and are good enough to be effective reservoirs of hydrocarbon. With the increase of burial depth, both the decrease of porosity and permeability of inner fan conglomerates and the increase of the physical property difference between inner fans and middle fans enhance the quality of seals in middle-to-deep layers. As a result, inner fan conglomerates can be sealing layers in middle-to-deep buried layers. Reservoirs adjacent to mudstones in middle fan braided channels and reservoirs in middle fan interdistributaries experienced extensive cementation, and tight cemented crusts formed at both the top and bottom of conglomerates, which can then act as cap rocks. In conclusion, diagenetic traps in conglomerates of nearshore subaqueous fans could be developed with inner fan conglomerates as lateral or vertical sealing layers, tight carbonate crusts near mudstone layers in middle fan braided channels as well as lacustrine mudstones as cap rocks, and conglomerates far from mudstone layers in middle fan braided channels as reservoirs. Lime-mud matrix recrystallization of inner fan conglomerates and carbonate cementation of conglomerates adjacent to mudstone layers in middle fan braided channels took place from 32 Ma B.P. to 24.6 Ma B.P., thus the formation of diagenetic traps was from 32 Ma B.P. to 24.6 Ma B.P. and diagenetic traps have a better hydrocarbon sealing ability from 24 Ma B.P.. The sealing ability of inner fans gradually increases with the increase of burial depth and diagenetic traps buried more than 3,200 m have better seals. | Wang Yanzhong Cao Yingchang Ma Benben Liu Huimin Gao Yongjin Chen Lin | 2014 | Petroleum Science2014，11，4： | 9 |
| 11 | Effect of total aluminum concentration on the formation and transformation of nanosized Al_(13) and Al_(30) in hydrolytic polymeric aluminum aqueous solutions显示文摘Influence of total aluminum concentration (CAlT) on the generation and transformation of nanosized Al13 and Al30 in hydrolytic polyaluminum aqueous solutions was in-vestigated using high field 27Al NMR and time-developed Al-Ferron complex colorimetry. When prepared at the opti-mal basicity (B) of Al13 generation and 80℃, the Al13 species in polyaluminum solution tends to further polymerize and convert to Al30 and higher polymers when CAlT >0.2 mol·L?1, but Al13 does not convert to Al30 quantificationally, as the formation of Alu from Al13 and Al30 is accelerated in the same way. The conversion rate of Al13 is accelerated by the in-crease in CAlT. When CAlT >0.75 mol·L?1, Al13 content de-creases rapidly, and Al30 content increases continuously and becomes the dominant nanometer polynuclear aluminum species. Alm is one of prerequisites of Al13 conversion to Al30. When CAlT increases and B reduces, the polymerization rate between Al13 and Alm increases, and at the same time, the dissociation reaction rate of Al13 and Al30 by H+ also increases. The latter becomes the dominant reaction in polyaluminum solution with low B value, so Al30 decreases with the increas-ing CAlT. The hydrolytic polyaluminum solution with Al13 content beyond 80% can only be prepared under the condi-tion of CAlT<0.5 mol·L?1 and optimal B value. | CHEN Zhaoyang LIU Changjun LUAN Zhaokun ZHANG Zhongguo LI Yanzhong JIA Zhiping | 2005 | Chinese Science Bulletin2005，50，18： | 8 |
| 12 | Isolation and Characterization of a C-repeat Binding Transcription Factor from Maize显示文摘C-repeat binding proteins (CBFs) are a group of transcription factors that have been proven to be important for stress tolerance in plants. Many of these transcription factors transactivate the promoters of cold-regulated genes via binding to low temperature-or dehydration-responsive cis-elements, thus conferring plants cold acclimation. In the present study, we isolated a C-repeat binding transcription factor from maize using the yeast one-hybrid system with the C-repeat motif from the promoter of the Arabidopsis COR15a gene as bait. The isolated transcription factor is highly similar to the Arabidopsis CBF3 in their predicted amino acid sequences, and is therefore designated ZmCBF3. Point mutation analyses of the ZmCBF3-binding cis-element revealed (A/G)(C/T)CGAC as the core binding sequence. Expression analyses showed that ZmCBF3 was upregulated by both abscisic acid and low temperature, and was actively expressed during embryogenesis, suggesting that ZmCBF3 plays a role in stress response in maize. | Lei Wang Yanzhong Luo Lan Zhang Jun Zhao Zhiqiu Hu Yunliu Fan Chunyi Zhang | 2008 | Journal of Integrative Plant Biology2008，50，8： | 6 |
| 13 | Manipulation of Band Degeneracy and Lattice Strain for Extraordinary PbTe Thermoelectrics显示文摘Maximizing band degeneracy and minimizing phonon relaxation time are proven to be successful for advancing thermoelectrics.Alloying with monotellurides has been known to be an effective approach for converging the valence bands of PbTe for electronic improvements,while the lattice thermal conductivity of the materials remains available room for being further reduced.It is recently revealed that the broadening of phonon dispersion measures the strength of phonon scattering,and lattice dislocations are particularly effective sources for such broadening through lattice strain fluctuations.In this work,a fine control of MnTe and EuTe alloying enables a significant increase in density of electron states near the valence band edge of PbTe due to involvement of multiple transporting bands,while the creation of dense in-grain dislocations leads to an effective broadening in phonon dispersion for reduced phonon lifetime due to the large strain fluctuations of dislocations as confirmed by synchrotron X-ray diffraction.The synergy of both electronic and thermal improvements successfully leads the average thermoelectric figure of merit to be higher than that ever reported for p-type PbTe at working temperatures. | Yixuan Wu Pengfei Nan Zhiwei Chen Zezhu Zeng Siqi Lin Xinyue Zhang Hongliang Dong Zhiqiang Chen Hongkai Gu Wen Li Yue Chen Binghui Ge Yanzhong Pei | 2020 | Research2020，，1： | 6 |
| 14 | Effect of Dahuang Zhechong pills on long non-coding RNA growth arrest specific 5 in rat models of hepatic fibrosis显示文摘OBJECTIVE: To investigate the involvement of growth arrest specific 5(GAS5), a long non-coding RNA, in the anti-hepatic fibrosis process induced by Dahuang Zhechong pill(DHZCP) in rats.METHODS: Thirty adult rats were divided into three groups, including a control group, a CCl4-induced fibrosis group and a DHZCP-treated fibrosis group. Hematoxylin-eosin and Masson staining were used for histopathological study. Serum enzymes, cytokines and cell proliferation were assayed using commercially available kits. A GAS5 lenti-virus vector was constructed to further investigate the role of GAS5 in the anti-hepatic fibrosis effect of DHZCP in rats.RESULTS: Our results revealed that the proliferation of hepatic stellate cells cultured in serum derived from rats treated with DHZCP was significantly decreased, compared with cells treated with serum from the untreated rats. DHZCP alleviated the CCl4-induced hepatic fibrosis. Additionally, DHZCP can restore the expression of GAS5,which was significantly decreased in the CCl4-induced group, and markedly suppress the expression of p-p38 and p-Erk induced by CCl4, but not p-Jnk. Cell proliferation was significantly arrested when cells overexpressed GAS5. Thus,DHZCP can inhibit the expression of p-p38 and p-Erk, while GAS5 can only inhibit the expression of p-Erk.CONCLUSIONS: DHZCP can alleviate hepatic fibrosis by increasing the expression of GAS5 to suppress p-Erk and regulating other factors to inhibit p-p38. | Gong Zhenghua Deng Chaowen Xiang Tianxin Tao Lili Xiao Hongbo Peng Yanzhong Zheng Jie Hu Guoxin | 2018 | Journal of Traditional Chinese Medicine2018，38，2： | 6 |
| 15 | L-theanine inhibits nicotine-induced dependence via regulation of the nicotine acetylcholine receptor-dopamine reward pathway显示文摘In this study, the inhibitory effect of L-theanine, an amino acid derivative of tea, on the rewarding effects of nicotine and its underlying mechanisms of action were studied. We found that L-theanine inhibited the rewarding effects of nicotine in a con- ditioned place preference (CPP) model of the mouse and reduced the excitatory status induced by nicotine in SH-SY5Y cells to the same extent as the nicotine receptor inhibitor dihydro-beta-erythroidine (DH E). Further studies using high performance liquid chromatography, western blotting and immunofluorescence staining analyses showed that L-theanine significantly inhibited nicotine-induced tyrosine hydroxylase (TH) expression and dopamine production in the midbrain of mice. L-theanine treatment also reduced the upregulation of the 4, 2 and 7 nicotine acetylcholine receptor (nAChR) subunits induced by nico- tine in mouse brain regions that related to the dopamine reward pathway, thus decreasing the number of cells that could react to nicotine. In addition, L-theanine treatment inhibited nicotine-induced c-Fos expression in the reward circuit related areas of the mouse brain. Knockdown of c-Fos by siRNA inhibited the excitatory status of cells but not the upregulation of TH induced by nicotine in SH-SY5Y cells. Overall, the present study showed that L-theanine reduced the nicotine-induced reward effects via inhibition of the nAChR-dopamine reward pathway. These results may offer new therapeutic strategies for treatment of tobacco addiction. | DI XiaoJing YAN JingQi ZHAO Yan CHANG YanZhong ZHAO BaoLu | 2012 | Science China(Life Sciences)2012，55，12： | 6 |
| 16 | METHOD FOR PRECISE CALCULATION OF ROOT STRESS OF SPIRAL BEVEL GEARS显示文摘METHODFORPRECISECALCULATIONOFROOTSTRESSOFSPIRALBEVELGEARSMETHODFORPRECISECALCULATIONOFROOTSTRESSOFSPIRALBEVELGEARSChenLiangyu... | Chen Liangyu Wang Yanzhong Zheng Xijian E Zhongkai Cai Chunyuan(Northeastern University) | 1994 | Chinese Journal of Mechanical Engineering1994，7，4： | 5 |
| 17 | Iron metabolism in the mononuclear phagocyte system显示文摘身体铁动态平衡的维护要求铁新陈代谢的多重规章的机制的协作。单音的原子吞噬细胞系统(MPS,单核白血球,巨噬细胞,和他们的先锋房间镇静) 在铁动态平衡的维护是关键的。铁再循环被专业化巨噬细胞经由年老的红血球的吞没执行。巨噬细胞的铁店取决于恢复并且出口的铁的层次。然而,在巨噬细胞位于铁动态平衡下面的分子的机制糟糕被理解。描绘自然联系抵抗的巨噬细胞蛋白质 1 的功能和规定(Nramp1 ) 的最近的研究,二价的金属 transporter 1 (DMT1 ) ,连接 HLA 的 hemechromatosis 基因(HFE ) , ferroportin 1 (FPN1 ) ,并且 hepcidin 很快在 MPS 铁处理的分子的水平上正在扩展我们的知识。这些研究关于铁动态平衡和铁相关的疾病的分子的机制正在加深我们的理解。 | Weina Kong Xianglin Duan Zhenhua Shi Yanzhong Chang | 2008 | Progress in Natural Science:Materials International2008，18，10： | 5 |
| 18 | Assessing the benthic quality status of the Bohai Bay(China)with proposed modifications of M-AMBI显示文摘Multivariate AZTI's Marine Biotic Index(M-AMBI) was designed to indicate the ecological status of European coastal areas.Based upon samples collected from 2009 to 2012 in the Bohai Bay,we have tested the response of variations of M-AMBI,using biomass(M-BAMBI) in the calculations,with different transformations of the raw data.The results showed that the ecological quality of most areas in the study indicated by M-AMBI was from moderate to bad status with the worse status in the coastal areas,especially around the estuaries,harbors and outfalls,and better status in the offshore areas except the area close to oil platforms or disposal sites.Despite large variations in nature of the input data,all variations of M-AMBI gave similar spatial and temporal distribution patterns of the ecological status within the bay,and showed high correlation between them.The agreement of new ecological status obtained from all M-AMBI variations,which were calculated according to linear regression,was almost perfect.The benthic quality,assessed using different input data,could be related to human pressures in the bay,such as water discharges,land reclamation,dredged sediment and drilling cuts disposal sites.It seems that M-BAMBI were more effective than M-NABMI(M-AMBI calculated using abundance data) in indicating human pressures of the Bay.Finally,indices calculated with more severe transformations,such as presence/absence data,could not indicate the higher density of human pressures in the coastal areas of the north part of our study area,but those calculated using mild transformation(i.e.,square root) did. | CAI Wenqian BORJA Angel LIN Kuixuan ZHU Yanzhong ZHOU Juan LIU Lusan | 2015 | Acta Oceanologica Sinica2015，34，10： | 5 |
| 19 | Observation of parity-time symmetry in microwave photonics显示文摘Symmetry plays a crucial role in explorations of the laws of nature.Parity-time(PT)symmetry phenomena can lead to entirely real spectra in non-Hermitian systems,which attracts considerable attention in the fields of optics and electronics because these phenomena provide a new tool for the manipulation of oscillation modes and nonreciprocal signal transmission.A potential new field of application is microwave photonics,an interdisciplinary field in which the interaction between microwaves and optical signals is exploited.In this article,we report the experimental use of PT symmetry in an optoelectronic oscillator(OEO),a key microwave photonics system that can generate singlefrequency sinusoidal signals with high spectral purity.PT symmetry is theoretically analyzed and experimentally observed in an OEO with two mutually coupled active oscillation cavities via a precise manipulation of the interplay between gain and loss in the two oscillation cavities.Stable single-frequency microwave oscillation is achieved without using any optical/electrical filters for oscillation mode selection,which is an indispensable requirement in traditional OEOs.This observation opens new avenues for signal generation and processing based on the PT symmetry principle in microwave photonics. | Yanzhong Liu Tengfei Hao Wei Li Jose Capmany Ninghua Zhu Ming Li | 2018 | Light(Science & Applications)2018，7，1： | 5 |
| 20 | Ductile and ultrahigh-strength eutectic high-entropy alloys by large-volume 3D printing显示文摘1.Introduction Additive manufacturing or 3D printing outweighs conventional casting methods in the aspect of complex parts fabrication,which can realize one-step formation without the need of complicated cast dies.3D printing significantly promotes industrial production for making near-net shaped components.However,this promising technique is not always ideally applicable for metals and alloys.For example,titanium alloys prepared by 3D printing often suf-fer from poor plasticity,and usually require further complex heat treatment or hot isostatic pressing treatment,in order to remove internal stress and regulate plasticity and strength[1,2],which de-feats the original intention of employing additive manufacturing.One of the fundamental causes for such issues is the low fluidity of the alloys upon melting,leading to great chemical heterogeneity,high porosity content and residual stresses.This limitation hinders further design and fabrication of high-performance printable alloys from large scale production and application. | Yiping Lu Xiaoxiang Wu Zhenghong Fu Qiankun Yang Yong Zhang Qiming Liu Tianxin Li Yanzhong Tian Hua Tan Zhiming Li Tongmin Wang Tingju Li | 2022 | Journal of Materials Science & Technology2022，，31： | 4 |
您所在的机构暂未开通此部分的功能，请联系管理员