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| 1 | Spatiotemporal changes of cold surges in Inner Mongolia between 1960 and 2012显示文摘在这研究,我们在内部蒙古和包围区域从 121 个气象学的车站用每日的最小的温度数据在在 1960 和 2012 之间的内部蒙古和他们的可能的开车因素分析了冷巨浪的空间与时间的变化。这些数据被分析利用一个 piecewise 回归模型,一个 Sen+Mann-Kendall 模型,和关联分析。结果证明(1 ) 单个车站的冷巨浪的频率在学习时期期间在内部蒙古减少了,与 0.5 times/10a (2.4 ~ 1.2 times/10a ) 的一个线性趋势。在 1991 以前, 1.1 times/10a (3.3 ~ 2.5 times/10a ) 的一个重要减少趋势被检测,当 0.45 times/10a (4.4 ~ 4.2 times/10a ) 的一个增加的趋势在 1991 以后被发现时。在季节的规模上,在春天寒冷巨浪的趋势与年度价值一致,并且在冷巨浪的最明显的变化发生在春天期间。每月冷的巨浪频率显示了 bimodal 结构,并且 11 月见证冷巨浪的最高的发生。(2 ) 空间地,冷巨浪的高发生主要在内部蒙古的北、中央的部分被观察,与观察在的更高的出现比在中央部分北。内部十的特征也揭示了那高频率,分别地,低频率区域在 1960 和 1990 之间介绍了减少并且增加的趋势。在 1990 年代以后扩展的高频率区域,和展出高冷的巨浪频率的区域主要在 Tulihe, Xiaoergou,和 Xi Ujimqin 旗帜被散布。(3 ) 在年度规模上,冷巨浪被 AO, NAO, CA, APVII,和 CQ 统治。然而,在冷巨浪的驱动力的季节的差别被检测。冬季冷巨浪显著地与 AO, NAO,史, CA, TPI, APVII, CW,和 IZ 被相关,显示他们被多重因素引起。秋天冷巨浪被 CA 和 IM 主要影响,当春天寒冷巨浪显著地与 CA 和 APVII 被相关时。 | LIU Xianfeng | 2015 | Journal of Geographical Sciences2015，25，3： | 11 |
| 2 | Spatial and Temporal Evolution of Surface Subsidence in Tianjin from 2015 to 2020 Based on SBAS-InSAR Technology显示文摘Tianjin is one of the inland cities with the most severe cases of subsidence hazard in China.The majority of the existing studies have mainly focused on Beijing-Tianjin-Hebei,and little attention has been given to Tianjin.In addition,these existing studies are short-term investigations,lacking long-term monitoring of surface subsidence.In the present study,we use the Small Baseline Subset Interferometric Synthetic Aperture Radar(SBAS-InSAR)technique to monitor the subsidence process in Tianjin between 2015 and 2020 and reveal its spatial and temporal variation.We divided the 44-view Sentinel-1A image data into three periods to avoid the effect of temporal and spatial decoherence by extracting the surface deformation field in Tianjin.We finally verified the accuracy and reliability of the inversion results using second-order leveling data.Results showed that the correlation coefficient r between the two reached 0.89,and the root mean square error was 4.84 mm/y.Obvious subsidence funnels exist in Tianjin,mainly in the towns of Wangqingtuo and Shengfang.These subsidence funnels have a subsidence deformation rate of-136.2 mm/y and a maximum cumulative settlement of-346.3 mm within the study period.The subsidence area tends to extend to the southwest.The analysis of annual rainfall,groundwater resource extraction,spatial location distribution of industrial areas combined with SBAS-InSAR inversion results indicates that overextraction of groundwater resources is the main cause of land subsidence in the area.Therefore,strict control of groundwater extraction is the main approach to mitigate land subsidence effectively. | Lyu ZHOU Yizhan ZHAO Zilin ZHU Chao REN Fei YANG Ling HUANG Xin LI | 2022 | Journal of Geodesy and Geoinformation Science2022，5，1： | 8 |
| 3 | In vitro study of enhanced photodynamic cancer cell killing effect by nanometer-thick gold nanosheets显示文摘Photodynamic therapy(PDT)by near-infrared(NIR)irradiation is a promising technique for treating various cancers.Here,we reported the development of free-standing wafer-scale Au nanosheets(NSs)that exhibited an impressive PDT effect.The Au NSs were synthesized by ionic layer epitaxy at the air-water interface with a uniform thickness in the range from 2 to 8.5 nm.These Au NSs were found very effective in generating singlet oxygen under NIR irradiation.In vitro cellular study showed that the Au NSs had very low cytotoxicity and high PDT efficiency due to their uniform 2D morphology.Au NSs could kill cancer cells after 5 min NIR irradiation with little heat generation.This performance is comparable to using 10 times mass loading of Au nanoparticles(NPs).This work suggests that two-dimensional(2D)Au NSs could be a new type of biocompatible nanomaterial for PDT of cancer with an extraordinary photon conversion and cancer cell killing efficiency. | Ziyi Zhang Dalong Ni Fei Wang Xin Yin Shreya Goel Lazarus NGerman Yizhan Wang Jun Li Weibo Cai Xudong Wang | 2020 | Nano Research2020，13，12： | 2 |
| 4 | Regio- and (E)-Stereoselective Triborylation of Propargylic Carbonates显示文摘 | Zheng Yang Tao Cao Yulin Han Weilong Lin Qi Liu Yang Tang Yizhan Zhai Minqiang Jia Wanli Zhang Tonghao Zhu Shengming Ma | 2017 | Chinese Journal of Chemistry2017，35，8： | 2 |
| 5 | LncRNA NKILA suppresses airway hyper reactivity via interfering the facilitation of MUC5AC and MUC5B mediated by GALNT2显示文摘Glycosylation of mucins mediated by N-acetylgalactosaminyltransferases(GALNTs)is closely related to respiratory diseases such as asthma and chronic obstructive pulmonary disease(COPD).In addition,long non-coding RNAs(LncRNAs)participate in physiological and pathological processes through various epigenetic mechanisms.In this study,we found that a novel LncRNA named NKILA combined with multiple mucins and GALNTs potentially by several bioinformatics methods,and we used quantitative real-time PCR(RT-qPCR)to detect the expressions of NKILA,MUC5AC,MUC5B,and GALNT2 mRNA in 50 cases of asthma samples and 19 cases of normal samples,whose results showed that the expression of NKILA was significantly decreased in asthmatic samples,negatively correlated with the severity of asthma and the expressions of MUC5AC and MUC5B,while GALNT2 was significantly increased in asthmatic tissues,and positively correlated with the severity of asthma and the expressions of MUC5AC and MUC5B.In vitro,we used transient transfection technology to overexpress or interfere with NKILA and GALNT2 and then detected the expressions of MUC5AC and MUC5B via RT-qPCR and Western blot,which demonstrated GALNT2 can promote the expressions of MUC5AC and MUC5B protein,while NKILA could inhibit this effect.Furthermore,co-immunoprecipitation results showed that GALNT2 could bind to MUC5AC and MUC5B protein.RNA immunoprecipitation and RNA pull-down experiments showed that NKILA could bind to GALNT2.These evidences suggested that there are correlations among the expression of NKILA,GALNT2,MUC5AC,and MUC5B proteins in asthmatic patients.Mechanically,we concluded that NKILA can suppress the O-linked glycosylation of MUC5AC and MUC5B proteins by binding to GALNT2 and inhibit the expression of MUC5AC and MUC5B proteins.Our researches provided a potential therapeutic target for AHR. | YONGLI ZHANG YIZHAN CAO BO ZHU YANNI JIANG PENGCHONG LIANG | 2021 | BIOCELL2021，45，1： | 1 |
| 6 | Modulatory effects of one polysaccharide from Acanthopanax senticosus in alloxan-induced diabetic mice显示文摘 | Jianfang Fu Jufang Fu Yang Liu Ruiyu Li Bin Gao Nanyan Zhang Boliang Wang Yizhan Cao Kaoshan Guo Yanyang Tu | 2011 | Carbohydrate Polymers2011，，3： | 1 |
| 7 | Photo‐Responsive Self‐Assembly of an Azobenzene‐Ended Surfactant‐Encapsulated Polyoxometalate Complex for Modulating Catalytic Reactions显示文摘 | Yang Yang Liang Yue Haolong Li Eamonn Maher Yongguang Li Yizhan Wang Lixin Wu Vivian Wing‐Wah Yam | 2012 | Small2012，，20： | 1 |
| 8 | Iron-Catalyzed Aerobic Oxidation of Aldehydes: Single Component Catalyst and Mechanistic Studies显示文摘向在在空中把纯氧或氧的 1 atm 用作氧化剂和单个部件催化剂的催化数量的 MeCN 的羧基的酸的醛的氧气的氧化, Fe (没有 3)3 | Xingguo Jiang Yizhan Zhai Junyu Chen Yulin Han Zheng Yang Shengming Ma | 2018 | Chinese Journal of Chemistry2018，36，1： | 1 |
| 9 | Nanoparticle-Decorated Ultrathin La2O3 Nanosheets as an Effcient Electrocatalysis for Oxygen Evolution Reactions显示文摘Electrochemical catalysts for oxygen evolution reaction are a critical component for many renewable energy applications. To improve their catalytic kinetics and mass activity are essential for sustainable industrial applications. Here, we report a rare-earth metal-based oxide electrocatalyst comprised of ultrathin amorphous La2O3 nanosheets hybridized with uniform La2O3 nanoparticles(La2O3@NP-NS). Significantly improved OER performance is observed from the nanosheets with a nanometer-scale thickness. The as-synthesized 2.27-nm La2O3@NP-NS exhibits excellent catalytic kinetics with an overpotential of 310 mV at 10 m A cm^-2, a small Tafel slope of 43.1 mV dec^-1, and electrochemical impedance of 38 Ω. More importantly, due to the ultrasmall thickness, its mass activity, and turnover frequency reach as high as 6666.7 A g^-1 and 5.79 s^-1, respectively, at an overpotential of 310 mV. Such a high mass activity is more than three orders of magnitude higher than benchmark OER electrocatalysts, such as IrO2 and RuO2. This work presents a sustainable approach toward the development of highly e cient electrocatalysts with largely reduced mass loading of precious elements. | Guangyuan Yan Yizhan Wang Ziyi Zhang Yutao Dong Jingyu Wang Corey Carlos Pu Zhang Zhiqiang Cao Yanchao Mao Xudong Wang | 2020 | Nano-Micro Letters2020，12，4： | 1 |
| 10 | Damage Layer Evolution of a Breakwater Under Seawater Attack: Testing and Modeling显示文摘This paper presents experimental and theoretical methods to study the damage layer evolution of a breakwater made with concrete hollow squares in marine environment.Wetting time was directly related to the performance degradation of the breakwater by observation.The thickness of damage layer was detected by means of ultrasonic testing.Meanwhile,some samples drilled from concrete hollow squares were analyzed by SEM and XRD in order to illustrate the damage mechanism.Subsequently,a theoretical model containing wetting time ratio was established to simulate the damage layer evolution based on Fick’s second law,which could be suggested to predict the service life of concrete structures in marine environment. | Sheng Cang Yizhan Yang Jiankang Chen | 2020 | Acta Mechanica Solida Sinica2020，33，1： | 1 |
| 11 | MUTYH is a potential prognostic biomarker and correlates with immune infiltrates in hepatocellular carcinoma显示文摘Background:Hepatocellular carcinoma(HCC)is a leading cause of cancer-related death worldwide.The development of biomarkers for early detection and monitoring of HCC has not shown significant prog-ress.Meanwhile,the second adenomatous polyposis-related gene,MUTYH,which encodes a DNA gly-cosylase,has been observed in its contribution to oxidative DNA damage repair.Abnormal expression of MUTYH can reduce cell survival rate.Therefore,this study investigated the usefulness of MUTYH in diagnosing and prognosis HCC.Materials and methods:Using The Cancer Genome Atlas(TCGA)data,we analyzed the prognostic value of MUTYH in HCC.We used logistic regression,Wilcoxon signed-rank test,and KruskaleWallis test to examine MUTYH expression concerning clinical-pathologic characteristics.Univariate and multivariate Cox regression methods and Kaplan-Meier analysis were applied to determine the related prognostic factors of HCC.The enrichment analysis(GSEA)was used to determine the critical pathways associated with MUTYH.The single-sample gene set enrichment analysis(ssGSEA)was conducted to examine the correlation between MUTYH expression and cancer immune infiltration.Results:The higher expression of MUTYH in HCC patients was associated with a poorer overall survival rate and a shorter disease-specific survival rate.The Kyoto Encyclopedia of Genes and Genomes(KEGG)analysis showed that all differentially expressed genes(DEGs)between the high and low expression levels of MUTYH significantly enriched in the trace ligand-receptor interaction,cell cycle,oocyte meiosis,gap junction,and DNA replication.Group analysis revealed the signals of their open access.The neuron system,M phase,DNA repair,Rho GTPase effector,and cell cycle checkpoints were significantly enriched.ssGSEA showed a positive correlation between MUTYH expression and the infiltration levels of Th2 cells,NK cells,and T helper cells.Moreover,a negative correlation was found between MUTYH expression and the infiltration levels of dendritic cells(DCs)and cytotoxic cells.Conclusions:MUTYH expression levels were positively correlated with immune checkpoint gene expression levels in HCC tissues.The expression level of MUTYH was related to the prognosis of HCC and the immune infiltration of HCC. | Fan Yang Qinghai Lian Beibei Ni Xiusheng Qiu Yizhan He Xiaoguang Zou Fangping He Wenjie Chen | 2022 | Liver Research2022，6，4： | 0 |
| 12 | The mechanism to reform dynamic performance of an elastic wave-front in a piezoelectric semiconductor by the wave-carrier interaction induced from static biasing fields显示文摘The propagation of an elastic wave(EW)in a piezoelectric semiconductor(PSC)subjected to static biasing fields is investigated.It is found that there exist two coupling waves between electric field and charge carriers.One is stimulated by the action of the polarized electric field in the EW-front on charge carriers(EFC),and the other is stimulated by the action of initial electric field in biasing fields on dynamic carriers(IEC).Obviously,the latter is a man-made and tunable wave-carrier interaction.A careful study shows that IEC can play a leading role in remaking dynamic performance of the wave-front and an inter-medium role in transferring energy from biasing fields to EW-fronts.Hence,a method is proposed to reform the EW performance by biasing-fields:reforming the dispersivity of EW-fronts by promoting competition between IEC and EFC and inverting the dissipation by the IEC to transfer energy from biasing fields to EWfronts.The corresponding tuning laws on the phase-frequency characteristics of an EW show that the wave velocity can be regulated smaller than the pure EW velocity at a lowfrequency and larger than the pure piezoelectric wave velocity at a high-frequency.As for regulating the amplitude-frequency characteristics of the EW by the IEC,analyses show that EWs can obtain amplification only for those with relatively high vibration frequencies(small wave lengths).The studies will provide guidance for theoretical analysis of waves propagating in PSCs and practical application and design of piezotronic devices. | Wanli YANG Jinxi LIU Yizhan YANG Yuantai HU | 2023 | Applied Mathematics and Mechanics(English Edition)2023，44，3： | 0 |
| 13 | Thickness-Dependent Piezoelectric Property from Quasi-Two-Dimensional Zinc Oxide Nanosheets with Unit Cell Resolution显示文摘A quantitative understanding of the nanoscale piezoelectric property will unlock many application potentials of the electromechanical coupling phenomenon under quantum confinement.In this work,we present an atomic force microscopy-(AFM-)based approach to the quantification of the nanometer-scale piezoelectric property from single-crystalline zinc oxide nanosheets(NSs)with thicknesses ranging from 1 to 4 nm.By identifying the appropriate driving potential,we minimized the influences from electrostatic interactions and tip-sample coupling,and extrapolated the thickness-dependent piezoelectric coefficient(d_(33)).By averaging the measured d_(33) from NSs with the same number of unit cells in thickness,an intriguing tri-unit-cell relationship was observed.From NSs with 3n unit cell thickness(n=1,2,3),a bulk-like d_(33) at a value of~9 pm/V was obtained,whereas NSs with other thickness showed a~30%higher d_(33) of~12 pm/V.Quantification of d_(33) as a function of ZnO unit cell numbers offers a new experimental discovery toward nanoscale piezoelectricity from nonlayered materials that are piezoelectric in bulk. | Corey Carlos Yizhan Wang Jingyu Wang Jun Li Xudong Wang | 2021 | Research2021，，1： | 0 |
| 14 | Numerical Study on the Effect of the Manila Seismic Tsunami on the Guangdong Coast——The Nonlinear Effects of Tides and Tsunamis显示文摘The coupling numerical model between astronomical tide and tsunamis was built based on the data of the COMCOT model, which was verified by the Japan '3·11' tsunami. The tsunami source of the Manila seismic tsunami was designed and computed to analyze the risk of tsunami which will happen in the Guangdong coast. According to the results, the maximum quantity of water increasing and the time of the tsunami arriving at the Guangdong seacoast were calculated. The coupling simulation between astronomical tide and tsunamis has significant meaning for evaluating the risk and early-warning of tsunamis in the Guangdong coastal area. | CAO Yonggang LIU Changjian LIU Tongmu FENG Yanqing LIU Yuqiang LIAO Shizhi CHEN Yizhan | 2019 | Earthquake Research in China2019，33，1： | 0 |
| 15 | The Exponential Law Between Dwell Time and the Strength of PBX Substitute Material显示文摘Polymer-bonded sugars(PBSs)can be used as a substitute material for polymerbonded explosives(PBXs)due to their ability to simulate the mechanical properties of PBXs.In the process of pressing a PBS,the length of the dwell time has a significant impact on the mechanical properties of the PBS.This reinforcing effect is based on the residual pressure causing the binder to flow and gradually fill each defect.Through the use of Darcy5s principle of binder infiltration and viscoelastic theory,an exponential relationship between the compressive strength of PBS and the dwell time has been derived.From the experiments,it was found that the extreme forces that correspond to the compaction stage of the PBS samples with different dwell times were almost the same;this indicates that there is tolerance to damage during the compaction stage.The existence of the compaction stage is related to the brittleness of the PBS.The experimental results showed that as the dwell time increased,the rate of damage evolution of the specimen decreased. | Yizhan Yang Hangjie Lv Jiankang Chen | 2021 | Acta Mechanica Solida Sinica2021，34，2： | 0 |
| 16 | Effects of different doses of cadmium on secondary metabolites and gene expression in Artemisia annua L.显示文摘这研究瞄准位于 artemisinin 累积下面阐明的分子的机制由镉(Cd ) 导致了。Artemisia annua L 的生合成上的不同 Cd 集中(0, 20, 60,和 120 mol/L ) 的效果。被检验。中介和结束产品被 HPLC-ESI-MS/MS 分析确定。关键生合成酶的表示被 qRT-PCR 也决定。结果证明有为 3 天的 60 和 120 mol/L Cd 的处理的申请显著地改进了 artemisinic 酸, arteannuin B,和 artemisinin 的生合成。在 120 mol/L 的 artemisinic 酸, arteannuin B,和 artemisinin 的集中对待 Cd 的组分别地是比在控制组的那些高级 2.26, 102.08,和 33.63 倍的。在 60 mol/L 的 arteannuin B 和 artemisinin 的集中对待 Cd 的叶子分别地比在控制组的那些高 61.10 和 26.40 倍。HMGR, FPS,广告, CYP71AV1, DBR2, ALDH1,和 DXR 的相对表示层次在 120 mol/L 是起来调整的对待 Cd 的组因为在 3 天处理以后的 artemisinic 代谢物的增加的内容。因此, Cd 的适当剂量能增加在某个时间的代谢物指由的 artemisinic 的集中起来调整关键酶基因的相对表示层次在 artemisinin 包含了生合成。 | Liangyun Zhou Guang Yang Haifeng Sun Jinfu Tang Jian Yang Yizhan Wang Thomas Avery Garran Lanping Guo | 2017 | Frontiers of Medicine2017，11，1： | 0 |
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