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| 1 | The photoluminescence mechanism in carbon dots (graphene quantum dots, carbon nanodots, and polymer dots): Current state and future perspective显示文摘目前,光致发光(PL ) 的实际机制荧光灯碳点(CD ) 仍然是在研究人员之中的开的争论。因为 CD 的变化,为这些种碳材料总结 PL 机制是高度重要的;那么做能指导有效合成线路和新奇应用程序的开发。这评论将集中于 CD 的 PL 机制。三种类型荧光灯 CD 被包含:graphene 量点(GQD ) ,碳 nanodots (CND ) ,和聚合物点(PD ) 。四合理 PL 机制被证实了:被碳核心决定的量监禁效果或结合的 -domains, ;表面状态,它由碳脊梁和连接的化学的组的杂交坚定;分子状态,它完全坚定由荧光灯分子在 CD 的表面或内部上连接了;并且提高交叉连接的排放(C ) 效果。为 CD 给一篇彻底的摘要,范畴和合成线路,以及化学 / 物理的性质,简短预先被介绍。 | Shoujun Zhu Yubin Song Xiaohuan Zhao Jieren Shao Junhu Zhang Bai Yang | 2015 | Nano Research2015,8,2: | 120 |
| 2 | Modelling operation parameters of UAV on spray effects at different growth stages of corns显示文摘Currently,unmanned aerial vehicles(UAVs)were widely applied to spray for pest and disease control.However,spray effect can be further improved by setting operation parameters more reasonably and scientifically.Therefore,this study attempts to derive the relationship between operation parameters and spray effect.Different growth stages were distinguished by various corn heights.A six-rotor UAV was operated at different heights and velocities to test pesticides spray effects for corns at different growth stages.Different plant canopy coverage rate and penetrating coefficients were obtained,according to which,the effects on droplet deposition rate caused by different UAVs’operation parameters were analyzed.Droplet penetrating coefficients were applied as indexes to evaluate and select UAVs operation parameters for corns at different growth stages respectively.Mathematical models of droplet penetrating coefficients with UAVs operation parameters were established for corns at all growth stages.The determination coefficients(R2)of all models were greater than 0.90 and average relative errors were within 20%,which asserted high forecasting accuracy of droplet penetrating rate.With the help of the models,parameters like operating height away from the bottom of corns and UAVs velocities were further analyzed,which guided the optimization of parameter settings and selection of spray methods for corns at different growth stages. | Zheng Yongjun Yang Shenghui Zhao Chunjiang Chen Liping Yubin Lan Tan Yu | 2017 | International Journal of Agricultural and Biological Engineering2017,10,3: | 13 |
| 3 | GSA:Genome Sequence Archive显示文摘With the rapid development of sequencing technologies towards higher throughput and lower cost, sequence data are generated at an unprecedentedly explosive rate. To provide an efficient and easy-to-use platform for managing huge sequence data, here we present Genome Sequence Archive(GSA; http://bigd.big.ac.cn/gsa or http://gsa.big.ac.cn), a data repository for archiving raw sequence data. In compliance with data standards and structures of the International Nucleotide Sequence Database Collaboration(INSDC), GSA adopts four data objects(Bio Project, Bio Sample,Experiment, and Run) for data organization, accepts raw sequence reads produced by a variety of sequencing platforms, stores both sequence reads and metadata submitted from all over the world,and makes all these data publicly available to worldwide scientific communities. In the era of big data, GSA is not only an important complement to existing INSDC members by alleviating the increasing burdens of handling sequence data deluge, but also takes the significant responsibility for global big data archive and provides free unrestricted access to all publicly available data in support of research activities throughout the world. | Yanqing Wang Fuhai Song Junwei Zhu Sisi Zhang Yadong Yang Tingting Chen Bixia Tang Lili Dong Nan Ding Qian Zhang Zhouxian Bai Xunong Dong Huanxin Chen Mingyuan Sun Shuang Zhai Yubin Sun Lei Yu Li Lan Jingfa Xiao Xiangdong Fang Hongxing Lei Zhang Zhang Wenming Zhao | 2017 | Genomics, Proteomics & Bioinformatics2017,15,1: | 13 |
| 4 | NLRP3-dependent pyroptosis is required for HIV-1 gp120- induced neuropathology显示文摘The human immunodeficiency virus-1(HIV-1)envelope protein gp120 is the major contributor to the pathogenesis of HIVassociated neurocognitive disorder(HAND).Neuroinflammation plays a pivotal role in gp120-induced neuropathology,but how gp120 triggers neuroinflammatory processes and subsequent neuronal death remains unknown.Here,we provide evidence that NLRP3 is required for gp120-induced neuroinflammation and neuropathy.Our results showed that gp120-induced NLRP3-dependent pyroptosis and IL-1βproduction in microglia.Inhibition of microglial NLRP3 inflammasome activation alleviated gp120-mediated neuroinflammatory factor release and neuronal injury.Importantly,we showed that chronic administration of MCC950,a novel selective NLRP3 inhibitor,to gp120 transgenic mice not only attenuated neuroinflammation and neuronal death but also promoted neuronal regeneration and restored the impaired neurocognitive function.In conclusion,our data revealed that the NLRP3 inflammasome is important for gp120-induced neuroinflammation and neuropathology and suggest that NLRP3 is a potential novel target for the treatment of HAND. | Xiaolong He Weijun Yang Zhijie Zeng Yi Wei Jie Gao Bao Zhang Li Li Liqun Liu Yu Wan Qing Zeng Zelong Gong Liting Liu Hanyun Zhang Yubin Li Shaojie Yang Tongtong Hu Lixian Wu Eliezer Masliah Shenghe Huang Hong Cao | 2020 | Cellular & Molecular Immunology2020,17,3: | 11 |
| 5 | Yolk-shell structured Co-C/Void/Co9S8 composites with a tunable cavity for ultrabroadband and efficient low- frequency microwave absorption显示文摘 | Xiaofang Liu Chengcheng Hao Lihua He Cheng Yang Yubin Chen Chengbao Jiang Ronghai Yu | 2018 | Nano Research2018,11,8: | 10 |
| 6 | Design and test of operation parameters for rice air broadcasting by unmanned aerial vehicle显示文摘Considering the difficulty of broadcasting in the small plots and complex terrain in South China,this research aimed to explore a new efficient broadcasting way and figure out advisable operation parameters by using a hollow 12-axis,rotor-wing Unmanned Aerial Vehicle(UAV)which is typically made up of four groups of solid support structure,with each consisting of three axes and two rotor wings.A 3.7 L reverse pyramid-shape seed hopper with a 60 mm×13 mm rectangular outlet at the bottom was designed to realize self-gravity seeding.Rice seed firstly directly falls on the rotating disc driven by direct-current dynamo before being sown.The disc was located 120 mm above the ground,with a diameter of 350 mm.Under constant flight conditions,parameters of the on-board broadcasting devices(dropping speed referring to speed for the outlet and the broadcasting speed for the disc’s rotation speed)determine the uniformity of air broadcasting.The FUTABA T8FG transmitter and receiver system were employed as the remote control device.When the UAV flies at 3 m/s and 2 m above the ground with an expected seeding of 180 grain/m^(2),the RD(Right Down)knob marked 29 and LD(Left Down)knob marked-24 with a disc rotation speed of 900 r/min,the broadcasting lasts for 15 seconds with a 25%opening(1.95 cm^(2))of rectangular outlet.In order to verify the feasibility of air broadcasting parameters,the project team carried out a field broadcasting test by using a hollow multi-rotor UAV at Zhongluotan Test Base in Guangzhou in July,2014.In the square field plots of 0.09 hm^(2),flying path of air broadcasting operation was designed.The collected sampling data of broadcasting quantity per unit area after the test showed that there were,on average,187.4 grains/m^(2)of the five sampling points with a standard deviation of 22.77,and a coefficient of variation of 12.15%which was far smaller than that of artificial broadcasting.The average yield of field broadcasted by UAV is 7705.5 kg/hm^(2)in 2014,implying that rice air broadcasting by UAV is feasible. | Li Jiyu Lan Yubin Zhou Zhiyan Zeng Shan Huang Cong Yao Weixiang Zhang Yang Zhu Qiuyang | 2016 | International Journal of Agricultural and Biological Engineering2016,9,5: | 10 |
| 7 | Deformation and stress distribution of the human foot after plantar ligaments release:A cadaveric study and finite element analysis显示文摘The majority of foot deformities are related to arch collapse or instability,especially the longitudinal arch.Although the relationship between the plantar fascia and arch height has been previously investigated,the stress distribution remains unclear.The aim of this study was to explore the role of the plantar ligaments in foot arch biomechanics.We constructed a geometrical detailed three-dimensional (3-D) finite element (FE) model of the human foot and ankle from computer tomography images.The model comprised the majority of joints in the foot as well as bone segments,major ligaments,and plantar soft tissue.Release of the plantar fascia and other ligaments was simulated to evaluate the corresponding biomechanical effects on load distribution of the bony and ligamentous structures.These intrinsic ligaments of the foot arch were sectioned to simulate different pathologic situations of injury to the plantar ligaments,and to explore bone segment displacement and stress distribution.The validity of the 3-D FE model was verified by comparing results with experimentally measured data via the displacement and von Mise stress of each bone segment.Plantar fascia release decreased arch height,but did not cause total collapse of the foot arch.The longitudinal foot arch was lost when all the four major plantar ligaments were sectioned simultaneously.Plantar fascia release was compromised by increased strain applied to the plantar ligaments and intensified stress in the midfoot and metatarsal bones.Load redistribution among the centralized metatarsal bones and focal stress relief at the calcaneal insertion were predicted.The 3-D FE model indicated that plantar fascia release may provide relief of focal stress and associated heel pain.However,these operative procedures may pose a risk to arch stability and clinically may produce dorsolateral midfoot pain.The initial strategy for treating plantar fasciitis should be non-operative. | LIANG Jun YANG YunFeng YU GuangRong NIU WenXin WANG YuBin | 2011 | Science China(Life Sciences)2011,54,3: | 8 |
| 8 | Effects of modified Lingguizhugan decoction combined with weekend fasting on metabolic syndrome显示文摘OBJECTIVE:To assess the therapeutic effect of weekend fasting and administration of a modified Lingguizhugan decoction on metabolic syndrome(MetS).METHODS:Twenty-one patients with MetS were recruited from the First Affiliated Hospital of Sun Yat-Sen University.Fasting plasma glucose(FPG),30-min and 2-h post-prandial blood glucose(PG),fasting serum insulin(FINS),blood pressure(BP),body mass index(BMI),waist circumference(WC),homeostasis model assessment for insulin resistance index(HOMA-IR),and levels of triglyceride(TG),total cholesterol(TC),low-density lipoprotein-cholesterol(LDL-C),and high-density lipoprotein cholesterol(HDL-C)were tested.Patients were allowed to drink only water and a Chinese herbal decoction during weekends.All samples were tested again after 12 weeks of treatment.RESULTS:FPG,30-min PG,2-h PG,FINS,LDL-C,systolic BP,diastolic BP,BMI,WC,and HOMA-IR de-creased significantly(P<0.05)compared with before treatment.Levels of TG,TC,and HDL-C did not change significantly.CONCLUSION:Weekend fasting improved glucose metabolism,lowered BP,reduced LDL-C levels,BMI,and WC.These data suggest that weekend fasting may be an effective therapy for MetS by protection against coronary atherosclerosis. | Yubin Yang Qiong Li Shuqing Chen Bin Ke Yinjuan Huang Jian Qin | 2014 | Journal of Traditional Chinese Medicine2014,34,1: | 8 |
| 9 | Overburden failure and the prevention of water and sand inrush during coal mining under thin bedrock显示文摘Coal mining under thin bedrock or thick unconsolidated soil layers brings mining problems related to these special geological conditions. The meaning of the term ''thin bedrock'' is defined through the thick- ness statistics of the coal seam and the bedrock layer. The coal-bearing strata having thick, unconsoli- dated aquifers and thin bedrock located at the Taiping Coal Mine in Shandong province were taken as a geological prototype for subsequent study. The geological, hydro-geological and engineering character- istics of the thin bedrock were analyzed. An engineering geological model was than established. Overbur- den failure and the development of ''Three Zones'' were studied by physical model tests. The rupture pattern and rock failure were analyzed for mining conditions under thin bedrock. The height of the caving zone and the freely flowing water fractured zone of different mining thicknesses were separately calcu- lated. The results show that a mining thickness greater than 3.5 m causes the height of the freely flowing water fractured zone to be sufficient to touch the weathered zone and the bottom of the Quaternary sys- tem aquifer, to various degrees. This, then, would lead to water and sand inrush into the working face. Measures to prevent water and sand flow inrush disasters by eliminating the power source are put fore- word. A field dewatering scheme was designed and observational data were obtained. The dewatering project had an obvious effect and the water level at working face number 8309 dropped to a safe level. The average draw down of the groundwater was observed to be 7.86 m. This showed that the dewatering project played a role in decreasing the hydraulic pressure and ensuring safety mining. | Yang Weifeng Xia Xiaohong Zhao Guorong Ji Yubin Shen Dingyi | 2011 | Mining Science and Technology2011,21,5: | 6 |
| 10 | Effect of Linguizhugan decoction on hyperlipidemia rats with intermittent fasting显示文摘OBJECTIVE:To explore the effect of Linguizhugan decoction on hyperlipidemia rats with caloric restriction.METHODS:The hyperlipidemia model of rat was induced by high fat diet for 8 weeks.After the model was established,26 rats were randomly divided into 4 groups:the control group(n=6),the model group(n=6),the intermittent fasting(IF) group(n= 8),and the IF and herbal medicine(IFH) group(n= 6).IF group was applied intermittent fasting every other day.The IFH group was given Linguizhugan decoction every day and intermittent fasting every other day.Blood samples were taken at the end of 16 weeks,and serum ghrelin and lipid was tested.RESULTS:Serum ghrelin in the IF group significantly increased(P<0.01).Serum ghrelin in IFH group was lower than the IF group(P<0.05),but higher than the model group(P<0.01).CONCLUSION:Linguizhugan decoction may play a part in regulation of energy and appetite in hyperlipidemia rats with IF. | Yubin Yang Jian Qin Bin Ke Junjie Zhang Lanying Shi Qiong Li | 2013 | Journal of Traditional Chinese Medicine2013,33,2: | 6 |
| 11 | Design and test of fault monitoring system for corn precision planter显示文摘With the growing demand and working complexity of corn precision planter,it becomes more important to monitor the working performance through intelligent systems.A new fault monitoring system for corn precision planters was designed and tested.This system consisted of the information acquisition module,controller module,alarm module,input module and display module.A capacitive sensor was utilized to monitor the seed flow without changing the track of a precision planter.This system can monitor the whole sowing process of a seed-metering device in real-time.The sowing status,fault type and fault location can be displayed on liquid crystal display(LCD).Warning light on the LCD reminds the operator of abnormal conditions.Bench tests and field tests showed that the minimum monitoring accuracies of missing sowing and total sowing number were 92.11%and 94.28%,respectively,and the seed level sensor and the opener sensor worked well.This system can accurately prompt the seed-metering mechanism in real-time. | Qi Jiangtao Jia Honglei Li Yang Yu Haibo Liu Xinhui Lan Yubin Feng Xianzhen Yang Yongxi | 2015 | International Journal of Agricultural and Biological Engineering2015,8,6: | 6 |
| 12 | 3D building modeling,organization and application in digital city system显示文摘The real world is a three-dimensional(3D)space requiring that 3D geospatial information applications be developed in alignment with the observer’s visual and perceptive habits.Particularly,3D building model data are required in a wide range of areas such as urban planning,environmental protection,real estate management and emergency response.At the same time,the development of Web service[LU1]technologies allows the possibility of the widely distributed 3D geospatial data on the web.3D city building model with its related information is an important part in the construction of a digital city system,and has become a staple resource on the web nowadays.In view of the hierarchical representation of a 3D building model,an abstract of a 3D building model based on structure details is studied,and a novel representation approach named 3D transparent building hierarchical model is presented in this paper.This approach fully uses both the existing 3D modeling technologies and CAD constructing mapping data.By the spatial relationship description,structural components inside a building can be represented and integrated as hierarchical models in a unified 3D space.In addition,based on the characteristics of the 3D building model data,a service-oriented architecture and Web service technologies for 3D city building models are discussed.The aim of the approach is that 3D city building models can be used as a kind of data resource service on the web,and can also exist independently in various different web applications. | YANG Xue 1,WENG JingNong 1,2,XIA YuBin 2,WU Lun 3 & SUI ZhengWei 3 1 College of Software,Beihang University,Beijing 100191,China 2 College of Computer,Beihang University,Beijing 100191,China 3 Institute of Remote Sensing and GIS,Peking University,Beijing 100871,China | 2010 | Science China(Technological Sciences)2010,53,S1: | 4 |
| 13 | Impacts of different methylprednisolone administration routes in patients with sudden hearing loss or Meniere’s disease显示文摘Background:Evidence suggests that glucocorticoids are important in the treatment of sudden hearing loss(SHL)and Meniere’s disease(MD).However,different glucocorticoid administration methods may have a significant impact on treatment outcomes.Objective:This study aimed to investigate effects of different glucocorticoid administration methods on sudden hearing loss and Meniere’s disease.Methods:In this study,glucocorticoids were administered orally in 18 patients,by retroauricular injection in 15 patients and by intratympanic injection in 15 patients.White blood cell(WBC)count,serum Kt,fasting plasma glucose(FPG),body temperature,heart rate and blood pressure were used to evaluate effects of glucocorticoids on patients with hearing loss.Visual analog scale(VAS)of pain and sleep disorders were also surveyed,and pure tone audiometry(PTA)results were compared among groups to evaluate efficacy of different glucocorticoids administration methods.Result:WBC count,heart rate and blood pressure were higher in patients taking oral glucocorticoids,while body temperature,serum Kt and FPG levels did not change in all three groups.However,patients who received intratympanic injection of glucocorticoids experienced more pain,while those taking oral glucocorticoids reported more sleep impairment.Treatment efficacy on hearing loss was not significantly different among the three groups.Conclusion:These findings suggest that systemic glucocorticoid administration can result in greater whole body responses than local administration,but with similar hearing treatment efficacy. | Dan Chen Zhipeng Li Qilin Zhou Yubin Chen Luoying Yang Jingqian Tan Xiangli Zeng Peng Li | 2020 | Journal of Otology2020,15,4: | 4 |
| 14 | Performance Analysis Applications in Virtual of Interactive Desktop Machine Environment显示文摘 | YANG Chun NIU Yan XIA Yubin CHENG Xu | 2008 | Chinese Journal of Electronics2008,17,2: | 4 |
| 15 | Optoelectronic convolutional neural networks based on time-stretch method显示文摘In this paper, a new architecture of optoelectronic convolutional neural networks(CNNs) based on time-stretch method is proposed. In this loop-shaped structure mainly composed of fiber optical and electronic devices, computations of data from each layer of CNN which are carried by light pulses with high repetition rate can be accomplished in a serial way. Therefore, a 5-layer CNN with two convolution layers,two mean pooling layers and one fully-connected layer are implemented. Under the test of handwriting digit recognition, its accuracy can reach up to 95% under ideal circumstances. Tests under different relative noise levels have been conducted and analyzed as well. | Yubin ZANG Minghua CHEN Sigang YANG Hongwei CHEN | 2021 | Science China(Information Sciences)2021,64,2: | 3 |
| 16 | Electrochemical Properties of Electrodes with Different Shapes and Diffusion Kinetic Analysis of Microbial Fuel Cells on Ocean Floor显示文摘Microbial fuel cell(MFC) on the ocean floor is a kind of novel energy-harvesting device that can be developed to drive small instruments to work continuously.The shape of electrode has a great effect on the performance of the MFC.In this paper,several shapes of electrode and cell structure were designed,and their performance in MFC were compared in pairs:Mesh(cell-1) vs.flat plate(cell-2),branch(cell-3) vs.cylinder(cell-4),and forest(cell-5) vs.disk(cell-6) FC.Our results showed that the maximum power densities were 16.50,14.20,19.30,15.00,14.64,and 9.95 mWm-2 for cell-1,2,3,4,5 and 6 respectively.And the corre-sponding diffusion-limited currents were 7.16,2.80,18.86,10.50,18.00,and 6.900 mA.The mesh and branch anodes showed higher power densities and much higher diffusion-limited currents than the flat plate and the cylinder anodes respectively due to the low diffusion hindrance with the former anodes.The forest cathode improved by 47% of the power density and by 161% of diffusion-limited current than the disk cathode due to the former's extended solid/liquid/gas three-phase boundary.These results indicated that the shape of electrode is a major parameter that determining the diffusion-limited current of an MFC,and the differences in the elec-trode shape lead to the differences in cell performance.These results would be useful for MFC structure design in practical applica-tions. | FU Yubin LIU Jia SU Jia ZHAO Zhongkai LIU Yang XU Qian | 2012 | Journal of Ocean University of China2012,11,1: | 3 |
| 17 | Ecological niches and blood sources of sand fly in an endemic focus of visceral leishmaniasis in Jiuzhaigou,Sichuan,China显示文摘Background:Sand fly Phlebotomus chinensis is a principle vector for the visceral leishmaniasis(VL)in China with a wide geographic distribution.Jiuzhaigou,Sichuan is a mountain type endemic area of VL in China.Long term effective control efforts in the region have successfully reduced VL transmission.To assess the current status of the sand flies and their ecological aspects in the region,a survey was conducted in the summer of 2014 and 2015.Methods:Sand fly specimens were collected by light traps in a village and blood sources were identified by PCR and sequencing of the mitochondrial cytochrome b gene.Results:In a rock cave,65.2%–79.8%of collected sand flies were male.On a rabbit farm,92.9%–98.8%of specimens were female.In pig pens,61.1%of specimens were female.Some females had visible blood residues.The feeding rate was 49.4%from the pig pens,12.3%from the cave,and only 1.7%from the rabbit farm.Pig,rabbit,chicken,dog,and human blood were detected in the fed specimens.Swine blood,present in all tested samples,was a preferred blood source,while chicken and dog blood were present in a third of the samples.Conclusions:In Jiuzhaigou County,Sichuan Province of China,the considerable sandfly density and the peridomestic feeding behavior all increases the risk of VL transmission,and insecticide spraying in animal sheds could be exploited to reduce sand fly populations in human surroundings. | Huiying Chen Kaili Li Hua Shi Yong Zhang Yu Ha Yan Wang Jinjin Jiang Yubin Wang Zhenzhou Yang Jiannong Xu Yajun Ma | 2016 | Infectious Diseases of Poverty2016,5,1: | 3 |
| 18 | Room-Temperature Solution-Processed PbS Quantum Dot Solar Cells显示文摘Summary of main observation and conclusion Colloidal quantum dots(CQDs)are attractive absorber materials for highefficiency photovoltalcs be-cause of their facile solution processing,bandgap tunability due to quant um confinement effect,and multi-exciton generation.To date,all published performance records for PbS CQDs solar cells have been based on the conventional hot-injection synthesis method.This method usually requires rela-tively strict conditions such as high temperature and the utilty of expensive source material pyrophoric bis(trimethylsilyl)sulfide(TM5-S),limiting the potential for large-scale and low-cost synthesis of Pbs CQDs.Here we report a facile room-temperature synthetic method to produce high-quality Pbs CQDs through inexpensive ionic source materials including Pb NOl2 and Na:5 in the presence of triethanolamine(TEA)as the stabilizing ligand.The PbS CQDs were successfully prepared with an average particle size of about 5 nm.Solar cells based on the as-synthesized PbS CQDs show a preliminary power conversion fficiency of 1.82%.This room-temperature and low-cost synth esis of PbS CQDs will further benefit the development of solution-processed CQD solar cells. | Yubin Xue Shun-Chang Liu Xinsheng Liu Yusi Yang Yimin Zhang Ding-Jiang Xue Jin-Song Hu | 2020 | Chinese Journal of Chemistry2020,38,4: | 3 |
| 19 | The associated killing of hepatoma cells using multilayer drug-loaded mats combined with fast neutron therapy显示文摘Chemotherapeutic and radiation therapy have emerged as two most important treatment strategies to treat cancer in clinical practice;however,to improve anticancer efficacy,combination chemotherapy still remains challenge.Dichloroacetate(DCA)could produce significant cytotoxic effects in certain tumor cells through its distinct mechanism.Radiation therapy with fast neutrons(FNT)has high relative biolgical effectiveness compared to other radiotherapeutics.Herein,we reported the combination chemotherapy with FNT for effective tumor growth inhibition with the assistance of a multilayered nanofiber loading DCA and DCA derivatives.We first synthesized a biodegradable polylysine to condense DCA with negative charge,or to conjugate DCA by condensing synthesis,to obtain Ion-DCA and Co-DCA,respectively.DCA,Ion-DCA or Co-DCA was then loaded into fibers to form multilayer drug-loaded mats.Upon adhesion on the surface of subcutaneous and orthotopic liver tumors,the multilayer drug-loaded mats realized a controllable release of DCA,which reversed the Warburg effect and inhibited cancer cell proliferation.Meantime,irradiation of fast neutrons could seriously damage DNA structure.Combination of the controllable release of DCA and FNT resulted in synergistic cell apoptosis in vitro,and the tumor inhibition in vivo.This study thus provides a new approach to integrate chemotherapy and FNT with the assistance of biocompatible nanofiber for synergistic tumor therapy. | Yanxin Qi Shiwei Jing Shasha He Hejian Xiong Guohua Yang Yubin Huang Ningyi Jin | 2021 | Nano Research2021,14,3: | 2 |
| 20 | Air plasma-sprayed high-entropy (Y_(0.2)Yb_(0.2)Lu_(0.2)Eu_(0.2)Er_(0.2))_(3)Al_(5)O_(12) coating with high thermal protection performance显示文摘High-entropy rare-earth aluminate(Y_(0.2)Yb_(0.2)Lu_(0.2)Eu_(0.2)Er_(0.2))_(3)Al_(5)O_(12)(HE-RE_(3)Al_(5)O_(12))has been considered as a promising thermal protection coating(TPC)material based on its low thermal conductivity and close thermal expansion coefficient to that of Al2O3.However,such a coating has not been experimentally prepared,and its thermal protection performance has not been evaluated.To prove the feasibility of utilizing HE-RE_(3)Al_(5)O_(12) as a TPC,HE-RE_(3)Al_(5)O_(12) coating was deposited on a nickelbased superalloy for the first time using the atmospheric plasma spraying technique.The stability,surface,and cross-sectional morphologies,as well as the fracture surface of the HE-RE_(3)Al_(5)O_(12) coating were investigated,and the thermal shock resistance was evaluated using the oxyacetylene flame test.The results show that the HE-RE_(3)Al_(5)O_(12) coating can remain intact after 50 cycles at 1200℃ for 200 s,while the edge peeling phenomenon occurs after 10 cycles at 1400℃ for 200 s.This study clearly demonstrates that HE-RE_(3)Al_(5)O_(12) coating is effective for protecting the nickel-based superalloy,and the atmospheric plasma spraying is a suitable method for preparing this kind of coatings. | Kailun WANG Jinpeng ZHU Hailong WANG Kaijun YANG Yameng ZHU Yubin QING Zhuang MA Lihong GAO Yanbo LIU Sihao WEI Yongchun SHU Yanchun ZHOU Jilin HE | 2022 | Journal of Advanced Ceramics2022,11,10: | 2 |