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| 1 | Evidence chain-based causality identification in herb-induced liver injury: exemplification of a well-known liver-restorative herb Polygonum multiflorum显示文摘草药的药最近在美国作为导致药的肝损害(DILI ) 的第二个很普通的原因被认出了。然而,识别一些植物的 DILI 诱发性的可靠方法例如 Heshouwu (蓼 multiflorum 的弄干的根) ,留下缺乏。在这研究,有肝机能障碍和 Heshouwu DILI 的 147 个报导文学的案例的 12 307 个住院病人的一个总数被屏蔽。一个一般算法仅仅显示了那 22.5%(9/40 ) 并且(45/147 ) 分别地, 30.6% 所有住院和文学案例报告表明 Heshouwu 的 DILI 诱发性的高概率。由对比,(19/20 )95% 生药学,植物化学,和 metabolomic 有希望地调查的所有情况测试展出高度可能的诱发性,包括不正确地以前被归因的一个病人和从由 pharmacognostic 证据的 Heshouwu 诱发性被排除的一个案例。污染也是的毒素(重金属,杀虫剂,和 mycotoxins ) 从 Heshouwu DILI 诱发性排除了。为 Heshouwu DILI 诊断地址安全的这些屏蔽方法的客观性担心考虑包含芪的草药的药和饮食的补充。 | Jiabo Wang Zhijie Ma Ming Niu Yun Zhu Qingsheng Liang Yanling Zhao Jingyuan Song Zhaofang Bai Yaming Zhang Ping Zhang Na Li Yakun Meng Qi Li Lushan Qin Guangju Teng Junling Cao Baosen Li Shilin Chen Yonggang Li Zhengsheng Zou Honghao Zhou Xiaohe Xiao | 2015 | Frontiers of Medicine2015，9，4： | 47 |
| 2 | Crustal velocity structure in the Emeishan large igneous province and evidence of the Permian mantle plume activity显示文摘The Emeishan large igneous province(ELIP) in SW China is interpreted to be associated with an ancient mantle plume. Most of the constraints on the role of mantle plume in the generation of the Emeishan flood basalts were provided by geological and geochemical methods, but the geophysical investigation is very limited. In order to better understand the deep structure and features of ELIP, we have studied the crustal velocity structure using the data acquired from the Lijiang-Panzhihua-Qingzhen wide-angle seismic profile. This profile crosses the three sub-zones of the ELIP(the inner, intermediate, and outer zones), divided based on the differential erosion and uplift of the Maokou limestone. The results provided by the active source seismic experiment demonstrate:(1) The average depth of the crystalline basement along the profile is about 2 km.(2) The middle crust in the Inner Zone is characterized by high-velocity anomalies, with the average velocity of 6.2-6.6 km/s, which is about 0.1– 0.2 km/s higher than the normal one. The velocity of the lower crust in the inner zone is 6.9-7.2 km/s, higher than those observed in the intermediate and outer zones(6.7-7.0 km/s). Relatively low velocity anomalies appear in the upper, middle and lower crusts near the junction of the inner zone and intermediate zone, probably due to the effect of the Xiaojiang fault(XJF).(3) The average velocity of the crust is comparatively low on both sides of XJF, especially on the east side, and the average velocity of the consolidated continental crust is also low there. This may suggest that the XJF extends at least down to 40 km deep, even beyond through the crust.(4) The depth to the Moho discontinuity decrease gradually from 47-53 km in the inner zone, via 42-50 km in the intermediate zone to 38-42 km in the outer zone. In the inner zone, the Moho uplifts locally and the(consolidated) crust is characterized by high-velocity anomalies, which are likely related to intensive magma intrusion and underplating associated with melting of plume head. Overall the crustal velocity structure in the study area recorded the imprint left by the Permian Emeishan mantle plume. | XU Tao ZHANG ZhongJie LIU BaoFeng CHEN Yun ZHANG MingHui TIAN XiaoBo XU YiGang TENG JiWen | 2015 | Science China Earth Sciences2015，58，7： | 36 |
| 3 | Multi-energy Storage System Model Based on Electricity Heat and Hydrogen Coordinated Optimization for Power Grid Flexibility显示文摘Based on decreasing the flexibility of the power grid through the integration of large-scale renewable energy,a multi-energy storage system architectural model and its coor-dination operational strategy with the same flexibility as in the pumped storage power station and battery energy storage system(BESS)are studied.According to the new energy fluctuation characteristics and the different peak valley parameters in the power grid,this paper proposes a electricity heat hydrogen multi-energy storage system(EHH-MESS)and its coordination and optimization operational model to reduce the curtailment of wind power and photovoltaic(PV)to the power grid and improve the flexibility of the power grid.Finally,this paper studied the simulation model of an energy storage optimization control strategy after the multi-energy storage system is connected to the distribution networks,and analyzed three operational modes of the multi-energy storage system.The simulation results show that the EHH-MESS proposed in this paper has a better power grid regulation flexibility and economy,and can be used to replace the battery energy storage system based on MATLAB. | Yun Teng Zedi Wang Yan Li Qian Ma Qian Hui Shubin Li | 2019 | CSEE Journal of Power and Energy Systems2019，5，2： | 38 |
| 4 | A Model of Electro-thermal Hybrid Energy Storage System for Autonomous Control Capability Enhancement of Multi-energy Microgrid显示文摘In view of the problem of low self-service capability of the microgrid due to the high operating cost and low capacity of the traditional battery energy storage system.In this paper,an electrothermal hybrid energy storage model based on electricity,hydrogen and thermal energy conversion and storage is introduced,and a microgrid autonomous operational strategy is proposed.First,the addition of the power to hydrogen transfer equipment in the traditional combined heat and power(TCHP)system without battery energy storage is studied,and a micro gas turbine,electric to hydrogen transfer equipment and electric boiler based electrothermal energy storage system(ETSS)model is established.Aiming at the lowest comprehen-sive operating cost of multiple energy sources in a microgrid and maximizing the consumption of curtailed wind,the multi-objective scheduling model of an electrothermal hybrid energy storage system is established,then the multi-energy autonomous operational strategy of a microgrid is proposed.Lastly,the simulation of a multi-energy microgrid in Northeast China is taken as an example.The results of the simulation showed that compared with a combined heat and power microgrid system considering conventiona battery energy storage,a multi-energy microgrid system using electrothermal hybrid energy storage has better flexibility and economy,and can improve wind power accommodation. | Yun Teng Peng Sun Qian Hui Yan Li Zhe Chen | 2019 | CSEE Journal of Power and Energy Systems2019，5，4： | 20 |
| 5 | Transmission of climate change impacts from temperature change to grain harvests, famines and peasant uprisings in the historical China显示文摘Because of the complexity of social responses to climate change,as well as limitations of proxy data concerning interactions between climate change and human responses,the social impacts of past climate change and associated response mechanisms,thus,require further investigation.To shed light on the transmission of climate change impacts within historical Chinese society,we selected 30-year resolution sequences of temperature anomalies in eastern China and 10-year resolution sequences of grain harvest grades,famine indices,and frequencies of peasant uprisings in China over the past 2000 years.Using a food security perspective,we analyzed the impacts of temperature changes historically transmitted through Chinese production,population,and social subsystems,and differences in transmission characteristics between cold and warm units.Our results were as follows.(1)From 210 BC to 1910 AD,temperature changes in China were significantly positively correlated with grain harvest grades(correlation coefficient,0.338),and significantly negatively correlated with famine indices,and frequencies of peasant uprisings(correlation coefficients,-0.301 and-0.277,respectively).The correlation coefficients between famine indices and grain harvest grades or frequencies of peasant uprisings were very low.(2)There was a higher proportion of bumper or normal harvests(86.5%of the total decades),more moderate and mild famines(76%),and a lower proportion of peasant uprisings(33.3%)in the 30-year warm units.Conversely,there was a higher proportion of poor or normal harvests(70.7%),a greater proportion of moderate and severe famines(77.6%),and more peasant uprisings(51.7%)in the 30-year cold units.(3)Of the 23 main transmission pathways extending from temperature change to the social subsystem,13 occurred in cold units,of which 7 had an endpoint of peasant uprisings,and 10 occurred in warm units of which 3 had an endpoint of peasant uprisings.The main transmission pathways that were more likely to be associated with the impacts of temperature change were:Cold→poor harvests→severe famines→more uprisings;cold→poor harvests→moderate famines→more uprisings;warm→bumper harvests→mild famines→no uprisings;warm→bumper harvests→moderate harvests→no uprisings;warm→normal harvests→mild famines→no uprisings;and warm→normal harvests→moderate famines→no uprisings.(4)The transmission of the impacts of temperature change was a complex process.Within this process,famine was most prone to being modulated by human society.In the transmission pathways from the production to the social subsystem,there was a stepwise decrease in the occurrence rate of decades that were probably affected by climate change.In all cold units,10.4%of decades ending in more uprisings were most likely to be associated with the impacts of temperature change.In all warm units,47.9%of decades ending in no uprisings were most likely to be associated with the impacts of temperature change.This research can contribute a better understanding on the past interaction mechanisms and processes within the human-climate-ecosystem complex,as well as a better response to the impacts of the ongoing climate change. | FANG XiuQi SU Yun YIN Jun TENG JingChao | 2015 | Science China Earth Sciences2015，58，8： | 15 |
| 6 | Esophageal Helicobacter pylori colonization aggravates esophageal injury caused by reflux显示文摘AIM: To investigate esophageal Helicobacter pylori(H. pylori) colonization on esophageal injury caused by reflux and the related mechanisms. METHODS: An esophagitis model, with acid and bile reflux, was surgically produced in male rats. The rats were randomly divided into either:(1) an esophagogastroduodenal anastomosis(EGDA) group;(2) an EGDA with H. pylori infection group;(3) a pseudo-operation with H. pylori infection group; or(4) a pseudooperation group. All rats were kept for 36 wk. Based on the location of H. pylori colonization, the EGDA rats with H. pylori infection were subdivided into those with concomitant esophageal H. pylori colonization or those with only gastric H. pylori colonization. The esophageal injuries were evaluated grossly and microscopically. The expressions of CDX2 and MUC2 were determined by real-time polymerase chain reaction(RT-PCR) and immunohistochemistry. Ki-67 antigen expression was determined by immunohistochemistry. The m RNA levels of cyclin D1, c-Myc, Bax and Bcl-2 were determined by RT-PCR. Cell apoptosis was evaluated using the Td Tmediated d UTP nick-end labeling method.RESULTS: Esophagitis, Barrett's esophagus(BE), and esophageal adenocarcinoma(EAC) developed in rats that underwent EGDA. When comparing rats with EGDA and concomitant esophageal H. pylori colonization to EGDA-only rats, the severity of injury(87.9 ± 5.2 vs 77.2 ± 8.6, macroscopically, 92.5 ± 8.0 vs 83.8 ± 5.5, microscopically, both P < 0.05) and the incidences of BE(80.0% vs 33.3%, P = 0.055) and EAC(60.0% vs 11.1%, P < 0.05) were increased. These increases were associated with upregulation of CDX2 and MUC2 m RNA(10.1 ± 5.4 vs 3.0 ± 2.9, 8.4 ± 4.6 vs 2.0 ± 3.2, respectively, P s < 0.01) and protein(8.1 ± 2.3 vs 3.3 ± 3.1, 7.3 ± 4.0 vs 1.8 ± 2.7, respectively, all P < 0.05). The expression of Ki-67(8.9 ± 0.7 vs 6.0 ± 1.7, P < 0.01) and the presence of apoptotic cells(8.3 ± 1.1 vs 5.3 ± 1.7, P < 0.01) were also increased significantly in rats with EGDA and concomitant esophageal H. pylori colonization compared with rats with EGDA only. The m RNA levels of cyclin D1(5.8 ± 1.9 vs 3.4 ± 1.3, P < 0.01), c-Myc(6.4 ± 1.7 vs 3.7 ± 1.2, P < 0.01), and Bax(8.6 ± 1.6 vs 5.1 ± 1.3, P < 0.01) were significantly increased, whereas the m RNA level of Bcl-2(0.6 ± 0.3 vs 0.8 ± 0.3, P < 0.01) was significantly reduced in rats with EGDA and concomitant esophageal H. pylori colonization compared with rats with EGDA only.CONCLUSION: Esophageal H. pylori colonization increases esophagitis severity, and facilitates the development of BE and EAC with the augmentation of cell proliferation and apoptosis in esophageal mucosa. | Yun-Xiang Chu Wei-Hong Wang Yun Dai Gui-Gen Teng Shu-Jun Wang | 2014 | World Journal of Gastroenterology2014，20，42： | 12 |
| 7 | Three-dimensional-printed individualized porous implants:A new“implant-bone”interface fusion concept for large bone defect treatment显示文摘Bone defect repairs are based on bone graft fusion or replacement.Current large bone defect treatments are inadequate and lack of reliable technology.Therefore,we aimed to investigate a simple technique using three-dimensional(3D)-printed individualized porous implants without any bone grafts,osteoinductive agents,or surface biofunctionalization to treat large bone defects,and systematically study its long-term therapeutic effects and osseointegration characteristics.Twenty-six patients with large bone defects caused by tumor,infection,or trauma received treatment with individualized porous implants;among them,three typical cases underwent a detailed study.Additionally,a large segmental femur defect sheep model was used to study the osseointegration characteristics.Immediate and long-term biomechanical stability was achieved,and the animal study revealed that the bone grew into the pores with gradual remodeling,resulting in a long-term mechanically stable implant-bone complex.Advantages of 3D-printed microporous implants for the repair of bone defects included 1)that the stabilization devices were immediately designed and constructed to achieve early postoperative mobility,and 2)that osseointegration between the host bone and implants was achieved without bone grafting.Our osseointegration method,in which the“implant-bone”interface fusion concept was used instead of“bone-bone”fusion,subverts the traditional idea of osseointegration. | Teng Zhang Qingguang Wei Hua Zhou Zehao Jing Xiaoguang Liu Yufeng Zheng Hong Cai Feng Wei Liang Jiang Miao Yu Yan Cheng Daoyang Fan Wenhao Zhou Xinhong Lin Huijie Leng Jian Li Xinyu Li Caimei Wang Yun Tian Zhongjun Liu | 2021 | Bioactive Materials2021，6，11： | 9 |
| 8 | 基于体波有限频层析成像的青藏高原南部和中部下方印度大陆岩石层俯冲和撕裂的三维图像显示文摘使用TIBET-31N无源地震台阵以及以前临时地震台阵记录到的远震体波数据进行了有限频层析成像反演,对青藏高原南部及中部的三维速度结构成像。在喜马拉雅和拉萨地块下方存在向北倾角40°的高速体。我们把这些高速异常区域解释为俯冲的印度大陆岩石层(ICL)。印度大陆岩石层似乎在青藏高原中部比东部向北延伸更多——沿85°E在31°N到达350km深处,而沿91°E则是在30°N到达350km深度。P波和S波低速异常区在当惹雍错裂谷、亚东—谷露裂谷和错那裂谷下方从下地壳延伸至≥180km深度,这表明青藏高原南部的裂谷可能包含了整个岩石层的变形。当惹雍错裂谷下方的异常区向下延伸到约180km,而亚东—谷露裂谷西部和错那裂谷东部的异常延伸到了超过300km的深度。亚东—谷露裂谷西部的低速区上地幔延伸至最北,并且似乎与青藏高原中部下方广阔的上地幔低速区相连。于是,北向俯冲的印度板块沿着南北走向的裂缝撕裂。这些裂缝允许或者导致的软流层上涌同青藏高原北部上地幔相类似。 | Xiaofeng Liang Yun Chen Xiaobo Tian Yongshun John Chen James Ni Andrea Gallegos Simon L.Klemperer Minling Wang Tao Xu Changqing Sun Shaokun Si Haiqiang Lan Jiwen Teng 左思成 | 2016 | 世界地震译丛2016，47，6： | 8 |
| 9 | Association of Overlapped and Un-overlapped Comorbidities with COVID-19 Severity and Treatment Outcomes: A Retrospective Cohort Study from Nine Provinces in China显示文摘Objective Several COVID-19 patients have overlapping comorbidities. The independent role of each component contributing to the risk of COVID-19 is unknown, and how some non-cardiometabolic comorbidities affect the risk of COVID-19 remains unclear.Methods A retrospective follow-up design was adopted. A total of 1,160 laboratory-confirmed patients were enrolled from nine provinces in China. Data on comorbidities were obtained from the patients’ medical records. Multivariable logistic regression models were used to estimate the odds ratio(OR) and 95% confidence interval(95% CI) of the associations between comorbidities(cardiometabolic or non-cardiometabolic diseases), clinical severity, and treatment outcomes of COVID-19.Results Overall, 158(13.6%) patients were diagnosed with severe illness and 32(2.7%) had unfavorable outcomes. Hypertension(2.87, 1.30–6.32), type 2 diabetes(T2 DM)(3.57, 2.32–5.49),cardiovascular disease(CVD)(3.78, 1.81–7.89), fatty liver disease(7.53, 1.96–28.96), hyperlipidemia(2.15, 1.26–3.67), other lung diseases(6.00, 3.01–11.96), and electrolyte imbalance(10.40, 3.00–26.10)were independently linked to increased odds of being severely ill. T2 DM(6.07, 2.89–12.75), CVD(8.47,6.03–11.89), and electrolyte imbalance(19.44, 11.47–32.96) were also strong predictors of unfavorable outcomes. Women with comorbidities were more likely to have severe disease on admission(5.46,3.25–9.19), while men with comorbidities were more likely to have unfavorable treatment outcomes(6.58, 1.46–29.64) within two weeks.Conclusion Besides hypertension, diabetes, and CVD, fatty liver disease, hyperlipidemia, other lung diseases, and electrolyte imbalance were independent risk factors for COVID-19 severity and poor treatment outcome. Women with comorbidities were more likely to have severe disease, while men with comorbidities were more likely to have unfavorable treatment outcomes. | MA Yan ZHU Dong Shan CHEN Ren Bo SHI Nan Nan LIU Si Hong FAN Yi Pin WU Gui Hui YANG Pu Ye BAI Jiang Feng CHEN Hong CHEN Li Ying FENG Qiao GUO Tuan Mao HOU Yong HU Gui Fen HU Xiao Mei HU Yun Hong HUANG Jin HUANG Qiu Hua HUANG Shao Zhen JI Liang JIN Hai Hao LEI Xiao LI Chun Yan LI Min Qing LI Qun Tang LI Xian Yong LIU Hong De LIU Jin Ping LIU Zhang MA Yu Ting MAO Ya MO Liu Fen NA Hui WANG Jing Wei SONG Fang Li SUN Sheng WANG Dong Ting WANG Ming Xuan WANG Xiao Yan WANG Yin Zhen WANG Yu Dong WU Wei WU Lan Ping XIAO Yan Hua XIE Hai Jun XU Hong Ming XU Shou Fang XUE Rui Xia YANG Chun YANG Kai Jun YUAN Sheng Li ZHANG Gong Qi ZHANG Jin Bo ZHANG Lin Song ZHAO Shu Sen ZHAO Wan Ying ZHENG Kai ZHOU Ying Chun ZHU Jun Teng ZHU Tian Qing ZHANG Hua Min WANG Yan Ping WANG Yong Yan 无 | 2020 | Biomedical and Environmental Sciences2020，33，12： | 8 |
| 10 | Association study of the single nucleotide polymorphisms in adiponectin-associated genes with type 2 diabetes in Han Chinese显示文摘Single-nucleotide polymorphisms (SNPs) of ADIPOQ, ADIPOR1, and ADIPOR2 have been associated with type 2 diabetes mellitus (T2DM), but there are many conflicting results especially in Chinese populations. To investigate the contribution of the adiponectin genes and their receptors to T2DM, a case-control study was performed and 11 SNPs of ADIPOQ, ADIPOR1, and ADIPOR2 were genotyped in 985 T2DM and 1,050 control subjects. rs16861194 (-11426 A>G) in the putative promoter of ADIPOQ was associated with T2DM (P = 0.007; OR = 1.29, 95% CI 1.08-1.55). None of the other 10 SNPs were associated with T2DM in this study, although rs2241766 and rs1501299 were reported to be associated with T2DM in previous Chinese studies. There was also no significant difference found from the ADIPOQ haplotype analysis, which contains rs16861194. In addition, we also assessed potential gene-gene interactions in three genes and no interactions were found. In conclusion, our results supported the ADIPOQ gene as a possible risk factor for type 2 diabetes in Han Chinese population. | Yabing Wang Di Zhang Yun Liu Yifeng Yang Teng Zhao Jie Xu Sheng Li Zuofeng Zhang Guoyin Feng Lin He He Xu | 2009 | Journal of Genetics and Genomics2009，36，7： | 7 |
| 11 | Salvianolic acids improve liver lipid metabolism in ovariectomized rats via blocking STAT-3/SREBP1 signaling显示文摘Postmenopausal women, who have reduced circulating estrogen levels, are more prone to develop obesity and related metabolic diseases than premenopausal women. The absence of safe and effective treatments for postmenopausal obesity has changed the focus to natural products as alternative remedies. Total salvianolic acids(TSA) are the major water-soluble ingredients of Danshen. Salvianolic acid(SA) is the major constituent of the TSA. Salvianolic acids, including TSA and SA, are widely used in traditional Chinese medicine. In the present study, ovariectomized rats and LO2 cells were used to study the effects of salvianolic acids on body weight gain and hepatic steatosis. Salvianolic acids reduced ovariectomy(OVX)-induced body weight gain, attenuated the expressions of hepatic lipogenic genes, such as sterol regulatory element binding protein(SREBP)1, fatty acid synthase(FAS), and stearoyl-CoA desaturase(SCD)1, and decreased the liver triglyceride(TG) and total cholesterol(TC). For the molecular mechanisms, OVX and high glucose-induced phosphorylation of signal transducer and activator of transcription(STAT)-3 was inhibited by salvianolic acids treatment. In LO2 cells, inhibition of STAT-3 by siRNA attenuated the increased expression of SREBP1 and TG induced by high glucose. Salvianolic acids reduced the upregulation of SREBP1 and TG induced by high glucose in LO2 cells. In conclusion, these findings illustrated that salvianolic acids markedly alleviated the lipid metabolism disorders and protected against the postmenopausal obesity. The underlying mechanism was probably associated with the regulation of STAT-3 signaling. | CHEN Juan YUE Jia LIU Jiao LIU Yun JIAO Kai-Lin TENG Meng-Ying HU Chun-Yan ZHEN Jing WU Mao-Xuan ZHOU Ming LI Zhong LI Yuan | 2018 | Chinese Journal of Natural Medicines2018，16，11： | 6 |
| 12 | Effects of the Fhb1 gene on Fusarium head blight resistance and agronomic traits of winter wheat显示文摘The gene Fhb1 has been used in many countries to improve wheat Fusarium head blight(FHB) resistance. To make better use of this gene in the Yellow-Huai River Valleys Winter Wheat Zone(YHWZ), the most important wheat-producing region of China, it is desirable to elucidate its effects on FHB resistance and agronomic traits in different genetic backgrounds. Based on a diagnostic marker for Fhb1, six BC2 populations were developed by crossing dwarf-male-sterile(DMS)-Zhoumai 16 to three Fhb1 donors(Ningmai 9, Ningmai 13, and Jianyang 84) and backcrossing to Zhoumai 16 and Zhoumai16’s derivative cultivars(Lunxuan 136 and Lunxuan 13) using marker-assisted backcross breeding. The progenies were assessed for FHB resistance and major agronomic traits.The Fhb1 alleles were identified using the gene-specific molecular marker. The plants with the Fhb1-resistant genotype(Fhb1-R) in these populations showed significantly fewer infected spikelets than those with the Fhb1-susceptible genotype(Fhb1-S). When Lunxuan 136 was used as the recurrent parent, Fhb1-R plants showed significantly fewer infected spikelets per spike than Fhb1-R plants produced using Lunxuan 13 as the recurrent parent, indicating that the genetic backgrounds of Fhb1 influence the expression of FHB resistance. Fhb1-R plants from the DMS-Zhoumai 16/Ningmai 9//Zhoumai 16/3/Lunxuan 136 population showed the highest FHB resistance among the six populations and a significantly higher level of FHB resistance than the moderately susceptible control Huaimai 20. No significant phenotypic differences between Fhb1-R and Fhb1-S plants were observed for the eight agronomic traits investigated. These results suggest that it is feasible to improve FHB resistance of winter wheat withoutreducing yield potential by introgressing Fhb1 resistance allele into FHB-susceptible cultivars in the YHWZ. | Teng Li Hongjun Zhang Yiwen Huang Zhenqi Su Yun Deng Hongwei Liu Chunyan Mai Guangjun Yu Huili Li Liqiang Yu Tongquan Zhu Li Yang Hongjie Li Yang Zhou | 2019 | The Crop Journal2019，7，6： | 6 |
| 13 | A Robust Control Strategy to Improve Transient Stability for AC-DC Interconnected Power System with Wind Farms显示文摘In view of the variable parameters that affect the transient stability of electromagnetic torque and mechanical torque balance in AC-DC system,and the uncertainty of wind power in large-scale interconnection of wind farm.This paper proposes a linear parameter varying(LPV)robust feedback control method for transient stability of interconnected systems.The proposed LPV robust feedback control method uses the DC channel power control and the mechanical power in the interconnected system as the control target to improve the transient stability of the interconnected system with wind farm channel.Firstly,aiming at the strong nonlinear characteristics of the interconnected system,the power balance and the wind power output uncertainty in the transient process,the transient process is designed as a linear model of variable parameters.Then,the H∞robust output feedback controller is designed according to the LPV model.The transient stability control strategy topology and transfer function of the interconnected system are proposed.Finally,the proposed scheme is verified by an interconnected system formed by four equal-value grids through AC and DC lines in a digital simulation platform.The results show that the LPV robust feedback control model proposed in this paper has better response characteristics and transient stability control effects for interconnected systems with wind power weak sendingend system. | Qian Hui Jinlu Yang Xia Yang Zhe Chen Yan Li Yun Teng | 2019 | CSEE Journal of Power and Energy Systems2019，5，2： | 6 |
| 14 | Serum Gamma-glutamyl Transferase Levels Predict Functional Outcomes after Aneurysmal Subarachnoid Hemorrhage显示文摘Objective We aim to explore the potential association between serum gamma-glutamyl transferase levels and functional outcome after aneurysmal subarachnoid hemorrhage in a Chinese population. Methods A total of 386 aneurysmal subarachnoid hemorrhage patients were included in the study from September 2007 to February 2015. Baseline serum gamma-glutamyl transferase levels and 6-month follow-up functional outcomes were determined. A poor outcome was defined as a modified ranking scale score of ≥ 3. The multivariable logistic model was used to analyze the relationship between serum gamma-glutamyl transferase and clinical outcomes after aneurysmal subarachnoid hemorrhage. Results The adjusted poor outcome rates of patients with gamma-glutamyl transferase levels of < 30 U/L, 30-50 U/L and ≥ 50 U/L were 16.7%, 19.6%, and 34.4%, respectively(P < 0.01). The age-sex and multivariable adjusted odds ratios(95% confidence intervals) of poor prognosis comparing the top group(≥ 50 U/L) with the lowest group(< 30 U/L) were 5.76(2.74-12.13), 6.64(2.05-21.52), and 6.36(1.92-21.02). A significant linear trend existed between gamma-glutamyl transferase level and aneurysmal subarachnoid hemorrhage prognosis. This association was also observed among nondrinkers. Conclusion Patients with higher gamma-glutamyl transferase levels were more likely to have a poor prognosis. Serum gamma-glutamyl transferase can be considered to be an independent predictor of functional outcomes after aneurysmal subarachnoid hemorrhage. | XU Tian WANG Wei ZHAI Lin ZHANG Yun Feng ZHOU Hong Zhi WU Xin Min LI Ai Hong XIE Li Li NING Xiao Jin JI Yu Teng WANG Hong Mei KE Kai Fu | 2017 | Biomedical and Environmental Sciences2017，30，3： | 5 |
| 15 | A New Perylenequinone from Hypomyces sp.显示文摘A new perylenequinone, named hypomycin A, was isolated from the mycelia of Hypomyces sp.. Its structure was elucidated on the basis of spectroscopic methods. | Wei Zhong LIU1*, Yun Xiu SHEN1, Xiang Feng LIU1, Yuan Teng CHEN2, Jin Lun XIE2 1Chemistry Teaching and Research Department, Binzhou Medical College, Binzhou 256603 2Fermentation Engineering Key Laboratory, Yunnan University, Kunming 650091 | 2001 | Chinese Chemical Letters2001，12，5： | 5 |
| 16 | Isolation and Purification of Polysaccharides from Cordyceps minlitaris and Its Inhibition on the Proliferation of Rat Glomerular Mesangial Cells显示文摘The crude polysaccharide was obtained by means of the decolorization of porphyrized Cordyceps minlitaris stroma with organic solvent, extraction with hot water, precipitation in 80% ethanol, and protein removal with the Sevag method. After purification with Sephadex G-75, two of its components, CMP-1 and CMP-2, were obtained. Through the assay of gel chromatography and polarimetry, CMP-1 was identified as pure polysaccharide. The results demonstrated that CMP-1 had favorable oxidation resistance activity, which could scavenge not only oxygen-free radicals in the self-oxidation system of pyrogallic acid, but also the hydroxide-free radicals in the Fenton system. The study focused on the effects of low, medium, and high dosages of CMP-1 in rat blood serum on the proliferation of glomerular mesangial cells in vitro. Through MTT Colorimetric analysis, the activities were compared among the blank control group and the Niaoduqing positive control group CMP-1 and CMP-2. The results shows that CMP-1 was able to inhibit the proliferation of rat glomerular mesangial cells effectively. Therefore, CMP-1, one component of polysaccharides of Cordyceps minlitaris, was certainly a potential remedy for hyperplastic glomerular nephritis, whose antioxidant activity could slow down the process of chronic renal failure(CRF) to some extent. | HOU A-li MENG Qing-fan AN Jin-shuang ZHU Kai FENG Yun TENG Li-rong | 2008 | Chemical Research in Chinese Universities2008，24，5： | 4 |
| 17 | Granular porous calcium carbonate particles for scalable and high-performance solar-driven thermochemical heat storage显示文摘Calcium carbonate is promising thermochemical heat storage material for next-generation solar power systems due to its high energy storage density,low cost,and high operation temperature.Researchers have tried to improve energy storage performances of calcium carbonate recently,but most researches focus on powders,which are not suitable for scalable applications.Here,novel granular porous calcium carbonate particles with very high solar absorptance,energy storage density,abrasive resistances,and energy storage rate are proposed for direct solar thermochemical heat storage.The average solar absorptance is improved by 234%compared with ordinary particles.Both cycle stability and abrasive resistances are excellent with almost no decay of energy storage density over 25 cycles nor apparent particle weight loss over 24 h of continuous operation insides a planetary ball mill.In addition,the decomposition temperature is reduced by 2.8%–5.6%while the reaction rate of heat storage is enhanced by 80%–205%depending on the CO_(2) partial pressure.The decomposition process of doped granular porous CaCO_(3) particles is found to involve three overlapping processes.This work provides new routes to achieve scalable direct solar thermochemical heat storage for next-generation high-temperature solar power systems. | SONG Chao LIU XiangLei XUAN YiMin ZHENG HangBin GAO Ke TENG Liang DA Yun LI Chuan LI YongLiang DING YuLong | 2021 | Science China(Technological Sciences)2021，64，10： | 4 |
| 18 | Metal 2-Hydroxy-1-Naphthaldehyde Thiosemicarbazone (Me-HNT) Complexes-A New Kind of Biomimic Enzyme Catalyst显示文摘Metal (Me=Fe(III), Mo(VI), Mn(II), Co(II), Ni(II), Zn(II) and Cu(II)) 2-hydroxy-1 naphthaldehyde thiosemicarbazone complexes (MeHNT) were synthesized and used as mimic-enzyme catalysts to mimic the active group of horseradish peroxidase (HRP). The results showed that FeHNT. Mo-HNT are effective catalysts, which have similar catalytic activity as HRP. The sequence of catalytic activities of tested biomimic peroxidas is Mo-HNT> Fe-HNT > Zn-HNT > Ni-HNT > MnHNT. Among them. Fe-HNT is used as a mimic-enzyme catalyst in determination of ascorbic acid and glucose by coupling the catalytic reaction of glucose oxidase. | Ming DU Fang Zhen LIANG Bo TANG Yun Jing LUO Han Xi SHEN Bin TENG Yan LIU | 2000 | Chinese Chemical Letters2000，11，1： | 4 |
| 19 | Effect of garlic and garlic-green tea mixture on serum lipids in MNNG-induced experimental gastriccarcinoma and precancerous lesion显示文摘EfectofgarlicandgarlicgreenteamixtureonserumlipidsinMNNGinducedexperimentalgastriccarcinomaandprecancerouslesionSUQi,LUOZh... | SU Qi, LUO Zhao Yang, TENG Hua, YUN Wei Dong, Li Yi Qing and HE Xin E Institute of Oncology, Hengyang Medical College, Hengyang 421001, Hunan Province, China | 1998 | World Journal of Gastroenterology1998，4，1： | 4 |
| 20 | Optimal Scheduling for Combined District Heating and Power Systems Using Subsidy Strategies显示文摘The ongoing development of cogeneration technology has promoted public awareness on the integration of different types of energy systems.Integration of power and heating systems is the most common approach for energy transmission.The heat and power coupling of combined heat and power(CHP)units constrains the improvement of flexibility to accommodate more wind power,especially in winter.To address this problem,electrical boilers(EBs)are utilized as independent heat sources in one heat station to enhance their flexibility.This paper proposes a subsidy based bi-level optimal model.The objective of the upper problem is to minimize the operating cost,while the lower problem is to maximize the benefits of CHP and EBs based on the subsidy signals sent by the power system operator(PSO).The bi-level model is reformulated as a single-level linear problem by Karush Kuhn Turck(KKT)conditions and recast to a mix integer quadratic program using strong duality theory.Numerical results performed on an IEEE six-bus system with a eight-node district heating system validate the proposed model.The results demonstrate that the subsidy strategies can make the EB and CHP units operate according to the system operators’preferences to accommodate more wind power. | Bofu Deng Jiakun Fang Qian Hui Tieyan Zhang Zhe Chen Yun Teng Xiao Xi | 2019 | CSEE Journal of Power and Energy Systems2019，5，3： | 3 |
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